CN111346168A

CN111346168A - Medicine for treating oral ulcer and preparation method thereof

Info

Publication number: CN111346168A
Application number: CN202010348790.8A
Authority: CN
Inventors: 郑培乐
Original assignee: Individual
Current assignee: Individual
Priority date: 2020-04-28
Filing date: 2020-04-28
Publication date: 2020-06-30

Abstract

The invention relates to a traditional Chinese medicine for treating diseases, in particular to a medicine for treating oral ulcer and a preparation method thereof. The formula of the invention is as follows: 20-30 parts of coptis chinensis, 10-15 parts of indigo naturalis, 5-6 parts of borneol, 5-7 parts of gypsum, 5-6 parts of borax, 7-10 parts of mint, 5-6 parts of rhizoma anemarrhenae and a proper amount of sesame oil. The medicine provided by the invention can fully improve local ulcer tissues and repair and heal the local ulcer tissues early to achieve the purpose of treatment, and the medicine has no side effect.

Description

Medicine for treating oral ulcer and preparation method thereof

Technical Field

The invention relates to a medicine for treating oral ulcer and a preparation method thereof.

Background

The oral ulcer is a common oral mucosa disease, the prevalence rate is about 20%, mucosa damage appears at any position on the oral mucosa surface periodically, simultaneously burning pain with different degrees is accompanied, language and food are influenced, the treatment effect is not obvious, the existing common treatment methods mainly comprise Chinese patent medicine powder, vitamin medicines and some patches, the administration time is long, the effect is not ideal, and patients are dissatisfied.

Disclosure of Invention

The traditional Chinese medicine preparation aims at overcoming the defects, and provides the medicine for treating the oral mucosa ulcer, which has the advantages of definite curative effect, quick response and no side effect.

The formula of the invention is as follows: the components comprise the following components in parts by weight: 20-30 parts of coptis chinensis, 10-15 parts of indigo naturalis, 5-6 parts of borneol, 5-7 parts of gypsum, 5-6 parts of borax, 7-10 parts of mint, 5-6 parts of rhizoma anemarrhenae and a proper amount of sesame oil.

The components comprise the following components in parts by weight: 20-25 parts of coptis chinensis, 12-14 parts of indigo naturalis, 5-6 parts of borneol, 5-6 parts of gypsum, 5-6 parts of borax, 8-9 parts of mint, 5-6 parts of rhizoma anemarrhenae and a proper amount of sesame oil.

The dosage of the sesame oil is that 0.6 to 0.9ml of sesame oil is added into each gram of the total mass of the coptis root, the natural indigo, the borneol, the gypsum, the borax, the mint and the rhizoma anemarrhenae.

Pulverizing Coptidis rhizoma, indigo naturalis, Borneolum Syntheticum, Gypsum Fibrosum, Borax, herba Menthae, and rhizoma anemarrhenae respectively at required mass ratio, sieving with 60-80 mesh sieve, mixing the components passing through the sieve, adding oleum Sesami, and stirring to obtain paste.

The addition amount of the sesame oil is that 0.6-0.9mL of sesame oil is added per gram, preferably 0.7-0.8mL, based on the total mass of coptis chinensis, indigo naturalis, borneol, gypsum, borax, mint and rhizoma anemarrhenae.

The traditional Chinese medicine preparation is applied to the affected part of the oral mucosa ulcer twice a day, and is applied to the affected part once, the affected part is coated with one layer of the traditional Chinese medicine preparation, the cure rate after 1-2 times of application is about 55 percent, the cure rate after 3-4 times of application is about 35 percent, and the rest 10 percent of people are completely cured after 5-6 times of application.

The medicine provided by the invention can fully improve the early repair and recovery of the affected tissues of the oral mucosa, achieves the purpose of treatment, and has no side effect.

Introduction of medicines:

coptis chinensis: it is mainly used for purging fire and removing toxicity, and can be used for treating excessive fire, conjunctival congestion, and aphtha of the mouth and tongue.

Indigo naturalis: mainly has the functions of clearing away heat and toxic material, cooling blood and arresting convulsion.

Mint: mainly has the functions of clearing and relieving throat, contracting mucosa blood vessels and paralyzing peripheral nerves, and the mint is dried mint and is used as a medicine by the whole herb.

Gypsum: mainly aims at clearing heat and purging fire, astringing and promoting granulation.

