CN111317807A - Traditional Chinese medicine composition for treating chronic pharyngolaryngitis, preparation and preparation method of preparation - Google Patents

Traditional Chinese medicine composition for treating chronic pharyngolaryngitis, preparation and preparation method of preparation Download PDF

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CN111317807A
CN111317807A CN201911396568.9A CN201911396568A CN111317807A CN 111317807 A CN111317807 A CN 111317807A CN 201911396568 A CN201911396568 A CN 201911396568A CN 111317807 A CN111317807 A CN 111317807A
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traditional chinese
chinese medicine
preparation
treating chronic
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叶松宽
周冬焦
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Hangzhou Kuansong Biotechnology Co ltd
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Hangzhou Kuansong Biotechnology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
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    • A61K36/30Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/34Campanulaceae (Bellflower family)
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/752Citrus, e.g. lime, orange or lemon
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8888Pinellia
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968Ophiopogon (Lilyturf)
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/906Zingiberaceae (Ginger family)
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    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P11/04Drugs for disorders of the respiratory system for throat disorders

Abstract

The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating chronic pharyngolaryngitis, a preparation and a preparation method of the preparation. The composition comprises the following components in parts by weight: 8-15 parts of burdock, 8-16 parts of blackberry lily, 4-10 parts of bamboo shavings, 3-9 parts of exocarpium citri grandis, 8-14 parts of rhizoma pinellinae praeparata, 6-12 parts of radix rehmanniae, 4-10 parts of radix ophiopogonis, 8-14 parts of salvia miltiorrhiza, 4-10 parts of codonopsis pilosula, 10-16 parts of houttuynia cordata, 1-7 parts of dried ginger, 5-11 parts of lithospermum, 5-12 parts of fructus aurantii, 3-9 parts of peach kernel, 3-10 parts of safflower carthamus, 8-14 parts of radix bupleuri, 3-9 parts of radix clematidis, 3-10 parts of fructus evodiae, 1-7 parts of rhizoma cimicifugae and 8-14 parts. The invention discloses a traditional Chinese medicine preparation for treating chronic pharyngolaryngitis and a preparation method thereof, wherein the traditional Chinese medicine preparation is prepared according to a scientific proportion, has the functions of diminishing inflammation, relieving cough, reducing phlegm and the like, and is safe, reliable and free of toxic and side effects.

Description

Traditional Chinese medicine composition for treating chronic pharyngolaryngitis, preparation and preparation method of preparation
Technical Field
The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating chronic pharyngolaryngitis, a preparation and a preparation method of the preparation.
Background
Pharyngolaryngitis is a common and frequently encountered disease in clinic, has a score of acute and chronic diseases, and belongs to a part of upper respiratory tract infection. When acute pharyngolaryngitis occurs, patients often feel sore throat, accompanied by symptoms of hurriess, uncomfortable pharynx, lack of pronunciation, dry throat, much thought of drinking, or foreign body sensation in throat, and the like, and when severe, symptoms of fever, cold intolerance, headache, aching pain in the whole body, poor appetite, dry stool, thirst and the like can also occur, and if the treatment is not timely or repeatedly performed, the chronic pharyngolaryngitis is converted into the chronic pharyngolaryngitis.
The diseases are caused by a plurality of reasons, mainly caused by heat toxin stagnation and floating up to the throat due to the dysfunction of viscera, and patients often feel uncomfortable, dry, itchy and swollen, have a lot of secretions and burning pain, are easy to dry and feel bad, have foreign body sensation, cannot be swallowed, and the symptoms are aggravated when speaking a little bit more, eating irritant food, fatigue or weather change. According to the theory of traditional Chinese medicine, the pharynx is the stomach, the larynx is the lung, the larynx is easily injured by exogenous pathogenic factors entering the lung, the pharynx is easily injured by improper diet entering the stomach, and the larynx is a place where the pathogenic toxin is well soaked for a long time. At present, the medicines for treating the sphagitis are various, western medicines mainly comprise antibiotics, the medicines have common curative effect and quick response, but cannot be taken for a long time, and some medicines have certain side effect on a body and cannot radically treat the chronic sphagitis. At present, many traditional Chinese medicines for treating sphagitis are available, but some traditional Chinese medicines have slow effect and poor curative effect.
