CN111494259A - Herbal antibacterial disinfectant - Google Patents
Herbal antibacterial disinfectant Download PDFInfo
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- CN111494259A CN111494259A CN202010326330.5A CN202010326330A CN111494259A CN 111494259 A CN111494259 A CN 111494259A CN 202010326330 A CN202010326330 A CN 202010326330A CN 111494259 A CN111494259 A CN 111494259A
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- 239000000645 desinfectant Substances 0.000 title claims abstract description 66
- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 42
- 239000003814 drug Substances 0.000 claims abstract description 70
- 230000003385 bacteriostatic effect Effects 0.000 claims abstract description 45
- 229920000053 polysorbate 80 Polymers 0.000 claims abstract description 45
- 239000000839 emulsion Substances 0.000 claims abstract description 36
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 29
- 244000246386 Mentha pulegium Species 0.000 claims abstract description 26
- 235000016257 Mentha pulegium Nutrition 0.000 claims abstract description 26
- 235000004357 Mentha x piperita Nutrition 0.000 claims abstract description 26
- 235000001050 hortel pimenta Nutrition 0.000 claims abstract description 26
- 241000245665 Taraxacum Species 0.000 claims abstract description 25
- 235000005187 Taraxacum officinale ssp. officinale Nutrition 0.000 claims abstract description 25
- 241000246044 Sophora flavescens Species 0.000 claims abstract description 17
- 238000002360 preparation method Methods 0.000 claims abstract description 14
- 239000007788 liquid Substances 0.000 claims description 73
- 238000001914 filtration Methods 0.000 claims description 44
- 238000002156 mixing Methods 0.000 claims description 19
- 238000002386 leaching Methods 0.000 claims description 17
- 239000001525 mentha piperita l. herb oil Substances 0.000 claims description 12
- 235000019477 peppermint oil Nutrition 0.000 claims description 12
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 claims description 11
- 239000000463 material Substances 0.000 claims description 10
- 238000000034 method Methods 0.000 claims 3
- 238000004659 sterilization and disinfection Methods 0.000 abstract description 8
- 230000000694 effects Effects 0.000 abstract description 5
- 201000010099 disease Diseases 0.000 abstract description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 4
- 241000411851 herbal medicine Species 0.000 abstract description 3
- 229940079593 drug Drugs 0.000 abstract description 2
- 208000015181 infectious disease Diseases 0.000 abstract description 2
- 230000000472 traumatic effect Effects 0.000 abstract description 2
- 239000000284 extract Substances 0.000 description 27
- 230000000052 comparative effect Effects 0.000 description 9
- 240000005001 Paeonia suffruticosa Species 0.000 description 4
- 235000003889 Paeonia suffruticosa Nutrition 0.000 description 4
- 241000588724 Escherichia coli Species 0.000 description 3
- 241000191967 Staphylococcus aureus Species 0.000 description 3
- 238000005406 washing Methods 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 2
- 241000222122 Candida albicans Species 0.000 description 2
- 229940095731 candida albicans Drugs 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 229940067866 dandelion extract Drugs 0.000 description 2
- 235000020691 dandelion extract Nutrition 0.000 description 2
- 229920000136 polysorbate Polymers 0.000 description 2
- 239000001845 taraxacum officinale leaf extract Substances 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- OSDLLIBGSJNGJE-UHFFFAOYSA-N 4-chloro-3,5-dimethylphenol Chemical class CC1=CC(O)=CC(C)=C1Cl OSDLLIBGSJNGJE-UHFFFAOYSA-N 0.000 description 1
- 208000006877 Insect Bites and Stings Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 229960003333 chlorhexidine gluconate Drugs 0.000 description 1
- YZIYKJHYYHPJIB-UUPCJSQJSA-N chlorhexidine gluconate Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.C1=CC(Cl)=CC=C1NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NC1=CC=C(Cl)C=C1 YZIYKJHYYHPJIB-UUPCJSQJSA-N 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
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- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
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- A—HUMAN NECESSITIES
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- A61Q19/10—Washing or bathing preparations
Abstract
The invention discloses a herbal antibacterial disinfectant, and belongs to the technical field of traditional Chinese medicine disinfection. The invention consists of the following components: radix Sophorae Flavescentis extractive solution, cortex moutan extractive solution, herba Taraxaci extractive solution, and oleum Menthae Dementholatum-Tween 80 emulsion; wherein the weight of the peppermint oil-tween 80 emulsion is 0.2-0.5 percent of the weight of the herbal bacteriostatic disinfectant; the sophora flavescens extracting solution, the moutan bark extracting solution and the dandelion extracting solution are respectively 1-5 parts by weight of sophora flavescens water extracting solution, 3-9 parts by weight of moutan bark water extracting solution and 10-30 parts by weight of dandelion water extracting solution. The Chinese herbal medicine bacteriostatic disinfectant disclosed by the invention is a pure Chinese medicinal preparation, has a good bacteriostatic and antibacterial effect, is small in dosage, convenient to use and wide in application range, can be used for curing traumatic infection and the like, is safe and reliable, does not relapse after curing, does not rely on drug properties, does not have side effects, and can achieve the effect of treating both principal and secondary aspects of diseases.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicine disinfection, and particularly relates to a herbal antibacterial disinfectant.
