CN111329784A - Wrinkle-removing essence cream and preparation method thereof - Google Patents
Wrinkle-removing essence cream and preparation method thereof Download PDFInfo
- Publication number
- CN111329784A CN111329784A CN202010256561.3A CN202010256561A CN111329784A CN 111329784 A CN111329784 A CN 111329784A CN 202010256561 A CN202010256561 A CN 202010256561A CN 111329784 A CN111329784 A CN 111329784A
- Authority
- CN
- China
- Prior art keywords
- phase
- mixture
- wrinkle
- parts
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000006071 cream Substances 0.000 title claims abstract description 72
- 238000002360 preparation method Methods 0.000 title claims description 18
- 239000002994 raw material Substances 0.000 claims abstract description 49
- 238000002156 mixing Methods 0.000 claims abstract description 24
- 102000008186 Collagen Human genes 0.000 claims abstract description 22
- 108010035532 Collagen Proteins 0.000 claims abstract description 22
- 229920001436 collagen Polymers 0.000 claims abstract description 22
- 238000000034 method Methods 0.000 claims abstract description 7
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 98
- 239000000203 mixture Substances 0.000 claims description 92
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 54
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims description 40
- 235000011187 glycerol Nutrition 0.000 claims description 35
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 27
- 229920002125 Sokalan® Polymers 0.000 claims description 27
- 229960001631 carbomer Drugs 0.000 claims description 27
- 238000003756 stirring Methods 0.000 claims description 20
- BYUQATUKPXLFLZ-UIOOFZCWSA-N CCCCCCCCCCCCCCCC(=O)NCC(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(O)=O)CC1=CN=CN1 Chemical compound CCCCCCCCCCCCCCCC(=O)NCC(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(O)=O)CC1=CN=CN1 BYUQATUKPXLFLZ-UIOOFZCWSA-N 0.000 claims description 19
- 229940093441 palmitoyl oligopeptide Drugs 0.000 claims description 19
- IHRKJQSLKLYWBQ-QKDODKLFSA-N (2s)-2-[[(2s)-1-[(2s)-5-amino-2-[[2-(hexadecanoylamino)acetyl]amino]-5-oxopentanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid Chemical compound CCCCCCCCCCCCCCCC(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(O)=O IHRKJQSLKLYWBQ-QKDODKLFSA-N 0.000 claims description 18
- 229940015975 1,2-hexanediol Drugs 0.000 claims description 18
- SAVLIIGUQOSOEP-UHFFFAOYSA-N N-octanoylglycine Chemical compound CCCCCCCC(=O)NCC(O)=O SAVLIIGUQOSOEP-UHFFFAOYSA-N 0.000 claims description 18
- FHKSXSQHXQEMOK-UHFFFAOYSA-N hexane-1,2-diol Chemical compound CCCCC(O)CO FHKSXSQHXQEMOK-UHFFFAOYSA-N 0.000 claims description 18
- 229940094946 palmitoyl tetrapeptide-7 Drugs 0.000 claims description 18
- 229920001213 Polysorbate 20 Polymers 0.000 claims description 16
- 239000002253 acid Substances 0.000 claims description 16
- ACCCMOQWYVYDOT-UHFFFAOYSA-N hexane-1,1-diol Chemical compound CCCCCC(O)O ACCCMOQWYVYDOT-UHFFFAOYSA-N 0.000 claims description 16
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 claims description 16
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 claims description 16
- 229940068977 polysorbate 20 Drugs 0.000 claims description 16
- 125000002801 octanoyl group Chemical group C(CCCCCCC)(=O)* 0.000 claims description 13
- -1 polydimethylsiloxane Polymers 0.000 claims description 13
- 229920002385 Sodium hyaluronate Polymers 0.000 claims description 12
- 229920006037 cross link polymer Polymers 0.000 claims description 12
- 239000004205 dimethyl polysiloxane Substances 0.000 claims description 12
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims description 12
- 229940010747 sodium hyaluronate Drugs 0.000 claims description 12
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims description 12
- OMIGHNLMNHATMP-UHFFFAOYSA-N 2-hydroxyethyl prop-2-enoate Chemical compound OCCOC(=O)C=C OMIGHNLMNHATMP-UHFFFAOYSA-N 0.000 claims description 10
- 239000004475 Arginine Substances 0.000 claims description 10
- QRYRORQUOLYVBU-VBKZILBWSA-N Carnosic acid Natural products CC([C@@H]1CC2)(C)CCC[C@]1(C(O)=O)C1=C2C=C(C(C)C)C(O)=C1O QRYRORQUOLYVBU-VBKZILBWSA-N 0.000 claims description 10
- 108010087806 Carnosine Proteins 0.000 claims description 10
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 10
- CQOVPNPJLQNMDC-UHFFFAOYSA-N N-beta-alanyl-L-histidine Natural products NCCC(=O)NC(C(O)=O)CC1=CN=CN1 CQOVPNPJLQNMDC-UHFFFAOYSA-N 0.000 claims description 10
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims description 10
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims description 10
- 239000004202 carbamide Substances 0.000 claims description 10
- CQOVPNPJLQNMDC-ZETCQYMHSA-N carnosine Chemical compound [NH3+]CCC(=O)N[C@H](C([O-])=O)CC1=CNC=N1 CQOVPNPJLQNMDC-ZETCQYMHSA-N 0.000 claims description 10
- 229940044199 carnosine Drugs 0.000 claims description 10
- 229920001577 copolymer Polymers 0.000 claims description 10
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 claims description 10
- 239000000600 sorbitol Substances 0.000 claims description 10
- LADGBHLMCUINGV-UHFFFAOYSA-N tricaprin Chemical compound CCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCC)COC(=O)CCCCCCCCC LADGBHLMCUINGV-UHFFFAOYSA-N 0.000 claims description 10
- 239000002245 particle Substances 0.000 claims description 8
- 229940104256 sodium taurate Drugs 0.000 claims description 8
- 238000001914 filtration Methods 0.000 claims description 6
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 claims description 5
- RJZNPROJTJSYLC-LLINQDLYSA-N (4s)-4-acetamido-5-[[(2s)-1-[[(2s)-1-[[(2s)-5-amino-1-[[(2s)-1-[[(2s)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-car Chemical compound OC(=O)CC[C@H](NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O RJZNPROJTJSYLC-LLINQDLYSA-N 0.000 claims description 5
- 238000001816 cooling Methods 0.000 claims description 5
- 238000007872 degassing Methods 0.000 claims description 5
- 238000010438 heat treatment Methods 0.000 claims description 5
- SVTBMSDMJJWYQN-UHFFFAOYSA-N 2-methylpentane-2,4-diol Chemical compound CC(O)CC(C)(C)O SVTBMSDMJJWYQN-UHFFFAOYSA-N 0.000 claims description 4
- AJLNZWYOJAWBCR-OOPVGHQCSA-N (4s)-4-acetamido-5-[[(2s)-1-[[(2s)-1-[[(2s)-5-amino-1-[[(2s)-1-[[(2s)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-car Chemical compound OC(=O)CC[C@H](NC(C)=O)C(=C)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(N)=O AJLNZWYOJAWBCR-OOPVGHQCSA-N 0.000 claims description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 3
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 claims description 3
