CN111084833A - Medicine for treating neurodermatitis and eczema and preparation method thereof - Google Patents

Medicine for treating neurodermatitis and eczema and preparation method thereof Download PDF

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CN111084833A
CN111084833A CN202010136251.8A CN202010136251A CN111084833A CN 111084833 A CN111084833 A CN 111084833A CN 202010136251 A CN202010136251 A CN 202010136251A CN 111084833 A CN111084833 A CN 111084833A
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parts
root
medicine
eczema
neurodermatitis
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王吉坤
王冬青
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
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Abstract

The invention discloses a medicament for treating neurodermatitis and eczema and a preparation method thereof, wherein the medicament comprises the following components in parts by weight: 20-40 parts of paniculate swallowwort root, 10-20 parts of radix euphorbiae lantu, 10-20 parts of common andrographis herb, 15-25 parts of angelica sinensis, 20-40 parts of silkworm excrement, 20-40 parts of sambucus chinensis, 20-40 parts of caulis piperis nigri, 15-25 parts of caulis spatholobi, 5-15 parts of periostracum cicadae, 15-25 parts of burdock, 15-25 parts of schizonepeta, 15-25 parts of divaricate saposhnikovia root, 5-15 parts of realgar, 10-20 parts of alum, 10-20 parts of cortex lycii radicis, 10-20 parts of radix angelicae pubescentis, 10-20 parts of ephedra, 15-25 parts of mint, 15-25 parts of pomegranate bark, 15-25 parts of radix sophorae flavescentis, 10-20 parts of cortex dictamni, 15-25 parts; the medicine has antibacterial and antipruritic effects, and has remarkable therapeutic effect on neurodermatitis.

Description

Medicine for treating neurodermatitis and eczema and preparation method thereof
Technical Field
The invention relates to a medicine for treating neurodermatitis and eczema and a preparation method thereof, belonging to the technical field of external medicines for skin diseases.
Background
Neurodermatitis is also called as chronic simple lichen, is a chronic skin disease characterized by paroxysmal skin pruritus and skin lichen, is a common skin disease and is commonly seen in adults. It is good at the two sides of the neck, nape, elbow, popliteal fossa, sacrococcygeal region, wrist, ankle, and also at the lumbar and back, eyelids, four limbs, and vulva. The patient often scratches due to paroxysmal severe itching, pimples are gradually increased and are fused into pieces after long time, the disease is a chronic disease, the symptoms are mild and severe, the life is rarely threatened, but the disease is stubborn and difficult to cure, the pain of the patient is lingering, and the disease is easy to relapse after being cured, so that the disease is a great medical problem.
Eczema is a skin inflammation which has the tendency of polymorphous rash and exudation and is easy to recur. It can be divided into three types of acute, subacute and chronic. The rash can occur on any part of the body surface, usually on the exposed parts of the head, face and extremities, the pudendum and anus, and is mostly distributed symmetrically, so that the patient feels burning and itching, and the rash often occurs repeatedly.
Disclosure of Invention
In order to overcome the defects of the prior art, the invention provides a medicament for treating neurodermatitis and eczema and a preparation method thereof, and the medicament has the functions of sterilizing and relieving itching and has obvious curative effect on the neurodermatitis.
The invention is realized by the following technical scheme:
the medicine for treating neurodermatitis and eczema comprises the following components in parts by weight:
20-40 parts of paniculate swallowwort root, 10-20 parts of radix euphorbiae lantu, 10-20 parts of common andrographis herb, 15-25 parts of angelica sinensis, 20-40 parts of silkworm excrement, 20-40 parts of Chinese forgetmenot root, 20-40 parts of caulis piperis, 15-25 parts of suberect spatholobus stem, 5-15 parts of cicada slough, 15-25 parts of great burdock achene, 15-25 parts of fineleaf schizonepeta herb, 15-25 parts of divaricate saposhnikovia root, 5-15 parts of realgar, 10-20 parts of alum, 10-20 parts of cortex lycii radicis, 10-20 parts of radix angelicae pubescentis, 10-20 parts of ephedra, 15-25 parts of mint, 15-25 parts of pomegranate bark, 15-25 parts of lightyellow sophora root, 10-20 parts of dittany bark.
