CN115968798A - Experiment box for animal toxicology experiment and using method thereof - Google Patents
Experiment box for animal toxicology experiment and using method thereof Download PDFInfo
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- 241000700159 Rattus Species 0.000 claims abstract description 67
- 238000007789 sealing Methods 0.000 claims description 19
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- 230000002093 peripheral effect Effects 0.000 claims description 8
- 238000009423 ventilation Methods 0.000 claims description 8
- 239000003814 drug Substances 0.000 claims description 7
- 210000003608 fece Anatomy 0.000 claims description 4
- 239000011521 glass Substances 0.000 claims description 3
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- 230000000694 effects Effects 0.000 abstract description 17
- 238000002347 injection Methods 0.000 description 9
- 239000007924 injection Substances 0.000 description 9
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- 229940079593 drug Drugs 0.000 description 6
- 238000010586 diagram Methods 0.000 description 5
- 238000004659 sterilization and disinfection Methods 0.000 description 4
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- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 230000000249 desinfective effect Effects 0.000 description 1
- 230000003100 immobilizing effect Effects 0.000 description 1
- 238000011173 large scale experimental method Methods 0.000 description 1
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- 230000002110 toxicologic effect Effects 0.000 description 1
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Abstract
本发明公开了一种动物毒理实验用实验箱及其使用方法,包括实验箱本体,所述实验箱本体的顶部固定连接有固定盒,所述固定盒的前端固定连接有固定板,所述固定板内腔的上端活动连接有第一夹板,所述第一夹板的内腔设置有第二夹板;本发明通过设置实验箱本体,起到了能够对实验大鼠进行饲养观察的效果,通过设置固定盒、固定板、第一夹板、第二夹板、第一弹簧、气缸和挡板,起到了能够对实验大鼠注射时进行固定的效果,解决了由于饲养笼功能性较为单一,进行实验时还需要专门配备实验操作平台,增加了实验成本还不利于实验进展,而且肢体的固定方式效果较差,从而影响实验的进展,给实验人员带来了不便的问题。
The invention discloses an experimental box for animal toxicology experiments and a method for using the same. The upper end of the fixed plate inner cavity is movably connected with a first splint, and the inner cavity of the first splint is provided with a second splint; the present invention has the effect of being able to feed and observe the experimental rats by setting the experiment box body. The fixed box, the fixed plate, the first splint, the second splint, the first spring, the cylinder and the baffle have the effect of being able to fix the experimental rats when they are injected, and solve the problem that the feeding cage is relatively single in functionality. It also needs to be specially equipped with an experimental operation platform, which increases the cost of the experiment and is not conducive to the progress of the experiment, and the effect of the fixation method of the limbs is poor, which affects the progress of the experiment and brings inconvenience to the experimenters.
Description
技术领域technical field
本发明涉及动物毒理实验技术领域,具体为一种动物毒理实验用实验箱。The invention relates to the technical field of animal toxicology experiments, in particular to an experimental box for animal toxicology experiments.
背景技术Background technique
动物毒理实验是通过给予动物特定的物质后,观察动物的毒性反应,阐明某一化学物的毒性及其潜在危害的一种实验手段,毒理实验对保证食品、化妆品、医疗用品、药品和化学产品等安全起到重要作用,为人类对化学物质的使用作出毒理安全性评价,为制订预防措施特别及卫生标准提供理论依据,常见的实验动物有大小鼠,因饲养简单,所以是很多生物医药实验的首要选择对象,通常养殖在饲养笼里,便于实验后进行观察,实验的时候先将大小鼠或者从饲养笼里取出,放置在实验操作平台上进行实验操作,实验过程中需要给大小鼠灌喂或者注射特定药物,而大小鼠受到惊吓会出现反抗行为,为了保证药物注射顺利进行,需要先利用固定装置或者人力将动物固定,然后在注射药物,人力固定方法需要至少两人协同完成对大小鼠的固定和药物注射的操作,消耗人力资源多。Animal toxicology experiment is an experimental method to clarify the toxicity and potential harm of a certain chemical by observing the toxic reaction of animals after giving specific substances. The safety of chemical products plays an important role in evaluating the toxicological safety of the use of chemical substances by humans, and providing a theoretical basis for formulating preventive measures and hygienic standards. Common experimental animals include rats and mice. Because of the simplicity of feeding, there are many The primary choice for biomedical experiments is usually bred in a breeding cage, which is convenient for observation after the experiment. During the experiment, the rats or mice are first taken out of the breeding cage and placed on the experimental operation platform for experimental operations. During the experiment, it is necessary to give Rats are fed or injected with specific drugs, and the rats will show resistance when they are frightened. In order to ensure the smooth progress of the drug injection, it is necessary to use a fixture or manpower to fix the animal first, and then inject the drug. The manual fixation method requires the cooperation of at least two people Completing the operations of fixation and drug injection of rats and mice consumes a lot of human resources.
