CN111388133A - Experimental mouse fixing device that uses - Google Patents

Experimental mouse fixing device that uses Download PDF

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Publication number
CN111388133A
CN111388133A CN202010104104.2A CN202010104104A CN111388133A CN 111388133 A CN111388133 A CN 111388133A CN 202010104104 A CN202010104104 A CN 202010104104A CN 111388133 A CN111388133 A CN 111388133A
Authority
CN
China
Prior art keywords
box body
fixing device
hole
box
baffle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202010104104.2A
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Chinese (zh)
Inventor
郭良清
张珊珊
方媛
李瑶
钱宇洁
齐琦
王文婷
杨旭
韩晓春
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
Original Assignee
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Affiliated Hospital of Shandong University of Traditional Chinese Medicine filed Critical Affiliated Hospital of Shandong University of Traditional Chinese Medicine
Priority to CN202010104104.2A priority Critical patent/CN111388133A/en
Publication of CN111388133A publication Critical patent/CN111388133A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D3/00Appliances for supporting or fettering animals for operative purposes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/08Radiation
    • A61L2/10Ultraviolet radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L9/00Disinfection, sterilisation or deodorisation of air
    • A61L9/16Disinfection, sterilisation or deodorisation of air using physical phenomena
    • A61L9/18Radiation
    • A61L9/20Ultraviolet radiation

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Husbandry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Eye Examination Apparatus (AREA)

Abstract

The invention provides a fixing device for a white mouse for a test, which comprises a box body, wherein the edge of the inner side of a box cover is connected with a handle through a plurality of hinges, a plurality of male buckles are fixedly connected with the outer side of the box cover, a plurality of female buckles matched with the male buckles are fixedly connected with the opening position of the upper end of the box body, a through hole is arranged on the outer side of the bottom of the box body, a cleaning box is arranged inside the through hole, a grating plate is arranged on the inner side of the box body at the upper end of the through hole, two clamping grooves are arranged on the inner side plate of the box body, two sides of a feeding groove are respectively inserted into the clamping grooves, a plurality of air holes are arranged on the box cover, and a plurality of fixing cylinders are communicated with the front side plate of the box body. The metal belt is automatically tightened to the position of the chest and abdomen of the mouse, so that the automatic fixation of the mouse is realized.

