CN111122817A - Pipeline bubble monitoring method and device, storage medium and analysis equipment - Google Patents
Pipeline bubble monitoring method and device, storage medium and analysis equipment Download PDFInfo
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Abstract
The application discloses a pipeline bubble monitoring method, which is applied to analytical equipment for extracting a reagent through a pipeline, and comprises the following steps: acquiring a detection value of a sensor arranged on a pipeline according to the action state of the reagent extracted by the analysis equipment; determining the size of each bubble in the pipeline according to the change of the detection value; determining the gas-liquid mixing ratio in the pipeline according to the change of the detection value; and determining a monitoring result according to the size of the bubbles and the gas-liquid mixing ratio. By applying the technical scheme provided by the embodiment of the application, the monitoring result can be accurately determined, so that whether the bubbles in the pipeline influence the reagent distribution can be conveniently and accurately determined, and the accuracy of the analysis result is improved. The application also discloses a pipeline bubble monitoring device, a storage medium and an analysis device, and the pipeline bubble monitoring device, the storage medium and the analysis device have corresponding technical effects.
Description
Technical Field
The present disclosure relates to the field of detection technologies, and in particular, to a method and an apparatus for monitoring bubbles in a pipeline, a storage medium, and an analysis device.
Background
Currently, in the medical field, there is always a need for analyzing various reagents, which requires analyzing the reagents by using an analyzing apparatus, such as a blood analyzer, a urine analyzer, and the like. When the analyzing apparatus is to analyze the reagent, it is necessary to extract the reagent from the reagent container and distribute the extracted reagent to each component for corresponding analysis.
However, because there are bubbles in the pipeline connecting the analyzing apparatus and the reagent container, or the shaking of the reagent container makes the bubbles melt into the reagent, or the remaining amount of the reagent is insufficient, the bubbles exist in the extracted reagent, and the reagent distribution is affected, for example, the reagent distribution is insufficient, and the analysis result is abnormal.
Therefore, how to monitor the bubbles in the pipeline and determine whether the bubbles in the extracted reagent affect the reagent distribution is a technical problem that needs to be solved urgently by those skilled in the art at present.
Disclosure of Invention
The application aims to provide a pipeline bubble monitoring method, a pipeline bubble monitoring device, a storage medium and an analysis device so as to accurately determine whether bubbles in a pipeline affect reagent distribution.
In order to solve the technical problem, the application provides the following technical scheme:
a method of monitoring pipeline bubbles for use in an analytical apparatus for extracting reagents through a pipeline, the method comprising:
acquiring a detection value of a sensor arranged on the pipeline according to the action state of the analysis equipment for extracting the reagent;
determining the size of each bubble in the pipeline according to the change of the detection value;
determining a gas-liquid mixing ratio in the pipeline according to the change of the detection value;
and determining a monitoring result according to the size of the bubbles and the gas-liquid mixing ratio.
In one embodiment of the present application, when the action state of the analysis device for extracting the reagent is extraction, the detection value is continuously acquired; and when the action state of extracting the reagent by the analysis equipment is extraction stopping, stopping acquiring the detection value.
In one embodiment of the present application, the action state of the analyzing apparatus for extracting the reagent is determined according to the action state of the pump corresponding to the pipeline.
In a specific embodiment of the present application, the determining a size of each bubble in the pipeline according to a change of the detection value includes:
determining the continuous non-conduction time of the sensor according to the change of the detection value;
determining a size of each bubble in the conduit based on the continuous non-conduction time period.
In one embodiment of the present application, the determining a gas-liquid mixture ratio in the pipeline according to a change in the detection value includes:
determining the total non-conduction time of the sensor according to the change of the detection value; determining a gas-liquid mixture ratio based on a ratio of a total non-conduction time period of the sensor to a total time period for acquiring the detection value;
or,
determining the ratio of the non-conduction time length of the sensor in each unit time according to the change of the detection value; the gas-liquid mixture ratio is determined based on the ratio of the non-conduction period to the non-conduction period in each unit time.
In one embodiment of the present application, the determining the monitoring result according to the size of the bubble and the gas-liquid mixing ratio includes:
if the size of a single bubble is larger than a set first threshold value and the gas-liquid mixing ratio is larger than a set second threshold value, determining that the bubble in the pipeline influences the reagent distribution.
In one embodiment of the present application, the method further includes:
and if it is determined that the bubbles in the pipeline influence reagent distribution, outputting alarm information.
