CN111329918A - Traditional Chinese medicine composition for treating oral ulcer and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating oral ulcer and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating oral ulcer and a preparation method thereof, wherein the traditional Chinese medicine composition comprises the following raw materials: cortex Phellodendri, Catechu, radix Arnebiae, Concha Ostreae, radix Platycodi, radix Ulmi Pumilae, Alumen, flos Sophorae Immaturus, fructus Gleditsiae Abnormalis, and Borneolum Syntheticum. The invention has the beneficial effects that: the Chinese medicinal composition for treating the dental ulcer is prepared by combining the raw materials, takes the incinerated sophora flower bud and the Chinese honeylocust fruit as monarch medicaments, has the effects of activating blood circulation, relieving pain, stopping bleeding and promoting tissue regeneration, supplements the rest raw materials to achieve the effects of clearing away heart-fire, nourishing yin, clearing heat, invigorating spleen, eliminating dampness, promoting the secretion of saliva or body fluid, removing blood stasis, promoting tissue regeneration, clearing liver, purging pathogenic fire, soothing liver, regulating qi, tonifying qi and nourishing blood, can promote self-healing of the dental ulcer, has short treatment course and no toxic or side effect, and does not relapse after healing.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating oral ulcer and a preparation method thereof.
Background
The oral ulcer is commonly called as canker sore, is a common ulcerative injury disease occurring in oral mucosa, and is mostly seen in the inner side of lips, tongue abdomen, buccal mucosa, vestibular sulcus, soft palate and other parts, the mucosa of the parts lacks of cutinization layer or is poor in keratinization, and the tongue ulcer refers to oral ulcer occurring in the tongue and tongue abdomen parts. The oral ulcer is mainly caused by trauma, diet, genetic factors and mental factors, such as tobacco and alcohol incoordination, damp-heat evil, internal heat invasion and fire transformation, emotional depression, long-term fire transformation, yin deficiency, yin impairment due to fever or sleep deficiency, irregular diet, acridity and coldness, and body weakness and immunity decline due to long-term fatigue. Severe pain during oral ulcer attack, obvious local pain, serious patients affecting diet and speaking, causing great inconvenience to daily life, and causing general symptoms such as halitosis, chronic pharyngitis, constipation, headache, dizziness, nausea, debilitation, dysphoria, fever, lymphadenectasis, etc.; and recurrent attacks, even long-term and non-recovery phenomena, may occur.
The clinical treatment of the disease is various, and the clinical treatment of the disease comprises antibiotics, hormones, analgesics, corrosive drugs, digestive system drugs, biological products, vitamin drugs, various traditional Chinese medicines, a large amount of folk prescriptions, secret prescriptions and the like. Although these drugs have a certain therapeutic effect, they all have many disadvantages. The long-term use of broad-spectrum antibiotics and chemically synthesized antibacterial drugs also destroys the microbial balance of the oral cavity, the use time of hormone drugs should be controlled within 1 week as much as possible, the inhibition of hypothalamus-pituitary-adrenal axis can be caused if the use time is too long, the recurrence caused by local immunity can be further reduced, the local irritation of corrosive drugs is strong, the vomiting reflex of patients can be inhibited, and the food and water are prevented from entering the respiratory tract by mistake during the eating, so the use is very inconvenient. Although biological products such as basic fibroblast growth factor preparations have definite curative effects on promoting ulcer healing and relieving pain, the biological products are the first choice medicines acknowledged by the oral medical field at present, but the biological products are expensive, need to be refrigerated at low temperature, and are inconvenient for patients to carry, use and store by themselves.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine composition for treating oral ulcer, which has the advantages of simple treatment method, low cost, no side effect, complete cure and prevention of repeated attack, and a preparation method thereof.
In order to achieve the purpose, the invention adopts the following technical scheme:
a traditional Chinese medicine composition for treating oral ulcer comprises the following raw materials in parts by weight: 30-50 parts of phellodendron, 10-20 parts of catechu, 50-80 parts of lithospermum, 20-40 parts of oyster, 40-50 parts of platycodon grandiflorum, 50-60 parts of elm root, 10-20 parts of alum, 160 parts of sophora flower bud, 160 parts of saponin and 15-20 parts of borneol.
