CN111466474A - Liuzhong hawthorn fruit paste and preparation method thereof - Google Patents
Liuzhong hawthorn fruit paste and preparation method thereof Download PDFInfo
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Classifications
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- A—HUMAN NECESSITIES
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- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/48—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing plants or parts thereof, e.g. fruits, seeds, extracts
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/364—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
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- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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- A61K2236/30—Extraction of the material
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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Abstract
The invention discloses a six-component and Chinese hawthorn paste and a preparation method thereof. The six-component Chinese hawthorn paste comprises hawthorn, endothelium corneum gigeriae galli, poria cocos, orange peel, polygonatum odoratum and fructus amomi. The invention has obvious functions of invigorating spleen and promoting digestion, and the formula is refined, and the process can be used for large-scale production.
Description
Technical Field
The invention belongs to the technical field of food, and particularly relates to Liuzhong hawthorn paste and a preparation method thereof.
Background
With the higher modern living standard, the diets of children are more diversified, and greasy meat foods or various fried foods are not lacked. However, people are more and more convenient to go out, and the modern life style easily causes unbalanced ingestion and consumption, so that more and more children become weak spleen qi, phlegm dampness is accumulated in the interior, absorption and digestion of water in the body cannot be completely balanced, the water in the body stays in the body to cause diseases, and all damp and swollen are all characterized in that the spleen is in the middle energizer to ascend, descend and gasify, food stagnation and phlegm are accumulated, the spleen and stomach are internally trapped in the body to cause gasification, and the symptoms are anorexia, abdominal distension, loose stool, body weakness and obesity, limbs stagnation, sleepiness, pale tongue, swollen tongue, white greasy tongue coating, soft and soft, edema, chest distress and the like.
At present, most of the used medicines for regulating qi, strengthening spleen, eliminating dampness and eliminating phlegm mainly comprise western medicines, the western medicines bring about the result of degeneration and medicine resistance of body functions, so that the body can generate adverse reactions, the symptoms are treated but not the root causes, the fundamental treatment cannot be obtained, and the children's body development can be influenced to a certain extent. Sometimes, the symptom is not obvious, and the medicine interference is not needed, and the intervention can be carried out through the medicine-food homologous substances.
Disclosure of Invention
In order to solve the problems in the prior art, the invention combines the formula of the invention by taking substances in a medicine-food homologous list as raw materials and combining a traditional Chinese medicine formula mechanism. Haw is used as the monarch, has sour and strong flavor, is good at eliminating the accumulation of fishy and mutton smell and greasy food, and removes stasis and stagnation. The ministerial drug takes the endothelium corneum gigeriae galli as the essential drug for digesting stasis, and is a wonderful product for strengthening and tonifying spleen and stomach, and the spleen and stomach are strong, and can transport and transform the efficacy of the drugs to digest stasis. The two herbs are used together to relieve intestinal and gastric stagnation. Food stagnation is easy to block qi, generate dampness and dissipate heat, while the spleen likes dryness and dislikes dampness, so the tuckahoe is used as the ministerial drug to strengthen the spleen and promote diuresis, regulate the middle and stop diarrhea; fructus amomi is added to eliminate dampness and activate the spleen; the accumulation of qi stagnation, which is caused by excessive phlegm stagnation, is assisted by orange peel, so as to regulate qi, eliminate dampness, harmonize stomach and arrest vomiting; for children's young yin and young yang, it is easy to transform heat and body fluid deficiency, and it is combined with Yu Zhu, which is sweet and cold in nature and flavor, and can nourish yin and moisten dryness, and promote fluid production to quench thirst. The compatibility of the medicines can lead to digestion and digestion retention, stomach qi harmonizing, heat clearing and dampness removing, and all symptoms can be removed automatically. The herbal beverage which meets the modern technological standard, is convenient to take and delicious and has the functions of tonifying spleen and promoting digestion is prepared by combining the paste formula process.
Specifically, the invention adopts the following technical scheme:
A six-component Chinese medicinal ointment is prepared from fructus crataegi, endothelium corneum Gigeriae Galli, Poria, pericarpium Citri Tangerinae, rhizoma Polygonati Odorati and fructus Amomi.
Preferably, the six-component and Chinese hawthorn paste comprises the following components in parts by weight:
Preferably, the hawthorn, the endothelium corneum gigeriae galli, the poria cocos, the orange peel, the polygonatum odoratum and the fructus amomi are prepared into extractum through the processes of extracting, concentrating and collecting the extractum.