Borneol: mainly has the functions of clearing away heat and toxic materials and promoting resuscitation.

Borax: mainly for clearing away heat and toxic materials.

Rhizoma anemarrhenae: it is mainly used to purge fire and relieve restlessness.

The invention has good curative effect on the following diseases:

brief introduction of the disorders:

(1) the recurrent oral ulcer has unknown reason, the oral morbidity is about 20 percent, and the course of disease is 7 to 14 days.

(2) About 30-90% of the sera of residents with oral mucosal ulceration in children caused by herpes simplex virus type 1 have antibodies against herpes simplex virus, indicating that it has developed a viral infection.

(3) The hand-foot-and-mouth disease is characterized in that small blisters can be seen on skin, oral mucosa, palms and soles caused by the coxsackie virus A16, and ulceration is formed after ulceration.

(4) Herpetic pharyngolaryngitis is a clinical symptom such as oral mucosa ulcer caused by coxsackie virus A4, and incapability of eating by children after ulceration of soft palate, uvula, tonsil and small blister.

(5) The thrush is a common oral candidiasis, and the children have food refusal and cry after suffering from the thrush. With the most common neonates, the incidence rate is 4%.

The invention has the beneficial effects that:

(1) the treatment effect on the dental ulcer is exact, and the medication time is short;

(2) the medicine has good repeated use effect, can prolong the interval time of recurrent oral ulcer, shorten the course of disease, and finally ensure that the oral ulcer of a patient does not relapse or reduces the relapse, and has special curative effect on the oral ulcer of infants caused by virus.

The disease symptoms of the invention, especially the lesions of oral mucosa ulcer caused by herpes simplex virus type 1 infection, hand-foot-and-mouth disease caused by coxsackie virus A16 infection, mucosa ulcer caused by coxsackie virus A4 infection and mucosa lesion caused by candida albicans of children patients under 6 years old, have obvious effect.

The existing oral ulcer medicines for herpes simplex virus and coxsackie virus A16 infection by oral administration are as follows: acyclovir tablets and acyclovir are commonly used, and the recovery of the disease is slow. The medicament prepared from the Chinese herbal medicine formula medicament has short administration time and definite curative effect on the oral mucosa ulcer, and is an ideal medicament for treating the oral ulcer at present.

DETAILED DESCRIPTION OF EMBODIMENT (S) OF INVENTION

Example 1:

according to the mass; the components are as follows: 20 g of coptis chinensis, 10 g of indigo naturalis, 5 g of borneol, 5 g of gypsum, 5 g of borax, 7 g of mint and 5 g of rhizoma anemarrhenae, which are respectively crushed and sieved by a 60-mesh sieve, 40mL of sesame oil is added to be stirred and blended into paste for later use, and the paste is applied to an affected part for 2 times a day for external use.

Application example 1

Von Gong, female, 20 days of birth

The main complaints are: (parent/parent) milk refusal for 3 days

The current medical history: the patient does not eat milk, cry and fall asleep for 3 days, and the diagnosis and treatment are carried out

Checking: the middle part of the tongue surface has one big ulcer of mung bean

And (3) diagnosis: ulcer of oral mucosa

Treatment: the affected part of the traditional Chinese medicine prepared in the embodiment 1 of the invention is smeared by a special oral cavity concoction knife (twice a day), and a little milk can be taken in the afternoon in sequence (smearing the affected part in the morning), the affected part does not cry, and the affected part is smeared once at 6 pm on the same day, so that the mother says that: the sleeping is good at night, all are normal, the plaster is applied once again for the next day for consolidation, the parents are satisfied after three days, and the ulcer surface is recovered completely as before.

Example 2:

according to the mass; the components are as follows: 20 g of coptis chinensis, 15 g of indigo naturalis, 5 g of borneol, 5 g of gypsum, 5 g of borax, 10 g of mint and 5 g of rhizoma anemarrhenae, which are respectively crushed and sieved by a 60-mesh sieve, 45mL of sesame oil is added to be stirred and blended into paste for later use, and the paste is applied to an affected part for 2 times per day for external use.

Application example 2

Hu Zhi, woman, 4 years old

The main complaints are: (parent: a day without eating and crying

The current medical history: in the middle of the day, the patient has fever of 37.8 degrees, cannot eat and cry.

