AU2018377852B2 - Enhancing T-cell function and treating a T-cell dysfunctional disorder with a combination of an LSD inhibitor and a PD1 binding antagonist - Google Patents

Enhancing T-cell function and treating a T-cell dysfunctional disorder with a combination of an LSD inhibitor and a PD1 binding antagonist Download PDF

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AU2018377852B2
AU2018377852B2 AU2018377852A AU2018377852A AU2018377852B2 AU 2018377852 B2 AU2018377852 B2 AU 2018377852B2 AU 2018377852 A AU2018377852 A AU 2018377852A AU 2018377852 A AU2018377852 A AU 2018377852A AU 2018377852 B2 AU2018377852 B2 AU 2018377852B2
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cell
cancer
lsd
cells
trans
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AU2018377852A1 (en
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Sudha RAO
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Epiaxis Therapeutics Pty Ltd
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Epiaxis Therapeutics Pty Ltd
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    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
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AU2018377852A 2017-11-29 2018-11-28 Enhancing T-cell function and treating a T-cell dysfunctional disorder with a combination of an LSD inhibitor and a PD1 binding antagonist Active AU2018377852B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2017904811A AU2017904811A0 (en) 2017-11-29 Immunopotentiating compositions and uses therefor
AU2017904811 2017-11-29
PCT/AU2018/051268 WO2019104381A1 (en) 2017-11-29 2018-11-28 Enhancing t-cell function and treating a t-cell dysfunctional disorder with a combination of an lsd inhibitor and a pd1 binding antagonist

Publications (2)

Publication Number Publication Date
AU2018377852A1 AU2018377852A1 (en) 2020-06-18
AU2018377852B2 true AU2018377852B2 (en) 2022-03-24

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AU2018377852A Active AU2018377852B2 (en) 2017-11-29 2018-11-28 Enhancing T-cell function and treating a T-cell dysfunctional disorder with a combination of an LSD inhibitor and a PD1 binding antagonist

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US (1) US20210186905A1 (https=)
EP (1) EP3716963A4 (https=)
JP (1) JP2021504399A (https=)
CN (1) CN111655247A (https=)
AU (1) AU2018377852B2 (https=)
CA (1) CA3083373A1 (https=)
SG (1) SG11202004767TA (https=)
WO (1) WO2019104381A1 (https=)

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US11542473B2 (en) 2016-10-21 2023-01-03 Amniotics Ab Methods and compositions for generating hematopoietic cells
US12435128B2 (en) 2017-05-31 2025-10-07 Taiho Pharmaceutical Co., Ltd. Method for predicting therapeutic effect of LSD1 inhibitor based on expression of INSM1
EP3714883A1 (en) * 2019-03-25 2020-09-30 AC BioScience SA Indole containing small chemical compounds and use thereof for the non-cytotoxic and immunological treatment of cancer
WO2020256628A1 (en) 2019-06-20 2020-12-24 Amniotics Ab An apparatus for filtering amniotic fluid
CA3149964A1 (en) 2019-09-03 2021-03-11 Michelle Wykes Methods and agents for determining patient status
AU2020368845A1 (en) 2019-10-18 2022-05-12 Amniotics Ab Processes and apparatuses for obtaining amniotic mesenchymal stem cells from amniotic fluid and cells derived thereof
MX2022005812A (es) 2019-11-13 2022-08-16 Taiho Pharmaceutical Co Ltd Metodos de tratamiento de enfermedades y trastornos relacionados con desmetilasa 1 especifica de lisina con inhibidores de desmetilasa 1 especifica de lisina.
US20220348876A1 (en) * 2019-11-28 2022-11-03 Amniotics Ab Metabolism guides definitive lineage specification during endothelial to hematopoietic transition
EP4114398A1 (en) * 2020-03-06 2023-01-11 Celgene Quanticel Research, Inc. Combination of an lsd-1 inhibitor and nivolumab for use in treating sclc or sqnsclc
WO2021195723A1 (en) * 2020-04-03 2021-10-07 The Council Of The Queensland Institute Of Medical Research "methods for treatment of coronavirus infections"
CA3179176A1 (en) * 2020-04-03 2021-10-07 University Of Florida Research Foundation, Incorporated Stem cell immunomodulatory therapy for covid-19 infection
EP4232163A4 (en) * 2020-10-22 2024-10-30 The Regents of University of California MONOAMIN OXIDASE BLOCKADE THERAPY FOR THE TREATMENT OF CANCER BY REGULATION OF ANTITUMOR T-CELL IMMUNITY
EP4232036A4 (en) * 2020-10-22 2024-10-30 The Regents of University of California MONOAMINE OXIDASE BLOCKADE THERAPY FOR CANCER TREATMENT BY REGULATION OF TUMOR-ASSOCIATED MACROPHAGES (TAMs)
US12435308B2 (en) 2020-11-06 2025-10-07 Amniotics Ab Immunomodulation by amniotic fluid mesenchymal stem cells
US20250049757A1 (en) * 2021-09-30 2025-02-13 Taiho Pharmaceutical Co. Ltd. Combinatory therapy for cancer using biphenyl compound and immune checkpoint molecule regulator
WO2023077188A1 (en) * 2021-11-02 2023-05-11 Epiaxis Therapeutics Pty Ltd Proteinaceous molecules and uses therefor
CN117159570B (zh) * 2023-11-01 2024-01-23 云南中医药大学 6-酰氧基甘露糖叠氮乙苷衍生物与氟康唑联合在制备抗耐药白念珠菌药物中的应用

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CONDAMINE, T. et al. Cancer Research (July 2017) Vol.77 No.13, Supp. Supplement 1. Abstract Number: 4635 *

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AU2018377852A1 (en) 2020-06-18
EP3716963A1 (en) 2020-10-07
US20210186905A1 (en) 2021-06-24
EP3716963A4 (en) 2021-08-11
CN111655247A (zh) 2020-09-11
JP2021504399A (ja) 2021-02-15
CA3083373A1 (en) 2019-06-06
WO2019104381A1 (en) 2019-06-06
SG11202004767TA (en) 2020-06-29

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