- 229940095094 acetyl hexapeptide-8 Drugs 0.000 claims description 3
- 108010006338 acetyl-glutamyl-glutamyl-methionyl-glutaminyl-arginyl-argininamide Proteins 0.000 claims description 3
- 229940051368 capryloyl glycine Drugs 0.000 claims description 3
- 229940051250 hexylene glycol Drugs 0.000 claims description 2
- RGUVUPQQFXCJFC-UHFFFAOYSA-N n-hydroxyoctanamide Chemical compound CCCCCCCC(=O)NO RGUVUPQQFXCJFC-UHFFFAOYSA-N 0.000 claims 2
- 238000000265 homogenisation Methods 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 23
- 239000000047 product Substances 0.000 abstract description 12
- 230000037303 wrinkles Effects 0.000 abstract description 10
- 230000003020 moisturizing effect Effects 0.000 abstract description 8
- 238000010521 absorption reaction Methods 0.000 abstract description 6
- 239000013543 active substance Substances 0.000 abstract description 3
- 201000004624 Dermatitis Diseases 0.000 abstract description 2
- 206010013786 Dry skin Diseases 0.000 abstract description 2
- 230000009286 beneficial effect Effects 0.000 abstract description 2
- 230000037336 dry skin Effects 0.000 abstract description 2
- 239000002932 luster Substances 0.000 abstract description 2
- 235000015097 nutrients Nutrition 0.000 abstract description 2
- 230000008439 repair process Effects 0.000 abstract description 2
- 239000013589 supplement Substances 0.000 abstract description 2
- 239000002344 surface layer Substances 0.000 abstract description 2
- 230000002087 whitening effect Effects 0.000 abstract description 2
- 230000001804 emulsifying effect Effects 0.000 abstract 1
- 230000037368 penetrate the skin Effects 0.000 abstract 1
- 230000000052 comparative effect Effects 0.000 description 14
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 12
- BGNXCDMCOKJUMV-UHFFFAOYSA-N Tert-Butylhydroquinone Chemical compound CC(C)(C)C1=CC(O)=CC=C1O BGNXCDMCOKJUMV-UHFFFAOYSA-N 0.000 description 12
- 235000013870 dimethyl polysiloxane Nutrition 0.000 description 9
- 238000012360 testing method Methods 0.000 description 8
- HHEAADYXPMHMCT-UHFFFAOYSA-N dpph Chemical compound [O-][N+](=O)C1=CC([N+](=O)[O-])=CC([N+]([O-])=O)=C1[N]N(C=1C=CC=CC=1)C1=CC=CC=C1 HHEAADYXPMHMCT-UHFFFAOYSA-N 0.000 description 7
- 230000001815 facial effect Effects 0.000 description 7
- 235000010323 ascorbic acid Nutrition 0.000 description 6
- 229960005070 ascorbic acid Drugs 0.000 description 6
- 239000011668 ascorbic acid Substances 0.000 description 6
- 239000004250 tert-Butylhydroquinone Substances 0.000 description 6
- 235000019281 tert-butylhydroquinone Nutrition 0.000 description 6
- 230000002000 scavenging effect Effects 0.000 description 5
- 239000004744 fabric Substances 0.000 description 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 238000002835 absorbance Methods 0.000 description 3
- 210000004027 cell Anatomy 0.000 description 3
- 238000004140 cleaning Methods 0.000 description 3
- 238000011156 evaluation Methods 0.000 description 3
- 210000003205 muscle Anatomy 0.000 description 3
- 230000003068 static effect Effects 0.000 description 3
- 241000218378 Magnolia Species 0.000 description 2
- 241000220317 Rosa Species 0.000 description 2
- 230000001153 anti-wrinkle effect Effects 0.000 description 2
- 239000003963 antioxidant agent Substances 0.000 description 2
- 230000003078 antioxidant effect Effects 0.000 description 2
- 235000006708 antioxidants Nutrition 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 239000000498 cooling water Substances 0.000 description 2
- 229940008099 dimethicone Drugs 0.000 description 2
- 238000004898 kneading Methods 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 238000003825 pressing Methods 0.000 description 2
- 108090000765 processed proteins & peptides Proteins 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 2
- 238000006467 substitution reaction Methods 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- 108010038807 Oligopeptides Proteins 0.000 description 1
- 102000015636 Oligopeptides Human genes 0.000 description 1
- 239000005862 Whey Substances 0.000 description 1
- 102000007544 Whey Proteins Human genes 0.000 description 1
- 108010046377 Whey Proteins Proteins 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- HEILIGJNYTWOHU-UHFFFAOYSA-N ethanol 2-hydroxybenzoic acid Chemical compound CCO.OC(=O)C1=CC=CC=C1O HEILIGJNYTWOHU-UHFFFAOYSA-N 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 210000001097 facial muscle Anatomy 0.000 description 1
- TUJKJAMUKRIRHC-UHFFFAOYSA-N hydroxyl Chemical compound [OH] TUJKJAMUKRIRHC-UHFFFAOYSA-N 0.000 description 1
- 229910000359 iron(II) sulfate Inorganic materials 0.000 description 1
- 230000002427 irreversible effect Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 239000008213 purified water Substances 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 229960004889 salicylic acid Drugs 0.000 description 1
- 230000036560 skin regeneration Effects 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 239000008223 sterile water Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000001502 supplementing effect Effects 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- SWGJCIMEBVHMTA-UHFFFAOYSA-K trisodium;6-oxido-4-sulfo-5-[(4-sulfonatonaphthalen-1-yl)diazenyl]naphthalene-2-sulfonate Chemical compound [Na+].[Na+].[Na+].C1=CC=C2C(N=NC3=C4C(=CC(=CC4=CC=C3O)S([O-])(=O)=O)S([O-])(=O)=O)=CC=C(S([O-])(=O)=O)C2=C1 SWGJCIMEBVHMTA-UHFFFAOYSA-K 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Cosmetics (AREA)
Abstract
The invention relates to wrinkle-removing essence cream which is prepared by taking a phase A, a phase B and a phase C as raw materials through the methods of mixing, emulsifying, homogenizing and the like for multiple times. The invention has the beneficial effects that: the wrinkle-removing essence cream disclosed by the invention can deeply penetrate the skin surface layer, the transdermal efficiency of macromolecular components is effectively improved, the absorption rate of active nutrient components is enhanced, the wrinkle-removing effect is better, and the prepared finished product has good wrinkle-removing, moisturizing and skin-tendering effects, can effectively remove free radicals, prevent oxidized cells, repair damaged cells and timely supplement collagen and active substances; the skin care product can keep skin vitality, recover skin luster, can permanently remove wrinkles, can effectively improve the problems of dry skin, tightness and fine lines, can not cause skin allergy, and has good skin whitening and moisturizing effects.