A pipeline bubble monitoring device for use with analytical equipment for extracting reagents through a pipeline, the device comprising:
the detection value acquisition module is used for acquiring the detection value of a sensor arranged on the pipeline according to the action state of the reagent extracted by the analysis equipment;
the bubble size determining module is used for determining the size of each bubble in the pipeline according to the change of the detection value;
the gas-liquid mixing ratio determining module is used for determining the gas-liquid mixing ratio in the pipeline according to the change of the detection value;
and the monitoring result determining module is used for determining a monitoring result according to the size of the bubbles and the gas-liquid mixing ratio.
An analysis apparatus comprising:
a pump for pumping the reagent;
a conduit connected to the pump through the reagent;
a sensor disposed on the conduit;
a memory for storing a computer program;
and the processor is in communication connection with the pump and the sensor and is used for realizing the steps of the pipeline bubble monitoring method when the computer program is executed.
A computer readable storage medium having a computer program stored thereon, which when executed by a processor implements the steps of the pipeline bubble monitoring method of any of the above.
By applying the technical scheme provided by the embodiment of the application, the sensor is arranged on the pipeline, the detection value of the sensor is obtained according to the action state of the reagent extracted by the analysis equipment, the size of each bubble in the pipeline and the gas-liquid mixing ratio are determined according to the change of the detection value, the monitoring result is accurately determined according to the size of each bubble and the gas-liquid mixing ratio, so that whether the bubble in the pipeline influences the reagent distribution or not is conveniently and accurately determined, and the accuracy of the analysis result is improved.
Drawings
In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present application, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.
FIG. 1 is a schematic structural diagram of a pipeline bubble monitoring system according to an embodiment of the present disclosure;
FIG. 2 is a schematic structural diagram of a method for monitoring pipeline bubbles in an embodiment of the present application;
FIG. 3 is a schematic structural diagram of a pipeline bubble monitoring device according to an embodiment of the present disclosure;
FIG. 4 is a schematic structural diagram of an analysis apparatus in an embodiment of the present application;
Detailed Description
The core of the application is to provide a pipeline bubble monitoring method, which can be applied to analytical equipment for extracting reagents through pipelines.
As shown in fig. 1, the analytical device is in communication with the reagent container, and a sensor is provided on a conduit in communication with the analytical device, and the analytical device is connected to the sensor. According to the action state of the analysis equipment for extracting the reagent, the detection value of a sensor arranged on the pipeline can be obtained, the size of each bubble in the pipeline and the gas-liquid mixing ratio in the pipeline can be determined according to the change of the detection value, the monitoring result can be accurately determined according to the size of the bubble and the gas-liquid mixing ratio, and then whether the bubble in the pipeline influences the reagent distribution or not can be determined according to the monitoring result.
The processor in the analysis device may be specifically an FPGA (Field Programmable Gate Array), has a good real-time processing capability, and may also be other processors such as a Central Processing Unit (CPU).
The sensor may be one of a photoelectric sensor, an electromagnetic sensor, an ultrasonic sensor, and the like.
In order that those skilled in the art will better understand the disclosure, the following detailed description will be given with reference to the accompanying drawings. It is to be understood that the embodiments described are only a few embodiments of the present application and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.
Referring to fig. 2, there is shown a flowchart for implementing a method for monitoring pipeline bubbles according to an embodiment of the present application, where the method may include the following steps:
s210: and acquiring the detection value of a sensor arranged on the pipeline according to the action state of the reagent extracted by the analysis equipment.
In this application embodiment, analytical equipment and reagent container UNICOM are provided with the sensor in the pipeline of UNICOM, and analytical equipment is connected with the sensor, and when analytical equipment extracted reagent from the reagent container, the reagent flow of extraction through the sensor that sets up in the pipeline, the sensor can detect it, and analytical equipment can acquire the measuring value of sensor. The detection value of the sensor may be whether or not to be on, the on-time period, or the like.
Taking the sensor as an example, the photosensor emits infrared emission light, if the liquid passing through the sensor is uniform and transparent, the infrared emission light is refracted by the liquid, and then the receiver can receive enough light, in which case the photosensor is in a conducting state, if the liquid passing through the sensor is a bubble, the infrared emission light is scattered, and the receiver cannot receive enough light, in which case the photosensor is in a non-conducting state.
