CN107802814A - Chinese medicine composition and its manufactured plaster and preparation method - Google Patents
Chinese medicine composition and its manufactured plaster and preparation method Download PDFInfo
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/237—Notopterygium
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
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- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A61K36/185—Magnoliopsida (dicotyledons)
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Abstract
The invention provides a kind of Chinese medicine composition and its manufactured plaster and preparation method, it is related to traditional Chinese medicine technology technical field, the Chinese medicine composition mainly includes following components:Impatientis, radix rehmanniae recen, Radix Angelicae Sinensis, rhizoma arisaematis, monkshood, radix aconiti agrestis, notopterygium root, levisticum, frankincense, myrrh, rhizoma zingiberis, Chinese cassia tree, cloves, root of Chinese clematis, Common St.Paulswort Herbs, golden cypress, Chinese honey locust (fruit), corydalis tuber, calamine, alumen, native copper, hydrargyrum chloratum compositum, Soil unit and catechu, lack the effectively Chinese medicine preparation for the treatment of osteopathy and plaster performance pharmacodynamic feature present in prior art lowly and easily to quick technical problem to alleviate, reach the technique effect for curing bone class disease.
Description
Technical field
The present invention relates to traditional Chinese medicine technology technical field, more particularly, to a kind of Chinese medicine composition and its manufactured plaster and system
Preparation Method.
Background technology
Osteopathy, generally comprise rheumatic arthritis, rheumatoid arthritis, degenerative arthritis, cervical spondylopathy, lumbar vertebra disease,
The disease such as scapulohumeral periarthritis and curing hyperosteogeny.Patient is difficult to cure if ill, and expectant treatment includes traction, massage, acupuncture, reason
The methods for the treatment of, slowly effect and can not thoroughly it effect a radical cure, operative treatment is quick, can be with rapid relief of symptoms, but risk and pair
Effect is higher.
Plaster is five big pharmaceutical dosage form of China's traditional Chinese medicine:One of ball, scattered, cream, pellet, soup, it is each to be widely used in treatment
Kind disease, it is particularly applied to the damage of muscles and bones class and disease.General plaster includes two parts of matrix and medicine, is managed with Traditional Chinese Medicine
By to instruct, medicine is dissolved or mixed in appropriate matrix, spreads onto on paper, cloth or skin, is affixed on affected part or collaterals of human cave
On position, medicine into blood circulation, produces local action or general action, it is stagnant to play its network that stimulates the menstrual flow away, row by Transdermal absorption
Stasis eliminatings, deep, wind dispelling cold dispelling of having one's ideas straightened out, Eradicates wet function, so as to reach the purpose for the treatment of disease.
Traditional black plaster has that environmental pollution is big, and when high temperature frying concentrates, active ingredient goes to pot Chinese medicine;The black cream of tradition
Medicine main component is that red lead (lead orthoplumbate) is as harmful in used for a long time, in-convenience in use, and skin should not clean,
Therefore, develop a kind of external application Chinese medicine formula that can effectively treat osteopathy and external application Chinese medicine can be made to give full play to its pharmacological action
And the plaster having no toxic side effect is that have the problem of to be solved at present.
In view of this, it is special to propose the present invention.
The content of the invention
The first object of the present invention is to provide a kind of Chinese medicine composition, lacked with alleviating present in prior art effectively
Treat the technical problem of the Chinese medicine preparation of osteopathy.
The second object of the present invention is in providing a kind of described Chinese medicine composition in the medicine for preparing treatment osteopathy
Using to alleviate the skill for lacking the effectively Chinese medicine preparation for the treatment of osteopathy present in prior art in the medicine of external curing osteopathy
Art problem.
The third object of the present invention is to provide a kind of plaster for including above-mentioned Chinese medicine composition, to alleviate in the prior art
The existing technical problem for lacking the effectively plaster for the treatment of osteopathy.
The fourth object of the present invention is to provide a kind of preparation method of above-mentioned plaster, to alleviate present in prior art
Plaster plays pharmacodynamic feature lowly and is easily caused the technical problem of allergy.
A kind of Chinese medicine composition, count mainly includes following component in parts by weight:30~50 parts of Impatientis, radix rehmanniae recen 20~
35 parts, 15~35 parts of Radix Angelicae Sinensis, 12~30 parts of rhizoma arisaematis, 15~25 parts of monkshood, 15~25 parts of radix aconiti agrestis, 10~25 parts of notopterygium root, levisticum
10~25 parts, 10~25 parts of frankincense, 10~25 parts of myrrh, 10~25 parts of rhizoma zingiberis, 10~25 parts of Chinese cassia tree, 10~25 parts of cloves, prestige
20~35 parts of the Fen, Common St.Paulswort Herbs of medicine xiaolingxian 30~50,18~35 parts of golden cypress, 18~35 parts of Chinese honey locust (fruit), 20~30 parts of corydalis tuber, calamine
20~30 parts of 5~15 parts, 5~15 parts of alumen, 5~10 parts of native copper, 5~10 parts of hydrargyrum chloratum compositum, 15~25 parts of Soil unit and catechu.
Further, the Chinese medicine composition is counted in parts by weight mainly includes following component:42~48 parts of Impatientis, life
28~32 parts of glutinous rehmannia, 25~32 parts of Radix Angelicae Sinensis, 18~28 parts of rhizoma arisaematis, 18~22 parts of monkshood, 18~22 parts of radix aconiti agrestis, notopterygium root 18~25
Part, 18~22 parts of levisticum, 18~22 parts of frankincense, 15~22 parts of myrrh, 10~20 parts of rhizoma zingiberis, 12~18 parts of Chinese cassia tree, cloves 12~
18 parts, 27~32 parts of the Fen, Common St.Paulswort Herbs of the root of Chinese clematis 40~48,25~32 parts of golden cypress, 25~32 parts of Chinese honey locust (fruit), corydalis tuber 22~28
Part, 8~12 parts of calamine, 8~12 parts of alumen, 7~9 parts of native copper, 7~9 parts of hydrargyrum chloratum compositum, 18~22 parts of Soil unit and catechu 22~
28 parts.
Further, the Chinese medicine composition is counted in parts by weight mainly includes following component:45 parts of Impatientis, radix rehmanniae recen
30 parts, 30 parts of Radix Angelicae Sinensis, 25 parts of rhizoma arisaematis, 20 parts of monkshood, 20 parts of radix aconiti agrestis, 20 parts of notopterygium root, 20 parts of levisticum, 20 parts of frankincense, myrrh 20
Part, 15 parts of rhizoma zingiberis, 15 parts of Chinese cassia tree, 15 parts of cloves, 30 parts of the Fen, Common St.Paulswort Herbs of the root of Chinese clematis 45,30 parts of golden cypress, 30 parts of Chinese honey locust (fruit), prolong recklessly
25 parts of 25 parts of rope, 10 parts of calamine, 10 parts of alumen, 8 parts of native copper, 8 parts of hydrargyrum chloratum compositum, 20 parts of Soil unit and catechu.
A kind of application of above-mentioned Chinese medicine composition in the medicine for preparing treatment osteopathy.
A kind of plaster, include above-mentioned Chinese medicine composition.
A kind of preparation method of above-mentioned plaster, it is main to include mixing with matrix after above-mentioned Chinese medicine composition is crushed
Uniformly, the step of spreading onto carrier.
Further, above-mentioned preparation method also include above-mentioned Chinese medicine composition is grouped as follows, after crushing according to
The step of secondary addition matrix, packet mode is as follows:
Preferably, the component of the A groups mixes after being crushed to 120~220 mesh with matrix;
Preferably, the component of the B groups is crushed to 35~100 mesh, adds solvent soaking 150~168 hours, will be described molten
Mixed after agent evaporation with matrix.
Further, the matrix and the ratio of Chinese medicine composition mixing are 1:1.1~1:1.6.Further, institute
It is medical hot melt adhesive to state matrix;
Further, the preparation method also includes adding the step of bleeding agent stirs and evenly mixs in the matrix.