Further, the traditional Chinese medicine composition for treating oral ulcer comprises the following raw materials in parts by weight: 35-45 parts of phellodendron, 12-18 parts of acacia catechu, 55-75 parts of lithospermum, 25-35 parts of oyster, 43-48 parts of platycodon grandiflorum, 53-58 parts of elm root, 12-18 parts of alum, 155 parts of sophora flower bud, 155 parts of gleditsia sinensis, and 16-18 parts of borneol.
Further, the traditional Chinese medicine composition for treating oral ulcer comprises the following raw materials in parts by weight: 40 parts of phellodendron, 15 parts of cutch, 65 parts of lithospermum, 30 parts of oyster, 45 parts of platycodon grandiflorum, 55 parts of elm root, 15 parts of alum, 140 parts of sophora flower bud, 140 parts of Chinese honeylocust fruit and 17 parts of borneol.
Further, the traditional Chinese medicine composition for treating dental ulcer further comprises sesame oil, and preferably, the sesame oil is cooked sesame oil.
Cortex Phellodendri is the dry bark of phellodendron chinense of Rutaceae, is bitter and cold in taste, has effects of clearing heat and eliminating dampness, purging pathogenic fire and removing dampness, and is often used for treating damp-heat dysentery, leukorrhagia pudendal pruritus, bone steaming and fatigue heat, night sweat, etc.
Catechu, school name: acacia catechu is a plant of Acacia in Leguminosae, is bitter in taste and slightly cold in nature, has the effects of astringing dampness, promoting granulation and healing sore, and is often used for treating symptoms such as unhealed ulcer, eczema, traumatic injury, traumatic hemorrhage and the like.
Gromwell (with the scientific name of Lithospermum erythrorhizon Sieb. et Zucc.) is a perennial herb of Lithospermum in Boraginaceae, has bitter and cold taste, has effects of cooling blood, promoting blood circulation, clearing heat and detoxicating, and is commonly used for treating symptoms such as warm heat macula, damp-heat jaundice, purpura, vomit, epistaxis, hematuria, stranguria with turbid urine, constipation due to heat accumulation, burn, eczema, erysipelas, carbuncle and the like.
Oyster, also called fresh oyster, is the most abundant zinc-containing food in all foods, is rich in protein zinc, and is a good zinc-supplementing food. Salty and slightly cold, and has the effects of calming liver wind and nourishing yin.
Platycodon grandiflorum, namely, burl flower, small bell flower and monkshood flower is a perennial herb, has the effects of ventilating the lung, relieving sore throat, eliminating phlegm and discharging pus, and is commonly used for treating symptoms such as cough with excessive phlegm, chest distress, sore throat, hoarseness, pulmonary abscess, pus discharge, pyocutaneous disease with ulceration and the like.
The elm root, sweet in nature and taste, is nontoxic, and has the effects of inducing diuresis to alleviate edema, treating stranguria, promoting defecation and urination, removing damp-heat and dredging channels and collaterals. It can be used for treating urinary obstruction, stranguria with turbid urine, edema, carbuncle, cellulitis, carbuncle, erysipelas, and scabies.
Alum is crystal extracted from mineral alunite. The main chemical component is aluminum potassium sulfate dodecahydrate. Mineral Chinese medicine, sour and astringent in nature and taste, has antibacterial and astringent effects, and can detoxify, kill parasites, eliminate dampness and relieve itching when being externally used; internal use can stop bleeding, check diarrhea and resolve phlegm.
Sophora japonica is broadly a dried bud and flower of Sophora japonica L (Leguminosae). It is slightly cold in nature and bitter in taste, has effects of cooling blood, stopping bleeding, clearing liver-fire, and is commonly used for hematochezia, hemorrhoidal bleeding, bloody dysentery, metrorrhagia and metrostaxis, hematemesis, epistaxis, liver heat with reddish eye, headache, vertigo, etc.
Chinese honeylocust, also known as Chinese honeylocust tree, is one of the unique sappan of family Caesalpiniaceae, genus Gleditsia of China, has the effects of detumescence, detoxification, pus discharge and disinsection, is commonly used for treating the symptoms such as early carbuncle and cellulitis or no ulceration of pus, can be added into traditional Chinese medicines, and is mostly used for treating acne, hordeolum, activating blood and softening hard masses and dissipating stagnation.
Borneol, also called borneol, borneol and the like, is a crystal obtained by extracting resin and volatile oil processed products of borneol family, and is almost pure dextroborneol. It has fragrant smell and cool taste. The borneol has the functions of bacteriostasis and anti-inflammation, is easy to absorb in mucous membrane and subcutaneous tissue, has light stimulation to sensory nerve when being applied to local parts, has the functions of relieving pain and mild antisepsis, and can be used for treating neuralgia.
