CN111630043A - 含环化合物、其制备方法及其在医药上的应用 - Google Patents
含环化合物、其制备方法及其在医药上的应用 Download PDFInfo
- Publication number
- CN111630043A CN111630043A CN201980009258.9A CN201980009258A CN111630043A CN 111630043 A CN111630043 A CN 111630043A CN 201980009258 A CN201980009258 A CN 201980009258A CN 111630043 A CN111630043 A CN 111630043A
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/56—Amides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/08—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing alicyclic rings
Abstract
本发明涉及一种如式(I)所示的含环化合物、所述化合物的立体异构体、互变异构体或其混合物，所述化合物药学上可接受的盐、多晶型物、共晶物或溶剂合物，或者，所述化合物的稳定同位素衍生物、代谢物或前药，或者制备方法及用途。
Description
PCT国内申请，说明书已公开。
Claims (37)
- PCT国内申请，权利要求书已公开。
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2018102222673 | 2018-03-19 | ||
| CN201810222267 | 2018-03-19 | ||
| CN201811331310 | 2018-11-09 | ||
| CN2018113313106 | 2018-11-09 | ||
| PCT/CN2019/078346 WO2019179369A1 (zh) | 2018-03-19 | 2019-03-15 | 含环化合物、其制备方法及其在医药上的应用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN111630043A true CN111630043A (zh) | 2020-09-04 |
| CN111630043B CN111630043B (zh) | 2022-02-15 |
Family
ID=67988140
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201980009258.9A Active CN111630043B (zh) | 2018-03-19 | 2019-03-15 | 含环化合物、其制备方法及其在医药上的应用 |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN111630043B (zh) |
| WO (1) | WO2019179369A1 (zh) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20190040990A (ko) * | 2016-08-26 | 2019-04-19 | 브리스톨-마이어스 스큅 컴퍼니 | 인돌아민 2,3-디옥시게나제의 억제제 및 그의 사용 방법 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106999450A (zh) * | 2014-11-05 | 2017-08-01 | 弗莱塞斯生物科学公司 | 免疫调节剂 |
| WO2017192813A1 (en) * | 2016-05-04 | 2017-11-09 | Bristol-Myers Squibb Company | Inhibitors of indoleamine 2,3-dioxygenase and methods of their use |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2019528301A (ja) * | 2016-08-26 | 2019-10-10 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | インドールアミン２，３−ジオキシゲナーゼの阻害剤およびその使用方法 |
-
2019
- 2019-03-15 CN CN201980009258.9A patent/CN111630043B/zh active Active
- 2019-03-15 WO PCT/CN2019/078346 patent/WO2019179369A1/zh active Application Filing
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106999450A (zh) * | 2014-11-05 | 2017-08-01 | 弗莱塞斯生物科学公司 | 免疫调节剂 |
| WO2017192813A1 (en) * | 2016-05-04 | 2017-11-09 | Bristol-Myers Squibb Company | Inhibitors of indoleamine 2,3-dioxygenase and methods of their use |
Also Published As
| Publication number | Publication date |
|---|---|
| CN111630043B (zh) | 2022-02-15 |
| WO2019179369A1 (zh) | 2019-09-26 |
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