Checking that tonsil is enlarged by ② degrees and the surface has a plurality of ulcer points which are similar to rice grains

And (3) diagnosis: tonsillitis (tonsillitis)

The etiology is as follows: caused by coxsackievirus A4

Treatment: the traditional Chinese medicine prepared in the embodiment 2 of the invention is used above the tonsil tissue, the tonsil is contacted when the traditional Chinese medicine is swallowed, the treatment effect is achieved, the medicine is applied to the affected part of the oral cavity by using the special blending knife for the oral cavity once, and the mother can eat food

The effect is as follows: the application is carried out once, the mother is satisfied, and the ulcer point is recovered as before after one day.

Example 3:

according to the mass; the components are as follows: 30 g of coptis chinensis, 15 g of indigo naturalis, 5 g of borneol, 5 g of gypsum, 5 g of borax, 8 g of mint and 5 g of rhizoma anemarrhenae, which are respectively crushed and sieved by a 60-mesh sieve, 51mL of sesame oil is added to be stirred and blended into paste for later use, and the paste is applied to an affected part for 2 times per day for external use.

Application example 3

Wu-Chi, woman in 11 months

The main complaints are: (mother's note) can't eat milk, cry for 3 days

The current medical history: the body temperature is 38.6 ℃ in 3 days of fever, the people do not feel milk when running out of water, and the people do not sleep when crying and screaming at night.

Checking: the mucous membranes of the cheeks on both sides are obviously congested and have many ulcer points on the tonsil

And (3) diagnosis: oral ulcer

The etiology is as follows: herpes simplex virus type 1 infection

Treatment: the traditional Chinese medicine prepared in the embodiment 3 of the invention is applied to the affected part of the oral cavity for 2 times, namely, the affected part is applied with the formula medicine respectively at 9 am on the current day and 1 time at 5 pm on the same day.

The effect is as follows: the child mother can eat the cake and drink water after saying 5 times of medication and going home, which indicates satisfaction, and the ulcer point is recovered as good as before after one day.

Example 4:

according to the mass; the components are as follows: 30 g of coptis chinensis, 10 g of indigo naturalis, 6 g of borneol, 5 g of gypsum, 6 g of borax, 8 g of mint and 5 g of rhizoma anemarrhenae, which are respectively crushed and sieved by a 60-mesh sieve, 49mL of sesame oil is added to be stirred and blended into paste for later use, and the paste is applied to an affected part for 2 times per day for external use.

Application example 4

From one woman, age 1

The main complaints are: (mother's) oral cavity ulceration for 2 days

The current medical history: when the children suffer from fever for two days, the children still have food refusal, running water, crying and screaming, do not sleep at night, and the children self-use external powder, which has poor effect.

Checking: the large ulcer points of the small rice grains on the two side buccal mucosa are respectively one, the large ulcer of the soybeans on the 3 sides of the tongue frenulum, tonsil swelling and 3 ulcer points on the surface are formed.

And (3) diagnosis: ulcer of oral mucosa

The etiology is as follows: caused by herpes simplex virus type 1 infection

Treatment: the formula medicine of the invention in the embodiment 4 is applied to the affected part twice in the day, wherein the application is respectively carried out at 9 am and 3 pm on the same day.

The effect is as follows: mother says that: the mother can tell the day to sleep in the same day, and eat normal at night without crying and screaming, the sleep is good, the effect is satisfied after twice taking medicine, and the ulcer point is recovered as good as before.

Example 5:

according to the mass; the components are as follows: 20 g of coptis chinensis, 10 g of indigo naturalis, 5 g of borneol, 5 g of gypsum, 6 g of borax, 8 g of mint and 5 g of rhizoma anemarrhenae, which are respectively crushed and sieved by a 60-mesh sieve, 42mL of sesame oil is added to be stirred and blended into paste for later use, and the paste is applied to an affected part for 2 times per day for external use.

Application example 5

Ma Chi, woman, 2 years old

The main complaints are: crying did not eat for 4 days.

The current medical history: refusing food, running water, crying, lassitude and no sleep at night after 4 days, and self-administration of vitamin B₁,B₂C, no obvious effectTo diagnose and treat.