Preferably, the medicine for treating neurodermatitis and eczema comprises the following components in parts by weight:
25-35 parts of paniculate swallowwort root, 12-18 parts of radix euphorbiae lantu, 12-18 parts of common andrographis herb, 18-22 parts of angelica tail, 25-35 parts of silkworm excrement, 25-35 parts of Chinese forgetmenot root, 25-35 parts of glaucescent fissistigma root, 18-22 parts of suberect spatholobus stem, 8-12 parts of cicada slough, 15-22 parts of great burdock achene, 18-22 parts of fineleaf schizonepeta herb, 18-22 parts of divaricate saposhnikovia root, 8-12 parts of realgar, 12-17 parts of alum, 12-17 parts of cortex lycii radicis, 12-17 parts of radix angelicae pubescentis, 12-17 parts of ephedra herb, 18-22 parts of mint, 18-22 parts of pomegranate bark, 18-22 parts of lightyellow sophora root, 12-17.
The preparation method of the medicine for treating neurodermatitis and eczema comprises the following steps:
1) weighing the traditional Chinese medicinal materials of paniculate swallowwort root, radix euphorbiae lantu, common andrographis herb, angelica tail, silkworm excrement, sambucus chinensis, glaucescent fissistigma root, suberect spatholobus stem, cicada slough, great burdock achene, fineleaf schizonepeta herb, divaricate saposhnikovia root, realgar, alum, cortex lycii radicis, radix angelicae pubescentis, ephedra, mint, pomegranate bark, lightyellow sophora root, dittany bark, chaulmoogra seed and pseudolarix, cleaning, mixing, crushing, particularly smashing the chaulmoogra seed, adding 5-8 times of water, soaking for 0.5-1 hour, decocting with strong fire for 20-30 minutes;
2) repeating the decocting process of step 1) for 2-4 times, wherein the amount of water added each time is 5-8 times of that of the raw material medicinal materials, and mixing the decoctions obtained by multiple times of decocting.
A method for using a medicament for treating neurodermatitis and eczema comprises the following steps:
1) cooling the medicinal liquid to 15-20 deg.C to obtain cooled medicinal liquid;
2) preparing multiple layers of gauze according to the size and shape of skin lesion of the affected part, soaking in the medicinal liquid, dipping in the cooled medicinal liquid, and wet-compressing on the affected part, changing the gauze every 3-5 minutes, dipping in the medicinal liquid for each time, wet-compressing for 20-30 minutes for each time, and treating for 1-2 times per day.
The gauze dipped with the liquid medicine in the wet dressing process is based on the condition that the liquid medicine does not drip. The gauze dipped with the liquid medicine can also be replaced by a pure cotton towel.
A preparation method of a medicine for treating neurodermatitis and eczema comprises the following steps:
1) weighing the traditional Chinese medicinal materials of cynanchum paniculatum, radix euphorbiae lantu, common andrographis herb, angelica tail, silkworm excrement, sambucus chinensis, glaucescent fissistigma root, suberect spatholobus stem, cicada slough, great burdock achene, schizonepeta, divaricate saposhnikovia root, realgar, alum, cortex lycii radicis, radix angelicae pubescentis, ephedra, mint, pomegranate bark, lightyellow sophora root, cortex dictamni, chaulmoogra seed and pseudolarix, cleaning, mixing, crushing into 50-100 meshes of fine powder, adding 5-8 times of ethanol solution, soaking for 7-15 days;
2) repeating the extraction process of step 1) for 2-4 times, wherein the amount of ethanol added each time is 2-3 times of that of the raw materials, and mixing the medicinal liquids obtained by multiple extractions to obtain tincture.
Preferably, the ethanol solution is alcohol with a concentration of 75% or more.