Chinese medicine composition provided by the invention includes a variety of rheumatism classes and softening hard masses dredging collateral medicine, Wen Litong numbness, awakening consciousness,
The promoting blood circulation Eradicates stasis of bloods, softening and resolving hard mass, tonifying Qi and blood.Described Chinese medicine composition provided by the invention is in the medicine for preparing treatment osteopathy
Application, improve treatment osteopathy topical drug the effect of.The medicine provided by the invention for including above-mentioned Chinese medicine composition,
Can effectively alleviate chill it is wet caused by rheumatism with cause because of malpractice fever and chills mutually win various osteoarthropathy extremely.This
The plaster for including above-mentioned Chinese medicine composition provided, Wen Litong numbness, awakening consciousness, the Eradicates stasis of bloods of invigorating blood circulation, softening and resolving hard mass, help gas are provided
Blood, naturally without sulphur, lead, mercury, gone directly focus through skin, and and blood circulation, penetration is strong, and transdermal to penetrate multiplication, curative effect is fast, makes
With safe ready, can rapid recovery rheumatic arthritis, more analgesic bone class diseases such as spondylodynia and lumbar vertebra disease.It is provided by the invention
The preparation method of above-mentioned plaster, is mixed after Chinese medicine material is crushed with matrix, and soft viscosity is suitable, and winter does not ftracture, and summer is not
Seepage flow, drug effect is given full play to, processing step is simple, is easy to large-scale production.
Embodiment
Technical scheme is clearly and completely described below in conjunction with embodiment, it is clear that described reality
It is part of the embodiment of the present invention to apply example, rather than whole embodiments.Based on the embodiment in the present invention, the common skill in this area
The every other embodiment that art personnel are obtained under the premise of creative work is not made, belong to the model that the present invention protects
Enclose.
Chinese medicine composition provided by the invention is according to theory of traditional Chinese medical science, diagnosis and treatment based on an overall analysis of the illness and the patient's condition, it then follows the elite of successive dynasties external treatment with Chinese medicine, knot
Most of case histories of modern age patient are closed, this patch uses the characteristic of each taste Chinese medicine, Wen Litong numbness fierce with its natural disposition, and fragrance leads to
Key, the Eradicates stasis of bloods of invigorating blood circulation, softening and resolving hard mass, tonifying Qi and blood, naturally the Chinese medicine scientific composition without sulphur, lead and mercury.
In the Chinese medicine composition, the wet class medicine of evacuate pathogenic wind has:Monkshood, radix aconiti agrestis, levisticum, notopterygium root, rhizoma zingiberis, Chinese cassia tree, cloves, Wheeling
Xian , Common St.Paulswort Herbs;Promoting blood circulation and removing blood stasis, softening hard masses dredging collateral medicine has:Impatientis, Radix Angelicae Sinensis, rhizoma arisaematis, Chinese honey locust (fruit), radix rehmanniae recen, frankincense, myrrh;
Eliminating dampness, desensitization class medicine have:Golden cypress, alumen, calamine , Common St.Paulswort Herbs;In order that Bones and joints degenerative lesion and disc herniation, swollen
Go out and preferably recovered, its medicine has:Native copper, Soil unit;To alleviating Bones and joints purulent lesion, its medicine has hydrargyrum chloratum compositum,
Catechu, golden cypress.
Wherein, one feature of this Chinese medicine composition is to treat the wet caused rheumatism of chill and Yin Zhi using Impatientis for main ingredient
Treat it is improper and cause fever and chills mutually win various osteoarthropathy extremely.Contain flavone compound in Impatientis, naphthoquinones, cumarin and
Black alcohols chemical composition, have antimycotic, suppression bacterium, anti-inflammatory and antalgic, antiallergy, rush transdermal and suppress the medicines of a variety of cancer cells
Reason acts on.
Chinese medicine composition provided by the invention, count mainly includes following component in parts by weight:30~50 parts of Impatientis, life
20~35 parts of glutinous rehmannia, 15~35 parts of Radix Angelicae Sinensis, 12~30 parts of rhizoma arisaematis, 15~25 parts of monkshood, 15~25 parts of radix aconiti agrestis, notopterygium root 10~25
Part, 10~25 parts of levisticum, 10~25 parts of frankincense, 10~25 parts of myrrh, 10~25 parts of rhizoma zingiberis, 10~25 parts of Chinese cassia tree, cloves 10~
25 parts, 20~35 parts of the Fen, Common St.Paulswort Herbs of the root of Chinese clematis 30~50,18~35 parts of golden cypress, 18~35 parts of Chinese honey locust (fruit), corydalis tuber 20~30
Part, 5~15 parts of calamine, 5~15 parts of alumen, 5~10 parts of native copper, 5~10 parts of hydrargyrum chloratum compositum, 15~25 parts of Soil unit and catechu 20
~30 parts.
Impatientis:Bitter, it is warm-natured;Wind-dispelling, invigorate blood circulation, subside a swelling, analgesic;Available for treatment articular rheumatic pain, traumatic injury, scrofula
Scrofula ulcer, furunculosis.
In an optional embodiment, the parts by weight of Impatientis for example can be but be not restricted to 30 parts, 31 parts,
32 parts, 33 parts, 34 parts, 35 parts, 36 parts, 37 parts, 38 parts, 39 parts, 40 parts, 41 parts, 42 parts, 43 parts, 44 parts, 45 parts, 46 parts, 47
Part, 48 parts, 49 parts or 50 parts.
Radix rehmanniae recen:It is sweet, it is cold in nature;The thoughts of returning home, liver and kidney channel;Clearing heat and cooling blood, nourishing Yin and promoting production of body fluid;Enter ying blood, epidemic heat syndrome hair for heat
Spot, hematemesis and epistaxis, consumption of YIN caused by febrile disease, the deep red polydipsia of tongue, Tianjin hinder constipation, fever due to yin deficiency, hectic fever due to yin labor heat, Heat Diabetes.
In an optional embodiment, the parts by weight of radix rehmanniae recen for example can be but be not restricted to 20 parts, 21 parts,
22 parts, 23 parts, 24 parts, 25 parts, 26 parts, 27 parts, 28 parts, 29 parts, 30 parts, 31 parts, 32 parts, 33 parts, 34 parts or 35 parts.
Radix Angelicae Sinensis:It is sweet, pungent, it is warm-natured;Return liver, the heart, the spleen channel;Replenishing and activating blood, menstruction regulating and pain relieving, relax bowel;Withered for the deficiency of blood
Huang, dizziness palpitaition, irregular menstruation, closed dysmenorrhea, asthenia cold abdominalgia, arthralgia pain due to rheumatism, injury from falling down, ulcer sores, dry constipation of intestines.
In an optional embodiment, the parts by weight of Radix Angelicae Sinensis for example can be but be not restricted to 15 parts, 16 parts, 17
Part, 18 parts, 19 parts, 20 parts, 21 parts, 22 parts, 23 parts, 24 parts, 25 parts, 26 parts, 27 parts, 28 parts, 29 parts, 30 parts, 31 parts, 32
Part, 33 parts, 34 parts or 35 parts.
In one preferred embodiment, above-mentioned Radix Angelicae Sinensis uses Radix Angelicae Sinensis tail.
Rhizoma arisaematis:It is bitter, pungent, it is warm-natured;Return lung, liver, the spleen channel;It is eliminating dampness and eliminating phlegm, expelling wind and relieving convulsion, mass dissipating and swelling eliminating;For stupid phlegm
Carbuncle swells are controlled in cough, anemophlegmatic vertigo, heap soil or fertilizer over and around the roots of apoplexy phlegm, deviation of the eye and mouth, hemiplegia, leprosy epilepsy, infantile convulsion, lockjaw, external application, and snakeworm stings
Wound.
In an optional embodiment, the parts by weight of rhizoma arisaematis for example can be but be not restricted to 12 parts, 13 parts,
14 parts, 15 parts, 16 parts, 17 parts, 18 parts, 19 parts, 20 parts, 21 parts, 22 parts, 23 parts, 24 parts, 25 parts, 26 parts, 27 parts, 28 parts, 29
Part or 30 parts.
Monkshood:Acrid flavour, hardship, property heat are poisonous;The thoughts of returning home, liver,kidney,spleen warp;Dispelling wind and eliminating dampness, antalgic;It is wet for chill
Numbness, arthralgia, trusted subordinate's crymodynia, cold hernia is had a pain and narcotic analgesic.
In an optional embodiment, the parts by weight of monkshood for example can be but be not restricted to 15 parts, 16 parts, 17
Part, 18 parts, 19 parts, 20 parts, 21 parts, 22 parts, 23 parts, 24 parts or 25 parts.
Radix aconiti agrestis:Acrid flavour, hardship, property heat are poisonous;The thoughts of returning home, liver,kidney,spleen warp;Dispelling wind and eliminating dampness, antalgic;It is wet for chill
Numbness, arthralgia, trusted subordinate's crymodynia, cold hernia is had a pain and narcotic analgesic.
In an optional embodiment, the parts by weight of radix aconiti agrestis for example can be but be not restricted to 15 parts, 16 parts, 17
Part, 18 parts, 19 parts, 20 parts, 21 parts, 22 parts, 23 parts, 24 parts or 25 parts.
