Summary of the invention
The object of the invention is to the Chinese medicine composition that a kind of fast fracture-setting is provided for the various problem occurred when the doctor trained in Western medicine of above-mentioned existence and Chinese traditional treatment fracture, solve that Chinese medicine side's reducing swelling and alleviating pain is slow, the course for the treatment of is long, the dissatisfactory shortcoming of effect, while blood circulation promoting and blood stasis dispelling, dredging through invigorating blood circulation, activating the bone lengthening factor.Simultaneously due to the existence of tying-in medicine, make medicine intensively can be gathered in fracture site more fast, therapeutic effect is more remarkable.
The traditional Chinese medical science thinks that trauma fracture will inevitably cause meridians in body, vim and vigour and relevant dysfunction thereof, causes vim and vigour all to hinder, necessary QI and blood regulating meridians while treatment trauma fracture, reducing swelling and alleviating pain, blood circulation promoting and blood stasis dispelling.The present invention is by conditioning for oral administration, and promoting blood circulation and stopping pain, hemostasia and promoting granulation, warming the kidney to activate YANG, the liver and the kidney tonifying, blood-activating and qi-promoting, again by tying-in medicine, make medicine through focus fast, bone-setting pain stopping effect is very good.
Another technical problem dosage form being to provide this Chinese medicine to be solved by this invention and preparation method thereof.
Technical scheme of the present invention is as follows:
A Chinese medicine composition for fast fracture-setting, is made up of the raw material of Chinese medicine medicine of following weight portion: Radix Angelicae Sinensis 40-60 part, Lignum Dalbergiae Odoriferae 40-60 part, Rhizoma Drynariae 20-40 part, catechu 20-40 part, Cortex Lycii 40-60 part, Radix Et Rhizoma Rhei 10-30 part, Olibanum 10-30 part, Myrrha 10-30 part, Sanguis Draxonis 20-40 part, Stigma Croci 5-20 part, eupolyphage sece steleophaga 20-40 part, Semen Persicae 10-30 part, Realgar 20-40 part, Radix Ephedrae 20-40 part, Pyritum 15-40 part, chicken bone 40-60 part.
As preferably, the Chinese medicine composition of above-mentioned fast fracture-setting, is made up of the raw material of Chinese medicine medicine of following weight portion: Radix Angelicae Sinensis 40 parts, Lignum Dalbergiae Odoriferae 45 parts, Rhizoma Drynariae 25 parts, 25 parts, catechu, Cortex Lycii 50 parts, Radix Et Rhizoma Rhei 20 parts, Olibanum 25 parts, Myrrha 25 parts, Sanguis Draxonis 25 parts, Stigma Croci 5 parts, eupolyphage sece steleophaga 25 parts, 15 parts, Semen Persicae, Realgar 25 parts, Radix Ephedrae 25 parts, Pyritum 30 parts, chicken bone 55 parts.
As preferably, the Chinese medicine composition of above-mentioned fast fracture-setting, is made up of the raw material of Chinese medicine medicine of following weight portion: Radix Angelicae Sinensis 50 parts, Lignum Dalbergiae Odoriferae 50 parts, Rhizoma Drynariae 30 parts, 30 parts, catechu, Cortex Lycii 50 parts, Radix Et Rhizoma Rhei 20 parts, Olibanum 20 parts, Myrrha 15 parts, Sanguis Draxonis 30 parts, Stigma Croci 10 parts, eupolyphage sece steleophaga 30 parts, 20 parts, Semen Persicae, Realgar 25 parts, Radix Ephedrae 20 parts, Pyritum 20 parts, chicken bone 60 parts.
Due to middle-aged and elderly people insufficiency of vital energy and blood, in order to improve curative effect further, as preferably, the Chinese medicine composition of above-mentioned fast fracture-setting also comprises Radix Notoginseng 5-30 part and Cornu Cervi Degelatinatum 5-30 part.
In order to make medicine through focus fast, as preferably, the tying-in medicine of above-mentioned fast fracture-setting Chinese medicine composition is respectively according to the position difference of fracture: extremity position-Radix Achyranthis Bidentatae 10-30 part, trunk-Rhizoma Chuanxiong 10-30 part, Head And Face-Ramulus Cinnamomi 10-30 part.