Background
The bacteria are very small and exist everywhere, however, some bacteria are pathogens of diseases, can spread the diseases among normal human bodies through various ways, such as contact, alimentary canal, respiratory tract, insect bite and the like, have strong infectivity and great harm to the society. Therefore, people develop and manufacture various bacteriostatic products for daily hand washing, clothes disinfection, wound disinfection and the like.
At present, a plurality of bacteriostatic and disinfectant products for washing hands in the market comprise Chinese herbal medicine hand sanitizer, chlorhexidine gluconate antibacterial hand sanitizer, PCMX series bacteriostatic hand sanitizer and the like.
The existing hand washing antibacterial and disinfection products basically have better antibacterial effect, but scientific research has no limit, and how to further improve the antibacterial effect of the antibacterial and disinfection products is still a technical difficulty to be overcome by the antibacterial and disinfection products.
The traditional Chinese medicine hand sanitizer is popular with consumers in recent years, is suitable for people of any age group, and has no damage to skin.
Therefore, the development of the herbal bacteriostatic disinfectant with good bacteriostatic effect has important practical significance.
Disclosure of Invention
In order to make up the defects of the prior art, the invention provides a herbal bacteriostatic disinfectant.
The technical scheme of the invention is as follows:
a herbal bacteriostatic disinfectant consists of the following components: radix Sophorae Flavescentis extractive solution, cortex moutan extractive solution, herba Taraxaci extractive solution, and oleum Menthae Dementholatum-Tween 80 emulsion; wherein the weight of the peppermint oil-tween 80 emulsion is 0.2-0.5 percent of the weight of the herbal bacteriostatic disinfectant; the sophora flavescens extracting solution, the moutan bark extracting solution and the dandelion extracting solution are respectively 1-5 parts by weight of sophora flavescens water extracting solution, 3-9 parts by weight of moutan bark water extracting solution and 10-30 parts by weight of dandelion water extracting solution.
Preferably, in the peppermint oil-tween 80 emulsion, the mass ratio of the peppermint oil to the tween 80 is 8-12: 1.
Furthermore, in the peppermint oil-tween 80 emulsion, the mass ratio of the peppermint oil to the tween 80 is 10: 1.
Preferably, the weight ratio of the radix sophorae flavescentis to the cortex moutan to the dandelion is 2-4: 5-8: 15-25.
The preparation method of the herbal bacteriostatic disinfectant comprises the following steps:
1) decocting radix Sophorae Flavescentis, cortex moutan and herba Taraxaci in water, leaching, filtering to obtain first medicinal liquid, and keeping the residue;
2) adding water into the dregs, decocting, leaching and filtering to obtain a second liquid medicine;
3) mixing the first liquid medicine and the second liquid medicine, and filtering to obtain a mixed extracting solution;
4) concentrating the mixed extractive solution to obtain radix Sophorae Flavescentis extractive solution, cortex moutan extractive solution, and herba Taraxaci extractive solution;
5) adding the peppermint oil-tween 80 emulsion into the concentrated solution of the sophora flavescens extracting solution, the moutan bark extracting solution and the dandelion extracting solution, and uniformly mixing to obtain the herbal antibacterial disinfectant.
Preferably, in the step 1), the ratio of the liquid medicine to the liquid medicine is 1: 5-7, and the leaching time is 0.6-1.5 h.
Preferably, in the step 2), the ratio of the liquid medicine to the liquid medicine is 1: 3-5, and the leaching time is 0.6-1.5 h.
Preferably, in the step 3), the filtering is performed by filtering the mixture for a plurality of times through 200-300-mesh gauze, and then performing fine filtering through a 0.45-micron filter.
Preferably, in the step 4), the mixed extracting solution is concentrated to 3-4 times of the weight of the medicinal materials.
