CN111514225A - Traditional Chinese medicine composition for treating haemorrhoids and preparation method and application thereof - Google Patents

Traditional Chinese medicine composition for treating haemorrhoids and preparation method and application thereof Download PDF

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CN111514225A
CN111514225A CN202010474728.3A CN202010474728A CN111514225A CN 111514225 A CN111514225 A CN 111514225A CN 202010474728 A CN202010474728 A CN 202010474728A CN 111514225 A CN111514225 A CN 111514225A
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traditional chinese
chinese medicine
medicine composition
hemorrhoids
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杨德开
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11—Pteridophyta or Filicophyta (ferns)
    • A61K36/12—Filicopsida or Pteridopsida
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/42—Cucurbitaceae (Cucumber family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488—Pueraria (kudzu)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534—Mentha (mint)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

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  • Alternative & Traditional Medicine (AREA)
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  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Medicines Containing Plant Substances (AREA)

Abstract

The invention provides a traditional Chinese medicine composition for treating hemorrhoids and a preparation method and application thereof, belonging to the technical field of traditional Chinese medicines, wherein the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 15-40 parts of rheum officinale, 15-40 parts of rhizoma paridis, 15-40 parts of momordica grosvenori, 15-30 parts of kudzuvine leaf, 15-30 parts of sijichun, 15-30 parts of mint and 15-30 parts of pteris latifolia. The traditional Chinese medicine composition can clear away heat and toxic materials, remove stasis and relieve swelling, and has the effects of quick response, short treatment course and no relapse after healing when treating hemorrhoids.

