CN111642748A - Anti-fatigue marine polypeptide composition and preparation method and application thereof - Google Patents
Anti-fatigue marine polypeptide composition and preparation method and application thereof Download PDFInfo
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- CN111642748A CN111642748A CN202010442771.1A CN202010442771A CN111642748A CN 111642748 A CN111642748 A CN 111642748A CN 202010442771 A CN202010442771 A CN 202010442771A CN 111642748 A CN111642748 A CN 111642748A
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/364—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/44—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing peptides or proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/48—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing plants or parts thereof, e.g. fruits, seeds, extracts
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
- A23J1/04—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from fish or other sea animals
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J3/00—Working-up of proteins for foodstuffs
- A23J3/04—Animal proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J3/00—Working-up of proteins for foodstuffs
- A23J3/30—Working-up of proteins for foodstuffs by hydrolysis
- A23J3/32—Working-up of proteins for foodstuffs by hydrolysis using chemical agents
- A23J3/34—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
- A23J3/341—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L31/00—Edible extracts or preparations of fungi; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
- A23L5/20—Removal of unwanted matter, e.g. deodorisation or detoxification
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Mycology (AREA)
- Inorganic Chemistry (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Marine Sciences & Fisheries (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
The invention discloses an anti-fatigue marine polypeptide composition which is prepared from the following raw materials, by weight, 30-40 parts of oyster, 10-20 parts of sea cucumber, 20-30 parts of rhizoma polygonati, 10-15 parts of cinnamon, 60-80 parts of white granulated sugar, 25-30 parts of liquorice, 30-35 parts of gordon euryale seed and 30-35 parts of poria cocos. The invention also discloses a preparation method and application of the composition. The composition of the invention prepares the polypeptide by using oyster and sea cucumber, and the special enzyme combination is adopted for enzymolysis in the preparation process, so that the nutritional ingredients of the oyster and the sea cucumber are well retained, the fishy smell of the polypeptide can be reduced, and the composition is further mixed with extracts of polygonatum, cinnamon, liquorice, gordon euryale seed and poria cocos, so that the fishy smell of the polypeptide is removed, a pleasant fragrance is formed, the finally formed composition can stimulate appetite and play a health care role on the body, and the rapid development of oyster and sea cucumber food industry is facilitated.
Description
Technical Field
The invention relates to the technical field of food, and in particular relates to an anti-fatigue marine polypeptide composition and a preparation method and application thereof.
Background
The polypeptide industry, as an industry which is not completely mature, covers a plurality of fields such as food, health care, medical treatment and the like, has wide sources of polypeptides, comes from plants, animals and microorganisms, and has huge potential. The polypeptide derived from the animal body has more unknown property than the polypeptide in the bodies of terrestrial animals, insects and birds due to the particularity of marine environment. The establishment of a polypeptide resource library and the research and application of key technologies such as polypeptide preparation by an enzymatic method, polypeptide preparation by a microbial fermentation method, polypeptide preparation by an artificial synthesis method and the like promote the research of the industry in the aspects of new technologies, new devices and new products.
The application of polypeptide, whether domestic or foreign, is in the rapid development stage, with the research deepening, the understanding of polypeptide is continuously deepened, and the superiority of functional peptide is more and more appreciated. People are increasingly willing to eat polypeptide products instead of daily protein intake.
The polypeptide industry is gradually derived from the medical industry to other industries, a new market is developed in the aspect of diversified products such as health food, common beverage, candy and the like, consumption requirements are developed, various products containing polypeptide concepts are developed for the consumption market, and the polypeptide industry is a new bright point for industrial consumption upgrading.
However, polypeptides derived from marine animals are often associated with characteristic fishy off-flavors and, therefore, are unacceptable for use as food products, hindering the development of marine polypeptide food products.
Disclosure of Invention
Aiming at the defect of fishy smell and peculiar smell of marine polypeptide food in the prior art, the invention provides the fatigue-resistant marine polypeptide composition, which can not only retain the nutritional ingredients of the marine polypeptide, but also has pleasant flavor, and the composition has the health-care effect of resisting fatigue while overcoming the defect of the flavor of the marine polypeptide by matching with traditional Chinese medicine components, thereby being beneficial to the vigorous development of the marine polypeptide food.
