CN1115977C - Method for preparing compound combined meilatuoning health food series - Google Patents

Abstract

The present invention relates to a preparation method of a compound composite Melatonin health-care food, and the compound combined Melatonin health-care food is composed of Melatonin, spirulina powder, pearl powder, pollen, etc. The pearl powder, the spirulina powder, the pollen, etc. are added to the Melatonin according to various proportions, and then the mixture is prepared into tablets or capsules by modern technology. When the mixture is prepared into liquor, functional oligosaccharide is added to the mixture, and the mixture can be prepared into various combined medicines. Various components have strong synergistic action on aging resistance, sleep promotion, sperm and bone enforcement and beauty treatment with the Melatonin. The Melatonin health-care food can replenish nutrients of hundreds of trace elements, activating enzymes, etc. for human bodies and simultaneously has various significant effects of loosening bowel to relieve constipation, regulating blood fat, etc.

Description

The compound combined Meilatuoning health food series preparation method

The invention belongs to field of health care food, be specifically related to a kind of compound combined Meilatuoning health food series preparation method.

On the at present domestic and international health food market, Meilatuoning [MELATONIN has another name called: epiphysin, melatonin etc.] is often seen based on the unitary agent of short sleep; And the function that has increased coordinating intestines and stomach, relaxed bowel in the second generation compound preparation (being that the Meilatuoning capsule adds short microecological balance liquor); But still be difficult to play the effect that significantly continues collaborative promotion health care because of lacking abundant nutritional supplement composition.

The object of the present invention is to provide a kind of health care advantage that can keep first generation Meilatuoning unitary agent, as: the control biological clock promotes sleep; The advantage that also can keep the compound preparation of the second generation as increasing Chinese medicine and nutrition prescription, has short microecological balance and relaxes bowel, gets rid of the effect of toxin; Can also in time remedy with supplemental treatment the elderly ubiquitously because of nutrients such as long-term calcium deficiency, zinc, iron, and the various serious illness that causes plays powerful health-care efficacy.

The present invention has been only because of having added the pearl powder that is described as east beauty treatment rarity in the prescription, thereby increased their synergy widely.Because pearl powder contains various trace elements such as the several amino acids of needed by human and iron, magnesium, zinc, sodium, be rich in the above calcium carbonate composition of 80-90% especially.So be again the good merchantable brand that the elderly replenishes the calcium.The informal dress pearl powder skin of moistening is built up health, is delayed senility.China's successive dynasties palace noble and modern age the famous person give pearl powder and preserve product on the appearance for normal.The successive dynasties well-known doctor is consistent to think that it has the arresting convulsion of calming the nerves, screen, the functions of detoxifying and promoting tissue regeneration of disappearing that make eye bright, and is applicable to: effects such as neurasthenia, insomnia, abscess of throat, gastric and duodenal ulcer and the burning hot wound of harnessing the river outward, wound convergence and skin softening and beautifying.And have ultra-fine because of it at present or the hydrolyzed pearl flour producing process, more improve the absorption of its effective ingredient, thereby produced more obvious effect.

Because of having added the nutritious spirulina composition, comprehensively work in coordination with health-care effect in the present invention's prescription thereby improved it widely.Because of spirulina is the super green health care food of a kind of alkalescent third generation.It can change the acidic constitution of human body into healthy alkalescent physique (blood pH 7.35-7.45), keeps the constant relatively of organismic internal environment.It does not have cell membrane, and the fibre-bearing element is not very easily absorbed by body.Spirulina contains hundreds of nutrition and bioactivator, thereby plays balanced nutritiously, improves the health-care effect of resistance against diseases, and its Main Ingredients and Appearance and function summarized introduction are as follows:

(1) vitamin: contained vitamin not only comprehensively but also abundant.1 gram spirulina vitamin content is equivalent to the content of 1000 gram common vegetables.Except that containing a large amount of vitamin Cs, folic acid, B family vitamin content is very abundant.Comprise that vitamin B1, B2, B3, B4, B5, B6, B12 and vitamin E, K1, K3 etc., particularly VB12 content are the twelvefolds (also Senior Three is doubly than pork liver) of animal food.And VE content is also more high than the content in the highest known Fructus Hordei Germinatus, and that VE not only has is anti-ageing, anti-oxidant, improve body's immunity, improves outside the microcirculation, suppresses the effect of growth of tumour cell in addition.