Notopterygium root:Acrid flavour, hardship, it is warm-natured;Return bladder, kidney channel;Relieving exterior syndrome and dispelling cold, dispelling wind and eliminating dampness, analgesic;For anemofrigid cold, head
Pain Xiang Qiang, arthralgia pain due to rheumatism, aching pain in shoulder and back.
In an optional embodiment, the parts by weight of notopterygium root for example can be but be not restricted to 10 parts, 11 parts, 12
Part, 13 parts, 14 parts, 15 parts, 16 parts, 17 parts, 18 parts, 19 parts, 20 parts, 21 parts, 22 parts, 23 parts, 24 parts or 25 parts.
Levisticum:Acrid flavour, hardship, slightly warm in nature;Return kidney, bladder warp;Dispelling wind and eliminating dampness, numbness relieving and pain relieving;For wind-cold-dampness arthralgia, waist and knee pain
Bitterly, few the moon volt wind headache, chill hold wet headache under the arm.
In an optional embodiment, the parts by weight of levisticum for example can be but be not restricted to 10 parts, 11 parts, 12
Part, 13 parts, 14 parts, 15 parts, 16 parts, 17 parts, 18 parts, 19 parts, 20 parts, 21 parts, 22 parts, 23 parts, 24 parts or 25 parts
Frankincense:Acrid flavour, hardship, it is warm-natured;The thoughts of returning home, liver, the spleen channel;Promoting blood circulation analgesic therapy, detumescence and promoting granulation;For chest impediment and cardialgia, pain of gastric cavity
Bitterly, dysmenorrhoea Amenorrhea, postpartum stasis , Disorder lump in the abdomen is suffered from abdominal pain, arthralgia pain due to rheumatism, muscle arteries and veins contraction, traumatic injury, carbuncle swells sore.
In an optional embodiment, the parts by weight of frankincense for example can be but be not restricted to 10 parts, 11 parts, 12
Part, 13 parts, 14 parts, 15 parts, 16 parts, 17 parts, 18 parts, 19 parts, 20 parts, 21 parts, 22 parts, 23 parts, 24 parts or 25 parts.
Myrrh:Acrid flavour, hardship, it is warm-natured;The thoughts of returning home, liver, the spleen channel;Promoting blood circulation analgesic therapy, detumescence and promoting granulation;For chest impediment and cardialgia, pain of gastric cavity
Bitterly, dysmenorrhoea Amenorrhea, postpartum stasis , Disorder lump in the abdomen is suffered from abdominal pain, arthralgia pain due to rheumatism, muscle arteries and veins contraction, traumatic injury, carbuncle swells sore.
In an optional embodiment, the parts by weight of myrrh for example can be but be not restricted to 10 parts, 11 parts, 12
Part, 13 parts, 14 parts, 15 parts, 16 parts, 17 parts, 18 parts, 19 parts, 20 parts, 21 parts, 22 parts, 23 parts, 24 parts or 25 parts.
Rhizoma zingiberis:Acrid flavour, property heat;Returns spleen, stomach, kidney, the heart, lung channel;Warming spleen and stomach for dispelling cold, Back to Yang Tongmai, Wenfei of drink;For gastral cavity abdomen
Crymodynia, vomiting and diarrhea, cold weak pulse of limb, cold drink are breathed with cough, and especially have good therapeutic action to the disease of cold-dampness.
Rhizoma arisaematis, monkshood and radix aconiti agrestis all use the crude drug without processing in the present invention, and crude drug toxic side effect is big, but reduce
The loss of effective ingredient, makes the active ingredient of medicine be fully utilized and play, makes the Chinese medicine in concocting process
Composition plays stronger drug effect.The present invention alleviates the toxic side effect of the crude drug without processing by adding rhizoma zingiberis, so as to subtract
The side effect of the Chinese medicine composition is lacked, the safety of medication is advantageously ensure that while illness is alleviated.
In an optional embodiment, the parts by weight of rhizoma zingiberis for example can be but be not restricted to 10 parts, 11 parts, 12
Part, 13 parts, 14 parts, 15 parts, 16 parts, 17 parts, 18 parts, 19 parts, 20 parts, 21 parts, 22 parts, 23 parts, 24 parts or 25 parts.
Chinese cassia tree:Acrid flavour, sweet, extremely hot in nature;Return kidney, spleen, the heart, Liver Channel;Mends fire supporing yang, guiding fire to origin, eliminating cold to stop pain, temperature are stimulated the menstrual flow
Arteries and veins;For positive fistula Gong Leng, waist and knee crymodynia, deficiency of the kidney and dyspnea, deficient yang with upper manifestation, dizziness hot eyes, trusted subordinate's crymodynia, cold of insufficiency type vomiting and diarrhea, cold hernia abdomen
Bitterly, dysmenorrhoea Amenorrhea.
In an optional embodiment, the parts by weight of Chinese cassia tree for example can be but be not restricted to 10 parts, 11 parts, 12
Part, 13 parts, 14 parts, 15 parts, 16 parts, 17 parts, 18 parts, 19 parts, 20 parts, 21 parts, 22 parts, 23 parts, 24 parts or 25 parts.
Cloves:Acrid flavour, it is warm-natured;Returns spleen, stomach, lung, kidney channel;Middle benefit gas drop is inverse, tonifies the kidney and support yang;For deficiency-cold in spleen and stomach, hiccup is vomitted
Tell, deficiency of food is vomited and diarrhoea, trusted subordinate's crymodynia, impotence due to deficiency of the kidney.
In an optional embodiment, the parts by weight of cloves for example can be but be not restricted to 10 parts, 11 parts, 12
Part, 13 parts, 14 parts, 15 parts, 16 parts, 17 parts, 18 parts, 19 parts, 20 parts, 21 parts, 22 parts, 23 parts, 24 parts or 25 parts.
The root of Chinese clematis:It is acrid flavour, salty, it is warm-natured;Return bladder warp;Wind-damp dispelling, degrading the channel;For arthralgia pain due to rheumatism, extremity numbness, tendon and vessel
Contraction, joint stuffiness.
In an optional embodiment, the parts by weight of the root of Chinese clematis for example can be but be not restricted to 30 parts, 31 parts,
32 parts, 33 parts, 34 parts, 35 parts, 36 parts, 37 parts, 38 parts, 39 parts, 40 parts, 41 parts, 42 parts, 43 parts, 44 parts, 45 parts, 46 parts, 47
Part, 48 parts, 49 parts or 50 parts.
Common St.Paulswort Herb:Acrid flavour, hardship, it is cold in nature;Return liver and kidney channel;Wind-damp dispelling, sharp joint, removing toxic substances;For arthralgia pain due to rheumatism, muscles and bones without
Power, soreness and weakness of waist and knees, quadriplegia, hemiplegia, rubella wet sore.In the parts by weight of an optional embodiment Zhong , Common St.Paulswort Herb
Numerical example such as can be but be not restricted to 20 parts, 21 parts, 22 parts, 23 parts, 24 parts, 25 parts, 26 parts, 27 parts, 28 parts, 29 parts, 30 parts,
31 parts, 32 parts, 33 parts, 34 parts or 35 parts.
Golden cypress:Bitter, it is cold in nature;Return kidney, bladder warp;Heat-clearing and damp-drying drug, purging intense heat, except steaming, detoxification sore treatment;It is yellow for damp-heat dysentery
Subcutaneous ulcer urine is red, with lower pruritus vulvae, puckery pain of heat gonorrhea, tinea pedis Wei lame, hectic fever due to yin labor heat, night sweat, seminal emission, sore swollen toxin, eczema wet sore.Stir-baked CORTEX PHELLODENDRI with salt solution
Nourishing Yin and falling fire.For fire excess from yin deficiency, night sweat hectic fever due to yin.
In an optional embodiment, the parts by weight of golden cypress for example can be but be not restricted to 18 parts, 19 parts, 20
Part, 21 parts, 22 parts, 23 parts, 24 parts, 25 parts, 26 parts, 27 parts, 28 parts, 29 parts, 30 parts, 31 parts, 32 parts, 33 parts, 34 parts or 35
Part.
Chinese honey locust (fruit):It is acrid flavour, salty, it is warm-natured;Return lung, large intestine channel;Eliminating the phlegm is had one's ideas straightened out, mass dissipating and swelling eliminating;For apoplexy lockjaw, stupor is not
Wake up, epilepsy phlegm is contained, and pass key is obstructed, and the resistance of larynx numbness phlegm, stupid asthma due to excessive phlegm cough, expectoration is not well, dry feces;Controlling outward carbuncle swells.
