CN111372586B - 包含chp的骨丢失疾病的预防、改善或治疗用组合物 - Google Patents
包含chp的骨丢失疾病的预防、改善或治疗用组合物 Download PDFInfo
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- CN111372586B CN111372586B CN201880074979.3A CN201880074979A CN111372586B CN 111372586 B CN111372586 B CN 111372586B CN 201880074979 A CN201880074979 A CN 201880074979A CN 111372586 B CN111372586 B CN 111372586B
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- China
- Prior art keywords
- bone
- chp
- present
- composition
- bone loss
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/30—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/52—Sperm; Prostate; Seminal fluid; Leydig cells of testes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/306—Foods, ingredients or supplements having a functional effect on health having an effect on bone mass, e.g. osteoporosis prevention
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Cell Biology (AREA)
- Reproductive Health (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Biotechnology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Developmental Biology & Embryology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Botany (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Alternative & Traditional Medicine (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Inorganic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20170154820 | 2017-11-20 | ||
| KR10-2017-0154820 | 2017-11-20 | ||
| PCT/KR2018/014275 WO2019098811A2 (ko) | 2017-11-20 | 2018-11-20 | Chp(시클로-히스프로)를 포함하는 골 손실 질환의 예방, 개선 또는 치료용 조성물 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN111372586A CN111372586A (zh) | 2020-07-03 |
| CN111372586B true CN111372586B (zh) | 2023-07-25 |
Family
ID=66538798
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201880074979.3A Active CN111372586B (zh) | 2017-11-20 | 2018-11-20 | 包含chp的骨丢失疾病的预防、改善或治疗用组合物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US11975041B2 (enExample) |
| EP (1) | EP3714885B1 (enExample) |
| JP (1) | JP6944221B2 (enExample) |
| KR (1) | KR102163445B1 (enExample) |
| CN (1) | CN111372586B (enExample) |
| WO (1) | WO2019098811A2 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102115353B1 (ko) * | 2019-05-17 | 2020-05-26 | 주식회사 노브메타파마 | Chp(사이클로-히스프로) 및 부갑상선 호르몬을 포함하는 골 손실 질환의 예방, 개선 또는 치료용 조성물 |
| WO2022038560A1 (en) * | 2020-08-20 | 2022-02-24 | Novmetapharma Co., Ltd. | Method for treating inflammatory bowel diseases |
| KR102575908B1 (ko) * | 2020-12-11 | 2023-09-07 | 전남대학교산학협력단 | 락토바실러스 사케이 배양액 유래 사이클로디펩티드계 화합물의 분리방법 및 이를 포함하는 골 질환 예방 또는 치료용 조성물 |
| KR20250093685A (ko) | 2023-12-15 | 2025-06-25 | 주식회사 노브메타파마 | 사이클로-히스프로(chp)를 포함하는 운동수행능력 향상, 근 기능 개선 또는 근육 질환 예방, 개선 또는 치료용 조성물 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1990008583A2 (en) * | 1989-02-03 | 1990-08-09 | Walter Pierpaoli | Thyroleberin as immunomodulator and lipid regulator |
| CN1093090A (zh) * | 1992-11-06 | 1994-10-05 | 默克专利股份有限公司 | 环状肽 |
| CN104971086A (zh) * | 2014-04-09 | 2015-10-14 | 台北医学大学 | 兔尾草于促进骨生成或提供神经保护之用途 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5418218A (en) * | 1992-07-10 | 1995-05-23 | The University Of Maryland At Baltimore | Histidyl-proline diketopiperazine (cyclo his-pro) a cns-active pharmacologic agent |