(2) mineral matter class: mineral matter is the important part of body tissue, plays very important function.Play an important role aspect Water-Electrolyte, acid-base balance, the reaction of nervimuscular irritability and the cardiac function keeping, and the metabolic function of body is also had a significant impact.Spirulina contains outside organic mineral matter, also contains inorganic salts and various trace element, as potassium, sodium, calcium, phosphorus, ammonium, zinc etc., and wherein the content of iron is 20 times of common food.Iron in the general food is gel hydroxide high ferro (ferric iron) and to contain iron in the spirulina be very easily absorbed ferrous (ferrous iron).In recent years, because of the teenager, particularly hypoferric anemia is very common in the middle and aged women.So in time use spirulina in the control malnutritional anemia, will play very significant effect.

(3) protein-based: as to contain the phytoprotein ratio in the spirulina up to 60-70%, have the laudatory title of 21st century protein.According to detection, (fat only 4%) exceeds nearly one times than the protein content of soybean to the hydrolysis of protein spirulina content of water content 5% up to 67%; Than beef, chicken Senior Three doubly, higher four times than thin pork, than high ten times in rice.The most important thing is that it contains the necessary several amino acids of human body.So spirulina deserves to be called human natural " treasure-house of protein ", and protein is origin of life, also is the basis of biological organs activity.

(4) fats: fat content is minimum in the spirulina, and the ratio of the unrighted acid that needed by human can't self synthesize again is higher.Clinical treatment proves that unrighted acid such as linoleic acid, leukotrienes etc. are the important component parts of forming cell, to making mitochondria and cell membrane particular importance, are the essential raw materials of synthetic phospholipid and prostatitis element, can promote to grow.Can also reduce fragility of blood vessels, pre-preventing thrombosis is playing a crucial role aspect cholesterol transport and the metabolism; This external enwergy promotes galactosis, sperm development etc.Particularly because spirulina is rich in r one linolenic acid (GLA) and helps fat metabolism, reduce cholesterol level, the prevention cholesterol condenses in blood vessel; Adjusting on the body's immunity, also can play an important role.So be the first-selected health food of high cholesterol people with hyperlipidemia.

(5) carbohydrate: the contained carbohydrate of spirulina is not a glucose, but glycogen.Human body very easily absorbs, and does not increase the weight of pancreas islet burden, and this is different from general vegetable food and enters very easily to pass on behind the body and be hepatic glycogen, when body needs, then discharges very soon.Having person to be " energy depot " of body, not only hypoglycemia, low blood pressure due to a variety of causes are had good action, to the diabetes patient, also is the food of unique supply human body energy, does not improve blood sugar level again.The supply that this can guarantee energy under the situation that strictness restriction glucose is taken in the needs of assurance organism metabolism, thereby reduces the acidosic generation of copper disease, so also be diabetes patient's excellent food.

(6) beta carotene: containing beta carotene in the spirulina than ten times of Senior Two in the carrot, also is that content is the highest in all foods.It can change vitamin A at liver, is the important source of body vitamin A.Vitamin A can promote the generation of various cells (as haemocyte, reproduction cell, epithelial cell) etc., quickens bone and forms, and to dental growth, keeps skin elasticity, promotes wound healing, and is also helpful.It can exempt to suffer from nyctalopia.It is again cellular metabolism and the requisite material of subcellular structure, and it also has antitumor action, can reduce the sensitiveness of body to carcinogen, suppress the growth of tumour cell, differentiation etc. are very easily poisoned but take a large amount of vitamin As merely, and so edible spirulina just this phenomenon can not occur.

(7) the blue or green class of algae: be the peculiar material of a kind of algae, rare by other plant, the effect that improves body's immunity and suppress growth of tumour cell is arranged, take so also be of value to tumour patient.

(8) chlorophyll: content is very abundant, for more than ten times of common vegetable, can promote human consumption, with the septicemia element, has non-specific anti-inflammatory, anti-allergic effects in the energy.In addition, stabilizing cell membrane is arranged still, the booster immunization function.So being of value to various gastritis patients takes.

