CN111655247A - 用lsd抑制剂与pd1结合拮抗剂的组合增强t细胞功能和治疗t细胞功能障碍病症 - Google Patents

用lsd抑制剂与pd1结合拮抗剂的组合增强t细胞功能和治疗t细胞功能障碍病症 Download PDF

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CN111655247A
CN111655247A CN201880087971.0A CN201880087971A CN111655247A CN 111655247 A CN111655247 A CN 111655247A CN 201880087971 A CN201880087971 A CN 201880087971A CN 111655247 A CN111655247 A CN 111655247A
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cells
cell
lsd
cancer
binding
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S·饶
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Ebx Treatment Pte Ltd
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Ebx Treatment Pte Ltd
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    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
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CN201880087971.0A 2017-11-29 2018-11-28 用lsd抑制剂与pd1结合拮抗剂的组合增强t细胞功能和治疗t细胞功能障碍病症 Pending CN111655247A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2017904811A AU2017904811A0 (en) 2017-11-29 Immunopotentiating compositions and uses therefor
AU2017904811 2017-11-29
PCT/AU2018/051268 WO2019104381A1 (en) 2017-11-29 2018-11-28 Enhancing t-cell function and treating a t-cell dysfunctional disorder with a combination of an lsd inhibitor and a pd1 binding antagonist

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CN111655247A true CN111655247A (zh) 2020-09-11

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CN201880087971.0A Pending CN111655247A (zh) 2017-11-29 2018-11-28 用lsd抑制剂与pd1结合拮抗剂的组合增强t细胞功能和治疗t细胞功能障碍病症

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US (1) US20210186905A1 (https=)
EP (1) EP3716963A4 (https=)
JP (1) JP2021504399A (https=)
CN (1) CN111655247A (https=)
AU (1) AU2018377852B2 (https=)
CA (1) CA3083373A1 (https=)
SG (1) SG11202004767TA (https=)
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CN117159570A (zh) * 2023-11-01 2023-12-05 云南中医药大学 6-酰氧基甘露糖叠氮乙苷衍生物与氟康唑联合在制备抗耐药白念珠菌药物中的应用

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US12435128B2 (en) 2017-05-31 2025-10-07 Taiho Pharmaceutical Co., Ltd. Method for predicting therapeutic effect of LSD1 inhibitor based on expression of INSM1
EP3714883A1 (en) * 2019-03-25 2020-09-30 AC BioScience SA Indole containing small chemical compounds and use thereof for the non-cytotoxic and immunological treatment of cancer
WO2020256628A1 (en) 2019-06-20 2020-12-24 Amniotics Ab An apparatus for filtering amniotic fluid
CA3149964A1 (en) 2019-09-03 2021-03-11 Michelle Wykes Methods and agents for determining patient status
AU2020368845A1 (en) 2019-10-18 2022-05-12 Amniotics Ab Processes and apparatuses for obtaining amniotic mesenchymal stem cells from amniotic fluid and cells derived thereof
MX2022005812A (es) 2019-11-13 2022-08-16 Taiho Pharmaceutical Co Ltd Metodos de tratamiento de enfermedades y trastornos relacionados con desmetilasa 1 especifica de lisina con inhibidores de desmetilasa 1 especifica de lisina.
US20220348876A1 (en) * 2019-11-28 2022-11-03 Amniotics Ab Metabolism guides definitive lineage specification during endothelial to hematopoietic transition
EP4114398A1 (en) * 2020-03-06 2023-01-11 Celgene Quanticel Research, Inc. Combination of an lsd-1 inhibitor and nivolumab for use in treating sclc or sqnsclc
WO2021195723A1 (en) * 2020-04-03 2021-10-07 The Council Of The Queensland Institute Of Medical Research "methods for treatment of coronavirus infections"
CA3179176A1 (en) * 2020-04-03 2021-10-07 University Of Florida Research Foundation, Incorporated Stem cell immunomodulatory therapy for covid-19 infection
EP4232163A4 (en) * 2020-10-22 2024-10-30 The Regents of University of California MONOAMIN OXIDASE BLOCKADE THERAPY FOR THE TREATMENT OF CANCER BY REGULATION OF ANTITUMOR T-CELL IMMUNITY
EP4232036A4 (en) * 2020-10-22 2024-10-30 The Regents of University of California MONOAMINE OXIDASE BLOCKADE THERAPY FOR CANCER TREATMENT BY REGULATION OF TUMOR-ASSOCIATED MACROPHAGES (TAMs)
US12435308B2 (en) 2020-11-06 2025-10-07 Amniotics Ab Immunomodulation by amniotic fluid mesenchymal stem cells
US20250049757A1 (en) * 2021-09-30 2025-02-13 Taiho Pharmaceutical Co. Ltd. Combinatory therapy for cancer using biphenyl compound and immune checkpoint molecule regulator
WO2023077188A1 (en) * 2021-11-02 2023-05-11 Epiaxis Therapeutics Pty Ltd Proteinaceous molecules and uses therefor

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117159570A (zh) * 2023-11-01 2023-12-05 云南中医药大学 6-酰氧基甘露糖叠氮乙苷衍生物与氟康唑联合在制备抗耐药白念珠菌药物中的应用
CN117159570B (zh) * 2023-11-01 2024-01-23 云南中医药大学 6-酰氧基甘露糖叠氮乙苷衍生物与氟康唑联合在制备抗耐药白念珠菌药物中的应用

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EP3716963A1 (en) 2020-10-07
US20210186905A1 (en) 2021-06-24
EP3716963A4 (en) 2021-08-11
AU2018377852B2 (en) 2022-03-24
JP2021504399A (ja) 2021-02-15
CA3083373A1 (en) 2019-06-06
WO2019104381A1 (en) 2019-06-06
SG11202004767TA (en) 2020-06-29

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Application publication date: 20200911