CN111381055A - Calibration data display method and sample analysis device - Google Patents
Calibration data display method and sample analysis device Download PDFInfo
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- CN111381055A CN111381055A CN201811642296.1A CN201811642296A CN111381055A CN 111381055 A CN111381055 A CN 111381055A CN 201811642296 A CN201811642296 A CN 201811642296A CN 111381055 A CN111381055 A CN 111381055A
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- 238000000034 method Methods 0.000 title claims abstract description 44
- 238000004458 analytical method Methods 0.000 title claims description 29
- 238000006243 chemical reaction Methods 0.000 claims abstract description 167
- 238000012360 testing method Methods 0.000 claims abstract description 119
- 230000004044 response Effects 0.000 claims description 53
- 239000003153 chemical reaction reagent Substances 0.000 claims description 31
- 239000003086 colorant Substances 0.000 claims description 10
- 238000011088 calibration curve Methods 0.000 description 26
- 238000003908 quality control method Methods 0.000 description 23
- 238000002835 absorbance Methods 0.000 description 16
- 230000008859 change Effects 0.000 description 9
- 238000010586 diagram Methods 0.000 description 6
- 230000006870 function Effects 0.000 description 6
- 230000003287 optical effect Effects 0.000 description 4
- 238000004590 computer program Methods 0.000 description 3
- 239000000463 material Substances 0.000 description 2
- 230000008569 process Effects 0.000 description 2
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- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000003018 immunoassay Methods 0.000 description 1
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00594—Quality control, including calibration or testing of components of the analyser
Abstract
A calibration data display method and a sample analyzer, comprising determining a calibration product and calibration items thereof; according to the determined calibrator and the calibration items thereof, acquiring reaction data of the calibrator about N times of calibration tests of the calibration items; wherein N is a natural number not less than 2; and displaying the reaction data of the N times of calibration tests on the same calibration data interface. The invention simultaneously displays the reaction data of repeated calibration tests on the same interface, so that a user can judge the repeatability and stability of the calibration data by comparing the reaction data of repeated calibration tests on the same interface, and the method is very convenient.
Description
Technical Field
The present invention relates to a calibration data display method and a sample analyzer.
Background
A sample analyzer is a device for measuring a chemical composition or a physical property of a sample. For example, in a biochemical analyzer, an immunoassay analyzer, or the like, a reagent is generally added to a sample, and a chemical component, concentration, or the like in the sample is measured optically or the like with respect to the sample after reaction with the reagent. It can be seen that, taking the example of measuring the concentration of the sample, the physical quantity of the sample after the reaction with the reagent, which is directly obtained by the sample analyzer, is not the concentration, for example, the physical quantity directly obtained is an optical quantity, so in order to convert the physical quantity (for example, the optical quantity) of the sample after the reaction, which is directly obtained by the sample analyzer, into the physical quantity (for example, the concentration) to be tested, a calibration test needs to be performed by the calibrator to obtain the conversion relationship therebetween.
In general, the calibration product is a standardized sample with a known concentration, and the reaction data of the calibration test is obtained by reacting the calibration product with a reagent, and the reaction data is generally presented in the form of a curve, and therefore may be generally referred to as a calibration curve, and the above-mentioned conversion relationship may be finally obtained by the concentration of the calibration product itself and the calibration curve. It can be seen that the calibration curve has a direct and important effect on the test results; therefore, the same calibrator is usually subjected to multiple calibration tests repeatedly to check the repeatability and stability of the calibration curve.
In addition to calibration curves, control curves and reaction curves of the sample itself are involved in the sample testing process. The reaction curve of the sample refers to a data curve obtained by the sample analysis device measuring the sample to be tested after reacting with the reagent. The quality control curve is a data curve obtained by the reaction of the quality control product and the reagent and is used for detecting whether the stability of the sample analysis device meets the requirement.
For the same test item of the same sample, generally only one test is needed; similarly, only one test is generally needed for the same quality control item of the same quality control product; however, the same calibration item of the same calibrator is usually tested repeatedly. In the prior art, when a reaction curve of a sample is displayed on a relevant interface, a corresponding reaction curve is displayed by selecting the sample and a test item; the method is similar when the quality control curve is displayed on the quality control related interface, namely a corresponding quality control curve is displayed by selecting a quality control product and a quality control item; the display of calibration curves on the calibration-related interface is similar, except that since the calibration sample may be repeatedly tested, a corresponding calibration curve is displayed by selecting a sample, calibration items, and calibration time points (each corresponding to a calibration test).
Disclosure of Invention
The above-mentioned method for displaying the reaction curve, the quality control curve and the calibration curve of the sample does not take into account the difference between the three and the actual user requirements, so the present application provides a method for displaying calibration data and a sample analyzer.
According to a first aspect, there is provided in an embodiment a calibration data display method comprising:
determining a calibration product and calibration items thereof;
according to the determined calibrator and the calibration items thereof, acquiring reaction data of the calibrator about N times of calibration tests of the calibration items; wherein N is a natural number not less than 2;
and displaying the reaction data of the N times of calibration tests on the same calibration data interface.
In one embodiment, in response to a user instruction to display all of the curves, the reaction data of the calibrator with respect to the N calibration tests of the calibration item is displayed on the same calibration data interface.
In one embodiment, the calibration data interface includes an all-curve control for receiving the instruction to display all curves.
In an embodiment, the all-curve control is a check box, and when the check box is checked, it indicates that the instruction for showing all the curves is received, and otherwise, it indicates that the instruction for showing all the curves is not received.