特别的对于实验大鼠来说,固定装置是通过绑带对实验大鼠肢体进行固定,而仅仅绑定实验大鼠肢体,实验大鼠的身体仍然会表现出反抗动作,导致固定的效果仍较差,影响实验进展,而且实验是需要进行多次分段注射,每次注射完还需要将实验大鼠放回饲养笼里,因此需要频繁的将实验大鼠转移,由于饲养笼功能性较为单一,进行实验时还需要专门配备实验操作平台,增加了实验成本还不利于实验进展,而且肢体的固定方式效果较差,从而影响实验的进展,给实验人员带来了不便。Especially for the experimental rats, the immobilization device fixes the limbs of the experimental rats through straps, but only binding the limbs of the experimental rats, the body of the experimental rats will still show resistance movements, resulting in a relatively low fixation effect. Poor, it affects the progress of the experiment, and the experiment needs to be injected several times, and the experimental rats need to be put back into the breeding cage after each injection, so the experimental rats need to be transferred frequently, because the function of the breeding cage is relatively single , It is also necessary to equip a special experimental operation platform when conducting experiments, which increases the cost of the experiment and is not conducive to the progress of the experiment, and the effect of fixing the limbs is poor, which affects the progress of the experiment and brings inconvenience to the experimenters.
发明内容Contents of the invention
本发明的目的在于提供一种动物毒理实验用实验箱,具备了方便使用的优点,解决了由于饲养笼功能性较为单一,进行实验时还需要专门配备实验操作平台,增加了实验成本还不利于实验进展,而且肢体的固定方式效果较差,从而影响实验的进展,给实验人员带来了不便的问题。The object of the present invention is to provide a kind of experimental box for animal toxicology experiment, which has the advantage of being convenient to use, and solves the problem that due to the relatively single functionality of the breeding cage, it is necessary to be specially equipped with an experimental operation platform when conducting experiments, which increases the cost of the experiment and is not sufficient. It is beneficial to the progress of the experiment, and the effect of the fixing method of the limbs is poor, which affects the progress of the experiment and brings inconvenience to the experimenters.
为实现上述目的,本发明提供如下技术方案:一种动物毒理实验用实验箱,包括实验箱本体,所述实验箱本体的顶部固定连接有固定盒,所述固定盒的前端固定连接有固定板,所述固定板内腔的上端活动连接有第一夹板,所述第一夹板的内腔设置有第二夹板,所述第二夹板的顶部固定连接有第一弹簧,所述第一弹簧远离第二夹板的一端与第一夹板的内壁固定连接,所述固定板的顶部固定连接有气缸,所述气缸的输出端贯穿至固定板的内腔并与第一夹板固定连接,所述固定盒内腔的后端活动连接有挡板,所述实验箱本体的正面通过铰链铰接有密封门,所述密封门正面上端的两侧均固定连接有锁紧单元,所述锁紧单元包括固定块,所述固定块的正面通过转轴活动连接有推杆,所述推杆表面的上端通过轴承活动连接有第一框架,所述第一框架的内腔活动连接有支撑板,所述支撑板的顶部固定连接有连接杆,所述连接杆远离支撑板的一端贯穿至第一框架的外部并固定连接有锁止环,所述实验箱本体正面上端的两侧均固定连接有挂钩,所述挂钩延伸至锁止环的内腔并与锁止环的内腔活动连接,所述连接杆位于第一框架内腔的一端套设有第二弹簧,所述第二弹簧的两端分别与第一框架和支撑板固定连接。In order to achieve the above object, the present invention provides the following technical solutions: an experimental box for animal toxicology experiments, comprising an experimental box body, the top of the experimental box body is fixedly connected with a fixed box, and the front end of the fixed box is fixedly connected with a fixed box. plate, the upper end of the inner cavity of the fixed plate is movably connected with a first splint, the inner cavity of the first splint is provided with a second splint, the top of the second splint is fixedly connected with a first spring, and the first spring One end away from the second splint is fixedly connected to the inner wall of the first splint, the top of the fixed plate is fixedly connected with a cylinder, the output end of the cylinder penetrates into the inner cavity of the fixed plate and is fixedly connected with the first splint, the fixed The rear end of the inner chamber of the box is movably connected with a baffle, and the front of the experiment box body is hinged with a sealed door, and both sides of the upper end of the front of the sealed door are fixedly connected with a locking unit, and the locking unit includes a fixed block, the front of the fixed block is movably connected with a push rod through a rotating shaft, the upper end of the push rod surface is movably connected with a first frame through a bearing, and the inner cavity of the first frame is movably connected with a support plate, and the support plate The top of the test box is fixedly connected with a connecting rod, and the end of the connecting rod away from the support plate penetrates to the outside of the first frame and is fixedly connected with a locking ring. Both sides of the upper end of the front of the experiment box body are fixedly connected with hooks. The hook extends to the inner cavity of the locking ring and is movably connected with the inner cavity of the locking ring. The connecting rod is located at one end of the inner cavity of the first frame and is provided with a second spring, and the two ends of the second spring are respectively connected to the first A frame is fixedly connected with the supporting plate.
