CN111562203A - 来自小样品体积的成形血液组分沉降速率的快速测量 - Google Patents

来自小样品体积的成形血液组分沉降速率的快速测量 Download PDF

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Publication number
CN111562203A
CN111562203A CN202010107295.8A CN202010107295A CN111562203A CN 111562203 A CN111562203 A CN 111562203A CN 202010107295 A CN202010107295 A CN 202010107295A CN 111562203 A CN111562203 A CN 111562203A
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CN
China
Prior art keywords
sample
centrifuge
hematocrit
sedimentation
blood
Prior art date
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Pending
Application number
CN202010107295.8A
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English (en)
Chinese (zh)
Inventor
M·戴耶尔
S·阿内卡尔
E·霍姆斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Theranos Inc
Original Assignee
Theranos Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theranos Inc filed Critical Theranos Inc
Publication of CN111562203A publication Critical patent/CN111562203A/zh
Pending legal-status Critical Current

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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D21/00Separation of suspended solid particles from liquids by sedimentation
    • B01D21/30Control equipment
    • B01D21/32Density control of clear liquid or sediment, e.g. optical control ; Control of physical properties
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D21/00Separation of suspended solid particles from liquids by sedimentation
    • B01D21/26Separation of sediment aided by centrifugal force or centripetal force
    • B01D21/262Separation of sediment aided by centrifugal force or centripetal force by using a centrifuge
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D21/00Separation of suspended solid particles from liquids by sedimentation
    • B01D21/30Control equipment
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04Investigating sedimentation of particle suspensions
    • G01N15/05Investigating sedimentation of particle suspensions in blood
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/491Blood by separating the blood components
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5021Test tubes specially adapted for centrifugation purposes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04Investigating sedimentation of particle suspensions
    • G01N15/05Investigating sedimentation of particle suspensions in blood
    • G01N2015/055Investigating sedimentation of particle suspensions in blood for hematocrite determination

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Ecology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
CN202010107295.8A 2014-01-22 2015-01-22 来自小样品体积的成形血液组分沉降速率的快速测量 Pending CN111562203A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461930432P 2014-01-22 2014-01-22
US61/930,432 2014-01-22
CN201580015419.7A CN106170696B (zh) 2014-01-22 2015-01-22 来自小样品体积的成形血液组分沉降速率的快速测量

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201580015419.7A Division CN106170696B (zh) 2014-01-22 2015-01-22 来自小样品体积的成形血液组分沉降速率的快速测量

Publications (1)

Publication Number Publication Date
CN111562203A true CN111562203A (zh) 2020-08-21

Family

ID=53681947

Family Applications (2)

Application Number Title Priority Date Filing Date
CN202010107295.8A Pending CN111562203A (zh) 2014-01-22 2015-01-22 来自小样品体积的成形血液组分沉降速率的快速测量
CN201580015419.7A Active CN106170696B (zh) 2014-01-22 2015-01-22 来自小样品体积的成形血液组分沉降速率的快速测量

Family Applications After (1)

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CN201580015419.7A Active CN106170696B (zh) 2014-01-22 2015-01-22 来自小样品体积的成形血液组分沉降速率的快速测量

Country Status (6)

Country Link
EP (1) EP3097415A4 (es)
JP (3) JP2017504027A (es)
CN (2) CN111562203A (es)
CA (1) CA2936828A1 (es)
MX (2) MX2016009516A (es)
WO (1) WO2015112768A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106446582A (zh) * 2016-10-18 2017-02-22 江西博瑞彤芸科技有限公司 图像处理方法
GB2555402B (en) * 2016-10-24 2019-10-23 Entia Ltd A system and method for fluid analysis
WO2018132619A1 (en) * 2017-01-11 2018-07-19 Hemodus Medical, Llc Method of estimating blood volume
JP7037324B2 (ja) * 2017-01-27 2022-03-16 日本光電工業株式会社 炎症マーカー測定方法、炎症マーカー測定装置、炎症マーカー測定プログラム、および当該プログラムを記録した記録媒体
NO346147B1 (en) * 2017-11-09 2022-03-21 Spinchip Diagnostics As Method and apparatus for controlling a focus point of stationary beam focusing on a sample in a rotating cartridge placed in a rotating disc
GB2573126B (en) * 2018-04-24 2022-11-09 Entia Ltd A method and apparatus for determining haemoglobin concentration
EP3820589B1 (en) * 2018-07-09 2023-08-30 Laboratory Corporation of America Holdings Devices and methods for plasma separation and storage
CN111198262B (zh) * 2018-11-19 2023-04-11 苏州迈瑞科技有限公司 一种用于尿液有形成分分析仪的检测装置及方法
JP7413692B2 (ja) 2019-09-25 2024-01-16 東ソー株式会社 細胞を含む試料の前処理方法
CN111537409B (zh) * 2020-05-06 2022-10-14 南京邮电大学 一种高精度血沉温度补偿测量方法与装置