(9) sulfuric acid ester: content is also higher, and anti-filterable virus effect is arranged, and the disease that virus is caused has supplemental treatment effect preferably; Be of value to taking of multiple hepatitis patient.

(10) ferment and enzyme: spirulina contains abundant multiple enzyme and a certain amount of enzyme element, can remove interior free yl, delays senility.Free radical can make dna damage, causes sudden change, can directly act on protein, makes it that cross-linked polymeric effect take place.And cell function is changed, oxygen acts on unrighted acid, generate lipid peroxide, it and combined with protein form compound and enter body, are difficult for being decomposed by enzyme or discharging, can accumulate and form a kind of sepia pigment granule, be commonly called as lipofuscin, this material may be aging relevant with tissue, but spirulina can be removed interior free yl, delaying senility course greatly.So middle-aged and old especially excellent health foods of renewing one's youth and prolonging life.

The present invention relaxes bowel because of having added pollen, having played again, gets rid of the effect of vivotoxin.And pollen can be divided into two types of melissa powder and pollen pinis at present.At first introduce the melissa powder: it is the male gamete of flowering plant, and the Source of life of plant is so also be human youth and healthy source.Nutritious extract Central China at this plant, amino acid whose content is beef, egg five to seven times, the content of nucleic acid is five to ten times of shrimp, the content of vitamin substantially exceeds any fruits and vegetables, active enzyme and trace element reach more than 107 kinds, are the most trustworthy natural nutrition health products of the mankind.Over the past thousands of years, countless examples show: edible melissa powder can make body obtain certain nutritional labeling and more functional component, thereby promote the normal growth of body to grow, metabolic turnover, improve the immunologic function of human body, make energeticly, appetite strengthens, muscle power endurance improves, and takes a certain amount of melissa powder every day and can reach the effect that delays senility and promote longevity.The effect of melissa powder can be summarized as following several respects:

(1) effect of beauty treatment is arranged.The women is after 30 years old, delicate skin begins to wear out, and particularly facial and the back of the hand easily produces freckle, foxiness etc., and this is that hypovitaminosis causes water metabolism bad, dry skin, the gloss elasticity attenuation cause the brown pigment deposition, and a lot of vitamin is water miscible, can not store in vivo, need to replenish everyday, can play cosmetic result so the cosmetics that contain vitamin are put on the skin on skin, but the effect that is coated with outside pure the dependence is small.And take the melissa powder everyday, outside interior supporting, the brown pigment deposition will disappear unconsciously, is " changing the preceding thousands of times of shape platform, not as informal dress melissa powder ".

(2) effect of fat-reducing is arranged.Because melissa powder content of cellulose is moderate, can reduce fat absorption after taking, and reaches the fat-reducing purpose.And, tend to make physique to weaken by going on a diet fat-reducing, and make skin ageing, and take the melissa powder, can impel muscle to increase, fat reduces, thereby makes the lath become strong and not fat, and this is the development trend that the human sciences loses weight, and is fashionable at present in generation.

(3) long-lived effect is arranged.The Caucasus region centenarian majority famous with " township of longevity " is the people of informal dress pollen.

(4) effect of curing the disease is arranged.The melissa powder is efficient more than 80% to treatment prostatitis and hypertrophy of the prostate, the effect that has other medicines to hardly match.The main component for the treatment of prostatitic medicine prostatitis health in fact, at present also is the melissa powder.In addition, the melissa powder all has magical effect to reducing blood lipid, treatment vascular diseases, diabetes, intractable constipation, atrophic gastritis, hepatitis.

(5) effect of diseases prevention is arranged.Because contain bioactive ingredients such as a large amount of nucleic acid, flavone compound, phytosterol in the melissa powder.Nucleic acid has cytophagous effect, makes to wear out and the sick cell disappearance, is updated to healthy new cell, thereby improves body's immunological function, and flavonoids has the effect of citrin sample, and energy softening blood vessel, phytosterol are the raw materials of manufacturing hormone in the human body.