Description
Technical Field
The invention belongs to the technical field of cosmetics, and particularly relates to wrinkle-removing essence cream and a preparation method thereof.
Background
Wrinkles are formed when the skin is affected by the external environment or due to repeated movement and traction of facial muscles, and form free radicals which destroy collagen, active substances, oxidized cells and the like in normal cell membrane tissues, and comprise three forms of fine lines, dynamic lines and static lines. The fine lines are also called dry lines, mainly because of the lack of water in the local skin and the movement of small muscles leads to the lines of tiny wrinkles. Dynamic texture is the texture of the face that is locally formed as a result of the pulling of large muscles while performing certain actions, such as laughing, raising the head, opening the eyes, and bletting the mouth. The static veins are like paper folding, and the paper at the same place is folded repeatedly, so that obvious wrinkles appear on the paper at the place, which is the principle of the formation of the static veins, and irreversible creases are generated locally due to long-term repeated muscle movement.
Many wrinkle-removing products are available in the market, but most products have unsatisfactory wrinkle-removing effect.
In view of this, this patent is filed.
Disclosure of Invention
In order to solve the problems in the prior art, the invention provides the wrinkle-removing essence cream and the preparation method thereof.
The invention aims to provide a wrinkle-removing essence cream.
The invention further aims to provide a preparation method of the wrinkle-removing essence cream.
According to the specific embodiment of the invention, the wrinkle-removing essence cream is prepared from a phase A, a phase B and a phase C, wherein the phase A, the phase B and the phase C comprise the following raw materials:
phase A: water; urea; butanediol; sorbitol; sodium hyaluronate; carbomer;
phase B: a polydimethylsiloxane cross-linked polymer; caprylic/capric triglyceride; hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymers;
and C phase: a mixture of soluble collagen, hexylene glycol, glycerol and water; a mixture of glycerol, water, butylene glycol, carbomer, polysorbate-20, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-7; a mixture of butylene glycol, 1, 2-hexanediol, capryloyl glycine, and capryloyl hydroxamic acid; acetyl hexapeptide-8; carnosine; arginine; and (4) essence.
The wrinkle-removing essence cream is prepared from a phase A, a phase B and a phase C, wherein the phase A, the phase B and the phase C comprise the following raw materials in parts by weight:
phase A: 60-68 parts of water; 4-8 parts of urea; 4-6 parts of butanediol; 4-6 parts of sorbitol; 0.05-0.15 part of sodium hyaluronate; 0.03-0.07 part of carbomer;
phase B: 6-10 parts of polydimethylsiloxane cross-linked polymer; 2-4 parts of caprylic/capric triglyceride; 1-3 parts of hydroxyethyl acrylate/acryloyl dimethyl sodium taurate copolymer;
and C phase: 4-6 parts of a mixture of soluble collagen, hexanediol, glycerol and water; 1-3 parts of a mixture of glycerol, water, butanediol, carbomer, polysorbate-20, palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7; 0.5-0.9 part of mixture of butanediol, 1, 2-hexanediol, caprylyl glycine and caprylyl hydroximic acid; acetyl hexapeptide-80.00008-0.00012 portion; 0.05-0.15 part of carnosine; 0.02-0.04 part of arginine; 0.01-0.03 part of essence.
The wrinkle-removing essence cream is prepared from a phase A, a phase B, a phase C and a phase D, wherein the phase A, the phase B, the phase C and the phase D comprise the following raw materials in parts by weight:
phase A: 63 parts of water; 6 parts of urea; 5 parts of butanediol; 5 parts of sorbitol; 0.1 part of sodium hyaluronate; 0.05 part of carbomer;
phase B: 8 parts of polydimethylsiloxane cross-linked polymer; 3 parts of caprylic/capric triglyceride; 2 parts of hydroxyethyl acrylate/acryloyl dimethyl sodium taurate copolymer;
and C phase: 5 parts of a mixture of soluble collagen, hexanediol, glycerol and water; 2 parts of a mixture of glycerol, water, butanediol, carbomer, polysorbate-20, palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7; 0.7 part of a mixture of butanediol, 1, 2-hexanediol, caprylyl glycine and caprylyl hydroximic acid; 80.0001 parts of acetyl hexapeptide; 0.1 part of carnosine; 0.03 part of arginine; 0.02 part of essence.