The preparation method of the traditional Chinese medicine composition for treating oral ulcer comprises the following steps:
(1) drying flos Sophorae Immaturus and fructus Gleditsiae Abnormalis, and burning to obtain flos Sophorae Immaturus ash and soap leftover ash;
(2) grinding flos Sophorae Immaturus ash and fructus Gleditsiae Abnormalis ash respectively to obtain flos Sophorae Immaturus ash and fructus Gleditsiae Abnormalis ash;
(3) pulverizing the raw materials except flos Sophorae Immaturus and fructus Gleditsiae Abnormalis respectively to obtain raw material powder;
(4) the sophora flower bud fine ash, the saponin fine ash and the raw material powder are mixed and stirred uniformly to obtain the traditional Chinese medicine composition for treating the dental ulcer.
The sophora flower bud and the Chinese honeylocust fruit which are burnt into ash can achieve the effects of stopping bleeding, sterilizing and disinfecting, and the sophora flower bud and the Chinese honeylocust fruit which are burnt into ash can promote the regeneration of skin because most of dental ulcers can have rotten bleeding symptoms, thereby achieving the good effects of stopping bleeding, sterilizing and promoting tissue regeneration.
Further, in the step (1), the sophora flower bud and the Chinese honeylocust fruit are dried at the temperature of 50-100 ℃ until the water content is 6% -8%. Before burning, drying flos Sophorae Immaturus and fructus Gleditsiae Abnormalis as far as possible, and ensuring thorough burning.
Preferably, in the step (1), the sophora flower bud and the Chinese honeylocust fruit are dried at 80 ℃ until the water content is 6%.
Further, in the step (2), the fineness of the fine ash of the sophora flower bud and the fineness of the fine ash of the Chinese honeylocust fruit are both more than 90 meshes. The traditional Chinese medicine composition for treating the ulcer is externally applied to the affected part, so that the traditional Chinese medicine composition is ensured to be thin enough and is beneficial to the absorption of the medicine.
Further, in the step (3), the drying is natural drying at a temperature of 25-30 ℃.
Further, in the step (3), the fineness of the obtained raw material powder is 90 meshes or more.
The use method of the traditional Chinese medicine composition for treating oral ulcer comprises the following steps: the powder raw materials of the traditional Chinese medicine composition are mixed with sesame oil and stirred uniformly, and the mixture is applied to the affected part uniformly, 3 to 4 times a day.
The invention has the beneficial effects that: the Chinese medicinal composition for treating the dental ulcer is prepared by combining the raw materials, takes the incinerated sophora flower bud and the Chinese honeylocust fruit as monarch medicaments, has the effects of activating blood circulation, relieving pain, stopping bleeding and promoting tissue regeneration, supplements the rest raw materials to achieve the effects of clearing away heart-fire, nourishing yin, clearing heat, invigorating spleen, eliminating dampness, promoting the secretion of saliva or body fluid, removing blood stasis, promoting tissue regeneration, clearing liver, purging pathogenic fire, soothing liver, regulating qi, tonifying qi and nourishing blood, can promote self-healing of the dental ulcer, has short treatment course and no toxic or side effect, and does not relapse after healing.
The traditional Chinese medicine composition for treating the dental ulcer has good curative effect on the dental ulcer caused by trauma factors, diet factors, genetic factors, mental factors, such as tobacco and wine stagnation, damp-heat evil, internal heat, fire transformation, emotional depression, yin deficiency, fever yin impairment, insufficient sleep, body weakness and body immunity reduction.
The traditional Chinese medicine composition for treating oral ulcer is simple in preparation method, easy to operate and suitable for large-scale production.
Detailed Description
Example 1
A traditional Chinese medicine composition for treating oral ulcer comprises the following raw materials in parts by weight: 30g of phellodendron, 10g of cutch, 50g of lithospermum, 20g of oyster, 40g of platycodon grandiflorum, 50g of elm root, 10g of alum, 120g of sophora flower bud, 120g of Chinese honeylocust fruit and 15g of borneol.