Compared with the prior art, the invention has the following beneficial effects:
the medicine for treating neurodermatitis and eczema is an external preparation, adopts the treatment principles of clearing heat, promoting diuresis, dispelling wind and arresting itching, mainly kills various bacteria and fungi, takes insect killing and itching relieving effects into consideration, has obvious curative effects on neurodermatitis, acne, scabies, tinea versicolor, tinea manus, tinea pedis, onychomycosis, tinea versicolor, tinea corporis, tinea cruris and the like, has low preparation cost, and can reduce the economic burden of patients. The medicine is prepared from pure traditional Chinese medicines, keeps the characteristics of small toxicity and good curative effect of natural medicines, has definite curative effect and convenient use, gradually releases the medicines after external application, plays a role in treatment and can ensure that the contained medicines are absorbed in a balanced way to generate the curative effect.
Detailed Description
The present invention will be described in further detail with reference to specific examples, but the scope of the present invention is not limited to these examples, and all changes or equivalent substitutions that do not depart from the spirit of the present invention are intended to be included within the scope of the present invention.
Example 1
The medicine for treating neurodermatitis and eczema comprises the following components in parts by weight:
20 parts of paniculate swallowwort root, 10 parts of radix euphorbiae lantu, 10 parts of common andrographis herb, 15 parts of angelica tail, 20 parts of silkworm excrement, 20 parts of sambucus chinensis, 20 parts of glaucescent fissistigma root, 15 parts of suberect spatholobus stem, 5 parts of cicada slough, 15 parts of great burdock achene, 15 parts of fineleaf schizonepeta herb, 15 parts of divaricate saposhnikovia root, 5 parts of realgar, 10 parts of alum, 10 parts of cortex lycii radicis, 10 parts of radix angelicae pubescentis, 10 parts of ephedra, 15 parts of mint, 15 parts of pomegranate bark, 15 parts of radix sophorae flavescen.
Example 2
The medicine for treating neurodermatitis and eczema comprises the following components in parts by weight:
40 parts of paniculate swallowwort root, 10 parts of radix euphorbiae lantu, 20 parts of common andrographis herb, 25 parts of angelica tail, 40 parts of silkworm excrement, 40 parts of sambucus chinensis, 40 parts of glaucescent fissistigma root, 25 parts of suberect spatholobus stem, 15 parts of cicada slough, 25 parts of great burdock achene, 25 parts of fineleaf schizonepeta herb, 25 parts of divaricate saposhnikovia root, 15 parts of realgar, 20 parts of alum, 20 parts of cortex lycii radicis, 20 parts of radix angelicae pubescentis, 20 parts of ephedra, 25 parts of mint, 25 parts of pomegranate bark, 25 parts of radix sophorae flavescen.
Example 3
The medicine for treating neurodermatitis and eczema comprises the following components in parts by weight:
30 parts of paniculate swallowwort root, 15 parts of radix euphorbiae lantu, 15 parts of common andrographis herb, 20 parts of angelica tail, 30 parts of silkworm excrement, 30 parts of sambucus chinensis, 30 parts of glaucescent fissistigma root, 20 parts of suberect spatholobus stem, 10 parts of cicada slough, 20 parts of great burdock achene, 20 parts of fineleaf schizonepeta herb, 20 parts of divaricate saposhnikovia root, 10 parts of realgar, 15 parts of alum, 15 parts of cortex lycii radicis, 15 parts of radix angelicae pubescentis, 15 parts of ephedra, 20 parts of mint, 20 parts of pomegranate bark, 20 parts of radix sophorae flavescen.
Example 4
The medicine for treating neurodermatitis and eczema comprises the following components in parts by weight:
35 parts of paniculate swallowwort root, 18 parts of radix euphorbiae lantu, 18 parts of common andrographis herb, 18 parts of angelica tail, 25 parts of silkworm excrement, 25 parts of sambucus chinensis, 35 parts of glaucescent fissistigma root, 22 parts of suberect spatholobus stem, 8 parts of cicada slough, 15 parts of great burdock achene, 22 parts of schizonepeta, 18 parts of divaricate saposhnikovia root, 8 parts of realgar, 12 parts of alum, 17 parts of cortex lycii radicis, 17 parts of radix angelicae pubescentis, 12 parts of ephedra herb, 18 parts of mint, 22 parts of pomegranate bark, 22 parts of radix sophorae flavescentis.