Therefore, the seeking of a traditional Chinese medicine preparation for treating the sphagitis, which can exert the characteristics of the traditional Chinese medicine and is popular, is an objective requirement which can be matched with the popular psychology of sphagitis patients.
Disclosure of Invention
In order to solve the technical effects, the invention provides a traditional Chinese medicine composition for treating chronic pharyngolaryngitis;
the invention is realized by the following steps:
a traditional Chinese medicine composition for treating chronic pharyngolaryngitis comprises the following components in parts by weight: 8-15 parts of burdock, 8-16 parts of blackberry lily, 4-10 parts of bamboo shavings, 3-9 parts of exocarpium citri grandis, 8-14 parts of rhizoma pinellinae praeparata, 6-12 parts of radix rehmanniae, 4-10 parts of radix ophiopogonis, 8-14 parts of salvia miltiorrhiza, 4-10 parts of codonopsis pilosula, 10-16 parts of houttuynia cordata, 1-7 parts of dried ginger, 5-11 parts of lithospermum, 5-12 parts of fructus aurantii immaturus shell, 3-9 parts of peach kernel, 3-10 parts of safflower carthamus, 8-14 parts of radix bupleuri, 3-9 parts of radix clematidis, 3-10 parts of fructus evodiae, 1-7 parts of rhizoma cimicifugae and 8-.
Further, the traditional Chinese medicine composition for treating chronic pharyngolaryngitis comprises the following components in parts by weight: 10-13 parts of burdock, 10-14 parts of blackberry lily, 6-8 parts of bamboo shavings, 5-7 parts of pummelo peel, 10-12 parts of rhizoma pinellinae praeparata, 8-10 parts of radix rehmanniae, 6-8 parts of radix ophiopogonis, 10-12 parts of salvia miltiorrhiza, 6-8 parts of codonopsis pilosula, 12-14 parts of houttuynia cordata, 3-5 parts of dried ginger, 7-9 parts of lithospermum, 7-10 parts of fructus aurantii, 5-7 parts of peach kernel, 5-8 parts of safflower, 10-12 parts of radix bupleuri, 5-7 parts of radix clematidis, 5-8 parts of fructus evodiae, 3-5 parts of rhizoma cimicifugae and 10-12 parts of myrobalan meat.
Further, the traditional Chinese medicine composition for treating chronic pharyngolaryngitis comprises the following components in parts by weight: 12 parts of burdock, 12 parts of blackberry lily, 7 parts of bamboo shavings, 6 parts of pummelo peel, 11 parts of rhizoma pinellinae praeparata, 9 parts of radix rehmanniae, 7 parts of thunberg dwarf lilyturf tuber, 12 parts of salvia miltiorrhiza, 7 parts of codonopsis pilosula, 13 parts of houttuynia cordata, 4 parts of dried ginger, 8 parts of lithospermum, 9 parts of fructus aurantii, 6 parts of peach kernel, 7 parts of safflower, 11 parts of radix bupleuri, 6 parts of radix clematidis, 7 parts of fructus evodiae, 4 parts of rhizoma cimicifugae and 11 parts.
The invention also provides a traditional Chinese medicine preparation for treating chronic pharyngolaryngitis, which specifically comprises the following technical scheme:
the Chinese medicinal preparation can be made into powder, tablet, granule, oral liquid, pill or capsule.
The preparation method of the traditional Chinese medicine preparation comprises the steps of drying each component of the traditional Chinese medicine composition, crushing the components into medicinal powder and mixing the medicinal powder to obtain the optimal traditional Chinese medicine powder, and carrying out ultrasonic extraction on the extract liquid after the extract liquid is mixed with each component by an extracting agent to obtain the powder.
