CN111184670B - Cosmetic emulsion containing nanogold component and preparation method thereof - Google Patents
Cosmetic emulsion containing nanogold component and preparation method thereof Download PDFInfo
- Publication number
- CN111184670B CN111184670B CN202010155197.1A CN202010155197A CN111184670B CN 111184670 B CN111184670 B CN 111184670B CN 202010155197 A CN202010155197 A CN 202010155197A CN 111184670 B CN111184670 B CN 111184670B
- Authority
- CN
- China
- Prior art keywords
- solution
- mass concentration
- nanogold
- adding mass
- emulsion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/736—Chitin; Chitosan; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Dispersion Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Emergency Medicine (AREA)
- Cosmetics (AREA)
Abstract
The cosmetic emulsion provided by the invention combines the snowflake-shaped nanogold with the moisturizing component and the antibacterial and anti-inflammatory component, wherein the nanogold has a good antioxidant function, can effectively remove hydroxyl free radicals to promote human epidermal cell proliferation and has an anti-aging function, the thermal and kinetic factors of the reaction are controlled under a sealed hydrothermal condition in a dynamic nucleation and crystallization mode, and finally the snowflake-shaped Au nanoparticles are obtained, and the snowflake-shaped nanogold-shaped gold has more surface step atoms and high active site density and can effectively reduce the cost.
Description
Technical Field
The invention relates to the field of daily fine chemical products, in particular to a cosmetic emulsion containing a nano-gold component.
Background
With the development of society and the continuous improvement of living standard of people, the cosmetic industry in China is in the rapid development period, and meanwhile, the continuous research and development of cosmetic types are promoted to meet the needs of people. The cosmetics can be further divided into different types of cosmetics for infants, cosmetics for juveniles, cosmetics for men, cosmetics for pregnant women and the like according to objects, and are mainly divided into cosmetic varieties with different effects of whitening, moisturizing, wrinkle resistance, aging resistance and the like according to purposes.
Electronic equipment in daily life is used more and more frequently, skin is known to be exposed to blue light and high-energy environment for a long time to accelerate skin aging and wrinkle growth, until now, coenzyme Q10 which is a main component of antioxidation basically plays a role once, namely, the coenzyme Q10 loses efficacy once entering the body and has 7 active oxygen, and the coenzyme Q10 and other components can only remove one active oxygen, so that some research and development personnel apply nanogold to cosmetics, can enter the deep layer of the skin, can not only activate cells, but also eliminate free radicals and resist oxidation, however, the addition of gold can cause the cost of the cosmetics to be increased.
The shape of the nano Au is an important factor influencing the physicochemical property of the Au, the Au is prepared into nano particles, the proportion of surface atoms is greatly improved, the specific surface area is greatly increased, and the distribution and arrangement of the Au surface atoms with different shapes are different. Therefore, by using the shape control synthesis technology, the Au nano material with a specific shape can be prepared by a simple method and applied to cosmetics to improve the utilization efficiency of the nano gold and reduce the cost of the emulsion, and the method has important application value and practical significance.
Disclosure of Invention
Based on the consideration, the technical problem to be solved by the invention is to provide a cosmetic emulsion containing nanogold, which improves the utilization efficiency of Au nanoparticles by changing the shape of the Au nanoparticles, reduces the use amount of Au and reduces the cost.
The invention relates to a preparation method of a cosmetic emulsion containing nanogold, which comprises the following steps:
(1) preparing a hyaluronic acid aqueous solution, adding the prepared nano gold sol, and performing ultrasonic treatment until the solution is uniform to obtain a solution A;
(2) adding a certain amount of plant extract and rose essential oil into deionized water, and stirring until the plant extract and the rose essential oil are completely dissolved to obtain a solution B;
(3) adding chitosan into butanediol and ethylhexylglycerin, and uniformly mixing to obtain a solution C;
(4) preparing emulsion by a microfluidic technology, respectively injecting the solution A, B, C into the first flow channel, the second flow channel and the third flow channel, and fully colliding and shearing media in the flow channels at the intersection of the flow channels to obtain the emulsion.
Preferably, the mass concentration of the added nano gold is 0.01-0.05% and the mass concentration of the added hyaluronic acid is 0.3-1% based on the prepared emulsion.
Preferably, the mass concentration of the added plant extract is 2-8% and the mass concentration of the added rose essential oil is 1-3% based on the prepared emulsion.
Preferably, based on the emulsion obtained, the addition mass concentration of chitosan is 0.5% -2%, the addition mass concentration of butanediol is 5% -10%, and the addition mass concentration of ethylhexyl glycerol is 5% -10%.