Example 5
The medicine for treating neurodermatitis and eczema comprises the following components in parts by weight:
25 parts of paniculate swallowwort root, 12 parts of radix euphorbiae lantu, 12 parts of common andrographis herb, 22 parts of angelica tail, 35 parts of silkworm excrement, 35 parts of sambucus chinensis, 25 parts of glaucescent fissistigma root, 18 parts of suberect spatholobus stem, 12 parts of cicada slough, 22 parts of great burdock achene, 18 parts of schizonepeta, 122 parts of divaricate saposhnikovia root, 12 parts of realgar, 17 parts of alum, 12 parts of cortex lycii radicis, 12 parts of radix angelicae pubescentis, 17 parts of ephedra herb, 22 parts of mint, 18 parts of pomegranate bark, 18 parts of radix sophorae flavescentis.
Example 6
The medicine for treating neurodermatitis and eczema comprises the following components in parts by weight:
30 parts of paniculate swallowwort root, 15 parts of radix euphorbiae lantu, 15 parts of common andrographis herb, 20 parts of angelica tail, 30 parts of silkworm excrement, 30 parts of sambucus chinensis, 30 parts of glaucescent fissistigma root, 20 parts of suberect spatholobus stem, 10 parts of cicada slough, 20 parts of great burdock achene, 20 parts of fineleaf schizonepeta herb, 20 parts of divaricate saposhnikovia root, 10 parts of realgar, 15 parts of alum, 15 parts of cortex lycii radicis, 15 parts of radix angelicae pubescentis, 15 parts of ephedra, 20 parts of mint, 20 parts of pomegranate bark, 20 parts of radix sophorae flavescentis, 15 parts of cortex dictamni.
Example 7
The medicine for treating neurodermatitis and eczema comprises the following components in parts by weight:
30 parts of paniculate swallowwort root, 15 parts of radix euphorbiae lantu, 15 parts of common andrographis herb, 20 parts of angelica tail, 30 parts of silkworm excrement, 30 parts of sambucus chinensis, 30 parts of glaucescent fissistigma root, 20 parts of suberect spatholobus stem, 15 parts of orientvine stem, 10 parts of cicada slough, 20 parts of great burdock achene, 20 parts of fineleaf schizonepeta herb, 20 parts of divaricate saposhnikovia root, 10 parts of realgar, 15 parts of alum, 15 parts of Chinese wolfberry root-bark, 15 parts of doubleteeth pubescent angelica root, 15 parts of ephedra herb, 20 parts of mint, 20 parts of pomegranate bark, 20 parts of lightyellow sophora root, 15 parts of dittan.
Example 8
The medicine for treating neurodermatitis and eczema comprises the following components in parts by weight:
30 parts of paniculate swallowwort root, 15 parts of radix euphorbiae lantu, 15 parts of common andrographis herb, 20 parts of angelica tail, 30 parts of silkworm excrement, 30 parts of sambucus chinensis, 30 parts of glaucescent fissistigma root, 20 parts of suberect spatholobus stem, 15 parts of orientvine stem, 10 parts of cicada slough, 20 parts of great burdock achene, 20 parts of fineleaf schizonepeta herb, 20 parts of divaricate saposhnikovia root, 10 parts of realgar, 15 parts of alum, 15 parts of Chinese wolfberry root-bark, 15 parts of doubleteeth pubescent angelica root, 15 parts of ephedra herb, 25 parts of mint, 20 parts of pomegranate bark, 20 parts of lightyellow sophora root, 15 parts of dittan.
