CN111110769A - Preparation method of analgesic moxibustion - Google Patents

Preparation method of analgesic moxibustion Download PDF

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Publication number
CN111110769A
CN111110769A CN202010068088.6A CN202010068088A CN111110769A CN 111110769 A CN111110769 A CN 111110769A CN 202010068088 A CN202010068088 A CN 202010068088A CN 111110769 A CN111110769 A CN 111110769A
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parts
moxibustion
analgesic
chitosan
auxiliary agent
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刘成
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Hangzhou gongyanlou Culture Development Co.,Ltd.
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Mituo Mida Health Management Co ltd
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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    • AHUMAN NECESSITIES
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    • A61HPHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H39/00Devices for locating or stimulating specific reflex points of the body for physical therapy, e.g. acupuncture
    • A61H39/06Devices for heating or cooling such points within cell-life limits
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Abstract

The application discloses a preparation method of analgesic moxibustion, which comprises the following steps: s1, cutting folium artemisiae argyi, agastache rugosus, semen brassicae, safflower, cinnamon, rhizoma atractylodis, mangnolia officinalis, agilawood and radix dipsaci, uniformly mixing, adding water, mixing, heating to 80-120 ℃, cooking for 20-40min, and then evaporating and concentrating to obtain a material a; s2, uniformly mixing the material a, the pinellia ternate, the monkshood, the rhizoma typhonii, the rheum officinale, the chitosan and the slow-release auxiliary agent, heating to 80-90 ℃, centrifuging at the rotating speed of 1500-; s3, concentrating the centrifugal glue solution in the S2, and then preparing the analgesic moxibustion with a strip-shaped structure in a rod making machine. The analgesic moxibustion prepared by the invention has excellent absorption efficiency of the effective components of the medicine.

Description

Preparation method of analgesic moxibustion
[ technical field ] A method for producing a semiconductor device
The invention relates to the field of health care products, in particular to a preparation method of analgesic moxibustion.
[ background of the invention ]
Moxibustion is a moxibustion method in traditional Chinese medicine acupuncture therapy. Moxa cones and moxa sticks made of mugwort leaves are mainly ignited to smoke and bake acupuncture points of a human body so as to achieve a natural therapy for health care and disease treatment. In ancient China, wormwood has been an important civilian plant. Is commonly used in "moxibustion" for acupuncture. So-called acupuncture is actually divided into two parts. The acupuncture points are pricked by taking the needle, while the moxibustion points are smoked and scalded after the moxa is ignited, and the points are stimulated by heat, but the moxibustion points can be used when any paper or grass is ignited. The smell of the wormwood certainly plays a certain role at the same time. When Chinese folk uses the cupping jar method to treat rheumatism, the effect is better when the wormwood is used as fuel.
Chinese patent application document 'moxibustion paste and preparation method and application thereof (application number: 201610708042. X)' discloses moxibustion paste and preparation method and application thereof. The moxibustion ointment is mainly prepared from the following raw materials in parts by weight: 80-120 parts of folium artemisiae argyi and 2-5.5 parts of moxa. However, the absorption efficiency of the drug effect cannot meet the requirement in practical use.
[ summary of the invention ]
The invention provides a preparation method of analgesic moxibustion, aiming at solving the problem of how to optimize components, dosage and the like on the basis of the analgesic moxibustion disclosed in Chinese patent application document 'Chinese medicinal moxibustion formula (application number: 201310063316.0)', and improving the drug absorption efficiency of the analgesic moxibustion.
In order to solve the technical problems, the invention adopts the following technical scheme:
a preparation method of analgesic moxibustion comprises the following steps:
s1, cutting folium artemisiae argyi, agastache rugosus, semen brassicae, safflower, cinnamon, rhizoma atractylodis, mangnolia officinalis, agilawood and radix dipsaci, uniformly mixing, adding water, mixing, heating to 80-120 ℃, cooking for 20-40min, and then evaporating and concentrating to obtain a material a;
s2, uniformly mixing the material a, the pinellia ternate, the monkshood, the rhizoma typhonii, the rheum officinale, the chitosan and the slow-release auxiliary agent, heating to 80-90 ℃, centrifuging at the rotating speed of 1500-;
s3, concentrating the centrifugal glue solution in the S2, and then preparing the analgesic moxibustion with a strip-shaped structure in a rod making machine.