In one embodiment, the calibration data display method further includes:
determining calibration time points, wherein each calibration time point corresponds to one calibration test;
according to the determined calibrator, the calibration items and the calibration time points of the calibrator, acquiring reaction data of the calibrator about a single calibration test corresponding to the calibration items at the calibration time points;
when the instruction showing all the curves is not received, only the reaction data of the calibrator about the single calibration test corresponding to the calibration item at the calibration time point is displayed on the calibration data interface.
In one embodiment, the calibration data interface includes a curvilinear display area and/or a digital display area; the curve display area displays reaction data in a coordinate drawing point mode; the digital display area displays the reaction data in a digital list mode.
In one embodiment, parameters needing to be displayed in the reaction data are determined in response to a parameter selection instruction of the reaction data; and displaying parameters required to be displayed in the reaction data in a calibration data interface.
In one embodiment, the calibration data display method further includes:
capturing the cursor position of the curve display area;
when the cursor position is judged to be located in a preset range of the point drawn in the curve display area, the coordinate value of the point is displayed nearby in a numerical value mode.
In one embodiment, the calibration data interface includes a plurality of check boxes, each check box corresponding to a parameter in the reaction data; and checking any check box to show that a corresponding parameter selection instruction in the reaction data is received and the parameter corresponding to the check box needs to be displayed in the reaction data is determined.
In one embodiment, the check boxes include a check box corresponding to the primary wavelength in the response data, a check box corresponding to the secondary wavelength in the response data, and a check box corresponding to the primary wavelength minus the secondary wavelength in the response data.
In one embodiment, different parameters to be displayed in the reaction data are displayed in different colors in the calibration data interface.
In one embodiment, the calibration data interface further includes a curve adjustment control for receiving a curve adjustment instruction;
in response to the curve adjustment instruction, adjusting a vertical coordinate proportion of coordinates in the curve display area such that different displayed reaction data or different parameters of the same reaction data do not visually coincide together.
In one embodiment, the calibration data display method further includes: and judging the stability of the calibration product when the calibration item is carried out according to the reaction data of the calibration product about the N times of calibration tests of the calibration item, and prompting a reason and/or giving an alarm when the stability is judged to be poor.
According to a second aspect, there is provided in an embodiment a sample analysis device comprising: a sample component, a reagent component, an analysis component, a controller, and a display;
the sample part is used for bearing a sample to be tested, sucking the sample and then providing the sample to the analysis part;
the reagent part is used for bearing a reagent, and the reagent is sucked and then provided for the analysis part;
the analysis component is used for acquiring and analyzing reaction data of the sample and the reagent to obtain a test result;
the controller is used for determining a calibration product and calibration items thereof; according to the determined calibration product and the calibration items thereof, acquiring reaction data of the calibration product about N times of calibration tests of the calibration items, wherein N is a natural number not less than 2;
and the display is used for displaying the reaction data of the N times of calibration tests on the same calibration data interface.
In one embodiment, the controller controls the display to display the reaction data of the calibrator with respect to the N calibration tests of the calibration item on the same calibration data interface in response to an instruction from the user to display all the curves.
In one embodiment, the calibration data interface includes all curve controls, and the controller receives the instruction for displaying all curves through all the curve controls.
In an embodiment, the all-curve control is a check box, and when the check box is checked, it indicates that the controller receives the instruction for showing all the curves, and otherwise, it indicates that the controller does not receive the instruction for showing all the curves.
In one embodiment, the controller is further configured to determine calibration time points, wherein each calibration time point corresponds to a calibration test; according to the determined calibrator, the calibration items and the calibration time points of the calibrator, acquiring reaction data of the calibrator about a single calibration test corresponding to the calibration items at the calibration time points; when the instruction for displaying all the curves is not received, controlling a display to display only the reaction data of the calibrator about the single calibration test corresponding to the calibration item at the calibration time point on the calibration data interface.
In one embodiment, the calibration data interface includes a curvilinear display area and/or a digital display area; the curve display area displays reaction data in a coordinate drawing point mode; the digital display area displays the reaction data in a digital list mode.
In one embodiment, the controller further responds to a parameter selection instruction of the reaction data, and determines parameters needing to be displayed in the reaction data; and the controller controls the display to display parameters required to be displayed in the reaction data on the calibration data interface.
In one embodiment, the controller further captures a cursor position of the curve display area, and controls the display to display the coordinate value of the point in the vicinity of the point in a numerical value form when the cursor position is determined to be within a preset range of the point drawn in the curve display area.
In one embodiment, the calibration data interface includes a plurality of check boxes, each check box corresponding to a parameter in the reaction data; and any check box is checked to show that the controller receives a selection instruction of the corresponding parameter in the reaction data and determines that the parameter corresponding to the check box needs to be displayed in the reaction data.
In one embodiment, the check boxes include a check box corresponding to the primary wavelength in the response data, a check box corresponding to the secondary wavelength in the response data, and a check box corresponding to the primary wavelength minus the secondary wavelength in the response data.
In one embodiment, the display displays different parameters to be displayed in the reaction data in different colors in the calibration data interface.
In one embodiment, the calibration data interface further includes a curve adjustment control, and the controller receives a curve adjustment instruction through the curve adjustment control;
the controller is responsive to the curve adjustment instructions to adjust the ordinate scale of the coordinates in the curve display area such that different response data or different parameters of the same response data displayed by the display do not visually coincide together.