优选的,所述第一框架内腔的两侧均开设有第一限位槽,所述第一限位槽的内腔滑动连接有第一限位块,所述第一限位块远离第一限位槽内腔的一端与支撑板固定连接。Preferably, both sides of the inner cavity of the first frame are provided with first limiting grooves, the inner cavity of the first limiting groove is slidably connected with a first limiting block, and the first limiting block is far away from the first limiting block. One end of the inner cavity of the limiting groove is fixedly connected with the support plate.
优选的,所述固定盒的顶部通过铰链铰接有密封板,所述密封板的顶部开设有透气孔。Preferably, the top of the fixed box is hinged with a sealing plate, and the top of the sealing plate is provided with air holes.
优选的,所述密封板表面的左侧固定连接有第一魔术贴,所述固定盒左侧的上端固定连接有第二魔术贴,所述第一魔术贴远离第二魔术贴的一端与第二魔术贴粘接。Preferably, the left side of the surface of the sealing plate is fixedly connected with a first Velcro, the upper end of the left side of the fixed box is fixedly connected with a second Velcro, and the end of the first Velcro away from the second Velcro is connected to the first Velcro. Two Velcro adhesive.
优选的,所述固定盒内腔后端的两侧均开设有第一滑槽,所述第一滑槽的内腔滑动连接有第一滑块,所述第一滑块远离第一滑槽内腔的一端与挡板固定连接。Preferably, both sides of the rear end of the inner cavity of the fixed box are provided with a first chute, the inner cavity of the first chute is slidably connected with a first slider, and the first slider is far away from the inner cavity of the first chute. One end of the cavity is fixedly connected with the baffle.
优选的,所述固定板内腔的两侧均开设有第二限位槽,所述第二限位槽的内腔滑动连接有第二限位块,所述第二限位块远离第二限位槽内腔的一端与第一夹板固定连接。Preferably, both sides of the inner cavity of the fixing plate are provided with a second limiting groove, and the inner cavity of the second limiting groove is slidably connected with a second limiting block, and the second limiting block is far away from the second One end of the inner cavity of the limiting groove is fixedly connected with the first splint.
优选的,所述实验箱本体内腔的上端活动连接有第二框架,所述第二框架的内腔固定连接有网片,所述实验箱本体内腔上端的两侧均开设有第二滑槽,所述第二滑槽的内腔滑动连接有第二滑块,所述第二滑块远离第二滑槽内腔的一端与第二框架固定连接。Preferably, the upper end of the inner cavity of the experiment box body is movably connected with a second frame, the inner cavity of the second frame is fixedly connected with a mesh, and the two sides of the upper end of the inner cavity of the experiment box body are provided with second slides. The inner cavity of the second sliding slot is slidably connected with a second sliding block, and the end of the second sliding block away from the inner cavity of the second sliding slot is fixedly connected with the second frame.
优选的,所述实验箱本体内腔的下端活动连接有收集盒,所述实验箱本体内腔下端的两侧均开设有第三滑槽,所述第三滑槽的内腔滑动连接有第三滑块,所述第三滑块远离第三滑槽内腔的一端与收集盒固定连接。Preferably, the lower end of the inner cavity of the experiment box body is movably connected with a collection box, and both sides of the lower end of the inner cavity of the experiment box body are provided with a third chute, and the inner cavity of the third chute is slidably connected with a first Three sliders, the end of the third slider far away from the inner chamber of the third chute is fixedly connected with the collection box.
优选的,所述实验箱本体的两侧均开设有观察孔,所述观察孔的内腔固定连接有透明玻璃,所述实验箱本体内腔的背面固定连接有换气扇,所述实验箱本体内腔的右侧固定连接有紫外线杀菌灯。Preferably, observation holes are provided on both sides of the experiment box body, transparent glass is fixedly connected to the inner cavity of the observation hole, and a ventilating fan is fixedly connected to the back of the inner cavity of the experiment box body. The right side of the cavity is fixedly connected with an ultraviolet germicidal lamp.
