CN111202260A - Formula and preparation method of nicotine salt - Google Patents
Formula and preparation method of nicotine salt Download PDFInfo
- Publication number
- CN111202260A CN111202260A CN202010117828.0A CN202010117828A CN111202260A CN 111202260 A CN111202260 A CN 111202260A CN 202010117828 A CN202010117828 A CN 202010117828A CN 111202260 A CN111202260 A CN 111202260A
- Authority
- CN
- China
- Prior art keywords
- parts
- acid
- nicotine
- mixture
- propylene glycol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/10—Chemical features of tobacco products or tobacco substitutes
- A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
- A24B15/167—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes in liquid or vaporisable form, e.g. liquid compositions for electronic cigarettes
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
- A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Manufacture Of Tobacco Products (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention is applicable to the technical field of electronic cigarettes, and provides a formula of nicotine salt and a preparation method thereof, wherein the nicotine salt comprises the following components in parts by weight: citric acid: 2-5 parts; acetic acid: 0.5-1 part; benzoic acid: 20-25 parts; propionic acid: 0.5-1 part; lactic acid: 3-6 parts; malic acid: 3-5 parts; propylene glycol: 31-35 parts; nicotine: 35-38 parts of a solvent; according to the embodiment of the invention, the components are mixed to obtain the nicotine salt which adopts food-grade raw materials, so that the appropriate stimulation can be generated on the throat, the smoking taste and the mouthfeel of the electronic cigarette are well improved, and a user of the electronic cigarette can obtain the satisfaction of smoking a traditional cigarette; meanwhile, perfect and excellent aroma quality is kept, the comfortable taste of the electronic cigarette can be improved, and the user experience effect of the electronic cigarette is good.
Description
Technical Field
The invention belongs to the technical field of electronic cigarettes, and particularly relates to a formula of nicotine salt and a preparation method thereof.
Background
In the prior art, both electronic cigarette manufacturers and consumers want to obtain electronic cigarette oil which has comfortable mouthfeel, is easy to obtain the satisfaction of smoking traditional tobacco and has the taste closer to the traditional tobacco. After the nicotine salt is sold in the market, people find a new direction for research and development. The nicotine salt is expected to be developed to improve the transient stimulation of pure nicotine to the throat, so that the taste of the electronic cigarette is closer to that of the traditional cigarette. Thus, nicotine salts have gained extensive attention and research.
The existing nicotine salt development methods are various, the quality is also different, and the problems that the original fragrance of tobacco tar is influenced due to the fact that the peculiar smell is too heavy when the nicotine salt is used in electronic tobacco tar, the excessive stimulation of nicotine to the throat is not improved and the like generally exist.
Disclosure of Invention
The invention provides a formula of nicotine salt and a preparation method thereof, and aims to solve the problems of heavy peculiar smell and excessive stimulation to throat.
The invention is realized in such a way that a formula of nicotine salt comprises the following components in parts by weight:
citric acid: 2-5 parts;
acetic acid: 0.5-1 part;
benzoic acid: 20-25 parts;
propionic acid: 0.5-1 part;
lactic acid: 3-6 parts;
malic acid: 3-5 parts;
propylene glycol: 31-35 parts;
nicotine: 35-38 parts.
Further, the composition comprises the following components by weight:
the citric acid: 2.5 parts;
the acetic acid: 1 part;
the benzoic acid: 20 parts of (1);
the propionic acid: 0.5 part;
the lactic acid: 3 parts of a mixture;
the malic acid: 5 parts of a mixture;
the propylene glycol: 32 parts of (1);
the nicotine: 36 parts of (A).
Further, the composition comprises the following components by weight:
the citric acid: 2 parts of (1);
the acetic acid: 0.5 part;
the benzoic acid: 24 parts of (1);
the propionic acid: 0.5 part;
the lactic acid: 5 parts of a mixture;
the malic acid: 4 parts of a mixture;
the propylene glycol: 31 parts of (B);
the nicotine: 35 parts of (A).
Further, the composition comprises the following components by weight:
the citric acid: 3 parts of a mixture;
the acetic acid: 0.5 part;
the benzoic acid: 22 parts of (A);
the propionic acid: 0.5 part;
the lactic acid: 5 parts of a mixture;
the malic acid: 3 parts of a mixture;
the propylene glycol: 31 parts of (B);
the nicotine: 35 parts of (A).
Further, the composition comprises the following components by weight:
the citric acid: 3 parts of a mixture;
the acetic acid: 1 part;
the benzoic acid: 22 parts of (A);
the propionic acid: 1 part;
the lactic acid: 3 parts of a mixture;
the malic acid: 3 parts of a mixture;
the propylene glycol: 31 parts of (B);
the nicotine: 35 parts of (A).
Further, the composition comprises the following components by weight:
the citric acid: 2 parts of (1);
the acetic acid: 0.5 part;
the benzoic acid: 20 parts of (1);
the propionic acid: 0.5 part;
the lactic acid: 3 parts of a mixture;
the malic acid: 3 parts of a mixture;
the propylene glycol: 32 parts of (1);
the nicotine: 37 parts of the raw materials.