And pollen pini is the pollen of pinaceae plant masson pine and Chinese pine, the unique in the world and pinaceae plant resource of the distinctive edibility pollen pini of China.Pollen pini is the spermatid of pine tree, is Source of life.In its flower core 48 hours at the beginning of being pollinated, the embryo can increase by 100,000 times, is the fastest a kind of of the known speed of expansion of living nature, and its secret is that pollen pini contains comprehensively and balanced active nutritional composition is natural miniature full nutrition treasure-house.Pollen pini is the present artificial pollen of gathering of unique in the world usefulness, has that Hua Yuan is single, quality is pure, and the non agricultural chemical residuum thing does not contain any zoohormone, is the pollen of only dietotherapeutic in the world.Put down in writing according to the Han dynasty Shennong's Herbal: " the pollen pini smell is sweet flat nontoxic, cures mainly trusted subordinate's fever and chills perverse trend, diuresis, and the hemostasis that disappears is obeyed the beneficial strength of making light of one's life by commiting suicide for a long time, prolongs life." the Tang Dynasty " Tang materia medica " states: " preserved egg is obeyed order for a long time and is made light of one's life by commiting suicide, and treats disease and surpasses skin, leaf and fat also." Ming Dynasty's Compendium of Material Medica claims: " preserved egg, sweet, warm, nontoxic, profit cardiopulmonary, beneficial gas; Dispel the wind hemostasis, also can make wine." because pollen pini has magical body-building function, the modern times have been classified as and respected monarch's tribute season.Modern science and technology research, confirmation pollen pini are rich in 200 multiple nutrients composition and active materials such as the necessary amino acid, vitamine of human body, mineral matter, enzyme, yellow cave class, nucleic acid, unrighted acid, polysaccharide.Science is measured, and its water-soluble amino acids is far above honeybee source pollen, and croude fatty acids content be three times of honeybee source pollen average of day this report, and the unrighted acid that helps controlling angiocardiopathy accounts for 72.5% of fatty acid total amount.Pollen pini nutrition is not only comprehensive but also composition is pure, and natural reasonable balanced collocation antagonism can not take place each other.It is active that the nutrition of pollen pini all belongs to, and for example, mineral matter wherein is not ionic condition all, but is combined in the amino acid, can needn't can directly be absorbed by the body through digestion in a short period of time.

The bata-carotene that contains in the pollen pini, micro-plain magnesium etc. have good opsonic action to people's incretory such as pituitary, thyroid gland, parathyroid gland, pancreas islet, sexual gland and thymus gland, can regulate the balance of internal system, improve the incretory situation, thereby some metabolic disorder that control is caused by endocrinopathy, as diabetes, butterfly macules, whelk, hyperthyroidism, prostate, illness, dysmenorrhoea, disorder of menstrual cycle, climacteric metancholia, neural inner feelings are weak, obesity, fatty liver, impotence etc.

The bata-carotene that enriches in the preserved egg pine; nutrients such as polysaccharose substance can protect human lymphocyte to escape injury, and rich in amino acid can promote leucocyte and T cell proliferation; and then activate whole immune system, make viral infringements such as human body is not subject to catch a cold, hepatitis.Selenium in the pollen pini, organized enzyme, biotin all are cancer-resisting substances, and they have coordinative role, improve immune function of human body, strengthen the detoxification ability of cell, strengthen the resistivity of body to carcinogenic factor, reach anti-cancer, anticancer purpose.And liver protection function arranged.

Materials such as the VE in the pollen pini, carrotene, selenium also have the lipofuscin, the free radical that obviously improve the interior SOD (superoxide dismutase) of body and can remove internal organs such as brain, the heart, liver, play delaying senility and the obvious anti-fatigue effect.

B family vitamin content in the pollen pini is very high, and the B family vitamin has many effects aspect beauty treatment.As B6: anti-antidandruff, prevent skin erosion, the lip drying.B ₂: the title of beauty treatment vitamin is arranged, and the active cell of energy prevents allergic, beautifies skin.The B family vitamin matches with vitamin C, E, can eliminate melanin in the skin, safeguard the pure white beauty of skin.Therefore, the cosmetic result of pollen pini really is from inside to outside, and the combination of inner and outside brings basic variation.

In the pollen pini because of being rich in water-soluble amino acids, croude fatty acids, unrighted acid, r leukotrienes, vitamin and trace element etc. can guarantee the growth needs of brain cell, and the brain cell cynapse is prolonged, and the contact between the nerve cell is strengthened, the transmission of information is more rapid, make the increased functionality of brain, memory improves.And can prevent senile dementia.