In an optional embodiment, the parts by weight of Chinese honey locust (fruit) for example can be but be not restricted to 18 parts, 19 parts,
20 parts, 21 parts, 22 parts, 23 parts, 24 parts, 25 parts, 26 parts, 27 parts, 28 parts, 29 parts, 30 parts, 31 parts, 32 parts, 33 parts, 34 parts or
35 parts.
Corydalis tuber:It is acrid flavour, hardship, warm-natured;Return liver, the spleen channel;Promoting blood circulation, promoting the circulation of qi, analgesic;For chest side of body, epigastric pain, the obstruction of qi in the chest heart
Bitterly, closed dysmenorrhea, postpartum stasis, tumbling and swelling.
In an optional embodiment, the parts by weight of corydalis tuber for example can be but be not restricted to 20 parts, 21 parts,
22 parts, 23 parts, 24 parts, 25 parts, 26 parts, 27 parts, 28 parts, 29 parts or 30 parts.
Calamine:It is sweet, it is mild-natured;Return liver, the spleen channel;Detoxify removing nebula, the antipruritic sore of hygroscopic;For red eye, swell pain, eyelid
String is red rotten, and pterygium is pterygium, and unhealing ulcer, pus is dripping, wet sore itch.
In an optional embodiment, the parts by weight of calamine for example can be but be not restricted to 5 parts, 6 parts, 7
Part, 8 parts, 9 parts, 10 parts, 11 parts, 12 parts, 13 parts, 14 parts or 15 parts.
Alumen:It is sour, puckery, it is cold in nature;Return lung, spleen, liver, large intestine channel;External application removing toxic substances desinsection, eliminating dampness is antipruritic, for oral administration to stop
Rush down, dispel wind phlegm.
In an optional embodiment, the parts by weight of alumen for example can be but be not restricted to 5 parts, 6 parts, 7 parts,
8 parts, 9 parts, 10 parts, 11 parts, 12 parts, 13 parts, 14 parts or 15 parts.
Native copper:Acrid flavour, it is mild-natured;Return liver warp;Blood stasis removing analgesic, reunion of fractured tendons and bones;For traumatic injury, injured bone, the stasis of blood swells
Pain.
In an optional embodiment, the parts by weight of native copper for example can be but be not restricted to 5 parts, 6 parts, 7
Part, 8 parts, 9 parts or 10 parts.
Hydrargyrum chloratum compositum:Draw out pus by applying a plaster to the affected part detumescence, remove rotten desinsection;Cure mainly mumps, scrofula, bone and bone nodule core, skin
Skin tumour, infectious granuloma, proliferation of mammary gland etc..
In an optional embodiment, the parts by weight of hydrargyrum chloratum compositum for example can be but be not restricted to 5 parts, 6 parts, 7
Part, 8 parts, 9 parts or 10 parts.
Soil unit:Taste is salty, cold in nature;Return liver warp;Broken stasis of blood blood, continuous muscles and bones;For injured bone, blood stasis closed, abdominal mass lump in the abdomen.
In an optional embodiment, the parts by weight of Soil unit for example can be but be not restricted to 15 parts, 16 parts, 17
Part, 18 parts, 19 parts, 20 parts, 21 parts, 22 parts, 23 parts, 24 parts or 25 parts.
Catechu:Bitter, puckery, cold nature;Return lung, the heart channel of Hang-Shaoyin;Promoting blood circulation and stopping pain, hemostasia and promoting granulation, hygroscopic sore, clearing lung and eliminating phlegm;With
Do not held back in the pain of injury caused by falling and tumbling, traumatism and bleeding, haematemesis brain blood, sore, eczema, wet sore, cough with lung heat.
In an optional embodiment, the parts by weight of catechu for example can be but be not restricted to 20 parts, 21 parts, 22
Part, 23 parts, 24 parts, 25 parts, 26 parts, 27 parts, 28 parts, 29 parts or 30 parts.
Skin need to be overlying on when being acted on due to plaster for a long time, easily causes allergy and eczema, therefore add in the present embodiment
Enter the component with hygroscopic and antiallergy effect:Common St.Paulswort Herb, golden cypress, alumen, calamine and catechu, it is used in plaster to affected part
Hygroscopic and antiallergy, avoid and be overlying on the uncomfortable reaction such as caused eczema or allergy on skin for a long time in plaster, improve this
The comfort level of plaster and applicable crowd's scope in embodiment.
In one preferred embodiment, above-mentioned Chinese medicine composition is counted in parts by weight mainly includes following component:Phoenix
45 parts of celestial grass, 30 parts of radix rehmanniae recen, 30 parts of Radix Angelicae Sinensis, 25 parts of rhizoma arisaematis, 20 parts of monkshood, 20 parts of radix aconiti agrestis, 20 parts of notopterygium root, 20 parts of levisticum,
20 parts of frankincense, 20 parts of myrrh, 15 parts of rhizoma zingiberis, 15 parts of Chinese cassia tree, 15 parts of cloves, 30 parts of the Fen, Common St.Paulswort Herbs of the root of Chinese clematis 45,30 parts of golden cypress,
30 parts of Chinese honey locust (fruit), 25 parts of corydalis tuber, 10 parts of calamine, 10 parts of alumen, 8 parts of native copper, 8 parts of hydrargyrum chloratum compositum, 20 parts of Soil unit and catechu
25 parts.
Application of the Chinese medicine composition provided by the invention in the medicine for preparing treatment osteopathy.The Chinese medicine composition improves
The effect for the treatment of the topical drug of osteopathy.
Preferably, the osteopathy mainly includes treating rheumatic ostealgia, cervical spondylopathy, waist dish outstanding, osteoproliferation, rheumatism joint
Scorching or injury from falling down.
A kind of plaster provided by the invention, is made up of above-mentioned Chinese medicine composition.
The existing popular patch of in the market has two big defects, one:Be attached to after affected part it is scorching hot unbearably;Second, very itch and go out
Existing macula.Traditional black plaster main component is red lead, and such as long-time uses harmful, in-convenience in use, skin should not be clear
Wash.This patch softness viscosity is suitable, and winter does not ftracture, and summer, seepage flow, Qing Dynasty doctor Wu Qian did not existed《Yizong Jinjian》It is proposed, " cream
Medicine when with softness moisten, by means of wet to have one's ideas straightened out, dry then medicine gas does not enter, the anti-hardship for adding arrested anxious " warning.This plaster is with modern medical rubber
Glue is base-material, substitutes with vegetable oil yellow lead matrix plaster barrier and toxicity, the property of medicine is entered space between skin and muscles from pore, stimulate the menstrual flow used network or
It is carried, reaches unobstructed qi and blood, gentle negative and positive, dredges the effects of internal organs.
The preparation method of plaster provided by the invention, it is main to include mixing with matrix after above-mentioned Chinese medicine composition is crushed
Stir, the step of spreading onto carrier.
In an optional embodiment, above-mentioned preparation method is also included above-mentioned Chinese medicine composition as follows
Packet, the step of sequentially adding matrix after crushing, packet mode is as follows:
A groups:Impatientis, radix rehmanniae recen, Radix Angelicae Sinensis, rhizoma arisaematis, monkshood, radix aconiti agrestis, frankincense, myrrh, rhizoma zingiberis, Chinese cassia tree, cloves, big soap
Angle, corydalis tuber and catechu;
B groups:Golden cypress, root of Chinese clematis, Common St.Paulswort Herbs, notopterygium root and levisticum;
C groups:Alumen, calamine, native copper and hydrargyrum chloratum compositum.
In one preferred embodiment, the component of above-mentioned A groups be crushed to for example can be but be not restricted to 120 mesh,
140 mesh, 170 mesh, 200 mesh or 220 mesh.
In a preferred embodiment, the component of above-mentioned A groups is crushed to 170 mesh.
Above-mentioned traditional Chinese medicinal components are crushed to micron order, can destroy histocyte wall construction, obtain required material characteristic.
In one preferred embodiment, the component of above-mentioned B groups is crushed to 35~100 mesh, add solvent soaking 150~
168 hours, mixed after concentration with medical hot melt adhesive.
In one preferred embodiment, the component of above-mentioned B groups, which is crushed to, for example can be but be not restricted to 35 mesh, 40
Mesh, 45 mesh, 50 mesh, 60 mesh, 70 mesh, 80 mesh or 100 mesh.
In a preferred embodiment, the component of above-mentioned B groups is crushed to 50 mesh.
