CN111658751A - External application plaster for treating lumbar intervertebral disc protrusion and hyperplasia and preparation method thereof - Google Patents

External application plaster for treating lumbar intervertebral disc protrusion and hyperplasia and preparation method thereof Download PDF

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CN111658751A
CN111658751A CN202010465729.1A CN202010465729A CN111658751A CN 111658751 A CN111658751 A CN 111658751A CN 202010465729 A CN202010465729 A CN 202010465729A CN 111658751 A CN111658751 A CN 111658751A
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paste
hyperplasia
rhubarb
scallion
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韩雪钰
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708Rheum (rhubarb)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8962Allium, e.g. garden onion, leek, garlic or chives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/04Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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Abstract

An external application plaster for treating lumbar intervertebral disc protrusion and hyperplasia and a preparation method thereof belong to medical medicines; the medicament formula is prepared by matching rhubarb, ginger, starch, white spirit, food-grade sodium propionate or potassium sorbate, food-grade pigment and water according to different weight ratios; processing rhubarb and ginger into rhubarb powder and ginger powder respectively, heating and frying scallion to be half cooked, smashing to be scallion paste, mixing the rhubarb powder, the ginger powder and the scallion paste with starch, white spirit, food-grade sodium propionate or potassium sorbate and food-grade pigment, uniformly stirring to obtain mixed raw materials, adding water into the mixed raw materials, stirring to obtain a paste medicament, quantitatively spreading the paste medicament on medical support cloth with glue to obtain the lumbar prominence and hyperplasia external application plaster; the patch has the advantages of safe and reliable use, no toxic or side effect, strong applicability, good treatment effect, high cure rate, quick response, low treatment cost, simple preparation method, simple and convenient use and no pain in treatment.

Description

External application plaster for treating lumbar intervertebral disc protrusion and hyperplasia and preparation method thereof
Technical Field
The invention belongs to medical medicines, and mainly relates to an external application plaster for treating lumbar disc herniation and hyperosteogeny.
Background
With the increase of the age, orthopedic diseases caused by the change of bones and structures of human bodies are continuously generated. Especially in recent years, the development and progress of science and technology have led to great changes in human life and work patterns. When people get lost to the mobile phone and the computer, the influence is brought to the human body, the incidence rate of lumbar vertebra, cervical vertebra and scapulohumeral periarthritis is greatly improved, and the trend of youthfulness is presented. Wherein, the lumbar disc herniation and the hyperosteogeny disease occupy a very high proportion, which causes great pain and injury to human bodies.
To solve the above problems, the current treatment methods in the world use either conservative physical therapy or surgical treatment. Conservative physical therapy only can play a role in temporary relief, cannot cure radically and is easy to attack repeatedly. The trauma and the risk of the operation treatment are large, the recurrence rate after the operation is high, sequela is also generated, not only is a small economic burden brought to a patient, but also great pain and psychological stress are brought to the patient. In conclusion, although the treatment methods are more, the treatment methods are difficult and have different insights, and the ideal curative effect is not obtained.
To the best of the applicant's knowledge, no external medicine for treating lumbar protrusion and hyperplasia diseases without surgery has been developed and applied in clinical treatment.
Disclosure of Invention
Aiming at the problems in the prior art, the invention researches an external application for lumbar intervertebral disc protrusion and hyperosteogeny and a preparation method thereof by combining the actual requirements of treatment of lumbar intervertebral disc protrusion and hyperosteogeny diseases, and achieves the purposes of good treatment effect, high cure rate, short treatment time, quick response, low treatment cost, strong treatment applicability and wide treatment range.
The purpose of the invention is realized as follows:
an external application plaster for treating lumbar intervertebral disc protrusion and hyperplasia, wherein the medicament formula of the external application plaster for treating lumbar intervertebral disc protrusion and hyperplasia is prepared from 80 parts of rhubarb, 8 parts of ginger, 8 parts of starch, 10 parts of shallot, 20 parts of white spirit, 2 parts of food-grade sodium propionate or potassium sorbate, 0.5 part of food-grade pigment and 132 parts of water in a compatible manner.
The preparation method of the lumbar intervertebral disc protrusion and hyperplasia external application comprises the following steps:
firstly, processing rhubarb and ginger into powder respectively to obtain rhubarb powder and ginger powder for later use;
heating and frying the scallion until the scallion is half-cooked, immediately stopping heating, and mashing the scallion of the half-cooked rehmannia into paste to obtain the scallion paste for later use;
thirdly, mixing the rhubarb powder and the ginger powder prepared in the first step and the green onion paste prepared in the second step with starch, white spirit, food-grade sodium propionate or potassium sorbate and food-grade pigment, and uniformly stirring to obtain mixed raw materials;
adding water into the mixed raw materials, and stirring to obtain a paste medicament;
fifthly, quantitatively spreading the paste medicament on a medical support cloth with glue to obtain the lumbar prominence and hyperplasia external application.
In the medicinal components, the rhubarb has the main effects of treating diarrhea, eliminating carbuncle, eliminating stasis, promoting blood circulation and removing stasis, and has the main functions of detumescence, antiphlogosis and acesodyne; the ginger plays a role in dispelling cold; the main functions of the scallion and the white spirit are to promote blood circulation; the food-grade pigment has the functions of improving the skin permeation of the medicine and enhancing the treatment effect; the starch is used for binding the medicinal components, and the food-grade sodium propionate or potassium sorbate is a preservative, so that the shelf life of the medicament can be effectively prolonged, and the medicament is prevented from deteriorating. In particular, the above conventional materials are mixed together to cause a physical and chemical reaction, which plays an unprecedented role. The practical and effective treatment effect is discovered in a breakthrough manner in the treatment of the osteopathy of the lumbar disc herniation and the hyperosteogeny.
The invention adopts nontoxic, non-side effect, safe and reliable edible materials as the main components of the medicine, is a special specific external application medicine for treating lumbar disc herniation, spinal stenosis, cartilage calcification, cervical spondylosis, hyperosteogeny and bony spur, can be used for treating ligament and soft tissue calcification and lumbar muscle strain diseases, and has the characteristics of safe and reliable use, strong applicability, good treatment effect, high cure rate, quick response, low treatment cost, simple preparation method, simple and convenient use and no pain in treatment.
Detailed Description
The technical solution of the present invention is described in detail below.
An external application plaster for treating lumbar intervertebral disc protrusion and hyperplasia, wherein the medicament formula of the external application plaster for treating lumbar intervertebral disc protrusion and hyperplasia is prepared from 80 parts of rhubarb, 8 parts of ginger, 8 parts of starch, 10 parts of shallot, 20 parts of white spirit, 2 parts of food-grade sodium propionate or potassium sorbate, 0.5 part of food-grade pigment and 132 parts of water in a compatible manner.
The preparation method of the lumbar intervertebral disc protrusion and hyperplasia external application comprises the following steps:
firstly, processing rhubarb and ginger into powder respectively to obtain rhubarb powder and ginger powder for later use;
heating and frying the scallion until the scallion is half-cooked, immediately stopping heating, and mashing the scallion of the half-cooked rehmannia into paste to obtain the scallion paste for later use;
thirdly, mixing the rhubarb powder and the ginger powder prepared in the first step and the green onion paste prepared in the second step with starch, white spirit, food-grade sodium propionate or potassium sorbate and food-grade pigment, and uniformly stirring to obtain mixed raw materials;
adding water into the mixed raw materials, and stirring to obtain a paste medicament;
fifthly, quantitatively spreading the paste medicament on a medical support cloth with glue to obtain the lumbar prominence and hyperplasia external application.
The application method of the lumbar vertebra disease and hyperplasia external application comprises the following steps: the patch is applied once a day at night, the first patch is lightly taken out after being applied for 24 hours, the skin is cleaned by warm clear water and is wiped dry, and a new patch is applied after 12 hours. The second patch is taken down after 12 hours, new patches are attached after 12 hours, one course of treatment is 5 patches, a course of treatment is generally required for new patients, and one to two courses of treatment are required for old patients. Can take effect for patients with knee joint hyperplasia and bony spur by continuously using more than two treatment courses. When the patch is attached to the skin, the patch is firmly adhered to ensure the curative effect. In use, the external application can soften, gradually atrophy and absorb the hyperplastic lesion part, and after a period of time, the external application shows an obvious improvement effect. In the process of treatment and rehabilitation, patients feel that the pain is relieved and the bodies are comfortable, and the pain is obviously improved in 5-7 days, and the effect is obtained. Research experiment statistics shows that the cure rate of the lumbar intervertebral disc for patients with lumbar intervertebral disc prolapse and hyperplasia is more than 90%, the recurrence rate is low, no side effect is caused, and the safety is good.
Case brief introduction of clinical laboratory
Figure RE-GSB0000188700260000011