Contained VC, VE, selenium, magnesium, yellow cave class material in the pollen pini can obviously reduce blood fat, cholesterol, regulate the endocrine of human body, keep normal arterial pressure, strengthen vessel wall elasticity, improve the microcirculation of heart and brain, thereby effectively prevent the generation of cardiovascular and cerebrovascular disease.

Pollen pini contains nearly hundred kinds of enzymes, can promote gastrointestinal peristalsis, improves a poor appetite and helps digest; Gastrointestinal dysfunction disease there is tangible regulating action.Contain various active amino acid in the pollen pini, needn't and decompose through digestion after the food, can directly be absorbed by the body, arrive ulcer spot, go to carry out tissue repair, also have plurality of enzymes and coenzyme, also the utmost point is of value to this reparation.

Pollen pini also is of value to and improves constipation, promotes hematopoietic function, by increasing red blood cell, and useful enriching blood and effect such as healthy hair.

During as needs preparations oral liquid formulation, both mouthfeel was good for ease of producing, and the product that eats of diabetic, adiposis patient and hypoglycemia patient is used the functional oligose composition so add, as best flavor enhancement again.Functional oligose comprises: stachyose, raffinose, milk ketose, FOS, xylo-oligosaccharide, galactooligosaccharide, oligoisomaltose and soyabean oligosaccharides etc.Its major physiological function comprises following four aspects:

(1) be difficult to or do not absorbed by human consumption, the energy value that is provided is very low or do not have at all.Can play a role in low-energy food, satisfy those to greatest extent and liked sweets to worry the person's of getting fat requirement again, also can supply the diabetes patient, adiposis patient and hypoglycemia patient are edible.

(2) Bifidobacterium and promote its growth and breeding in the activation enteron aisle, Bifidobacterium is the beneficial bacterium in the human body intestinal canal, its bacterium number can reduce gradually with the increase at age.And by taking in the ability that accrues that functional oligose can promote Bifidobacterium in the enteron aisle.

(3) can not cause that the tooth dental caries become, and help keeping oral hygiene.Therefore functional oligose can not cause carious tooth because of not being the substrate of the suitable effect of microorganism in the oral cavity, and safe proterties is good.

(4) functional oligose belongs to water-soluble dietary fiber, is difficult for or is not absorbed, therefore has the part physiological function of dietary fiber by human consumption, as reducing serum cholesterol and prevention colon cancer etc.

The invention has the advantages that:

(1) because of after in single Meilatuoning, adding pearl powder, spirulina and pollen, and by the nutrition of abundant human body inherence is provided, make Meilatuoning regulate the full-scope safeguards that major function aspect the biological clock has had material.And meeting thereby play the obvious synergistic effect, strengthened whole effect greatly.

(2) this prescription also can be made into oral liquid and except that the whole advantages that keep like product, the effects such as beneficial brain and lipopenicillinase beauty treatment of significantly replenishing the calcium can also be arranged.

(3) again because of this prescription being made capsule or tablet, be convenient to the packing and carry, event can conveniently be transported and the consumer takes.

(4) the particularly design of A+B combination dosage forms, can avoid because of the difficult deficiency of taking Meilatuoning by day of some occupation, and can satisfy those special needs to greatest extent and improve nutrition, eliminate tired, strengthen immunity of organisms, the elderly's of supplemental treatment various diseases common requirements.

Prescription of the present invention is mainly by Meilatuoning (MELATONIN), pearl powder, and spirulina, pollen pini or melissa powder reach compositions such as adding an amount of functional oligose in case of necessity again.

Its prescription mainly contains following several:

(1) four unification formulation: pollen pini adds pearl powder and adds spirulina powder and Meilatuoning and excipient and make tablet or capsule.Its ratio is pollen pini 20-80%, pearl powder 5-30%, spirulina powder 20-80%, Meilatuoning 0.001-1%.

(2) A+B closes clothes () formulation: the A. type---and pollen pini adds pearl powder and spirulina powder and excipient and makes tablet or capsule; Its ratio is pollen pini 20-80%, pearl powder 5-30%, spirulina powder 20-80%; Type B-Meilatuoning adds excipient and makes tablet capsule; Its ratio is: Meilatuoning 0.01-3%, all the other are excipient.