Preferably, the weight of the extract is 50-65% of the weight of the original raw materials.
Preferably, the six-and-medium hawthorn paste also comprises high fructose corn syrup.
Preferably, the weight ratio of the extract to the high fructose corn syrup is (3-4) to (6-7).
The invention also provides a preparation method of the six-component and Chinese hawthorn paste, which comprises the following steps:
(1) Mixing fructus crataegi, endothelium corneum Gigeriae Galli, Poria, pericarpium Citri Tangerinae, rhizoma Polygonati Odorati and fructus Amomi at a certain ratio;
(2) Extracting the mixed raw materials, concentrating, and making into extract;
(3) Boiling and curing the high fructose corn syrup;
(4) Mixing the extract and the high fructose corn syrup according to a ratio to prepare the six-component Chinese hawthorn paste.
Preferably, the specific process of the step (2) is as follows: extracting the mixed raw materials with water for several times, sieving to obtain filtrate, heating, concentrating under reduced pressure, collecting extract until the content of soluble solid is 40-60%, and sieving.
Preferably, the cooking and curing temperature in the step (3) is 110-120 ℃.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions of the embodiments of the present invention will be clearly and completely described below. It is to be understood that the embodiments described are only a few embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the described embodiments of the invention without any inventive step, are within the scope of protection of the invention.
Unless defined otherwise, technical or scientific terms used herein shall have the ordinary meaning as understood by one of ordinary skill in the art to which this invention belongs.
The products of the examples and the comparative examples in the embodiment of the invention are prepared by mixing, extracting, concentrating and paste-collecting the raw materials to prepare extractum, and then blending and mixing the extractum with high fructose corn syrup.
The specific extraction, concentration and paste collection process comprises the following steps:
Putting the mixed raw materials into an extraction tank for extraction, wherein the extraction parameters are as follows: 10 times of water, 2 h/time and 2 times, sieving with 100 mesh sieve after extraction to obtain filtrate, sieving with 100 mesh sieve, collecting paste to the end point, and sieving with 100 mesh sieve for use. Concentration parameters: the pressure is-0.06 to-0.08 MPa, and the temperature is 65 to 70 ℃. And (4) finishing the paste collection: relative density 1.17-1.19(100 deg.C), and soluble solid 40-60% (20 deg.C).
The specific curing process is as follows:
Decocting the high fructose corn syrup in a pot with slow fire to the end point for later use. The boiling temperature is 110 ℃, and the end point is that the color of the syrup is yellowish.
The product is 1000 bags of dosage, and the use suggestion is as follows: 1-2 bags per day, 7.5 g/bag.
Example 1: the formula components of a six-component Chinese hawthorn paste (called as 'Q component') are shown in the following table. Raw materials: hawthorn fruit, orange peel, fructus amomi, endothelium corneum gigeriae galli, poria cocos, radix polygonati officinalis
Comparative example 1: the formula components of a hawthorn paste (called as group A for short) are shown in the following table.
Raw materials: hawthorn fruit, orange peel and amomum fruit
Comparative example 2: a mixed paste (group B) is prepared from endothelium corneum Gigeriae Galli, Poria, and rhizoma Polygonati Odorati.
Raw materials: endothelium corneum Gigeriae Galli, Poria, rhizoma Polygonati Odorati
[ animal Experimental validation ]
1. Laboratory animal
ICR mice, weight 18-22 g, SD rats, body weight 120-150 g. Controlling the temperature of the animal room at 20-25 ℃, and controlling the relative humidity: 45% -55%, and can freely absorb water and eat.
2. Reagent and apparatus
Sixthly, Chinese hawthorn paste, compound diphenoxylate, Chinese ink, Arabic gum, hydrochloric acid, a triangular flask, an electronic balance, surgical scissors, a straight ruler and the like.
3. Principle of experiment
The gastrointestinal tract is an organ for the intake, digestion and absorption of nutrients, and the digestion of food is mainly completed by the movement and the secretion of digestive enzymes. If the product has a regulatory effect on this or several stages, it may have a digestive function promoting effect.
4. Experimental project and data processing method
The animal experiment for promoting digestive function comprises the experiments of rat body weight, body weight gain, food intake and food utilization rate; small intestine exercise experiments; and (4) measuring digestive enzymes.
Processing with SPSS 22.0 software. The data are presented as mean ± standard deviation and the comparisons between groups are performed using independent samples, t-test.