Preferably, the plant extract is selected from grape seed extract and/or chamomile extract.
Preferably, the preparation steps of the nanogold sol are as follows:
A. weighing 60mg of PVP, 180mg of trisodium citrate (Na3C6HSO7) and 30mg of NaBr in a 20ml hydrothermal reaction kettle;
B. adding 0.6g of 20mM NaAuCl4 aqueous solution into a hydrothermal reaction kettle, measuring 8ml of deionized water into the hydrothermal reaction kettle, and magnetically stirring for 15min at room temperature;
C. and C, heating the reaction kettle in the step B to 160 ℃ by a program, reacting the reaction solution for 6 hours at a constant temperature under a magnetic stirring state of 800r/min, finishing the reaction, and cooling to room temperature to obtain the snowflake-shaped nanogold sol.
The invention has the beneficial effects that: the cosmetic emulsion provided by the invention combines the snowflake-shaped nanogold with the moisturizing component and the antibacterial and anti-inflammatory component, wherein the nanogold has a good antioxidant function, can effectively remove hydroxyl free radicals to promote the proliferation of epidermal cells of a human body and has an anti-aging function, the snowflake-shaped nanogold-shaped gold has more surface step atoms, the active site density is high, and the cost can be effectively reduced.
Drawings
FIG. 1 is an XRD spectrum of snowflake Au nanoparticles prepared;
FIG. 2 is an XPS spectrum of snowflake Au nanoparticles prepared in example 1;
FIG. 3 is a TEM spectrum of Au nanoparticles prepared in comparative example 1;
fig. 4 is a TEM spectrum of Au nanoparticles prepared in comparative example 2.
Detailed Description
The following detailed description is made with reference to the accompanying drawings.
Example 1
A method for preparing cosmetic emulsion containing nanogold comprises the following steps:
(1) preparing a hyaluronic acid aqueous solution, adding the prepared nano gold sol, and performing ultrasonic treatment until the solution is uniform to obtain a solution A;
(2) adding a certain amount of plant extract and rose essential oil into deionized water, and stirring until the plant extract and the rose essential oil are completely dissolved to obtain a solution B;
(3) adding chitosan into butanediol and ethylhexylglycerin, and uniformly mixing to obtain a solution C;
(4) preparing emulsion by a microfluidic technology, respectively injecting the solution A, B, C into the first flow channel, the second flow channel and the third flow channel, and fully colliding and shearing media in the flow channels at the intersection of the flow channels to obtain the emulsion.
Based on the prepared emulsion, the adding mass concentration of the nano gold is 0.02%, and the adding mass concentration of the hyaluronic acid is 0.8%.
Based on the prepared emulsion, the adding mass concentration of the plant extract is 7%, and the adding mass concentration of the rose essential oil is 2%.
Based on the prepared emulsion, the adding mass concentration of the chitosan is 1%, the adding mass concentration of the butanediol is 9%, and the adding mass concentration of the ethylhexyl glycerin is 5%.
The plant extractive solution is selected from grape seed extract.
The preparation steps of the nano gold sol are as follows:
A. weighing 60mg of PVP, 180mg of trisodium citrate (Na3C6HSO7) and 30mg of NaBr in a 20ml hydrothermal reaction kettle;
B. adding 0.6g of 20mM NaAuCl4 aqueous solution into a hydrothermal reaction kettle, measuring 8ml of deionized water into the hydrothermal reaction kettle, and magnetically stirring for 15min at room temperature;
C. and (3) heating the reaction kettle in the step (B) to 160 ℃, reacting the reaction solution for 6 hours at constant temperature under the magnetic stirring state of 800r/min, finishing the reaction, and cooling to room temperature to obtain snowflake-shaped nanogold (shown in figure 1) sol.
Comparative example 1
A method for preparing cosmetic emulsion containing nanogold comprises the following steps:
(1) preparing a hyaluronic acid aqueous solution, adding the prepared nano gold sol, and performing ultrasonic treatment until the solution is uniform to obtain a solution A;
(2) adding a certain amount of plant extract and rose essential oil into deionized water, and stirring until the plant extract and the rose essential oil are completely dissolved to obtain a solution B;
(3) adding chitosan into butanediol and ethylhexylglycerin, and uniformly mixing to obtain a solution C;
(4) preparing emulsion by a microfluidic technology, respectively injecting the solution A, B, C into the first flow channel, the second flow channel and the third flow channel, and fully colliding and shearing media in the flow channels at the intersection of the flow channels to obtain the emulsion.