优选的,其使用方法包括如下步骤:Preferably, its use method comprises the following steps:
A.首先将实验大鼠放置在固定盒的内腔,将实验大鼠头颈部放置在固定板的内腔,通过外设控制器启动气缸,气缸的输出轴向下运动带动第一夹板和第二夹板通过第二限位块沿着第二限位槽的内腔向下运动,第一夹板与固定板卡合并对实验大鼠头颈部进行固定,接着将挡板通过第一滑块和第一滑槽安装在实验大鼠尾部,将密封板盖合在固定盒的顶部,拉动第一魔术贴与第二魔术贴粘接,使其对实验大鼠身体进行固定,对实验大鼠用药完成后,反之上述步骤将实验大鼠取出,放置在实验箱本体的内腔进行观察;A. First place the experimental rat in the inner cavity of the fixed box, place the head and neck of the experimental rat in the inner cavity of the fixed plate, start the cylinder through the peripheral controller, and the output shaft of the cylinder moves downward to drive the first splint and The second splint moves down along the inner cavity of the second limit groove through the second limiting block, the first splint engages with the fixed plate and fixes the head and neck of the experimental rat, and then passes the baffle through the first slider Install the first chute on the tail of the experimental rat, close the sealing plate on the top of the fixed box, pull the first Velcro and the second Velcro to make it fix the body of the experimental rat. After the medication is completed, the above-mentioned steps are reversed to take out the experimental rat and place it in the inner cavity of the experimental box body for observation;
B.将实验大鼠放置在实验箱本体内腔网片的顶部后,向上拉动密封门,使密封门对实验箱本体进行密封,然后向上推动拉动推杆,推杆带动第一框架向上运动,第一框架推动锁止环向上运动,使锁止环与挂钩卡合,然后向下按压推杆,推杆带动第一框架向下运动,第一框架向下运动时对连接杆造成挤压,使连接杆发生形变,从而使锁止环与挂钩紧密卡接,使密封门和实验箱本体进行固定;B. After placing the experimental rat on the top of the mesh in the inner cavity of the experimental box body, pull the airtight door upward to make the airtight door seal the body of the experimental box, then push and pull the push rod upward, and the push rod drives the first frame to move upward. The first frame pushes the locking ring to move upward, so that the locking ring engages with the hook, and then presses down the push rod, which drives the first frame to move downward. When the first frame moves downward, the connecting rod is squeezed, The connecting rod is deformed, so that the locking ring and the hook are tightly clamped, and the airtight door and the experiment box body are fixed;
C.通过外设控制器启动换气扇和紫外线杀菌灯,换气扇旋转产生的气流将实验箱本体内腔的异味排出,紫外线杀菌灯对实验箱本体的内腔进行消毒杀菌作业,实验大鼠的粪便通过网片落入收集盒的内腔,将收集盒通过第三滑槽和第三滑块可从实验箱本体的内腔抽出对收集盒进行清洗,向外拉动第二框架,第二框架通过第二滑块和第二滑槽的配合,可从实验箱本体的内腔取出对网片进行清洗。C. Start the ventilating fan and ultraviolet germicidal lamp through the peripheral controller, the airflow generated by the rotation of the ventilating fan will discharge the peculiar smell in the inner cavity of the experimental box body, and the ultraviolet germicidal lamp will disinfect and sterilize the inner cavity of the experimental box body. The mesh falls into the inner cavity of the collection box, and the collection box can be pulled out from the inner cavity of the experimental box body through the third chute and the third slider to clean the collection box, and the second frame is pulled outward, and the second frame passes through the second frame. The cooperation of the second slide block and the second chute can be taken out from the inner cavity of the experiment box body to clean the mesh.
与现有技术相比,本发明的有益效果如下:Compared with the prior art, the beneficial effects of the present invention are as follows:
本发明通过设置实验箱本体,起到了能够对实验大鼠进行饲养观察的效果,通过设置固定盒、固定板、第一夹板、第二夹板、第一弹簧、气缸和挡板,起到了能够对实验大鼠注射时进行固定的效果,气缸向下运动带动第一夹板向下运动,第一夹板向下运动带动第二夹板向下运动,第一夹板、第二夹板和固定板配合能够对实验大鼠的头颈部进行固定,从而防止实验大鼠在注射时受到惊吓发生反抗行为,影响实验进展,通过设置密封门,用于对实验箱本体进行密封,防止实验大鼠从实验箱本体的内腔跑出,通过固定块、推杆、第一框架、支撑板、连接杆、锁止环、挂钩和第二弹簧的配合,起到了能够对实验箱本体和密封门固定,锁止环与挂钩卡接,推杆向下运动带动第一框架向下运动,第一框架向下运动对第二弹簧进行挤压,从而能够使挂钩和锁止环紧密卡接,只需上下推拉推杆就能够实现对锁止环和挂钩的解锁,从而方便开合,进而方便拿取实验大鼠进行实验工作,解决了由于饲养笼功能性较为单一,进行实验时还需要专门配备实验操作平台,增加了实验成本还不利于实验进展,而且肢体的固定方式效果较差,从而影响实验的进展,给实验人员带来了不便的问题。The present invention has played the effect of being able to feed and observe experimental rats by setting the experimental box body, and has played a role in being able to raise and observe experimental rats by setting a fixed box, a fixed plate, a first splint, a second splint, a first spring, a cylinder and a baffle plate. The effect of immobilizing experimental rats during injection is that the downward movement of the cylinder drives the first splint to move downward, and the downward movement of the first splint drives the second splint to move downward. The head and neck of the rats are fixed to prevent the experimental rats from being frightened to resist behavior during the injection, which affects the progress of the experiment. By setting a sealed door, it is used to seal the experimental box body to prevent the experimental rats from entering the experimental box body. The inner cavity runs out, and through the cooperation of the fixed block, push rod, first frame, support plate, connecting rod, locking ring, hook and second spring, the body of the experiment box and the sealed door can be fixed, and the locking ring and the sealing door can be fixed. The hook is clamped, the push rod moves downward to drive the first frame to move downward, and the first frame moves downward to squeeze the second spring, so that the hook and the locking ring can be tightly clamped, just push and pull the push rod up and down. It can realize the unlocking of the locking ring and the hook, so that it is convenient to open and close, and then it is convenient to take the experimental rats for experimental work, which solves the problem that due to the single functionality of the breeding cage, it is necessary to be equipped with a special experimental operation platform when conducting experiments, which increases the The cost of the experiment is not conducive to the progress of the experiment, and the effect of the fixation method of the limbs is poor, which affects the progress of the experiment and brings inconvenience to the experimenters.
