CN111658755A - Traditional Chinese medicine composition for clearing intestines before enteroscopy and preparation method thereof - Google Patents

Traditional Chinese medicine composition for clearing intestines before enteroscopy and preparation method thereof Download PDF

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CN111658755A
CN111658755A CN202010573188.4A CN202010573188A CN111658755A CN 111658755 A CN111658755 A CN 111658755A CN 202010573188 A CN202010573188 A CN 202010573188A CN 111658755 A CN111658755 A CN 111658755A
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chinese medicine
traditional chinese
medicine composition
enteroscopy
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赵玉斌
彭安堂
李玉婵
郭嘉璇
王津
吕一豪
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Shijiazhuang City Hospital
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/344Codonopsis
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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Abstract

The invention relates to a traditional Chinese medicine composition for clearing intestines before enteroscopy, which comprises the following components, by weight, 5-15 parts of rheum officinale, 2-15 parts of monkshood, 2-5 parts of asarum, 3-15 parts of angelica sinensis, 4-16 parts of dried ginger, 3-10 parts of ginseng, 2-9 parts of mirabilite, 3-10 parts of liquorice, 1-5 parts of croton, 3-7 parts of bunge cherry seed, 4-8 parts of codonopsis pilosula, 4-8 parts of bighead atractylodes rhizome, 4-8 parts of teasel root and 3-9 parts of fructus cannabis. The invention also provides a preparation method of the composition, the composition can effectively clean intestinal tracts before enteroscopy, and has small toxic and side effects and simple and convenient preparation method.