The preparation method of the traditional Chinese medicine composition for treating oral ulcer comprises the following steps:
(1) drying flos Sophorae Immaturus and fructus Gleditsiae Abnormalis at 50 deg.C until water content is 6%, and burning to obtain flos Sophorae Immaturus ash and soap leftover ash;
(2) grinding flos Sophorae Immaturus ash and fructus Gleditsiae Abnormalis ash respectively to obtain fine ash of flos Sophorae Immaturus and fructus Gleditsiae Abnormalis with fineness of above 90 meshes;
(3) naturally drying the raw materials except flos Sophorae Immaturus and fructus Gleditsiae Abnormalis at 25 deg.C, and pulverizing respectively to obtain 100 mesh raw material powder;
(4) the sophora flower bud fine ash, the saponin fine ash and the raw material powder are mixed and stirred uniformly to obtain the traditional Chinese medicine composition for treating the dental ulcer.
Example 2
A traditional Chinese medicine composition for treating oral ulcer comprises the following raw materials in parts by weight: 35g of phellodendron, 12g of acacia catechu, 55g of lithospermum, 25g of oyster, 43g of platycodon grandiflorum, 53g of elm root, 12g of alum, 125g of sophora flower bud, 125g of Chinese honeylocust fruit and 16g of borneol.
The preparation method of the traditional Chinese medicine composition for treating oral ulcer comprises the following steps:
(1) drying flos Sophorae Immaturus and fructus Gleditsiae Abnormalis at 70 deg.C until water content is 6%, and burning to obtain flos Sophorae Immaturus ash and soap leftover ash;
(2) grinding flos Sophorae Immaturus ash and fructus Gleditsiae Abnormalis ash respectively to obtain fine ash of flos Sophorae Immaturus and fructus Gleditsiae Abnormalis with fineness of above 90 meshes;
(3) naturally drying the raw materials except flos Sophorae Immaturus and fructus Gleditsiae Abnormalis at 28 deg.C, and pulverizing respectively to obtain 100 mesh raw material powder;
(4) the sophora flower bud fine ash, the saponin fine ash and the raw material powder are mixed and stirred uniformly to obtain the traditional Chinese medicine composition for treating the dental ulcer.
Example 3
A traditional Chinese medicine composition for treating oral ulcer comprises the following raw materials in parts by weight: 40g of phellodendron bark, 15g of catechu, 65g of lithospermum, 30g of oyster, 45g of platycodon grandiflorum, 55g of elm root, 15g of alum, 140g of sophora flower bud, 140g of Chinese honeylocust fruit and 17g of borneol.
The preparation method of the traditional Chinese medicine composition for treating oral ulcer comprises the following steps:
(1) drying flos Sophorae Immaturus and fructus Gleditsiae Abnormalis at 80 deg.C until water content is 7%, and burning to obtain flos Sophorae Immaturus ash and soap leftover ash;
(2) grinding flos Sophorae Immaturus ash and fructus Gleditsiae Abnormalis ash respectively to obtain fine ash of flos Sophorae Immaturus and fructus Gleditsiae Abnormalis with fineness of above 90 meshes;
(3) naturally drying the raw materials except flos Sophorae Immaturus and fructus Gleditsiae Abnormalis at 28 deg.C, and pulverizing respectively to obtain 100 mesh raw material powder;
(4) the sophora flower bud fine ash, the saponin fine ash and the raw material powder are mixed and stirred uniformly to obtain the traditional Chinese medicine composition for treating the dental ulcer.
Example 4
A traditional Chinese medicine composition for treating oral ulcer comprises the following raw materials in parts by weight: 45g of phellodendron bark, 18g of catechu, 75g of lithospermum, 35g of oyster, 48g of platycodon grandiflorum, 58g of elm root, 18g of alum, 155g of sophora flower bud, 155g of Chinese honeylocust fruit and 18g of borneol.
The preparation method of the traditional Chinese medicine composition for treating oral ulcer comprises the following steps:
(1) drying flos Sophorae Immaturus and fructus Gleditsiae Abnormalis at 90 deg.C until water content is 6%, and burning to obtain flos Sophorae Immaturus ash and soap leftover ash;
(2) grinding flos Sophorae Immaturus ash and fructus Gleditsiae Abnormalis ash respectively to obtain fine ash of flos Sophorae Immaturus and fructus Gleditsiae Abnormalis with fineness of above 90 meshes;
(3) naturally drying the raw materials except flos Sophorae Immaturus and fructus Gleditsiae Abnormalis at 26 deg.C, and pulverizing respectively to obtain 100 mesh raw material powder;
(4) the sophora flower bud fine ash, the saponin fine ash and the raw material powder are mixed and stirred uniformly to obtain the traditional Chinese medicine composition for treating the dental ulcer.