4.1. Body weight, body weight gain, food intake and food availability
4.1.1 Experimental methods
40 SD rats are divided into an experimental group with different compositions (A group comprises hawthorn, orange peel and fructus amomi, B group comprises endothelium corneum gigeriae galli, poria cocos, radix polygonati officinalis, Q group comprises six Chinese hawthorn paste and Chinese hawthorn paste) and a negative control group, wherein a test sample is orally administered, and the administration dosage of the drug group is as follows: the drug concentration was 0.75g/ml, and mice were dosed with 0.2ml/20g, and body weight and food intake were measured 2 times per week for an experimental period of 30 days. At the end of the experiment, body weight gain, food intake and food availability were calculated.
4.1.2 results of the experiment
The experimental results show that: compared with a negative control group (distilled water), the A, B, Q group has no significant difference in promoting gastric secretion of rats, improving pepsin amount and pepsin activity. Therefore, the result of the test was judged to be negative.
Specific results are shown in table 1:
TABLE 1 influence of lack of taste of LIUZHONGSHANZHA paste on body weight, body weight gain, food intake and food utilization 
Remarking: p < 0.05 in comparison with negative control group
4.2. Small intestine exercise experiment
4.2.1 Experimental methods
60 ICR mice are divided into different formula experimental groups (A group is hawthorn, orange peel and fructus amomi; B group is endothelium corneum gigeriae galli, poria cocos and radix polygonati officinalis; Q group is six-Chinese hawthorn paste), a blank control group and a model control group, wherein the model control group is molded by compound diphenoxylate. Ink plus gum arabic was used as the indicator. Test samples were administered orally, drug groups administered dose: the drug concentration was 0.75g/ml, and mice were dosed with 0.2ml/20 g. Experiment period 30 d. After the experiment is finished, the water is not forbidden for 16 hours, the test sample or distilled water is given to each experimental group and each blank and model control group once again on the day of measurement, the compound diphenoxylate (0.025% -0.05%) is given to each experimental group and each model control group after 30 minutes, the distilled water is given to each blank control group, the indicator is given to each group after 30 minutes, the neck is cut off after 25 minutes, and the animal is killed, and the ink propulsion rate is calculated.
The ink propulsion rate was calculated as follows:
4.2.2 results of the experiment
The experimental results show that: compared with a blank control group (distilled water), the ink propulsion rate of the model control group is obviously reduced, and the difference is significant, which indicates that the modeling is successful; compared with the model control group, the group A and the group Q can promote the ink propulsion rate and have significant difference, and in addition, the significant difference of the group Q is lower than that of the group Q, so that the group Q can promote the ink propulsion rate more significantly than that of the group A. Therefore, the test result is judged to be positive.
Specific results are shown in table 2:
TABLE 2 influence of lack of taste of LIUZHONGSHANZHA paste on small intestine movement of mice 
Remarking: comparison with blank group #P is less than 0.05, compared with the model group *P＜0.05
4.3. Determination of digestive enzymes
4.3.1 Experimental methods
SD rat 40 is divided into experimental groups with different compositions (A group: hawthorn, orange peel and fructus amomi; B group: endothelium corneum gigeriae galli, poria cocos, polygonatum odoratum and Q group: six and medium hawthorn paste) and a negative control group, wherein a tested sample is orally administered, the drug concentration is 0.75g/ml, the drug administration is carried out on mice according to 0.2ml/20g, the experimental period is 30d, animals of each group are fasted for 24 hours before the experiment is finished, gastric juice discharged within a certain time is collected by adopting a ether anesthesia rat pylorus ligation method, the amount of the gastric juice within a unit time is measured, the gastric juice 1m L is taken and put into a triangular flask of 50m L, 0.05 mol/L hydrochloric acid solution 15m L is added for shaking, two freshly made protein tubes are put into the flask, the flask openings are plugged, the constant temperature box is incubated for 24 hours at 37 ℃, the protein tubes are taken out, the lengths (mm) of transparent parts at two ends of the protein tubes are measured by a ruler, and the average value at four ends.
Pepsin Activity Unit (. mu./m L) -mean length of clear portion of tetrapod protein tube 2×16
pepsin output (μ/h) pepsin activity × gastric fluid volume per hour
4.3.2 results of the experiment
The experimental results show that: compared with a negative control group (distilled water), the group Q can improve the pepsin amount and the pepsin activity, and has obvious difference. Therefore, the test result is judged to be positive.
