CN111295454A - 靶向染色体不稳定性和下游胞质dna信号传导以治疗癌症 - Google Patents

靶向染色体不稳定性和下游胞质dna信号传导以治疗癌症 Download PDF

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CN111295454A
CN111295454A CN201880058523.8A CN201880058523A CN111295454A CN 111295454 A CN111295454 A CN 111295454A CN 201880058523 A CN201880058523 A CN 201880058523A CN 111295454 A CN111295454 A CN 111295454A
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cells
cell
cgamp
sample
cancer
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L·C·坎特利
B·恩格
S·F·巴库姆
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Cornell University
Memorial Sloan Kettering Cancer Center
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Cornell University
Memorial Sloan Kettering Cancer Center
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CN201880058523.8A 2017-07-10 2018-07-10 靶向染色体不稳定性和下游胞质dna信号传导以治疗癌症 Pending CN111295454A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762530661P 2017-07-10 2017-07-10
US62/530,661 2017-07-10
PCT/US2018/041480 WO2019014246A1 (en) 2017-07-10 2018-07-10 TARGETING CHROMOSOMIC INSTABILITY AND SIGNALING OF CYTOSOLIC DNA IN AVAL FOR THE TREATMENT OF CANCER

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CN111295454A true CN111295454A (zh) 2020-06-16

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US (2) US11821042B2 (https=)
EP (1) EP3652349A1 (https=)
JP (1) JP7197556B2 (https=)
KR (1) KR20200037796A (https=)
CN (1) CN111295454A (https=)
AU (1) AU2018300007A1 (https=)
BR (1) BR112020000477A2 (https=)
CA (1) CA3069515A1 (https=)
IL (1) IL271849A (https=)
MX (1) MX2020000406A (https=)
SG (1) SG11202000132WA (https=)
WO (1) WO2019014246A1 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109789180A (zh) * 2016-09-02 2019-05-21 伊利诺伊大学理事会 Kif13b衍生的肽和抑制血管生成的方法
CN113341154A (zh) * 2021-05-14 2021-09-03 医工瑞思(福建)工程研究中心有限公司 一种检测血栓或凝血相关疾病的生物标志物及其应用
CN115354078A (zh) * 2022-09-02 2022-11-18 中山大学附属第一医院 骨肉瘤检测标记物及其应用

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2018300007A1 (en) 2017-07-10 2020-02-27 Cornell University Targeting chromosomal instability and downstream cytosolic DNA signaling for cancer treatment
JP7226763B2 (ja) * 2017-08-17 2023-02-21 国立大学法人山口大学 癌幹細胞における薬物耐性の低減剤、癌幹細胞における転移能の抑制剤及び癌の転移性再発リスクを予測する方法
CN114761804A (zh) * 2019-06-21 2022-07-15 艾福姆德尤股份有限公司 治疗癌症的方法
US20230346785A1 (en) * 2020-02-19 2023-11-02 Ibmc - Instituto De Biologia Molecular E Celular 4-PYRROLIDIN-1-Yl-5-P-TOLYL-THIENO[2,3-D] PYRIMIDINE FOR USE IN THE TREATMENT OF AGING-ASSOCIATED AND PREMATURE AGING DISEASES THROUGH RESTORED CHROMOSOMAL STABILITY AND INHIBITION OF CELLULAR SENESCENCE
JP2023534375A (ja) * 2020-05-28 2023-08-09 王 道祥 細胞病理学的サンプルに対する多重染色切片調製法
AU2021336887A1 (en) * 2020-09-02 2023-03-30 Memorial Sloan Kettering Cancer Center Methods and compositions for targeting cytosolic dsDNA signaling in chromosomally unstable cancers
US20240207248A1 (en) * 2021-04-23 2024-06-27 Baruch S. Blumberg Institute Methods, kits and compositions for reducing chromosomal instability in cancer cells
IL310863A (en) 2021-08-26 2024-04-01 Volastra Therapeutics Inc Spiro indoline inhibitors of kif18a
EP4488389A1 (en) * 2023-07-05 2025-01-08 Fundación del Sector Público Estatal Centro Nacional de Investigaciones Oncológicas Carlos III (F.S.P. CNIO) Signature for the prognosis of brain metastasis relapse

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WO2016044790A1 (en) * 2014-09-19 2016-03-24 Memorial Sloan-Kettering Cancer Center Methods for treating brain metastasis
WO2016176222A1 (en) * 2015-04-30 2016-11-03 University Of Washington Cgas in systemic lupus erythematosus (sle)
US20170107577A1 (en) * 2014-03-11 2017-04-20 The Council Of The Queensland Institute Of Medical Research Determining Cancer Aggressiveness, Prognosis and Responsiveness to Treatment

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US6306434B1 (en) 1997-02-12 2001-10-23 Chong Kun Dang Corp. Pharmaceutical composition comprising cyclosporin solid-state microemulsion
GB201121070D0 (en) 2011-12-07 2012-01-18 Isis Innovation composition for delivery of biotherapeutics
EP2934598B1 (en) 2012-12-19 2018-04-18 Board Of Regents, The University Of Texas System Pharmaceutical targeting of a mammalian cyclic di-nucleotide signaling pathway
WO2015036643A2 (es) 2013-09-13 2015-03-19 Sierra Jiménez Angels Marcador para predecir metástasis del cancer de mama
AU2018300007A1 (en) 2017-07-10 2020-02-27 Cornell University Targeting chromosomal instability and downstream cytosolic DNA signaling for cancer treatment

Patent Citations (3)

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US20170107577A1 (en) * 2014-03-11 2017-04-20 The Council Of The Queensland Institute Of Medical Research Determining Cancer Aggressiveness, Prognosis and Responsiveness to Treatment
WO2016044790A1 (en) * 2014-09-19 2016-03-24 Memorial Sloan-Kettering Cancer Center Methods for treating brain metastasis
WO2016176222A1 (en) * 2015-04-30 2016-11-03 University Of Washington Cgas in systemic lupus erythematosus (sle)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109789180A (zh) * 2016-09-02 2019-05-21 伊利诺伊大学理事会 Kif13b衍生的肽和抑制血管生成的方法
CN109789180B (zh) * 2016-09-02 2023-09-08 伊利诺伊大学理事会 Kif13b衍生的肽和抑制血管生成的方法
CN113341154A (zh) * 2021-05-14 2021-09-03 医工瑞思(福建)工程研究中心有限公司 一种检测血栓或凝血相关疾病的生物标志物及其应用
CN115354078A (zh) * 2022-09-02 2022-11-18 中山大学附属第一医院 骨肉瘤检测标记物及其应用

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SG11202000132WA (en) 2020-02-27
CA3069515A1 (en) 2019-01-17
US11821042B2 (en) 2023-11-21
MX2020000406A (es) 2020-10-01
US20240110246A1 (en) 2024-04-04
WO2019014246A1 (en) 2019-01-17
AU2018300007A1 (en) 2020-02-27
EP3652349A1 (en) 2020-05-20
JP7197556B2 (ja) 2022-12-27
BR112020000477A2 (pt) 2020-07-21
US20210130903A1 (en) 2021-05-06
KR20200037796A (ko) 2020-04-09
IL271849A (en) 2020-02-27
JP2020526206A (ja) 2020-08-31

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