Description

Traditional Chinese medicine composition for treating haemorrhoids and preparation method and application thereof
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating hemorrhoids.
Background
Hemorrhoid is a common disease located at the anus, is generally considered to be formed when anus cushion tissues are abnormal and have symptoms, and has the characteristic of high morbidity among people.
Except for surgical excision, most of the existing hemorrhoids are treated by medicines, and the traditional Chinese medicines are mostly used in the medicine treatment, but most of the existing traditional Chinese medicine compositions for treating hemorrhoids have the defect of long treatment period.
Disclosure of Invention
Based on the background problems, the invention aims to provide the traditional Chinese medicine composition for treating the hemorrhoids, which has the effects of short treatment course and no relapse after healing; the invention also aims to provide a preparation method and application of the traditional Chinese medicine composition for treating hemorrhoids.
On one hand, the embodiment of the invention provides a traditional Chinese medicine composition for treating hemorrhoids, which comprises the following raw materials in parts by weight:
15-40 parts of rheum officinale, 15-40 parts of rhizoma paridis, 15-40 parts of momordica grosvenori, 15-30 parts of kudzuvine leaf, 15-30 parts of sijichun, 15-30 parts of mint and 15-30 parts of pteris latifolia.
In one embodiment, the traditional Chinese medicine composition for treating hemorrhoids comprises the following raw materials in parts by weight:
20-30 parts of rheum officinale, 20-30 parts of rhizoma paridis, 20-30 parts of momordica grosvenori, 18-20 parts of kudzuvine leaf, 18-20 parts of sijichun, 18-20 parts of mint and 18-20 parts of pteridium aquilinum.
The effects of the raw materials selected in the embodiment of the invention are as follows:
rhubarb root: the rhubarb contains chrysophanol, emodin, physcion, aloe-emodin and other components, anthraquinone glycoside, rumicin, 6-O-malonyl, -beta-methyl, -D-pyran, glucose, glycoside aspartame, and other components, and has the functions of clearing away heat and toxic material, cooling blood and stopping bleeding, eliminating blood stasis and swelling, relaxing bowels and killing pests; the main treatment is as follows: pulmonary tuberculosis hemoptysis, pulmonary abscess, hematemesis, blood stasis abdominal pain, traumatic injury, constipation, mumps, carbuncle sore pyogenic infections, scald, scabies tinea, eczema.
Rhizoma paridis: has effects of clearing away heat and toxic materials, relieving swelling and pain, cooling liver, and arresting convulsion; the main treatment is as follows: furuncle, carbuncle and swelling, swollen and sore throat, snake and insect bite, traumatic injury, pain, convulsion and convulsion.
Momordica grosvenori: has effects of clearing heat, moistening lung, relieving sore throat, relieving constipation; the main treatment is as follows: cough due to lung heat, pharyngalgia, aphonia, constipation due to intestinal dryness.
Kudzu leaf: mainly used for stopping bleeding of incised wound.
Spring in four seasons: clearing heat, diminishing inflammation, calming the liver and purging fire; the main treatment is as follows: acute infectious icterohepatitis.
Mint: disperse wind-heat, clear head and eyes, promote eruption; the main treatment is as follows: wind-heat type common cold, initial wind-warm syndrome, headache, conjunctival congestion, sore throat, aphtha, rubella, measles, and chest and hypochondrium distention and fullness.
Pteris latifolius: herba Pteridis Dactylinae, herba Potentillae Discoloris, herba Pteridis Latifoliae, radix seu folium Psychotriae Rubrae, herba Dendrobii, herba Botrychii Divaricati, and radix seu caulis Jasmini Lanceolarii; clearing away heat and toxic materials; nourishing; relieving cough and asthma; mainly treats venomous snake bite; acute mastitis; furuncle swelling toxin; scrofula; laryngopharyngitis; cough and dyspnea due to lung heat.
The anal pad is provided with abundant veins which are technically called as venous plexuses, the venous plexuses are special, the venous valves are not arranged inside the anal pad and are positioned at the lowest part of the abdominal cavity and the pelvic cavity, and surrounding tissues are loose, so that the venous plexuses are easy to be congested and stagnant, and then, the venous plexuses are subjected to pressure due to the fact that the venous walls are stressed for a long time to form varicose veins; if the factors of long-term sitting and standing, constipation, pregnancy, prostatic hyperplasia, liver cirrhosis and pelvic tumor exist, varicose veins are caused, and hemorrhoids are formed. Therefore, the invention adopts the rhubarb root, the paris polyphylla and the momordica grosvenori as monarch drugs, has the effects of clearing away heat and toxic materials, removing stasis and relieving swelling, treats hemorrhoids symptomatically more accurately and has the effects of quick effect, short treatment course and no relapse.
On the other hand, the embodiment of the invention provides a preparation method of the traditional Chinese medicine composition for treating hemorrhoids, which comprises the following steps: grinding and sieving the raw materials respectively to obtain medicinal powder, and mixing the medicinal powder according to the raw material proportion to obtain the traditional Chinese medicine composition.
In one embodiment, the feedstock is ground and passed through a 60-80 mesh screen.
On the other hand, the embodiment of the invention also provides application of the traditional Chinese medicine composition for treating the haemorrhoids in preparation of a medicine for treating the haemorrhoids.
Preferably, the medicament for treating the hemorrhoids is an external preparation, and the external preparation is an ointment, a suppository or a spray.
Compared with the prior art, the invention has the following effects:
the traditional Chinese medicine composition disclosed by the invention has the effects of clearing away heat and toxic materials, removing stasis and relieving swelling, and has the effects of taking effect quickly, being short in treatment course and preventing recurrence after healing when being used for treating hemorrhoids.
Detailed Description
The invention provides a traditional Chinese medicine composition for treating hemorrhoids, which comprises the following raw materials in parts by weight:
15-40 parts of rheum officinale, 15-40 parts of rhizoma paridis, 15-40 parts of momordica grosvenori, 15-30 parts of kudzuvine leaf, 15-30 parts of sijichun, 15-30 parts of mint and 15-30 parts of pteris latifolia.
The invention adopts the rhubarb root, the paris polyphylla and the momordica grosvenori as monarch drugs, has the effects of clearing away heat and toxic materials, removing stasis and relieving swelling, treats hemorrhoids symptomatically more accurately, and has the effects of quick effect, short treatment course and no recurrence.
The invention will be elucidated by means of specific embodiments.
Example 1
A traditional Chinese medicine composition for treating hemorrhoids comprises the following raw materials in parts by weight: 40g of rheum officinale, 15g of rhizoma paridis, 20g of momordica grosvenori, 15g of folium puerariae, 18g of sijichun, 30g of mint and 15g of pteridium aquilinum.
The preparation method of the traditional Chinese medicine composition for treating hemorrhoids comprises the following steps:
1. grinding the above components respectively and sieving with 60 mesh sieve to obtain medicinal powder; weighing the medicinal powders according to the proportion, and uniformly mixing for later use;
2. mixing the mixed medicinal powder with tung oil at a mass ratio of 1:2, stirring and concocting into paste.
Example 2
A traditional Chinese medicine composition for treating hemorrhoids comprises the following raw materials in parts by weight: 15g of rheum officinale, 40g of rhizoma paridis, 15g of momordica grosvenori, 30g of kudzuvine leaf, 15g of sijichun, 15g of mint and 30g of pteris latiusculi. The preparation method of the traditional Chinese medicine composition for treating hemorrhoids in the embodiment is the same as that in the embodiment 1.
Example 3
A traditional Chinese medicine composition for treating hemorrhoids comprises the following raw materials in parts by weight: 20g of rheum officinale, 20g of rhizoma paridis, 20g of momordica grosvenori, 20g of kudzuvine leaf, 20g of sijichun, 20g of mint and 20g of pteris latifolia. The preparation method of the traditional Chinese medicine composition for treating hemorrhoids in the embodiment is the same as that in the embodiment 1.
Example 4
A traditional Chinese medicine composition for treating hemorrhoids comprises the following raw materials in parts by weight: 30g of rheum officinale, 30g of rhizoma paridis, 40g of momordica grosvenori, 25g of kudzuvine leaf, 25g of sijichun, 25g of mint and 25g of pteris latifolia.
The preparation method of the traditional Chinese medicine composition for treating hemorrhoids comprises the following steps:
1. grinding the above components respectively and sieving with 80 mesh sieve to obtain medicinal powder; weighing the medicinal powders according to the proportion, and uniformly mixing for later use;
2. and (3) heating the vaseline to be completely melted, adding the mixed medicinal powder obtained in the step (1), fully and uniformly stirring, and cooling to obtain the ointment.
Example 5
A traditional Chinese medicine composition for treating hemorrhoids comprises the following raw materials in parts by weight: 35g of rheum officinale, 35g of rhizoma paridis, 35g of momordica grosvenori, 18g of kudzuvine leaf, 30g of sijichun, 18g of mint and 18g of pteris latifolia.
The preparation method of the traditional Chinese medicine composition for treating hemorrhoids comprises the following steps:
1. grinding the above components respectively and sieving with 80 mesh sieve to obtain medicinal powder; weighing the medicinal powders according to the proportion, and uniformly mixing for later use;
2. mixing the above mixed powder with pharmaceutically acceptable carrier according to conventional method in the art, and making into suppository.
In order to verify the efficacy of the present invention, the Chinese medicinal composition prepared in example 3 above was used in clinical treatment.
a. The treatment subjects were: 150 patients were randomized for treatment, 75 males and 75 females.
b. The curative effect standard is as follows:
the effect is shown: the pain and pruritus symptoms of the anus of the patient disappear, and the reduction degree of the perianal swelling is more than or equal to 2/3;
the method has the following advantages: the anus pain and pruritus symptoms of the patient are improved, and the reduction degree of perianal swelling is 1/3-2/3;
and (4) invalidation: the symptoms of anus pain and pruritus of the patient are not obviously improved, and perianal swelling is not obviously reduced.
c. The treatment method comprises the following steps:
treatment groups: after cleaning anus, the paste medicine prepared in example 3 is evenly applied to affected parts, and fixed by gauze once a day, 7 days is a treatment course, and patients do not eat spicy food and are prohibited from smoking and drinking during the application period.
d. Therapeutic results
The therapeutic effect after one treatment period is shown in table 1:
TABLE 1 clinical therapeutic Effect
Figure BDA0002515471590000041
As can be seen from table 1, the total effective rates of the male group and the female group after 7 days of treatment are 98% and 96%, respectively, which indicates that the composition of the present invention has the advantage of rapid onset of action, thereby being capable of shortening the treatment period.
Typical cases are as follows:
1. mr. populus, age 41, clinical symptoms: cough, fatigue, hemorrhoid warts are separated from anus during loading, the hemorrhoid warts need to be pushed back to reset by hand assistance, bleeding is accompanied, third-level internal hemorrhoids are diagnosed in a hospital in 2015, and the hemorrhoids recur after operation.
2. Mr. prune, age 35, clinical symptoms: the hemorrhoid-treating ointment repeatedly causes hematochezia, blood dripping and paper bleeding during wiping, the bleeding after the defecation stops automatically, the perianal pruritus and no hemorrhoid is threatened to drop, the first-class internal hemorrhoid is diagnosed, the hemorrhoid-treating ointment is used for treating the hemorrhoid-treating ointment once a day, and the hemorrhoid-treating ointment is healed for seven days without relapse and complications.
It should be noted that, for those skilled in the art, various changes and modifications can be made without departing from the inventive concept of the present invention, and these changes and modifications belong to the protection scope of the present invention.