Checking: the upper and lower lips and soft palate of the buccal mucosa at both sides are covered by white false membranes

And (3) diagnosis: aphtha (thrush)

The etiology is as follows: caused by oral Candida albicans

Treatment: at the time of diagnosis, 9 o 'clock, the formula of the medicine in example 5 is smeared on the affected part once, a little meal can be eaten after the return, the medicine is smeared again at 3 o' clock and 30 min afternoon on the same day, and the medicine is taken once on the affected part in the morning on the next day

The effect is as follows: the mother can eat normally in the evening without crying and sleep well

The effect is satisfied after 3 times of medication, and no white false membrane covers after one day.

Example 6:

according to the mass; the components are as follows: 20 g of coptis chinensis, 15 g of indigo naturalis, 6 g of borneol, 5 g of gypsum, 6 g of borax, 9 g of mint and 5 g of rhizoma anemarrhenae, which are respectively crushed and sieved by a 60-mesh sieve, 47mL of sesame oil is added to be stirred and blended into paste for later use, and the paste is applied to an affected part for 2 times per day for external use.

Application example 6

Wangzhi, woman in 14 months

The main complaints are: (maternal) diarrhea and fever 38 degrees before two days

The current medical history: diarrhea, fever 38 degrees, oral paracetamol fever, running water in the mouth for nearly three days, milk refusal, crying and crying, lassitude, and the patient can not sleep at night.

Checking: one ulcer in the tip of the tongue, one ulcer in the left side of the lower lip and one large ulcer in the small rice, tonsil congestion.

And (3) diagnosis: ulcer of oral mucosa

The etiology is as follows: caused by herpes simplex virus type 1

Treatment: the medicine prepared in example 6 was applied to the affected part once at 10 am and 3.30 pm on the same day.

The effect is as follows: mother says that all the daughter recovers to normal, the affected part uses the medicine with the formula twice, the effect is satisfactory, and the ulcer surface is recovered to be perfect as before.

Example 7:

according to the mass; the components are as follows: 20 g of coptis chinensis, 15 g of indigo naturalis, 6 g of borneol, 5 g of gypsum, 6 g of borax, 8 g of mint and 5 g of rhizoma anemarrhenae, which are respectively crushed and sieved by a 60-mesh sieve, 45mL of sesame oil is added to be stirred and blended into paste for later use, and the paste is applied to an affected part for 2 times per day for external use.

Application example 7

Song Dynasty, male, 15 months

The main complaints are: (mother-stated) tongue ulcer for two days

The current medical history: tongue ulcer can not be taken with milk, running water and crying for two days, and can be diagnosed by introduction: bilateral gingival ulcer of upper jaw

And (3) diagnosis: ulcer of oral mucosa

The etiology is as follows: caused by herpes simplex virus type 1

Treatment: the formula prepared in example 7 is applied to the affected part once

The effect is as follows: the medicine is applied once, the telephone call is made, the patient can eat the medicine after half an hour, all the medicine is recovered to be normal, and the ulcer surface is recovered to be intact as before after one day.

Example 8:

according to the mass; the components are as follows: 30 g of coptis chinensis, 15 g of indigo naturalis, 6 g of borneol, 5 g of gypsum, 6 g of borax, 8 g of mint and 5 g of rhizoma anemarrhenae, which are respectively crushed and sieved by a 60-mesh sieve, 53mL of sesame oil is added to be stirred and blended into paste for later use, and the paste is applied to an affected part for 2 times per day for external use.

Application example 8

For 9 months for male

The main complaints are: (mother prescription) refusal to eat for one day

The current medical history: the fever is 37.6 degrees in one day before the visit and is 39.6 degrees at night, a certain brand of Meilin antipyretic is orally taken, the new children anti-inflammatory drug is used, the fever is 38 degrees in the morning, the patient has food refusal, the patient has watery mouth, the patient does not feel lassitude, and the patient does not cry and sleep.

Checking: the right upper jaw gum has one large ulcer, swollen tonsil and 3 large ulcer surfaces with rice grains

And (3) diagnosis: ulcer of oral mucosa

The etiology is as follows: caused by herpes simplex virus type 1

Treatment: at 3 pm of the current day, the affected part is coated with the medicine prepared by the formula of example 8 once, and 5 o' clock after home can take milk

The effect is as follows: the effect is satisfied after once application, and the ulcer surface is recovered as good as before after one day.

Example 9:

according to the mass; the components are as follows: 30 g of coptis chinensis, 10 g of indigo naturalis, 6 g of borneol, 5 g of gypsum, 6 g of borax, 8 g of mint and 5 g of rhizoma anemarrhenae, which are respectively crushed and sieved by a 60-mesh sieve, 50mL of sesame oil is added to be stirred and blended into paste for later use, and the paste is applied to an affected part for 2 times per day for external use.