Based on the prepared emulsion, the adding mass concentration of the nano gold is 0.02%, and the adding mass concentration of the hyaluronic acid is 0.8%.
Based on the prepared emulsion, the adding mass concentration of the plant extract is 7%, and the adding mass concentration of the rose essential oil is 2%.
Based on the prepared emulsion, the adding mass concentration of the chitosan is 1%, the adding mass concentration of the butanediol is 9%, and the adding mass concentration of the ethylhexyl glycerin is 5%.
The plant extractive solution is selected from grape seed extract.
The preparation steps of the nano gold sol are as follows:
A. 60mg PVP, 180mg trisodium citrate (Na) are weighed out3C6HSO7) In a 20ml hydrothermal reaction kettle;
B. 0.6g of 20mM NaAuCl was added4Putting the aqueous solution into a hydrothermal reaction kettle, then measuring 8ml of deionized water into the hydrothermal reaction kettle, and magnetically stirring for 15min at room temperature;
C. and C, heating the reaction kettle in the step B to 160 ℃ by a program, reacting the reaction solution for 6 hours at a constant temperature under a magnetic stirring state of 800r/min, finishing the reaction, and cooling to room temperature to obtain Au nano (shown in figure 3) sol.
Comparative example 2
A method for preparing cosmetic emulsion containing nanogold comprises the following steps:
(1) preparing a hyaluronic acid aqueous solution, adding the prepared nano gold sol, and performing ultrasonic treatment until the solution is uniform to obtain a solution A;
(2) adding a certain amount of plant extract and rose essential oil into deionized water, and stirring until the plant extract and the rose essential oil are completely dissolved to obtain a solution B;
(3) adding chitosan into butanediol and ethylhexylglycerin, and uniformly mixing to obtain a solution C;
(4) preparing emulsion by a microfluidic technology, respectively injecting the solution A, B, C into the first flow channel, the second flow channel and the third flow channel, and fully colliding and shearing media in the flow channels at the intersection of the flow channels to obtain the emulsion.
Based on the prepared emulsion, the adding mass concentration of the nano gold is 0.02%, and the adding mass concentration of the hyaluronic acid is 0.8%.
Based on the prepared emulsion, the adding mass concentration of the plant extract is 7%, and the adding mass concentration of the rose essential oil is 2%.
Based on the prepared emulsion, the adding mass concentration of the chitosan is 1%, the adding mass concentration of the butanediol is 9%, and the adding mass concentration of the ethylhexyl glycerin is 5%.
The plant extractive solution is selected from grape seed extract.
The preparation steps of the nano gold sol are as follows:
A. 60mg PVP, 180mg trisodium citrate (Na) are weighed out3C6HSO7) And 30mgNaBr in a 20ml hydrothermal reaction kettle;
B. 0.6g of 20mM NaAuCl was added4Putting the aqueous solution into a hydrothermal reaction kettle, then measuring 8ml of deionized water into the hydrothermal reaction kettle, and magnetically stirring for 15min at room temperature;
C. and C, heating the reaction kettle in the step B to 160 ℃ by a program, reacting for 6 hours at a constant temperature, finishing the reaction, and cooling to room temperature to obtain Au nano (shown in figure 4) sol.
Hydroxyl radical scavenging activity test method: antioxidant activity is expressed in terms of the ability to scavenge hydroxyl radicals. 1. Taking the nano gold colloid of example 1, comparative examples 1 and 2 respectively, centrifuging and washing, and then, obtaining ethanol and deionized water (volume ratio is 1:1)The mixed solution is dispersed to prepare 20mL of gold sol with the same concentration, and then the gold sol is added into 10mL of 2M salicylic acid and 17mL of 2M FeSO which are uniformly mixed in a beaker4Mixing the solution, adding 0.6mL of H with the mass concentration of 0.03%2O2Shaking up and keeping the temperature at 40 ℃ for 25min, and measuring the absorbance Am of the sample group at 510 nm; 2. taking the mixed solution (volume ratio is 1:1) of ethanol and deionized water after centrifugal washing of the nano gold colloids of example 1 and comparative examples 1 and 2 respectively, dispersing and preparing 20mL of gold sol with the same concentration, adding the mixed solution into 10mL of 2M salicylic acid and 17mL of 2M FeSO4 mixed solution which are uniformly mixed in a beaker, then adding 0.6mL of deionized water, shaking uniformly, keeping the temperature at 40 ℃ for 25min, and measuring the absorbance An of a sample group at 510 nm; 3. taking 20mL of mixed solution of ethanol and deionized water (the volume ratio is 1:1), adding 10mL of mixed solution of 2M salicylic acid and 17mL of mixed solution of 2M FeSO4 which are uniformly mixed in a beaker, and then adding 0.6mL of H with the mass concentration of 0.03 percent2O2Shaking and keeping the temperature at 40 ℃ for 25min, and measuring the absorbance A of the sample group at 510nm0. Each of the above three groups was repeated 3 times, and the average value was determined. The clearance was calculated as follows: OH clearance (%) ═ A0-(Am-An)]/A0The x is 100 percent, the clearance rate of the snowflake gold to the hydroxyl free radical in the embodiment 1 is 65.6 percent, the clearance rate of the gold to the hydroxyl free radical in the comparative examples 1 and 2 is 38.4 percent and 31.2 percent, the test result shows that the shapes of the nano-gold are different in oxidation resistance, and the snowflake nano-gold has higher and more effective oxidation resistance effect on the common-shape nano-gold.