In the embodiment of the present application, when the operation state of the analyzing apparatus for extracting the reagent is extraction, the detection value is continuously acquired, and when the operation state of the analyzing apparatus for extracting the reagent is extraction stop, the detection value is stopped. That is, during the process of extracting a reagent by the analyzing apparatus, the extracted reagent flows through the sensor in the piping, and the sensor detects it, and a detection value can be obtained, during which the analyzing apparatus can continuously acquire the detection value. The acquisition of the detection value may be stopped if the analysis device stops extracting reagent.
The action state of the analysis device for extracting the reagent can be determined according to the action state of the pump corresponding to the pipeline. And if the pump corresponding to the pipeline is in the sucking state, the action state of the analysis equipment for sucking the reagent is in the sucking state, and if the pump corresponding to the pipeline is in the sucking stopping state, the action state of the analysis equipment for sucking the reagent is in the sucking stopping state.
S220: and determining the size of each bubble in the pipeline according to the change of the detection value.
The sensor detects the reagent flowing through the pipeline, and can obtain detection values such as whether the reagent is conducted, the conduction time length and the non-conduction time length. If there are bubbles in the reagent being withdrawn, the sensor will be in a non-conducting state when the bubbles pass the sensor and in a conducting state when the liquid passes the sensor.
In the embodiment of the present application, the size of each bubble in the pipeline may be determined according to the change of the detection value. For example, the continuous non-conducting time of the sensor is determined according to the change of the detection value, and the continuous non-conducting time of the sensor is used for representing the size of the bubble. The larger the continuous non-conduction period is, the larger the bubble is, and the smaller the continuous non-conduction period is, the smaller the bubble is.
According to the change of the detection value of the sensor, the size of each bubble in the pipeline can be accurately determined.
S230: and determining the gas-liquid mixing ratio in the pipeline according to the change of the detection value.
The sensor detects the reagent flowing through the pipeline, and can obtain detection values such as whether the reagent is conducted, the conduction time length and the non-conduction time length. If there are bubbles in the reagent being withdrawn, the sensor will be in a non-conducting state when the bubbles pass the sensor and in a conducting state when the liquid passes the sensor.
In the embodiment of the present application, the gas-liquid mixture ratio in the pipe may be determined based on a change in the detected value. If the total non-conduction time of the sensor can be determined according to the change of the detection value, the ratio of the total non-conduction time of the sensor to the total time for obtaining the detection value can be used for representing the proportion of bubbles in the extracted reagent.
According to the change of the detection value of the sensor, the gas-liquid mixing ratio in the pipeline can be accurately determined.
S240: and determining a monitoring result according to the size of the bubbles and the gas-liquid mixing ratio.
In the embodiment of the present application, during the extraction of the reagent from the reagent container by the analyzing apparatus through the pipeline, the detection value of the sensor is acquired according to the action state of the analyzing apparatus for extracting the reagent, and the size of each bubble in the pipeline and the gas-liquid mixing ratio can be determined according to the change of the detection value. Both the size of the bubbles and the gas-liquid mixing ratio are factors that influence reagent dispensing. The larger the single bubble is, the larger the influence is, and the larger the gas-liquid mixture ratio is, the larger the influence is.
The influence condition may be preset according to actual conditions, and after determining the size of the bubble and the gas-liquid mixing ratio, it may be further determined whether the size of the bubble and the gas-liquid mixing ratio reach the influence condition, thereby determining whether the bubble in the pipeline influences the reagent dispensing.
In practical application, in the process that the analysis equipment extracts the reagent from the reagent container, after the detection value of the sensor is obtained, the size of each bubble and the gas-liquid mixing ratio in the current pipeline can be determined in real time, whether the bubble in the pipeline influences reagent distribution or not is determined according to the size of the bubble and the gas-liquid mixing ratio, and as long as the bubble in the pipeline influences the reagent distribution is determined, the pump corresponding to the pipeline can be controlled to stop reagent suction, so that reagent replacement or abnormal condition treatment can be performed in time. Of course, it is also possible to determine the size of each bubble in the pipeline and the gas-liquid mixing ratio according to the change of the detection value of the sensor after the reagent extraction is finished, and determine whether the bubble in the pipeline affects the reagent distribution based on the size.