In one preferred embodiment, soak time for example can be but be not restricted to 150,152,155,157,
160th, 165 or 168 hours.
In a preferred embodiment, soak time is 160 hours.
In one preferred embodiment, above-mentioned solvent is absolute ethyl alcohol.
In one preferred embodiment, above-mentioned solvent, which is evaporated in water-bath, is heated to solvent and evaporates.
In advance by the active ingredient dissolution in Chinese medicine the active ingredient in medicine can be made to be more easy to lead to using organic solvent ethanol
Cross skin and penetrate into body.
In an optional embodiment, above-mentioned matrix and above-mentioned Chinese medicine composition mixing ratio for example can be but
It is not restricted to 1:1.1、1:1.2、1:1.25、1:1.3、1:1.4、1:1.5 or 1:1.6.
In a preferred embodiment, the ratio of above-mentioned matrix and the mixing of above-mentioned Chinese medicine composition is 1:1.3.
By optimizing the ratio of matrix and Chinese medicine composition, the drug effect of plaster can be improved and keep the softness of plaster simultaneously
Degree and comfort level.
In an optional embodiment, above-mentioned matrix mainly includes medical hot melt adhesive.
In an optional embodiment, above-mentioned preparation method also includes addition bleeding agent in above-mentioned matrix and stirred and evenly mixed
The step of.
In an optional embodiment, as mass fraction, added in above-mentioned medical hot melt adhesive for example can be but
1.5 ‰, 1.6 ‰, 1.7 ‰, 1.8 ‰, 1.9 ‰, 2.0 ‰, 2.1 ‰, 2.2 ‰, 2.3 ‰, 2.4 ‰ or 2.5 ‰ are not restricted to ooze
Saturating agent.
In one preferred embodiment, as mass fraction, 1.6 ‰ infiltration is added in above-mentioned medical hot melt adhesive
Agent.
In a preferred embodiment, above-mentioned bleeding agent is azone.
Azone can be used as bleeding agent, for all kinds of creams and/or external used medicine in cosmetics, can promote in medicine it is effective into
Divide and penetrate into skin, strengthen drug effect.
In one preferred embodiment, above-mentioned carrier is medical proof fabric.
The preparation method combination modern medicine principle of above-mentioned plaster, medicine use superfine communication technique, soaked in absolute ethyl alcohol,
Low temperature concentration makes to make full use of containing volatile oil, fat oil, alkaloid, aldehyde, acetic acid esters, glucoside, calcium class material, retains former Chinese medicine life
State active ingredient, gone directly focus through skin, and and blood circulation, penetration is strong, and transdermal to penetrate multiplication, curative effect is fast, safe to use
It is convenient.
For the clearer explanation present invention, with reference to preferred embodiment, the present invention is described further.
Embodiment 1
A kind of Chinese medicine composition is present embodiments provided, meter includes following component in parts by weight:30 parts of Impatientis, the dried rhizome of rehmannia
It is yellow 35 parts, 15 parts of Radix Angelicae Sinensis tail, 30 parts of rhizoma arisaematis, 15 parts of monkshood, 25 parts of radix aconiti agrestis, 10 parts of notopterygium root, 25 parts of levisticum, 10 parts of frankincense, do not have
25 parts of medicine, 10 parts of rhizoma zingiberis, 25 parts of Chinese cassia tree, 10 parts of cloves, 20 parts of the Fen , Common St.Paulswort Herbs of the root of Chinese clematis 50,35 parts of golden cypress, 18 parts of Chinese honey locust (fruit),
30 parts of 30 parts of corydalis tuber, 5 parts of calamine, 15 parts of alumen, 5 parts of native copper, 10 parts of hydrargyrum chloratum compositum, 15 parts of Soil unit and catechu.
Embodiment 2
A kind of Chinese medicine composition is present embodiments provided, meter includes following component in parts by weight:50 parts of Impatientis, the dried rhizome of rehmannia
It is yellow 20 parts, 35 parts of Radix Angelicae Sinensis tail, 12 parts of rhizoma arisaematis, 25 parts of monkshood, 15 parts of radix aconiti agrestis, 25 parts of notopterygium root, 10 parts of levisticum, 25 parts of frankincense, do not have
10 parts of medicine, 25 parts of rhizoma zingiberis, 10 parts of Chinese cassia tree, 25 parts of cloves, 35 parts of the Fen , Common St.Paulswort Herbs of the root of Chinese clematis 30,18 parts of golden cypress, 35 parts of Chinese honey locust (fruit),
20 parts of 20 parts of corydalis tuber, 15 parts of calamine, 5 parts of alumen, 10 parts of native copper, 5 parts of hydrargyrum chloratum compositum, 25 parts of Soil unit and catechu.
Embodiment 3
A kind of Chinese medicine composition is present embodiments provided, meter includes following component in parts by weight:42 parts of Impatientis, the dried rhizome of rehmannia
It is yellow 32 parts, 25 parts of Radix Angelicae Sinensis tail, 28 parts of rhizoma arisaematis, 18 parts of monkshood, 22 parts of radix aconiti agrestis, 18 parts of notopterygium root, 22 parts of levisticum, 18 parts of frankincense, do not have
22 parts of medicine, 10 parts of rhizoma zingiberis, 18 parts of Chinese cassia tree, 12 parts of cloves, 27 parts of the Fen , Common St.Paulswort Herbs of the root of Chinese clematis 48,32 parts of golden cypress, 25 parts of Chinese honey locust (fruit),
28 parts of 28 parts of corydalis tuber, 8 parts of calamine, 12 parts of alumen, 7 parts of native copper, 9 parts of hydrargyrum chloratum compositum, 18 parts of Soil unit and catechu.
Embodiment 4
A kind of Chinese medicine composition is present embodiments provided, meter includes following component in parts by weight:48 parts of Impatientis, the dried rhizome of rehmannia
It is yellow 28 parts, 32 parts of Radix Angelicae Sinensis tail, 18 parts of rhizoma arisaematis, 22 parts of monkshood, 18 parts of radix aconiti agrestis, 25 parts of notopterygium root, 18 parts of levisticum, 22 parts of frankincense, do not have
15 parts of medicine, 20 parts of rhizoma zingiberis, 12 parts of Chinese cassia tree, 18 parts of cloves, 32 parts of the Fen , Common St.Paulswort Herbs of the root of Chinese clematis 40,25 parts of golden cypress, 32 parts of Chinese honey locust (fruit),
22 parts of 22 parts of corydalis tuber, 12 parts of calamine, 8 parts of alumen, 9 parts of native copper, 7 parts of hydrargyrum chloratum compositum, 22 parts of Soil unit and catechu.
Embodiment 5
A kind of Chinese medicine composition is present embodiments provided, meter includes following component in parts by weight:45 parts of Impatientis, the dried rhizome of rehmannia
It is yellow 30 parts, 30 parts of Radix Angelicae Sinensis tail, 25 parts of rhizoma arisaematis, 20 parts of monkshood, 20 parts of radix aconiti agrestis, 20 parts of notopterygium root, 20 parts of levisticum, 20 parts of frankincense, do not have
20 parts of medicine, 15 parts of rhizoma zingiberis, 15 parts of Chinese cassia tree, 15 parts of cloves, 30 parts of the Fen , Common St.Paulswort Herbs of the root of Chinese clematis 45,30 parts of golden cypress, 30 parts of Chinese honey locust (fruit),
25 parts of 25 parts of corydalis tuber, 10 parts of calamine, 10 parts of alumen, 8 parts of native copper, 8 parts of hydrargyrum chloratum compositum, 20 parts of Soil unit and catechu.
Embodiment 6
A kind of plaster is present embodiments provided, the Chinese medicine composition for preparing the offer of embodiment 5 by the following method is made, including
Following steps:
(a) by Impatientis, radix rehmanniae recen, Radix Angelicae Sinensis tail, rhizoma arisaematis, monkshood, radix aconiti agrestis, frankincense, myrrh, rhizoma zingiberis, Chinese cassia tree, cloves,
Chinese honey locust (fruit), corydalis tuber and catechu are crushed to 120 mesh.
(b) above-mentioned golden cypress, root of Chinese clematis, Common St.Paulswort Herbs, notopterygium root and levisticum are crushed to 50 mesh, and absolute ethyl alcohol is added after mixing to complete
Full submergence herb powder is advisable, and heating water bath to absolute ethyl alcohol evaporates after soaking 160 hours.
(c) alumen, calamine, native copper, hydrargyrum chloratum compositum mix after crushing.