Claims (2)

1. An external application plaster for lumbar vertebra protrusion and hyperplasia is characterized in that: the formula of the externally applied medicine for treating lumbar intervertebral disc protrusion and hyperplasia consists of 80 parts of rhubarb, 8 parts of ginger, 8 parts of starch, 10 parts of green onion, 20 parts of white spirit, 2 parts of food-grade sodium propionate or potassium sorbate, 0.5 part of food-grade pigment and 132 parts of water in the same weight ratio.
2. The method for preparing an externally-applied plaster for treating lumbar intervertebral disc protrusion and hyperplasia according to claim 1, wherein:
firstly, processing rhubarb and ginger into powder respectively to obtain rhubarb powder and ginger powder for later use;
heating and frying the scallion until the scallion is half-cooked, immediately stopping heating, and mashing the scallion of the half-cooked rehmannia into paste to obtain the scallion paste for later use;
thirdly, mixing the rhubarb powder and the ginger powder prepared in the first step and the green onion paste prepared in the second step with starch, white spirit, food-grade sodium propionate or potassium sorbate and food-grade pigment, and uniformly stirring to obtain mixed raw materials;
adding water into the mixed raw materials, and stirring to obtain a paste medicament;
fifthly, quantitatively spreading the paste medicament on a medical support cloth with glue to obtain the lumbar prominence and hyperplasia external application.
CN202010465729.1A 2020-05-22 2020-05-22 External application plaster for treating lumbar intervertebral disc protrusion and hyperplasia and preparation method thereof Withdrawn CN111658751A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010465729.1A CN111658751A (en) 2020-05-22 2020-05-22 External application plaster for treating lumbar intervertebral disc protrusion and hyperplasia and preparation method thereof

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Application Number Priority Date Filing Date Title
CN202010465729.1A CN111658751A (en) 2020-05-22 2020-05-22 External application plaster for treating lumbar intervertebral disc protrusion and hyperplasia and preparation method thereof

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Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
樊成虎等主编: "《脊柱创伤与疾患中西医结合诊疗学》", 31 May 2016 *
陈志鹏主编: "《袖珍中草药彩色图谱》", 31 October 2016 *

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Application publication date: 20200915