In order to achieve the purpose, the invention adopts the following technical scheme:
an anti-fatigue marine polypeptide composition is prepared from the following raw materials in parts by weight:
30-40 parts of oyster, 10-20 parts of sea cucumber, 20-30 parts of rhizoma polygonati, 10-15 parts of cinnamon, 60-80 parts of white granulated sugar, 25-30 parts of liquorice, 30-35 parts of gordon euryale seed and 30-35 parts of poria cocos.
Further, the composition containing the marine polypeptide is prepared from the following raw materials in parts by weight:
30 parts of oyster, 10 parts of sea cucumber, 20 parts of rhizoma polygonati, 15 parts of cinnamon, 80 parts of white granulated sugar, 25 parts of liquorice, 30 parts of gordon euryale seed and 30 parts of poria cocos.
The invention also provides a preparation method of the anti-fatigue marine polypeptide composition, which comprises the following steps:
preparing peptide from oysters: pretreating oysters, adding protease for enzymolysis, performing ultrafiltration on obtained enzymolysis liquid, and performing spray drying to obtain oyster peptide, wherein the protease comprises pepsin, bromelain and papain, the pepsin accounts for 0.3-0.5% of the weight of the oysters, the bromelain accounts for 0.2-0.5% of the weight of the oysters, and the papain accounts for 0.3-0.5% of the weight of the oysters;
preparing the peptide by using the sea cucumber: after sea cucumber pretreatment, adding protease for enzymolysis, and carrying out ultrafiltration and reduced pressure drying on the obtained enzymolysis liquid to obtain sea cucumber peptide, wherein the protease comprises papain and neutral protease, the papain accounts for 0.1-0.3% of the weight of the sea cucumber, and the neutral protease accounts for 0.1-0.3% of the weight of the sea cucumber;
traditional Chinese medicine extraction: mixing rhizoma polygonati, cinnamon, liquorice, gordon euryale seed and poria cocos, adding 15-20 times of water for extraction, filtering an extracting solution, and concentrating the extracting solution into a fluid extract;
preparing dry paste: drying the fluid extract until the water content is lower than 5%, pulverizing and sieving to obtain dry extract powder;
mixing: mixing Concha Ostreae peptide, Stichopus japonicus peptide, dry extract powder, and white sugar.
Further, the pretreatment of the oyster comprises unfreezing oyster meat, mincing the oyster meat, grinding and high-temperature sterilization, wherein the high-temperature sterilization temperature is 90-95 ℃, and the time is 20-30 min.
Further, in the step of preparing the peptide from the oyster, the enzymolysis liquid is filtered and concentrated, sterilized at the high temperature of 121-123 ℃ for 60-70 min, and then spray-dried.
Further, in the step of preparing the peptide from the sea cucumber, the pretreatment comprises the steps of soaking the sea cucumber in clear water, removing internal organs, and cleaning and stocking the clear water.
Further, in the step of preparing the peptide from the sea cucumber, enzymolysis is carried out at the pH of 6-8 and at the temperature of 40-45 ℃.
Further, in the step of preparing the peptide from the sea cucumber, the reduced pressure drying is carried out under the conditions of-0.1 MPa and 75-80 ℃, and the drying is carried out until the water content is less than or equal to 3%.
The invention also provides an application of the anti-fatigue marine polypeptide composition, wherein the composition is used for preparing the ginseng and oyster paste, and the ginseng and oyster paste further comprises the following raw materials in parts by weight: 25-30 parts of wolfberry fruit, 25-30 parts of Chinese yam, 5-10 parts of ginseng, 5-10 parts of eucommia male flower, 500-800 parts of maltose syrup and 2-5 parts of polysorbates.
The invention also provides an application of the anti-fatigue marine polypeptide composition, the composition is used for preparing oyster sea cucumber tablet candies, and the oyster sea cucumber tablet candies further comprise the following raw materials in parts by weight: 20-25 parts of maca powder, 20-22 parts of American ginseng powder, 8-10 parts of taurine, 20-22 parts of guarana extract, 18-20 parts of corn starch, 8-10 parts of magnesium stearate and 12-15 parts of coating premix.
Compared with the prior art, the invention has the beneficial effects that:
the composition of the invention prepares polypeptide by using oyster and sea cucumber, and special enzyme combination is adopted for enzymolysis in the preparation process, so that the nutritional ingredients of the oyster and the sea cucumber are well retained, the fishy smell of the polypeptide can be reduced, the composition is further mixed with the extract mixture of polygonatum, cinnamon, liquorice, gordon euryale seed and poria cocos, the fishy smell of the polypeptide is removed, and pleasant fragrance is formed, and the extracts of polygonatum, cinnamon, liquorice, gordon euryale seed and poria cocos are combined with the polypeptide substances of oyster and sea cucumber, so that the composition can resist fatigue and strengthen the body, and the finally formed composition can not only stimulate appetite of people, but also play a health-care role on the body, and is beneficial to the vigorous development of oyster and sea cucumber food industries.