Paniculate swallowwort root, pungent in flavor and warm in nature, enters liver and stomach meridians. It has the actions of dispelling wind and dampness, relieving pain and itching. Mainly used for treating rheumatic arthralgia, stomachache and fullness, toothache, lumbago, traumatic injury, urticaria and eczema.
Lang Du Si is pungent, bitter and neutral. Is toxic. Disperse pathogen accumulation, expel water, alleviate pain, kill parasites. For swelling of water and gas, tuberculous lymphadenitis; it is used externally to kill fly and maggot.
Andrographis, bitter and cold; it enters heart, lung, large intestine and bladder meridians. Has the effects of clearing away heat and toxic materials, cooling blood, relieving swelling, and eliminating dampness. Can be used for treating wind-heat common cold, early stage of epidemic febrile disease, cough and asthma due to lung heat, lung abscess with pus discharge, sore throat, damp-heat dysentery, pyretic stranguria with astringency, pruritus due to heat eruption, carbuncle, swelling, sore, and snake and insect bite.
The root of Chinese angelica, radix Angelicae sinensis, pungent, sweet and warm in nature, can enrich blood, promote blood circulation, regulate menstruation, relieve pain and moisten intestines. The tail of the body can dilate blood vessels, reduce vascular resistance, increase circulating blood volume and contribute to local circulation of the skin.
Silkworm excrement is pungent in flavor and warm in nature, and can dispel wind-damp and alleviate pain. Silkworm excrement has dryness, and the dryness medicine can surpass wind and eliminate dampness, so silkworm excrement can expel wind on skin.
Jiugan forgetfulroot, sweet and bitter in flavor, neutral in nature. Mainly used for dispelling wind and promoting diuresis; promoting blood circulation; stopping bleeding. Chief wind-damp arthralgia; gout; Kaschin-Beck disease; acute and chronic nephritis; rubella; traumatic injury; swelling and pain of fracture; bleeding due to trauma.
Caulis Marsdeniae Tenacissimae, expelling pathogenic wind and regulating meridians; promoting blood circulation to arrest pain; induce diuresis to alleviate edema. It can not only relieve itching, but also eliminate pimple on human body, when people usually have rubella, urticaria, eczema and other common skin diseases, the traditional Chinese medicine caulis polygoni multiflori, the common cnidium fruit, the belvedere fruit and other traditional Chinese medicine steelyard can be decocted together for external washing,
the caulis spatholobi is bitter in taste, slightly sweet and warm in nature, enters liver, heart and kidney channels, is red in color, enters blood, moistens the body and disperses, and has the effects of activating blood, relaxing muscles and tendons, nourishing blood and regulating menstruation; can be used for treating disharmony of channels and collaterals, rubella, eczema, skin itching, freckle acne, acne rosacea, pyocutaneous disease, pyogenic infection, dermatophytosis, and scabies caused by damp-heat and blood dryness.
Qingfengteng, bitter and pungent in flavor and mild in nature. Dispel wind-damp, treat fatigue, alleviate pain, induce diuresis. It can be used for treating rheumatic osteodynia, bone pain due to fatigue, common cold, cough, stomach qi pain, skin prurigo, and edema. The caulis sinomenii treats all kinds of wind, and the formula is combined with the lightyellow sophora root, the dittany bark and the divaricate saposhnikovia root, has the effects of resisting inflammation, dredging the channels and collaterals, relieving pain and calming, and treats the skin pruritus caused by rheumatism.
Cicada slough is sweet and cold. Dispel wind and remove heat, relieve sore throat, promote eruption, remove nebula and relieve spasm.
Burdock fruit, fructus Arctii, pungent and bitter, cool. Disperse wind-heat, ventilate lung and promote eruption, resolve swelling and remove toxicity. It is indicated for cough due to wind-heat, sore throat, impenetrable macula, itching rubella, carbuncle, swelling and sore. The fructus Arctii decoction has inhibitory effect on Staphylococcus aureus, Nocardia stellatodes, epidermophyton inguinal, etc. The cicada slough has the function of clearing heat after being spread, and the cicada slough is used together with the great burdock achene and the mint to dispel wind-heat and treat pruritus of the skin caused by wind-qi.