Claims (6)

1. The traditional Chinese medicine composition for treating hemorrhoids is characterized by comprising the following raw materials in parts by weight:
15-40 parts of rheum officinale, 15-40 parts of rhizoma paridis, 15-40 parts of momordica grosvenori, 15-30 parts of kudzuvine leaf, 15-30 parts of sijichun, 15-30 parts of mint and 15-30 parts of pteris latifolia.
2. The traditional Chinese medicine composition for treating hemorrhoids as claimed in claim 1, which is characterized by comprising the following raw materials in parts by weight:
20-30 parts of rheum officinale, 20-30 parts of rhizoma paridis, 20-30 parts of momordica grosvenori, 18-20 parts of kudzuvine leaf, 18-20 parts of sijichun, 18-20 parts of mint and 18-20 parts of pteridium aquilinum.
3. A method for preparing a Chinese medicinal composition for the treatment of hemorrhoids as claimed in claim 1 or 2, comprising the steps of: grinding and sieving the raw materials respectively to obtain medicinal powder, and mixing the medicinal powder according to the raw material proportion to obtain the traditional Chinese medicine composition.
4. The method for preparing a Chinese medicinal composition for treating hemorrhoids as claimed in claim 3, wherein the raw materials are ground and sieved with a 60-80 mesh sieve.
5. Use of a Chinese medicinal composition for the treatment of hemorrhoids as defined in claim 1 or 2 in the preparation of a medicament for the treatment of hemorrhoids.
6. The use of claim 5, wherein the medicament for the treatment of hemorrhoids is an external preparation, and the external preparation is a paste, a suppository or a spray.
CN202010474728.3A 2020-05-29 2020-05-29 Traditional Chinese medicine composition for treating haemorrhoids and preparation method and application thereof Pending CN111514225A (en)

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Application Number Priority Date Filing Date Title
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