In the invention, the analgesic moxibustion comprises the following raw materials: folium artemisiae argyi, agastache rugosus, semen brassicae, safflower, cinnamon, rhizoma atractylodis, mangnolia officinalis, agilawood, radix dipsaci, pinellia ternate, radix aconiti, rhizoma typhonii, rheum officinale, chitosan and a slow-release auxiliary agent.
In the invention, the slow release auxiliary agent comprises the following raw materials: rice hull powder, chitosan, donkey-hide gelatin, tapioca, seaweed and soybean lecithin.
In the invention, the weight ratio of the pinellia ternate to the monkshood, the rhizoma typhonii to the rheum officinale to the chitosan to the slow-release auxiliary agent is (5-15) to (4-8) to (3-6) to (8-16) to (6-9) to (15-20).
In the embodiment of the invention, the weight ratio of the pinellia ternate to the monkshood, the rhizoma typhonii to the rheum officinale to the chitosan to the slow-release auxiliary agent is 10.5:5.8:4.7:13.2:7.4: 18.6.
In the invention, the analgesic moxibustion comprises the following raw materials in parts by weight: 40-90 parts of folium artemisiae argyi, 40-60 parts of wrinkled gianthyssop herb, 15-25 parts of semen brassicae, 4-8 parts of safflower, 2-8 parts of cinnamon, 1-8 parts of rhizoma atractylodis, 4-8 parts of mangnolia officinalis, 3-6 parts of agilawood, 2-5 parts of radix dipsaci, 5-15 parts of pinellia ternate, 4-8 parts of radix aconiti, 3-6 parts of rhizoma typhonii, 8-16 parts of rheum officinale, 6-9 parts of chitosan and 15-20 parts of slow-release auxiliary agent.
In the invention, the slow release auxiliary comprises the following raw materials in parts by weight: 40-50 parts of rice hull powder, 15-25 parts of chitosan, 8-16 parts of donkey-hide gelatin, 4-8 parts of cassava powder, 3-9 parts of seaweed and 8-16 parts of soybean lecithin.
In the invention, the slow release auxiliary agent is prepared by the following process: uniformly mixing rice hull powder, chitosan and distilled water, uniformly stirring at the speed of 850-1050r/min, then adding donkey-hide gelatin, cassava powder, seaweed and soybean lecithin, stirring for 4-6h at the speed of 280-320r/min in a constant-temperature water bath at the temperature of 65-75 ℃, then cooling to room temperature, carrying out suction filtration to obtain a precipitate, drying the precipitate at the temperature of 45-55 ℃ for 44-52h, and cooling to room temperature to obtain the slow-release auxiliary agent.
The invention has the following beneficial effects:
(1) as can be seen from the data of examples 1-3 and comparative example 8, the absorption efficiency of the analgesic moxibustion of examples 1-3 of the present invention is significantly higher than that of the prior art; meanwhile, as can be seen from the data of examples 1 to 3, example 1 is the most preferred example.
(2) As can be seen from the data of example 1 and comparative examples 1-7, pinellia ternate, radix aconiti, rhizoma typhonii, rhubarb, chitosan and slow release auxiliary agent play a synergistic role in the preparation of analgesic moxibustion,the drug absorption efficiency of the analgesic moxibustion is synergistically improved because: the porous adsorbability of the chitosan provides attachment sites for the pinellia ternate, the monkshood, the rhizoma typhonii and the rheum officinale, so that the drug effects of the extracts of the pinellia ternate, the rhizoma typhonii and the rheum officinale and the monkshood are enhanced, and the comprehensive health-care efficacy of meridian moxibustion is effectively improved, wherein the pinellia ternate has the efficacies of promoting diuresis, eliminating dampness, clearing heat, cooling blood, regulating the middle warmer and benefiting the stomach and can neutralize the tonifying efficacy of the meridian moxibustion, so that the absorption of nutrient substances by a human body is milder, the rheum officinale is used for improving the immunity, the rhizoma typhonii can be used for enriching the blood, the comprehensive health-care efficacy of the meridian moxibustion can be effectively improved by applying the chitosan to the preparation of analgesic moxibustion, the pinellia ternate, the rhizoma typhonii and the rheum officinale contain rich tannin substances, the chitosan ensures that no precipitate is generated in the process of adding the pinellia ternate, the rhizoma typhonii and the rhe, is due to Mg2+The method is realized by fully exchanging octahedron and tetrahedron