(3) A+B closes clothes (two) formulation: the A type---and loose medicinal powder adds spirulina powder and excipient is made tablet or capsule; Its ratio is pollen pini 20-80%, spirulina powder 20-80%; Type B-Meilatuoning adds pearl powder and excipient is made tablet or capsule; Its ratio is: Meilatuoning 0.001-3%, pearl powder are 90-100%.

(4) A type oral solutions+B tablet or capsule close clothes () formulation: the A type---and pollen pini adds pearl powder and spirulina powder and functional oligose flavor enhancement and makes oral liquid; Its ratio is: pollen pini 20-80%, pearl powder 5-30%, spirulina powder 20-80%, functional oligose 1-20%; Type B-Meilatuoning adds excipient and makes tablet or capsule; Its ratio is: Meilatuoning 0.01-3%, all the other are excipient.

Pearl powder in the former four flavor combinations is deducted, form and keep Meilatuoning and spirulina powder and pollen pini three flavor Main Ingredients and Appearances.Its prescription has following three kinds:

A) three-in-one formulation (): pollen pini adds spirulina powder and Meilatuoning and excipient and makes tablet or capsule; Its ratio is: pollen pini 20-80%, spirulina powder 20-80% Meilatuoning 0.001-1%.

B) A+B closes clothes (three) formulation: A type-pollen pini is made tablet or capsule after adding spirulina powder and excipient; Its ratio is: pollen pini 20-80%, spirulina powder 20-80%; Type B-Meilatuoning adds excipient and makes tablet or capsule; Its ratio is: Meilatuoning 0.01-3%, all the other are excipient.

C) .A oral liquid+B tablet or capsule close clothes (two) formulation: A type-pollen pini adding spirulina powder adds the functional oligose flavor enhancement again and makes oral liquid; Its ratio is: pollen pini 20-80%, spirulina 20-80%, functional oligose 1-20%; Type B-Meilatuoning adds excipient and makes tablet or capsule; Its ratio is: Meilatuoning 0.01-3%, all the other are excipient.

(6) spirulina powder in the former four flavor combinations is deducted and keep Meilatuoning and pollen pini and pearl powder three flavor Main Ingredients and Appearances and form.Its prescription has following three kinds:

A) three-in-one formulation (two): pollen pini adds pearl powder and Meilatuoning and excipient and makes tablet or capsule; Its ratio is: pollen pini 70-98% pearl powder 1-30%, Meilatuoning 0.001-1%.

B) A+B closes clothes (four) formulation: A type-pollen pini is made tablet or clear and bright capsule after adding pearl powder and excipient; Its ratio is: pollen pini 70-99%, pearl powder 1-30%; Type B-Meilatuoning adds excipient and makes tablet or capsule; Its ratio is: Meilatuoning 0.01-3%, all the other are excipient.

C) .A oral liquid+B tablet or capsule close clothes (three) formulation: A type-pollen pini is made oral liquid after adding pearl powder and functional oligose flavor enhancement; Its ratio is: pollen pini 70-90%, pearl powder 1-30%, functional oligose 1-20%; Type B-Meilatuoning adds excipient and makes tablet or capsule; Its ratio is: Meilatuoning 0.01-3%, all the other are excipient.

(7) pollen pini in the former four flavor combinations is deducted, form and only keep Meilatuoning and spirulina powder and pearl powder three flavor Main Ingredients and Appearances.Its prescription has following three kinds:

A) three-in-one formulation (three): spirulina powder is made tablet or capsule after adding pearl powder and Meilatuoning and excipient, and its ratio is: spirulina 70-98%, pearl powder 1-30%, Meilatuoning 0.001-1%.

B) A+B closes clothes (five) formulation: A type-spirulina powder is made tablet or capsule after adding pearl powder and excipient: its ratio is: spirulina powder 70-98%, pearl powder 1-30%, Type B-Meilatuoning adds excipient and makes tablet or capsule, its ratio is: Meilatuoning 0.01-3%, all the other are excipient.

C) A oral liquid+B tablet or capsule close clothes (four) formulation: A type-spirulina powder is made oral liquid after adding pearl powder and functional oligose flavor enhancement; Its ratio is: spirulina powder 70-98%, pearl powder 1-30%, functional oligose 1-20%; Type B-Meilatuoning is made tablet or capsule after adding excipient; Its ratio is: Meilatuoning 0.01-3%, all the other are excipient.

