CN111356692A - Ido抑制剂 - Google Patents
Ido抑制剂 Download PDFInfo
- Publication number
- CN111356692A CN111356692A CN201880074353.2A CN201880074353A CN111356692A CN 111356692 A CN111356692 A CN 111356692A CN 201880074353 A CN201880074353 A CN 201880074353A CN 111356692 A CN111356692 A CN 111356692A
- Authority
- CN
- China
- Prior art keywords
- compound
- group
- solution
- pharmaceutically acceptable
- added
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (14)
- PCT国内申请,权利要求书已公开。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201711375318 | 2017-12-19 | ||
CN2017113753188 | 2017-12-19 | ||
PCT/CN2018/122015 WO2019120212A1 (zh) | 2017-12-19 | 2018-12-19 | Ido抑制剂 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN111356692A true CN111356692A (zh) | 2020-06-30 |
CN111356692B CN111356692B (zh) | 2021-09-03 |
Family
ID=66993093
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201880074353.2A Active CN111356692B (zh) | 2017-12-19 | 2018-12-19 | Ido抑制剂 |
Country Status (3)
Country | Link |
---|---|
CN (1) | CN111356692B (zh) |
TW (1) | TW201927777A (zh) |
WO (1) | WO2019120212A1 (zh) |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002028846A1 (en) * | 2000-10-03 | 2002-04-11 | Dupont Pharmaceuticals Company | Cyclic sulfonyl compounds as inhibitors of metalloproteases |
WO2003020699A2 (en) * | 2001-08-30 | 2003-03-13 | Merck & Co., Inc. | Tyrosine kinase inhibitors |
WO2006062982A2 (en) * | 2004-12-07 | 2006-06-15 | Locus Pharmaceuticals, Inc. | Urea inhibitors of map kinases |
CN104619709A (zh) * | 2012-07-13 | 2015-05-13 | Ucb生物制药私人有限公司 | 作为tnf活性调节剂的咪唑并吡啶衍生物 |
WO2017079519A1 (en) * | 2015-11-06 | 2017-05-11 | Incyte Corporation | Heterocyclic compounds as pi3k-gamma inhibitors |
CN106715417A (zh) * | 2014-04-04 | 2017-05-24 | 爱欧梅特制药公司 | 药物中使用的吲哚衍生物 |
CN106905256A (zh) * | 2017-03-06 | 2017-06-30 | 中国药科大学 | 苯并五元杂环类ido1抑制剂、其制备方法及应用 |
WO2017161028A1 (en) * | 2016-03-16 | 2017-09-21 | Kura Oncology, Inc. | Substituted inhibitors of menin-mll and methods of use |
-
2018
- 2018-12-19 CN CN201880074353.2A patent/CN111356692B/zh active Active
- 2018-12-19 WO PCT/CN2018/122015 patent/WO2019120212A1/zh active Application Filing
- 2018-12-19 TW TW107145936A patent/TW201927777A/zh unknown
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002028846A1 (en) * | 2000-10-03 | 2002-04-11 | Dupont Pharmaceuticals Company | Cyclic sulfonyl compounds as inhibitors of metalloproteases |
WO2003020699A2 (en) * | 2001-08-30 | 2003-03-13 | Merck & Co., Inc. | Tyrosine kinase inhibitors |
WO2006062982A2 (en) * | 2004-12-07 | 2006-06-15 | Locus Pharmaceuticals, Inc. | Urea inhibitors of map kinases |
CN104619709A (zh) * | 2012-07-13 | 2015-05-13 | Ucb生物制药私人有限公司 | 作为tnf活性调节剂的咪唑并吡啶衍生物 |
CN106715417A (zh) * | 2014-04-04 | 2017-05-24 | 爱欧梅特制药公司 | 药物中使用的吲哚衍生物 |
WO2017079519A1 (en) * | 2015-11-06 | 2017-05-11 | Incyte Corporation | Heterocyclic compounds as pi3k-gamma inhibitors |
WO2017161028A1 (en) * | 2016-03-16 | 2017-09-21 | Kura Oncology, Inc. | Substituted inhibitors of menin-mll and methods of use |
CN106905256A (zh) * | 2017-03-06 | 2017-06-30 | 中国药科大学 | 苯并五元杂环类ido1抑制剂、其制备方法及应用 |
Also Published As
Publication number | Publication date |
---|---|
TW201927777A (zh) | 2019-07-16 |
WO2019120212A1 (zh) | 2019-06-27 |
CN111356692B (zh) | 2021-09-03 |
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Legal Events
Date | Code | Title | Description |
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PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20201029 Address after: Unit E168 North building two building in Suzhou City, Jiangsu province Suzhou Industrial Park 215123 Xinghu Street No. 218 BioBAY building A1 Applicant after: Cstone Pharmaceuticals (Suzhou) Co.,Ltd. Applicant after: Cstone Pharmaceuticals (Shanghai) Co.,Ltd. Applicant after: Keystone Address before: Unit E168 North building two building in Suzhou City, Jiangsu province Suzhou Industrial Park 215123 Xinghu Street No. 218 BioBAY building A1 Applicant before: Cstone Pharmaceuticals (Suzhou) Co.,Ltd. Applicant before: Cstone Pharmaceuticals (Shanghai) Co.,Ltd. Applicant before: Keystone Applicant before: Nanjing Mingde New Drug Development Co.,Ltd. |
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GR01 | Patent grant | ||
GR01 | Patent grant |