Preferred as extremity position, the Chinese medicine composition of above-mentioned fast fracture-setting, is made up of the raw material of Chinese medicine medicine of following weight portion: Radix Angelicae Sinensis 50 parts, Lignum Dalbergiae Odoriferae 50 parts, Rhizoma Drynariae 30 parts, 30 parts, catechu, Cortex Lycii 50 parts, Radix Et Rhizoma Rhei 20 parts, Olibanum 20 parts, Myrrha 15 parts, Sanguis Draxonis 30 parts, Stigma Croci 5 parts, eupolyphage sece steleophaga 30 parts, 20 parts, Semen Persicae, Realgar 25 parts, Radix Ephedrae 20 parts, Pyritum 20 parts, chicken bone 60 parts, Radix Notoginseng 20 parts, Cornu Cervi Degelatinatum 5 parts, Radix Achyranthis Bidentatae 20 parts.
Preferred as extremity position, the Chinese medicine composition of above-mentioned fast fracture-setting, is made up of the raw material of Chinese medicine medicine of following weight portion: Radix Angelicae Sinensis 50 parts, Lignum Dalbergiae Odoriferae 50 parts, Rhizoma Drynariae 30 parts, 30 parts, catechu, Cortex Lycii 50 parts, Radix Et Rhizoma Rhei 20 parts, Olibanum 20 parts, Myrrha 20 parts, Sanguis Draxonis 30 parts, Stigma Croci 10 parts, eupolyphage sece steleophaga 30 parts, 20 parts, Semen Persicae, Realgar 30 parts, Radix Ephedrae 30 parts, Pyritum 30 parts, chicken bone 60 parts, Radix Notoginseng 20 parts, Cornu Cervi Degelatinatum 15 parts, Radix Achyranthis Bidentatae 25 parts.
Preferred as metastomium, the Chinese medicine composition of above-mentioned fast fracture-setting, is made up of the raw material of Chinese medicine medicine of following weight portion: Radix Angelicae Sinensis 50 parts, Lignum Dalbergiae Odoriferae 50 parts, Rhizoma Drynariae 30 parts, 30 parts, catechu, Cortex Lycii 50 parts, Radix Et Rhizoma Rhei 20 parts, Olibanum 20 parts, Myrrha 15 parts, Sanguis Draxonis 30 parts, Stigma Croci 5 parts, eupolyphage sece steleophaga 30 parts, 20 parts, Semen Persicae, Realgar 25 parts, Radix Ephedrae 20 parts, Pyritum 20 parts, chicken bone 60 parts, Radix Notoginseng 20 parts, Cornu Cervi Degelatinatum 5 parts, Rhizoma Chuanxiong 20 parts.
Preferred as metastomium, the Chinese medicine composition of above-mentioned fast fracture-setting, is made up of the raw material of Chinese medicine medicine of following weight portion: Radix Angelicae Sinensis 50 parts, Lignum Dalbergiae Odoriferae 50 parts, Rhizoma Drynariae 30 parts, 30 parts, catechu, Cortex Lycii 50 parts, Radix Et Rhizoma Rhei 20 parts, Olibanum 20 parts, Myrrha 20 parts, Sanguis Draxonis 30 parts, Stigma Croci 10 parts, eupolyphage sece steleophaga 30 parts, 20 parts, Semen Persicae, Realgar 30 parts, Radix Ephedrae 30 parts, Pyritum 30 parts, chicken bone 60 parts, Radix Notoginseng 20 parts, Cornu Cervi Degelatinatum 15 parts, Rhizoma Chuanxiong 25 parts.
Preferred as women's head-ornaments position, the Chinese medicine composition of above-mentioned fast fracture-setting, is made up of the raw material of Chinese medicine medicine of following weight portion: Radix Angelicae Sinensis 50 parts, Lignum Dalbergiae Odoriferae 50 parts, Rhizoma Drynariae 30 parts, 30 parts, catechu, Cortex Lycii 50 parts, Radix Et Rhizoma Rhei 20 parts, Olibanum 20 parts, Myrrha 15 parts, Sanguis Draxonis 30 parts, Stigma Croci 5 parts, eupolyphage sece steleophaga 30 parts, 20 parts, Semen Persicae, Realgar 25 parts, Radix Ephedrae 20 parts, Pyritum 20 parts, chicken bone 60 parts, Radix Notoginseng 20 parts, Cornu Cervi Degelatinatum 5 parts, Ramulus Cinnamomi 20 parts.
Preferred as women's head-ornaments position, the Chinese medicine composition of above-mentioned fast fracture-setting, is made up of the raw material of Chinese medicine medicine of following weight portion: Radix Angelicae Sinensis 50 parts, Lignum Dalbergiae Odoriferae 50 parts, Rhizoma Drynariae 30 parts, 30 parts, catechu, Cortex Lycii 50 parts, Radix Et Rhizoma Rhei 20 parts, Olibanum 20 parts, Myrrha 20 parts, Sanguis Draxonis 30 parts, Stigma Croci 10 parts, eupolyphage sece steleophaga 30 parts, 20 parts, Semen Persicae, Realgar 30 parts, Radix Ephedrae 30 parts, Pyritum 30 parts, chicken bone 60 parts, Radix Notoginseng 20 parts, Cornu Cervi Degelatinatum 15 parts, Ramulus Cinnamomi 25 parts.