(d) medical hot melt adhesive is heated, and above-mentioned steps (a), (b) and (c) are sequentially added after adding 1.6 ‰ azone dilution
The ratio of product, medical hot melt adhesive and Chinese medicine composition mixing is 1:1.3.
(e) bonded after spraying cooling with medical proof fabric, the trimmed size cut out is 70mm × 100mm.
Embodiment 7
A kind of plaster is present embodiments provided, the Chinese medicine composition for preparing the offer of embodiment 5 by the following method is made, including
Following steps:
(a) by Impatientis, radix rehmanniae recen, Radix Angelicae Sinensis tail, rhizoma arisaematis, monkshood, radix aconiti agrestis, frankincense, myrrh, rhizoma zingiberis, Chinese cassia tree, cloves,
Chinese honey locust (fruit), corydalis tuber and catechu are crushed to 220 mesh.
(b) above-mentioned golden cypress, root of Chinese clematis, Common St.Paulswort Herbs, notopterygium root and levisticum are crushed to 50 mesh, and absolute ethyl alcohol is added after mixing to complete
Full submergence herb powder is advisable, and heating water bath to absolute ethyl alcohol evaporates after soaking 160 hours.
(c) alumen, calamine, native copper, hydrargyrum chloratum compositum mix after crushing.
(d) medical hot melt adhesive heats, and adds after 4% azone dilution and sequentially adds the production of above-mentioned steps (a), (b) and (c)
The ratio of thing, medical hot melt adhesive and Chinese medicine composition mixing is 1:1.3.
(e) bonded after spraying cooling with medical proof fabric, the trimmed size cut out is 70mm × 100mm.
Embodiment 8
A kind of plaster is present embodiments provided, the Chinese medicine composition for preparing the offer of embodiment 5 by the following method is made, including
Following steps:
(a) by Impatientis, radix rehmanniae recen, Radix Angelicae Sinensis tail, rhizoma arisaematis, monkshood, radix aconiti agrestis, frankincense, myrrh, rhizoma zingiberis, Chinese cassia tree, cloves,
Chinese honey locust (fruit), corydalis tuber and catechu are crushed to 170 mesh.
(b) golden cypress, root of Chinese clematis, Common St.Paulswort Herbs, notopterygium root and levisticum are crushed to 50 mesh, and absolute ethyl alcohol is added after mixing to complete leaching
Do not have herb powder to be advisable, heating water bath to absolute ethyl alcohol evaporates after soaking 160 hours.
(c) alumen, calamine, native copper, hydrargyrum chloratum compositum mix after crushing.
(d) medical hot melt adhesive heats, and adds after 4% azone dilution and sequentially adds the production of above-mentioned steps (a), (b) and (c)
The ratio of thing, medical hot melt adhesive and Chinese medicine composition mixing is 1:1.3.
(e) bonded after spraying cooling with medical proof fabric, the trimmed size cut out is 70mm × 100mm.
Embodiment 9
A kind of plaster is present embodiments provided, the difference with embodiment 8 is golden cypress in step (b), root of Chinese clematis, pig Xian
Grass, notopterygium root and levisticum are crushed to 35 mesh, and absolute ethyl alcohol is added after mixing to be advisable to herb powder is totally submerged, and soaks 160 hours
Heating water bath to absolute ethyl alcohol evaporates afterwards.
Embodiment 10
A kind of plaster is present embodiments provided, the difference with embodiment 8 is golden cypress in step (b), root of Chinese clematis, pig Xian
Grass, notopterygium root and levisticum are crushed to 100 mesh, and absolute ethyl alcohol is added after mixing to be advisable to herb powder is totally submerged, and soaks 160 hours
Heating water bath to absolute ethyl alcohol evaporates afterwards.
Embodiment 11
A kind of plaster is present embodiments provided, the difference with embodiment 8 is after medical hot melt adhesive heating to add in step (d)
Enter 4% azone dilution.
Embodiment 12
A kind of plaster is present embodiments provided, the difference with embodiment 8 is after medical hot melt adhesive heating to add in step (d)
Enter 2.5 ‰ azone dilution.
Embodiment 13
A kind of plaster is present embodiments provided, the difference with embodiment 8 is in step (d) that medical hot melt adhesive heats, and adds
Above-mentioned steps (a), (b) and (c) product, medical hot melt adhesive and Chinese medicine composition are sequentially added after entering 1.6 ‰ azone dilution
The ratio of mixing is 1:1.1.
Embodiment 14
A kind of plaster is present embodiments provided, the difference with embodiment 8 is in step (d) that medical hot melt adhesive heats, and adds
Above-mentioned steps (a), (b) and (c) product, medical hot melt adhesive and Chinese medicine composition are sequentially added after entering 1.6 ‰ azone dilution
The ratio of mixing is 1:1.6.
Embodiment 15
Present embodiments provide a kind of plaster, the difference with embodiment 8 be step (b) golden cypress, root of Chinese clematis, Common St.Paulswort Herbs,
Notopterygium root and levisticum are crushed to 50 mesh, and distilled water is added after mixing to be advisable to herb powder is totally submerged, water-bath after soaking 160 hours
Distilled water is heated to evaporate.
Embodiment 16-19
A kind of plaster is present embodiments provided, is to prepare what is provided comprising embodiment 1-4 with the difference of embodiment 8
Chinese medicine composition.
Comparative example 1
This comparative example provides a kind of Chinese medicine composition, and meter includes following component in parts by weight:20 parts of Impatientis, the dried rhizome of rehmannia
It is yellow 40 parts, 10 parts of Radix Angelicae Sinensis tail, 35 parts of rhizoma arisaematis, 10 parts of monkshood, 30 parts of radix aconiti agrestis, 5 parts of notopterygium root, 30 parts of levisticum, 5 parts of frankincense, myrrh
30 parts, 5 parts of rhizoma zingiberis, 30 parts of Chinese cassia tree, 5 parts of cloves, 10 parts of the Fen , Common St.Paulswort Herbs of the root of Chinese clematis 60,40 parts of golden cypress, 15 parts of Chinese honey locust (fruit), prolong recklessly
40 parts of 35 parts of rope, 3 parts of calamine, 20 parts of alumen, 3 parts of native copper, 15 parts of hydrargyrum chloratum compositum, 10 parts of Soil unit and catechu.
Comparative example 2
This comparative example provides a kind of Chinese medicine composition, and meter includes following component in parts by weight:60 parts of Impatientis, the dried rhizome of rehmannia
It is yellow 10 parts, 40 parts of Radix Angelicae Sinensis tail, 8 parts of rhizoma arisaematis, 30 parts of monkshood, 10 parts of radix aconiti agrestis, 30 parts of notopterygium root, 5 parts of levisticum, 30 parts of frankincense, myrrh 5
Part, 30 parts of rhizoma zingiberis, 5 parts of Chinese cassia tree, 30 parts of cloves, 40 parts of the Fen , Common St.Paulswort Herbs of the root of Chinese clematis 20,15 parts of golden cypress, 40 parts of Chinese honey locust (fruit), corydalis tuber
5 parts, 20 parts of calamine, 3 parts of alumen, 15 parts of native copper, 2 parts of hydrargyrum chloratum compositum, 15 parts of 30 parts of Soil unit and catechu.
Comparative example 3
This comparative example provides a kind of Chinese medicine composition, the difference with embodiment 5 be not contain Impatientis, hydrargyrum chloratum compositum and
Catechu.
Comparative example 4
This comparative example provides a kind of Chinese medicine composition, the difference with embodiment 5 be not contain radix rehmanniae recen, native copper and
Soil unit.
Comparative example 5
This comparative example provides a kind of Chinese medicine composition, the difference with embodiment 5 be not contain Radix Angelicae Sinensis tail, corydalis tuber and
Alumen.
Comparative example 6
This comparative example provides a kind of Chinese medicine composition, the difference with embodiment 5 be not contain rhizoma arisaematis, Chinese honey locust (fruit) and
Calamine.
Comparative example 7
This comparative example provides a kind of Chinese medicine composition, and the difference with embodiment 5 is not containing monkshood, the root of Chinese clematis and Huang
Cypress.
Comparative example 8
This comparative example provides a kind of Chinese medicine composition, and the difference with embodiment 5 is not containing radix aconiti agrestis, cloves He pig Xian
Grass.
Comparative example 9
This comparative example provides a kind of Chinese medicine composition, and the difference with embodiment 5 is not containing notopterygium root, myrrh and meat
Osmanthus.
Comparative example 10
This comparative example provides a kind of Chinese medicine composition, and the difference with embodiment 5 is not containing levisticum, frankincense and done
Ginger.
