CN111603525A - Preparation method and application of plant extract for treating tonsillitis and pharyngolaryngitis - Google Patents
Preparation method and application of plant extract for treating tonsillitis and pharyngolaryngitis Download PDFInfo
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- CN111603525A CN111603525A CN202010643875.9A CN202010643875A CN111603525A CN 111603525 A CN111603525 A CN 111603525A CN 202010643875 A CN202010643875 A CN 202010643875A CN 111603525 A CN111603525 A CN 111603525A
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- pharyngolaryngitis
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- black sesame
- tonsillitis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Otolaryngology (AREA)
- Inorganic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention provides a preparation method and application of a plant extract for treating tonsillitis and pharyngolaryngitis. The effective components of the Chinese medicinal composition comprise semen Sesami Niger, Sal, folium Camelliae sinensis, and Glycyrrhrizae radix. The composition of the invention can be tablets, pills, granules or oral liquid. The traditional Chinese medicine composition has a remarkable treatment effect on the tonsillitis and the sphagitis.
Description
Technical Field
The invention belongs to the technical field of plant extraction and biological pharmacy, and particularly relates to a preparation method and application of a plant extract for treating tonsillitis and pharyngolaryngitis.
Background
At present, the oxidation of a human body is aggravated, the immunity of the human body is reduced and the resistance is reduced due to environmental pollution and food pollution; acute and chronic pharyngolaryngitis and tonsillitis are common, and especially tonsillitis is easily obtained by children; seriously harming the health of people; the treatment with chemical drugs has certain side effects, and particularly, the drug resistance is easy to generate when the treatment is used for a plurality of times.
The black sesame salt, tea and liquorice are known to have the function of resisting respiratory tract inflammation; the effect of resisting respiratory tract inflammation is enhanced through a reasonable formula and a certain process technology, and the plant water extract oral liquid for treating tonsillitis and sphagitis with good effect is of great significance.
Disclosure of Invention
The invention aims to: provides a preparation method and application of a plant extract for treating tonsillitis and pharyngolaryngitis.
The technical scheme adopted by the invention is as follows: a preparation method of a plant extract for treating tonsillitis and pharyngolaryngitis is characterized by comprising the following steps:
s1, cooked black sesame and salt composition: stirring the mixture of black sesame and salt uniformly, and frying the black sesame to obtain a cooked black sesame salt composition;
s2, extracting immersion liquid: mixing cooked semen Sesami Niger and salt composition, folium Camelliae sinensis, Glycyrrhrizae radix, and water, and heating to obtain water extractive solution;
s3, filtering: filtering the water extract obtained in the step S2 by a filter membrane to remove impurities to obtain water extract fine filtrate;
s4, filling and sterilizing: and (5) filling the water-extracted fine-filtered liquid obtained in the step (S3) into an oral liquid bottle, and sterilizing at high temperature to obtain a finished product.
The reaction mechanism of the invention is as follows: the invention combines the cooked black sesame and salt composition, the tea and the liquorice and fully dissolves and combines the effective components of the water extraction and fine filtration liquid, has obvious effect of treating the tonsillitis and the sphagitis and has no side effect.
Further, the extraction of the extract in step S2 includes the steps of mixing the cooked black sesame and salt composition, tea leaves, and licorice: the weight ratio of water is as follows: 3-5: 1-3: 10-60, heating and extracting at 90-100 deg.C for 30-60 min; through a large number of experiments, the optimal proportion, extraction temperature and extraction time are obtained, and the effective ingredients in the cooked black sesame salt composition, the tea leaves and the liquorice can be fully dissolved in water, so that the raw materials are utilized to the maximum extent.
Further, the impurities removed by the filtration in the step S3 are substances larger than 0.25 micron, and the pore size of the filtration membrane used for the filtration is smaller than or equal to 0.25 micron; the water extraction fine filtration liquid has high purity and no precipitation impurity.
Further, the temperature for sterilization in the filling and sterilizing in the step S4 is 104 to 128 ℃; the time is 10 to 90 minutes; the product is sterilized after being filled, so that the curative effect of the product during the shelf life is ensured.