Schizonepeta, Teng, pungent and warm. Relieving exterior syndrome, dispelling pathogenic wind, and regulating blood; stir-baked to charcoal to stop bleeding. Treating common cold, fever, headache, sore throat, vomiting, hematemesis, epistaxis, and hematochezia; metrorrhagia and metrostaxis, postpartum anemic fainting; abscess, sores and scabies, scrofula.
Ledebouriella root, pungent and sweet. Relieve exterior syndrome, dispel wind, subdue dampness and stop spasm.
Realgar, pungent and warm in nature. It enters liver and large intestine meridians; detoxify and kill parasites, dry dampness and dispel phlegm, check malaria. Realgar has inhibitory effect on Staphylococcus aureus, Pseudomonas aeruginosa, various dermatophytes, and human type and bovine type tubercle bacillus. Has obvious curative effect on herpes zoster, chronic granulocytic leukemia and chronic bronchitis.
Alum, sour, astringent and cold. Externally used for detoxifying and killing parasites, eliminating dampness and relieving itching; orally administered to stop bleeding and check diarrhea, dispel wind-phlegm. The external treatment is used for eczema, mange and purulent pus in purulent otitis media; it is orally administered for treating chronic diarrhea, hematochezia, metrorrhagia, epilepsy, and mania.
Cortex Lycii, sweet and cold. Cool blood and clear heat, purge fire and diminish inflammation, dispel wind. The herb of rehmannia is sweet in taste and cold in nature, and can be used together with periostracum Cicadae to effectively dispel wind and heat, and treat skin fever and itch.
Du Huo is pungent, bitter and slightly warm. Can stop wind-moving, bleed air, remove bone poisoning, remove arthralgia and dampness, dispel wind and remove dampness, promote blood circulation to reduce swelling, and draw out diseased qi. In the recipe, the radix angelicae pubescentis is combined with the radix sileris, the angelica dahurica and the like to dispel rheumatism, promote qi circulation and activate blood.
Ma Huang is pungent, bitter and warm. Dispersing lung qi and going exterior, skin itch due to wind pathogen not dispersing, stagnation transforming into fire, lying under the skin, ephedra herb releases stagnated heat, disperses pathogenic toxin, and itch stopping when pathogen is removed.
Mint, pungent in flavor and cool in nature. It enters lung and liver meridians and has the functions of dispersing wind-heat, clearing away heat and toxic material, dispersing stagnated liver qi, relieving depression and itching, etc.
Pomegranate rind, sour, astringent and warm. Astringe intestines to check diarrhea, stop bleeding, expel parasites. The pericarpium Granati contains abundant substances, and has effects of healing topical wound or protecting topical part from irritation, and also has antibacterial and antiviral effects.
Ku Shen is bitter and cold. Clear heat, dry dampness and kill parasites. It is used to treat dysentery due to heat and blood, intestinal wind, jaundice, leucorrhea with red and white discharge, infantile pneumonia, malnutritional stagnation, acute tonsillitis, anal fistula, rectocele, skin pruritus, scabies, malignant sore, eczema and pruritus vulvae, scrofula, and scald.
Dittany bark, bitter and cold; has the functions of clearing heat and drying dampness, dispelling wind and arresting itching and detoxifying. Mainly treats rubella, eczema, scabies and tinea caused by wind-heat and damp toxin; arthralgia due to damp-heat. The recipe is combined with flavescent sophora root and ledebouriella root, and can clear heat and dry dampness, dispel wind and relieve arthralgia.
Da Feng Zi is pungent, hot and toxic. Dispel wind and dry dampness, counteract toxic pathogen and kill parasites. It is used externally to treat toxic sore, scabies, tinea, chapped hand and back.
Cortex pseudolaricis, bitter, pungent and warm, has effects of killing parasites and relieving itching, and can be used for treating tinea corporis, tinea pedis, scabies, eczema and neurodermatitis.