Application example 9

Schedule, male, 2 years old

The main complaints are: (maternal) eating-failure for 2 days

The current medical history: fever of 38.2 degrees, food refusal, running water, crying and screaming, poor sleep, amoxicillin oral administration, radix isatidis, common cold and no pain, fever of 39 degrees in the morning before the visit, and the treatment.

Checking: 20 or more ulcer spots of lower lip and double buccal mucosa, and pimples of hand and foot skin

And (3) diagnosis: hand-foot-and-mouth disease

The etiology is as follows: caused by infection of coxsackievirus A16

Treatment: the Chinese medicine prepared in example 9 is applied to the affected parts of 30 parts from 3 pm on the current day of the clinic, and the affected parts are used once every day at 8 am and 4 pm

The effect is as follows: the mother says that the mother can eat things while sleeping, the difference is poor, the three times of the common medicines show that the satisfaction is achieved, and the ulcer surface is recovered to be intact as before after two days.

Example 10:

according to the mass; the components are as follows: 25 g of coptis chinensis, 10 g of natural indigo, 6 g of borneol, 5 g of gypsum, 6 g of borax, 8 g of mint and 5 g of rhizoma anemarrhenae, which are respectively crushed and sieved by a 60-mesh sieve, 45mL of sesame oil is added to be stirred and blended into paste for later use, and the paste is applied to an affected part for 2 times per day for external use.

Application example 10

Wangzhi, women, age 6

The main complaints are: (mother prescription) oral ulcer for two days

The current medical history: oral ulcer is found in the evening before the visit, and a plurality of red herpes can be seen on hands and feet

Checking: there is an ulcer on the buccal mucosa and herpes between hands and feet

And (3) diagnosis: hand-foot-and-mouth disease

The etiology is as follows: coxsackievirus A16

Treatment: the formula medicine prepared in the example 10 has the effect of being applied to affected parts once in the morning and afternoon: the next day, the mother says that the effect is good, all the things are recovered to be normal, and the ulcer surface is recovered to be intact as before.

Example 11:

according to the mass; the components are as follows: 25 g of coptis chinensis, 15 g of indigo naturalis, 6 g of borneol, 5 g of gypsum, 6 g of borax, 8 g of mint and 5 g of rhizoma anemarrhenae, which are respectively crushed and sieved by a 60-mesh sieve, 49mL of sesame oil is added to be stirred and blended into paste for later use, and the paste is applied to an affected part for 2 times per day for external use.

Application example 11

Zhangqi, male, 5 years old

The main complaints are: (mother prescription) refusal for 1 day

The current medical history: fever of 37.4 degrees before treatment, fever abating due to oral anti-inflammatory drugs and incapability of eating, and treatment by introduction

Checking: two ulcers on the lower lip mucosa, one ulcer on each of the buccal mucosa on both sides, and multiple red herpes on hands and feet

And (3) diagnosis: hand-foot-and-mouth disease

The etiology is as follows: caused by infection of coxsackievirus A16

Treatment: the affected area was coated 1 time with the pharmaceutical formulation prepared in example 11,

the effect is as follows: after the medicine is taken once, the symptoms disappear, and the family members are satisfied.

Example 12:

according to the mass; the components are as follows: 30 g of coptis chinensis, 15 g of indigo naturalis, 6 g of borneol, 7 g of gypsum, 6 g of borax, 10 g of mint and 5 g of rhizoma anemarrhenae, which are respectively crushed and sieved by a 60-mesh sieve, 55mL of sesame oil is added, the mixture is stirred and blended into paste for later use, and the paste is applied to an affected part for 2 times every day for external use.

Application example 12

Zhangqi for women, 59 years old

The main complaints are: ulcer for 4 days

The current medical history: oral ulcer of oral mucosa for 5 years or more, 7-8 times per year, and oral administration for each timeVitamin B₂Liushen Wan, the curative effect is not ideal.

Checking: lower lip mucosa soybean canker

And (3) diagnosis: recurrent oral ulcer

Treatment: the formula prepared in example 12 is coated on the ulcer surface twice daily

The effect is as follows: the medicine is taken for 2 times, the meal is normal, and the ulcer surface recovers as before after two days.