Description

Experimental mouse fixing device that uses
Technical Field
The invention is used in the technical field of mouse experimental devices, and particularly relates to a mouse fixing device for experiments.
Background
The white mouse is widely used for experiments and tests on safety, toxicity, efficacy and the like of food, cosmetics, medicines, biological products, industrial products, medicine, life science and the like; the specific reason why the white mouse was selected as the experimental subject was analyzed as follows:
1) the gene sequence of mice among mice is comparable to that of humans;
2) the biological significance of the experiment special white mouse is larger, the breeding method of the pure mouse forms a fixed flow after hundred years of exploration, and the bred mouse almost has no individual difference;
3) the quantity is sufficient, although the orangutan and the like are more similar to the human body, the quantity is rare, the quantity of mice is large, and the requirement of a huge number of experimental objects required by the experiment can be met.
Therefore, mice are often selected as subjects for experiments.
The fixing device for the white mouse for the experiment is provided by the invention, aiming at the problem that the white mouse needs to be fixed, the operation such as subsequent intravenous injection and feeding is convenient to carry out according to the experiment requirement, the white mouse needs to be fixed before the experiment is carried out, the four limbs of the white mouse are bound by an elastic rope in the traditional fixing mode, the fixing mode is labor-consuming in operation and high in operation difficulty, the death or disability rate of the white mouse after the experiment is high, and the experiment result can be possibly affected.
Disclosure of Invention
Aiming at the defects that the operation difficulty of a fixing device for a white mouse test in the prior art is high and the white mouse is easy to cause disability and even death, the invention mainly aims to provide the fixing device for the white mouse for the test.
In order to solve the technical problems, the invention provides a fixing device for a test white mouse, which comprises a box body, wherein the edge of the inner side of a box cover is connected with a handle through a plurality of hinges, a plurality of male buckles are fixedly connected to the outer side of the box cover, a plurality of female buckles matched with the male buckles are fixedly connected to the opening position of the upper end of the box body, a through hole is arranged on the outer side of the bottom of the box body, a cleaning box is arranged inside the through hole, a grating plate is arranged on the inner side of the box body at the upper end of the through hole, two clamping grooves are arranged on the inner side plate of the box body, two sides of a feeding groove are respectively inserted into the clamping grooves, a plurality of air holes are arranged on the box cover, a plurality of fixing cylinders are communicated to the front side plate of the box body, a baffle plate capable of being pulled up and down is, the elastic piece is connected with a metal belt, two sides of the metal belt penetrate through the rope penetrating hole in the fixed cylinder respectively, the front baffle extends into the clamping groove, two sides of the front baffle are connected with the movable end of the elastic piece through a connecting rope respectively, an end cover is in threaded connection with an opening at the outer side of the fixed cylinder, and a plurality of side air holes are formed in the end cover.
Further, the end cover and the fixed cylinder are made of transparent glass or plastic materials.
Furthermore, the front end and the rear end of the fixed cylinder are both in a horn mouth shape, and the two ends of the outer diameter are large and the middle is small.
Furthermore, an ultraviolet sterilization lamp is fixedly connected to the inner side of the box cover.
Furthermore, the elastic sheet is made of a sheet spring steel material and is of an arch structure.
Furthermore, the front baffle is of a disc structure with holes, and the width of the clamping groove is 2-3 times of the thickness of the front baffle.
Furthermore, a hygrothermograph is arranged in the box body.
Furthermore, a plurality of the fixed cylinders are respectively provided with an experiment group number label pasting area.
The invention has the beneficial effects that:
1) the mouse fixing device designed by the invention does not need to bind the mouse manually, avoids the defect that the mouse is easy to bite in the manual binding process, only needs to use food to induce the mouse to enter the fixing cylinder, and the metal belt is automatically tightened to the position of the chest and abdomen of the mouse under the elastic action of the elastic sheet to realize the automatic fixing of the mouse;
2) the elastic piece has elasticity, and the metal belt for fixing has larger width compared with the traditional elastic rubber band, has small damage to the white mouse, is not easy to cause the white mouse to cause disability, and has high use safety.
Drawings
The invention is further illustrated with reference to the following figures and examples.
FIG. 1 is a front view structural diagram of the present invention.
Fig. 2 is a left side view structural diagram of the present invention.
Fig. 3 is a right view structural diagram of the present invention.
Fig. 4 is a top view structural diagram of the present invention.
Fig. 5 is a sectional structural view a-a in fig. 4 of the present invention.
Fig. 6 is a three-dimensional structural view of the present invention.
Fig. 7 is a three-dimensional axial structure view of the present invention.
In the figure, the position of the upper end of the main shaft,
1-box cover, 2-handle, 3-male buckle, 4-opening, 5-female buckle, 6-baffle, 7-elastic sheet, 8-metal belt, 9-rope-threading hole, 10-front baffle, 11-clamping groove, 12-end cover, 13-cleaning box, 14-through hole, 15-box body, 16-air hole, 17-side air hole, 18-fixing cylinder, 19-ultraviolet sterilizing lamp, 20-grating plate, 21-clamping groove and 22-feeding groove.