| US5834032A (en) * | 1997-08-11 | 1998-11-10 | Song; Moon K. | Compositions and methods for treating diabetes |
| WO2000020024A2 (en) * | 1998-10-02 | 2000-04-13 | Celtrix Pharmaceuticals, Inc. | Methods for the treatment of non-thyroid disorders |
| CA2382666A1 (en) | 1999-08-23 | 2001-03-01 | The Administrators Of The Tulane Educational Fund | Modulation of the blood-brain barrier transporter for leptin |
| JP5073153B2 (ja) | 2001-06-01 | 2012-11-14 | ノバルティス アーゲー | 副甲状腺ホルモンおよびカルシトニンの経口投与 |
| JP2007525472A (ja) | 2003-07-04 | 2007-09-06 | ニコメド ダンマーク エイピーエス | 経口使用のための副甲状腺ホルモン(pth)含有医薬組成物 |
| CN100509008C (zh) * | 2004-04-12 | 2009-07-08 | 赵晓昂 | 舒痛方及其制剂和用途 |
| CN100548332C (zh) * | 2005-05-26 | 2009-10-14 | 赵晓昂 | 复方栀豉甘总提取物及其制剂和用途 |
| CA2625084A1 (en) | 2005-10-06 | 2007-04-19 | Nastech Pharmaceutical Company Inc. | Pth formulations and methods of use |
| WO2007066841A1 (en) | 2005-12-09 | 2007-06-14 | Serombio Co., Ltd. | Yeast hydrolysate containing cyclo-his-pro and method for producing the same |
| CN101125201A (zh) | 2006-08-17 | 2008-02-20 | 石家庄欧意药业有限公司 | 治疗骨质疏松症或防治由于骨质疏松而导致的骨折的药物组合物及其应用 |
| WO2008109445A1 (en) * | 2007-03-02 | 2008-09-12 | Preventive Nutrient Company, Inc. | Compositions and methods for treating alzheimer's disease and dementia |
| KR100989174B1 (ko) | 2010-02-01 | 2010-10-20 | (주)새롬바이오 | 여성 갱년기 증상개선에 효과를 갖는 효모 가수분해물 및 이를 포함하는 식품 |
| KR101138714B1 (ko) | 2011-07-26 | 2012-04-24 | (주)새롬바이오 | 효모 가수분해물을 유효성분으로 포함하는 연골세포 손상방지 및 재생효과를 갖는 조성물 |
| KR102012554B1 (ko) | 2016-07-13 | 2019-08-23 | 주식회사 노브메타파마 | 사이클로 히스티딘-프롤린을 유효성분으로 포함하는 세포 보호용 조성물 |
-
2018
- 2018-11-20 KR KR1020180143641A patent/KR102163445B1/ko active Active
- 2018-11-20 JP JP2020527807A patent/JP6944221B2/ja active Active
- 2018-11-20 US US16/764,913 patent/US11975041B2/en active Active
- 2018-11-20 WO PCT/KR2018/014275 patent/WO2019098811A2/ko not_active Ceased
- 2018-11-20 EP EP18879826.8A patent/EP3714885B1/en active Active
- 2018-11-20 CN CN201880074979.3A patent/CN111372586B/zh active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1990008583A2 (en) * | 1989-02-03 | 1990-08-09 | Walter Pierpaoli | Thyroleberin as immunomodulator and lipid regulator |
| CN1093090A (zh) * | 1992-11-06 | 1994-10-05 | 默克专利股份有限公司 | 环状肽 |
| CN104971086A (zh) * | 2014-04-09 | 2015-10-14 | 台北医学大学 | 兔尾草于促进骨生成或提供神经保护之用途 |
Non-Patent Citations (1)
| Title |
|---|
| "Distribution and metabolism of Cyclo (His-Pro): A new member of the neuropeptide family";Chandan Prasad 等;《Peptides》;第3卷(第3期);第591-598页 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3714885B1 (en) | 2024-07-31 |
| EP3714885A2 (en) | 2020-09-30 |
| CN111372586A (zh) | 2020-07-03 |
| EP3714885A4 (en) | 2021-08-18 |
| KR20190058346A (ko) | 2019-05-29 |
| JP6944221B2 (ja) | 2021-10-06 |
| KR102163445B1 (ko) | 2020-10-07 |
| US20200338156A1 (en) | 2020-10-29 |
| WO2019098811A3 (ko) | 2019-07-11 |
| US11975041B2 (en) | 2024-05-07 |
| JP2021503483A (ja) | 2021-02-12 |
| WO2019098811A2 (ko) | 2019-05-23 |
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