The invention also provides a preparation method of the nicotine salt, which comprises the following steps:
s1, respectively taking 20-25 parts of benzoic acid, 3-5 parts of malic acid, 31-35 parts of propylene glycol, 35-38 parts of nicotine and 2-5 parts of citric acid for later use;
s2, mixing 20-25 parts of benzoic acid, 3-5 parts of malic acid, 31-35 parts of propylene glycol, 35-38 parts of nicotine and 2-5 parts of citric acid in a container for the first time;
s3, heating and dissolving through water bath;
s4, sequentially adding 0.5-1 part of propionic acid, 3-6 parts of lactic acid and 0.5-1 part of acetic acid into the container, stirring for the second time, and stopping heating after 1-5 minutes;
and S5, taking out the mixture after the second mixing, standing, and cooling to normal temperature to obtain the final product.
Further, in the step S3, the water bath heating temperature is 50-70 ℃.
Further, the step S3 further includes the steps of:
the mixture in the water bath was stirred by a stirrer.
Compared with the prior art, the invention has the following beneficial effects:
the nicotine salt provided by the embodiment of the invention adopts food-grade raw materials, can generate moderate stimulation to the throat, so that the smoking taste and mouthfeel of the electronic cigarette are well improved, and users of the electronic cigarette can obtain satisfaction of smoking traditional cigarettes; meanwhile, perfect and excellent aroma quality is kept, the comfortable taste of the electronic cigarette can be improved, and the user experience effect of the electronic cigarette is good.
Drawings
Fig. 1 is a flow chart of a method for preparing a nicotine salt according to an embodiment of the present invention.
Fig. 2 is table 1 provided by an embodiment of the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is described in further detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
The nicotine salt provided by the embodiment of the invention adopts food-grade raw materials, can generate moderate stimulation to the throat, so that the smoking taste and mouthfeel of the electronic cigarette are well improved, and users of the electronic cigarette can obtain satisfaction of smoking traditional cigarettes; meanwhile, perfect and excellent aroma quality is kept, the comfortable taste of the electronic cigarette can be improved, and the user experience effect of the electronic cigarette is good.
The technical solution and the technical effect of the present invention will be further described by specific examples.
Example one
The invention provides a formula of nicotine salt, which comprises the following components in parts by weight: citric acid: 2-5 parts; acetic acid: 0.5-1 part; benzoic acid: 20-25 parts; propionic acid: 0.5-1 part; lactic acid: 3-6 parts; malic acid: 3-5 parts; propylene glycol: 31-35 parts; nicotine: 35-38 parts.
Among them, citric acid (C6H8O7) is an organic acid, colorless crystal, often contains one molecule of crystal water, is odorless, has strong sour taste, and is easily soluble in water.
Acetic acid (CH3COOH), also called acetic acid and glacial acetic acid, is an organic monobasic acid and is the main component of vinegar.
Benzoic acid (C6H5COOH), also known as benzoic acid, is a compound in which one hydrogen on the phenyl ring is replaced by a carboxyl group (-COOH). Is a scaly or needle crystal having an odor of benzene or formaldehyde at normal temperature.
Propionic acid (CH3CH2COOH), also known as nascent oleic acid, is a three-carbon carboxylic acid, a short chain saturated fatty acid.
Lactic acid (C3H6O3) is a compound that can be optionally mixed with water, ethanol or diethyl ether.
Malic acid (C4H6O5), also known as 2-hydroxysuccinic acid, is white crystal or crystalline powder, has strong hygroscopicity, and is easily soluble in water and ethanol. Has special pleasant sour taste, and malic acid is mainly used in food and pharmaceutical industries.
The propylene glycol has a chemical formula of C3H8O2, is colorless viscous liquid at normal state, is nearly odorless, and smells slightly sweet.
Nicotine (Nicotine), commonly known as Nicotine, is an alkaloid present in plants of the solanaceae family (solanum), and is also an important component of tobacco.
In the specific embodiment, 20-25 parts of benzoic acid, 3-5 parts of malic acid, 31-35 parts of propylene glycol, 35-38 parts of nicotine and 2-5 parts of citric acid are respectively taken for later use; putting 20-25 parts of benzoic acid, 3-5 parts of malic acid, 31-35 parts of propylene glycol, 35-38 parts of nicotine and 2-5 parts of citric acid into a container for first mixing; heating and dissolving the mixture obtained by the first mixing through a water bath; sequentially adding 0.5-1 part of propionic acid, 3-6 parts of lactic acid and 0.5-1 part of acetic acid into a container, stirring for the second mixing, and stopping heating after 1-5 minutes; taking out the mixture after the second mixing, standing, and cooling to normal temperature to obtain the final product.
The nicotine salt provided by the embodiment of the invention adopts food-grade raw materials, can generate moderate stimulation to the throat, so that the smoking taste and mouthfeel of the electronic cigarette are well improved, and users of the electronic cigarette can obtain satisfaction of smoking traditional cigarettes; meanwhile, perfect and excellent aroma quality is kept, the comfortable taste of the electronic cigarette can be improved, and the user experience effect of the electronic cigarette is good.
Example two
In the present embodiment, the following components are included by weight: citric acid: 2.5 parts; acetic acid: 1 part; benzoic acid: 20 parts of (1); propionic acid: 0.5 part; lactic acid: 3 parts of a mixture; malic acid: 5 parts of a mixture; propylene glycol: 32 parts of (1); nicotine: 36 parts of (A).
