CN111481624A - Preparation method of nine-process rhizoma polygonati granules - Google Patents
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Abstract
The invention provides a preparation method of a nine-process rhizoma polygonati granule, which comprises the following steps: s1: drying the steamed rhizoma Polygonati in sunlight room, and steaming and drying for nine times to obtain nine times; s2: crushing the nine-process sealwort in the step S1 by using ultrasonic crushing equipment to obtain sealwort powder, and filtering the sealwort powder by using a filtering device for later use; s3: the sealwort powder, the mannitol and the mulberry leaf powder in the S2 are respectively added into a dissolving tank according to the proportion of 10-12:4-6:2-3, then ionized water with the weight 30-36 times of the sealwort powder is added into the dissolving tank, and the dissolving tank is stirred for 40-50min by using a stirring device inside the dissolving tank to obtain a solution A. The nine-process rhizoma polygonati granules prepared by the invention have low production cost and stronger water absorption resistance.
Description
Technical Field
The invention relates to the technical field of preparation of rhizoma polygonati granules, in particular to a preparation method of nine-process rhizoma polygonati granules.
Background
Rhizoma Polygonati is dried rhizome of Polygonatum kingianum, Polygonatum sibiricum or Polygonatum cyrtonema of Liliaceae. According to different shapes, it is called "rheum officinale essence", "polygonatum kingianum" and "polygonatum zingiberense". The sealwort is a traditional Chinese medicine in China, belongs to medicinal and edible homologous Chinese herbal medicines, is sweet in taste and neutral in nature, and has the effects of tonifying qi and yin, strengthening spleen, moistening lung and tonifying kidney. The rhizoma Polygonati polysaccharide is a plant polysaccharide extracted from rhizome of rhizoma Polygonati, and has various biological activities and complex structure. The composition of polysaccharides in different species of polygonatum exists differently, wherein the composition of polysaccharides contained in 3 species of polygonatum cyrtonema, polygonatum and polygonatum kingianum exists obviously differently, and the composition of polygonatum polysaccharides also exists differently from other polysaccharides. It is reported that polygonatum contains active ingredients such as polysaccharide, saponin, anthraquinone compounds, alkaloid, cardiac glycoside, vitamins and the like, and can delay senility, enhance the immune function, reduce blood sugar, reduce blood fat, resist inflammation, bacteria, viruses, tumors and the like. The polygonatum processed by the traditional process has the problem of easy water absorption, so the preparation method of the nine-process polygonatum granules is provided.
Disclosure of Invention
The invention provides a preparation method of a nine-process polygonatum sibiricum granule, which solves the problem that polygonatum sibiricum processed by the traditional process is easy to absorb water.
In order to achieve the purpose, the invention adopts the following technical scheme:
a preparation method of nine-process rhizoma polygonati granules comprises the following steps:
s1: drying the steamed rhizoma Polygonati in sunlight room, and steaming and drying for nine times to obtain nine times;
s2: crushing the nine-process sealwort in the step S1 by using ultrasonic crushing equipment to obtain sealwort powder, and filtering the sealwort powder by using a filtering device for later use;
s3: respectively adding the polygonatum sibiricum powder, the mannitol and the mulberry leaf powder in the S2 into a dissolving tank according to the proportion of 10-12:4-6:2-3, then adding 30-36 times of ionized water by weight of the polygonatum sibiricum powder into the dissolving tank, and stirring the dissolving tank by using a stirring device in the dissolving tank for 40-50min to obtain a solution A;
s4, adding α -amylase into the solution A in the S3 to carry out activation treatment for 60-80min to obtain a solution B;
s5: adding the solution B in the S4 and 5 wt% -10 wt% of maltodextrin supernatant into a mixing tank according to the ratio of 2-3:1, stirring the mixed solution in the mixing tank at a high speed by using a stirring device in the mixing tank, and adding 4-6g of calcium oxide into each liter of mixed solution in the stirring process until the water content of the mixed solution reaches 10-12%;
s6: crystallizing the mixed solution with the water content of 10-12% in the S5 by using a crystallization tower to obtain mixed crystals;
s7: drying the mixed crystal in the S6 by using drying equipment, and then crushing by using an ultrasonic crusher to obtain mixed powder;
s8: and (S7) granulating the mixed powder by using a granulator, and then coating by using a coating machine to obtain the nine-process rhizoma polygonati granules.