The invention has the beneficial effects that:
1. the antibacterial disinfectant is prepared by compounding radix sophorae flavescentis extract, cortex moutan extract, dandelion extract and peppermint oil according to a certain proportion, and the antibacterial rate of the antibacterial disinfectant on staphylococcus aureus, escherichia coli and the like is as high as 100%;
2. the Chinese herbal medicine bacteriostatic disinfectant disclosed by the invention is a pure Chinese medicinal preparation, has a good bacteriostatic and antibacterial effect, is small in dosage, convenient to use and wide in application range, can be used for curing traumatic infection and the like, is safe and reliable, does not relapse after curing, does not rely on drug properties, does not have side effects, and can achieve the effect of treating both principal and secondary aspects of diseases.
Detailed Description
First, preparation example
Example 1:
a herbal antibacterial disinfectant comprises radix Sophorae Flavescentis extract, cortex moutan extract, herba Taraxaci extract, and oleum Menthae Dementholatum-Tween 80 emulsion; in the peppermint oil-tween 80 emulsion, the mass ratio of the peppermint oil to the tween 80 is 10: 1.
The preparation method of the herbal bacteriostatic disinfectant comprises the following steps:
1) adding water into 4 parts of radix sophorae flavescentis, 7 parts of cortex moutan and 20 parts of dandelion in a liquid medicine ratio of 1:6, decocting and extracting for 1 hour, filtering to obtain a liquid medicine I, and reserving dregs for later use;
2) adding water into the medicine residues, decocting and leaching for 1 h at a medicine liquid ratio of 1:4, and filtering to obtain a medicine liquid II;
3) mixing the first liquid medicine and the second liquid medicine, filtering the mixed liquid for 4 times by 200-mesh gauze, and then finely filtering by a 0.45-micron filter to obtain a mixed extracting solution;
4) concentrating the mixed extractive solution to 3 times of the medicinal materials to obtain concentrated solutions of radix Sophorae Flavescentis extractive solution, cortex moutan extractive solution, and herba Taraxaci extractive solution;
5) adding the peppermint oil-Tween 80 emulsion into the concentrated solution of the sophora flavescens extracting solution, the moutan bark extracting solution and the dandelion extracting solution, and uniformly mixing (the weight is 0.3 percent of the weight of the herbal antibacterial disinfectant) to obtain the herbal antibacterial disinfectant.
Example 2:
a herbal antibacterial disinfectant comprises radix Sophorae Flavescentis extract, cortex moutan extract, herba Taraxaci extract, and oleum Menthae Dementholatum-Tween 80 emulsion; in the peppermint oil-tween 80 emulsion, the mass ratio of the peppermint oil to the tween 80 is 12: 1.
The preparation method of the herbal bacteriostatic disinfectant comprises the following steps:
1) adding water into 5 parts of radix sophorae flavescentis, 3 parts of tree peony bark and 10 parts of dandelion in a liquid medicine ratio of 1:5, decocting and extracting for 1.5 hours, filtering to obtain a liquid medicine I, and reserving dregs for later use;
2) adding water into the residue at a ratio of 1:3, decocting and leaching for 1.5 h, and filtering to obtain a second liquid medicine;
3) mixing the first liquid medicine and the second liquid medicine, filtering the mixed liquid for 3 times by 300-mesh gauze, and then finely filtering by a 0.45-micron filter to obtain a mixed extracting solution;
4) concentrating the mixed extractive solution to 3 times of the medicinal materials to obtain concentrated solutions of radix Sophorae Flavescentis extractive solution, cortex moutan extractive solution, and herba Taraxaci extractive solution;
5) adding the peppermint oil-Tween 80 emulsion into the concentrated solution of the sophora flavescens extracting solution, the moutan bark extracting solution and the dandelion extracting solution, and uniformly mixing (the weight is 0.5 percent of the weight of the herbal antibacterial disinfectant) to obtain the herbal antibacterial disinfectant.
Example 3:
a herbal antibacterial disinfectant comprises radix Sophorae Flavescentis extract, cortex moutan extract, herba Taraxaci extract, and oleum Menthae Dementholatum-Tween 80 emulsion; in the peppermint oil-tween 80 emulsion, the mass ratio of the peppermint oil to the tween 80 is 8: 1.