By applying the method provided by the embodiment of the application, the sensor is arranged on the pipeline, the detection value of the sensor is obtained according to the action state of the reagent extracted by the analysis equipment, the size of each bubble in the pipeline and the gas-liquid mixing ratio are determined according to the change of the detection value, the monitoring result is accurately determined according to the size of the bubble and the gas-liquid mixing ratio, whether the bubble in the pipeline influences the reagent distribution or not is conveniently and accurately determined, and the accuracy of the analysis result is improved.
Whether the bubbles in the pipeline influence reagent distribution is accurately judged based on the two parameters of the size of the bubbles and the gas-liquid mixing ratio, and compared with a scheme of alarming as long as the bubbles in the pipeline are detected, the method can avoid misinformation to a greater extent. Meanwhile, the flowing reagent is detected through the sensor, the requirement on the sensor is low, and the hardware cost can be saved.
In one embodiment of the present application, step S220 may include the steps of:
the method comprises the following steps: determining the continuous non-conduction time of the sensor according to the change of the detection value;
step two: the size of each bubble in the pipeline is determined based on the continuous non-conduction time.
For ease of understanding, the above two steps are described in combination.
The detection value of the sensor can be whether the sensor is conducted or not, the conduction time length, the non-conduction time length and the like, the continuous non-conduction time length of the sensor can be determined according to the change of the detection value of the sensor, and the continuous non-conduction time length can be multiple. If in the reagent extraction process, 0ms-10ms is not conducted, 30ms-50ms is not conducted, 100ms-130ms is not conducted, and the continuous non-conduction time is 3, namely 10ms, 20ms and 30 ms.
The length of the continuous non-conduction time is positively correlated with the size of the bubbles, the longer the continuous non-conduction time is, the larger the bubbles are, the shorter the continuous non-conduction time is, and the smaller the bubbles are. The correspondence between the continuous non-conduction time length and the size of the bubble can be predetermined according to historical data. If the bubble size is f (continuous non-conducting time), f () is a relational function. Based on the duration of the continuous non-conduction, the size of each bubble in the pipeline may be determined.
Through the continuous non-conduction time, the size of each bubble in the pipeline can be accurately determined, so that subsequent further judgment can be facilitated.
In one embodiment of the present application, step S230 may include the steps of:
the method comprises the following steps: determining the total non-conduction time of the sensor according to the change of the detection value;
step two: the gas-liquid mixture ratio is determined based on a ratio of a total non-conduction time period of the sensor to a total time period of the acquired detection value.
For convenience of description, the above two steps are combined for illustration.
In the embodiment of the present application, the detection value of the sensor may be whether to be turned on, a turn-on duration, a turn-off duration, or the like. The total non-conducting time of the sensor may be determined according to a change in a detection value of the sensor, and the total non-conducting time may be an accumulated result of a plurality of consecutive non-conducting times. If in the reagent extraction process, 0ms-10ms is not conducted, 30ms-50ms is not conducted, 100ms-130ms is not conducted, the continuous non-conduction time is 3, namely 10ms, 20ms and 30ms, and the total non-conduction time is 60 ms.
Further, the ratio of the total non-conduction time length to the total time length for acquiring the detection value can be calculated, and the size of the ratio can represent the proportion of bubbles in the currently extracted reagent. Based on the ratio, the gas-liquid mixture ratio can be determined. Specifically, the gas-liquid mixture ratio may be equal to a ratio of the total non-conduction period of the sensor to the total period of time for which the detection value is acquired, or equal to the ratio multiplied by a set weight. The setting weight can be set and adjusted according to actual conditions.
For example, if the total non-conduction period of the sensors is 60ms and the total period of the currently acquired detection values is 150ms, the determined gas-liquid mixture ratio may be equal to 60/150-2/5.
Based on the ratio of the total non-conduction time length to the total time length of the acquired detection value, the gas-liquid mixing ratio can be accurately determined, so that the subsequent further judgment can be facilitated.
In an embodiment of the present application, step S230 may further include the steps of:
the method comprises the following steps: determining the ratio of the non-conduction time length of the sensor in each unit time according to the change of the detection value;
step two: the gas-liquid mixture ratio is determined based on the ratio of the non-conduction period to the non-conduction period in each unit time.
For convenience of description, the above two steps are combined for illustration.
In the embodiment of the present application, a unit time, such as 50ms, may be set. After the detection value of the sensor is acquired in the process of extracting the reagent, the ratio of the non-conduction time length of the sensor in each unit time can be determined according to the change of the detection value of the sensor. Specifically, the ratio of the non-conducting time duration in the unit time may be equal to the ratio of the total non-conducting time duration in the unit time to the unit time duration. If the total non-conducting time period in the first 50ms is 10ms, the non-conducting time period ratio in the unit time is 1/5, and the total non-conducting time period in the second 50ms is 30ms, the non-conducting time period ratio in the unit time is 3/5.