In one embodiment, the controller determines the stability of the calibration item of the calibration product according to the reaction data of the calibration product about the N times of calibration tests of the calibration item, and prompts a reason and/or gives an alarm when determining that the stability is poor.
According to a third aspect, an embodiment provides a computer readable storage medium comprising a program executable by a processor to implement a method as described in any of the embodiments herein.
A calibration data display method, a sample analysis device, and a computer-readable storage medium, including determining a calibration product and calibration items thereof; according to the determined calibrator and the calibration items thereof, acquiring reaction data of the calibrator about N times of calibration tests of the calibration items; wherein N is a natural number not less than 2; the reaction data of the N times of calibration tests are displayed on the same calibration data interface, so that the reaction data of the repeated calibration tests are simultaneously displayed on the same interface, and a user can judge the repeatability and stability of the calibration data by comparing the reaction data of the repeated calibration tests on the same interface, and the method is very convenient.
Drawings
FIG. 1 is a schematic view of an embodiment of a calibration correlation interface;
FIG. 2 is a schematic structural diagram of a sample analyzer according to an embodiment;
FIG. 3 is two schematic diagrams of a calibration data interface including all curve controls according to one embodiment;
FIG. 4 is two schematic diagrams of a calibration data interface including a curvilinear display area and a digital display area according to an embodiment;
FIG. 5 is a state diagram of a calibration data interface of an embodiment;
FIG. 6 is a schematic diagram of a calibration data interface including a curve adjustment control, according to an embodiment;
FIG. 7 is a diagram illustrating an embodiment of a calibration data interface displaying only data associated with a dominant wavelength in a digital display region;
FIG. 8 is a flow chart of a calibration data display method according to an embodiment;
FIG. 9 is a flowchart of a calibration data display method according to another embodiment.
Detailed Description
The present invention will be described in further detail with reference to the following detailed description and accompanying drawings. Wherein like elements in different embodiments are numbered with like associated elements. In the following description, numerous details are set forth in order to provide a better understanding of the present application. However, those skilled in the art will readily recognize that some of the features may be omitted or replaced with other elements, materials, methods in different instances. In some instances, certain operations related to the present application have not been shown or described in detail in order to avoid obscuring the core of the present application from excessive description, and it is not necessary for those skilled in the art to describe these operations in detail, so that they may be fully understood from the description in the specification and the general knowledge in the art.
Furthermore, the features, operations, or characteristics described in the specification may be combined in any suitable manner to form various embodiments. Also, the various steps or actions in the method descriptions may be transposed or transposed in order, as will be apparent to one of ordinary skill in the art. Thus, the various sequences in the specification and drawings are for the purpose of describing certain embodiments only and are not intended to imply a required sequence unless otherwise indicated where such sequence must be followed.
The numbering of the components as such, e.g., "first", "second", etc., is used herein only to distinguish the objects as described, and does not have any sequential or technical meaning. The term "connected" and "coupled" when used in this application, unless otherwise indicated, includes both direct and indirect connections (couplings).
Considering the amount of the sample and the actual requirement, the same sample is generally only required to be tested once aiming at the same test project, and the stability of the reaction curve of the sample is not required to be tested by multiple repeated tests; similarly, the same quality control product aims at the same quality control project, only one test is needed in consideration of cost and actual requirements, and the stability of a quality control curve is detected without repeated tests. The calibration processes are different, and the same calibration product generally needs to be tested for multiple times (i.e. repeated tests) for the same calibration item to check the stability and repeatability of the calibration curve. In the prior art, the reaction curve, the quality control curve and the calibration curve of the sample are respectively displayed on the sample correlation interface, the quality control correlation interface and the calibration correlation interface, and the difference is not considered, so that when a user wants to check the stability and the repeatability of the calibration yellow line, the user generally selects a calibrator, a calibration item and a calibration time point (namely, a calibration time point, each calibration time point corresponds to a calibration test) on the calibration correlation interface to display one calibration curve, and then checks the corresponding calibration curve by selecting different calibration time points.
For example, the calibrator a repeats 3 tests for the calibration item Test1 to obtain 3 calibration curves, where the time points of the 3 calibration tests are t1, t2, and t3, respectively, in order to check the 3 calibration curves, a user needs to select the calibrator a and the calibration item Test1 at a calibration related interface first, then select the calibration time point as t1, a calibration curve corresponding to t1 appears, then modify the selected calibration time point from t1 to t2, the calibration curve corresponding to t1 disappears, the calibration curve corresponding to t2 appears on the interface, then modify the selected calibration time point from t2 to t3, the calibration curve corresponding to t2 disappears, the calibration curve corresponding to t3 appears on the interface, and the user can check the three calibration curves by this way, if necessary, take a picture of the three calibration curves with a mobile phone or the like or record the three calibration curves with a pen, the three calibration curves are compared, and the stability and repeatability of the three calibration curves are judged based on experience. Fig. 1 shows an actual calibration-related interface, where an item drop-down box is used to select a calibration item, a calibrator drop-down box is used to select a calibrator, and a calibration time drop-down box is used to select a calibration time point, but some other information, such as the concentration, the location, and the number of repeated tests of the calibrator, may also be displayed on the interface. After the calibrator and calibration items in the calibrator drop-down box and the item drop-down box are respectively determined, the user may select a calibration time point in the calibration time drop-down box to display a corresponding calibration curve on the interface.