Further, the pulverization method includes a grinding and mixing method.
Furthermore, various traditional Chinese medicine components are dried and then crushed into 80-150 meshes of medicinal powder.
Preferably, the preparation method of the traditional Chinese medicine preparation comprises the steps of uniformly mixing the components of the traditional Chinese medicine composition with auxiliary materials to obtain a mixture, adding a wetting agent of pure water into the mixture to uniformly wet the mixture to prepare a soft material, and extruding the soft material to obtain the traditional Chinese medicine granules.
Furthermore, the auxiliary materials comprise any one or a composition of more than two of a disintegrating agent, a flow aid, a suspending agent and a wetting agent, and also comprise mannitol and microcrystalline cellulose.
Further, mannitol: the weight percentage of the microcrystalline cellulose is 6.45-16: 1.
the beneficial effect of above-mentioned scheme:
the invention discloses a Chinese medicinal preparation for treating chronic pharyngolaryngitis and a preparation method thereof, wherein the Chinese medicinal preparation is prepared according to a scientific proportion, has the functions of diminishing inflammation, relieving cough, reducing phlegm and the like, and is safe, reliable and free from toxic and side effects.
Detailed Description
The technical solutions of the present invention are described clearly and completely below, and it is obvious that the described embodiments are some, not all embodiments of the present invention. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, are within the scope of the present invention.
Introduction of raw materials:
and (3) burdock: has antitumor, antiinflammatory, antidiabetic, antibacterial and antiviral effects.
Shooting: it is indicated for cough and dyspnea due to excessive phlegm and saliva. Swollen and sore throat, obstruction of urination and defecation, failure of various medicines, abdominal dropsy, blackened skin and initial acute mastitis.
Bamboo shavings: can be used for treating phlegm-heat cough, gallbladder fire with phlegm, palpitation, vexation, insomnia, apoplexy, phlegm stagnation, stiff tongue, stomach heat emesis, vomiting, pregnancy obstruction, and threatened abortion.
Pummelo peel: resolving phlegm, regulating qi, invigorating spleen and promoting digestion, and can be used for relieving phlegm stagnation in chest, cough and asthma.
Rhizoma pinelliae preparata: dry dampness and resolve phlegm. Can be used for treating cough and asthma due to excessive phlegm, dizziness and palpitation due to phlegm and fluid retention, dizziness due to wind-phlegm, and headache due to phlegm syncope.
Radix rehmanniae: can be used for treating yin impairment due to febrile disease, crimson tongue with dipsosis, toxic heat, macula, hematemesis, epistaxis, and sore throat. Sheng Di Huang clears heat and cools blood, and nourishes yin and promotes the production of body fluid. Can be used for treating heat entering nutrient-blood, epidemic febrile disease, macula, hematemesis, epistaxis, yin injury due to fever, crimson tongue, polydipsia, constipation due to body fluid consumption, fever due to yin deficiency, bone steaming, overstrain and internal heat, and diabetes.
Zhe ophiopogon root: has effects in nourishing yin, promoting salivation, moistening lung, relieving cough, clearing away heart-fire, and relieving restlessness. Can be used for treating dry cough due to lung dryness, little body fluid, thirst, vexation, constipation, etc.
Red sage root: promoting blood circulation, dispelling blood stasis, dredging meridians, relieving pain, clearing away heart-fire, relieving restlessness, cooling blood, and eliminating carbuncle. Can be used for treating thoracic obstruction, heart pain, abdominal pain, hypochondriac pain, abdominal mass, pain due to pyretic arthralgia, vexation, insomnia, menoxenia, dysmenorrhea, amenorrhea, and pyocutaneous disease with swelling and pain.
Codonopsis pilosula: tonify middle-jiao and Qi, harmonize stomach and promote fluid production, dispel phlegm and relieve cough. Can be used for treating spleen deficiency, anorexia, loose stool, weakness of limbs, palpitation, short breath, xerostomia, spontaneous perspiration, proctoptosis, and abnormal yin.