layers of cassava flour and chitosan. Because the same charges are carried among the rod crystals to form electrostatic repulsion, the rod crystals are prevented from agglomerating to achieve better dispersion effect, the viscosity is improved, chitosan is easy to dissolve in a weak acid solvent, the dissolved solution contains amino, the amino inhibits the activity of respiratory enzymes on the surface of bacteria by combining negative electrons, so that the bacteria are inactivated, meanwhile, because the porosity and the surface mass of hydroxyl of the chitosan are utilized, the donkey-hide gelatin, the cassava powder, the seaweed and the soybean lecithin play a synergistic role in preparing the slow release auxiliary agent, the medicine release efficiency and the absorption efficiency of the slow release auxiliary agent are synergistically improved, the donkey-hide gelatin serving as a traditional Chinese medicine has the effects of enriching blood, nourishing yin, moistening dryness and stopping bleeding and good viscosity, the cassava powder is starch extracted from the root tuber of a tropical plant, and because the ratio of amylopectin to amylose in the cassava native starch is as high as 80:20, therefore, the chitosan-containing slow-release agent has high peak viscosity, is used as a raw material for enhancing viscosity in a reinforcing system, is matched with donkey-hide gelatin, can improve the forming strength of the slow-release agent, enables the slow-release agent to keep a certain shape after entering an esophagus, enables medicines to be gradually absorbed by a human body, effectively improves the absorption efficiency of the medicine effect, and has higher egg contentWhite adsorption capacity; under the action of degrading enzyme, the chitosan has degradability; the chitosan is easy to be processed into lines and is suitable for being made into linear or sheet medical materials; the chitosan has affinity and solubility and is suitable for producing various derivatives; chitosan has higher chemical activity; the water binding capacity of the chitosan is high; in serum, chitosan is easily degraded and absorbed; chitosan has higher biodegradability; the chitosan shows the selective function of highly inhibiting the growth of oral streptococcus, does not influence the growth of other beneficial bacteria, and the porous adsorbability provides attachment sites for the donkey-hide gelatin, the cassava powder, the seaweed and the soybean lecithin, so that the donkey-hide gelatin, the cassava powder, the chitosan, the seaweed and the soybean lecithin can be used as a reinforcing system for preparing traditional Chinese medicine decoction pieces, and the reinforcing effect of the reinforcing system in the preparation of the slow-release auxiliary agent is improved, wherein the seaweed has the effects of clearing heat and softening and resolving hard mass and contains rich protein, and when the chitosan is used for preparing the slow-release auxiliary agent, the chitosan can effectively supplement the content of the protein of the traditional Chinese medicine decoction pieces, and can also effectively supplement inorganic elements such as sodium, potassium, iron, calcium and the like, vitamins B12, C and E, biotin and nicotinic acid, so that the health-care effect of the analgesic moxibustion of the invention is more reasonable, and the seaweed can be attached to the surface of the chitosan, so that the medicine is easier to be absorbed by the intestinal tract of the human body after entering the human body. The added soybean lecithin contains lecithin, cephalin and the like, has the effects of delaying senility, preventing cardiovascular and cerebrovascular diseases and the like, and can repair damaged cell membranes, improve the functions of the cell membranes, soften and age the cell membranes and increase the activity of the cells when being applied to the preparation of the analgesic moxibustion. The ingestion of lecithin can improve the metabolic capability, the self-healing capability and the regeneration capability of antibody tissues of human bodies and enhance the life vitality of the human bodies, thereby leading the nutrient components in the analgesic moxibustion to be fully absorbed by the human bodies.
[ detailed description ] embodiments
In order to facilitate a better understanding of the invention, the following examples are given to illustrate, but not to limit the scope of the invention.