Comparative example 11
This comparative example provides a kind of plaster, and the Chinese medicine group of the preparation offer of comparative example 1 is with the difference of embodiment 8
Compound.
Comparative example 12
This comparative example provides a kind of plaster, and the Chinese medicine group of the preparation offer of comparative example 2 is with the difference of embodiment 8
Compound.
Effect example 1:
Clinic, which is collected, has treating rheumatic ostealgia patient with sympotoms 560, wherein male 280, women 280, is divided into 28
Group, every group of male patient 10, female patient 10, at 18~65 years old age, the age is randomly assigned.
Patient possesses following symptom:Joint swelling and pain, joint stuffiness, pain increase in intensity under coldness obtains hot, subtracts, morning stiffness, severe patient
Joint deformity.
Treatment method:Affected part is cleaned after the Chinese medicine composition decocting that embodiment 1~5 and comparative example 1~10 are provided, daily
Clean three times, the plaster that embodiment 6~19 and comparative example 1~12 provide is affixed on affected part, pastes within every 24 hours one, blank control group in
Paste the medical proof fabric of formed objects in affected part.
Curative effect determinate standard:Recovery from illness:Clinical symptom disappearance, limb activity freely, are taken care of oneself;It is effective:Clinical symptoms base
This disappearance, freely, life can take care of oneself limb activity substantially;It is invalid:With being not improved before treatment.As a result statistics is as shown in table 1:
Table 1:Treat the wet osteopathy effect checking of chill
It is made from the experiment contrast result of upper table 1, Chinese medicine composition provided by the invention and by the Chinese medicine composition
Plaster can effectively alleviate rheumatism bone disease symptom, the embodiment of the present invention it can be seen from embodiment 1-5 and comparative example 1-10
External application Chinese medicine combination becomes apparent to the effect for alleviating the symptom of rheumatism bone disease.As can be seen here, by the cooperation between each component and again
With effect, the therapeutic effect of Chinese medicine composition can be effectively improved.Meanwhile can be with by embodiment 1-5 and embodiment 6-19 contrasts
Find out, the preparation method of plaster of the preparation that the present embodiment provides comprising the embodiment 1-5 Chinese medicine compositions provided, this reality can be made
Apply the Chinese medicine composition that a 1-5 is provided and preferably play drug effect, the preparation method that wherein embodiment 8 provides is optimal.By embodiment 8
The preparation method preparation embodiment 5 provided using the present embodiment is can be seen that with embodiment 16-19 and comparative example 11-12 to provide
The obtained plaster treatment effect of Chinese medicine composition it is optimal.
Effect example 2:
Clinic, which is collected, has protrasion of the lumbar intervertebral disci shape patient 560, wherein male 280, women 280, average mark
Into 28 groups, every group of male patient 10, female patient 10, at 18~75 years old age, the age is randomly assigned.
Patient possesses following symptom:Scoliosis, waist physiology lordosis disappear, and pathological interspinal disk may narrow, neighboring edge
There is osteophytosis, CT examination can show position and the degree of disc herniation.
Treatment method:Affected part is cleaned after the Chinese medicine composition decocting that embodiment 1~5 and comparative example 1~10 are provided, daily
Clean three times, the plaster that embodiment 6~19 and comparative example 1~12 provide is affixed on affected part, pastes within every 24 hours one, blank control group in
Paste the medical proof fabric of formed objects in affected part.
Curative effect determinate standard:Recovery from illness:CT examination waist dish outstanding position recovers normal or pain in waist and lower extremities disappears, leg raising straight
More than 70 °, can extensive recovery operation;It is effective:Pain in waist and lower extremities mitigates, and waist movable function improves;It is invalid:Substantially change with nothing before treatment
It is kind.As a result statistics is as shown in table 2:
Table 2:Treat the wet osteopathy effect checking of chill
It is made from the experiment contrast result of upper table 2, Chinese medicine composition provided by the invention and by the Chinese medicine composition
Plaster can effectively alleviate protrasion of the lumbar intervertebral disci shape, the implementation of the present invention it can be seen from embodiment 1-5 and comparative example 1-10
The external application Chinese medicine combination of example becomes apparent to the effect for alleviating protrasion of the lumbar intervertebral disci shape.As can be seen here, matching somebody with somebody between each component is passed through
Conjunction and complex role, the therapeutic effect of Chinese medicine composition can be effectively improved.Meanwhile by 6-19 pairs of embodiment 1-5 and embodiment
, can than the preparation method that can be seen that plaster of the preparation of the present embodiment offer comprising the embodiment 1-5 Chinese medicine compositions provided
The Chinese medicine composition for providing the present embodiment 1-5 preferably plays drug effect, and the preparation method that wherein embodiment 8 provides is optimal.By
Embodiment 18 and embodiment 16-19 and comparative example 11-12, which can be seen that the preparation method provided using the present embodiment and prepare, to be implemented
The plaster treatment effect that the Chinese medicine composition that example 5 provides obtains is optimal.
Effect example 3:
Clinic, which is collected, has arthroedema patient with sympotoms 560, wherein male 280, women 280, is divided into
28 groups, every group of male patient 10, female patient 10, at 18~75 years old age, the age is randomly assigned.Case is included all to meet
KOA merges arthroedema Western medicine diagnostic criteria.
Treatment method:Affected part is cleaned after the Chinese medicine composition decocting that embodiment 1~5 and comparative example 1~10 are provided, daily
Clean three times, the plaster that embodiment 6~19 and comparative example 1~12 provide is affixed on affected part, pastes within every 24 hours one, blank control group in
Paste the medical proof fabric of formed objects in affected part.
Curative effect determinate standard, with reference to the Ministry of Public Health《New Chinese medicine guideline of clinical investigations》Plays are drafted, recovery from illness:Joint
The symptoms such as pain, swelling disappear, and joint motion is normal, and integration, which is reduced, is more than 95%;It is effective:Pain, joint motion are obviously improved,
Integration reduces 70%~95%;Effectively:Pain, joint motion make moderate progress, and integration reduces 30%~70%;It is invalid:Pain, pass
Section activity is not improved, and integration, which is reduced, is less than 30%;Calculation formula:Integrated before (being integrated before treatment after integration-treatment)/treatment
× 100%, as a result as shown in table 3:
Table 3:Treat arthroedema effect checking
It is made from the experiment contrast result of upper table 3, Chinese medicine composition provided by the invention and by the Chinese medicine composition
Plaster can effectively alleviate arthroedema symptom, the embodiment of the present invention it can be seen from embodiment 1-5 and comparative example 1-10
External application Chinese medicine combination to alleviate arthroedema symptom effect become apparent from.As can be seen here, by the cooperation between each component with
Complex role, the therapeutic effect of Chinese medicine composition can be effectively improved.Meanwhile can by embodiment 1-5 and embodiment 6-19 contrasts
To find out, the preparation method for plaster of the preparation comprising the embodiment 1-5 Chinese medicine compositions provided that the present embodiment provides, this can be made
The Chinese medicine composition that embodiment 1-5 is provided preferably plays drug effect, and the preparation method that wherein embodiment 8 provides is optimal.By implementing
Example 18 and embodiment 16-19 and comparative example 11-12 can be seen that the preparation method provided using the present embodiment and prepare embodiment 5
The plaster treatment effect that the Chinese medicine composition of offer obtains is optimal.
Model case:
Several model cases are lifted below goes on to say beneficial effects of the present invention.
Model case 1
Zhang, female, 60 years old, treating rheumatic ostealgia, walk to alter based on pain with four limbs large joint, with joint it is miserable, it is numb, bend and stretch not
Profit, meet it is cold aggravate, obtain hot, subtract bitterly, daytime light night weight, joint can not be bent and stretched.Plaster provided by the invention is affixed on affected part daily,
Ostalgia mitigates after three days, and a week is used continuously, and joint is bent and stretched the limbs freely, and ostalgia disappears substantially, and follow-up after one month, symptom disappears
Lose, two middle of the month meet overcast and rainy or aversion to cold weather, symptom and do not recurred.
Model case 2
Feng, man, 45 years old, treating rheumatic ostealgia, upper left acroanesthesia was powerless, and raw weather pain aggravates, and left upper extremity joint can not
Bend and stretch, plaster provided by the invention is affixed on affected part daily, ostalgia then mitigates after two hours, and a week, joint is used continuously
Bend and stretch the limbs freely, left upper extremity freedom of movement, ostalgia disappears, follow-up after one month, and symptom disappears, and two middle of the month meet overcast and rainy or aversion to cold day
Gas, symptom do not recur.