Houttuynia cordata: clear heat and remove toxicity, induce diuresis and alleviate edema. Treating pneumonia, lung abscess, dysentery, malaria, edema, gonorrhea, leucorrhea, carbuncle, swelling, hemorrhoid, rectocele, eczema, alopecia, scabies and tinea.
Dried ginger: warming the middle energizer to dispel cold, restoring yang to activate collaterals, warming the lung to resolve retained fluid.
Lithospermum: sweet, salty and cold. Cool blood, activate blood, remove toxicity and promote eruption.
Fructus aurantii: can be used for treating qi stagnation in chest and hypochondrium, fullness and pain, dyspepsia, phlegm retention, gastroptosis, proctoptosis, and uterine prolapse.
Peach kernel: promote blood circulation to remove blood stasis, moisten intestines to relieve constipation, relieve cough and relieve asthma.
Safflower: promoting blood circulation, dredging channels, removing blood stasis and relieving pain. It is indicated for amenorrhea, abdominal mass, dystocia, dead fetus, postpartum lochiorrhea, pain due to blood stasis, carbuncle, swelling and traumatic injury.
Bupleurum root: harmonize exterior and interior, soothe liver, relieve depression, raise yang, lift sinking, allay fever and check malaria.
Clematis root: can be used for treating rheumatalgia, numbness of limbs, spasm of tendons and vessels, and difficulty in flexion and extension.
Evodia fruit: can be used for treating syncope headache, hernia of cold, abdominal pain, tinea pedis due to cold dampness, abdominal pain during menstruation, abdominal pain, emesis, acid regurgitation, and diarrhea before dawn.
Cimicifugae foetidae: mainly treats seasonal pestilence, headache, cold and heat, laryngalgia, aphtha and impenetrable macula; sinking of middle qi, chronic diarrhea, dysentery, rectocele, metrorrhagia, leukorrhagia, and metrostaxis; abscess, swelling and sore.
Myrobalan meat: it is indicated for astringing intestine to astringe lung, purging fire and relieving sore throat. Can be used for treating chronic diarrhea, dysentery, proctoptosis due to hematochezia, cough and asthma due to lung deficiency, chronic cough, pharyngalgia, and hoarseness.
In the embodiment, the burdock and the blackberry lily are monarch drugs, the bamboo shavings, the pummelo peel, the cimicifuga foetida, the rhizoma pinellinae praeparata, the houttuynia cordata, the lithospermum and the fructus aurantii are ministerial drugs with the main effects of clearing stomach heat and lung heat, and the radix rehmanniae, the radix ophiopogonis, the salvia miltiorrhiza, the codonopsis pilosula and the myrobalan pulp are adjuvant drugs.
The embodiment provides a traditional Chinese medicine composition for treating chronic pharyngolaryngitis, which comprises the following components in parts by weight:
8-15 parts of burdock, 8-16 parts of blackberry lily, 4-10 parts of bamboo shavings, 3-9 parts of exocarpium citri grandis, 8-14 parts of rhizoma pinellinae praeparata, 6-12 parts of radix rehmanniae, 4-10 parts of radix ophiopogonis, 8-14 parts of salvia miltiorrhiza, 4-10 parts of codonopsis pilosula, 10-16 parts of houttuynia cordata, 1-7 parts of dried ginger, 5-11 parts of lithospermum, 5-12 parts of fructus aurantii, 3-9 parts of peach kernel, 3-10 parts of safflower carthamus, 8-14 parts of radix bupleuri, 3-9 parts of radix clematidis, 3-10 parts of fructus evodiae, 1-7 parts of rhizoma cimicifugae and 8-14 parts.