In the embodiment, the analgesic moxibustion comprises the following raw materials in parts by weight: 40-90 parts of folium artemisiae argyi, 40-60 parts of wrinkled gianthyssop herb, 15-25 parts of semen brassicae, 4-8 parts of safflower, 2-8 parts of cinnamon, 1-8 parts of rhizoma atractylodis, 4-8 parts of mangnolia officinalis, 3-6 parts of agilawood, 2-5 parts of radix dipsaci, 5-15 parts of pinellia ternate, 4-8 parts of radix aconiti, 3-6 parts of rhizoma typhonii, 8-16 parts of rheum officinale, 6-9 parts of chitosan and 15-20 parts of slow-release auxiliary agent;
the slow release auxiliary agent is prepared by the following process: uniformly mixing 40-50 parts of rice hull powder, 15-25 parts of chitosan and distilled water according to parts by weight, uniformly stirring at the speed of 850-1050r/min, then adding 8-16 parts of donkey-hide gelatin, 4-8 parts of cassava powder, 3-9 parts of seaweed and 8-16 parts of soybean lecithin, stirring for 4-6h at the speed of 280-320r/min in a constant-temperature water bath at the temperature of 65-75 ℃, then cooling to room temperature, carrying out suction filtration to obtain a precipitate, drying the precipitate at the temperature of 45-55 ℃ for 44-52h, and cooling to room temperature to obtain the slow-release assistant.
The preparation method of the analgesic moxibustion comprises the following steps:
s1, cutting folium artemisiae argyi, agastache rugosus, semen brassicae, safflower, cinnamon, rhizoma atractylodis, mangnolia officinalis, agilawood and radix dipsaci, uniformly mixing, adding water, mixing, heating to 80-120 ℃, cooking for 20-40min, and then evaporating and concentrating to obtain a material a;
s2, uniformly mixing the material a, the pinellia ternate, the monkshood, the rhizoma typhonii, the rheum officinale, the chitosan and the slow-release auxiliary agent, heating to 80-90 ℃, centrifuging at the rotating speed of 1500-;
s3, concentrating the centrifugal glue solution in the S2, and then preparing the analgesic moxibustion with a strip-shaped structure in a rod making machine.
The present invention is illustrated by the following more specific examples.
Example 1
An analgesic moxibustion, which comprises the following raw materials by weight: 65 parts of folium artemisiae argyi, 50 parts of wrinkled gianthyssop, 20 parts of semen brassicae, 6 parts of safflower, 5 parts of cinnamon, 4.5 parts of rhizoma atractylodis, 6 parts of mangnolia officinalis, 4.5 parts of agilawood, 3.5 parts of dipsacus root, 10 parts of pinellia ternate, 6 parts of radix aconiti, 4.5 parts of rhizoma typhonii, 12 parts of rheum officinale, 7.5 parts of chitosan and 18 parts of slow-release auxiliary agent;
the slow release auxiliary agent is prepared by the following process: uniformly mixing 45 parts of rice hull powder, 20 parts of chitosan and distilled water according to parts by weight, uniformly stirring at a speed of 950r/min, then adding 12 parts of donkey-hide gelatin, 6.5 parts of cassava powder, 6 parts of seaweed and 12 parts of soybean lecithin, stirring for 5 hours at a speed of 300r/min in a constant-temperature water bath at 70 ℃, then cooling to room temperature, carrying out suction filtration to obtain a precipitate, drying the precipitate at 50 ℃ for 48 hours, and cooling to room temperature to obtain the slow-release auxiliary agent.
The preparation method of the analgesic moxibustion comprises the following steps:
s1, cutting folium artemisiae argyi, agastache rugosus, semen brassicae, safflower, cinnamon, rhizoma atractylodis, mangnolia officinalis, agilawood and radix dipsaci, uniformly mixing, adding water, mixing, heating to 80-120 ℃, cooking for 20-40min, and then evaporating and concentrating to obtain a material a;
s2, uniformly mixing the material a, the pinellia ternate, the monkshood, the rhizoma typhonii, the rheum officinale, the chitosan and the slow-release auxiliary agent, heating to 85 ℃, centrifuging at the rotating speed of 2000r/min for 2.5h, and removing impurities in the glue solution to obtain a centrifugal glue solution;
s3, concentrating the centrifugal glue solution in the S2, and then preparing the analgesic moxibustion with a strip-shaped structure in a rod making machine.