In view of the fact that the calibration correlation interface is the same as the sample correlation interface and the quality control correlation interface, and only one test curve can be checked each time, which is not beneficial for a user to evaluate the repeatability and stability of the calibration curve, the inventor proposes a new display method and device, which will be described in detail below.
Referring to fig. 2, an embodiment of the present invention provides a sample analyzer, which includes a sample unit 10, a reagent unit 20, an analysis unit 30, a controller 40, and a display 50.
The sample part 10 is used for carrying a sample to be tested, and the sample is sucked and supplied to the analysis part 30. It will be appreciated that when the sample analysis apparatus is performing a quality control test or calibration test, the sample block 10 carries a quality control or calibration product, since the quality control and calibration product can be considered to be a standardized sample of known concentration.
The reagent unit 20 is used for carrying a reagent, and the reagent is aspirated and supplied to the analysis unit 30.
The analyzing part 30 is used to acquire and analyze reaction data of the sample and the reagent to obtain a test result. It is to be understood that, when the sample analyzer performs a quality control test, the analyzing unit 30 is used to obtain reaction data, or quality control data, of the quality control test of the quality control material and the reagent; similarly, when the sample analysis apparatus performs a calibration test, the analysis component 30 is used to obtain reaction data, or calibration data, of the calibration test of the calibrator and the reagent.
In one embodiment, the controller 40 is configured to determine a calibration product and a calibration item thereof, and obtain response data of the calibration product with respect to N calibration tests of the calibration item according to the determined calibration product and the calibration item thereof, where N is a natural number not less than 2. For example, the controller 40 first determines that the calibrator is calibrator a and its calibration item is calibration item Test1, and then obtains the response data of the calibrator a with respect to the multiple calibration tests of calibration item Test1, for example, the response data of all or at least two of all the calibration tests, in a preferred embodiment, the response data of all the calibration tests, according to the determined calibrator a and its calibration item Test 1. The display 50 is used for displaying the reaction data of the N calibration tests on the same calibration data interface, that is, the display simultaneously displays the reaction data of the N calibration tests on one interface, so that a user can conveniently compare the reaction data of the N calibration tests and judge the repeatability, stability and the like of the reaction data.
In one embodiment, the controller 40 may control the display 50 to display the reaction data of the calibrator with respect to the N calibration tests of the calibration item on the same calibration data interface in response to a user instruction to display all the curves. Referring to fig. 3, for example, in an embodiment, the calibration data interface may include an all-curve control 41, and the controller 40 may receive an instruction for showing all curves through the all-curve control 41. For example, the all-curve control 41 may be a check box, and when the check box is checked, for example, the user clicks the check box by a mouse or the like to change the check box from the unchecked state to the checked state, it indicates that the user inputs an instruction to show all the curves, and accordingly, the controller 40 also receives the instruction to show all the curves; conversely, when the check box is not checked, for example, the user clicks the check box by a mouse or the like to change the check box from the checked state to the unchecked state, it indicates that the user does not input an instruction to show all the curves, and accordingly, the controller 40 does not receive the instruction to show all the curves. Where fig. 3(a) shows a state where the check boxes of all the curve controls 41 are not checked, and fig. 3(b) shows a state where the check boxes of all the curve controls 41 are checked, and a response curve of 3 calibration tests is displayed, where N is 3. In a typical scenario, when the user clicks the check boxes of all the curve controls 41 to change the check boxes from the unchecked state to the checked state, the controller 40 controls the display 50 to simultaneously display the response data of the N calibration tests on the calibration data interface.
The above are some illustrations of the controller 40 controlling the display 50 to simultaneously present the reaction data of the same calibrator on multiple calibration tests of the same calibration item at the same interface. In some embodiments, the controller 40 may also control the display 50 to display the response data of the calibration test only once. For example, in one embodiment, the controller 40 is further configured to determine calibration time points, where each calibration time point corresponds to one calibration test, i.e., the calibration item, and the calibration time point can determine their corresponding one calibration test. The controller 40 acquires reaction data of the calibrator about a single calibration test corresponding to the calibration item at the calibration time point according to the determined calibrator, the calibration item and the calibration time point; when the instruction to show all the curves is not received, the controller 40 controls the display 50 to display only the reaction data of the calibration product on the calibration data interface with respect to the single calibration test corresponding to the calibration item at the calibration time point. For example, fig. 3(a) is an example of the controller 40 also controlling the display 50 to display the response data of the calibration test only once, wherein the user can select the calibration time point through the calibration time drop-down box, and the controller 40 determines the calibration time point according to the calibration time point selected by the user in the calibration time drop-down box. In a typical scenario, when the user clicks the check boxes of all the curve controls 41 to change from the unchecked state to the checked state, the controller 40 controls the display 50 to simultaneously display the reaction data of the N calibration tests on the calibration data interface; when the user clicks the check boxes of all the curve controls 41 to change the check boxes from being checked to the unchecked state, the controller 40 controls the display 50 to display the reaction data of only one calibration test corresponding to the determined calibration time point on the calibration data interface.
The manner in which the display 50 displays the response data of the calibration test is described below.
The calibration data interface displayed by the display 50 in one embodiment may include a curvilinear display region and/or a numeric display region. For example, the curve display area and the digital display area can be switched in the calibration data interface in a tab mode, or the curve display area and the digital display area can be simultaneously displayed in the calibration data interface for switching, for example, the curve display area is positioned in the upper half part of the calibration data interface, and the digital display area is positioned in the lower half part of the calibration data interface. Fig. 4 shows an example of switching the curve display area and the number display area in the calibration data interface in the form of tabs, where fig. 4(a) shows that the curve display area is selected for display and fig. 4(b) shows that the number display area is selected for display.