附图说明Description of drawings
图1为本发明主视结构示意图;Fig. 1 is a schematic diagram of the main view structure of the present invention;
图2为本发明固定盒和固定板的爆炸结构示意图;Fig. 2 is a schematic diagram of the exploded structure of the fixed box and the fixed plate of the present invention;
图3为本发明实验箱本体的剖视结构示意图;Fig. 3 is the sectional structure schematic diagram of experiment box body of the present invention;
图4为本发明锁紧单元的主视结构示意图;Fig. 4 is a front structural schematic diagram of the locking unit of the present invention;
图5为本发明图3中A处的局部放大结构示意图。FIG. 5 is a schematic diagram of a partially enlarged structure at A in FIG. 3 of the present invention.
图中:1、实验箱本体;2、固定盒;3、固定板;4、第一夹板;5、第二夹板;6、第一弹簧;7、气缸;8、挡板;9、密封门;10、锁紧单元;101、固定块;102、推杆;103、第一框架;104、支撑板;105、连接杆;106、锁止环;107、挂钩;108、第二弹簧;109、第一限位槽;1010、第一限位块;11、密封板;12、第一魔术贴;13、第二魔术贴;14、第一滑槽;15、第一滑块;16、第二限位槽;17、第二限位块;18、第二框架;19、网片;20、第二滑槽;21、第二滑块;22、收集盒;23、第三滑槽;24、第三滑块;25、观察孔;26、换气扇;27、紫外线杀菌灯。In the figure: 1. Experimental box body; 2. Fixed box; 3. Fixed plate; 4. First splint; 5. Second splint; 6. First spring; 7. Cylinder; 8. Baffle; 9. Sealed
具体实施方式Detailed ways
下面将结合本发明实施例中的附图,对本发明实施例中的技术方案进行清楚、完整地描述,显然,所描述的实施例仅仅是本发明一部分实施例,而不是全部的实施例。基于本发明中的实施例,本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例,都属于本发明保护的范围。The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.
本发明的实验箱本体1、固定盒2、固定板3、第一夹板4、第二夹板5、第一弹簧6、气缸7、挡板8、密封门9、锁紧单元10、固定块101、推杆102、第一框架103、支撑板104、连接杆105、锁止环106、挂钩107、第二弹簧108、第一限位槽109、第一限位块1010、密封板11、第一魔术贴12、第二魔术贴13、第一滑槽14、第一滑块15、第二限位槽16、第二限位块17、第二框架18、网片19、第二滑槽20、第二滑块21、收集盒22、第三滑槽23、第三滑块24、观察孔25、换气扇26和紫外线杀菌灯27部件均为通用标准件或本领域技术人员知晓的部件,其结构和原理都为本技术人员均可通过技术手册得知或通过常规实验方法获知。
请参阅图1-5,一种动物毒理实验用实验箱,包括实验箱本体1,实验箱本体1的顶部固定连接有固定盒2,固定盒2的前端固定连接有固定板3,固定板3内腔的上端活动连接有第一夹板4,第一夹板4的内腔设置有第二夹板5,第二夹板5的顶部固定连接有第一弹簧6,第一弹簧6远离第二夹板5的一端与第一夹板4的内壁固定连接,固定板3的顶部固定连接有气缸7,气缸7的输出端贯穿至固定板3的内腔并与第一夹板4固定连接,固定盒2内腔的后端活动连接有挡板8,实验箱本体1的正面通过铰链铰接有密封门9,密封门9正面上端的两侧均固定连接有锁紧单元10,锁紧单元10包括固定块101,固定块101的正面通过转轴活动连接有推杆102,推杆102表面的上端通过轴承活动连接有第一框架103,第一框架103的内腔活动连接有支撑板104,支撑板104的顶部固定连接有连接杆105,连接杆105远离支撑板104的一端贯穿至第一框架103的外部并固定连接有锁止环106,实验箱本体1正面上端的两侧均固定连接有挂钩107,挂钩107延伸至锁止环106的内腔并与锁止环106的内腔活动连接,连接杆105位于第一框架103内腔的一端套设有第二弹簧108,第二弹簧108的两端分别与第一框架103和支撑板104固定连接,通过设置实验箱本体1,起到了能够对实验大鼠进行饲养观察的效果,通过设置固定盒2、固定板3、第一夹板4、第二夹板5、第一弹簧6、气缸7和挡板8,起到了能够对实验大鼠注射时进行固定的效果,气缸7向下运动带动第一夹板4向下运动,第一夹板4向下运动带动第二夹板5向下运动,第一夹板4、第二夹板5和固定板3配合能够对实验大鼠的头颈部进行固定,从而防止实验大鼠在注射时受到惊吓发生反抗行为,影响实验进展,通过设置密封门9,用于对实验箱本体1进行密封,防止实验大鼠从实验箱本体1的内腔跑出,通过固定块101、推杆102、第一框架103、支撑板104、连接杆105、锁止环106、挂钩107和第二弹簧108的配合,起到了能够对实验箱本体1和密封门9固定,锁止环106与挂钩107卡接,推杆102向下运动带动第一框架103向下运动,第一框架103向下运动对第二弹簧108进行挤压,从而能够使挂钩107和锁止环106紧密卡接,只需上下推拉推杆102就能够实现对锁止环106和挂钩107的解锁,从而方便开合,进而方便拿取实验大鼠进行实验工作,解决了由于饲养笼功能性较为单一,进行实验时还需要专门配备实验操作平台,增加了实验成本还不利于实验进展,而且肢体的固定方式效果较差,从而影响实验的进展,给实验人员带来了不便的问题。