Model case 3
Lee, female, 68 years old, CT diagnostic results waist 3~4 and 4~5 disc herniations were affixed on plaster provided by the invention
Affected part normal position of CT review results recovery after 40 days.
Model case 4
Slowly certain, man, 61 years old, the protrusion of lumber intervertebral disc of waist 2~3 and 3~4, affected part is affixed on 30 days with plaster provided by the invention
CT review results recover normal position afterwards.
Model case 5
Ancestor certain, teacher, 52 years old, right scapulohumeral periarthritis, ligament adhesion, hydrops, affected part is affixed on 50 days with plaster provided by the invention
After fully recover.
Model case 6
Jiang, female, 58 years old, office worker, protrusion of lumber intervertebral disc, affected part is affixed on 20 days more with plaster provided by the invention.
Model case 7
Yan, female, 61 years old, peasant, right knee was once performed the operation, and recurrence, knee swelling, inconvenient walking, there is six months, with this
The plaster that invention provides is affixed on affected part 40 days more.
Model case 8
Certain is cared for, 19 years old, the interverbebral disc of waist 3~4 protrusion, injury gained in sports, affected part is affixed on 30 days with plaster provided by the invention, fullys recover from an illness
More.
Model case 9
Lee, 16 years old, knee kinematics damage, it is affixed on affected part 15 days with plaster provided by the invention, fully recovers.
Model case 10
Mr. Ji, female, 55 years old, fall accidentally, left knee joint moderate swelling, fluid wave is dynamic obvious, is kneecap when politics is stretched
There is ballottement, drawing liquid 2ml send laboratory, and microscopy is omission timber, and tongue nature is light, tongue is thin in vain, arteries and veins is thin and delicate, with plaster provided by the invention
Affected part 7 days is affixed on to fully recover, after one month follow-up do not recur.
Finally it should be noted that:Various embodiments above is merely illustrative of the technical solution of the present invention, rather than its limitations;To the greatest extent
The present invention is described in detail with reference to foregoing embodiments for pipe, it will be understood by those within the art that:Its according to
The technical scheme described in foregoing embodiments can so be modified, either which part or all technical characteristic are entered
Row equivalent substitution;And these modifications or replacement, the essence of appropriate technical solution is departed from various embodiments of the present invention technology
The scope of scheme.
Claims (10)
1. a kind of Chinese medicine composition, it is characterised in that count mainly includes following component in parts by weight:30~50 parts of Impatientis,
20~35 parts of radix rehmanniae recen, 15~35 parts of Radix Angelicae Sinensis, 12~30 parts of rhizoma arisaematis, 15~25 parts of monkshood, 15~25 parts of radix aconiti agrestis, notopterygium root 10~
25 parts, 10~25 parts of levisticum, 10~25 parts of frankincense, 10~25 parts of myrrh, 10~25 parts of rhizoma zingiberis, 10~25 parts of Chinese cassia tree, cloves 10
~25 parts, 20~35 parts of the Fen, Common St.Paulswort Herbs of the root of Chinese clematis 30~50,18~35 parts of golden cypress, 18~35 parts of Chinese honey locust (fruit), corydalis tuber 20~30
Part, 5~15 parts of calamine, 5~15 parts of alumen, 5~10 parts of native copper, 5~10 parts of hydrargyrum chloratum compositum, 15~25 parts of Soil unit and ramulus acaciae
20~30 parts.
2. Chinese medicine composition according to claim 1, it is characterised in that count mainly includes following component in parts by weight:
42~48 parts of Impatientis, 28~32 parts of radix rehmanniae recen, 25~32 parts of Radix Angelicae Sinensis, 18~28 parts of rhizoma arisaematis, 18~22 parts of monkshood, radix aconiti agrestis 18
~22 parts, 18~25 parts of notopterygium root, 18~22 parts of levisticum, 18~22 parts of frankincense, 15~22 parts of myrrh, 10~20 parts of rhizoma zingiberis, Chinese cassia tree
12~18 parts, 12~18 parts of cloves, 27~32 parts of the Fen, Common St.Paulswort Herbs of the root of Chinese clematis 40~48,25~32 parts of golden cypress, Chinese honey locust (fruit) 25~32
Part, 22~28 parts of corydalis tuber, 8~12 parts of calamine, 8~12 parts of alumen, 7~9 parts of native copper, 7~9 parts of hydrargyrum chloratum compositum, Soil unit 18
~22 parts and 22~28 parts of catechu.
3. Chinese medicine composition according to claim 2, it is characterised in that count mainly includes following component in parts by weight:
45 parts of Impatientis, 30 parts of radix rehmanniae recen, 30 parts of Radix Angelicae Sinensis, 25 parts of rhizoma arisaematis, 20 parts of monkshood, 20 parts of radix aconiti agrestis, 20 parts of notopterygium root, levisticum 20
Part, 20 parts of frankincense, 20 parts of myrrh, 15 parts of rhizoma zingiberis, 15 parts of Chinese cassia tree, 15 parts of cloves, 30 parts of the Fen, Common St.Paulswort Herbs of the root of Chinese clematis 45, golden cypress 30
Part, 30 parts of Chinese honey locust (fruit), 25 parts of corydalis tuber, 10 parts of calamine, 10 parts of alumen, 8 parts of native copper, 8 parts of hydrargyrum chloratum compositum, 20 parts of Soil unit and youngster
25 parts of tea.
4. application of the Chinese medicine composition in the medicine for preparing treatment osteopathy as described in claim any one of 1-3.
5. a kind of plaster, include the Chinese medicine composition described in claim any one of 1-3.
6. the preparation method of plaster as claimed in claim 5, it is characterised in that:The preparation method mainly includes will by right
Chinese medicine composition described in any one of 1-3 is asked to be mixed evenly after crushing with matrix, the step of spreading onto carrier.
7. preparation method according to claim 6, it is characterised in that the preparation method is also included the Chinese traditional medicine composition
Thing is grouped as follows, the step of matrix is sequentially added after crushing, and packet mode is as follows:
A groups:Impatientis, radix rehmanniae recen, Radix Angelicae Sinensis, rhizoma arisaematis, monkshood, radix aconiti agrestis, frankincense, myrrh, rhizoma zingiberis, Chinese cassia tree, cloves, Chinese honey locust (fruit),
Corydalis tuber and catechu;
B groups:Golden cypress, root of Chinese clematis, Common St.Paulswort Herbs, notopterygium root and levisticum;
C groups:Alumen, calamine, native copper and hydrargyrum chloratum compositum;
Preferably, the component of the A groups mixes after being crushed to 120~220 mesh with matrix;
Preferably, the component of the B groups is crushed to 35~100 mesh, adds solvent soaking 150~168 hours, and the solvent is steamed
Mixed after hair with matrix.
8. preparation method according to claim 6, it is characterised in that the matrix and the ratio of Chinese medicine composition mixing
Example is 1:1.1~1:1.6.
9. preparation method according to claim 6, it is characterised in that the matrix mainly includes medical hot melt adhesive.
10. preparation method according to claim 6, it is characterised in that the preparation method also includes adding in the matrix
Enter the step of bleeding agent stirs and evenly mixs.
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CN108339201A (en) * | 2018-04-08 | 2018-07-31 | 无锡瑞宁科技有限公司 | A kind of patch and preparation method thereof for promoting postoperative intestine to wriggle and urinate |
CN109106748A (en) * | 2018-10-18 | 2019-01-01 | 岳明法 | A kind of Chinese medicine for treating prolapse of lumbar intervertebral disc |
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CN102552714A (en) * | 2012-02-28 | 2012-07-11 | 石佩甫 | Plaster for treating facial neuroparalysis and rheumatic arthritis |
CN104435553A (en) * | 2014-12-04 | 2015-03-25 | 范继国 | Effective bony spur ointment and preparation method |
CN104435185A (en) * | 2014-07-31 | 2015-03-25 | 高平 | Bonesetting liquid for treating lumbar disc herniation |
CN106491884A (en) * | 2016-11-04 | 2017-03-15 | 青岛丰泽中兴科技服务有限公司 | A kind of bone strengthening plaster |
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CN101244247A (en) * | 2007-02-16 | 2008-08-20 | 李新华 | Pharmaceutical combination for treating cervical vertebra disease and waist and leg pain, and preparation thereof |
CN102552714A (en) * | 2012-02-28 | 2012-07-11 | 石佩甫 | Plaster for treating facial neuroparalysis and rheumatic arthritis |
CN104435185A (en) * | 2014-07-31 | 2015-03-25 | 高平 | Bonesetting liquid for treating lumbar disc herniation |
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