In the specific embodiment, 20 parts of benzoic acid, 5 parts of malic acid, 32 parts of propylene glycol, 36 parts of nicotine and 2.5 parts of citric acid are respectively taken for standby; 20 parts of benzoic acid, 5 parts of malic acid, 32 parts of propylene glycol, 36 parts of nicotine and 2.5 parts of citric acid are put into a container for first mixing; heating and dissolving the mixture obtained by the first mixing through a water bath; sequentially adding 0.5 part of propionic acid, 3 parts of lactic acid and 1 part of acetic acid into a container, stirring for the second mixing, and stopping heating after 1-5 minutes; taking out the mixture after the second mixing, standing, and cooling to normal temperature to obtain the final product. The nicotine salt adopts food-grade raw materials, can generate moderate stimulation to the throat, so that the smoking taste and mouthfeel of the electronic cigarette are well improved, and users of the electronic cigarette can obtain satisfaction of smoking traditional cigarettes; meanwhile, perfect and excellent aroma quality is kept, the comfortable taste of the electronic cigarette can be improved, and the user experience effect of the electronic cigarette is good.
EXAMPLE III
In the present embodiment, the following components are included by weight: citric acid: 2 parts of (1); acetic acid: 0.5 part; benzoic acid: 24 parts of (1); propionic acid: 0.5 part; lactic acid: 5 parts of a mixture; malic acid: 4 parts of a mixture; propylene glycol: 31 parts of (B); nicotine: 35 parts of (A).
In the specific embodiment, 24 parts of benzoic acid, 4 parts of malic acid, 31 parts of propylene glycol, 35 parts of nicotine and 2 parts of citric acid are respectively taken for standby; putting 24 parts of benzoic acid, 4 parts of malic acid, 31 parts of propylene glycol, 35 parts of nicotine and 2 parts of citric acid into a container for first mixing; heating and dissolving the mixture obtained by the first mixing through a water bath; sequentially adding 0.5 part of propionic acid, 5 parts of lactic acid and 0.5 part of acetic acid into a container, stirring for the second mixing, and stopping heating after 1-5 minutes; taking out the mixture after the second mixing, standing, and cooling to normal temperature to obtain the final product. The nicotine salt adopts food-grade raw materials, can generate moderate stimulation to the throat, so that the smoking taste and mouthfeel of the electronic cigarette are well improved, and users of the electronic cigarette can obtain satisfaction of smoking traditional cigarettes; meanwhile, perfect and excellent aroma quality is kept, the comfortable taste of the electronic cigarette can be improved, and the user experience effect of the electronic cigarette is good.
Example four
In the present embodiment, the following components are included by weight: citric acid: 3 parts of a mixture; acetic acid: 0.5 part; benzoic acid: 22 parts of (A); propionic acid: 0.5 part; lactic acid: 5 parts of a mixture; malic acid: 3 parts of a mixture; propylene glycol: 31 parts of (B); nicotine: 35 parts of (A).
In the specific embodiment, 22 parts of benzoic acid, 3 parts of malic acid, 31 parts of propylene glycol, 35 parts of nicotine and 3 parts of citric acid are respectively taken for standby; placing 22 parts of benzoic acid, 3 parts of malic acid, 31 parts of propylene glycol, 35 parts of nicotine and 3 parts of citric acid into a container for first mixing; heating and dissolving the mixture obtained by the first mixing through a water bath; sequentially adding 0.5 part of propionic acid, 5 parts of lactic acid and 0.5 part of acetic acid into a container, stirring for the second mixing, and stopping heating after 1-5 minutes; taking out the mixture after the second mixing, standing, and cooling to normal temperature to obtain the final product. The nicotine salt adopts food-grade raw materials, can generate moderate stimulation to the throat, so that the smoking taste and mouthfeel of the electronic cigarette are well improved, and users of the electronic cigarette can obtain satisfaction of smoking traditional cigarettes; meanwhile, perfect and excellent aroma quality is kept, the comfortable taste of the electronic cigarette can be improved, and the user experience effect of the electronic cigarette is good.
EXAMPLE five
In the present embodiment, the following components are included by weight: citric acid: 3 parts of a mixture; acetic acid: 1 part; benzoic acid: 22 parts of (A); propionic acid: 1 part; lactic acid: 3 parts of a mixture; malic acid: 3 parts of a mixture; propylene glycol: 31 parts of (B); nicotine: 35 parts of (A).
In the specific embodiment, 22 parts of benzoic acid, 3 parts of malic acid, 31 parts of propylene glycol, 35 parts of nicotine and 3 parts of citric acid are respectively taken for standby; placing 22 parts of benzoic acid, 3 parts of malic acid, 31 parts of propylene glycol, 35 parts of nicotine and 3 parts of citric acid into a container for first mixing; heating and dissolving the mixture obtained by the first mixing through a water bath; sequentially adding 1 part of propionic acid, 3 parts of lactic acid and 1 part of acetic acid into a container, stirring for the second mixing, and stopping heating after 1-5 minutes; taking out the mixture after the second mixing, standing, and cooling to normal temperature to obtain the final product. The nicotine salt adopts food-grade raw materials, can generate moderate stimulation to the throat, so that the smoking taste and mouthfeel of the electronic cigarette are well improved, and users of the electronic cigarette can obtain satisfaction of smoking traditional cigarettes; meanwhile, perfect and excellent aroma quality is kept, the comfortable taste of the electronic cigarette can be improved, and the user experience effect of the electronic cigarette is good.