Example 2
An analgesic moxibustion, which comprises the following raw materials by weight: 40 parts of folium artemisiae argyi, 60 parts of agastache rugosus, 15 parts of semen brassicae, 8 parts of safflower, 2 parts of cinnamon, 8 parts of rhizoma atractylodis, 4 parts of mangnolia officinalis, 6 parts of agilawood, 2 parts of radix dipsaci from Sichuan of China, 15 parts of pinellia ternate, 4 parts of radix aconiti, 6 parts of rhizoma typhonii, 8 parts of rheum officinale, 9 parts of chitosan and 15 parts of slow-release auxiliary agent;
the slow release auxiliary agent is prepared by the following process: uniformly mixing 40 parts of rice hull powder, 25 parts of chitosan and distilled water according to parts by weight, uniformly stirring at the speed of 850r/min, then adding 16 parts of donkey-hide gelatin, 4 parts of cassava powder, 9 parts of seaweed and 8 parts of soybean lecithin, stirring for 6 hours at the speed of 280r/min in a constant-temperature water bath at 75 ℃, then cooling to room temperature, carrying out suction filtration to obtain a precipitate, then drying the precipitate at 45 ℃ for 52 hours, and cooling to room temperature to obtain the slow-release auxiliary agent.
The preparation method of the analgesic moxibustion comprises the following steps:
s1, chopping folium artemisiae argyi, agastache rugosus, semen brassicae, safflower, cinnamon, rhizoma atractylodis, mangnolia officinalis, agilawood and radix dipsaci, uniformly mixing, adding water, mixing, heating to 80 ℃, cooking for 40min, and then evaporating and concentrating to obtain a material a;
s2, uniformly mixing the material a, the pinellia ternate, the monkshood, the rhizoma typhonii, the rheum officinale, the chitosan and the slow-release auxiliary agent, heating to 80 ℃, centrifuging at the rotating speed of 2500r/min for 2 hours, and removing impurities in the glue solution to obtain a centrifugal glue solution;
s3, concentrating the centrifugal glue solution in the S2, and then preparing the analgesic moxibustion with a strip-shaped structure in a rod making machine.
Example 3
An analgesic moxibustion, which comprises the following raw materials by weight: 90 parts of folium artemisiae argyi, 40 parts of agastache rugosus, 25 parts of semen brassicae, 4 parts of safflower, 8 parts of cinnamon, 1 part of rhizoma atractylodis, 8 parts of mangnolia officinalis, 3 parts of agilawood, 5 parts of radix dipsaci from Sichuan of China, 5 parts of pinellia ternate, 8 parts of radix aconiti, 3 parts of rhizoma typhonii, 16 parts of rheum officinale, 6 parts of chitosan and 20 parts of slow-release auxiliary agent;
the slow release auxiliary agent is prepared by the following process: uniformly mixing 50 parts of rice hull powder, 15 parts of chitosan and distilled water according to parts by weight, uniformly stirring at the speed of 1050r/min, then adding 8 parts of donkey-hide gelatin, 8 parts of cassava powder, 3 parts of seaweed and 16 parts of soybean lecithin, stirring for 4 hours at the speed of 320r/min in a constant-temperature water bath at 65 ℃, then cooling to room temperature, carrying out suction filtration to obtain a precipitate, then drying the precipitate at 55 ℃ for 44 hours, and cooling to room temperature to obtain the slow-release auxiliary agent.
The preparation method of the analgesic moxibustion comprises the following steps:
s1, chopping folium artemisiae argyi, agastache rugosus, semen brassicae, safflower, cinnamon, rhizoma atractylodis, mangnolia officinalis, agilawood and radix dipsaci, uniformly mixing, adding water, mixing, heating to 120 ℃, cooking for 20min, and then evaporating and concentrating to obtain a material a;
s2, uniformly mixing the material a, the pinellia ternate, the monkshood, the rhizoma typhonii, the rheum officinale, the chitosan and the slow-release auxiliary agent, heating to 90 ℃, centrifuging at the rotating speed of 1500r/min for 3 hours, and removing impurities in the glue solution to obtain a centrifugal glue solution;
s3, concentrating the centrifugal glue solution in the S2, and then preparing the analgesic moxibustion with a strip-shaped structure in a rod making machine.
Comparative example 1
The preparation process is basically the same as that of example 1, except that raw materials for preparing analgesic moxibustion are lack of pinellia ternate, monkshood, rhizoma typhonii, rheum officinale, chitosan and slow release auxiliary agents.
Comparative example 2
The preparation process is basically the same as that of example 1, except that pinellia ternate is absent from the raw materials for preparing analgesic moxibustion.