Example 1
The embodiment provides a traditional Chinese medicine composition for treating chronic pharyngolaryngitis, which comprises the following components in parts by weight:
10 parts of burdock, 10 parts of blackberry lily, 6 parts of bamboo shavings, 5 parts of pummelo peel, 10 parts of rhizoma pinellinae praeparata, 8 parts of radix rehmanniae, 6 parts of Zhejiang radix ophiopogonis, 10 parts of salvia miltiorrhiza, 6 parts of codonopsis pilosula, 12 parts of houttuynia cordata, 3 parts of dried ginger, 7 parts of lithospermum, 7 parts of fructus aurantii, 5 parts of peach kernel, 5 parts of safflower, 10 parts of radix bupleuri, 5 parts of radix clematidis, 5 parts of fructus evodiae, 3 parts of rhizoma cimicifugae and 10 parts of myrobalan.
The embodiment also provides a traditional Chinese medicine preparation for treating chronic pharyngolaryngitis, which comprises powder consisting of the components and a preparation method of the traditional Chinese medicine preparation, wherein the specific preparation method comprises the following steps:
(1) crushing: drying the Chinese medicinal materials respectively, and pulverizing into medicinal powder;
(2) mixing: mixing the medicinal powders by grinding;
(3) packaging: packaging the mixed medicinal powder according to a certain weight.
In this embodiment, in step (1), the various Chinese medicinal components are dried and then pulverized into 80-150 mesh powder.
In this embodiment, in step (3), the powdered medicine is packaged by cellophane, wax paper and aluminum plastic bag.
In this example, in step (3), the powder is packaged in a weight of 1-2 g.
The traditional Chinese medicine is pulverized by a traditional Chinese medicine pulverizer, and for traditional Chinese medicine components with high humidity or high viscosity, the traditional Chinese medicine components can be put into a pot, heated by soft fire and turned over to uniformly heat the traditional Chinese medicine until the medicine is dried, and then pulverized.
In this example, mixing is a process of cross-dispersing a plurality of solid powders with each other. By the operation, all the medicines in the powder can be uniformly mixed and have consistent color. The usual mixing methods are generally grinding mixing, stirring mixing and sieving mixing.
The packaging process is to divide the uniformly mixed powder into equal parts by weight according to the required dosage and package the powder by adopting a packaging material. The powder has large specific surface area, is easy to absorb moisture, block, discolor and decompose, so that the curative effect and the taking are influenced, and therefore, the moisture absorption of the powder needs to be delayed by selecting proper packaging materials and storage conditions. The common packaging materials include glossy paper, cellophane, wax paper, glass bottles, plastic bottles, hard capsules, aluminum plastic bags, polyethylene plastic film bags and the like. The powder should be stored in a cool and dry environment, and stored in different categories and checked regularly.
Example 2
The embodiment provides a traditional Chinese medicine composition for treating chronic pharyngolaryngitis, which comprises the following components in parts by weight:
13 parts of burdock, 14 parts of blackberry lily, 8 parts of bamboo shavings, 7 parts of pummelo peel, 12 parts of rhizoma pinellinae praeparata, 10 parts of radix rehmanniae, 8 parts of Zhejiang radix ophiopogonis, 12 parts of salvia miltiorrhiza, 8 parts of codonopsis pilosula, 14 parts of houttuynia cordata, 5 parts of dried ginger, 9 parts of lithospermum, 10 parts of fructus aurantii, 7 parts of peach kernel, 8 parts of safflower, 12 parts of radix bupleuri, 7 parts of radix clematidis, 8 parts of fructus evodiae, 5 parts of rhizoma cimicifugae and 12 parts of myrobalan.
The embodiment also provides a traditional Chinese medicine preparation for treating chronic pharyngolaryngitis, which comprises granules consisting of the components and a preparation method of the traditional Chinese medicine preparation, wherein the specific preparation method comprises the following steps:
the components are uniformly mixed according to the weight portion of the embodiment 2, then the wetting agent pure water is added for uniform wetting to prepare a soft material, the soft material is extruded and granulated by an extruder at the speed of 10-45r/min, the particles are rolled for 5-30min at high speed and centrifugal, the rotating speed is 200-1000r/min, the blowing frequency is 10-30Hz, a proper amount of pure water is intermittently sprayed by a spray gun, the rotating speed of a peristaltic pump is 4-9r/min, the atomizing pressure is 0.3-0.7Mpa until the particles are rolled into balls, the balls are collected, the drying is carried out at the temperature of 35-80 ℃, and the filling amount is determined and.