In one embodiment, the curve display area displays the response data in a coordinate plot manner. For example, after a reagent is added to a calibration sample for a calibration item to be performed, the analyzing unit 30 measures absorbance of the calibration sample reacted with the reagent, and then reaction data of a calibration test is plotted with a lighting period as abscissa and absorbance as ordinate.
In some embodiments, the reaction data includes a plurality of parameters, such as absorbance for the parameter primary wavelength, absorbance for the parameter secondary wavelength, and absorbance for the parameter primary wavelength minus the parameter secondary wavelength. Therefore, in one embodiment, the controller 40 is further responsive to a parameter selection command for the reaction data to determine the parameters to be displayed in the reaction data; the controller 40 then controls the display 50 to display the parameters to be displayed in the response data in the calibration data interface, such as the curve display area. In order to make the user visually recognize the specific value of each point on the curve display area where the response data is plotted, the controller 40 in one embodiment captures the cursor position of the curve display area, and when the cursor position is determined to be within a predetermined range of the plotted point in the curve display area, controls the display 50 to display the coordinate value of the point in the form of a numerical value in the vicinity of the point. In one embodiment, the calibration data interface may include a plurality of check boxes, each check box corresponding to a parameter in the reaction data, and any check box is checked to indicate that the controller 40 receives a selection instruction for the corresponding parameter in the reaction data and determines that the parameter corresponding to the check box needs to be displayed in the reaction data. For example, the check boxes can include a check box corresponding to the primary wavelength in the reaction data, a check box corresponding to the secondary wavelength in the reaction data, and a check box corresponding to the primary wavelength minus the secondary wavelength in the reaction data. In order to allow the user to visually distinguish between the various parameters in the displayed reaction data in the curve display area, the display 50 in one embodiment displays the different parameters that need to be displayed in the reaction data in different colors in the calibration data interface. For example, the plot plotted in the plot area for the point of the dominant wavelength in the reaction data is shown in blue, the point of the secondary wavelength in red, and the point of the dominant wavelength minus the secondary wavelength in yellow; for another example, when the cursor is close to a point, the displayed coordinate values are also displayed in different colors, the coordinate values of the main wavelength in the reaction data are displayed in blue, the coordinate values of the sub-wavelength are displayed in red, and the coordinate values of the main wavelength minus the sub-wavelength are displayed in yellow. For example, referring to fig. 5, the curve display area shows the reaction data of 3 times of repeated calibration tests, and the parameters to be displayed in the reaction data of any one time of calibration test are the main wavelength, the sub-wavelength and the main wavelength minus the sub-wavelength, and since fig. 5 is a black and white line graph, those skilled in the art can understand that the plotted point in the graph and the coordinate value displayed when the cursor is close to the point can be displayed with different colors according to the above manner.
Sometimes, the response data of different calibration tests displayed in the curve display area are overlapped in a staggered manner, which affects the user's view, for example, the response data of different calibration tests in fig. 4(a) and fig. 5 are overlapped at each point when displayed. Referring to fig. 6, in an embodiment, the calibration data interface further includes a curve adjustment control 42, and the controller 40 receives a curve adjustment command through the curve adjustment control 42, for example, the curve adjustment control 42 is a button, and when the button is clicked, the controller 40 receives the curve adjustment command. The controller 40, in response to the curve adjustment instruction, adjusts the ordinate scale of the coordinates in the curve display area so that different response data or different parameters of the same response data displayed by the display 50 do not visually coincide together. In a specific implementation, after the curve adjustment control 42 is clicked, the controller 40 adjusts the ordinate scale of the coordinates in the curve display area, or generates a pop-up box for the user to input the ordinate scale of the coordinates in the curve display area, and the controller 40 adjusts the ordinate scale of the coordinates in the curve display area according to the ordinate scale input by the user.
In one embodiment, the digital display area displays the response data in a digital list. For example, after a reagent is added to a calibrator for a calibration item to be performed, the analyzer 30 measures the absorbance of the calibrator reacted with the reagent, and displays the reaction data of the calibration test below the corresponding column with the lighting cycle in a row and the absorbance in a row. Similarly, in one embodiment, the controller 40 is further responsive to a parameter selection command for the reaction data to determine the parameters to be displayed in the reaction data; the controller 40 then controls the display to display the parameters to be displayed in the response data in a calibration data interface, such as a digital display area. FIG. 7 shows an example in which only the absorbance of the dominant wavelength in the reaction data is shown.
The above are some illustrations of the display 50 showing the response data of the calibration test. The user can judge the repeatability and stability of the calibration data by comparing the reaction data of repeated calibration tests on the same interface. In an embodiment, the controller 40 may further determine the stability of the calibration product when performing the calibration item according to the reaction data of the calibration product about the N times of calibration tests of the calibration item, and prompt a reason and/or issue an alarm when determining that the stability is poor.
The embodiment of the invention also discloses a calibration data display method. Referring to fig. 8, the calibration data display method of an embodiment includes steps 100 to 120, which are described in detail below.
Step 100: and determining the calibration product and the calibration items thereof.
Step 110: and acquiring reaction data of the calibrator about N times of calibration tests of the calibration item according to the determined calibrator and the calibration item thereof, wherein N is a natural number not less than 2.