The gas-liquid mixture ratio may be determined based on the ratio of the non-conduction period to the time period per unit time. If the gas-liquid mixing ratio in the first unit time 50ms is 1/5, the gas-liquid mixing ratio in the second unit time 50ms is 3/5.
When judging the influence of the size of the bubbles and the gas-liquid mixing ratio on reagent distribution, the bubbles in the pipeline can be determined to influence the reagent distribution as long as the size of a single bubble and the gas-liquid mixing ratio in a single unit time meet the influence condition.
In one embodiment of the present application, step S240 may include the steps of:
if the size of a single bubble is larger than a set first threshold value and the gas-liquid mixing ratio is larger than a set second threshold value, determining that the bubble in the pipeline influences the reagent distribution.
In the embodiment of the application, after the size of each bubble and the gas-liquid mixing ratio in the pipeline are determined according to the change of the detection value of the sensor during the reagent extraction process, the size of each bubble can be compared with a set first threshold value, the gas-liquid mixing ratio can be compared with a set second threshold value, and if the size of a single bubble is larger than the set first threshold value and the gas-liquid mixing ratio is larger than the set second threshold value, the bubble in the pipeline can be determined to influence the reagent distribution.
The size of each bubble can be compared with a set first threshold value in real time, the gas-liquid mixing ratio can be compared with a set second threshold value, and as long as the size of a single bubble is larger than the set first threshold value and the gas-liquid mixing ratio is larger than the set second threshold value, the bubble in the pipeline can be determined to influence reagent distribution, so that reagent can not be extracted any more, and abnormal conditions can be timely treated. Of course, after the reagent extraction is finished, the size of each bubble can be compared with a set first threshold value, the gas-liquid mixing ratio can be compared with a set second threshold value, when the size of a single bubble is larger than the set first threshold value and the gas-liquid mixing ratio is larger than the set second threshold value, the bubble in the pipeline is determined to influence the reagent distribution, the extracted reagent is not distributed, and the accuracy of the analysis result is prevented from being influenced.
The first threshold and the second threshold can be set and adjusted according to actual conditions, such as flexible setting according to reagent types, pipeline sizes, extraction speeds and the like. In practical application, a threshold list may be generated by obtaining a first threshold and a second threshold corresponding to a reagent type, a pipeline size, an extraction speed, and the like through analysis of historical data in advance, and the threshold list may be searched for when reagent distribution influence needs to be determined.
In one embodiment of the present application, the method may further comprise the steps of:
and if the bubbles in the pipeline are determined to influence reagent distribution, outputting alarm information.
In the embodiment of the application, in the process of extracting the reagent, the size of each bubble in the pipeline and the gas-liquid mixing ratio are determined according to the change of the detection value of the sensor, and according to the size of the bubble and the gas-liquid mixing ratio, if the bubble in the pipeline is determined to influence the reagent distribution, alarm information can be output to prompt that the bubble in the pipeline will influence the reagent distribution, so that abnormal conditions can be timely processed. The output of the alarm information can be performed in a sound mode, a light mode, a short message reminding mode and the like.
In one embodiment of the present application, the method may further comprise the steps of:
and if the reagent extraction is finished and the bubbles in the pipeline are determined not to influence the reagent distribution, distributing the extracted reagent to each component of the analysis equipment according to a preset rule.
In the embodiment of the application, during the reagent extraction process, the size of each air bubble in the pipeline and the gas-liquid mixing ratio are determined according to the change of the detection value of the sensor, and according to the size of the air bubble and the size of the gas-liquid mixing ratio, if the air bubble in the pipeline is determined not to influence the reagent distribution and the reagent extraction is finished, the extracted reagent can be distributed to each component of the analysis equipment, such as a counting component, a measuring component and the like, according to a set rule, so that each component can correspondingly process and analyze the distributed reagent. Under the condition that the bubbles in the pipeline are determined not to influence the distribution of the reagent, the extracted reagent is distributed to each component, so that the accuracy of the analysis result of each component can be improved.
It should be noted that, in the embodiment of the present application, when the processor is an FPGA, based on parallelism and expandability of the FPGA, multiple paths of reagents may be extracted simultaneously, and the multiple paths of reagents may be detected respectively.