Comparative example 3
The preparation process is basically the same as that of example 1, except that the raw materials for preparing the analgesic moxibustion are lack of radix aconiti.
Comparative example 4
The preparation process is basically the same as that of example 1, except that rhizoma Typhonii is absent from the raw materials for preparing analgesic moxibustion.
Comparative example 5
The preparation process is basically the same as that of example 1, except that rheum officinale is absent from the raw materials for preparing analgesic moxibustion.
Comparative example 6
The preparation process is basically the same as that of example 1, except that chitosan is absent in the raw materials for preparing analgesic moxibustion.
Comparative example 7
The preparation process is basically the same as that of example 1, except that the raw materials for preparing the analgesic moxibustion are lack of sustained-release auxiliary agents.
Comparative example 8
The moxibustion cream is prepared by adopting Chinese patent application document 'a moxibustion cream and a preparation method and application thereof (application number: 201610708042. X)' and the processes of examples 1-3.
Comparative example 9
The preparation process is basically the same as that of example 1, except that the raw materials for preparing the analgesic moxibustion comprise 4 parts of pinellia ternate, 9 parts of monkshood, 2 parts of rhizoma typhonii, 17 parts of rheum officinale, 5 parts of chitosan and 22 parts of sustained-release auxiliary agent.
Comparative example 10
The preparation process is basically the same as that of the example 1, except that the raw materials for preparing the analgesic moxibustion comprise 16 parts of pinellia ternate, 3 parts of monkshood, 2 parts of rhizoma typhonii, 17 parts of rhubarb, 4 parts of chitosan and 22 parts of sustained-release auxiliary agent.
Comparative example 11
The preparation process is basically the same as that of example 1, except that the raw materials for preparing the analgesic moxibustion comprise 4 parts of pinellia ternate, 10 parts of monkshood, 2 parts of rhizoma typhonii, 17 parts of rheum officinale, 3 parts of chitosan and 23 parts of sustained-release auxiliary agent.
The absorption rates of the analgesic moxibustion according to examples 1 to 3 and comparative examples 1 to 11 were measured, and the following measurement results were obtained:
Figure BDA0002376560770000111
from the above table, it can be seen that: (1) as can be seen from the data of examples 1-3 and comparative example 8, the absorption efficiency of the analgesic moxibustion of examples 1-3 of the present invention is significantly higher than that of the prior art; meanwhile, as can be seen from the data of examples 1 to 3, example 1 is the most preferred example.
(2) As can be seen from the data of example 1 and comparative examples 1 to 7, pinellia ternate, monkshood, rhizoma typhonii, rheum officinale, chitosan and sustained-release auxiliary agents play a synergistic role in the preparation of analgesic moxibustion, and the drug absorption efficiency of analgesic moxibustion is synergistically improved because: the porous adsorbability of the chitosan provides attachment sites for the pinellia ternate, the monkshood, the rhizoma typhonii and the rheum officinale, so that the drug effects of the extracts of the pinellia ternate, the rhizoma typhonii and the rheum officinale and the monkshood are enhanced, and the comprehensive health-care efficacy of meridian moxibustion is effectively improved, wherein the pinellia ternate has the efficacies of promoting diuresis, eliminating dampness, clearing heat, cooling blood, regulating the middle warmer and benefiting the stomach and can neutralize the tonifying efficacy of the meridian moxibustion, so that the absorption of nutrient substances by a human body is milder, the rheum officinale is used for improving the immunity, the rhizoma typhonii can be used for enriching the blood, the comprehensive health-care efficacy of the meridian moxibustion can be effectively improved by applying the chitosan to the preparation of analgesic moxibustion, the pinellia ternate, the rhizoma typhonii and the rheum officinale contain rich tannin substances, the chitosan ensures that no precipitate is generated in the process of adding the pinellia ternate, the rhizoma typhonii and the rhe, is due to Mg2+The method is realized by fully exchanging octahedron and tetrahedron layers of cassava flour and chitosan. Because the rod crystals have the same charges to form electrostatic repulsion, the rod crystals are prevented from agglomerating to achieve better dispersion effect, the viscosity is improved, and the viscosity is improved byThe chitosan is easy to dissolve in a weak acid solvent, the dissolved solution contains amino groups, the amino groups inhibit the activity of respiratory enzymes on the surface of bacteria by combining negative electrons, so that the bacteria are