According to the specific embodiment of the invention, the wrinkle-removing essence cream comprises 53.5% of glycerin, 25% of water, 20% of butanediol, 1% of carbomer, 0.5% of polysorbate-20, 100PPm of palmitoyl tripeptide-1 and 50PPm of palmitoyl tetrapeptide-7 in a mixture of glycerin, water, butanediol, carbomer and 0.5% of palmitoyl tripeptide-1.
According to the embodiment of the invention, the wrinkle-removing essence cream is characterized in that the addition ratio of the butanediol, the 1, 2-hexanediol, the caprylyl glycine and the caprylyl hydroximic acid in the mixture of the butanediol, the 1, 2-hexanediol, the caprylyl glycine and the caprylyl hydroximic acid is 31: 58: 5: 6.
the wrinkle-removing essence cream according to the embodiment of the present invention, wherein the ratio of the addition amounts of the soluble collagen, the hexanediol, the glycerin and the water in the mixture of the soluble collagen, the hexanediol, the glycerin and the water is 0.4: 2: 30: 67.6.
the preparation method of the wrinkle-removing essence cream according to the embodiment of the present invention comprises the steps of:
(1) mixing and homogenizing all the raw materials in the phase A, stirring and heating until all the raw materials in the phase A are completely dissolved until no particles exist, uniformly mixing to form a phase A mixture, and keeping the temperature for later use;
(2) mixing all the raw materials in the phase B, stirring until the raw materials are uniformly mixed to form a phase B mixture, adding the phase B mixture into the phase A mixture obtained in the step (1), stirring and mixing, homogenizing again, and then preserving heat for 15-25 minutes to form a mixture of the phase A and the phase B;
(3) cooling to below 40 deg.C, adding all the raw materials of phase C, and stirring; degassing and filtering to obtain the wrinkle-removing essence cream.
According to the preparation method of the wrinkle-removing essence cream, according to the specific embodiment of the invention, in the step (1), all the raw materials in the phase A are mixed and homogenized, stirred and heated to 83-87 ℃ until all the raw materials in the phase A are completely dissolved to be free of particles.
According to the preparation method of the wrinkle-removing essence cream according to the embodiment of the present invention, preferably, in the step (1), all the raw materials in the phase a are mixed and homogenized, stirred and heated to 85 ℃, until all the raw materials in the phase a are completely dissolved to be free of particles.
According to the preparation method of the wrinkle-removing essence cream, according to the specific embodiment of the invention, in the step (1), the pre-used utensils are firstly cleaned by using sterilized water with the temperature of more than 80 ℃, then washed by using 75% sterilized alcohol, and then all the raw materials in the phase A are mixed and homogenized in the main kettle.
According to the preparation method of the wrinkle-removing essence cream, according to the embodiment of the present invention, in the step (2), the time for re-homogenizing is 5 minutes.
According to the preparation method of the wrinkle-removing essence cream, according to the embodiment of the present invention, in the step (2), the phase a mixture is filtered before being pumped into the phase B.
According to the preparation method of the wrinkle-removing essence cream, the temperature is reduced by cooling water in the step (3).
The wrinkle-removing essence cream prepared by the invention can be used for preparing a facial mask, and specifically comprises the following components: after the facial mask cloth is soaked in the wrinkle-removing essence cream, the facial mask cloth is filled and packaged to prepare a facial mask product.
The water used in the invention is pure water. The essence includes rose essence or magnolia essence.
The use method of the wrinkle-removing essence cream comprises the steps of pressing the wrinkle-removing essence cream on palms, mixing the palms, smearing the mixture on the required parts of a body, kneading the required parts until the required parts are absorbed, and cleaning is not needed after the wrinkle-removing essence cream is used; applied to the desired part 1-3 times per day.
The effects of the raw materials in the wrinkle-removing essence cream are shown in the following table 1:
TABLE 1 Effect of the raw materials
Compared with the prior art, the invention has the following beneficial effects:
(1) the wrinkle-removing essence cream mainly adopts a three-dimensional protection structure consisting of sodium hyaluronate, protein and peptide; the composite peptide consisting of the palmitoyl tripeptide-1 and the palmitoyl tetrapeptide-7 has good effects of promoting skin regeneration and supplementing collagen of the skin, and the acetyl hexapeptide-8, the palmitoyl tripeptide-1 and the palmitoyl tetrapeptide-7 are compounded with other proteins, so that energy can be rapidly provided for the skin, the wrinkle depth, the density and the average volume are reduced, and the roughness is improved.
(2) The wrinkle-removing essence cream disclosed by the invention is smeared on a required part, and then the required part is kneaded, so that the skin surface layer can be deeply penetrated, the transdermal efficiency of macromolecular components is effectively improved, the absorption rate of active nutrient components is enhanced, and the wrinkle-removing effect is better.
(3) The wrinkle-removing essence cream disclosed by the invention is reasonable in raw material matching, and can not be used for a long time, and the prepared finished product has good wrinkle-removing, moisturizing and skin-tendering effects, can effectively remove free radicals, prevent oxidized cells, repair damaged cells, and timely supplement collagen and active substances; the skin care product can keep skin vitality, recover skin luster, can permanently remove wrinkles, can effectively improve the problems of dry skin, tightness and fine lines, can not cause skin allergy, and has good skin whitening and moisturizing effects.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be described in detail below. It is to be understood that the described embodiments are merely exemplary of the invention, and not restrictive of the full scope of the invention. All other embodiments, which can be derived by a person skilled in the art from the examples given herein without any inventive step, are within the scope of the present invention.
The raw materials used in the present invention are all commercially available raw materials.