Corresponding to the above method embodiment, the present application further provides a pipeline bubble monitoring device, which is applied to an analysis apparatus for extracting a reagent through a pipeline, and the pipeline bubble monitoring device described below and the pipeline bubble monitoring method described above may be referred to in correspondence.
Referring to fig. 3, the apparatus may include the following modules:
a detection value acquisition module 310, configured to acquire a detection value of a sensor provided on a pipeline according to an action state of reagent extraction by an analysis device;
the bubble size determining module 320 is configured to determine the size of each bubble in the pipeline according to a change in the detection value;
a gas-liquid mixing ratio determining module 330 for determining a gas-liquid mixing ratio in the pipeline according to a change in the detection value;
and a monitoring result determining module 340 for determining a monitoring result according to the size of the bubble and the gas-liquid mixing ratio.
By applying the device provided by the embodiment of the application, the sensor is arranged on the pipeline, the detection value of the sensor is obtained according to the action state of the reagent extracted by the analysis equipment, the size of each bubble in the pipeline and the gas-liquid mixing ratio are determined according to the change of the detection value, the monitoring result is accurately determined according to the size of the bubble and the gas-liquid mixing ratio, whether the bubble in the pipeline influences the reagent distribution or not is conveniently and accurately determined, and the accuracy of the analysis result is improved.
In a specific embodiment of the present application, the apparatus further includes a control module, configured to:
when the action state of the analysis equipment for extracting the reagent is extracting, continuously acquiring a detection value; when the action state of the analysis equipment for extracting the reagent is extraction stopping, the acquisition of the detection value is stopped.
In one embodiment of the present application, the control module is further configured to:
and determining the action state of the analysis equipment for extracting the reagent according to the action state of the pump corresponding to the pipeline.
In one embodiment of the present application, the bubble size determining module 320 is configured to:
determining the continuous non-conduction time of the sensor according to the change of the detection value;
the size of each bubble in the pipeline is determined based on the continuous non-conduction time.
In one embodiment of the present application, the gas-liquid mixture ratio determination module 330 is configured to:
determining the total non-conduction time of the sensor according to the change of the detection value; determining a gas-liquid mixing ratio based on a ratio of the total non-conduction time length of the sensor to the total time length of the acquired detection value;
or,
determining the ratio of the non-conduction time length of the sensor in each unit time according to the change of the detection value; the gas-liquid mixture ratio is determined based on the ratio of the non-conduction period to the non-conduction period in each unit time.
In one embodiment of the present application, the monitoring result determining module 340 is configured to:
if the size of a single bubble is larger than a set first threshold value and the gas-liquid mixing ratio is larger than a set second threshold value, determining that the bubble in the pipeline influences the reagent distribution.
In a specific embodiment of the present application, the system further includes an alarm module, configured to:
and if the bubbles in the pipeline are determined to influence reagent distribution, outputting alarm information.
Corresponding to the above method embodiment, an embodiment of the present application further provides an analysis apparatus, including:
a pump for pumping the reagent;
a line connected to the pump through which the reagent passes;
a sensor disposed on the pipeline;
a memory for storing a computer program;
and the processor is in communication connection with the pump and the sensor and is used for realizing the steps of the pipeline bubble monitoring method when executing a computer program.
As shown in fig. 4, in order to illustrate the structure of the analysis device, the analysis device may include: processor 10, memory 11, communication interface 12 and communication bus 13, and also includes pump 14, sensors 15 disposed on the lines. The processor 10, the memory 11, the communication interface 12, the pump 14 and the sensor 15 are all communicated with each other through a communication bus 13.
In the embodiment of the present application, the processor 10 may be a Central Processing Unit (CPU), an application specific integrated circuit, a digital signal processor, a field programmable gate array or other programmable logic device, etc.
The processor 10 may call a program stored in the memory 11, and in particular, the processor 10 may perform operations in an embodiment of the line bubble monitoring method.
The memory 11 is used for storing one or more programs, the program may include program codes, the program codes include computer operation instructions, in this embodiment, the memory 11 stores at least the program for implementing the following functions:
acquiring a detection value of a sensor arranged on a pipeline according to the action state of the reagent extracted by the analysis equipment;
determining the size of each bubble in the pipeline according to the change of the detection value;
determining the gas-liquid mixing ratio in the pipeline according to the change of the detection value;
and determining a monitoring result according to the size of the bubbles and the gas-liquid mixing ratio.