Claims (1)
1. A method for preparing cosmetic emulsion containing nanogold comprises the following steps:
(1) preparing a hyaluronic acid aqueous solution, adding the prepared nano gold sol, and performing ultrasonic treatment until the solution is uniform to obtain a solution A;
(2) adding a certain amount of plant extract and rose essential oil into deionized water, and stirring until the plant extract and the rose essential oil are completely dissolved to obtain a solution B;
(3) adding chitosan into butanediol and ethylhexylglycerin, and uniformly mixing to obtain a solution C;
(4) preparing emulsion by a microfluidic technology, respectively injecting the solution A, the solution B and the solution C into the first flow channel, the second flow channel and the third flow channel, and fully colliding and shearing media in the flow channels at the intersection of the flow channels to obtain the emulsion;
the method is characterized in that the plant extract is a grape seed extract, and the preparation steps of the nano gold sol are as follows:
step A, weighing 60mg PVP and 180mg trisodium citrate (Na)3C6HSO7) And 30mgNaBr in a 20ml hydrothermal reaction kettle;
step B, adding 0.6g of 20mM NaAuCl4Putting the aqueous solution into a hydrothermal reaction kettle, then measuring 8ml of deionized water into the hydrothermal reaction kettle, and magnetically stirring for 15min at room temperature;
step C, heating the reaction kettle in the step B to 160 ℃, reacting the reaction liquid for 6 hours at a constant temperature under the magnetic stirring state of 800r/min, finishing the reaction, and cooling to room temperature to obtain snowflake-shaped nanogold sol; based on the prepared emulsion, the adding mass concentration of the nanogold is 0.01-0.05%, the adding mass concentration of the hyaluronic acid is 0.3-1%, the adding mass concentration of the plant extract is 2-8%, the adding mass concentration of the rose essential oil is 1-3%, the adding mass concentration of the chitosan is 0.5-2%, the adding mass concentration of the butanediol is 5-10%, and the adding mass concentration of the ethylhexylglycerin is 5-10%.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202010155197.1A CN111184670B (en) | 2020-03-08 | 2020-03-08 | Cosmetic emulsion containing nanogold component and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202010155197.1A CN111184670B (en) | 2020-03-08 | 2020-03-08 | Cosmetic emulsion containing nanogold component and preparation method thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
CN111184670A CN111184670A (en) | 2020-05-22 |
CN111184670B true CN111184670B (en) | 2022-04-08 |
Family
ID=70702944
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202010155197.1A Active CN111184670B (en) | 2020-03-08 | 2020-03-08 | Cosmetic emulsion containing nanogold component and preparation method thereof |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN111184670B (en) |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20060110600A (en) * | 2005-04-21 | 2006-10-25 | (주)한샘건강 | Pharmaceutical compositions for hair depilation containing silver-nanosolution |
CN102553581A (en) * | 2012-01-13 | 2012-07-11 | 北京化工大学 | Active component morphology controllable loaded noble metal catalyst and preparation method thereof |
CN105127440A (en) * | 2015-07-30 | 2015-12-09 | 哈尔滨工业大学 | Preparing method for gold nanoparticles |
CN107157784A (en) * | 2017-07-06 | 2017-09-15 | 广州诚予化妆品有限公司 | It is a kind of that there is facial mask of reparation antianaphylaxis function and preparation method thereof |
CN110693759A (en) * | 2019-11-19 | 2020-01-17 | 辽宁燕阳医疗设备有限公司 | Anti-aging cosmetic and preparation method thereof |
-
2020
- 2020-03-08 CN CN202010155197.1A patent/CN111184670B/en active Active
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20060110600A (en) * | 2005-04-21 | 2006-10-25 | (주)한샘건강 | Pharmaceutical compositions for hair depilation containing silver-nanosolution |