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996039618A1 (en) * 1995-06-06 1996-12-12 Brigham And Women's Hospital Determining erythrocyte sedimentation rate and hematocrit
EP1063513A2 (en) * 1999-06-22 2000-12-27 Wardlaw, Stephen Clark Method and apparatus for timing intermittant illumination of a sample tube positioned on a centrifuge platen and for calibrating a sample tube imaging system
EP1063515A2 (en) * 1999-06-25 2000-12-27 Wardlaw, Stephen Clark Rapid method for determining the erythrocyte sedimentation rate in a sample of anticoagulated whole blood
US6403328B1 (en) * 1998-03-05 2002-06-11 Roger Clampitt Method of measuring erythrocyte sedimentation rate (ESR) or plasma fibrinogen of a blood sample
US20130078733A1 (en) * 2011-09-25 2013-03-28 Theranos, Inc., a Delaware Corporation Systems and methods for fluid handling

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4197735A (en) * 1978-11-06 1980-04-15 Chase Instruments Corporation Blood sedimentation rate test means
CA2230222A1 (en) * 1997-03-10 1998-09-10 Stephen C. Wardlaw Method and assembly for rapid measurement of cell layers
CN1256587C (zh) * 2004-05-31 2006-05-17 苏州市第二人民医院 血液流变全血质控物及其制备方法
ITUD20050118A1 (it) * 2005-07-13 2007-01-14 Sire Analytical Systems Srl Procedimento per la taratura di macchine per l' analisi di parametri del sangue connessi alla densita' del sangue, quali la velocita' di eritrosedimentazione e/o di aggregazione dei globuli rossi
US20110226045A1 (en) * 2009-11-25 2011-09-22 Mcquillan Adrian Charles Liquid analysis system

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996039618A1 (en) * 1995-06-06 1996-12-12 Brigham And Women's Hospital Determining erythrocyte sedimentation rate and hematocrit
US6403328B1 (en) * 1998-03-05 2002-06-11 Roger Clampitt Method of measuring erythrocyte sedimentation rate (ESR) or plasma fibrinogen of a blood sample
EP1063513A2 (en) * 1999-06-22 2000-12-27 Wardlaw, Stephen Clark Method and apparatus for timing intermittant illumination of a sample tube positioned on a centrifuge platen and for calibrating a sample tube imaging system
EP1063515A2 (en) * 1999-06-25 2000-12-27 Wardlaw, Stephen Clark Rapid method for determining the erythrocyte sedimentation rate in a sample of anticoagulated whole blood
US6204066B1 (en) * 1999-06-25 2001-03-20 Robert A. Levine Rapid method for determining the erythrocyte sedimentation rate in a sample of anticoagulated whole blood
US20130078733A1 (en) * 2011-09-25 2013-03-28 Theranos, Inc., a Delaware Corporation Systems and methods for fluid handling

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
YVES PAWLOTSKY ET AL.: "An Erythrocyte Sedimentation Rate Adjusted for the Hematocrit and Hemoglobin Concentration", 《AMERICAN SOCIETY FOR CLINICAL PATHOLOGY》 *

Also Published As

Publication number Publication date
MX2021013459A (es) 2021-12-10
WO2015112768A1 (en) 2015-07-30
CN106170696B (zh) 2020-03-20
MX2016009516A (es) 2016-10-26
EP3097415A4 (en) 2017-11-29
CA2936828A1 (en) 2015-07-30
EP3097415A1 (en) 2016-11-30
JP2020046442A (ja) 2020-03-26
CN106170696A (zh) 2016-11-30
JP2017504027A (ja) 2017-02-02
JP2022043307A (ja) 2022-03-15

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