The preparation method of the herbal bacteriostatic disinfectant comprises the following steps:
1) adding water into 1 part of radix sophorae flavescentis, 9 parts of cortex moutan and 30 parts of dandelion in a liquid medicine ratio of 1:7, decocting and extracting for 0.8 h, filtering to obtain a liquid medicine I, and reserving dregs for later use;
2) adding water into the residue at a ratio of 1:5, decocting and leaching for 1.5 h, and filtering to obtain a second liquid medicine;
3) mixing the first liquid medicine and the second liquid medicine, filtering the mixed liquid for 3 times by 200-mesh gauze, and then finely filtering by a 0.45-micron filter to obtain a mixed extracting solution;
4) concentrating the mixed extractive solution to 4 times of the medicinal materials to obtain concentrated solutions of radix Sophorae Flavescentis extractive solution, cortex moutan extractive solution, and herba Taraxaci extractive solution;
5) adding the peppermint oil-Tween 80 emulsion into the concentrated solution of the sophora flavescens extracting solution, the moutan bark extracting solution and the dandelion extracting solution, and uniformly mixing (the weight is 0.2 percent of the weight of the herbal antibacterial disinfectant) to obtain the herbal antibacterial disinfectant.
Example 4:
a herbal antibacterial disinfectant comprises radix Sophorae Flavescentis extract, cortex moutan extract, herba Taraxaci extract, and oleum Menthae Dementholatum-Tween 80 emulsion; in the peppermint oil-tween 80 emulsion, the mass ratio of the peppermint oil to the tween 80 is 10: 1.
The preparation method of the herbal bacteriostatic disinfectant comprises the following steps:
1) adding water into 3 parts of radix sophorae flavescentis, 6 parts of tree peony bark and 20 parts of dandelion in a liquid medicine ratio of 1:5, decocting and extracting for 1 hour, filtering to obtain a liquid medicine I, and reserving dregs for later use;
2) adding water into the medicine residues, decocting and leaching for 1 h at a medicine liquid ratio of 1:4, and filtering to obtain a medicine liquid II;
3) mixing the first liquid medicine and the second liquid medicine, filtering the mixed liquid for 3 times by 200-mesh gauze, and then finely filtering by a 0.45-micron filter to obtain a mixed extracting solution;
4) concentrating the mixed extractive solution to 3 times of the medicinal materials to obtain concentrated solutions of radix Sophorae Flavescentis extractive solution, cortex moutan extractive solution, and herba Taraxaci extractive solution;
5) adding the peppermint oil-Tween 80 emulsion into the concentrated solution of the sophora flavescens extracting solution, the moutan bark extracting solution and the dandelion extracting solution, and uniformly mixing (the weight is 0.4 percent of the weight of the herbal antibacterial disinfectant) to obtain the herbal antibacterial disinfectant.
Example 5:
a herbal antibacterial disinfectant comprises radix Sophorae Flavescentis extract, cortex moutan extract, herba Taraxaci extract, and oleum Menthae Dementholatum-Tween 80 emulsion; in the peppermint oil-tween 80 emulsion, the mass ratio of the peppermint oil to the tween 80 is 10: 1.
The preparation method of the herbal bacteriostatic disinfectant comprises the following steps:
1) adding water into 2 parts of radix sophorae flavescentis, 8 parts of tree peony bark and 25 parts of dandelion in a liquid medicine ratio of 1:6, decocting and extracting for 1 hour, filtering to obtain a liquid medicine I, and reserving dregs for later use;
2) adding water into the residue at a ratio of 1:3, decocting and leaching for 1.5 h, and filtering to obtain a second liquid medicine;
3) mixing the first liquid medicine and the second liquid medicine, filtering the mixed liquid for 4 times by 200-mesh gauze, and then finely filtering by a 0.45-micron filter to obtain a mixed extracting solution;
4) concentrating the mixed extractive solution to 3 times of the medicinal materials to obtain concentrated solutions of radix Sophorae Flavescentis extractive solution, cortex moutan extractive solution, and herba Taraxaci extractive solution;
5) adding the peppermint oil-Tween 80 emulsion into the concentrated solution of the sophora flavescens extracting solution, the moutan bark extracting solution and the dandelion extracting solution, and uniformly mixing (the weight is 0.3 percent of the weight of the herbal antibacterial disinfectant) to obtain the herbal antibacterial disinfectant.
Comparative example 1
A herbal antibacterial disinfectant comprises radix Sophorae Flavescentis extract, herba Taraxaci extract, and oleum Menthae Dementholatum-Tween 80 emulsion; in the peppermint oil-tween 80 emulsion, the mass ratio of the peppermint oil to the tween 80 is 10: 1.