For example, step 100 first determines that the calibrator is calibrator A and its calibration item is calibration item Test1, and then step 110 obtains the response data of the calibrator A for a plurality of calibration tests of calibration item Test1, for example, the response data of all or at least two of all the calibration tests, in a preferred embodiment, the response data of all the calibration tests, according to the determined calibrator A and its calibration item Test 1.
Step 120: and displaying the reaction data of the N times of calibration tests on the same calibration data interface. Speaking in a sentence changing manner, step 120 displays the reaction data of the N calibration tests on one interface at the same time, so that the user can conveniently compare the reaction data of the N calibration tests and judge the repeatability, stability and the like of the reaction data. In one embodiment, step 120 is to display the reaction data of the calibration article with respect to the N calibration tests of the calibration item on the same calibration data interface in response to an instruction from the user to display all the curves. In a specific implementation, the calibration data interface includes an all-curve control for receiving the instruction for showing all curves, for example, the all-curve control may be a check box, and when the check box is checked, for example, a user clicks the check box by a mouse or the like to change the check box from an unchecked state to a checked state, it indicates that the user inputs the instruction for showing all curves, and accordingly, step 120 also receives the instruction for showing all curves; on the contrary, when the check box is not checked, for example, the user clicks the check box by a mouse or the like to change the check box from the checked state to the unchecked state, which indicates that the user does not input an instruction for showing all the curves, and accordingly, step 120 does not receive the instruction for showing all the curves.
The above is some descriptions that the calibration data display method displays the reaction data of the same calibration product on multiple calibration tests of the same calibration item at the same time on the same interface, and in some embodiments, the calibration data display method may also display the reaction data of only one calibration test. For example, referring to fig. 9, the calibration data display method in an embodiment may further include steps 200 to 220.
Step 200: calibration time points are determined, wherein each calibration time point corresponds to a calibration test.
Step 210: and acquiring reaction data of the calibrator about a single calibration test corresponding to the calibration item at the calibration time point according to the determined calibrator, the calibration item and the calibration time point. The calibration article and its calibration items determined as described herein may be obtained in step 100.
Step 220: when the instruction showing all the curves is not received, only the reaction data of the calibrator about the single calibration test corresponding to the calibration item at the calibration time point is displayed on the calibration data interface.
A typical scenario is that a user clicks check boxes of all curve controls to change the check boxes from an unchecked state to a checked state, and then the reaction data of the N calibration tests are displayed on a calibration data interface at the same time; when the user clicks the check boxes of all the curve controls to change the check boxes from the checked state to the unchecked state, only the reaction data of one calibration test corresponding to the determined calibration time point is displayed on the calibration data interface.
The following describes a manner in which the calibration data display method displays the reaction data of the calibration test, for example, a manner in which the reaction data of the calibration test is displayed in steps 120 and 220.
In one embodiment, the calibration data interface may include a curvilinear display area and/or a numerical display area. For example, the curve display area and the digital display area can be switched in the calibration data interface in a tab mode, or the curve display area and the digital display area can be simultaneously displayed in the calibration data interface for switching, for example, the curve display area is positioned in the upper half part of the calibration data interface, and the digital display area is positioned in the lower half part of the calibration data interface. Fig. 4 shows an example of switching the curve display area and the number display area in the calibration data interface in the form of tabs, where fig. 4(a) shows that the curve display area is selected for display and fig. 4(b) shows that the number display area is selected for display.
In one embodiment, the curve display area displays the response data in a coordinate plot manner. For example, after a reagent is added to a calibration sample for a calibration item to be performed, the analyzing unit 30 measures absorbance of the calibration sample reacted with the reagent, and then reaction data of a calibration test is plotted with a lighting period as abscissa and absorbance as ordinate.
In some embodiments, the reaction data includes a plurality of parameters, such as absorbance for the parameter primary wavelength, absorbance for the parameter secondary wavelength, and absorbance for the parameter primary wavelength minus the parameter secondary wavelength. Therefore, in one embodiment, step 120 and/or step 220 is also responsive to a parameter selection instruction of the reaction data to determine the parameters required to be displayed in the reaction data; and then displaying the parameters to be displayed in the reaction data on a calibration data interface, such as a curve display area. In order to make the user intuitively see the specific value of each point on the curve display area where the reaction data is plotted, in one embodiment, step 120 and/or step 220 further captures the cursor position of the curve display area, and when the cursor position is determined to be within a preset range of the plotted point in the curve display area, the coordinate value is displayed in the form of a numerical value in the vicinity of the point. In one embodiment, the calibration data interface may include a plurality of check boxes, each check box corresponding to a parameter in the reaction data, and any check box is checked to indicate that step 120 and/or step 220 receives a selection instruction for the corresponding parameter in the reaction data, and determines that the parameter corresponding to the check box needs to be displayed in the reaction data. For example, the check boxes can include a check box corresponding to the primary wavelength in the reaction data, a check box corresponding to the secondary wavelength in the reaction data, and a check box corresponding to the primary wavelength minus the secondary wavelength in the reaction data. In order to enable a user to intuitively distinguish the parameters in the displayed reaction data in the curve display area, in one embodiment, different parameters to be displayed in the reaction data are displayed in different colors in the calibration data interface. For example, the plot plotted in the plot area for the point of the dominant wavelength in the reaction data is shown in blue, the point of the secondary wavelength in red, and the point of the dominant wavelength minus the secondary wavelength in yellow; for another example, when the cursor is close to a point, the displayed coordinate values are also displayed in different colors, the coordinate values of the main wavelength in the reaction data are displayed in blue, the coordinate values of the sub-wavelength are displayed in red, and the coordinate values of the main wavelength minus the sub-wavelength are displayed in yellow. For example, referring back to fig. 5, the curve display area shows the reaction data of 3 times of repeated calibration tests, and the reaction data of any one time of calibration test has the parameters of the main wavelength, the sub-wavelength and the main wavelength minus the sub-wavelength, and since fig. 5 is a black and white line graph, those skilled in the art can understand that the plotted point in the graph and the coordinate value displayed when the cursor is close to the point can be displayed with different colors according to the above-mentioned manner.