EXAMPLE six
In the present embodiment, the following components are included by weight: citric acid: 2 parts of (1); acetic acid: 0.5 part; benzoic acid: 20 parts of (1); propionic acid: 0.5 part; lactic acid: 3 parts of a mixture; malic acid: 3 parts of a mixture; propylene glycol: 32 parts of (1); nicotine: 37 parts of the raw materials.
In the specific embodiment, 20 parts of benzoic acid, 3 parts of malic acid, 31 parts of propylene glycol, 37 parts of nicotine and 2 parts of citric acid are respectively taken for standby; 20 parts of benzoic acid, 3 parts of malic acid, 31 parts of propylene glycol, 37 parts of nicotine and 2 parts of citric acid are put into a container to be mixed for the first time; heating and dissolving the mixture obtained by the first mixing through a water bath; sequentially adding 0.5 part of propionic acid, 3 parts of lactic acid and 0.5 part of acetic acid into a container, stirring for the second mixing, and stopping heating after 1-5 minutes; taking out the mixture after the second mixing, standing, and cooling to normal temperature to obtain the final product. The nicotine salt adopts food-grade raw materials, can generate moderate stimulation to the throat, so that the smoking taste and mouthfeel of the electronic cigarette are well improved, and users of the electronic cigarette can obtain satisfaction of smoking traditional cigarettes; meanwhile, perfect and excellent aroma quality is kept, the comfortable taste of the electronic cigarette can be improved, and the user experience effect of the electronic cigarette is good.
EXAMPLE seven
With reference to fig. 1, the present invention further provides a method for preparing a nicotine salt, comprising the steps of:
s1, respectively taking 20-25 parts of benzoic acid, 3-5 parts of malic acid, 31-35 parts of propylene glycol, 35-38 parts of nicotine and 2-5 parts of citric acid for later use.
Specifically, 20-25 parts of benzoic acid, 3-5 parts of malic acid, 31-35 parts of propylene glycol, 35-38 parts of nicotine and 2-5 parts of citric acid are respectively put into correspondingly numbered containers for standby, so that convenience in measuring the components is guaranteed, component confusion is avoided, and safety is high.
Wherein, the container for holding the components is clean, which can effectively ensure the purity of the benzoic acid, the malic acid, the propylene glycol, the nicotine and the citric acid and avoid the contamination or the pollution caused by the external unfavorable components.
S2, mixing 20-25 parts of benzoic acid, 3-5 parts of malic acid, 31-35 parts of propylene glycol, 35-38 parts of nicotine and 2-5 parts of citric acid in a container for the first time.
Specifically, the benzoic acid, the malic acid, the propylene glycol, the nicotine and the citric acid of the components are poured into a container to be mixed, and the mixture of the benzoic acid, the malic acid, the propylene glycol, the nicotine and the citric acid is stirred by a stirring device (such as a stirrer), so that the mixing efficiency of the mixture is accelerated, the mixing effect of the mixture can be improved, and the mixture is uniformly mixed under the stirring of the stirrer.
And S3, heating and dissolving through a water bath.
Specifically, the mixture of benzoic acid, malic acid, propylene glycol, nicotine and citric acid can be dissolved quickly by heating the mixture in water bath. Since benzoic acid, malic acid, propylene glycol, nicotine and citric acid can be mutually dissolved, the dissolving efficiency is continuously improved along with the temperature rise in the water bath, but the water bath temperature is not too high, otherwise, the molecules of benzoic acid, malic acid, propylene glycol, nicotine and citric acid are destroyed, and the dissolving effect of the mixture is influenced.
S4, sequentially adding 0.5-1 part of propionic acid, 3-6 parts of lactic acid and 0.5-1 part of acetic acid into the container, stirring for the second time, and stopping heating after 1-5 minutes.
Specifically, after the mixture of the benzoic acid, the malic acid, the propylene glycol, the nicotine and the citric acid which are mixed for the first time is heated and dissolved in a certain water bath, the propionic acid, the lactic acid and the acetic acid which are prepared from the components are sequentially added into a container for containing the mixture, and the mixture is stirred for the second time, so that the propionic acid, the lactic acid and the acetic acid can be mixed with the mixture of the benzoic acid, the malic acid, the propylene glycol, the nicotine and the citric acid better in mixing effect, the reaction effect of the components is good, and the nicotine salt generation efficiency is high. The water bath heating is stopped after 1-5 minutes, so that the nicotine salt is prevented from being further dissolved in a long-time high-temperature environment, and the collection of the nicotine salt is prevented from being influenced.
Preferably, 0.5-1 part of propionic acid, 3-6 parts of lactic acid and 0.5-1 part of acetic acid are sequentially added into the container to be stirred for the second mixing, and the heating is stopped after 2 minutes, so that the effect is better, the time is proper, and the production efficiency is high.
Preferably, the second mixing is carried out by adding 0.5-1 part of propionic acid, 3-6 parts of lactic acid and 0.5-1 part of acetic acid in sequence into the vessel and stirring, and after the second mixing is carried out uniformly, the heating is stopped after 3 minutes.