(8) A+B+C+D closes oral dosage form: A type-Meilatuoning is made tablet or capsule after adding excipient, and its ratio is: 0.01-3%, and all the other are excipient; Type B-pollen pini adds excipient and makes tablet or capsule, and its ratio is 90-100%, and all the other are excipient; C type-spirulina powder adds excipient; Make tablet or capsule, its ratio is: 90-100%; D type-pearl powder adds excipient and makes tablet or capsule, and its ratio is 90-100%, and all the other are excipient.

More than all places with pollen pini, all can adopt the melissa powder to substitute.Also pollen pini and melissa powder can be share, the dosage complementation, and it is constant to account in total prescription percentage.

Now technological process is expressed as follows:

(1) composite tablet technological process:

---------------------------------compressing tablet---polishes (coating or dressing)---packing---irradiation sterilization-check---label---finished product to the lubricant mixing to whole grain to the system wet granular to the system softwood to pollen class raw material in oven dry to add wetting agent or adhesive to mix stirring to add other supplementary material (can contain one or more compositions such as superfine pearl powder, spirulina powder, Meilatuoning by different formulations) in oven dry (pulverizing) in selected check.

(2) single tablet technological process:

------------------------polishing (coating or dressing)---is packed---irradiation sterilization---check---finished product to compressing tablet to the lubricant mixing to whole grain to the system wet granular in oven dry to make softwood to add excipient such as starch for various single raw materials or the peaceful raw material of U.S. position holder.

(3) compound oral liquid technological process:

---selected check---fermentation---extract (concentrating)---adds other supplementary material (press different formulations, can contain in hydrolysis pearl, enzymolysis spirulina and Meilatuoning, the functional oligose one or more)---filters that---------lamp is examined and chemically examined---label---packed products in sterilization in embedding to pollen class raw material.

(4) compound capsule agent technological process:

---selected---oven dry (pulverizings)---adds and joins other supplementary material (contain in superfine pearl powder, spirulina powder, the Meilatuoning etc. one or more) and---mix and stir that---------packing is---auxilliary according to---check---finished product of sterilizing for filled capsules in oven dry pollen class raw material.

(5) single capsule technological process:

Various single raw materials or Meilatuoning raw material---add excipient such as starch and---mix and stir---oven dry---filled capsules---packing---radiation sterilization---check---finished product.

Its instructions about how to take medicine: whenever last just before going to bed hour of single Meilatuoning usual amounts clothes 1-3mg, the age more than 60 years old or serious insomnia person rise to more than the 6mg; Tumour patient can be obeyed more than the 9mg maximum every days.All various compound formulations that contain the Meilatuoning composition, its consumption, all be no more than Meilatuoning the day/time the sum total dosing be standard.The consumption of other pollen, spirulina, pearl powder single or compound mixture, as every specification is 0.3g-0.5g, but then every day breakfast, lunch and dinner, half an hour ante cibum or add and respectively obey the 3-6 sheet just before going to bed, A type oral liquid at every turn just before going to bed with Type B Meilatuoning tablet or capsule with clothes 25cc; All serious constipation or patients such as extremely tired person or tumour, all multiplicable taking dose.

Now the first Example formulations technological process is done further to comment:

Four unification formulations: pollen pini is through selected---oven dry---and adding superfine pearl powder and spirulina powder and Meilatuoning-mixing stirs---glue capsule (oven dry) or film-making agent: [add adhesive---the system soft material---make wet granular---oven dry---whole grain---the lubricant mixing---compressing tablet---polishing (coating or dressing)]---packing---irradiation sterilization---check---label---finished product.Every weighs 0.3g-0.5g, pollen pini 0.1g-0.2g, spirulina powder 0.1g-0.2g, pearl powder 0.05g-0.1g, Meilatuoning 0.3mg-0.5mg.