Dahurian angelica root, pungent and warm. Dispel wind, dry dampness, resolve swelling and alleviate pain. It is used to treat headache, toothache, nasosinusitis, cold-dampness, abdominal pain, intestinal wind, hemorrhoid, carbuncle, cellulitis, pyocutaneous disease, skin dryness, pruritus, and scabies. The decoction of radix Angelicae Dahuricae has inhibitory effect on Escherichia coli, dysentery bacillus, Bacillus proteus, typhoid bacillus, paratyphoid bacillus, Pseudomonas aeruginosa, Vibrio cholerae, and human type tubercle bacillus.
Neurodermatitis is mainly skin itch which is considered as wind by traditional Chinese medicine. The disease can be clinically classified into three types: the initial onset is mostly wind-heat stagnation, followed by exuberant blood-heat and wind-dryness after a long time. In the initial stage, the symptoms are relieved by external attack of wind evil and only skin pruritus. This stage is generally unnoticed. Some people love to eat greasy food at ordinary times, the dampness and heat of the spleen and the stomach are bred, the dampness and heat is nowhere to be released, and the skin is itchy, which is the dampness and heat of the spleen and the stomach. The disease condition continues to develop, the damp-heat in the spleen and the stomach can cause deficiency of qi and blood, the blood deficiency can transform into dryness and generate wind to cause skin itch, the skin itch is generally severe at night, the disease condition is complicated, and the damp-heat in the spleen and the stomach and the blood dryness generate wind. The skin diseases are mainly caused by the disturbance of the mood and the endogenous heart fire. Has clinical manifestations of skin pruritus, and can be used for comprehensive treatment by heat-clearing and detoxicating, promoting blood circulation for removing blood stasis, and resisting allergy.
The formula has the effects of expelling wind and removing dampness, promoting qi circulation and activating blood circulation, dredging the channels and collaterals and drawing out viruses. The paniculate swallowwort root is used as a monarch drug, and has the effects of promoting qi circulation, relieving pain and relieving itching due to pungent and warm properties; herba Andrographitis and cortex Lycii have effects of clearing heat and detoxicating, cooling blood and arresting hemorrhage, cortex Dictamni Radicis, caulis Piperis Futokadsurae, caulis Sinomenii and caulis Marsdeniae Tenacissimae have effects of dispelling pathogenic wind, dredging collaterals and relieving itching, and radix Angelicae sinensis and herba Seu radix Phrymatis have effects of promoting blood circulation and can be used as ministerial drugs; herba Schizonepetae, radix Saposhnikoviae, periostracum Cicadae, and radix Angelicae Pubescentis for dispelling pathogenic wind, promoting diuresis, and relieving itching, semen Hydnocarpi, radix Angelicae Dahuricae, Realgar, and Alumen for clearing heat and eliminating dampness, radix Sophorae Flavescentis for promoting diuresis and eliminating dampness, and herba Ephedrae for promoting diuresis and detumescence as adjuvant drugs; the skin itch is caused by the fact that wind pathogen does not disperse and fire is transformed from stagnation to subdermal, the ephedra and the mint are used as guiding drugs, the ephedra ventilates the lung and walks outward, stagnated heat is released, pathogenic toxin is dispersed, pathogenic factors are led out, and the itch is stopped when the pathogenic factors are removed. The mint has the functions of promoting the penetration of various medicines, promoting the transdermal absorption of the various medicines, helping the external medicine to directly reach the focus, directly absorbing from the focus and treating both symptoms and root causes.
The wet compress can utilize the liquid medicine to directly act on the affected part, thereby achieving the purpose of rapidly astringing the liquid seepage of the affected part, thereby reducing the seepage and promoting the inflammation to subside.
The invention uses the cooled liquid medicine to be directly applied to the damaged skin, and the low-temperature liquid medicine can cause the peripheral blood vessels of the local skin to contract, thereby reducing hyperemia and exudation, playing the functions of calming, relieving itching and rapidly converging, and relieving subjective symptoms of patients.