In some more specific embodiments, the wrinkle-removing essence cream of the present invention is prepared from phases a, B and C:
phase A: 60-68 parts of water; 4-8 parts of urea; 4-6 parts of butanediol; 4-6 parts of sorbitol; 0.05-0.15 part of sodium hyaluronate; 0.03-0.07 part of carbomer;
phase B: 6-10 parts of polydimethylsiloxane cross-linked polymer; 2-4 parts of caprylic/capric triglyceride; 1-3 parts of hydroxyethyl acrylate/acryloyl dimethyl sodium taurate copolymer;
and C phase: 4-6 parts of a mixture of soluble collagen, hexanediol, glycerol and water; 1-3 parts of a mixture of glycerol, water, butanediol, carbomer, polysorbate-20, palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7; 0.5-0.9 part of mixture of butanediol, 1, 2-hexanediol, caprylyl glycine and caprylyl hydroximic acid; acetyl hexapeptide-80.00008-0.00012 portion; 0.05-0.15 part of carnosine; 0.02-0.04 part of arginine; 0.01-0.03 part of essence;
the glycerol, the water, the butanediol, the carbomer, the polysorbate-20, the palmitoyl tripeptide-1 and the palmitoyl tetrapeptide-7 are added into the mixture, wherein the addition amount of the glycerol is 53.5 percent of the weight of the mixture, the addition amount of the water is 25 percent of the weight of the mixture, the addition amount of the butanediol is 20 percent of the weight of the mixture, the addition amount of the carbomer is 1 percent of the weight of the mixture, the addition amount of the polysorbate-20 is 0.5 percent of the weight of the mixture, the addition amount of the palmitoyl tripeptide-1 in the mixture is 100PPm, and the addition amount of the palmitoyl tetrapeptide-7 in the mixture is 50 PPm;
the addition ratio of the butanediol, the 1, 2-hexanediol, the caprylyl glycine and the caprylyl hydroximic acid in the mixture of the butanediol, the 1, 2-hexanediol, the caprylyl glycine and the caprylyl hydroximic acid is 31: 58: 5: 6;
the ratio of the addition amounts of the soluble collagen, the hexanediol, the glycerol and the water in the mixture of the soluble collagen, the hexanediol, the glycerol and the water is 0.4: 2: 30: 67.6.
1 part in the following examples represents 1 g.
Example 1
The embodiment provides a wrinkle-removing essence cream which is prepared from a phase A, a phase B and a phase C:
phase A: 68 parts of water; 4 parts of urea; 6 parts of butanediol; 4 parts of sorbitol; 0.15 part of sodium hyaluronate; 0.03 part of carbomer;
phase B: 10 parts of polydimethylsiloxane cross-linked polymer; 2 parts of caprylic/capric triglyceride; 3 parts of hydroxyethyl acrylate/acryloyl dimethyl sodium taurate copolymer;
and C phase: 4 parts of a mixture of soluble collagen, hexanediol, glycerol and water; 3 parts of a mixture of glycerol, water, butanediol, carbomer, polysorbate-20, palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7; 0.5 part of a mixture of butanediol, 1, 2-hexanediol, capryloyl glycine and capryloyl hydroximic acid; 80.00012 parts of acetyl hexapeptide; 0.05 part of carnosine; 0.04 part of arginine; 0.01 part of rose essence.
The preparation method of the wrinkle-removing essence cream comprises the following steps:
(1) mixing and homogenizing all the raw materials in the phase A, stirring and heating until all the raw materials in the phase A are completely dissolved until no particles exist, uniformly mixing to form a phase A mixture, and keeping the temperature for later use;
(2) mixing all the raw materials in the phase B, stirring until the raw materials are uniformly mixed to form a phase B mixture, adding the phase B mixture into the phase A mixture obtained in the step (1), stirring and mixing, homogenizing again, and then keeping the temperature for 25 minutes to form a mixture of the phase A and the phase B;
(3) cooling to 39 deg.C, adding all the raw materials of phase C, and stirring; degassing and filtering to obtain the wrinkle-removing essence cream.
Example 2
The embodiment provides a wrinkle-removing essence cream which is prepared from a phase A, a phase B and a phase C:
phase A: 60 parts of water; 8 parts of urea; 4 parts of butanediol; 6 parts of sorbitol; 0.05 part of sodium hyaluronate; 0.07 part of carbomer;
phase B: 6 parts of polydimethylsiloxane cross-linked polymer; 4 parts of caprylic/capric triglyceride; 1 part of hydroxyethyl acrylate/acryloyl dimethyl sodium taurate copolymer;
and C phase: 6 parts of a mixture of soluble collagen, hexanediol, glycerol and water; 1 part of a mixture of glycerol, water, butanediol, carbomer, polysorbate-20, palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7; 0.9 part of a mixture of butanediol, 1, 2-hexanediol, caprylyl glycine and caprylyl hydroxamic acid; 80.00008 parts of acetyl hexapeptide; 0.15 part of carnosine; 0.02 part of arginine; 0.03 part of essence. The water is purified water, and the essence is magnolia essence.
The preparation method of the wrinkle-removing essence cream comprises the following steps:
(1) mixing and homogenizing all the raw materials in the phase A, stirring and heating to 87 ℃ until all the raw materials in the phase A are completely dissolved until no particles exist, uniformly mixing to form a phase A mixture, and keeping the temperature for later use;
(2) mixing all the raw materials in the phase B, stirring until the raw materials are uniformly mixed to form a phase B mixture, adding the phase B mixture into the phase A mixture obtained in the step (1), stirring and mixing, homogenizing again, and then preserving heat for 15-25 minutes to form a mixture of the phase A and the phase B; filtering the mixture of the phase A before pumping the mixture of the phase A into the phase B;
(3) cooling to 38 ℃, adding all the raw materials of the phase C, and uniformly stirring; degassing and filtering to obtain the wrinkle-removing essence cream.