And S5, taking out the mixture after the second mixing, standing, and cooling to normal temperature to obtain the final product.
Specifically, in order to accelerate the dissolving efficiency of the mixture of benzoic acid, malic acid, propylene glycol, nicotine and citric acid, the temperature in the container can be effectively ensured to be uniform through water bath heating, and the dissolving effect is good. And in the second mixing, propionic acid, lactic acid and acetic acid are added into the first mixture in sequence for mixing treatment, and the mixing efficiency is accelerated by stirring through a stirrer in the mixing process. In this case, since the mixture after the second mixing is still at the temperature at the time of the first mixing, it is necessary to cool the second mixture, and the nicotine salt can be obtained by taking out the mixture after the second mixing from the container, leaving it for a certain period of time (for example, 5 to 15 minutes), and cooling it to room temperature. The nicotine salt adopts food-grade raw materials, can generate moderate stimulation to the throat, so that the smoking taste and mouthfeel of the electronic cigarette are well improved, and users of the electronic cigarette can obtain satisfaction of smoking traditional cigarettes; meanwhile, perfect and excellent aroma quality is kept, the comfortable taste of the electronic cigarette can be improved, and the user experience effect of the electronic cigarette is good.
In this embodiment, in the step S3, the water bath heating temperature is 50-70 ℃.
Specifically, as the dissolving temperature of the benzoic acid, the malic acid, the propylene glycol, the nicotine and the citric acid cannot be too high, the mixture of the benzoic acid, the malic acid, the propylene glycol, the nicotine and the citric acid is heated in a water bath at the temperature of 50-70 ℃, the dissolving effect is good, and meanwhile, the substances of the mixture of the benzoic acid, the malic acid, the propylene glycol, the nicotine and the citric acid cannot be damaged, and the safety is high.
Preferably, the mixture has good dissolving effect at the water bath temperature of 60 ℃, thereby improving the production efficiency of the nicotine salt.
Of course, the dissolution of the mixture was equally good at water bath temperatures of 50 deg.C, 55 deg.C, 65 deg.C and 70 deg.C. Therefore, a description thereof will not be repeated here.
In this embodiment, the step S3 further includes the steps of: the mixture in the water bath was stirred by a stirrer.
Wherein the stirrer comprises a flap stirrer, a frame stirrer and the like.
The flap type stirrer can enable materials to circularly flow in the reaction kettle during stirring, plays a role of mainly volume circulation, has small shearing action and has good up-and-down turning effect. When a larger flow velocity is needed, a guide cylinder is arranged in the reaction kettle. The flap turbine stirrer is generally suitable for the reaction of gas-liquid phase mixing, and the rotation number of the stirrer is generally selected to be more than 300 r/min.
The frame stirrer can be regarded as a paddle stirrer, and has a firmer structure and large material stirring amount. If the shape of the bottom of the stirrer is similar to that of the bottom head of the reaction kettle, the stirrer is generally called an anchor stirrer. The gap between the frame type stirrer and the kettle wall is small, which is beneficial to the heat transfer process, and when the frame type stirrer rotates rapidly, the static layer is taken down from the wall of the reaction kettle by the liquid driven by the blades of the stirrer; the agitator with the scraper plate can produce good heat conduction when rotating at a slow speed. Such agitators are commonly used for heat transfer, crystallization operations, and agitation of high viscosity liquids, high consistency slurries, and settling slurries.
Specifically, the mixture in the water bath is stirred by the stirrer, so that the dissolving efficiency of the mixture of benzoic acid, malic acid, propylene glycol, nicotine and citric acid can be improved, and the use is wide.
Of course, the stirring process of the present invention is used to accelerate the dissolution efficiency of the mixture of benzoic acid, malic acid, propylene glycol, nicotine and citric acid. Not only can only use a stirrer, but also can use manual stirring, a stirring rod and the like.
To further illustrate the beneficial effects of the nicotine salts provided by the embodiments of the present invention, further detailed descriptions are provided below with reference to specific test examples:
test one: odor test
1. Test samples: embodiments one through six of the present invention provide nicotine salt products prepared from the components.
2. Preparation of test solutions: the sensory quality evaluation was carried out by weighing 20 g of the nicotine salt products provided in examples one to six to electronic smoking sets (using more than two brands) numbered 1-30 respectively, wherein the electronic smoking sets used in the test of the invention are common electronic smoking sets on the market, the power is 8-10W, and the voltage is 3.3-4.2V. Taking out 0.6g of nicotine salt, 15g of essence and flavor, 34.4g of propylene glycol and 50g of glycerol, accurately weighing the components (within an error of 2%), and placing the components in a container to be fully and uniformly stirred to obtain the tobacco tar with the added compound nicotine salt.
And (3) formal test: the tobacco tar is injected into an electronic cigarette atomizer with the same power for 30 electronic cigarette fans to try, and the tobacco tar is compared and evaluated with the tobacco tar with the same taste and the same content of nicotine. In the test, the user inhales according to the common smoking habit, sufficient amount of the inhaled air is inhaled, and then the inhaled atomized steam is returned to the pharynx in a smooth manner, and is exhaled slowly from the nasal cavity. In 30 experiments, 27 people react to the tobacco tar containing the composite nicotine salt to have no peculiar smell brought by nicotine, and 3 people feel that no remarkable effect is felt, so that the composite nicotine salt has a remarkable improvement effect on the peculiar smell of the tobacco tar and does not bring the peculiar smell to influence the original fragrance of the tobacco tar.