Example 5
A traditional Chinese medicine composition for treating oral ulcer comprises the following raw materials in parts by weight: 50g of phellodendron bark, 20g of catechu, 80g of lithospermum, 40g of oyster, 50g of platycodon grandiflorum, 60g of elm root, 20g of alum, 160g of sophora flower bud, 160g of Chinese honeylocust fruit and 20g of borneol.
The preparation method of the traditional Chinese medicine composition for treating oral ulcer comprises the following steps:
(1) drying flos Sophorae Immaturus and fructus Gleditsiae Abnormalis at 100 deg.C until water content is 8%, and burning to obtain flos Sophorae Immaturus ash and soap leftover ash;
(2) grinding flos Sophorae Immaturus ash and fructus Gleditsiae Abnormalis ash respectively to obtain fine ash of flos Sophorae Immaturus and fructus Gleditsiae Abnormalis with fineness of above 90 meshes;
(3) naturally drying the raw materials except flos Sophorae Immaturus and fructus Gleditsiae Abnormalis at 30 deg.C, and pulverizing respectively to obtain 100 mesh raw material powder;
(4) the sophora flower bud fine ash, the saponin fine ash and the raw material powder are mixed and stirred uniformly to obtain the traditional Chinese medicine composition for treating the dental ulcer.
Comparative example 1
Comparative example 1 the traditional Chinese medicine composition for treating oral ulcer, which uses the raw materials without platycodon grandiflorum, and the rest raw materials, the weight parts and the preparation method are the same as those in example 3.
Comparative example 2
Comparative example 2A traditional Chinese medicine composition for treating oral ulcer, which is prepared from the raw materials not including Catechu, and the rest raw materials, the parts by weight and the preparation method are the same as those in example 3.
Comparative example 3
Comparative example 3A traditional Chinese medicine composition for treating oral ulcer, which is prepared from the same raw materials and in the same weight parts as in example 3, is different from example 3 in that sophora flower bud and Chinese honey locust are dried and directly pulverized without being burned.
240 volunteers of patients with oral ulcer are selected, evenly divided into 8 groups, test groups 1-5 groups and control groups 1-3 groups, wherein the test groups 1-5 groups are respectively correspondingly coated with the traditional Chinese medicine composition for treating oral ulcer disclosed by the embodiments 1-5 of the invention for three times every day; the control groups 1-3 are respectively correspondingly coated with the traditional Chinese medicine composition for treating dental ulcer in the comparative examples 1-3, and the traditional Chinese medicine composition is coated three times per day; after three days of continuous treatment, the condition of each group of volunteers was observed and recorded, and the recurrence was observed and recorded within one month, and the test results are shown in table 1:
TABLE 1 test results
Remarking: and (3) curing: the oral ulcer wound disappears;
the method has the following advantages: the oral ulcer wound surface becomes small, and the red swelling around the wound surface is reduced;
and (4) invalidation: the oral ulcer wound surface is unchanged or more serious, and the wound surface is whitish;
the effective rate is × 100% of effective/total people;
recurrence rate%: the percentage of people who recurred per group to the total number per group.
As can be seen from table 1: the traditional Chinese medicine composition for treating oral ulcer has a better treatment effect on oral ulcer, the cure rate reaches 93%, no invalid symptom exists, and the recurrence rate is lower than 5%; compared with the traditional Chinese medicine composition disclosed by the invention, the contrast group 1 is free of platycodon grandiflorum in raw materials, the cure rate is 83%, and the recurrence rate reaches 8%, the contrast group 2 is free of catechu in raw materials, the cure rate is 81%, and the recurrence rate is 9%, compared with the traditional Chinese medicine composition disclosed by the invention, the contrast group 3 is directly pulverized without burning raw materials of sophora flower bud and Chinese honeylocust fruit, the cure rate is 82%, and the recurrence rate is 8%; the traditional Chinese medicine composition for treating the oral ulcer is superior to the traditional Chinese medicine composition for treating the oral ulcer in comparative examples 1-3 in the treatment effect on the oral ulcer, namely, the traditional Chinese medicine composition for treating the oral ulcer achieves the effect that all raw materials supplement each other and achieve the effect through synergistic effect; in addition, the sophora flower bud and the Chinese honeylocust fruit are directly used under the condition of not burning, and the ideal effect cannot be achieved in the traditional Chinese medicine composition.