The preparation method of the Chinese medicine composition of above-mentioned fast fracture-setting, comprises following steps:
A. take appropriate Radix Ephedrae and put into iron pan, fry to rubescent;
B. Semen Persicae is removed tip;
C. by above-mentioned each component medicine and guiding drug pulverization respectively, 130 mesh sieves are crossed;
D. by the smalls mixing and stirring that step c is obtained, finished product can be obtained.
As preferably, obtained smalls finished product can also be added proper honey, finished product pill can be obtained.
Product carries out quality inspection, after the assay was approved package sterilization.Finished product smalls, every auxiliary medicine is 60 parts, and every part, containing crude drug in whole 9g, takes 2 every day, each 1 part.Finished product pill medicament, every auxiliary medicine is 60 balls, and every pill, containing crude drug in whole 9g, takes 2 every day, each 1.
Note and taboo: when the present invention takes, Chinese liquor or yellow wine take; Gynecologic menstrual, anemia of pregnant woman forbid taking; Fracture in latter 24 hours and can not take; During taking this medicine, cool peppery, the beans of raw food can not be eaten.
Function of the present invention cures mainly:
Various fracture, pull, sprain, osteomyelitis, sticky sore leg.
The pharmacological action of formula of the present invention:
Chinese angelica blood supplementing is invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Be used for the treatment of blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down, ulcer sores, dryness of the intestine constipation.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.
Lignum Dalbergiae Odoriferae removing stasis to stop bleeding, regulating QI to relieve pain.Be used for the treatment of haematemesis, epistaxis, traumatic hemorrhage, hypochondriac pain due to stagnation of liverQI, thoracic obstruction twinge, falls and flutters the pain of injury, vomiting stomachache.
Rhizoma Drynariae is cured the wound pain relieving, the kidney invigorating bone strengthening; External pathogenic wind expelling speckle dispelling.Be used for the treatment of that falling winks frustrates, injured bone, lumbago due to renal deficiency, muscles and bones is withered soft, Hiccough and deaf, odontoseisis; External treatment alopecia areata, vitiligo.
Catechu promoting blood circulation and stopping pain, hemostasia and promoting granulation, removing dampness sore, removing heat from the lung and dissipating phlegm.Be used for the treatment of to fall and flutter the pain of injury, traumatic hemorrhage, hematemesis and epistaxis, skin infection is not held back, eczema, eczema, cough due to lung-heat.
Cortex Lycii removing heat from blood removes and steams, lung heat clearing pathogenic fire reducing.Be used for the treatment of deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat, cough due to lung-heat, spitting of blood, epistaxis, interior-heat is quenched one's thirst.
Radix Et Rhizoma Rhei heat and toxic materials clearing away, clearing away heat-fire, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation, dampness removing jaundice eliminating.Be used for the treatment of excess-heat to stagnate constipation, heat in blood tells nosebleed, conjunctival congestion pharyngeal swelling, carbuncle furuncle, abdominalgia with intestinal abscess, blood stasis amenorrhea, postpartum stagnation, traumatic injury, hygropyretic dysentery, jaundice dark coloured urine, stranguria, edema; Externally treating burns and scalds.Radix et Rhizoma Rhei (stir-fried with wine) is apt to clear part of the body cavity above the diaphragm housing the heart and lungs noxious heat in the blood system.For conjunctival congestion pharyngeal swelling, gingivitis.Radix Et Rhizoma Rhei rushes down exerts oneself to delay, eliminating fire and detoxication.For pathogenic fire,toxin and furuncles.Charred Radix Et Rhizoma Rhei cooling blood and removing stasis stops blooding.Stasis of blood hemorrhage is had for heat in blood.
Olibanum is invigorated blood circulation analgesic therapy, detumescence and promoting granulation.Be used for the treatment of obstruction of qi in the chest and cardialgia, gastralgia, dysmenorrhea amenorrhea, postpartum stagnation , mass in the abdomen is suffered from abdominal pain, rheumatic arthralgia, the contracture of muscle arteries and veins, traumatic injury, carbuncle skin infection.