Sometimes, the response data of different calibration tests displayed in the curve display area are overlapped and staggered, which affects the user's view, for example, please refer to fig. 4(a) and fig. 5, in which the response data of different calibration tests are overlapped at all points when displayed. Referring back to fig. 6, in an embodiment, the calibration data interface further includes a curve adjustment control 42, and the step 120 receives a curve adjustment instruction through the curve adjustment control 42, for example, the curve adjustment control 42 is a button, and when the button is clicked, the step 120 receives the curve adjustment instruction. Step 120 adjusts the ordinate scale of the coordinates in the curve display area in response to the curve adjustment instruction so that different displayed reaction data or different parameters of the same reaction data do not visually coincide together. In a specific implementation, after the curve adjustment control 42 is clicked, the step 120 adjusts the ordinate ratio of the coordinates in the curve display area, or a pop-up box is generated for the user to input the ordinate ratio of the coordinates in the curve display area, and the step 120 adjusts the ordinate ratio of the coordinates in the curve display area according to the ordinate ratio input by the user.
In one embodiment, the digital display area displays the response data in a digital list. For example, after a reagent is added to a calibrator for a calibration item to be performed, the analyzer 30 measures the absorbance of the calibrator reacted with the reagent, and displays the reaction data of the calibration test below the corresponding column with the lighting cycle in a row and the absorbance in a row. Similarly, in an embodiment, step 120 is further responsive to a parameter selection instruction of the reaction data to determine a parameter to be displayed in the reaction data; the controller 40 then controls the display to display the parameters to be displayed in the response data in a calibration data interface, such as a digital display area. Referring back to FIG. 7, this is an example showing only the absorbance of the dominant wavelength in the reaction data.
The above are some of the illustrations showing the response data of the calibration test. The user can judge the repeatability and stability of the calibration data by comparing the reaction data of repeated calibration tests on the same interface. In an embodiment, the calibration data display method further includes: and judging the stability of the calibration product when the calibration item is carried out according to the reaction data of the calibration product about the N times of calibration tests of the calibration item, and prompting a reason and/or giving an alarm when the stability is judged to be poor.
Those skilled in the art will appreciate that all or part of the functions of the various methods in the above embodiments may be implemented by hardware, or may be implemented by computer programs. When all or part of the functions of the above embodiments are implemented by a computer program, the program may be stored in a computer-readable storage medium, and the storage medium may include: a read only memory, a random access memory, a magnetic disk, an optical disk, a hard disk, etc., and the program is executed by a computer to realize the above functions. For example, the program may be stored in a memory of the device, and when the program in the memory is executed by the processor, all or part of the functions described above may be implemented. In addition, when all or part of the functions in the above embodiments are implemented by a computer program, the program may be stored in a storage medium such as a server, another computer, a magnetic disk, an optical disk, a flash disk, or a removable hard disk, and may be downloaded or copied to a memory of a local device, or may be version-updated in a system of the local device, and when the program in the memory is executed by a processor, all or part of the functions in the above embodiments may be implemented.
The present invention has been described in terms of specific examples, which are provided to aid understanding of the invention and are not intended to be limiting. For a person skilled in the art to which the invention pertains, several simple deductions, modifications or substitutions may be made according to the idea of the invention.
Claims (27)
1. A method of displaying calibration data, comprising:
determining a calibration product and calibration items thereof;
according to the determined calibrator and the calibration items thereof, acquiring reaction data of the calibrator about N times of calibration tests of the calibration items; wherein N is a natural number not less than 2;
and displaying the reaction data of the N times of calibration tests on the same calibration data interface.
2. The method of displaying calibration data according to claim 1, wherein the reaction data of the calibrator with respect to the N calibration tests of the calibration item are displayed on the same calibration data interface in response to an instruction from a user to display all the curves.
3. The method of displaying calibration data according to claim 2, wherein the calibration data interface comprises an all-curve control for receiving the instruction to display all curves.
4. The calibration data display method according to claim 3, wherein the all-curve control is a check box, and when the check box is checked, it indicates that the instruction for showing all the curves is received, and otherwise, it indicates that the instruction for showing all the curves is not received.
5. The calibration data display method of claim 4, further comprising:
determining calibration time points, wherein each calibration time point corresponds to one calibration test;
according to the determined calibrator, the calibration items and the calibration time points of the calibrator, acquiring reaction data of the calibrator about a single calibration test corresponding to the calibration items at the calibration time points;
when the instruction showing all the curves is not received, only the reaction data of the calibrator about the single calibration test corresponding to the calibration item at the calibration time point is displayed on the calibration data interface.
6. The calibration data display method of any one of claims 1 to 5, wherein the calibration data interface comprises a curve display area and/or a number display area; the curve display area displays reaction data in a coordinate drawing point mode; the digital display area displays the reaction data in a digital list mode.