Preferably, in S1, the steaming time is: 8-10 hours for the 1 st time, 6-8 hours for the 2 nd time, 4-6 hours for the 3 rd time, 2-4 hours for the 4 th time, 2-3 hours for the 5 th time, 1-2 hours for the 6 th time, 1-1.5 hours for the 7 th time, 0.5-1 hour for the 8 th time, and 20-40 minutes for the 9 th time; the air-drying degree is seven to nine times dry.
Preferably, in S2, the filtering device is a filter mesh cloth with 16-18 meshes.
Preferably, in S3, the water temperature inside the dissolving tank is set to be 35-45 ℃, and 5-10ml of cosolvent is added into the dissolving tank every 5min during the stirring operation.
Preferably, in S4, the temperature of the activation treatment is set to 40 to 50 ℃.
Preferably, in the S5, the internal temperature of the mixing tank is set to 40 to 50 ℃.
Preferably, in the S6, the temperature inside the crystallization tower is set to be 110-120 ℃.
Preferably, in S7, the drying device performs the drying operation by using a microwave technique.
Compared with the prior art, the nine-process rhizoma polygonati granules prepared by the invention have low production cost and stronger water absorption resistance.
Detailed Description
The technical solutions in the embodiments of the present invention are clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments.
Example one
The embodiment provides a preparation method of a nine-process rhizoma polygonati granule, which comprises the following steps:
s1: placing the steamed sealwort each time in a sunlight room for airing, and repeatedly steaming and airing for nine times to obtain nine times of steamed sealwort, wherein the steaming time is as follows: 10 hours at 1, 8 hours at 2, 6 hours at 3, 4 hours at 4, 3 hours at 5, 2 hours at 6, 1 hour at 7, 1 hour at 8, and 40 minutes at 9; the airing degree is seven-dry;
s2: crushing the nine-process sealwort in the S1 by using ultrasonic crushing equipment to obtain sealwort powder, and filtering the sealwort powder by using a 16-18-mesh filter screen cloth for later use;
s3: respectively adding the polygonatum sibiricum powder, the mannitol and the mulberry leaf powder in the S2 into a dissolving tank according to the proportion of 10:6:2, then adding 30 times of ionized water by weight of the polygonatum sibiricum powder into the dissolving tank, and stirring the dissolving tank for 40min by using a stirring device in the dissolving tank, wherein the water temperature in the dissolving tank is set to be 35 ℃, and 5ml of cosolvent is added into the dissolving tank every 5min in the stirring operation process to obtain a solution A;
s4, adding α -amylase into the solution A in the S3 to perform activation treatment for 60min, wherein the temperature of the activation treatment is set to be 40 ℃, and obtaining a solution B;
s5: adding the solution B and 5 wt% of maltodextrin supernatant in the S4 into a mixing tank according to the ratio of 2:1, setting the internal temperature of the mixing tank to be 40 ℃, stirring the mixed solution in the mixing tank at a high speed by using a stirring device in the mixing tank, and adding 4g of calcium oxide into each liter of mixed solution in the stirring process until the water content of the mixed solution reaches 10%;
s6: crystallizing the mixed solution with the water content of 10% in the S5 by using a crystallization tower, wherein the temperature inside the crystallization tower is set to be 110 ℃, and obtaining mixed crystals;
s7: drying the mixed crystal in the S6 by using drying equipment, wherein the drying equipment performs drying operation by using a microwave technology, and then crushing by using an ultrasonic crusher to obtain mixed powder;
s8: and (S7) granulating the mixed powder by using a granulator, and then coating by using a coating machine to obtain the nine-process rhizoma polygonati granules.