Example 3
The embodiment provides a wrinkle-removing essence cream which is prepared from a phase A, a phase B and a phase C:
phase A: 63 parts of water; 6 parts of urea; 5 parts of butanediol; 5 parts of sorbitol; 0.1 part of sodium hyaluronate; 0.05 part of carbomer;
phase B: 8 parts of polydimethylsiloxane cross-linked polymer; 3 parts of caprylic/capric triglyceride; 2 parts of hydroxyethyl acrylate/acryloyl dimethyl sodium taurate copolymer;
and C phase: 5 parts of a mixture of soluble collagen, hexanediol, glycerol and water; 2 parts of a mixture of glycerol, water, butanediol, carbomer, polysorbate-20, palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7; 0.7 part of a mixture of butanediol, 1, 2-hexanediol, caprylyl glycine and caprylyl hydroximic acid; 80.0001 parts of acetyl hexapeptide; 0.1 part of carnosine; 0.03 part of arginine; 0.02 part of essence; the glycerol, the water, the butanediol, the carbomer, the polysorbate-20, the palmitoyl tripeptide-1 and the palmitoyl tetrapeptide-7 are added into the mixture, wherein the addition amount of the glycerol is 53.5 percent of the weight of the mixture, the addition amount of the water is 25 percent of the weight of the mixture, the addition amount of the butanediol is 20 percent of the weight of the mixture, the addition amount of the carbomer is 1 percent of the weight of the mixture, the addition amount of the polysorbate-20 is 0.5 percent of the weight of the mixture, the addition amount of the palmitoyl tripeptide-1 in the mixture is 100PPm, and the addition amount of the palmitoyl tetrapeptide-7 in the mixture is 50 PPm; the addition ratio of the butanediol, the 1, 2-hexanediol, the caprylyl glycine and the caprylyl hydroximic acid in the mixture of the butanediol, the 1, 2-hexanediol, the caprylyl glycine and the caprylyl hydroximic acid is 31: 58: 5: 6; the ratio of the addition amounts of the soluble collagen, the hexanediol, the glycerol and the water in the mixture of the soluble collagen, the hexanediol, the glycerol and the water is 0.4: 2: 30: 67.6.
the preparation method of the wrinkle-removing essence cream comprises the following steps:
(1) cleaning a pre-used tool with sterile water of more than 80 ℃, washing with 75% sterile alcohol, mixing and homogenizing all the raw materials in the phase A in a main kettle, stirring and heating to 85 ℃ until all the raw materials in the phase A are completely dissolved until no particles exist, uniformly mixing to form a phase A mixture, and keeping the temperature for later use;
(2) mixing all the raw materials in the phase B, stirring until the raw materials are uniformly mixed to form a phase B mixture, adding the phase B mixture into the phase A mixture obtained in the step (1) in the main kettle, stirring and mixing, homogenizing for 5 minutes again, and then preserving heat for 20 minutes to form a mixture of the phase A and the phase B;
(3) cooling with cooling water to below 40 deg.C, adding all the raw materials of phase C, and stirring; degassing and filtering to obtain the wrinkle-removing essence cream.
After the facial mask cloth is soaked in the wrinkle-removing essence cream, the soaked facial mask cloth is filled and packaged to prepare a facial mask product.
Comparative example 1
The only difference between this comparative example and example 3 is that no dimethicone crosspolymer was added to the starting material and no dimethicone crosspolymer was added during the preparation.
Comparative example 2
The only difference between this comparative example and example 3 is that no sodium hyaluronate was added to the raw materials and during the preparation process.
The use method of the wrinkle-removing essence cream comprises the steps of pressing the wrinkle-removing essence cream on palms, mixing the palms, smearing the mixture on the required parts of a body, kneading the required parts until the required parts are absorbed, and cleaning is not needed after the wrinkle-removing essence cream is used; applied to the desired part 1-3 times per day.
The wrinkle-removing essence provided by the invention has more active ingredient contents and better wrinkle-removing effect. The follow-up observation shows that the wrinkle removing essence cream provided by the invention is used for 1-2 months, is applied in the morning and at night every day, and has a better wrinkle removing effect.
Effect test
The test evaluates the antioxidant performance of the wrinkle-removing essence cream by investigating the removing effect of the wrinkle-removing essence cream on OH, DPPH and two free radicals.
Test 1 hydroxyl radical (. OH) scavenging Activity
(1) The experimental method comprises the following steps: by means of H2O2With Fe2+The mixing reaction generates OH, salicylic acid is added into the system to capture OH and generate a colored substance which has maximum absorption at the wavelength of 510 nm. The reaction system contains 8.8mmol/L H2O21mL of 9mmol/L FeSO41mL of salicylic acid-ethanol solution with concentration of 9mmol/L and 1mL of wrinkle-removing essence cream solution with concentration of 10%, and distilled water is used as reference. Ascorbic acid and TBHQ were used as control groups, and the absorbance was averaged by repeating the control group 3 times for each concentration.
(2) And (3) test results: see table 2 below:
TABLE 2 detection of scavenging hydroxyl radicals
| Group of | Control rate% |
| Example 1 | 46.38 |
| Example 2 | 45.11 |
| Example 3 | 48.27 |
| Comparative example 1 | 35.17 |
| Comparative example 2 | 20.63 |
| Ascorbic acid | 20.84 |
| TBHQ | 34.24 |
As can be seen from table 2, the ability of removing hydroxyl radicals by using the wrinkle-removing essence cream of the present invention is stronger than that of ascorbic acid and TBHQ, and the wrinkle-removing effect of the product of the comparative example is not as good as the control effect of the wrinkle-removing essence cream of the present invention, which indicates that the raw materials of the wrinkle-removing essence cream of the present invention have a synergistic effect, and the reasonable compatibility of the raw materials gives play to the complementary effect of the raw materials, so that the wrinkle-removing effect can be significantly improved.
Test 2 measurement of DPPH scavenging ability
(1) The test method comprises the following steps: the characteristic purple red absorption peak of the DPPH solution is utilized, and the reduction of the absorbance after the antioxidant or the whey oligopeptide solution is added represents the scavenging capacity of the DPPH solution on free radicals. DPPH is prepared into 0.2mmol/L with methanol, 2mL of the solution is taken to react with 2mL of the wrinkle-removing essence cream solution with the concentration of 10% in a dark room for 30min, each concentration is repeated for 3 times, ascorbic acid and TBHQ are taken as control groups, and the absorbance is measured at the wavelength of 517 nm.
(2) And (3) test results: see table 3 below:
TABLE 3 measurement results of DPPH scavenging ability
| Group of | Control rate% |
| Example 1 | 99.8 |
| Example 2 | 99.7 |
| Example 3 | 99.9 |
| Comparative example 1 | 99.2 |
| Comparative example 2 | 79.5 |
| Ascorbic acid | 8.84 |
| TBHQ | 99.9 |
As can be seen from table 3, the anti-wrinkle essence cream of the present invention has a better DPPH removing ability than ascorbic acid, is the same as TBHQ matrix, and the anti-aging effect of the product of the comparative example is not as good as that of the anti-wrinkle essence cream of the present invention.