Description

Traditional Chinese medicine composition for clearing intestines before enteroscopy and preparation method thereof
Technical Field
The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for clearing intestines before enteroscopy and a preparation method thereof.
Background
The enteroscopy is a method for examining colon lesions by inserting an enteroscopy circulation cavity to the ileocecal part through the anus and observing the colon lesions from the side of the mucous membrane. The colon mucosa diagnosis instrument is the best choice for diagnosing large intestine mucosa lesion at present, and transmits the image of the colon mucosa to an electronic computer processing center through an electronic camera probe arranged at the front end of an enteroscope, and then displays the image on a monitor screen, so that tiny changes of the large intestine mucosa can be observed.
The cleanliness of the intestinal tract before enteroscopy is a key factor, and the preparation of the intestinal tract directly influences the effects of the intestinal examination and the treatment under the enteroscopy.
At present, before enteroscopy, the bowel-clearing medicines are mainly laxatives, and have obvious irritation and poor intestinal tract cleaning effect with small irritation, so that a traditional Chinese medicine composition capable of effectively cleaning intestinal tracts and having small irritation needs to be developed.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine composition for clearing intestines before enteroscopy, which can effectively clean intestines before enteroscopy, has small toxic and side effects and simple and convenient preparation method, and a preparation method thereof.
The technical scheme adopted by the invention is as follows: the invention provides a traditional Chinese medicine composition for clearing intestines before enteroscopy, which comprises the following components, by weight, 5-15 parts of rheum officinale, 2-15 parts of monkshood, 2-5 parts of asarum, 3-15 parts of angelica sinensis, 4-16 parts of dried ginger, 3-10 parts of ginseng, 2-9 parts of mirabilite, 3-10 parts of liquorice, 1-5 parts of croton, 3-7 parts of bunge cherry seed, 4-8 parts of codonopsis pilosula, 4-8 parts of bighead atractylodes rhizome, 4-8 parts of teasel root and 3-9 parts of fructus cannabis.
Further, the traditional Chinese medicine composition comprises 9 parts of rheum officinale, 12 parts of monkshood, 3 parts of asarum, 9 parts of angelica sinensis, 9 parts of dried ginger, 6 parts of ginseng, 6 parts of mirabilite, 6 parts of liquorice, 3 parts of croton, 4 parts of bunge cherry seed, 6 parts of codonopsis pilosula, 7 parts of bighead atractylodes rhizome, 5 parts of teasel root and 4 parts of fructus cannabis.
The invention also provides a preparation method of the traditional Chinese medicine composition for clearing bowels before enteroscopy, which comprises the following steps,
(1) weighing the components according to a preset proportion;
(2) weighing water which is 3-5 times of the total weight of the components in the step (1), putting the monkshood weighed in the step (1) into the water, decocting for 30min, adding the rest components in the step (1), boiling with strong fire, and keeping slight boiling with slow fire for 30 min;
(3) and (3) filtering the product obtained in the step (2), removing filter residues, naturally airing the filtrate to below 35 ℃, filling the filtrate into a disposable intestine clearing bag, and sealing and storing the bag for later use.
The raw material medicaments of the invention have the following effects:
rhubarb: bitter and cold. It enters spleen, stomach, large intestine, liver and pericardium meridians. Purgation and eliminating accumulation, clearing heat and purging fire, cooling blood and removing toxicity, removing blood stasis and dredging channels, promoting diuresis and eliminating jaundice.
Monkshood: pungent, sweet and big heat; is toxic. It enters heart, kidney and spleen meridians. Reviving yang and rescuing from collapse, tonifying fire and supporting yang, dispelling cold and relieving pain.
Asarum: pungent and warm with slight toxicity. It enters heart, lung and kidney meridians. The efficacy is as follows: relieving exterior syndrome, dispelling cold, dispelling pathogenic wind, relieving pain, dredging orifices, warming lung, and eliminating phlegm.
Chinese angelica: sweet, pungent and warm. It enters liver, heart and spleen meridians. The efficacy is as follows: enriching the blood; promoting blood circulation; regulating menstruation and relieving pain; moistening dryness and smoothing intestine. The main symptoms are blood deficiency; menoxenia; amenorrhea; dysmenorrhea; the accumulation of symptoms; (ii) metrorrhagia and metrostaxis; abdominal pain due to deficiency-cold; flaccidity and paralysis; numbness of the skin; intestinal dryness and difficult defecation; severe dysentery with diarrhea; carbuncle, cellulitis, sore and ulcer; injury from falling.
Dried ginger: pungent flavor and warm property. It enters spleen, stomach, kidney, heart and lung meridians. The efficacy is as follows: warming the middle energizer to dispel cold, restoring yang to activate collaterals, warming the lung to resolve retained fluid.
Ginseng: sweet and slightly bitter in taste, warm and mild in nature. It enters spleen, lung and heart meridians. The efficacy is as follows: tonify qi, secure collapse, promote fluid production, induce tranquilization, and promote intelligence.
Mirabilite: salty, bitter and cold in nature. It enters stomach and large intestine meridians. The efficacy is as follows: purgation, relaxing bowels, moistening dryness, softening hard masses, clearing away fire and relieving swelling.
Licorice root: sweet in flavor and neutral in nature. It enters heart, lung, spleen and stomach meridians. Has the effects of invigorating spleen and replenishing qi, clearing away heat and toxic materials, eliminating phlegm and stopping cough, relieving spasm and pain, and harmonizing the medicines.
Croton seed: purging cold accumulation, unblocking orifices, expelling phlegm, moving water and killing parasites. For cold accumulation and stagnation, fullness and pain in chest and abdomen, blood obstruction, phlegm nodule, dysentery and edema, it is used externally to treat laryngopathy, pharyngitis, sore, scabies and tinea.