In the invention, the sealwort is used as a traditional Chinese medicine component, has the effects of replenishing vital essence and treating tiredness and weakness, and is matched with cinnamon, gorgon fruit and liquorice which have the effects of replenishing middle-jiao and replenishing Qi, and polypeptide to form the anti-fatigue health food which is a nutrient product capable of being eaten for a long time.
Detailed Description
The technical solutions in the embodiments of the present invention are described clearly and completely below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments obtained by a person skilled in the art without making any inventive step are within the scope of the present invention.
An anti-fatigue marine polypeptide composition is prepared from the following raw materials in parts by weight:
30-40 parts of oyster, 10-20 parts of sea cucumber, 20-30 parts of rhizoma polygonati, 10-15 parts of cinnamon, 60-80 parts of white granulated sugar, 25-30 parts of liquorice, 30-35 parts of gordon euryale seed and 30-35 parts of poria cocos.
The preparation method of the anti-fatigue marine polypeptide composition comprises the following steps:
preparing peptide from oysters:
(1) pretreating oysters: thawing oyster meat, mincing, grinding and sterilizing at a high temperature of 90-95 ℃ for 20-30 min.
(2) And (3) protease enzymolysis: adding pepsin accounting for 0.3-0.5 percent of the weight of the oyster meat, bromelain accounting for 0.2-0.5 percent of the weight of the oyster meat and papain accounting for 0.3-0.5 percent of the weight of the oyster meat, and carrying out enzymolysis under the conditions of pH 4-6 and 45 ℃.
(3) Filtering and concentrating the enzymolysis liquid, and sterilizing at the high temperature of 121-123 ℃ for 60-70 min.
(4) And (5) spray drying.
The sea cucumber peptide preparation step:
(1) pre-treating sea cucumber: soaking sea cucumber in clear water, removing viscera, and cleaning and stocking in clear water.
(2) And (3) protease enzymolysis: adding papain accounting for 0.1-0.3 percent of the weight of the sea cucumber and neutral protease accounting for 0.1-0.3 percent of the weight of the sea cucumber, and carrying out enzymolysis in an environment with the pH of 6-8 and the temperature of 40-45 ℃.
(3) Filtering and concentrating the enzymolysis liquid, and then drying under reduced pressure: drying under-0.1 MPa at 75-80 deg.C until the water content is less than or equal to 3%.
The traditional Chinese medicine extraction step:
mixing rhizoma Polygonati, cortex Cinnamomi, Glycyrrhrizae radix, semen euryales, and Poria, adding 15-20 times of water, extracting for 2 times, filtering 2 times of extractive solutions, mixing, and concentrating to obtain fluid extract.
Preparing dry paste:
drying the fluid extract until the water content is lower than 5%, pulverizing, and sieving to obtain dry extract powder.
Mixing: mixing Concha Ostreae peptide, Stichopus japonicus peptide, dry extract powder, and white sugar.
Example 1
An anti-fatigue marine polypeptide composition is prepared from the following raw materials in parts by weight:
30 parts of oyster, 20 parts of sea cucumber, 30 parts of rhizoma polygonati, 10 parts of cinnamon, 80 parts of white granulated sugar, 25 parts of liquorice, 30 parts of gordon euryale seed and 30 parts of poria cocos.
The preparation method of the anti-fatigue marine polypeptide composition comprises the following steps:
preparing peptide from oysters:
(1) pretreating oysters: thawing oyster meat, mincing, grinding, and sterilizing at 92 deg.C for 30 min.
(2) And (3) protease enzymolysis: adding pepsin accounting for 0.3 percent of the weight of the oyster meat, bromelain accounting for 0.3 percent of the weight of the oyster meat and papain accounting for 0.3 percent of the weight of the oyster meat, and performing enzymolysis at the pH of 4-6 and at the temperature of 45 ℃.
(3) Filtering and concentrating the enzymolysis liquid, and sterilizing at the high temperature of 121-123 ℃ for 60-70 min.
(4) And (5) spray drying.
The sea cucumber peptide preparation step:
(1) pre-treating sea cucumber: soaking sea cucumber in clear water, removing viscera, and cleaning and stocking in clear water.