Test 3: evaluation of wrinkle-removing Effect
(1) The test method comprises the following steps: 100 volunteers were randomly selected for testing, aged 30-50 years, divided into 5 groups of 20, and the wrinkle-removing essence creams of examples 1-3 and comparative examples 1-2 were used once in the morning and at night while continuously used for one month. The volunteers were allowed to evaluate the products on trial, wherein the total absorption effect was divided into 30 minutes, the total wrinkle-removing effect was divided into 40 minutes, and the total moisturizing effect was divided into 30 minutes. Each volunteer was scored and averaged.
(2) The experimental results are as follows: the results of the trial evaluation are shown in table 4 below:
TABLE 4 trial evaluation results
| Group of | Absorption effect | Wrinkle removing effect | Moisturizing effect |
| Example 1 | 25 | 36 | 24 |
| Example 2 | 27 | 37 | 26 |
| Example 3 | 28 | 37 | 28 |
| Comparative example 1 | 19 | 30 | 20 |
| Comparative example 2 | 21 | 15 | 22 |
As can be seen from table 4, the volunteers have high acceptance of the wrinkle-removing essence creams of examples 1 to 3, which all indicate that the wrinkle-removing essence cream of the present invention is easy to absorb, has a good moisturizing effect and an obvious wrinkle-removing effect, and after one month of trial, the fine wrinkles on the face are obviously smoothed or reduced. The wrinkle-removing effect and the moisturizing effect of the product using the comparative example are not as good as the control effect of the wrinkle-removing essence cream of the invention,
the above description is only for the specific embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention, and all the changes or substitutions should be covered within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the appended claims.
Claims (10)
1. The wrinkle-removing essence cream is characterized by being prepared from a phase A, a phase B and a phase C, wherein the phase A, the phase B and the phase C comprise the following raw materials:
phase A: water; urea; butanediol; sorbitol; sodium hyaluronate; carbomer;
phase B: a polydimethylsiloxane cross-linked polymer; caprylic/capric triglyceride; hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymers;
and C phase: a mixture of soluble collagen, hexylene glycol, glycerol and water; a mixture of glycerol, water, butylene glycol, carbomer, polysorbate-20, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-7; a mixture of butylene glycol, 1, 2-hexanediol, capryloyl glycine, and capryloyl hydroxamic acid; acetyl hexapeptide-8; carnosine; arginine; and (4) essence.
2. The wrinkle-removing essence cream according to claim 1, wherein the wrinkle-removing essence cream is prepared from a phase A, a phase B and a phase C, and the phase A, the phase B and the phase C comprise the following raw materials in parts by weight:
phase A: 60-68 parts of water; 4-8 parts of urea; 4-6 parts of butanediol; 4-6 parts of sorbitol; 0.05-0.15 part of sodium hyaluronate; 0.03-0.07 part of carbomer;
phase B: 6-10 parts of polydimethylsiloxane cross-linked polymer; 2-4 parts of caprylic/capric triglyceride; 1-3 parts of hydroxyethyl acrylate/acryloyl dimethyl sodium taurate copolymer;
and C phase: 4-6 parts of a mixture of soluble collagen, hexanediol, glycerol and water; 1-3 parts of a mixture of glycerol, water, butanediol, carbomer, polysorbate-20, palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7; 0.5-0.9 part of mixture of butanediol, 1, 2-hexanediol, caprylyl glycine and caprylyl hydroximic acid; acetyl hexapeptide-80.00008-0.00012 portion; 0.05-0.15 part of carnosine; 0.02-0.04 part of arginine; 0.01-0.03 part of essence.
3. The wrinkle-removing essence cream according to claim 2, wherein the wrinkle-removing essence cream is prepared from phase A, phase B, phase C and phase D, and the phase A, the phase B, the phase C and the phase D comprise the following raw materials in parts by weight:
phase A: 63 parts of water; 6 parts of urea; 5 parts of butanediol; 5 parts of sorbitol; 0.1 part of sodium hyaluronate; 0.05 part of carbomer;
phase B: 8 parts of polydimethylsiloxane cross-linked polymer; 3 parts of caprylic/capric triglyceride; 2 parts of hydroxyethyl acrylate/acryloyl dimethyl sodium taurate copolymer;
and C phase: 5 parts of a mixture of soluble collagen, hexanediol, glycerol and water; 2 parts of a mixture of glycerol, water, butanediol, carbomer, polysorbate-20, palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7; 0.7 part of a mixture of butanediol, 1, 2-hexanediol, caprylyl glycine and caprylyl hydroximic acid; 80.0001 parts of acetyl hexapeptide; 0.1 part of carnosine; 0.03 part of arginine; 0.02 part of essence.
4. The wrinkle-removing essence cream according to claim 2 or 3, wherein glycerin is added in an amount of 53.5% by weight of the mixture, water is added in an amount of 25% by weight of the mixture, butylene glycol is added in an amount of 20% by weight of the mixture, carbomer is added in an amount of 1% by weight of the mixture, polysorbate-20 is added in an amount of 0.5% by weight of the mixture, palmitoyl tripeptide-1 is added in the mixture in an amount of 100PPm, and palmitoyl tetrapeptide-7 is added in the mixture in an amount of 50 PPm.
5. The wrinkle-removing essence cream according to claim 2 or 3, wherein the ratio of the addition amount of butanediol, 1, 2-hexanediol, caprylylglycine and caprylhydroxamic acid in the mixture of butanediol, 1, 2-hexanediol, caprylylglycine and caprylhydroxamic acid is 31: 58: 5: 6.
6. the wrinkle-removing essence cream according to claim 2 or 3, wherein the ratio of the addition amount of the soluble collagen, the hexanediol, the glycerin and the water in the mixture of the soluble collagen, the hexanediol, the glycerin and the water is 0.4: 2: 30: 67.6.