Example 3
The embodiment provides a traditional Chinese medicine composition for treating chronic pharyngolaryngitis, which comprises the following components in parts by weight:
12 parts of burdock, 12 parts of blackberry lily, 7 parts of bamboo shavings, 6 parts of pummelo peel, 11 parts of rhizoma pinellinae praeparata, 9 parts of radix rehmanniae, 7 parts of thunberg dwarf lilyturf tuber, 12 parts of salvia miltiorrhiza, 7 parts of codonopsis pilosula, 13 parts of houttuynia cordata, 4 parts of dried ginger, 8 parts of lithospermum, 9 parts of fructus aurantii, 6 parts of peach kernel, 7 parts of safflower, 11 parts of radix bupleuri, 6 parts of radix clematidis, 7 parts of fructus evodiae, 4 parts of rhizoma cimicifugae and 11 parts.
The embodiment also provides a traditional Chinese medicine preparation for treating chronic pharyngolaryngitis, which comprises a decoction prepared from the components and a preparation method of the decoction, wherein the specific preparation method comprises the following steps:
taking the above composition, adding 500ml water, soaking for 30 minutes, heating and decocting for 30 minutes, filtering, transferring the collected filtrate to a 500ml volumetric flask, fixing the volume to the scale with water, and filtering with a 0.45 μm microporous membrane to obtain the traditional Chinese medicine decoction.
Experimental example 1
Clinical trial effect
(1) Clinical data
400 patients with pharyngolaryngitis, 200 men and 200 women are averagely divided into 4 groups, and each group comprises 100 patients, wherein the maximum age is 72 years old, the minimum age is 6 years old, the longest course of disease is 10 years, and the shortest course of disease is 10 days.
(2) Basis of treatment
The mild patient has symptoms of throat red swelling, pain, chapping, erosion, dysphagia, etc.; severe cases are accompanied by symptoms such as headache, fever, cough, etc.
(3) Method of treatment
The product prepared by the method of the invention in the embodiment 1-3 and other products are respectively taken by 4 groups of patients for 2 times per day, 200 ml each time, and 400 ml per day. Two weeks is a course of treatment.
(4) Matters of attention
Tea drinking and sour food are prohibited.
(5) Assessment of efficacy
And (3) healing: the symptoms such as red swelling, erosion, cough and pain, dysphagia and the like completely disappear;
improvement: the symptoms such as red swelling, erosion, cough and pain, dysphagia and the like are obviously relieved;
and (4) invalidation: the clinical symptoms are not improved.
(6) Analysis of efficacy
The effective rate of the traditional Chinese medicine preparation for treating sphagitis is over 91 percent.
The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (10)

1. A traditional Chinese medicine composition for treating chronic pharyngolaryngitis is characterized by comprising the following components in parts by weight: 8-15 parts of burdock, 8-16 parts of blackberry lily, 4-10 parts of bamboo shavings, 3-9 parts of exocarpium citri grandis, 8-14 parts of rhizoma pinellinae praeparata, 6-12 parts of radix rehmanniae, 4-10 parts of radix ophiopogonis, 8-14 parts of salvia miltiorrhiza, 4-10 parts of codonopsis pilosula, 10-16 parts of houttuynia cordata, 1-7 parts of dried ginger, 5-11 parts of lithospermum, 5-12 parts of fructus aurantii, 3-9 parts of peach kernel, 3-10 parts of safflower carthamus, 8-14 parts of radix bupleuri, 3-9 parts of radix clematidis, 3-10 parts of fructus evodiae, 1-7 parts of rhizoma cimicifugae and 8-14 parts.