Please refer to Fig. 1-5, a kind of experiment box for animal toxicology experiment, comprises experiment box body 1, and the top of experiment box body 1 is fixedly connected with fixed box 2, and the front end of fixed box 2 is fixedly connected with fixed plate 3, fixed plate 3 The upper end of the inner cavity is movably connected with a first splint 4, and the inner cavity of the first splint 4 is provided with a second splint 5, and the top of the second splint 5 is fixedly connected with a first spring 6, and the first spring 6 is far away from the second splint 5 One end is fixedly connected with the inner wall of the first splint 4, the top of the fixed plate 3 is fixedly connected with the cylinder 7, the output end of the cylinder 7 penetrates the inner cavity of the fixed plate 3 and is fixedly connected with the first splint 4, and the inner cavity of the fixed box 2 The rear end of the test box body 1 is movably connected with a baffle plate 8, and the front of the test box body 1 is hinged with a sealed door 9, and both sides of the upper end of the sealed door 9 are fixedly connected with a locking unit 10, and the locking unit 10 includes a fixed block 101, The front of the fixed block 101 is movably connected with a push rod 102 through a rotating shaft, and the upper end of the push rod 102 surface is movably connected with a first frame 103 through a bearing, and the inner cavity of the first frame 103 is movably connected with a support plate 104, and the top of the support plate 104 is fixed A connecting rod 105 is connected, and the end of the connecting rod 105 away from the support plate 104 penetrates to the outside of the first frame 103 and is fixedly connected with a locking ring 106. Both sides of the upper end of the front of the
具体的,第一框架103内腔的两侧均开设有第一限位槽109,第一限位槽109的内腔滑动连接有第一限位块1010,第一限位块1010远离第一限位槽109内腔的一端与支撑板104固定连接,通过设置第一限位槽109和固定块101,起到了能够对支撑板104的运动轨迹进行限位的效果,从而能够防止支撑板104在运动时位置发生偏移。Specifically, both sides of the inner cavity of the
具体的,固定盒2的顶部通过铰链铰接有密封板11,密封板11的顶部开设有透气孔,通过设置密封板11,起到了能够对实验大鼠的身体进行固定的效果,从而防止实验大鼠在注射时受到惊吓发生反抗行为,影响实验进展。Specifically, the top of the fixed
具体的,密封板11表面的左侧固定连接有第一魔术贴12,固定盒2左侧的上端固定连接有第二魔术贴13,第一魔术贴12远离第二魔术贴13的一端与第二魔术贴13粘接,通过设置第一魔术贴12和第二魔术贴13,用于将密封板11与固定盒2固定,防止实验大鼠反抗时使密封板11与固定盒2脱离发生挣脱的情况。Specifically, the left side of the surface of the sealing
具体的,固定盒2内腔后端的两侧均开设有第一滑槽14,第一滑槽14的内腔滑动连接有第一滑块15,第一滑块15远离第一滑槽14内腔的一端与挡板8固定连接,通过设置第一滑槽14和第一滑块15,起到了能够方便抽拉挡板8的效果,进而能够方便调节挡板8的位置。Specifically, both sides of the rear end of the inner cavity of the fixed