The Chinese dwarf cherry seeds: it has mild nature and bitter and sweet taste, has the effects of moistening lung, smoothing intestine, promoting qi circulation and inducing diuresis, and can be used for treating symptoms such as large intestine qi stagnation, dryness, difficulty in micturition, abdominal edema, edema of limbs, and loempe.
Codonopsis pilosula: sweet in flavor and neutral in nature. Has effects in invigorating spleen, replenishing qi, quenching thirst, invigorating spleen, tonifying lung, nourishing blood, and promoting salivation. Can be used for treating deficiency of spleen-lung qi, anorexia, listlessness, cough, asthma, deficiency of qi and blood, sallow complexion, palpitation, short breath, thirst due to body fluid consumption, and internal heat.
White atractylodes rhizome: being bitter, warm, pungent and drastic in property, it has the actions of drying dampness, resolving turbidity and alleviating pain.
Teasel root: tonify liver and kidney, reunite bones and muscles, and regulate blood vessels. It is indicated for soreness of waist and back, weakness of foot and knee, fetal leakage, metrorrhagia, leukorrhagia, spermatorrhea, traumatic injury, incised wound, anal fistula, carbuncle, abscess, sore and swelling.
Fructus cannabis: sweet in flavor and neutral in nature. It enters spleen, stomach and large intestine meridians. The efficacy is as follows: to moisten intestines and relax bowels.
The usage and dosage of the invention are as follows:
the patient fasts dark-colored foods such as carrots, tomatoes, mangoes, mulberries, spinach, purple cabbages and the like within 24 hours before the enteroscopy, the patient does not forbid water within 12 hours, the patient starts to take 2000ml of the medicine warmly within 12 hours before the enteroscopy, 500ml of the medicine is taken every time of 30min, and 1000ml-2000ml of warm boiled water is taken after the patient finishes taking the medicine.
The invention has the beneficial effects that:
the invention is a warm agent, and is suitable for clearing intestines of patients with internal excess cold syndrome before enteroscopy.
The traditional Chinese medicine composition can be used for fully cleaning the intestinal tract before enteroscopy of a patient, ensures the quality of the enteroscopy, and is small in irritation to the organism of the patient, small in side effect, safe and effective.
Detailed Description
The following will explain the Chinese medicinal composition of the present invention in detail with reference to specific examples.
Example 1
Table 1 shows the Chinese medicinal composition for bowel cleansing before enteroscopy in the present invention.
TABLE 1 compositions of the Chinese medicinal compositions of examples 1-3
Figure 419125DEST_PATH_IMAGE001
The preparation method of example 1 is that it comprises the following steps,
(1) weighing the components according to a preset proportion;
(2) weighing water 4 times of the total weight of the components in the step (1), putting the monkshood weighed in the step (1) into the water, decocting for 30min, adding the rest components in the step (1), boiling with strong fire, and keeping slight boiling with slow fire for 30 min;
(3) and (3) filtering the product obtained in the step (2), removing filter residues, naturally airing the filtrate to below 35 ℃, filling the filtrate into a disposable intestine clearing bag, and sealing and storing the bag for later use. The disposable intestine-cleaning bag is a common product in anorectal department, and is also called a disposable enema bag or a disposable enema bag, and the like, which are all known to those skilled in the art.
The preparation method of the embodiment 2 is that the method comprises the following steps,
(1) weighing the components according to a preset proportion;
(2) weighing water which is 3 times of the total weight of the monkshood prepared in the step (1), putting the monkshood weighed in the step (1) into the water, decocting for 30min, adding the rest components prepared in the step (1), boiling with strong fire, and keeping slight boiling with slow fire for 30 min;
(3) and (3) filtering the product obtained in the step (2), removing filter residues, naturally airing the filtrate to below 35 ℃, filling the filtrate into a disposable intestine clearing bag, and sealing and storing the bag for later use. The disposable intestine-cleaning bag is a common product in anorectal department, and is also called a disposable enema bag or a disposable enema bag, and the like, which are all known to those skilled in the art.
The preparation method of the embodiment 3 is that the method comprises the following steps,
(1) weighing the components according to a preset proportion;
(2) weighing water which is 5 times of the total weight of the monkshood prepared in the step (1), putting the monkshood weighed in the step (1) into the water, decocting for 30min, adding the rest components prepared in the step (1), boiling with strong fire, and keeping slight boiling with slow fire for 30 min;
(3) and (3) filtering the product obtained in the step (2), removing filter residues, naturally airing the filtrate to below 35 ℃, filling the filtrate into a disposable intestine clearing bag, and sealing and storing the bag for later use. The disposable intestine-cleaning bag is a common product in anorectal department, and is also called a disposable enema bag or a disposable enema bag, and the like, which are all known to those skilled in the art.
Standard of therapeutic effect and therapeutic result
Diagnostic criteria: the enteroscopy was performed after taking the product of example 1 of the present invention before the enteroscopy. Using the object: the patients with interior excess cold syndrome who come to visit before the clinic.
During enteroscopy, the intestinal cleanliness is good, and the patient has no discomfort in intestines and stomach and is marked as 'excellent';
during enteroscopy, the intestinal cleanliness is taught well, and patients have no obvious gastrointestinal discomfort and slight discomfort or are marked as 'good';
during enteroscopy, the cleanliness of the intestinal tract is poor, and the patient has obvious gastrointestinal discomfort and is marked as 'bad';
the traditional Chinese medicine composition for clearing bowels is used for 100 patients before enteroscopy, the traditional Chinese medicine composition for clearing bowels and the using method thereof are used, and then the conventional enteroscopy is carried out, wherein in the enteroscopy, 68 excellent patients, 25 good patients and 7 bad patients exist, and the total effective rate is 93%.