The second Example formulations technological process is described in further detail: A+B contains clothes () formulation: the A type again---and pollen pini is through selected---oven dry---add superfine pearl powder and spirulina powder---mixing is stirred---glue capsule (oven dry) or film-making agent: [add adhesive---the system soft material---make wet granular---oven dry---whole grain is even---compressing tablet (adding the lubricant mixing)---polishing (coating or dressing)]---packing---irradiation sterilization---check---label---finished product.Contain pollen pini 0.1g-0.2g, pearl powder 0.05g-0.1g, spirulina powder 0.1g-0.2g among every heavy 0.3g-0.5g; Type B---Meilatuoning adds excipient such as starch---glue capsule (oven dry) or film-making agent: [add adhesive---the system soft material---make wet granular---oven dry---whole grain is even---compressing tablet (adding the lubricant mixing)---polishing (coating packing)]---irradiation sterilization---check---finished product.Contain Meilatuoning 1-9mg among every heavy 0.3-0.4g.

The 3rd Example formulations technological process is described in further detail: A+B closes clothes (two) formulation: the A type again---pollen pini is through selected---oven dry---add spirulina powder---mix stir---glue capsule (oven dry) or film-making agent; [add adhesive---the system soft material---the system wet granular---oven dry---whole evenly sticking---compressing tablet (adding the lubricant mixing)---polishing (coating or dressing)]---packing---irradiation sterilization---check---finished product.Containing pollen pini 0.1g-0.25g, spirulina powder 0.1g-0.25g among every 0.3g-0.5g, Type B---Meilatuoning adds superfine pearl powder---and mixing is stirred---glue capsule (oven dry) or film-making agent: [add adhesive---the system soft material---make wet granular---oven dry---whole grain is even---compressing tablet (adding the lubricant mixing)---polishing (coating dressing)]---packing---irradiation sterilization---check---finished product.Contain Meilatuoning 0.1-1mg pearl powder 0.25g-0.5g among every 0.3g-0.5g.

The 4th Example formulations technological process is described in further detail: A oral liquid+B tablet or capsule close clothes () formulation: the A type again, and---the pollen pini raw material---------extract (concentrating) and---add hydrolyzed pearl powder and enzymolysis spirulina and soyabean oligosaccharides seasoning and---filter---embedding---sterilization---lamp inspection and chemical examination---label---packing---finished product in selected check by fermentation.Containing pollen pini composition ratio among every 25cc is that 30-45%, hydrolyzed pearl powder ratio are that 5-20%, enzymolysis spirulina ratio are that 30-45%, soyabean oligosaccharides ratio are 5-20%.Type B---Meilatuoning adds tax row agent such as starch---glue capsule (oven dry) or film-making agent: [add adhesive---the system soft material---make wet granular---oven dry---whole is evenly---compressing tablet (adding the lubricant mixing)---polishing (coating or dressing)]-packing---irradiation sterilization---check---finished product.Contain Meilatuoning 1-9mg in every.

Specific embodiment can be according to the plus-minus of composition, change many series prescriptions and process scheme, if follow in the literary composition same or similar this serial protection domain that all belongs to of (1)-(8) of lifting kind formulation.

Claims (4)

1, a kind of preparation method of compound Meilatuoning health food capsule is characterized in that: with pollen pini class raw material, selected, pulverize, the oven dry back adds superfine pearl powder, spirulina powder, Meilatuoning mixing stirring, oven dry, filled capsules; The consumption of each raw material is for containing pollen pini 20-80%, pearl powder 5-30%, spirulina 20-80%, Meilatuoning 0.001-1%; Each raw material consumption sum is 100%.

2, a kind of preparation method of compound Meilatuoning health food tablet is characterized in that: with pollen pini class raw material, selected check, pulverizing, dry, add and join other supplementary material: wetting agent or adhesive, system soft material, system wet granular, oven dry, whole grain, lubricant mixing, compressing tablet, polishing, packing are stirred, add in superfine pearl powder, spirulina powder, Meilatuoning, mixing; The consumption of each raw material is: pollen pini 20-80%, pearl powder 5-30%, spirulina powder 20-80%, Meilatuoning 0.001-1%; Each raw material consumption sum is 100%.

3, compound Meilatuoning health food preparation method according to claim 1 and 2; It is characterized in that, add an amount of functional oligose composition.

4, compound Meilatuoning health food preparation method according to claim 1 and 2 is characterized in that, the pollen pini composition is by melissa powder or melissa powder and the complementary mixture replacing of pollen pini, and consumption is 20-80%.