CN102553581A (en) * | 2012-01-13 | 2012-07-11 | 北京化工大学 | Active component morphology controllable loaded noble metal catalyst and preparation method thereof |
CN105127440A (en) * | 2015-07-30 | 2015-12-09 | 哈尔滨工业大学 | Preparing method for gold nanoparticles |
CN107157784A (en) * | 2017-07-06 | 2017-09-15 | 广州诚予化妆品有限公司 | It is a kind of that there is facial mask of reparation antianaphylaxis function and preparation method thereof |
CN110693759A (en) * | 2019-11-19 | 2020-01-17 | 辽宁燕阳医疗设备有限公司 | Anti-aging cosmetic and preparation method thereof |
Non-Patent Citations (3)
Title |
---|
"纳米金溶胶的制备与应用研究";赫丽娜等;《科技信息》;20091231(第13期);第30-31页 * |
"贵金属纳米材料形貌控制合成的研究进展";张静等;《材料导报A:综述篇》;20130930;第27卷(第9期);第48-53页 * |
Hsin-Chieh Peng等."Quantitative Analysis of the Coverage Density of Br−Ions on Pd{100}".《JACS》.2013,第3780-3783页. * |
Also Published As
Publication number | Publication date |
---|---|
CN111184670A (en) | 2020-05-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP3162762A1 (en) | Porous silica particles, method for producing same, and cosmetic compounded with same | |
EP3632849B1 (en) | Hollow particles and cosmetics containing them | |
CN108785192B (en) | Mineral oil-free natural beauty skin care product and preparation method thereof | |
CN105342867A (en) | Herbal composition submicron lipid carrier and preparation method thereof | |
CN101816302A (en) | Nuclear shell structure intelligent disinfectant containing silver | |
WO2022068173A1 (en) | Retinol inclusion, preparation method therefor and use thereof | |
CN115212123B (en) | Plant extract composition for inhibiting sebum secretion and preparation method and application thereof | |
CN110123674A (en) | A kind of smoothing toner and preparation method thereof containing oil and fat of sacha inchi microcapsules | |
CN111184670B (en) | Cosmetic emulsion containing nanogold component and preparation method thereof | |
CN111514058A (en) | Skin whitening and brightening agent and preparation method thereof | |
CN107287033B (en) | Preparation method of sandalwood essential oil spherical microcapsules | |
KR20150122869A (en) | Cosmetic composition for near infrared ray block and near infrared ray blocker | |
CN106726757B (en) | Peony seed oil microemulsion gel and preparation method thereof | |
CN103690427A (en) | Application of lemon essential oil serving as tyrosinase inhibitor to freckle-removing cosmetics | |
CN112220824A (en) | Antibacterial nano microemulsion system, preparation method, application and application method | |
CN111870574A (en) | Lucid ganoderma compound skin care product and preparation method thereof | |
CN109260031B (en) | Preparation method of combined nutrient liposome for cosmetics | |
CN115282092B (en) | Composition for balancing skin water and oil and application thereof | |
CN115363973B (en) | 4-butylresorcinol co-delivery nano-carrier and preparation method and application thereof | |
CN108283621B (en) | Nasal cavity nano preparation mometasone furoate liquid crystal gel nanoparticle and preparation method thereof | |
CN105560128A (en) | Composition with efficacy of inhibiting sebum secretion and use of composition | |
KR101776140B1 (en) | Cosmetic composition for near infrared ray block and near infrared ray blocker | |
CN110664725B (en) | Preparation method of emulsion containing nanometer propolis extract and emulsion prepared thereby | |
CN117982345B (en) | Colloidal sulfur anti-inflammatory antibacterial agent and preparation method and application thereof | |
JP4890889B2 (en) | Antibacterial cosmetics |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20220317 Address after: 201403 3rd floor, building 11, 6055 Jinhai Road, Fengxian District, Shanghai Applicant after: Shiyin (Shanghai) Biotechnology Co.,Ltd. Address before: No. 060, District 4, Taiben village, Taiping Township, Tuquan County, Xing'an League, Inner Mongolia 137500 Applicant before: Zhang Xueyuan |
|
TA01 | Transfer of patent application right | ||
GR01 | Patent grant | ||
GR01 | Patent grant |