The preparation method of the herbal bacteriostatic disinfectant comprises the following steps:
1) adding water into 4 parts of radix sophorae flavescentis and 20 parts of dandelion in a medicine liquid ratio of 1:6, decocting and extracting for 1 hour, filtering to obtain a medicine liquid I, and reserving medicine residues for later use;
2) adding water into the medicine residues, decocting and leaching for 1 h at a medicine liquid ratio of 1:4, and filtering to obtain a medicine liquid II;
3) mixing the first liquid medicine and the second liquid medicine, filtering the mixed liquid for 4 times by 200-mesh gauze, and then finely filtering by a 0.45-micron filter to obtain a mixed extracting solution;
4) concentrating the mixed extractive solution to 3 times of the medicinal materials to obtain concentrated solution of radix Sophorae Flavescentis extractive solution and herba Taraxaci extractive solution;
5) adding the peppermint oil-tween 80 emulsion into the concentrated solution of the radix sophorae flavescentis extracting solution and the dandelion extracting solution, and uniformly mixing (the weight is 0.3 percent of the weight of the herbal bacteriostatic disinfectant) to obtain the herbal bacteriostatic disinfectant.
Compared with example 1, no moutan bark extract was included.
Comparative example 2:
a herbal antibacterial disinfectant comprises radix Sophorae Flavescentis extract, cortex moutan extract, herba Taraxaci extract, and oleum Menthae Dementholatum-Tween 80 emulsion; in the peppermint oil-tween 80 emulsion, the mass ratio of the peppermint oil to the tween 80 is 10: 1.
The preparation method of the herbal bacteriostatic disinfectant comprises the following steps:
1) adding water into 7 parts of tree peony bark and 20 parts of dandelion in a liquid medicine ratio of 1:6, decocting and leaching for 1 hour, filtering to obtain a liquid medicine I, and reserving dregs for later use;
2) adding water into the medicine residues, decocting and leaching for 1 h at a medicine liquid ratio of 1:4, and filtering to obtain a medicine liquid II;
3) mixing the first liquid medicine and the second liquid medicine, filtering the mixed liquid for 4 times by 200-mesh gauze, and then finely filtering by a 0.45-micron filter to obtain a mixed extracting solution;
4) concentrating the mixed extractive solution to 3 times of the medicinal materials to obtain concentrated solution of cortex moutan extractive solution and herba Taraxaci extractive solution;
5) adding the peppermint oil-Tween 80 emulsion into the concentrated solution of the moutan bark extract and the dandelion extract, and uniformly mixing (the weight is 0.3 percent of the weight of the herbal bacteriostatic disinfectant) to obtain the herbal bacteriostatic disinfectant.
In contrast to example 1, the extract of Sophora flavescens Aiton was not included.
Comparative example 3:
a herbal antibacterial disinfectant comprises radix Sophorae Flavescentis extractive solution, cortex moutan extractive solution, and herba Taraxaci extractive solution;
the preparation method of the herbal bacteriostatic disinfectant comprises the following steps:
1) adding water into 4 parts of radix sophorae flavescentis, 7 parts of cortex moutan and 20 parts of dandelion in a liquid medicine ratio of 1:6, decocting and extracting for 1 hour, filtering to obtain a liquid medicine I, and reserving dregs for later use;
2) adding water into the medicine residues, decocting and leaching for 1 h at a medicine liquid ratio of 1:4, and filtering to obtain a medicine liquid II;
3) mixing the first liquid medicine and the second liquid medicine, filtering the mixed liquid for 4 times by 200-mesh gauze, and then finely filtering by a 0.45-micron filter to obtain a mixed extracting solution;
4) concentrating the mixed extractive solution to 3 times of the medicinal materials to obtain concentrated solutions of radix Sophorae Flavescentis extractive solution, cortex moutan extractive solution, and herba Taraxaci extractive solution; the concentrated solution is used as the bacteriostatic disinfectant of the comparative example.
In contrast to example 1, this comparative example does not include a peppermint oil-tween 80 emulsion.
II, bacteriostatic experiment:
the test is carried out according to the regulations and requirements of annex B of sanitation department 'hygienic index of disposable sanitary products' (GB 15979-2002) and sanitation department 'disinfection technical Specification' 11 month edition 2002, 2.1.1.2, the 5 th to 10 th generations are taken, the culture is cultured for 18 to 24 hours at 37 ℃, the fresh culture on the inclined plane is tested, the sample of the product is tested by an accelerated test method, the test is repeated for three times (the data in the table is an average value), and the result shows that:
the antibacterial disinfectant acts for 2min, 5min, 10min and 20min respectively, and the antibacterial rate results of the antibacterial disinfectant on escherichia coli, staphylococcus aureus and candida albicans are shown in tables 1, 2 and 3 respectively.