inactivated, meanwhile, due to the porosity of the chitosan and a large amount of hydroxyl groups on the surface, the donkey-hide gelatin, the cassava powder, the seaweed and the soybean lecithin play a synergistic role in preparing the slow-release auxiliary agent, the medicine release efficiency and the absorption efficiency of the slow-release auxiliary agent are synergistically improved, the donkey-hide gelatin serving as a traditional Chinese medicine has the effects of enriching blood, nourishing yin, moistening dryness and stopping bleeding and has good viscosity, the cassava powder is starch extracted from tuber roots of tropical plants, and as the ratio of amylopectin to amylose in the cassava raw starch is as high as 80:20, the cassava powder has high peak viscosity, and is used as a raw material for enhancing the viscosity in a reinforcing system and is matched with the donkey-hide gelatin, so that the molding strength of the slow, the sustained-release auxiliary agent keeps a certain shape after entering the esophagus, so that the medicine is gradually absorbed by a human body, the absorption efficiency of the medicine effect is effectively improved, and the chitosan has higher protein adsorption capacity; under the action of degrading enzyme, the chitosan has degradability; the chitosan is easy to be processed into lines and is suitable for being made into linear or sheet medical materials; the chitosan has affinity and solubility and is suitable for producing various derivatives; chitosan has higher chemical activity; the water binding capacity of the chitosan is high; in serum, chitosan is easily degraded and absorbed; chitosan has higher biodegradability; the chitosan shows a selective effect of highly inhibiting the growth of oral streptococcus, does not influence the growth of other beneficial bacteria, and provides attachment sites for the donkey-hide gelatin, the cassava powder, the seaweed and the soybean lecithin, so that the donkey-hide gelatin, the cassava powder, the chitosan, the seaweed and the soybean lecithin can be applied to the preparation of traditional Chinese medicine decoction pieces as a reinforcing system, and the reinforcing effect of the reinforcing system in the preparation of a slow-release auxiliary agent is improved, wherein the seaweed has the effects of clearing heat and softening and resolving hard mass, and contains abundant proteins, and when the chitosan is applied to the preparation of the slow-release auxiliary agent, the chitosan can effectively supplement the content of the proteins of the traditional Chinese medicine decoction pieces, and can also effectively supplement inorganic elements such as sodium, potassium, iron, calcium and the like, vitamins B12, C and E, biotin and nicotinic acid, so that the health-care effect of the analgesic moxibustion of the invention is realizedMore reasonable, and the seaweed can be attached to the surface of the chitosan, so that the seaweed is easier to be absorbed by intestinal tracts of a human body after entering the human body. The added soybean lecithin contains lecithin, cephalin and the like, has the effects of delaying senility, preventing cardiovascular and cerebrovascular diseases and the like, and can repair damaged cell membranes, improve the functions of the cell membranes, soften and age the cell membranes and increase the activity of the cells when being applied to the preparation of the analgesic moxibustion. The ingestion of lecithin can improve the metabolic capability, the self-healing capability and the regeneration capability of antibody tissues of human bodies and enhance the life vitality of the human bodies, thereby leading the nutrient components in the analgesic moxibustion to be fully absorbed by the human bodies.
The above description should not be taken as limiting the invention to the embodiments, but rather, as will be apparent to those skilled in the art to which the invention pertains, numerous simplifications or substitutions may be made without departing from the spirit of the invention, which shall be deemed to fall within the scope of the invention as defined by the claims appended hereto.

Claims (8)

1. The preparation method of the analgesic moxibustion is characterized by comprising the following steps:
s1, cutting folium artemisiae argyi, agastache rugosus, semen brassicae, safflower, cinnamon, rhizoma atractylodis, mangnolia officinalis, agilawood and radix dipsaci, uniformly mixing, adding water, mixing, heating to 80-120 ℃, cooking for 20-40min, and then evaporating and concentrating to obtain a material a;
s2, uniformly mixing the material a, the pinellia ternate, the monkshood, the rhizoma typhonii, the rheum officinale, the chitosan and the slow-release auxiliary agent, heating to 80-90 ℃, centrifuging at the rotating speed of 1500-;
s3, concentrating the centrifugal glue solution in the S2, and then preparing the analgesic moxibustion with a strip-shaped structure in a rod making machine.