(2) And (3) protease enzymolysis: adding papain in an amount which is 0.2 percent of the weight of the sea cucumber and neutral protease in an amount which is 0.2 percent of the weight of the sea cucumber, and carrying out enzymolysis at the pH of 6-8 and the temperature of 40-45 ℃.
(3) Filtering and concentrating the enzymolysis liquid, and then drying under reduced pressure: drying under-0.1 MPa at 75-80 deg.C until the water content is less than or equal to 3%.
The traditional Chinese medicine extraction step:
mixing rhizoma Polygonati, cortex Cinnamomi, Glycyrrhrizae radix, semen euryales, and Poria, adding 15-20 times of water, extracting for 2 times, filtering 2 times of extractive solutions, mixing, and concentrating to obtain fluid extract.
Preparing dry paste:
drying the fluid extract until the water content is lower than 5%, pulverizing, and sieving to obtain dry extract powder.
Mixing: mixing Concha Ostreae peptide, Stichopus japonicus peptide, dry extract powder, and white sugar.
Example 2
An anti-fatigue marine polypeptide composition is prepared from the following raw materials in parts by weight:
40 parts of oyster, 10 parts of sea cucumber, 20 parts of rhizoma polygonati, 15 parts of cinnamon, 60 parts of white granulated sugar, 30 parts of liquorice, 35 parts of gordon euryale seed and 35 parts of poria cocos.
The preparation method of the anti-fatigue marine polypeptide composition comprises the following steps:
preparing peptide from oysters:
(1) pretreating oysters: thawing oyster meat, mincing, grinding, and sterilizing at 90 deg.C for 25 min.
(2) And (3) protease enzymolysis: adding pepsin accounting for 0.5 percent of the weight of the oyster meat, bromelain accounting for 0.2 percent of the weight of the oyster meat and papain accounting for 0.5 percent of the weight of the oyster meat, and performing enzymolysis at the pH of 4-6 and at the temperature of 45 ℃.
(3) Filtering and concentrating the enzymolysis liquid, and sterilizing at the high temperature of 121-123 ℃ for 60-70 min.
(4) And (5) spray drying.
The sea cucumber peptide preparation step:
(1) pre-treating sea cucumber: soaking sea cucumber in clear water, removing viscera, and cleaning and stocking in clear water.
(2) And (3) protease enzymolysis: adding papain accounting for 0.1 percent of the weight of the sea cucumber and neutral protease accounting for 0.3 percent of the weight of the sea cucumber, and carrying out enzymolysis at the pH of 6-8 and the temperature of 40-45 ℃.
(3) Filtering and concentrating the enzymolysis liquid, and then drying under reduced pressure: drying under-0.1 MPa at 75-80 deg.C until the water content is less than or equal to 3%.
The traditional Chinese medicine extraction step:
mixing rhizoma Polygonati, cortex Cinnamomi, Glycyrrhrizae radix, semen euryales, and Poria, adding 15-20 times of water, extracting for 2 times, filtering 2 times of extractive solutions, mixing, and concentrating to obtain fluid extract.
Preparing dry paste:
drying the fluid extract until the water content is lower than 5%, pulverizing, and sieving to obtain dry extract powder.
Mixing: mixing Concha Ostreae peptide, Stichopus japonicus peptide, dry extract powder, and white sugar.
Example 3
An anti-fatigue marine polypeptide composition is prepared from the following raw materials in parts by weight:
35 parts of oyster, 15 parts of sea cucumber, 25 parts of rhizoma polygonati, 12 parts of cinnamon, 70 parts of white granulated sugar, 28 parts of liquorice, 32 parts of gordon euryale seed and 32 parts of poria cocos.
The preparation method of the anti-fatigue marine polypeptide composition comprises the following steps:
preparing peptide from oysters:
(1) pretreating oysters: thawing oyster meat, mincing, grinding, and sterilizing at 92 deg.C for 30 min.
(2) And (3) protease enzymolysis: adding pepsin accounting for 0.3 percent of the weight of the oyster meat, bromelain accounting for 0.3 percent of the weight of the oyster meat and papain accounting for 0.3 percent of the weight of the oyster meat, and performing enzymolysis at the pH of 4-6 and at the temperature of 45 ℃.
(3) Filtering and concentrating the enzymolysis liquid, and sterilizing at the high temperature of 121-123 ℃ for 60-70 min.
(4) And (5) spray drying.