Wherein, 27 people react the tobacco tar containing the compound nicotine salt to have comfortable taste and proper stimulation to the throat, and can not feel the peculiar smell brought by the nicotine; 3 felt that no significant effect was perceived. The composite nicotine salt has obvious effect of improving the taste of the tobacco tar, and does not bring peculiar smell to influence the original fragrance of the tobacco tar.
And (2) test II: comfort test
1. Test samples: embodiments one through six of the present invention provide nicotine salt products prepared from the components.
2. Preparation of test solutions: the sensory quality evaluation was carried out by weighing 20 g of the nicotine salt products provided in examples one to six to electronic smoking sets (using more than two brands) numbered 1-30 respectively, wherein the electronic smoking sets used in the test of the invention are common electronic smoking sets on the market, the power is 8-10W, and the voltage is 3.3-4.2V. Taking out 0.6g of nicotine salt, 15g of essence and flavor, 34.4g of propylene glycol and 50g of glycerol, accurately weighing the components (within an error of 2%), and placing the components in a container to be fully and uniformly stirred to obtain the tobacco tar with the added compound nicotine salt.
And (3) formal test: the tobacco tar is injected into an electronic cigarette atomizer with the same power for 30 electronic cigarette fans to try, and the tobacco tar is compared and evaluated with the tobacco tar with the same taste and the same content of nicotine. In the test, the user inhales according to the common smoking habit, sufficient amount of the inhaled air is inhaled, and then the inhaled atomized steam is returned to the pharynx in a smooth manner, and is exhaled slowly from the nasal cavity. In 30 experiments, among them, 28 persons responded that the tobacco tar containing the composite nicotine salt had comfortable mouth feel and appropriate throat irritation, and 2 persons felt no significant effect, so that the composite nicotine salt had significant improvement effect on the mouth feel of the tobacco tar.
And (3) test III: taste style
1. Test samples: embodiments one through six of the present invention provide nicotine salt products prepared from the components.
2. Preparation of test solutions: the sensory quality evaluation was carried out by weighing 20 g of the nicotine salt products provided in examples one to six to electronic smoking sets (using more than two brands) numbered 1-30 respectively, wherein the electronic smoking sets used in the test of the invention are common electronic smoking sets on the market, the power is 8-10W, and the voltage is 3.3-4.2V. Taking out 0.6g of nicotine salt, 15g of essence and flavor, 34.4g of propylene glycol and 50g of glycerol, accurately weighing the components (within an error of 2%), and placing the components in a container to be fully and uniformly stirred to obtain the tobacco tar with the added compound nicotine salt.
And (3) formal test: the tobacco tar is injected into an electronic cigarette atomizer with the same power for 30 electronic cigarette fans to try, and the tobacco tar is compared and evaluated with the tobacco tar with the same taste and the same content of nicotine. In the test, the user inhales according to the common smoking habit, sufficient amount of the inhaled air is inhaled, and then the inhaled atomized steam is returned to the pharynx in a smooth manner, and is exhaled slowly from the nasal cavity. In 30 experiments, 29 of the experiments have slightly sweet aftertaste and complete fragrance, and are not dry and moist; the exhaled aroma of 1 case was slightly impure. The effect of keeping the fragrance of the electronic cigarette complete is basically achieved.
As shown in fig. 2, table 1 shows the results of smoking evaluation of the electronic cigarette liquid according to the embodiment of the present invention.
TABLE 1
In summary, the nicotine salt prepared in the first to sixth embodiments of the present invention has an important effect on the quality due to the taste and mouthfeel of the electronic cigarette, and also directly affects the product popularization and sale. The excellent nicotine salt with good quality generates moderate stimulation to the throat, so that the smoking taste and the mouth feel of the electronic cigarette are well improved, and users of the electronic cigarette can obtain satisfaction of smoking traditional cigarettes. In addition to a perfect and excellent aroma quality, a pleasant mouthfeel is more desirable to set off regardless of the flavor of the tobacco oil. The nicotine salt adopts food-grade raw materials, can generate moderate stimulation to the throat, so that the smoking taste and mouthfeel of the electronic cigarette are well improved, and users of the electronic cigarette can obtain satisfaction of smoking traditional cigarettes; meanwhile, perfect and excellent aroma quality is kept, the comfortable taste of the electronic cigarette can be improved, and the user experience effect of the electronic cigarette is good.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents and improvements made within the spirit and principle of the present invention are intended to be included within the scope of the present invention.
Claims (9)
1. The formula of the nicotine salt is characterized by comprising the following components in parts by weight:
citric acid: 2-5 parts;
acetic acid: 0.5-1 part;
benzoic acid: 20-25 parts;
propionic acid: 0.5-1 part;
lactic acid: 3-6 parts;
malic acid: 3-5 parts;
propylene glycol: 31-35 parts;
nicotine: 35-38 parts.
2. The formulation of nicotine salt of claim 1, comprising, by weight:
the citric acid: 2.5 parts;
the acetic acid: 1 part;
the benzoic acid: 20 parts of (1);
the propionic acid: 0.5 part;
the lactic acid: 3 parts of a mixture;
the malic acid: 5 parts of a mixture;
the propylene glycol: 32 parts of (1);
the nicotine: 36 parts of (A).