7. the method for preparing the wrinkle-removing essence cream according to any one of claims 1 to 6, wherein the method comprises the steps of:
(1) mixing and homogenizing all the raw materials in the phase A, stirring and heating until all the raw materials in the phase A are completely dissolved until no particles exist, uniformly mixing to form a phase A mixture, and keeping the temperature for later use;
(2) mixing all the raw materials in the phase B, stirring until the raw materials are uniformly mixed to form a phase B mixture, adding the phase B mixture into the phase A mixture obtained in the step (1), stirring and mixing, homogenizing again, and then preserving heat for 15-25 minutes to form a mixture of the phase A and the phase B;
(3) cooling to below 40 deg.C, adding all the raw materials of phase C, and stirring; degassing and filtering to obtain the wrinkle-removing essence cream.
8. The preparation method of the wrinkle-removing essence cream according to claim 4, wherein in the step (1), all the raw materials in the phase A are mixed and homogenized, stirred and heated to 83-87 ℃ until all the raw materials in the phase A are completely dissolved to be free of particles.
9. The method for preparing the wrinkle-removing essence cream according to claim 4, wherein in the step (1), the pre-used utensils are washed with sterilized water of 80 ℃ or higher, then washed with 75% sterilized alcohol, and then all the raw materials in the phase A are mixed and homogenized in the main kettle.
10. The method for preparing the wrinkle-removing essence cream according to claim 4, wherein in the step (2), the re-homogenization time is 5 minutes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010256561.3A CN111329784A (en) | 2020-04-02 | 2020-04-02 | Wrinkle-removing essence cream and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010256561.3A CN111329784A (en) | 2020-04-02 | 2020-04-02 | Wrinkle-removing essence cream and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN111329784A true CN111329784A (en) | 2020-06-26 |
Family
ID=71176854
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010256561.3A Pending CN111329784A (en) | 2020-04-02 | 2020-04-02 | Wrinkle-removing essence cream and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN111329784A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112618404A (en) * | 2020-12-02 | 2021-04-09 | 天津芸熙生物技术有限公司 | Application of sandalwood polypeptide in preparation of skin care product and composition thereof |
| CN114224772A (en) * | 2021-12-15 | 2022-03-25 | 江苏江山聚源生物技术有限公司 | Anti-wrinkle composition and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2755767A1 (en) * | 2010-10-19 | 2012-04-19 | Eric F. Bernstein | A skin composition comprising an exfoliate, a brightener and a collagen booster, and method of using the same |
| CN109464337A (en) * | 2018-12-23 | 2019-03-15 | 广州航美化妆品有限公司 | Compact anti-wrinkle essence |
-
2020
- 2020-04-02 CN CN202010256561.3A patent/CN111329784A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2755767A1 (en) * | 2010-10-19 | 2012-04-19 | Eric F. Bernstein | A skin composition comprising an exfoliate, a brightener and a collagen booster, and method of using the same |
| CN109464337A (en) * | 2018-12-23 | 2019-03-15 | 广州航美化妆品有限公司 | Compact anti-wrinkle essence |
Non-Patent Citations (2)
| Title |
|---|
| 叨叨丸子: "详扒Buffet/一个The Ordinary 家的引路人", 《简书 HTTPS://WWW.JIANSHU.COM/P/240BC975B882》 * |
| 裘炳毅, 中国轻工业出版社 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112618404A (en) * | 2020-12-02 | 2021-04-09 | 天津芸熙生物技术有限公司 | Application of sandalwood polypeptide in preparation of skin care product and composition thereof |
| CN114224772A (en) * | 2021-12-15 | 2022-03-25 | 江苏江山聚源生物技术有限公司 | Anti-wrinkle composition and preparation method thereof |
| CN114224772B (en) * | 2021-12-15 | 2024-03-15 | 江苏江山聚源生物技术有限公司 | Anti-wrinkle composition and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN108113914B (en) | Essence cream without essence and preservative and preparation method thereof | |
| CN110115691B (en) | Whitening and skin-tendering emulsion containing rice fermentation product and preparation method thereof | |
| CN111643411B (en) | Anti-aging composition and application thereof | |
| CN111329784A (en) | Wrinkle-removing essence cream and preparation method thereof | |
| CN114848541A (en) | Anti-aging and wrinkle-removing composition and preparation method thereof, and cosmetic and preparation method thereof | |
| CN110755328A (en) | Beautifying, moisturizing and repairing composition and application thereof | |
| CN106902030A (en) | Skin care compositions and cosmetics with moisturizing, smoothing wrinkle and the elastic effect of recovery | |
| CN116549372A (en) | Antioxidant composition enhanced by heat as well as preparation method and application thereof | |
| CN111358704A (en) | Deep-repairing anti-aging composition and preparation method and application thereof | |
| CN107929220A (en) | It is a kind of that there is stem cell skin care compound for repairing anti-aging function and preparation method thereof | |
| CN111434332A (en) | Nourishing and repairing emulsion and preparation method thereof | |
| CN107224418B (en) | Natural sleep-aiding beauty mask and preparation method thereof | |
| CN113384482A (en) | Moisturizing and skin-tendering essence and preparation method thereof | |
| CN113101256A (en) | Anti-aging repair nanoemulsion and application thereof | |
| CN108309851A (en) | A kind of face cream with anti-senescence function | |
| CN112137942A (en) | Anti-aging traditional Chinese medicine composition and application thereof | |
| CN111870574A (en) | Lucid ganoderma compound skin care product and preparation method thereof | |
| CN106667856A (en) | Calming anti-allergy skin care composition and skin care product | |
| CN111012699A (en) | Antioxidant oil-controlling emulsion containing fucoidan-kelp extract | |
| CN114028291B (en) | Composition for improving dark eye circles and preparation method and application thereof | |
| CN111053721B (en) | Silky glowing eye cream and preparation method thereof | |
| CN110025515B (en) | Anti-allergy polysaccharide compound composition and application thereof in cosmetics | |
| CN114159333A (en) | Muscle foundation liquid and preparation method thereof | |
| CN112972314A (en) | Eye repair composition and preparation method and application thereof | |
| CN108324613A (en) | A kind of face cream and preparation method thereof of desalination wrinkle |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20200626 |