Claims (10)
1. The traditional Chinese medicine composition for treating oral ulcer is characterized by comprising the following raw materials in parts by weight: 30-50 parts of phellodendron, 10-20 parts of catechu, 50-80 parts of lithospermum, 20-40 parts of oyster, 40-50 parts of platycodon grandiflorum, 50-60 parts of elm root, 10-20 parts of alum, 160 parts of sophora flower bud, 160 parts of saponin and 15-20 parts of borneol.
2. The traditional Chinese medicine composition for treating oral ulcer according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 35-45 parts of phellodendron, 12-18 parts of acacia catechu, 55-75 parts of lithospermum, 25-35 parts of oyster, 43-48 parts of platycodon grandiflorum, 53-58 parts of elm root, 12-18 parts of alum, 155 parts of sophora flower bud, 155 parts of gleditsia sinensis, and 16-18 parts of borneol.
3. The traditional Chinese medicine composition for treating oral ulcer according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 40 parts of phellodendron, 15 parts of cutch, 65 parts of lithospermum, 30 parts of oyster, 45 parts of platycodon grandiflorum, 55 parts of elm root, 15 parts of alum, 140 parts of sophora flower bud, 140 parts of Chinese honeylocust fruit and 17 parts of borneol.
4. The traditional Chinese medicine composition for treating oral ulcer according to claim 1, further comprising sesame oil, preferably, the sesame oil is cooked sesame oil.
5. The method for preparing a Chinese medicinal composition for treating oral ulcer as claimed in any one of claims 1 to 4, which comprises the following steps:
(1) drying flos Sophorae Immaturus and fructus Gleditsiae Abnormalis, and burning to obtain flos Sophorae Immaturus ash and soap leftover ash;
(2) grinding flos Sophorae Immaturus ash and fructus Gleditsiae Abnormalis ash respectively to obtain flos Sophorae Immaturus ash and fructus Gleditsiae Abnormalis ash;
(3) drying and respectively pulverizing the raw materials except flos Sophorae Immaturus and fructus Gleditsiae Abnormalis to obtain raw material powder;
(4) the sophora flower bud fine ash, the saponin fine ash and the raw material powder are mixed and stirred uniformly to obtain the traditional Chinese medicine composition for treating the dental ulcer.
6. The method for preparing a Chinese medicinal composition for treating oral ulcer according to claim 5, wherein in the step (1), the pagodatree flower bud and the Chinese honeylocust fruit are dried at 50-100 ℃ until the water content is 6% -8%.
7. The method for preparing a Chinese medicinal composition for treating oral ulcer according to claim 5, wherein in the step (1), the pagodatree flower bud and the Chinese honeylocust fruit are dried at 80 ℃ until the water content is 6%.
8. The method for preparing a Chinese medicinal composition for treating oral ulcer according to claim 5, wherein in step (2), the fineness of the fine ash of sophora flower bud and the fine ash of Chinese honeylocust fruit are both more than 90 meshes.
9. The method for preparing a Chinese medicinal composition for treating oral ulcer according to claim 5, wherein in the step (3), the drying is natural drying at a temperature of 25-30 ℃.
10. The preparation method of the traditional Chinese medicine composition for treating oral ulcer according to claim 5, wherein in the step (3), the fineness of the obtained raw material powder is more than 90 meshes.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102283932A (en) * | 2011-09-08 | 2011-12-21 | 刘景君 | Chinese patent drug for treating canker sore by external application |
| CN108635478A (en) * | 2018-06-22 | 2018-10-12 | 孙鲲鹏 | It is a kind of to treat canker sore, pharyngitis, the Chinese medicine composition of tonsillitis and preparation method |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102283932A (en) * | 2011-09-08 | 2011-12-21 | 刘景君 | Chinese patent drug for treating canker sore by external application |
| CN108635478A (en) * | 2018-06-22 | 2018-10-12 | 孙鲲鹏 | It is a kind of to treat canker sore, pharyngitis, the Chinese medicine composition of tonsillitis and preparation method |
Non-Patent Citations (1)
| Title |
|---|
| 郑学彬等: "自拟清热消疡经验方辨治脾胃湿热证复发性口腔溃疡62例 ", 《环球中医药》 * |
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Application publication date: 20200626 |