3. The formulation of nicotine salt of claim 1, comprising, by weight:
the citric acid: 2 parts of (1);
the acetic acid: 0.5 part;
the benzoic acid: 24 parts of (1);
the propionic acid: 0.5 part;
the lactic acid: 5 parts of a mixture;
the malic acid: 4 parts of a mixture;
the propylene glycol: 31 parts of (B);
the nicotine: 35 parts of (A).
4. The formulation of nicotine salt of claim 1, comprising, by weight:
the citric acid: 3 parts of a mixture;
the acetic acid: 0.5 part;
the benzoic acid: 22 parts of (A);
the propionic acid: 0.5 part;
the lactic acid: 5 parts of a mixture;
the malic acid: 3 parts of a mixture;
the propylene glycol: 31 parts of (B);
the nicotine: 35 parts of (A).
5. The formulation of nicotine salt of claim 1, comprising, by weight:
the citric acid: 3 parts of a mixture;
the acetic acid: 1 part;
the benzoic acid: 22 parts of (A);
the propionic acid: 1 part;
the lactic acid: 3 parts of a mixture;
the malic acid: 3 parts of a mixture;
the propylene glycol: 31 parts of (B);
the nicotine: 35 parts of (A).
6. The formulation of nicotine salt of claim 1, comprising, by weight:
the citric acid: 2 parts of (1);
the acetic acid: 0.5 part;
the benzoic acid: 20 parts of (1);
the propionic acid: 0.5 part;
the lactic acid: 3 parts of a mixture;
the malic acid: 3 parts of a mixture;
the propylene glycol: 32 parts of (1);
the nicotine: 37 parts of the raw materials.
7. A method of preparing a nicotine salt, comprising the steps of:
s1, respectively taking 20-25 parts of benzoic acid, 3-5 parts of malic acid, 31-35 parts of propylene glycol, 35-38 parts of nicotine and 2-5 parts of citric acid for later use;
s2, mixing 20-25 parts of benzoic acid, 3-5 parts of malic acid, 31-35 parts of propylene glycol, 35-38 parts of nicotine and 2-5 parts of citric acid in a container for the first time;
s3, heating and dissolving through water bath;
s4, sequentially adding 0.5-1 part of propionic acid, 3-6 parts of lactic acid and 0.5-1 part of acetic acid into the container, stirring for the second time, and stopping heating after 1-5 minutes;
and S5, taking out the mixture after the second mixing, standing, and cooling to normal temperature to obtain the final product.
8. The method for preparing a nicotine salt according to claim 7, wherein the water bath heating temperature is 50 to 70 ℃ in the step S3.
9. The method for preparing a nicotine salt according to claim 7, further comprising the step of:
the mixture in the water bath was stirred by a stirrer.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010117828.0A CN111202260A (en) | 2020-02-25 | 2020-02-25 | Formula and preparation method of nicotine salt |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010117828.0A CN111202260A (en) | 2020-02-25 | 2020-02-25 | Formula and preparation method of nicotine salt |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN111202260A true CN111202260A (en) | 2020-05-29 |
Family
ID=70783660
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010117828.0A Pending CN111202260A (en) | 2020-02-25 | 2020-02-25 | Formula and preparation method of nicotine salt |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN111202260A (en) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112851636A (en) * | 2021-01-20 | 2021-05-28 | 深圳市艾普生物科技有限公司 | Preparation method and application of synthetic nicotine salt |
| CN113208156A (en) * | 2021-05-07 | 2021-08-06 | 云南中烟工业有限责任公司 | Fragrance-carrying supramolecular gel based on citric acid nicotine salt gelling agent |
| CN113545510A (en) * | 2021-06-17 | 2021-10-26 | 深圳市博睿生物科技有限公司 | Nicotine salt, preparation method and application |
| CN113812665A (en) * | 2021-10-08 | 2021-12-21 | 云南巴菰生物科技股份有限公司 | Electronic cigarette atomized liquid containing betelnut citrate salt and preparation method thereof |
| CN114343229A (en) * | 2022-01-24 | 2022-04-15 | 深圳市真味生物科技有限公司 | Preparation method of novel nicotine salt |
| CN114642271A (en) * | 2020-12-17 | 2022-06-21 | N·K·帕特尔 | Nicotine pouch |
| CN116965584A (en) * | 2023-08-11 | 2023-10-31 | 东莞市吉纯生物技术有限公司 | Electronic atomized liquid nicotine salt with strong aroma type tobacco taste |
| CN117158635A (en) * | 2023-10-16 | 2023-12-05 | 东莞市吉纯生物技术有限公司 | Sour composition, sour agent for atomized liquid and application of sour agent |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107536099A (en) * | 2017-09-14 | 2018-01-05 | 昌宁德康生物科技（深圳）有限公司 | A kind of nicotine salt and preparation method thereof |
| CN109007981A (en) * | 2018-09-10 | 2018-12-18 | 深圳市新宜康科技股份有限公司 | A kind of liquid nicotine salt and preparation method thereof |
| CN109619655A (en) * | 2019-01-18 | 2019-04-16 | 深圳市同信兴投资有限公司 | A kind of compound nicotine salt and its solution, preparation method and application |
| CN110150760A (en) * | 2019-05-31 | 2019-08-23 | 钟术光 | A kind of aerosol generation system |