Specific results are shown in table 3:
TABLE 3 influence of lack of taste of LIUZHONGSHANZHA paste on digestive enzymes in rats 
Remarking: p < 0.05 in comparison with negative control group
4.4 conclusion of the experiment
(1) Group A: the ink propulsion rate was significantly different compared to the model set; compared with a negative control group, the digestive enzyme experiment has no significant difference;
(2) Group B: compared with a model group, the ink propulsion rate has no significant difference; compared with a negative control group, the digestive enzyme experiment has no significant difference;
(3) Group Q: the ink propulsion rate was significantly different compared to the model set; compared with a negative control group, the digestive enzyme experiment has significant difference;
In conclusion, the formula of group Q is the formula of group A and the formula of group B, but the effect of group Q is better than that of group A and group B (see the table below for details)
Group Q formula (Liuzhong hawthorn fruit paste), wherein two test results in 3 tests are positive, and the formula can be judged to have digestion promoting effect
Effect attached watch
The above description of the embodiments is only intended to facilitate the understanding of the method of the invention and its core ideas. It should be noted that, for those skilled in the art, it is possible to make various improvements and modifications to the present invention without departing from the principle of the present invention, and those improvements and modifications also fall within the scope of the claims of the present invention.
Claims (9)
1. The six-component Chinese hawthorn paste is characterized by comprising hawthorn, endothelium corneum gigeriae galli, poria cocos, orange peel, radix polygonati officinalis and fructus amomi.
2. The six-and-medium hawthorn fruit paste as claimed in claim 1, which is characterized by comprising the following components in parts by weight:
3. The Liuzhong hawthorn fruit paste as claimed in claim 2, wherein the hawthorn fruit, the endothelium corneum gigeriae galli, the poria cocos, the orange peel, the polygonatum odoratum and the fructus amomi are prepared into an extract through extraction, concentration and paste collection processes.
4. The six-and-medium hawthorn fruit paste as claimed in claim 3, wherein the weight of the extract is 50-65% of the weight of the original raw materials.
5. The six-and-medium hawthorn fruit paste as claimed in claim 4, wherein the six-and-medium hawthorn fruit paste further comprises high fructose corn syrup.
6. The Liuzhong hawthorn fruit paste as claimed in claim 5, wherein the weight ratio of the extract to the high fructose corn syrup is (3-4) to (6-7).
7. The preparation method of the six-and-medium hawthorn fruit paste as claimed in claim 6, which is characterized by comprising the following steps:
(1) Mixing fructus crataegi, endothelium corneum Gigeriae Galli, Poria, pericarpium Citri Tangerinae, rhizoma Polygonati Odorati and fructus Amomi at a certain ratio;
(2) Extracting the mixed raw materials, concentrating, and making into extract;
(3) Boiling and curing the high fructose corn syrup;
(4) Mixing the extract and the high fructose corn syrup according to a ratio to prepare the six-component Chinese hawthorn paste.
8. The preparation method according to claim 7, wherein the specific process of the step (2) is as follows: extracting the mixed raw materials with water for several times, sieving to obtain filtrate, heating, concentrating under reduced pressure, collecting extract until the content of soluble solid is 40-60%, and sieving.
9. The method as claimed in claim 7, wherein the cooking and aging temperature of the step (3) is 110-120 ℃.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109198538A (en) * | 2018-08-20 | 2019-01-15 | 广州初品信息科技有限公司 | A kind of formula and preparation method of six object cream of hawthorn |
| CN109893637A (en) * | 2017-12-11 | 2019-06-18 | 新昌县新梦想教育信息咨询有限公司 | Stomach strengthening and digestion promoting Chinese herbal medicine |
| CN110013533A (en) * | 2019-04-12 | 2019-07-16 | 杭州胡庆余堂天然食品有限公司 | A kind of dual-purpose of drug and food children special-purpose cream taste and preparation method thereof with nourishing the stomach appetite-stimulating and indigestion-relieving effect |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109893637A (en) * | 2017-12-11 | 2019-06-18 | 新昌县新梦想教育信息咨询有限公司 | Stomach strengthening and digestion promoting Chinese herbal medicine |
| CN109198538A (en) * | 2018-08-20 | 2019-01-15 | 广州初品信息科技有限公司 | A kind of formula and preparation method of six object cream of hawthorn |
| CN110013533A (en) * | 2019-04-12 | 2019-07-16 | 杭州胡庆余堂天然食品有限公司 | A kind of dual-purpose of drug and food children special-purpose cream taste and preparation method thereof with nourishing the stomach appetite-stimulating and indigestion-relieving effect |
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