Example two
The embodiment provides a preparation method of a nine-process rhizoma polygonati granule, which comprises the following steps:
s1: placing the steamed sealwort each time in a sunlight room for airing, and repeatedly steaming and airing for nine times to obtain nine times of steamed sealwort, wherein the steaming time is as follows: 8 hours for 1, 6 hours for 2, 4 hours for 3, 2 hours for 4, 2 hours for 5, 2 hours for 6, 1 hour for 7, 1 hour for 8, 0.5 hour for 8, 30 minutes for 9; drying in the air to the extent of eighty percent dryness;
s2: crushing the nine-process sealwort in the S1 by using ultrasonic crushing equipment to obtain sealwort powder, and filtering the sealwort powder by using a 16-18-mesh filter screen cloth for later use;
s3: adding rhizoma polygonati powder, mannitol and mulberry leaf powder in S2 into a dissolving tank respectively according to the ratio of 11:5:2.5, then adding ionized water 33 times of the weight of the rhizoma polygonati powder into the dissolving tank, and stirring the dissolving tank for 45min by using a stirring device in the dissolving tank, wherein the water temperature in the dissolving tank is set to be 40 ℃, and 7.5ml of cosolvent is added into the dissolving tank every 5min during the stirring operation to obtain a solution A;
s4, adding α -amylase into the solution A in the S3 to perform activation treatment for 70min, wherein the temperature of the activation treatment is set to be 45 ℃, and obtaining a solution B;
s5: adding the solution B and 7.5 wt% of maltodextrin supernatant in the S4 into a mixing tank according to the ratio of 2.5:1, setting the internal temperature of the mixing tank to be 45 ℃, stirring the mixed solution in the mixing tank at a high speed by using a stirring device in the mixing tank, and adding 6g of calcium oxide into each liter of mixed solution in the stirring process until the water content of the mixed solution reaches 11%;
s6: crystallizing the mixed solution with the water content of 11% in the S5 by using a crystallization tower, wherein the temperature inside the crystallization tower is set to be 115 ℃, and obtaining mixed crystals;
s7: drying the mixed crystal in the S6 by using drying equipment, wherein the drying equipment performs drying operation by using a microwave technology, and then crushing by using an ultrasonic crusher to obtain mixed powder;
s8: and (S7) granulating the mixed powder by using a granulator, and then coating by using a coating machine to obtain the nine-process rhizoma polygonati granules.
EXAMPLE III
The embodiment provides a preparation method of a nine-process rhizoma polygonati granule, which comprises the following steps:
s1: placing the steamed sealwort each time in a sunlight room for airing, and repeatedly steaming and airing for nine times to obtain nine times of steamed sealwort, wherein the steaming time is as follows: 8 hours for 1, 6 hours for 2, 4 hours for 3, 2 hours for 4, 2.5 hours for 5, 1.5 hours for 6, 1 hour for 7, 1 hour for 8, and 20 minutes for 9; the airing degree is nine times dry;
s2: crushing the nine-process sealwort in the S1 by using ultrasonic crushing equipment to obtain sealwort powder, and filtering the sealwort powder by using a 16-18-mesh filter screen cloth for later use;
s3: respectively adding rhizoma polygonati powder, mannitol and mulberry leaf powder in S2 into a dissolving tank according to the proportion of 12:4:3, then adding ionized water 36 times the weight of the rhizoma polygonati powder into the dissolving tank, and stirring the dissolving tank for 50min by using a stirring device in the dissolving tank, wherein the water temperature in the dissolving tank is set to be 45 ℃, and 10ml of cosolvent is added into the dissolving tank every 5min during the stirring operation to obtain a solution A;
s4, adding α -amylase into the solution A in the S3 to perform activation treatment for 80min, wherein the temperature of the activation treatment is set to be 50 ℃, and obtaining a solution B;
s5: adding the solution B and 10 wt% of maltodextrin supernatant in the S4 into a mixing tank according to the ratio of 3:1, setting the internal temperature of the mixing tank to be 50 ℃, stirring the mixed solution in the mixing tank at a high speed by using a stirring device in the mixing tank, and adding 6g of calcium oxide into each liter of mixed solution in the stirring process until the water content of the mixed solution reaches 12%;
s6: crystallizing the mixed solution with the water content of 12% in the S5 by using a crystallization tower, wherein the temperature inside the crystallization tower is set to be 120 ℃, and obtaining mixed crystals;
s7: drying the mixed crystal in the S6 by using drying equipment, wherein the drying equipment performs drying operation by using a microwave technology, and then crushing by using an ultrasonic crusher to obtain mixed powder;
s8: and (S7) granulating the mixed powder by using a granulator, and then coating by using a coating machine to obtain the nine-process rhizoma polygonati granules.
Through the three embodiments, the nine-process polygonatum sibiricum granules prepared by the invention have low production cost and stronger water absorption resistance, wherein the second embodiment is the best embodiment.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.