2. The traditional Chinese medicine composition for treating chronic pharyngolaryngitis according to claim 1, which is characterized by comprising the following components in parts by weight: 10-13 parts of burdock, 10-14 parts of blackberry lily, 6-8 parts of bamboo shavings, 5-7 parts of pummelo peel, 10-12 parts of rhizoma pinellinae praeparata, 8-10 parts of radix rehmanniae, 6-8 parts of radix ophiopogonis, 10-12 parts of salvia miltiorrhiza, 6-8 parts of codonopsis pilosula, 12-14 parts of houttuynia cordata, 3-5 parts of dried ginger, 7-9 parts of lithospermum, 7-10 parts of fructus aurantii, 5-7 parts of peach kernel, 5-8 parts of safflower, 10-12 parts of radix bupleuri, 5-7 parts of radix clematidis, 5-8 parts of fructus evodiae, 3-5 parts of rhizoma cimicifugae and 10-12 parts of myrobalan meat.
3. The traditional Chinese medicine composition for treating chronic pharyngolaryngitis according to claim 1, which is characterized by comprising the following components in parts by weight: 12 parts of burdock, 12 parts of blackberry lily, 7 parts of bamboo shavings, 6 parts of pummelo peel, 11 parts of rhizoma pinellinae praeparata, 9 parts of radix rehmanniae, 7 parts of thunberg dwarf lilyturf tuber, 112 parts of salvia miltiorrhiza, 7 parts of codonopsis pilosula, 13 parts of houttuynia cordata, 4 parts of dried ginger, 8 parts of lithospermum, 9 parts of fructus aurantii, 6 parts of peach kernel, 7 parts of safflower, 11 parts of radix bupleuri, 6 parts of radix clematidis, 7 parts of fructus evodiae, 4 parts of rhizoma cimicifugae and 11 parts.
4. A traditional Chinese medicine preparation for treating chronic pharyngolaryngitis is characterized in that the dosage form of the traditional Chinese medicine preparation is any one of powder, tablets, granules, oral liquid, pills and capsules.
5. The traditional Chinese medicine preparation for treating chronic pharyngolaryngitis according to claim 4, wherein the preparation method of the traditional Chinese medicine preparation comprises the steps of drying the components of the traditional Chinese medicine composition according to any one of claims 1 to 3, crushing the components into medicinal powder, and mixing the medicinal powder to obtain traditional Chinese medicine powder.
6. The traditional Chinese medicine preparation for treating chronic pharyngolaryngitis according to claim 5, wherein the crushing method comprises a grinding and mixing method.
7. The traditional Chinese medicine preparation for treating chronic pharyngolaryngitis according to claim 6, wherein the various traditional Chinese medicine components are dried and then crushed into 80-150 meshes of medicinal powder.
8. The preparation method of the traditional Chinese medicine preparation for treating chronic pharyngolaryngitis according to claim 4, wherein the preparation method of the traditional Chinese medicine preparation comprises the steps of uniformly mixing the components of the traditional Chinese medicine composition according to any one of claims 1 to 3 and auxiliary materials to obtain a mixture, adding a wetting agent and pure water to the mixture, uniformly wetting the mixture to prepare a soft material, and extruding the soft material to obtain the traditional Chinese medicine granule.
9. The traditional Chinese medicine preparation for treating chronic pharyngolaryngitis according to claim 8, wherein the auxiliary materials comprise one or a combination of more than two of disintegrating agent, glidant, suspending agent and wetting agent, and also comprise mannitol and microcrystalline cellulose.
10. The traditional Chinese medicine preparation for treating chronic pharyngolaryngitis according to claim 9, wherein the ratio of mannitol: the weight percentage of the microcrystalline cellulose is 6.45-16: 1.
CN201911396568.9A 2019-12-30 2019-12-30 Traditional Chinese medicine composition for treating chronic pharyngolaryngitis, preparation and preparation method of preparation Pending CN111317807A (en)

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