具体的,固定板3内腔的两侧均开设有第二限位槽16,第二限位槽16的内腔滑动连接有第二限位块17,第二限位块17远离第二限位槽16内腔的一端与第一夹板4固定连接,通过设置第二限位槽16和第二限位块17,起到了能够对第一夹板4的运动轨迹进行限位的效果,防止第一夹板4在运动时位置发生偏移。Specifically, both sides of the inner cavity of the fixed
具体的,实验箱本体1内腔的上端活动连接有第二框架18,第二框架18的内腔固定连接有网片19,实验箱本体1内腔上端的两侧均开设有第二滑槽20,第二滑槽20的内腔滑动连接有第二滑块21,第二滑块21远离第二滑槽20内腔的一端与第二框架18固定连接,通过设置第二框架18和网片19,用于放置实验大鼠,通过设置第二滑槽20和第二滑块21,起到了能够方便将第二框架18抽出的效果,进而能够方便对网片19进行清理。Specifically, the upper end of the inner cavity of the
具体的,实验箱本体1内腔的下端活动连接有收集盒22,实验箱本体1内腔下端的两侧均开设有第三滑槽23,第三滑槽23的内腔滑动连接有第三滑块24,第三滑块24远离第三滑槽23内腔的一端与收集盒22固定连接,通过设置收集盒22,起到了能够收集实验大鼠粪便的效果,从而能够保证实验大鼠饲养的舒适环境,通过设置第三滑槽23和第三滑块24,起到了能够方便将收集盒22取出的效果,从而能够方便对收集盒22进行清理。Specifically, the lower end of the inner cavity of the
具体的,实验箱本体1的两侧均开设有观察孔25,观察孔25的内腔固定连接有透明玻璃,实验箱本体1内腔的背面固定连接有换气扇26,实验箱本体1内腔的右侧固定连接有紫外线杀菌灯27,通过设置观察孔25,能够方便观察实验大鼠注射后实验情况,通过设置换气扇26,用于使实验箱本体1内腔的空气流通,通过设置紫外线杀菌灯27,用于对实验箱本体1的内腔进行消毒作业。Specifically, both sides of the
具体的,其使用方法包括如下步骤:Specifically, its use method includes the following steps:
A.首先将实验大鼠放置在固定盒2的内腔,将实验大鼠头颈部放置在固定板3的内腔,通过外设控制器启动气缸7,气缸7的输出轴向下运动带动第一夹板4和第二夹板5通过第二限位块17沿着第二限位槽16的内腔向下运动,第一夹板4与固定板3卡合并对实验大鼠头颈部进行固定,接着将挡板8通过第一滑块15和第一滑槽14安装在实验大鼠尾部,将密封板11盖合在固定盒2的顶部,拉动第一魔术贴12与第二魔术贴13粘接,使其对实验大鼠身体进行固定,对实验大鼠用药完成后,反之上述步骤将实验大鼠取出,放置在实验箱本体1的内腔进行观察;A. First place the experimental rat in the inner cavity of the fixed
B.将实验大鼠放置在实验箱本体1内腔网片19的顶部后,向上拉动密封门9,使密封门9对实验箱本体1进行密封,然后向上推动拉动推杆102,推杆102带动第一框架103向上运动,第一框架103推动锁止环106向上运动,使锁止环106与挂钩107卡合,然后向下按压推杆102,推杆102带动第一框架103向下运动,第一框架103向下运动时对连接杆105造成挤压,使连接杆105发生形变,从而使锁止环106与挂钩107紧密卡接,使密封门9和实验箱本体1进行固定;B. After the experimental rat is placed on the top of the
C.通过外设控制器启动换气扇26和紫外线杀菌灯27,换气扇26旋转产生的气流将实验箱本体1内腔的异味排出,紫外线杀菌灯27对实验箱本体1的内腔进行消毒杀菌作业,实验大鼠的粪便通过网片19落入收集盒22的内腔,将收集盒22通过第三滑槽23和第三滑块24可从实验箱本体1的内腔抽出对收集盒22进行清洗,向外拉动第二框架18,第二框架18通过第二滑块21和第二滑槽20的配合,可从实验箱本体1的内腔取出对网片19进行清洗。C. Start the ventilating
使用时,首先将实验大鼠放置在固定盒2的内腔,将实验大鼠头颈部放置在固定板3的内腔,通过外设控制器启动气缸7,气缸7的输出轴向下运动带动第一夹板4和第二夹板5通过第二限位块17沿着第二限位槽16的内腔向下运动,第一夹板4与固定板3卡合并对实验大鼠头颈部进行固定,接着将挡板8通过第一滑块15和第一滑槽14安装在实验大鼠尾部,将密封板11盖合在固定盒2的顶部,拉动第一魔术贴12与第二魔术贴13粘接,使其对实验大鼠身体进行固定,对实验大鼠用药完成后,反之上述步骤将实验大鼠取出,放置在实验箱本体1的内腔进行观察,将实验大鼠放置在实验箱本体1内腔网片19的顶部后,向上拉动密封门9,使密封门9对实验箱本体1进行密封,然后向上推动拉动推杆102,推杆102带动第一框架103向上运动,第一框架103推动锁止环106向上运动,使锁止环106与挂钩107卡合,然后向下按压推杆102,推杆102带动第一框架103向下运动,第一框架103向下运动时对连接杆105造成挤压,使连接杆105发生形变,从而使锁止环106与挂钩107紧密卡接,使密封门9和实验箱本体1进行固定,通过外设控制器启动换气扇26和紫外线杀菌灯27,换气扇26旋转产生的气流将实验箱本体1内腔的异味排出,紫外线杀菌灯27对实验箱本体1的内腔进行消毒杀菌作业,实验大鼠的粪便通过网片19落入收集盒22的内腔,将收集盒22通过第三滑槽23和第三滑块24可从实验箱本体1的内腔抽出对收集盒22进行清洗,向外拉动第二框架18,第二框架18通过第二滑块21和第二滑槽20的配合,可从实验箱本体1的内腔取出对网片19进行清洗,以此解决了由于饲养笼功能性较为单一,进行实验时还需要专门配备实验操作平台,增加了实验成本还不利于实验进展,而且肢体的固定方式效果较差,从而影响实验的进展,给实验人员带来了不便的问题。When in use, first place the experimental rat in the inner cavity of the fixed