7. The calibration data display method of claim 6,
responding to a parameter selection instruction of the reaction data, and determining parameters needing to be displayed in the reaction data;
and displaying parameters required to be displayed in the reaction data in a calibration data interface.
8. The calibration data display method of claim 7, further comprising:
capturing the cursor position of the curve display area;
when the cursor position is judged to be located in a preset range of the point drawn in the curve display area, the coordinate value of the point is displayed nearby in a numerical value mode.
9. The calibration data display method of claim 7 or 8, wherein the calibration data interface comprises a plurality of check boxes, each check box corresponding to a parameter in the reaction data; and checking any check box to show that a corresponding parameter selection instruction in the reaction data is received and the parameter corresponding to the check box needs to be displayed in the reaction data is determined.
10. The calibration data display method of claim 8, wherein the check boxes comprise a check box corresponding to the primary wavelength in the response data, a check box corresponding to the secondary wavelength in the response data, and a check box corresponding to the primary wavelength minus the secondary wavelength in the response data.
11. The method of claim 7, wherein different parameters to be displayed in the reaction data are displayed in different colors in the calibration data interface.
12. The calibration data display method of claim 1, wherein the calibration data interface further comprises a curve adjustment control for receiving a curve adjustment instruction;
in response to the curve adjustment instruction, adjusting a vertical coordinate proportion of coordinates in the curve display area such that different displayed reaction data or different parameters of the same reaction data do not visually coincide together.
13. The calibration data display method of claim 1, further comprising: and judging the stability of the calibration product when the calibration item is carried out according to the reaction data of the calibration product about the N times of calibration tests of the calibration item, and prompting a reason and/or giving an alarm when the stability is judged to be poor.
14. A sample analysis apparatus, comprising: a sample component, a reagent component, an analysis component, a controller, and a display;
the sample part is used for bearing a sample to be tested, sucking the sample and then providing the sample to the analysis part;
the reagent part is used for bearing a reagent, and the reagent is sucked and then provided for the analysis part;
the analysis component is used for acquiring and analyzing reaction data of the sample and the reagent to obtain a test result;
the controller is used for determining a calibration product and calibration items thereof; according to the determined calibration product and the calibration items thereof, acquiring reaction data of the calibration product about N times of calibration tests of the calibration items, wherein N is a natural number not less than 2;
and the display is used for displaying the reaction data of the N times of calibration tests on the same calibration data interface.
15. The sample analysis device of claim 14, wherein the controller, in response to an instruction from a user to display all of the curves, controls a display to display reaction data of the calibrator with respect to N calibration tests of the calibration item on a same calibration data interface.
16. The sample analysis device of claim 15, wherein the calibration data interface comprises an all-curve control through which the controller receives the instructions to present all curves.
17. The sample analyzer of claim 16, wherein the all-curve control is a check box, and when the check box is checked, the controller receives the command for showing all the curves, and otherwise, the controller does not receive the command for showing all the curves.
18. The sample analysis device of claim 17, wherein the controller is further configured to determine calibration time points, wherein each calibration time point corresponds to a calibration test; according to the determined calibrator, the calibration items and the calibration time points of the calibrator, acquiring reaction data of the calibrator about a single calibration test corresponding to the calibration items at the calibration time points; when the instruction for displaying all the curves is not received, controlling a display to display only the reaction data of the calibrator about the single calibration test corresponding to the calibration item at the calibration time point on the calibration data interface.
19. The sample analysis device according to any one of claims 14 to 18, wherein the calibration data interface comprises a curve display area and/or a numerical display area; the curve display area displays reaction data in a coordinate drawing point mode; the digital display area displays the reaction data in a digital list mode.
20. The sample analyzing apparatus according to claim 19, wherein the controller further determines a parameter to be displayed in the reaction data in response to a parameter selection instruction of the reaction data; and the controller controls the display to display parameters required to be displayed in the reaction data on the calibration data interface.
21. The apparatus of claim 20, wherein the controller further captures a cursor position of the curve display area, and controls the display to display the coordinate value of the point in the vicinity of the point in the form of a numerical value when the cursor position is determined to be within a predetermined range of the point depicted in the curve display area.
22. The sample analysis device according to claim 20 or 21, wherein the calibration data interface comprises a plurality of check boxes, each check box corresponding to a parameter in the reaction data; and any check box is checked to show that the controller receives a selection instruction of the corresponding parameter in the reaction data and determines that the parameter corresponding to the check box needs to be displayed in the reaction data.
23. The sample analysis device of claim 21, wherein the check boxes comprise a check box corresponding to the dominant wavelength in the reaction data, a check box corresponding to the secondary wavelength in the reaction data, and a check box corresponding to the subtraction of the dominant wavelength from the secondary wavelength in the reaction data.
24. The sample analysis device of claim 20, wherein the display displays different parameters to be displayed in the reaction data in different colors in the calibration data interface.
25. The sample analysis device of claim 14, wherein the calibration data interface further comprises a curve adjustment control through which the controller receives a curve adjustment instruction;
the controller is responsive to the curve adjustment instructions to adjust the ordinate scale of the coordinates in the curve display area such that different response data or different parameters of the same response data displayed by the display do not visually coincide together.
26. The sample analyzer of claim 14, wherein the controller determines the stability of the calibration article when performing the calibration item based on the reaction data of the calibration article with respect to the N calibration tests of the calibration item, and indicates a cause and/or issues an alarm when determining that the stability is poor.
27. A computer-readable storage medium, characterized by comprising a program executable by a processor to implement the method of any one of claims 1 to 13.
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