Further, in the step S4, the capacity of the oral liquid bottle during filling and sterilizing is 10-50 ml/piece of the oral liquid bottle; the qualified oral liquid bottle can be selected according to the dose.
The plant extract for treating tonsillitis and pharyngolaryngitis has application in preparing traditional Chinese medicines for treating tonsillitis and pharyngolaryngitis; can be used for treating tonsillitis and pharyngolaryngitis with good therapeutic effect.
In summary, due to the adoption of the technical scheme, the invention has the beneficial effects that:
the invention has simple process, high extraction and utilization rate of effective components, obvious administration effect, homology of medicine and food and no toxic or side effect.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
A preparation method of plant extract for treating tonsillitis and pharyngolaryngitis is characterized by comprising the following steps:
s1, cooked black sesame and salt composition: stirring the mixture of black sesame and salt uniformly, and frying the black sesame to obtain a cooked black sesame salt composition;
s2, extracting immersion liquid: mixing cooked semen Sesami Niger and salt composition, folium Camelliae sinensis, Glycyrrhrizae radix, and water, and heating to obtain water extractive solution; the extraction liquid comprises cooked black sesame and salt composition, tea and liquorice: the weight ratio of water is as follows: 3-5: 1-3: 10-60, heating and extracting at 90-100 deg.C for 30-60 min; through a large number of experiments, the optimal proportion, extraction temperature and extraction time are obtained, and the effective ingredients in the cooked black sesame salt composition, the tea leaves and the liquorice can be fully dissolved in water, so that the raw materials are utilized to the maximum extent.
S3, filtering: filtering the water extracting solution obtained in the step S2 through a filter membrane to remove impurities, wherein the impurities removed by filtering are substances larger than 0.25 micron, and the aperture of the filter membrane used for filtering is smaller than or equal to 0.25 micron; obtaining water extraction fine filtration liquid;
s4, filling and sterilizing: filling the water-extracted fine-filtered oxidized liquid obtained in the step S3 into 10-50 ml/per oral liquid bottle, and sterilizing at high temperature to obtain a finished product; the sterilization temperature in the filling sterilization is 104-128 ℃; the time is 10 to 90 minutes; the product is sterilized after being filled, so that the curative effect of the product during the shelf life is ensured.
The plant extract for treating tonsillitis and pharyngolaryngitis has application in preparing traditional Chinese medicines for treating tonsillitis and pharyngolaryngitis; can be used for treating tonsillitis and pharyngolaryngitis with good therapeutic effect.
Examples of the present invention are given below
Example 1
S1, cooked black sesame and salt composition: uniformly stirring the mixture of 5KG of black sesame and 0.3KG of salt, and frying the black sesame to obtain a cooked black sesame salt composition;
s2, extracting immersion liquid: mixing cooked black sesame 5KG salt 0.3KG composition, tea 0.2KG, licorice 0.1KG and water 20L, heating to 95 deg.c and extracting at constant temperature for 60 min to obtain water extract;
s3, filtering: filtering the water extract obtained in the step S1 through a filter membrane with the pore size of 0.25 micron to obtain water extraction fine filtrate;
s4, sterilization: filling the oxidized water extraction fine filtration oxidation liquid into each 50 ml oral liquid bottle and screwing the cover tightly; placing the filled bottles into a sterilization cabinet, heating to 108 ℃ and sterilizing for 30 minutes; obtaining finished plant extract for treating tonsillitis and pharyngolaryngitis;
through the operations, the obtained water extraction oral liquid of the cooked black sesame salt composition, the tea and the liquorice has obvious effect of treating tonsillitis and sphagitis.
The above description is only a preferred embodiment of the present invention, and not intended to limit the present invention, and the scope of the present invention is defined by the appended claims, and all changes that come within the meaning and range of equivalency of the specification are therefore intended to be embraced therein.