Detailed Description
The present invention is further illustrated by the following figures and examples, which include, but are not limited to, the following examples.
In order to achieve the purpose, the technical scheme adopted by the invention is as follows:
as shown in figures 1 to 7, the fixing device for the laboratory white mouse comprises a box body 15 with a handle 2 connected with the inner edge of a box cover 1 through a plurality of hinges, a plurality of male buckles 3 fixedly connected with the outer side of the box cover 1, a plurality of female buckles 5 matched with the male buckles 3 fixedly connected with the opening 4 of the upper end of the box body 15, a through hole 14 arranged on the outer side of the bottom of the box body 15, a cleaning box 13 arranged inside the through hole 14, a grating plate 20 arranged on the inner side of the box body 15 on the upper end of the through hole 14, two clamping grooves 21 arranged on the inner side plate of the box body 15, two sides of a feeding groove 22 respectively inserted into the clamping grooves 21, a plurality of vent holes 16 arranged on the box cover 1, a plurality of fixed cylinders 18 communicated with the front side plate of the box body 15, a baffle 6 capable of being pulled up and down arranged in the opening of the left side of the fixed cylinders 18, a rope passing hole 9 and a, two sides of the metal belt 8 respectively penetrate through the rope through holes 9 in the fixed cylinder 18, the front baffle 10 extends into the clamping groove 11, two sides of the front baffle 10 are respectively connected with the movable end of the elastic sheet 7 through a connecting rope, the opening of the outer side of the fixed cylinder 18 is in threaded connection with an end cover 12, and the end cover 12 is provided with a plurality of side air holes 17.
When the experiment is not carried out, the white mouse can be raised in the box body 15, two clamping grooves 21 are fixed on the side panel of the box body 15, two sides of the feeding groove 22 are respectively inserted into the clamping grooves 21, food and drinking water are added in the feeding groove 22, a grating plate 20 is placed on a boss in the box body 15, excrement and urine discharged by the white mouse can enter the cleaning box 13 through the grating plate 20, the excrement and urine of the white mouse can be conveniently cleaned, the grating plate 20 is kept dry, the feeding is convenient, when the experiment is carried out in the box body 15, only the baffle plate 6 is opened and is drawn away from the fixed cylinder 18, the end cover 12 is opened, then the front end of the front baffle plate 10 is placed with attracting food and screwed on the end cover 12, the front baffle plate 10 is made of transparent plastic material, the through hole is arranged at the upper end, the white mouse can penetrate into the fixed cylinder 18 under the attraction of the food, the attraction of the metal belt 8 annular ring penetrates through the metal belt, the front baffle plate 10 is, preceding baffle 10 can be smoothly through draw-in groove 11, the connection rope in preceding baffle 10 both sides is connected on flexure strip 7, flexure strip 7 is under self elastic action, the expansion end upwards lifts up, pulling strap 8 tightens up, make strap 8 bind the chest abdomen portion at the mice, flexure strip 7 self has elasticity can not cause the serious harm of health to the mice, and 18 front and back ends of a fixed cylinder are the horn mouth shape, little in the middle of the external diameter both ends are big, the intermediate position internal diameter is little, be convenient for fix the mice, the front end opening is the horn mouth shape, be convenient for operate according to the experimental requirement.
Furthermore, the end cover 12 and the fixed cylinder 18 are made of transparent glass or plastic materials, so that the experiment dynamics of the white mouse can be observed in real time conveniently, and the experiment operation is convenient.
Furthermore, the front end and the rear end of the fixed cylinder 18 are both in a horn mouth shape, the two ends of the outer diameter are large, the middle of the outer diameter is small, so that a mouse can conveniently drill into the fixed cylinder 18, and the end cover 12 is opened to facilitate the intravenous injection, the drug filling and other operations of the mouse.
Further, an ultraviolet sterilizing lamp 19 is fixedly connected to the inner side of the case cover 1, and the ultraviolet sterilizing lamp 19 can be used for sterilizing water, air, clothes and the like by utilizing ultraviolet sterilization emitted by the ultraviolet sterilizing lamp 19.
Furthermore, the elastic sheet 7 is made of a sheet spring steel material and is of an arch structure, the arch structure is large in elasticity, the sheet spring steel is large in elasticity, the metal belt 8 can be tensioned by the aid of the elasticity of the elastic sheet 7, the metal belt 8 is automatically tensioned and bound to the chest and abdominal cavity of the white mouse, and the elastic sheet 7 is elastic and cannot cause serious harm to the body of the white mouse.
Furthermore, the front baffle 10 is of a disc structure with holes, the width of the clamping groove 11 is 2-3 times of the thickness of the front baffle 10, when a white mouse pushes the front baffle 10, the front baffle 10 can smoothly pass through the clamping groove 11, the phenomenon that the front baffle 10 is blocked is avoided, and the action is flexible and reliable.
Further, box body 15 internally mounted has a warm and humid acidimeter, can detect the temperature and the humidity of box body 15 internal environment, the temperature of being convenient for, humidity variable.
The technical solutions of the present invention or similar technical solutions designed by those skilled in the art based on the teachings of the technical solutions of the present invention are all within the scope of the present invention.