In one possible implementation, the memory 11 may include a program storage area and a data storage area, wherein the program storage area may store an operating system, an application program required for at least one function (such as a sound playing function and an image playing function), and the like; the storage data area may store data created during use, such as detection data, calculation data, and the like.
Further, the memory 11 may include high speed random access memory, and may also include non-volatile memory, such as at least one magnetic disk storage device or other volatile solid state storage device.
The communication interface 13 may be an interface of a communication module for connecting with other devices or systems.
Of course, it should be noted that the structure shown in fig. 4 does not constitute a limitation to the analysis device in the embodiment of the present application, and in practical applications, the analysis device may include more or less components than those shown in fig. 4, or some components may be combined, such as the analysis device further includes a counting assembly, a measuring assembly, and the like.
Corresponding to the above method embodiment, this application embodiment further provides a computer readable storage medium, on which a computer program is stored, and when the computer program is executed by a processor, the steps of the pipeline bubble monitoring method are implemented.
The embodiments are described in a progressive manner, each embodiment focuses on differences from other embodiments, and the same or similar parts among the embodiments are referred to each other.
Those of skill would further appreciate that the various illustrative elements and algorithm steps described in connection with the embodiments disclosed herein may be implemented as electronic hardware, computer software, or combinations of both, and that the various illustrative components and steps have been described above generally in terms of their functionality in order to clearly illustrate this interchangeability of hardware and software. Whether such functionality is implemented as hardware or software depends upon the particular application and design constraints imposed on the implementation. Skilled artisans may implement the described functionality in varying ways for each particular application, but such implementation decisions should not be interpreted as causing a departure from the scope of the present application.
The steps of a method or algorithm described in connection with the embodiments disclosed herein may be embodied directly in hardware, in a software module executed by a processor, or in a combination of the two. A software module may reside in Random Access Memory (RAM), memory, Read Only Memory (ROM), electrically programmable ROM, electrically erasable programmable ROM, registers, hard disk, a removable disk, a CD-ROM, or any other form of storage medium known in the art.
The principle and the implementation of the present application are explained in the present application by using specific examples, and the above description of the embodiments is only used to help understanding the technical solution and the core idea of the present application. It should be noted that, for those skilled in the art, it is possible to make several improvements and modifications to the present application without departing from the principle of the present application, and such improvements and modifications also fall within the scope of the claims of the present application.
Claims (10)
1. A method of monitoring bubbles in a pipeline, for use in an analytical apparatus for extracting a reagent through a pipeline, the method comprising:
acquiring a detection value of a sensor arranged on the pipeline according to the action state of the analysis equipment for extracting the reagent;
determining the size of each bubble in the pipeline according to the change of the detection value;
determining a gas-liquid mixing ratio in the pipeline according to the change of the detection value;
and determining a monitoring result according to the size of the bubbles and the gas-liquid mixing ratio.
2. The method according to claim 1, wherein the detection value is continuously acquired when the action state of the analysis device for extracting the reagent is extraction; and when the action state of extracting the reagent by the analysis equipment is extraction stopping, stopping acquiring the detection value.
3. The method according to claim 2, wherein the action state of the analytical device for extracting the reagent is determined according to the action state of the pump corresponding to the pipeline.
4. The method of claim 1, wherein determining the size of each bubble in the conduit based on the change in the detected value comprises:
determining the continuous non-conduction time of the sensor according to the change of the detection value;
determining a size of each bubble in the conduit based on the continuous non-conduction time period.
5. The method of claim 1, wherein determining the gas-to-liquid mixture ratio in the pipeline based on the change in the detected value comprises:
determining the total non-conduction time of the sensor according to the change of the detection value; determining a gas-liquid mixture ratio based on a ratio of a total non-conduction time period of the sensor to a total time period for acquiring the detection value;
or,
determining the ratio of the non-conduction time length of the sensor in each unit time according to the change of the detection value; the gas-liquid mixture ratio is determined based on the ratio of the non-conduction period to the non-conduction period in each unit time.
6. The method according to any one of claims 1 to 5, wherein the determining a monitoring result according to the size of the bubbles and the gas-liquid mixing ratio includes:
if the size of a single bubble is larger than a set first threshold value and the gas-liquid mixing ratio is larger than a set second threshold value, determining that the bubble in the pipeline influences the reagent distribution.