The analgesic therapy of Myrrha dissipating blood stasis, detumescence and promoting granulation.Be used for the treatment of obstruction of qi in the chest and cardialgia, gastralgia, dysmenorrhea amenorrhea, postpartum stagnation , mass in the abdomen is suffered from abdominal pain, rheumatic arthralgia, traumatic injury, carbuncle skin infection.
Sanguis Draxonis is invigorated blood circulation analgesic therapy, removing stasis to stop bleeding, promoting tissue regeneration and ulcer healing.Be used for the treatment of traumatic injury, trusted subordinate's stasis of blood pain, traumatic hemorrhage, skin infection is not held back.
Stigma Croci blood circulation promoting and blood stasis dispelling, removing pathogenic heat from blood and toxic substance from the body, resolving stagnation for tranquilization.Be used for the treatment of amenorrhea and mass in the abdomen, postpartum stagnation, maculae caused by violent heat pathogen, melancholy painful abdominal mass is vexed, and palpitation with fear is gone mad.
Eupolyphage sece steleophaga removing blood stasis, reunion of fractured tendons and bones.Be used for the treatment of traumatic injury, the injury of tendon and muscle is fractured, blood stasis amenorrhea, postpartum stagnation stomachache , mass in the abdomen mass in the abdomen.
Semen Persicae blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, relieving cough and asthma.Be used for the treatment of amenorrhea dysmenorrhea , mass in the abdomen mass in the abdomen, lung abscess acute appendicitis, injury from falling down, dryness of the intestine constipation, cough and asthma.
Realgar removing toxic substances parasite killing, removing dampness and eliminating phlegm, preventing the attack (or recurrence) of malaria.Be used for the treatment of carbuncle furuncle, snake bite and insect sting, abdominal pain due to worm stagnation, infantile convulsion, malaria.
Radix Ephedrae strengthening superficial resistance to stop perspiration.Be used for the treatment of spontaneous perspiration, night sweat.
Pyritum eliminating stasis to stop pain, reunion of fractured tendons and bones.Be used for the treatment of traumatic injury, injured bone, pain caused by ecchymoma.
Chicken bone supplements trace element and the protein such as calcium phosphorus, builds bone, activates the bone lengthening factor.
Radix Notoginseng dissipating blood stasis stops blooding, subduing swelling and relieving pain.Be used for the treatment of spitting of blood, spit blood, epistaxis, has blood in stool, metrorrhagia, traumatic hemorrhage, breast ventral spine pain, tumbling and swelling.
Cornu Cervi Degelatinatum warming the kidney to activate YANG, astringing to arrest bleeding.Be used for the treatment of deficiency of spleen-YANG and kidneyYANG, leukorrhagia, enuresis frequent micturition, metrostaxis, skin infection is not held back.
Radix Achyranthis Bidentatae returns liver, kidney channel.Eliminating blood stasis and inducing menstruation, invigorating the liver and kidney, bone and muscle strengthening, inducing diuresis for treating stranguria syndrome, conducting blood to flow downwards.Be used for the treatment of amenorrhea, dysmenorrhea, soreness of waist and knee joint, muscles and bones is unable, stranguria, edema, headache, dizzy, toothache, and aphtha is spitted blood, epistaxis.
Ramulus Cinnamomi GUIXIN, lung, urinary bladder channel.Diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, making the adverse-rising QI downwards.Be used for the treatment of anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.
Rhizoma Chuanxiong returns liver, gallbladder, pericardium channel.Blood-activating and qi-promoting, wind-expelling pain-stopping.Be used for the treatment of obstruction of qi in the chest and cardialgia, the twinge of the breast side of body, tumbling and swelling, menoxenia, amenorrhea dysmenorrhea , mass in the abdomen is suffered from abdominal pain, headache, rheumatic arthralgia.
The invention has the beneficial effects as follows:
(1) blood circulation promoting and blood stasis dispelling synthetism of the present invention is effective.The present invention is Traditional Chinese medical theory by reference, by conditioning for oral administration, and promoting blood circulation and stopping pain, hemostasia and promoting granulation, warming the kidney to activate YANG, the liver and the kidney tonifying, blood-activating and qi-promoting, again by tying-in medicine, use different tying-in medicines for different disease sites, make medicine through focus fast, bone-setting pain stopping effect is very good.For fracture patient, taking after the present invention general 1-2 days can reducing swelling and alleviating pain, clamping plate of can dismantling for 7-9 days, normal activity of can fully recovering for 1 month.
(2) invention formulation is pill shape, and avoiding decocting for Chinese herbal medicine wastes time and energy and decoct the duration and degree of heating and hold and forbidden, be long placed in and easily mouldly lose rotten shortcoming, inserts the bitterness that Mel also can cover Chinese medicine, conveniently takes.