Claims (7)

1. The experimental mouse fixing device is characterized by comprising a box body (15) with a handle (2) and connected with the inner side edge of a box cover (1) through a plurality of hinges, a plurality of male buckles (3) are fixedly connected to the outer side of the box cover (1), a plurality of female buckles (5) matched with the male buckles (3) are fixedly connected to the upper end opening (4) of the box body (15), a through hole (14) is formed in the outer side of the bottom of the box body (15), a cleaning box (13) is arranged inside the through hole (14), a grating plate (20) is arranged on the inner side of the box body (15) at the upper end of the through hole (14), two clamping grooves (21) are formed in the inner side plate of the box body (15), two sides of a feeding groove (22) are respectively inserted into the clamping grooves (21), a plurality of air holes (16) are formed in the box cover (1), and a plurality of fixing cylinders (18) are communicated, be equipped with baffle (6) of pull from top to bottom in the opening of solid fixed cylinder (18) left side, baffle (6) outside is equipped with a rope handling hole (9), a draw-in groove (11) in proper order, and flexure strip (7) left side stiff end is fixed on solid fixed cylinder (18), be connected with a strap (8) on flexure strip (7), strap (8) both sides are passed respectively on solid fixed cylinder (18) rope handling hole (9), preceding baffle (10) stretch into inside draw-in groove (11), preceding baffle (10) both sides are connected through a connecting rope respectively flexure strip (7) expansion end, solid fixed cylinder (18) outside opening part threaded connection has an end cover (12), be equipped with a plurality of side bleeder vents (17) on end cover (12).
2. The experimental mouse fixing device according to claim 1, wherein the end cap (12) and the fixing cylinder (18) are made of transparent glass or plastic materials.
3. The experimental mouse fixing device according to claim 1 or 2, wherein the front and rear ends of the fixing cylinder (18) are formed in a bell shape, and the outer diameter is larger at both ends and smaller at the middle.
4. The experimental mouse fixing device according to claim 1, wherein an ultraviolet sterilizing lamp (19) is fixed to the inner side of the case cover (1).
5. The experimental mouse fixing device according to claim 1, wherein the elastic piece (7) is made of a sheet spring steel material and has an arch structure.
6. The experimental white mouse fixing device according to claim 1, wherein the front baffle (10) is a perforated disc structure and the width of the slot (11) is 2-3 times the thickness of the front baffle (10).
7. The experimental mouse fixing device according to claim 1, wherein a thermo-hygrometer is installed inside the case (15).
CN202010104104.2A 2020-02-18 2020-02-18 Experimental mouse fixing device that uses Pending CN111388133A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010104104.2A CN111388133A (en) 2020-02-18 2020-02-18 Experimental mouse fixing device that uses

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202010104104.2A CN111388133A (en) 2020-02-18 2020-02-18 Experimental mouse fixing device that uses

Publications (1)

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CN111388133A true CN111388133A (en) 2020-07-10

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115968798A (en) * 2022-12-30 2023-04-18 生态环境部南京环境科学研究所 Experiment box for animal toxicology experiments and using method thereof

