CN111344032A - 新型干粉吸入装置 - Google Patents

新型干粉吸入装置 Download PDF

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Publication number
CN111344032A
CN111344032A CN201880074793.8A CN201880074793A CN111344032A CN 111344032 A CN111344032 A CN 111344032A CN 201880074793 A CN201880074793 A CN 201880074793A CN 111344032 A CN111344032 A CN 111344032A
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capsule
chamber
capsule chamber
dry powder
inhalation device
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CN201880074793.8A
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CN111344032B (zh
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李昌辉
董平
朱雪冰
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Chia Tai Tianqing Pharmaceutical Group Co Ltd
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Chia Tai Tianqing Pharmaceutical Group Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033Details of the piercing or cutting means
    • A61M15/0035Piercing means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033Details of the piercing or cutting means
    • A61M15/0041Details of the piercing or cutting means with movable piercing or cutting means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0003Details of inhalators; Constructional features thereof with means for dispensing more than one drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0005Details of inhalators; Constructional features thereof with means for agitating the medicament
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0005Details of inhalators; Constructional features thereof with means for agitating the medicament
    • A61M15/0006Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means
    • A61M15/0008Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means rotating by airflow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/002Details of inhalators; Constructional features thereof with air flow regulating means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033Details of the piercing or cutting means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0051Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a tape, e.g. strips
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001Particle size control
    • A61M11/003Particle size control by passing the aerosol trough sieves or filters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0021Mouthpieces therefor
    • A61M15/0025Mouthpieces therefor with caps
    • A61M15/0026Hinged caps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00Characteristics of a physical parameter; associated device therefor
    • A61M2206/10Flow characteristics
    • A61M2206/12Flow characteristics the flow being spirally in a plane, e.g. against a plane side of a membrane filter element
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00Characteristics of a physical parameter; associated device therefor
    • A61M2206/10Flow characteristics
    • A61M2206/16Rotating swirling helical flow, e.g. by tangential inflows
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00Characteristics of a physical parameter; associated device therefor
    • A61M2206/10Flow characteristics
    • A61M2206/20Flow characteristics having means for promoting or enhancing the flow, actively or passively

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)

Abstract

一种新型干粉吸入装置,通过对胶囊型干粉吸入装置设置多个并联排布的胶囊室(1a,1b,1c,1d),提供了一种以分离的方式包含组合产品的每种活性组分或其混合物的药物分配器,结构简单,操作方便。此外,每个胶囊室(1a,1b,1c,1d)可根据药物或其组合物的粉末的性质调整进气通道和出气通道的参数,以针对每种活性成分设置其合适的雾粒分布。

Description

PCT国内申请,说明书已公开。

Claims (16)

  1. PCT国内申请,权利要求书已公开。
CN201880074793.8A 2017-11-23 2018-11-22 新型干粉吸入装置 Active CN111344032B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202210022797.XA CN114452496B (zh) 2017-11-23 2018-11-22 新型干粉吸入装置

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201711177647.1A CN109821118A (zh) 2017-11-23 2017-11-23 新型肺部药物输送系统
CN2017111776471 2017-11-23
PCT/CN2018/116942 WO2019101135A1 (zh) 2017-11-23 2018-11-22 新型干粉吸入装置

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CN111344032A true CN111344032A (zh) 2020-06-26
CN111344032B CN111344032B (zh) 2021-12-24

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CN201711177647.1A Pending CN109821118A (zh) 2017-11-23 2017-11-23 新型肺部药物输送系统
CN202210022797.XA Active CN114452496B (zh) 2017-11-23 2018-11-22 新型干粉吸入装置
CN201880074793.8A Active CN111344032B (zh) 2017-11-23 2018-11-22 新型干粉吸入装置

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CN201711177647.1A Pending CN109821118A (zh) 2017-11-23 2017-11-23 新型肺部药物输送系统
CN202210022797.XA Active CN114452496B (zh) 2017-11-23 2018-11-22 新型干粉吸入装置

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US (1) US11931506B2 (zh)
EP (1) EP3714928A4 (zh)
JP (1) JP7209715B2 (zh)
KR (1) KR20200090802A (zh)
CN (3) CN109821118A (zh)
WO (1) WO2019101135A1 (zh)

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DE102018108958A1 (de) * 2018-04-16 2019-10-17 Emphasys Importadora Exportadora E Distribuidora Ltda. Trockenpulverinhalator
CN111388814A (zh) * 2020-05-22 2020-07-10 苏州新劢德医疗器械科技有限公司 一种粉末吸入器装置
FR3134520B1 (fr) * 2022-04-14 2024-04-19 Aptar France Sas Inhalateur unidose de poudre
CN115814217B (zh) * 2023-02-14 2023-05-12 杭州希溪制药有限公司 一种粉雾剂吸入器械

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US5002048A (en) * 1989-12-12 1991-03-26 Makiej Jr Walter J Inhalation device utilizing two or more aerosol containers
US5901883A (en) * 1995-11-08 1999-05-11 Ing. Erich Pfeiffer Gmbh Dispenser having nozzle insert with passages for discharge of two media
CN1255867A (zh) * 1997-03-14 2000-06-07 阿斯特拉公司 吸入器具
CN1805765A (zh) * 2003-06-16 2006-07-19 格罗宁根大学 干粉吸入器以及干粉的肺吸入方法
CN101443066A (zh) * 2006-05-16 2009-05-27 霍维翁英特股份公司 一种简易吸入器
TWM333904U (en) * 2007-11-27 2008-06-11 Jeng Chwei Entpr Co Ltd Asthma medication inhaler
CN204207070U (zh) * 2014-09-26 2015-03-18 深圳市麦克韦尔科技有限公司 吸入器、雾化组件及雾化芯
WO2016174393A1 (en) * 2015-04-30 2016-11-03 Hovione Technology Limited Powder compartment for high dosage drug delivery
CN204951865U (zh) * 2015-09-19 2016-01-13 王静 一种临床护理用雾化吸入装置
CN106913943A (zh) * 2017-03-23 2017-07-04 英华融泰医疗科技股份有限公司 眼部雾化器
CN106924845A (zh) * 2017-04-17 2017-07-07 苏州新劢德医疗器械科技有限公司 一种干粉吸入器

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JP2021504023A (ja) 2021-02-15
EP3714928A1 (en) 2020-09-30
EP3714928A4 (en) 2021-08-18
KR20200090802A (ko) 2020-07-29
CN114452496A (zh) 2022-05-10
CN114452496B (zh) 2023-05-23
CN111344032B (zh) 2021-12-24
CN109821118A (zh) 2019-05-31
WO2019101135A1 (zh) 2019-05-31
US20200360631A1 (en) 2020-11-19
US11931506B2 (en) 2024-03-19
JP7209715B2 (ja) 2023-01-20

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