(3) therapy of the present invention to fracture be do not operate on, not planter cast, within one month, can return to one's perfect health for common fracture, short treating period, cure rate is high, for the working learning life of patient and household alleviates burden, reduce the misery bringing patient in treatment, and expense cost is low.
(4) the present invention to osteomyelitis, pull, to sprain and sticky sore leg also has good curative effect.For pulling and spraining, general 1-2 days can reducing swelling and alleviating pain, can cure completely within 7 days.For osteomyelitis general patient, also can return to one's perfect health within one month.For sticky sore leg patient, take 1-2 days skin ulcer faces and start to improve, can return to one's perfect health in one month.
Embodiment 16:
Get the raw material of Chinese medicine of following quality: Radix Angelicae Sinensis 40 parts, Lignum Dalbergiae Odoriferae 45 parts, Rhizoma Drynariae 25 parts, 25 parts, catechu, Cortex Lycii 50 parts, Radix Et Rhizoma Rhei 20 parts, Olibanum 25 parts, Myrrha 25 parts, Sanguis Draxonis 25 parts, Stigma Croci 5 parts, eupolyphage sece steleophaga 25 parts, 15 parts, Semen Persicae, Realgar 25 parts, Radix Ephedrae 25 parts, Pyritum 30 parts, chicken bone 55 parts.First Radix Ephedrae is put into iron pan, fry to rubescent; Again Semen Persicae is removed tip; Then by above-mentioned each component medicine, 130 mesh sieves are crossed; The smalls mixing and stirring of will sift out again; Finally smalls is added proper honey, make pill, can finished product be obtained.
Clinical pharrnacokinetics is tested:
For fractured leg, what participate in experiment is 120 altogether, by age be divided into 10-30 year group, 31-40 year group and 51-70 year group, three groups of participants are divided into 4 groups according to the principle of stochastic sampling, clinical pharrnacokinetics test is carried out to the preparation of embodiments of the invention 2, embodiment 10, embodiment 16 and matched group bone-connecting pill, has been produced as follows form according to the average cured time of each group:
Matched group bone-connecting pill authentication code: traditional Chinese medicines accurate word Z22020499,2010-05-20.Production unit: daylight pharmaceutcal corporation, Ltd of Jilin Province.Medicine characteristic: Chinese medicine.Main Ingredients and Appearance is Semen Melo, Eupolyphaga Seu Steleophaga, Pyritum, Pheretima, Radix Curcumae, Semen Strychni Pulveratum, Ramulus Cinnamomi, Radix Dipsaci.Oral, a 3g, 2 times on the one.
As can be seen from the above table, the healing time of the present invention couple and fracture far less than common synthetism prescription, as can be seen from the table: do not use the embodiment 16 of tying-in medicine also can treat fracture, and the speed also faster than common showy reiolaena root-bark several days of recovery from illness; Compared with embodiment 16, the tying-in medicine increased in embodiment 2 can promote that medicine gos deep into focus greatly, concentrates more efficacy of a drug treatment fracture, improves recovery from illness speed; Compared with embodiment 2, the Radix Notoginseng increased in embodiment 10 and Cornu Cervi Degelatinatum can promote the speed of fracture union of middle-aged and elderly people.
Typical case:
(1) Hu, man, 16 years old, senior middle school student at school, accidentally fell down arm fracture, after resetting, uses Chinese medicine of the present invention to treat when physical education is run, and after taking surrounding, in hospital, taking X-ray display fracture site is fully recovered.
(2) Liu, man, 62 years old, retired worker, went out when having a walk and accidentally fall down morning, and arm is fractured, and after resetting, used Chinese medicine of the present invention to treat, was almost recovered after application surrounding.
(3) Wang, female, 37 years old, white collar, came off duty to ride when electric motor car is gone home and meets traffic accident fracture of lower leg, after resetting, use Chinese medicine of the present invention to treat, can lean on and turn working, be almost recovered after application surrounding after taking 9 days.
(4) Zhang, man, 20 years old, university students.The foot sprain when athletic meeting is competed, uses Chinese medicine of the present invention to treat, and after taking one day, pain weakens obviously, sprains position and subsides a swelling completely, fully recover after taking 7 days after 5 days.
(5) Qin, man, 67 years old, peasant, there is ulcer in shank surface, checks and learn trouble sticky sore leg, use Chinese medicine of the present invention to treat through doctor, and ulcer wound surface starts incrustation two days later, takes and that is returns to one's perfect health after one month a course for the treatment of.