7. The method of claim 6, further comprising:
and if it is determined that the bubbles in the pipeline influence reagent distribution, outputting alarm information.
8. A pipeline bubble monitoring device for use with analytical equipment for extracting reagents through a pipeline, the device comprising:
the detection value acquisition module is used for acquiring the detection value of a sensor arranged on the pipeline according to the action state of the reagent extracted by the analysis equipment;
the bubble size determining module is used for determining the size of each bubble in the pipeline according to the change of the detection value;
the gas-liquid mixing ratio determining module is used for determining the gas-liquid mixing ratio in the pipeline according to the change of the detection value;
and the monitoring result determining module is used for determining a monitoring result according to the size of the bubbles and the gas-liquid mixing ratio.
9. An analysis apparatus, comprising:
a pump for pumping the reagent;
a conduit connected to the pump through the reagent;
a sensor disposed on the conduit;
a memory for storing a computer program;
a processor, communicatively connected to the pump and the sensor, for implementing the steps of the pipeline bubble monitoring method according to any one of claims 1 to 7 when executing the computer program.
10. A computer-readable storage medium, having stored thereon a computer program which, when being executed by a processor, carries out the steps of the method for pipeline bubble monitoring according to any one of claims 1 to 7.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112305242A (en) * | 2020-10-28 | 2021-02-02 | 广东恒度检测科技有限公司 | Biochemical automatic checkout device |
| CN113908383A (en) * | 2021-12-14 | 2022-01-11 | 极限人工智能有限公司 | Bubble detection method and device and triple tee system |
| CN114993580A (en) * | 2022-08-01 | 2022-09-02 | 深圳赛桥生物创新技术有限公司 | Consumable installation detection method, device and system and storage medium |
| CN115575187A (en) * | 2022-10-08 | 2023-01-06 | 马鞍山市桓泰环保设备有限公司 | Feed liquor compensation control system of water quality analyzer |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1472185A (en) * | 1973-05-22 | 1977-05-04 | Hectronic Ag | Liquid detectors |
| WO2007119662A1 (en) * | 2006-04-06 | 2007-10-25 | Olympus Corporation | Method of determining whether there are air bubbles in piping of dispensing device, and dispensing device |
| CN106501215A (en) * | 2016-10-31 | 2017-03-15 | 天津科技大学 | A kind of microbubble volumetric concentration measurement apparatus |
| US20180075299A1 (en) * | 2016-09-09 | 2018-03-15 | Medtronic, Inc. | Gas bubble detector |
| CN109030093A (en) * | 2017-06-08 | 2018-12-18 | 深圳迈瑞生物医疗电子股份有限公司 | Bubble monitoring method, bubble monitoring device and sample analyser |
-
2019
- 2019-12-30 CN CN201911398096.0A patent/CN111122817A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1472185A (en) * | 1973-05-22 | 1977-05-04 | Hectronic Ag | Liquid detectors |
| WO2007119662A1 (en) * | 2006-04-06 | 2007-10-25 | Olympus Corporation | Method of determining whether there are air bubbles in piping of dispensing device, and dispensing device |
| US20180075299A1 (en) * | 2016-09-09 | 2018-03-15 | Medtronic, Inc. | Gas bubble detector |
| CN106501215A (en) * | 2016-10-31 | 2017-03-15 | 天津科技大学 | A kind of microbubble volumetric concentration measurement apparatus |
| CN109030093A (en) * | 2017-06-08 | 2018-12-18 | 深圳迈瑞生物医疗电子股份有限公司 | Bubble monitoring method, bubble monitoring device and sample analyser |
Non-Patent Citations (1)
| Title |
|---|
| 蔡莉等: "输液泵气泡检测方法研究", 《中国医学装备》 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112305242A (en) * | 2020-10-28 | 2021-02-02 | 广东恒度检测科技有限公司 | Biochemical automatic checkout device |
| CN113908383A (en) * | 2021-12-14 | 2022-01-11 | 极限人工智能有限公司 | Bubble detection method and device and triple tee system |
| CN114993580A (en) * | 2022-08-01 | 2022-09-02 | 深圳赛桥生物创新技术有限公司 | Consumable installation detection method, device and system and storage medium |
| CN115575187A (en) * | 2022-10-08 | 2023-01-06 | 马鞍山市桓泰环保设备有限公司 | Feed liquor compensation control system of water quality analyzer |
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