Claims (6)
1. A preparation method of plant extract for treating tonsillitis and pharyngolaryngitis is characterized by comprising the following steps:
s1, cooked black sesame and salt composition: stirring the mixture of black sesame and salt uniformly, and frying the black sesame to obtain a cooked black sesame salt composition;
s2, extracting immersion liquid: mixing cooked semen Sesami Niger and salt composition, folium Camelliae sinensis, Glycyrrhrizae radix, and water, and heating to obtain water extractive solution;
s3, filtering: filtering the water extract obtained in the step S2 by a filter membrane to remove impurities to obtain water extract fine filtrate;
s4, filling and sterilizing: and (5) filling the water-extracted fine-filtered liquid obtained in the step (S3) into an oral liquid bottle, and sterilizing at high temperature to obtain a finished product.
2. The method for preparing the plant extract for treating tonsillitis and pharyngolaryngitis according to claim 1, wherein the cooked black sesame salt composition of the extract of step S2: tea leaf: the weight ratio of water is as follows: 3-5: 1-3: 10-60, the heating extraction temperature is 90-100 ℃, and the extraction time is 30-100 minutes.
3. The method as claimed in claim 1, wherein the impurities removed by the filtration in step S3 are substances larger than 0.25 μm, and the pore size of the filtration membrane used for the filtration is smaller than or equal to 0.25 μm.
4. The method for preparing the plant extract for treating tonsillitis and pharyngolaryngitis according to claim 1, wherein the temperature for sterilization in the filling and sterilizing process of step S4 is 104-128 ℃; the time is 10-90 minutes.
5. The method for preparing a plant extract for the treatment of tonsillitis and pharyngolaryngitis according to claim 1, wherein said oral liquid bottle in the filling and sterilizing of step S4 has a volume of 10-50 ml/bottle.
6. The plant extract for treating tonsillitis and pharyngolaryngitis according to any one of claims 1-5, having application in preparing traditional Chinese medicine for treating tonsillitis and pharyngolaryngitis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010643875.9A CN111603525A (en) | 2020-07-08 | 2020-07-08 | Preparation method and application of plant extract for treating tonsillitis and pharyngolaryngitis |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010643875.9A CN111603525A (en) | 2020-07-08 | 2020-07-08 | Preparation method and application of plant extract for treating tonsillitis and pharyngolaryngitis |
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| CN111603525A true CN111603525A (en) | 2020-09-01 |
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| CN202010643875.9A Pending CN111603525A (en) | 2020-07-08 | 2020-07-08 | Preparation method and application of plant extract for treating tonsillitis and pharyngolaryngitis |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1235032A (en) * | 1998-05-09 | 1999-11-17 | 张玉国 | Chinese medicine for tonsillitis and laryngopharyngitis |
| CN104771629A (en) * | 2015-04-07 | 2015-07-15 | 陆开云 | Traditional Chinese medicine preparation used for treating pharyngitis |
| CN111166805A (en) * | 2020-03-20 | 2020-05-19 | 任秀江 | Preparation method and application of plant extract for treating tonsillitis and pharyngolaryngitis |
-
2020
- 2020-07-08 CN CN202010643875.9A patent/CN111603525A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1235032A (en) * | 1998-05-09 | 1999-11-17 | 张玉国 | Chinese medicine for tonsillitis and laryngopharyngitis |
| CN104771629A (en) * | 2015-04-07 | 2015-07-15 | 陆开云 | Traditional Chinese medicine preparation used for treating pharyngitis |
| CN111166805A (en) * | 2020-03-20 | 2020-05-19 | 任秀江 | Preparation method and application of plant extract for treating tonsillitis and pharyngolaryngitis |
Non-Patent Citations (4)
| Title |
|---|
| 中国疗养康复大辞典: "《中国疗养康复大辞典》", 30 June 1993, 中国广播电视出版社 * |
| 史德: "《盐醋葱姜蒜药用便方》", 30 April 2015, 金盾出版社 * |
| 吕志杰: "《伤寒杂病论研究大成 适合中医临床医师、医学生及中医爱好者阅读 第2版》", 30 September 2018, 中国医药科技出版社 * |
| 谭兴贵等: "《家庭常用食物食疗方》", 31 January 2004, 山东科学技术出版社 * |
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Application publication date: 20200901 |
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