2. The method for preparing analgesic moxibustion as claimed in claim 1, wherein the analgesic moxibustion comprises the following raw materials: folium artemisiae argyi, agastache rugosus, semen brassicae, safflower, cinnamon, rhizoma atractylodis, mangnolia officinalis, agilawood, radix dipsaci, pinellia ternate, radix aconiti, rhizoma typhonii, rheum officinale, chitosan and a slow-release auxiliary agent.
3. The method for preparing analgesic moxibustion as claimed in claim 2, wherein the sustained release adjuvant comprises the following raw materials: rice hull powder, chitosan, donkey-hide gelatin, tapioca, seaweed and soybean lecithin.
4. The method for preparing analgesic moxibustion as claimed in claim 2, wherein the weight ratio of pinellia ternate, monkshood, rhizoma typhonii, rheum officinale, chitosan and sustained release auxiliary agent is (5-15): 4-8): 3-6): 8-16): 6-9): 15-20.
5. The method for preparing analgesic moxibustion according to claim 4, wherein the weight ratio of the pinellia tuber, the common monkshood mother root, the giant typhonium rhizome, the rhubarb, the chitosan and the slow release auxiliary agent is 10.5:5.8:4.7:13.2:7.4: 18.6.
6. The method for preparing analgesic moxibustion as claimed in claim 1, characterized in that the analgesic moxibustion comprises the following raw materials in parts by weight: 40-90 parts of folium artemisiae argyi, 40-60 parts of wrinkled gianthyssop herb, 15-25 parts of semen brassicae, 4-8 parts of safflower, 2-8 parts of cinnamon, 1-8 parts of rhizoma atractylodis, 4-8 parts of mangnolia officinalis, 3-6 parts of agilawood, 2-5 parts of radix dipsaci, 5-15 parts of pinellia ternate, 4-8 parts of radix aconiti, 3-6 parts of rhizoma typhonii, 8-16 parts of rheum officinale, 6-9 parts of chitosan and 15-20 parts of slow-release auxiliary agent.
7. The method for preparing analgesic moxibustion according to claim 3, characterized in that the sustained release adjuvant comprises the following raw materials in parts by weight: 40-50 parts of rice hull powder, 15-25 parts of chitosan, 8-16 parts of donkey-hide gelatin, 4-8 parts of cassava powder, 3-9 parts of seaweed and 8-16 parts of soybean lecithin.
8. The method for preparing analgesic moxibustion as claimed in claim 7, wherein the sustained release adjuvant is prepared by the following process: uniformly mixing rice hull powder, chitosan and distilled water, uniformly stirring at the speed of 850-1050r/min, then adding donkey-hide gelatin, cassava powder, seaweed and soybean lecithin, stirring for 4-6h at the speed of 280-320r/min in a constant-temperature water bath at the temperature of 65-75 ℃, then cooling to room temperature, carrying out suction filtration to obtain a precipitate, drying the precipitate at the temperature of 45-55 ℃ for 44-52h, and cooling to room temperature to obtain the slow-release auxiliary agent.
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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103099890A (en) * 2013-02-28 2013-05-15 赵文慧 Formula of traditional Chinese medicine moxibustion
CN106214718A (en) * 2016-08-23 2016-12-14 美颜世家国际化妆品(北京)有限公司 A kind of moxa-moxibustion cream and its preparation method and application
CN107550982A (en) * 2017-09-25 2018-01-09 冯卓 A kind of Chinese medicine composition and the moxa-moxibustion medicine for treating disadvantage disease
CN108498694A (en) * 2018-03-19 2018-09-07 长沙秋点兵信息科技有限公司 Traditional Chinese medicine decoction pieces and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103099890A (en) * 2013-02-28 2013-05-15 赵文慧 Formula of traditional Chinese medicine moxibustion
CN106214718A (en) * 2016-08-23 2016-12-14 美颜世家国际化妆品(北京)有限公司 A kind of moxa-moxibustion cream and its preparation method and application
CN107550982A (en) * 2017-09-25 2018-01-09 冯卓 A kind of Chinese medicine composition and the moxa-moxibustion medicine for treating disadvantage disease
CN108498694A (en) * 2018-03-19 2018-09-07 长沙秋点兵信息科技有限公司 Traditional Chinese medicine decoction pieces and preparation method thereof

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