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Publication number Priority date Publication date Assignee Title
US20080168948A1 (en) * 2007-01-11 2008-07-17 Starr Life Sciences Corp. Small animal restraining device with non-traumatic animal loading device
CN203634326U (en) * 2013-12-19 2014-06-11 中国人民解放军第三军医大学第一附属医院 Mouse fixation cylinder
CN105662633A (en) * 2016-01-06 2016-06-15 西安医学院 Experiment device and system for checking degree of cerebral apoplexy lower limb paralysis and application method
CN106037983A (en) * 2016-07-11 2016-10-26 中国环境科学研究院 Fixing device for rat oral and nasal inhalation exposure experiment
CN206323950U (en) * 2016-12-22 2017-07-14 上海中医药大学附属岳阳中西医结合医院 A kind of pregnant mouse rearging cage
US20170202205A1 (en) * 2016-01-18 2017-07-20 Guodong Wu Mouse trap
CN206391046U (en) * 2016-10-21 2017-08-11 昆明医科大学 A kind of fixing device for testing white mouse
CN206462155U (en) * 2017-02-07 2017-09-05 温州市中心医院 A kind of biology uses mouse experimental box
CN206821621U (en) * 2017-06-26 2018-01-02 重庆三峡医药高等专科学校 A kind of multi-functional big mouse cage
CN206821806U (en) * 2017-06-29 2018-01-02 李新 A kind of small white mouse cage trap
CN206852677U (en) * 2016-12-12 2018-01-09 湖南师范大学 A kind of rat fixing device
CN107898528A (en) * 2017-12-17 2018-04-13 李世川 A kind of full-automatic fixing device
CN208838221U (en) * 2017-11-15 2019-05-10 山东农业大学 It is a kind of for prevent mouse scratching back buttocks wound Simple fixing device
CN208958397U (en) * 2018-09-13 2019-06-11 王凤璐 A kind of animal doctor's special for treating shield cage
CN209933050U (en) * 2019-01-29 2020-01-14 赵恩聪 Novel mouse is fixed device

Patent Citations (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080168948A1 (en) * 2007-01-11 2008-07-17 Starr Life Sciences Corp. Small animal restraining device with non-traumatic animal loading device
CN203634326U (en) * 2013-12-19 2014-06-11 中国人民解放军第三军医大学第一附属医院 Mouse fixation cylinder
CN105662633A (en) * 2016-01-06 2016-06-15 西安医学院 Experiment device and system for checking degree of cerebral apoplexy lower limb paralysis and application method
US20170202205A1 (en) * 2016-01-18 2017-07-20 Guodong Wu Mouse trap
CN106037983A (en) * 2016-07-11 2016-10-26 中国环境科学研究院 Fixing device for rat oral and nasal inhalation exposure experiment
CN206391046U (en) * 2016-10-21 2017-08-11 昆明医科大学 A kind of fixing device for testing white mouse
CN206852677U (en) * 2016-12-12 2018-01-09 湖南师范大学 A kind of rat fixing device
CN206323950U (en) * 2016-12-22 2017-07-14 上海中医药大学附属岳阳中西医结合医院 A kind of pregnant mouse rearging cage
CN206462155U (en) * 2017-02-07 2017-09-05 温州市中心医院 A kind of biology uses mouse experimental box
CN206821621U (en) * 2017-06-26 2018-01-02 重庆三峡医药高等专科学校 A kind of multi-functional big mouse cage
CN206821806U (en) * 2017-06-29 2018-01-02 李新 A kind of small white mouse cage trap
CN208838221U (en) * 2017-11-15 2019-05-10 山东农业大学 It is a kind of for prevent mouse scratching back buttocks wound Simple fixing device
CN107898528A (en) * 2017-12-17 2018-04-13 李世川 A kind of full-automatic fixing device
CN208958397U (en) * 2018-09-13 2019-06-11 王凤璐 A kind of animal doctor's special for treating shield cage
CN209933050U (en) * 2019-01-29 2020-01-14 赵恩聪 Novel mouse is fixed device

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115968798A (en) * 2022-12-30 2023-04-18 生态环境部南京环境科学研究所 Experiment box for animal toxicology experiments and using method thereof

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Application publication date: 20200710