The sea cucumber peptide preparation step:
(1) pre-treating sea cucumber: soaking sea cucumber in clear water, removing viscera, and cleaning and stocking in clear water.
(2) And (3) protease enzymolysis: adding papain in an amount which is 0.2 percent of the weight of the sea cucumber and neutral protease in an amount which is 0.2 percent of the weight of the sea cucumber, and carrying out enzymolysis at the pH of 6-8 and the temperature of 40-45 ℃.
(3) Filtering and concentrating the enzymolysis liquid, and then drying under reduced pressure: drying under-0.1 MPa at 75-80 deg.C until the water content is less than or equal to 3%.
The traditional Chinese medicine extraction step:
mixing rhizoma Polygonati, cortex Cinnamomi, Glycyrrhrizae radix, semen euryales, and Poria, adding 15-20 times of water, extracting for 2 times, filtering 2 times of extractive solutions, mixing, and concentrating to obtain fluid extract.
Preparing dry paste:
drying the fluid extract until the water content is lower than 5%, pulverizing, and sieving to obtain dry extract powder.
Mixing: mixing Concha Ostreae peptide, Stichopus japonicus peptide, dry extract powder, and white sugar.
Example 4
The ginseng and crassostrea gigas cream prepared by applying the anti-fatigue marine polypeptide composition in the embodiment 1 further comprises the following raw materials in parts by weight: 25-30 parts of wolfberry fruit, 25-30 parts of Chinese yam, 5-10 parts of ginseng, 5-10 parts of eucommia male flower, 500-800 parts of maltose syrup and 2-5 parts of polysorbate.
The preparation method of the ginseng-astragalus-oyster paste comprises the following steps:
step one, extraction and concentration: cleaning specified amount of Ginseng radix (artificially planted), rhizoma Polygonati, Cordyceps militaris, fructus Lycii, Poria, rhizoma Dioscoreae, cortex Cinnamomi, Eucommiae cortex male flower, Glycyrrhrizae radix, and semen euryales with water, placing in extraction tank, adding 10 times of water, heating and boiling for extraction for 1.5 hr to give extractive solution, extracting for 2 times, removing residues, mixing the two extractive solutions, filtering with 200 mesh filter cloth, and concentrating the filtrate to relative density of 1.10 (measured at 60 deg.C) to obtain concentrated solution.
Step two, paste refining: adding part of maltose (1L about 800g), white sugar and appropriate amount of water into a jacketed pan, heating to dissolve into syrup, mixing with the concentrated solution, Concha Ostreae peptide powder, Stichopus japonicus peptide powder, and Guarana extract under heating and stirring, decocting to obtain paste, adding the rest maltose, polyoxyethylene (20), and sorbitan monooleate (Tween 80), and refining to obtain paste with relative density of about 1.38.
Step three, filling: and filling the prepared paste liquid.
Step four, packaging: and packaging the qualified semi-finished product to obtain a final finished product.
Example 5
An oyster sea cucumber tablet candy prepared by applying the composition containing marine polypeptide described in embodiments 1 to 3, further comprising the following raw materials in parts by weight: 20-25 parts of maca powder, 20-22 parts of American ginseng powder, 8-10 parts of taurine, 20-22 parts of guarana extract, 18-20 parts of corn starch, 8-10 parts of magnesium stearate and 12-15 parts of coating premix.
The preparation method of the oyster sea cucumber tablet candy comprises the following steps:
the marine polypeptide-containing composition described in examples 1 to 3 was mixed with maca powder, American ginseng powder, taurine, guarana extract, and corn starch in a three-dimensional mixer for 30 minutes. Then placing the mixture in a groove type mixer, starting stirring, uniformly and slowly adding 40% ethanol solution to prepare soft materials, and granulating by using a swing type granulator with a 14-mesh sieve. And (3) drying the prepared granules in an oven at 75-85 ℃ until the moisture content is 2-4%, and grading the granules by using a 14-mesh sieve. Adding magnesium stearate into the granules after finishing the granules, and mixing in a three-dimensional mixer. Then, the tablets were compressed to a size of 0.5 g/tablet. And coating the surface of the tablet with a coating premix (namely, transparent film coating powder).
The above description is only for the purpose of illustrating the preferred embodiments of the present invention, and is not intended to limit the present invention to the particular embodiments disclosed, so that all equivalents and modifications that do not depart from the spirit of the present invention are deemed to fall within the scope of the present invention.