Example 13:

according to the mass; the components are as follows: 25 g of coptis chinensis, 15 g of natural indigo, 5 g of borneol, 5 g of gypsum, 5 g of borax, 10 g of mint and 5 g of rhizoma anemarrhenae, which are respectively crushed and sieved by a 60-mesh sieve, 52mL of sesame oil is added to be stirred and blended into paste for later use, and the paste is applied to an affected part for 2 times per day for external use.

Application example 13

Liu Gong, female, age 32

The main complaints are: oral ulcer for 3 days

The current medical history: the history of oral mucosa ulcer is 1 year, mucosa ulcer appears alternately, each recurrence is more than one week, vitamin B2 is applied to affected part for each time, sublingual mucosa nanoparticle ulcer is 3 days, and the powder is used for treating disease

Checking: three ulcers of rice grains on left lower mucosa of tongue

And (3) diagnosis: recurrent oral ulcer

Treatment: the formulation prepared in example 13 was applied to the affected area once

The effect is as follows: the patients are satisfied after the medicine is applied, and the patients can be better without taking the medicine when the patients call for follow-up and then have ulcer for 1-2 days.

Example 14:

according to the mass; the components are as follows: 20 g of coptis chinensis, 15 g of indigo naturalis, 5 g of borneol, 5 g of gypsum, 5 g of borax, 10 g of mint and 6 g of rhizoma anemarrhenae, which are respectively crushed and sieved by a 60-mesh sieve, 47mL of sesame oil is added to be stirred and blended into paste for later use, and the paste is applied to an affected part for 2 times per day for external use.

Application example 14

Liu Gong, female, age 31

The main complaints are: tongue ulcer for 10 days

The current medical history: oral ulcer 3 years, 2-3 times per year, more times each time, good success at the end of the month, more medicines taken orally and externally, unsatisfactory effect, and treatment by introduction

Checking: 7 parts of the tongue with large grain ulcer at the two side edges

And (3) diagnosis: recurrent oral ulcer

Treatment: visit at 5.30 pm on the same day

The next afternoon at 5 o' clock

The formulation prepared in example 14 was applied to the affected area once each

The following day patients were: after the first medicine is applied, the edge of the right tongue is not painful

The left tongue edge is obviously painless

The effect is as follows: the medicine is taken twice, the satisfaction is achieved, the meal is normal, and the ulcer surface recovers as before after two days.

Example 15:

according to the mass; the components are as follows: 20 g of coptis chinensis, 12 g of indigo naturalis, 5 g of borneol, 5 g of gypsum, 5 g of borax, 8 g of mint and 6 g of rhizoma anemarrhenae, which are respectively crushed and sieved by a 60-mesh sieve, 43mL of sesame oil is added to be stirred and blended into paste for later use, and the paste is applied to an affected part for 2 times per day for external use.

Application example 15:

to the junk head, male, 32 years old

The main complaints are: oral ulcer for 3 days

The current medical history: oral ulcer is cured by introducing the oral ulcer which is aggravated in 25 years, frequently in 3 years and cured 2 times per month in 1-2 weeks

Checking: one ulcer on the right upper buccal mucosa and one ulcer on the right side of the tongue are all rice grains in size

And (3) diagnosis: recurrent oral ulcer

Treatment: at the afternoon of the clinic, 5.30 g of the prescription prepared in example 15 is applied to the ulcer surface

Smearing the paste once again at 7 am

The effect is as follows: the patients were not painful and satisfied the following noon, and the mucosa of the ulcer surface returned to normal after one day.

Example 16:

according to the mass; the components are as follows: 25 g of coptis chinensis, 12 g of indigo naturalis, 5 g of borneol, 5 g of gypsum, 5 g of borax, 8 g of mint and 6 g of rhizoma anemarrhenae, which are respectively crushed and sieved by a 60-mesh sieve, 47mL of sesame oil is added to be stirred and blended into paste for later use, and the paste is applied to an affected part for 2 times per day for external use.

Application example 16

Zhangqi, woman, age 32

The main complaints are: oral ulcer for 3 days

The current medical history: the oral ulcer relapses once every 2-3 months for two years, the effect is good when the oral ulcer is taken for the first time and is not satisfactory when the oral ulcer is taken for the second time after relapsing again, so that treatment by diagnosis is realized

Checking: one large ulcer of mung bean on the right side of the tongue tip

And (3) diagnosis: recurrent oral ulcer

Treatment: coating on the affected part of ulcer surface and using the formula prepared in example 16

The above formula is applied to the affected part at 7 am and 40 min in the morning

The effect is as follows: the affected part is treated twice, and the pain of the patient is relieved.