Claims (3)

1. A traditional Chinese medicine composition for clearing intestines before enteroscopy is characterized in that: the traditional Chinese medicine composition comprises, by weight, 5-15 parts of rheum officinale, 2-15 parts of monkshood, 2-5 parts of asarum, 3-15 parts of angelica sinensis, 4-16 parts of dried ginger, 3-10 parts of ginseng, 2-9 parts of mirabilite, 3-10 parts of liquorice, 1-5 parts of croton, 3-7 parts of bunge cherry seed, 4-8 parts of codonopsis pilosula, 4-8 parts of bighead atractylodes rhizome, 4-8 parts of teasel root and 3-9 parts of fructus cannabis.
2. The traditional Chinese medicine composition for bowel cleansing before enteroscopy according to claim 1, which is characterized in that: the traditional Chinese medicine composition comprises the following components of 9 parts of rheum officinale, 12 parts of monkshood, 3 parts of asarum, 9 parts of angelica sinensis, 9 parts of dried ginger, 6 parts of ginseng, 6 parts of mirabilite, 6 parts of liquorice, 3 parts of croton, 4 parts of bunge cherry seed, 6 parts of codonopsis pilosula, 7 parts of bighead atractylodes rhizome, 5 parts of teasel root and 4 parts of fructus cannabis.
3. The method for preparing a Chinese medicinal composition for bowel cleansing before enteroscopy according to any one of claims 1 to 2, which is characterized in that: which comprises the following steps of,
(1) weighing the components according to a preset proportion;
(2) weighing water which is 3-5 times of the total weight of the components in the step (1), putting the monkshood weighed in the step (1) into the water, decocting for 30min, adding the rest components in the step (1), boiling with strong fire, and keeping slight boiling with slow fire for 30 min;
(3) filtering to remove residue, naturally cooling the filtrate to below 35 deg.C, packaging into disposable clear intestine bag, and sealing for storage.
CN202010573188.4A 2020-04-13 2020-06-22 Traditional Chinese medicine composition for clearing intestines before enteroscopy and preparation method thereof Pending CN111658755A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104645068A (en) * 2015-02-05 2015-05-27 李华子 Enema for treatment of radiation proctitis
CN109091554A (en) * 2018-09-30 2018-12-28 张雷 A kind of drug for treating constipation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104645068A (en) * 2015-02-05 2015-05-27 李华子 Enema for treatment of radiation proctitis
CN109091554A (en) * 2018-09-30 2018-12-28 张雷 A kind of drug for treating constipation

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
郑仕诚 主编: "《消化系统常见疾病基层医生误诊防范手册》", 30 June 2012, 四川科学技术出版社 *
马少丹 主编: "《实用中医经典方荟萃》", 31 August 2017 *

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Application publication date: 20200915

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