Claims (10)
1. The anti-fatigue marine polypeptide composition is characterized by being prepared from the following raw materials in parts by weight:
30-40 parts of oyster, 10-20 parts of sea cucumber, 20-30 parts of rhizoma polygonati, 10-15 parts of cinnamon, 60-80 parts of white granulated sugar, 25-30 parts of liquorice, 30-35 parts of gordon euryale seed and 30-35 parts of poria cocos.
2. The composition containing marine polypeptide of claim 1, which is prepared from the following raw materials in parts by weight:
30 parts of oyster, 10 parts of sea cucumber, 20 parts of rhizoma polygonati, 15 parts of cinnamon, 80 parts of white granulated sugar, 25 parts of liquorice, 30 parts of gordon euryale seed and 30 parts of poria cocos.
3. A method for preparing the composition of anti-fatigue marine polypeptides of claim 1, characterized by comprising the steps of:
preparing peptide from oysters: pretreating oysters, adding protease for enzymolysis, performing ultrafiltration on obtained enzymolysis liquid, and performing spray drying to obtain oyster peptide, wherein the protease comprises pepsin, bromelain and papain, the pepsin accounts for 0.3% -0.5% of the weight of the oysters, the bromelain accounts for 0.2% -0.5% of the weight of the oysters, and the papain accounts for 0.3% -0.5% of the weight of the oysters;
preparing the peptide by using the sea cucumber: after sea cucumber pretreatment, adding protease for enzymolysis, and performing ultrafiltration and reduced pressure drying on the obtained enzymolysis liquid to obtain sea cucumber peptide, wherein the protease comprises papain and neutral protease, the papain accounts for 0.1-0.3% of the weight of the sea cucumber, and the neutral protease accounts for 0.1-0.3% of the weight of the sea cucumber;
traditional Chinese medicine extraction: mixing rhizoma polygonati, cinnamon, liquorice, gordon euryale seed and poria cocos, adding 15-20 times of water for extraction, filtering an extracting solution, and concentrating the extracting solution into a fluid extract;
preparing dry paste: drying the fluid extract until the water content is lower than 5%, pulverizing and sieving to obtain dry extract powder;
mixing: mixing Concha Ostreae peptide, Stichopus japonicus peptide, dry extract powder, and white sugar.
4. A process for the preparation of a composition of anti-fatigue marine polypeptides according to claim 3, characterized in that: the oyster pretreatment comprises the steps of unfreezing oyster meat, mincing the oyster meat, grinding and sterilizing at a high temperature of 90-95 ℃ for 20-30 min.
5. A process for the preparation of a composition of anti-fatigue marine polypeptides according to claim 3, characterized in that: in the step of preparing the peptide from the oyster, after filtering and concentrating the enzymolysis liquid, sterilizing the enzymolysis liquid at the temperature of between 121 and 123 ℃ for 60 to 70min, and then performing spray drying.
6. A process for the preparation of a composition of anti-fatigue marine polypeptides according to claim 3, characterized in that: in the step of preparing the peptides from the sea cucumbers, the pretreatment comprises the steps of soaking the sea cucumbers in clear water, removing internal organs, and breeding in clear water after cleaning.
7. A process for the preparation of a composition of anti-fatigue marine polypeptides according to claim 3, characterized in that: in the step of preparing the peptide from the sea cucumber, enzymolysis is carried out at the pH of 6-8 and at the temperature of 40-45 ℃.
8. A process for the preparation of a composition of anti-fatigue marine polypeptides according to claim 3, characterized in that: in the step of preparing the peptide from the sea cucumber, the reduced pressure drying is carried out under the conditions of-0.1 MPa and 75-80 ℃, and the drying is carried out until the water content is less than or equal to 3%.
9. The application of the composition of claim 1, wherein the composition is used for preparing the ginseng and oyster paste, and the ginseng and oyster paste further comprises the following raw materials in parts by weight: 25-30 parts of wolfberry fruit, 25-30 parts of Chinese yam, 5-10 parts of ginseng, 5-10 parts of eucommia male flower, 500-800 parts of maltose syrup and 2-5 parts of polysorbate.
10. The application of the composition of claim 1, wherein the composition is used for preparing oyster sea cucumber tabletting candies, and the oyster sea cucumber tabletting candies further comprise the following raw materials in parts by weight: 20-25 parts of maca powder, 20-22 parts of American ginseng powder, 8-10 parts of taurine, 20-22 parts of guarana extract, 18-20 parts of corn starch, 8-10 parts of magnesium stearate and 12-15 parts of coating premix.
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