Comparative example 1:

the formula of a certain traditional Chinese medicine is as follows: 10-15 g of rheum officinale, 15-20 g of indigo naturalis, 7-10 g of borneol, 5-10 g of liquorice, 10-15 g of mirabilite, 7-10 g of pearl powder, 5-10 g of catechu, 7-10 g of borax and a proper amount of sesame oil.

The patients:

when a patient with a certain traditional Chinese medicine formula of comparative example 1 had taken certain oral ulcer (15 months), the patient still cries and still had ulcer surfaces after continuous use for 3 days.

The affected part of the traditional Chinese medicine prepared in the embodiment 2 of the invention is smeared by a special blending knife for oral cavity (twice a day), and the ulcer surface is recovered as good as before after 1 day.

Compared with the invention, the invention has short healing time and repeated effect of a certain formula.

Comparative example 2:

the formula of a certain traditional Chinese medicine is as follows: 10-15 g of rheum officinale, 15-20 g of indigo naturalis, 5-10 g of radix rehmanniae, 5-10 g of radix scutellariae, 5-10 g of liquorice, 5-10 g of catechu and 5-6 g of gypsum.

The patients' von is recurrent oral ulcer, and after using the traditional Chinese medicine formula of comparative example 2 for 3 days, the patients return to normal, but oral ulcer symptoms appear after 5 days.

The affected part of the traditional Chinese medicine prepared in the embodiment 1 of the invention is smeared by a special oral concoction knife (twice a day), the ulcer surface is recovered to be as good as before after 2 days, and no recurrence occurs within 30 days.

Comparative example 3:

the formula of a certain traditional Chinese medicine is as follows: 15-20 g of coptis chinensis, 10-15 g of indigo naturalis, 10-15 g of mint, 5-6 g of borneol, 5-6 g of catechu, 5-10 g of honeysuckle and 5-6 g of gypsum.

The patients:

wangzhi is tongue ulcer, and the Chinese medicinal formula of comparative example 3 is applied to the affected part for 6 days before the affected part becomes healthy.

The embodiment and the application show that the oral ulcer of the infant patient is manifested by oral mucosa ulceration, fever and saliva, food refusal, dysphoria, lassitude, crying at night and other symptoms.

Claims

1. A medicament for treating oral ulcers, which is characterized in that: the components comprise the following components in parts by weight: 20-30 parts of coptis chinensis, 10-15 parts of indigo naturalis, 5-6 parts of borneol, 5-7 parts of gypsum, 5-6 parts of borax, 7-10 parts of mint, 5-6 parts of rhizoma anemarrhenae and a proper amount of sesame oil.

2. The medicament for treating oral ulcers according to claim 1, wherein: the components comprise the following components in parts by weight: 20-25 parts of coptis chinensis, 12-14 parts of indigo naturalis, 5-6 parts of borneol, 5-6 parts of gypsum, 5-6 parts of borax, 8-9 parts of mint, 5-6 parts of rhizoma anemarrhenae and a proper amount of sesame oil.

3. The medicament for treating oral ulcer according to claim 1 or 2, characterized in that: the dosage of the sesame oil is that 0.6-0.9ml of sesame oil is added into each gram of the total mass of the coptis root, the natural indigo, the borneol, the gypsum, the borax, the mint and the rhizoma anemarrhenae.

4. A method for preparing a medicament for treating oral ulcers according to any one of claims 1 to 3, wherein: pulverizing Coptidis rhizoma, indigo naturalis, Borneolum Syntheticum, Gypsum Fibrosum, Borax, herba Menthae, and rhizoma anemarrhenae respectively at required mass ratio, sieving with 60-80 mesh sieve, mixing the components passing through the sieve, adding oleum Sesami, and stirring to obtain paste.

5. The process for preparing a medicament for treating oral ulcers according to claim 4, wherein: the addition amount of the sesame oil is that 0.6-0.9mL of sesame oil is added per gram, preferably 0.7-0.8mL, based on the total mass of the coptis chinensis, the indigo naturalis, the borneol, the gypsum, the borax, the mint and the rhizoma anemarrhenae.