TABLE 1 results of bacteriostasis of antibacterial disinfectant liquid to Escherichia coli in each example and comparative example
TABLE 2 bacteriostatic results of bacteriostatic disinfectant solutions of examples and comparative examples on Staphylococcus aureus
TABLE 3 bacteriostatic results of bacteriostatic disinfectant solutions of examples and comparative examples on Candida albicans
As can be seen from tables 1, 2 and 3, the bacteriostatic effect of the bacteriostatic disinfectant of each embodiment of the invention is significantly improved compared with that of the bacteriostatic disinfectant of the comparative example. Therefore, each component of the sophora flavescens extract, the moutan bark extract and the peppermint oil-tween emulsion has a significant contribution effect on the antibacterial effect. The antibacterial disinfectant consists of the sophora flavescens extracting solution, the moutan bark extracting solution, the dandelion extracting solution and the peppermint oil-tween emulsion, has one-out of the components, is used in a compound way, and has a very good antibacterial effect.
Claims (9)
1. The herbal bacteriostatic disinfectant is characterized by comprising the following components: radix Sophorae Flavescentis extractive solution, cortex moutan extractive solution, herba Taraxaci extractive solution, and oleum Menthae Dementholatum-Tween 80 emulsion; wherein the weight of the peppermint oil-tween 80 emulsion is 0.2-0.5 percent of the weight of the herbal bacteriostatic disinfectant; the sophora flavescens extracting solution, the moutan bark extracting solution and the dandelion extracting solution are respectively 1-5 parts by weight of sophora flavescens water extracting solution, 3-9 parts by weight of moutan bark water extracting solution and 10-30 parts by weight of dandelion water extracting solution.
2. The herbal bacteriostatic disinfectant liquid as set forth in claim 1, which is characterized in that: in the peppermint oil-tween 80 emulsion, the mass ratio of the peppermint oil to the tween 80 is 8-12: 1.
3. The herbal bacteriostatic disinfectant liquid as set forth in claim 2, which is characterized in that: in the peppermint oil-tween 80 emulsion, the mass ratio of the peppermint oil to the tween 80 is 10: 1.
4. The herbal bacteriostatic disinfectant liquid as claimed in claim 1 or 2, wherein: the weight ratio of the sophora flavescens, the moutan bark and the dandelion is 2-4: 5-8: 15-25.
5. The preparation method of the herbal bacteriostatic disinfectant as claimed in claim 1, which comprises the following steps: 1) decocting radix Sophorae Flavescentis, cortex moutan and herba Taraxaci in water, leaching, filtering to obtain first medicinal liquid, and keeping the residue; 2) adding water into the dregs, decocting, leaching and filtering to obtain a second liquid medicine; 3) mixing the first liquid medicine and the second liquid medicine, and filtering to obtain a mixed extracting solution; 4) concentrating the mixed extractive solution to obtain radix Sophorae Flavescentis extractive solution, cortex moutan extractive solution, and herba Taraxaci extractive solution; 5) adding the peppermint oil-tween 80 emulsion into the concentrated solution of the sophora flavescens extracting solution, the moutan bark extracting solution and the dandelion extracting solution, and uniformly mixing to obtain the herbal antibacterial disinfectant.
6. The preparation method of the herbal bacteriostatic disinfectant as claimed in claim 5, which is characterized in that: in the step 1), the ratio of the liquid medicine to the liquid medicine is 1: 5-7, and the leaching time is 0.6-1.5 h.
7. The method for preparing the herbal bacteriostatic disinfectant as claimed in claim 5 or 6, which is characterized in that: in the step 2), the ratio of the liquid medicine to the liquid medicine is 1: 3-5, and the leaching time is 0.6-1.5 h.
8. The method for preparing the herbal bacteriostatic disinfectant as claimed in claim 5 or 6, which is characterized in that: in the step 3), the filtration is carried out by filtering for a plurality of times through 200-300 meshes of gauze and then carrying out fine filtration through a 0.45-micron filter.
9. The method for preparing the herbal bacteriostatic disinfectant as claimed in claim 5 or 6, which is characterized in that: in the step 4), the mixed extracting solution is concentrated to 3-4 times of the weight of the medicinal materials.
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