-
2020
- 2020-02-25 CN CN202010117828.0A patent/CN111202260A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107536099A (en) * | 2017-09-14 | 2018-01-05 | 昌宁德康生物科技（深圳）有限公司 | A kind of nicotine salt and preparation method thereof |
| CN109007981A (en) * | 2018-09-10 | 2018-12-18 | 深圳市新宜康科技股份有限公司 | A kind of liquid nicotine salt and preparation method thereof |
| CN109619655A (en) * | 2019-01-18 | 2019-04-16 | 深圳市同信兴投资有限公司 | A kind of compound nicotine salt and its solution, preparation method and application |
| CN110150760A (en) * | 2019-05-31 | 2019-08-23 | 钟术光 | A kind of aerosol generation system |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114642271A (en) * | 2020-12-17 | 2022-06-21 | N·K·帕特尔 | Nicotine pouch |
| CN112851636A (en) * | 2021-01-20 | 2021-05-28 | 深圳市艾普生物科技有限公司 | Preparation method and application of synthetic nicotine salt |
| WO2022156268A1 (en) * | 2021-01-20 | 2022-07-28 | 深圳市艾普生物科技有限公司 | Preparation method for and use of synthetic nicotine salt |
| CN113208156A (en) * | 2021-05-07 | 2021-08-06 | 云南中烟工业有限责任公司 | Fragrance-carrying supramolecular gel based on citric acid nicotine salt gelling agent |
| CN113545510A (en) * | 2021-06-17 | 2021-10-26 | 深圳市博睿生物科技有限公司 | Nicotine salt, preparation method and application |
| CN113812665A (en) * | 2021-10-08 | 2021-12-21 | 云南巴菰生物科技股份有限公司 | Electronic cigarette atomized liquid containing betelnut citrate salt and preparation method thereof |
| CN113812665B (en) * | 2021-10-08 | 2022-07-08 | 云南巴菰生物科技股份有限公司 | Electronic cigarette atomized liquid containing betelnut citrate salt and preparation method thereof |
| CN114343229A (en) * | 2022-01-24 | 2022-04-15 | 深圳市真味生物科技有限公司 | Preparation method of novel nicotine salt |
| CN116965584A (en) * | 2023-08-11 | 2023-10-31 | 东莞市吉纯生物技术有限公司 | Electronic atomized liquid nicotine salt with strong aroma type tobacco taste |
| CN117158635A (en) * | 2023-10-16 | 2023-12-05 | 东莞市吉纯生物技术有限公司 | Sour composition, sour agent for atomized liquid and application of sour agent |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN111202260A (en) | Formula and preparation method of nicotine salt | |
| CN105595417B (en) | Linear composite gel fragrance controlled-release filter stick and preparation method and application thereof | |
| WO2023137837A1 (en) | Electronic atomized liquid, novel nicotine salt and preparation method therefor | |
| CN111671130A (en) | Electronic cigarette oil with betel nut effect and preparation method thereof | |
| CN108285441A (en) | A kind of nicotine-mandelate compound crystal, preparation method and the tobacco product comprising it | |
| CN106615219B (en) | A method of preparing trans-fatty acid-free plant fat cream | |
| CN110129152B (en) | Beer with pepper flavor | |
| CN114868955A (en) | Preparation method of nicotine salt, nicotine salt and aerosol product | |
| CN101573099A (en) | Cooling agent composition and preparative method thereof | |
| CN109170811A (en) | A kind of novel rattan green pepper sauce and preparation method thereof | |
| CN114983001A (en) | Additive for tobacco products, preparation method and application thereof | |
| JP2021534812A (en) | Composition | |
| CN105795515A (en) | Preparation method of cigarette tip rod with supramolecular controlled-release cool essence | |
| CN105124752A (en) | Peppermint oil based nano-emulsion for cigarettes and preparation method and application of peppermint oil based nano-emulsion | |
| CN107760491A (en) | It is a kind of can toxin expelling detumescence whitening matrimony vine peach gum adlay soap of Chinese medicine preparation method | |
| CN114403494A (en) | Electronic cigarette oil without nicotine and preparation method thereof | |
| CN106262580A (en) | A kind of coolant agent N (4 methoxyphenyl) using method to menthyl 3 carboxylic acid amides | |
| JPH0728657B2 (en) | Whipped yogurt manufacturing method | |
| CN111202259A (en) | Smoke-free electronic cigarette liquid and preparation method thereof | |
| CN108887652A (en) | A kind of sour milk essence of shaddock and its preparation method and application | |
| CN106561963B (en) | Chewing gum containing gelatin-octenyl succinic acid starch ester-L-menthol microcapsule and preparation method thereof | |
| CN103859064B (en) | Blend cooking oil containing peony seed oil and preparation method of blend cooking oil | |
| CN109864331A (en) | A kind of cigarette flavors additive and preparation method thereof | |
| CN108606360A (en) | A kind of application of two esters tobacco aromaticss in cigarette | |
| CN109207257A (en) | A kind of perfume flavouring essence for tobacco |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20200529 |
|
| WD01 | Invention patent application deemed withdrawn after publication |