本申请文件中使用到的标准零件均可以从市场上购买,而且根据说明书和附图的记载均可以进行订制,各个零件的具体连接方式均采用现有技术中成熟的螺栓、铆钉、焊接等常规手段,机械、零件和设备均采用现有技术中常规的型号,控制方式是通过控制器来自动控制,控制器的控制电路通过本领域的技术人员简单编程即可实现,属于本领域的公知常识,并且本申请文主要用来保护机械装置,所以本申请文不再详细解释控制方式和电路连接。The standard parts used in this application document can be purchased from the market, and can be customized according to the instructions and drawings. The specific connection methods of each part adopt mature bolts, rivets, welding, etc. in the prior art. Conventional means, machinery, parts and equipment all adopt conventional models in the prior art, and the control mode is automatically controlled by a controller. The control circuit of the controller can be realized by simple programming by those skilled in the art, and belongs to the well-known knowledge in the art. Common sense, and this application is mainly used to protect mechanical devices, so this application will not explain the control method and circuit connection in detail.
需要说明的是,在本文中,诸如第一和第二等之类的关系术语仅仅用来将一个实体或者操作与另一个实体或操作区分开来,而不一定要求或者暗示这些实体或操作之间存在任何这种实际的关系或者顺序。而且,术语“包括”、“包含”或者其任何其他变体意在涵盖非排他性的包含,从而使得包括一系列要素的过程、方法、物品或者设备不仅包括那些要素,而且还包括没有明确列出的其他要素,或者是还包括为这种过程、方法、物品或者设备所固有的要素。在没有更多限制的情况下,由语句“包括一个……”限定的要素,并不排除在包括所述要素的过程、方法、物品或者设备中还存在另外的相同要素。It should be noted that in this article, relational terms such as first and second are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply that there is a relationship between these entities or operations. There is no such actual relationship or order between them. Furthermore, the term "comprises", "comprises" or any other variation thereof is intended to cover a non-exclusive inclusion such that a process, method, article, or apparatus comprising a set of elements includes not only those elements, but also includes elements not expressly listed. other elements of or also include elements inherent in such a process, method, article, or device. Without further limitations, an element defined by the phrase "comprising a ..." does not exclude the presence of additional identical elements in the process, method, article or apparatus comprising said element.
尽管已经示出和描述了本发明的实施例,对于本领域的普通技术人员而言,可以理解在不脱离本发明的原理和精神的情况下可以对这些实施例进行多种变化、修改、替换和变型,本发明的范围由所附权利要求及其等同物限定。Although the embodiments of the present invention have been shown and described, those skilled in the art can understand that various changes, modifications and substitutions can be made to these embodiments without departing from the principle and spirit of the present invention. and modifications, the scope of the invention is defined by the appended claims and their equivalents.
Claims (10)
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