Claims (8)
1. A preparation method of nine-process rhizoma polygonati granules is characterized by comprising the following steps:
s1: drying the steamed rhizoma Polygonati in sunlight room, and steaming and drying for nine times to obtain nine times;
s2: crushing the nine-process sealwort in the step S1 by using ultrasonic crushing equipment to obtain sealwort powder, and filtering the sealwort powder by using a filtering device for later use;
s3: respectively adding the polygonatum sibiricum powder, the mannitol and the mulberry leaf powder in the S2 into a dissolving tank according to the proportion of 10-12:4-6:2-3, then adding 30-36 times of ionized water by weight of the polygonatum sibiricum powder into the dissolving tank, and stirring the dissolving tank by using a stirring device in the dissolving tank for 40-50min to obtain a solution A;
s4, adding α -amylase into the solution A in the S3 to carry out activation treatment for 60-80min to obtain a solution B;
s5: adding the solution B in the S4 and 5 wt% -10 wt% of maltodextrin supernatant into a mixing tank according to the ratio of 2-3:1, stirring the mixed solution in the mixing tank at a high speed by using a stirring device in the mixing tank, and adding 4-6g of calcium oxide into each liter of mixed solution in the stirring process until the water content of the mixed solution reaches 10-12%;
s6: crystallizing the mixed solution with the water content of 10-12% in the S5 by using a crystallization tower to obtain mixed crystals;
s7: drying the mixed crystal in the S6 by using drying equipment, and then crushing by using an ultrasonic crusher to obtain mixed powder;
s8: and (S7) granulating the mixed powder by using a granulator, and then coating by using a coating machine to obtain the nine-process rhizoma polygonati granules.
2. The method for preparing the nine-process polygonatum sibiricum granules according to claim 1, wherein in the step S1, the steaming time is as follows: 8-10 hours for the 1 st time, 6-8 hours for the 2 nd time, 4-6 hours for the 3 rd time, 2-4 hours for the 4 th time, 2-3 hours for the 5 th time, 1-2 hours for the 6 th time, 1-1.5 hours for the 7 th time, 0.5-1 hour for the 8 th time, and 20-40 minutes for the 9 th time; the airing degree is seven to nine times dry.
3. The method for preparing the nine-process polygonatum granules according to claim 1, wherein in the step S2, the filtering device is a 16-18 mesh filtering mesh cloth.
4. The method of claim 1, wherein in step S3, the temperature of the water inside the dissolving tank is set at 35-45 ℃, and 5-10ml of cosolvent is added to the dissolving tank every 5min during the stirring operation.
5. The method for preparing the nine-process polygonatum granules according to claim 1, wherein the temperature of the activation treatment in S4 is set to 40-50 ℃.
6. The method for preparing the nine-process polygonatum granules according to claim 1, wherein in the step S5, the internal temperature of the mixing tank is set to 40-50 ℃.
7. The method as claimed in claim 1, wherein the temperature inside the crystallization tower in S6 is set at 110-120 ℃.
8. The method for preparing the nine-process polygonatum granules according to claim 1, wherein in S7, the drying device performs the drying operation by using a microwave technique.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112841648A (en) * | 2021-01-20 | 2021-05-28 | 云南省农业科学院农产品加工研究所 | Preparation method and application of rhizoma polygonati |
| CN113599453A (en) * | 2021-06-04 | 2021-11-05 | 福建天人药业股份有限公司 | Processing method of polygonatum sibiricum through nine-steaming and nine-sun-drying |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102551057A (en) * | 2012-01-16 | 2012-07-11 | 周成灿 | Manyflower solomonseal rhizome food and preparation method thereof |
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- 2020-04-11 CN CN202010282145.0A patent/CN111481624A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102551057A (en) * | 2012-01-16 | 2012-07-11 | 周成灿 | Manyflower solomonseal rhizome food and preparation method thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112841648A (en) * | 2021-01-20 | 2021-05-28 | 云南省农业科学院农产品加工研究所 | Preparation method and application of rhizoma polygonati |
| CN113599453A (en) * | 2021-06-04 | 2021-11-05 | 福建天人药业股份有限公司 | Processing method of polygonatum sibiricum through nine-steaming and nine-sun-drying |
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Application publication date: 20200804 |