In the wet dressing process, the gauze for wet dressing can absorb exudates and purulent exudates on the surface of the skin lesion, soften and remove crusts and other attachments on the surface of the skin lesion, and plays a role in cleaning while wet dressing. And the wet compress can isolate the stimulation of the outside to the skin damage, and reduce the influence of bacteria to the skin damage. The gauze in the wet compress process can be replaced by a towel.
The skin swelling and skin damage with erosive effusion caused by neurodermatitis and eczema can be applied by wet compress, and the skin diseases with poor blood circulation are not suitable for wet compress.
The medicine can also be prepared into tincture, the raw material medicines are weighed and mixed according to a proportion and soaked in 3-5 times of alcohol, the alcohol is alcohol with the concentration of over 75 percent and is soaked for 7-15 days, and liquid is taken to obtain the tincture. The tincture is suitable for treating various pruritic skin diseases. However, the tincture is forbidden for acute inflammation and erosion exudation type skin damage, and is not suitable for dry skin, chapped skin damage, skin wrinkle part and mucosa.
When in use, the medicine liquid is directly applied to the affected part twice a day by dipping the cotton stick. The alcohol has effects of sterilizing, relieving itching, dissolving sebum, inhibiting sebum secretion, loosening epidermis, absorbing water in skin, relaxing muscles and tendons, promoting blood circulation, dilating peripheral blood vessel, enhancing permeability of peripheral blood vessel, and promoting absorption of medicine. The effect of alcohol is matched with the medicine, and the heat dissipation and sedation effects can be achieved through volatilization of alcohol.
The medicine can also be prepared into paste, the raw materials are weighed and mixed according to the proportion, the mixture is smashed into medicine powder, the diameter of the medicine powder is 100-180 meshes, vaseline accounting for 10-20% of the weight of the medicine powder is added, and the mixture is uniformly mixed to prepare the paste.
The ointment has strong permeability of lipid matrix, is suitable for deep skin, and can promote inflammation digestion, moisten skin, prevent skin dryness and chap, soften surface covering of skin injury, and remove scale and crust. The ointment can be applied on ulcer surface to protect granulation tissue, promote granulation growth and repair epithelium. And can maintain local temperature, lubricate cuticle of epidermis, facilitate drug permeation, and resist external stimulation.
The medicine can also be prepared into powder, the raw material medicine is smashed into powder, the particle diameter of the medicine powder is 100-180 meshes, the powder can be directly sprinkled on the wound surface of an affected part for the skin injury surface of the seepage, and a layer of gauze is covered on the powder for protection. Aiming at the wound surface with less water seepage, the medicinal powder is uniformly mixed with sesame oil and applied to the affected part, and a layer of gauze is covered on the affected part for protection. The dressing change is carried out every 24 hours.
Clinical cases:
1. for the rest, male, age 70, living in east aster subdistrict of small east Men street in Taiyuan city, itching of shank, split heel, red and swollen skin, accompanied by pain and itching, were found in 2016 (8 months), and were initially diagnosed as impetigo, and were ineffective after two months of medication and injection. Psoriasis is diagnosed by another doctor, and the disease condition is aggravated after the treatment of the psoriasis for more than a month. The medicine is applied in wet dressing in 2017 in 3 months, oral administration is omitted in the whole process, the effect is remarkable in treating for two months, skin cracks heal, pain and itching feel disappear, and the disease symptoms are greatly improved.
2. Liu Zhi, female, aged 39 years old, aged of Taiyuan university, a little psoriasis appears after delivery in 2010, the later psoriasis gradually becomes serious, the medicine taking treatment is not good for many years, the damage to liver and kidney is serious, the doctor visits the office in 2017, the medicine wet compress and the paste application are combined for application, and the patient can be healed after half a year.
3. Guo is a certain disease, a woman is in the age of 50, lives up to the south, and is psoriasis, the patient gets ill about 15 years old, the disease is puzzled for more than thirty years, the patient stays too many times in a hospital during the period, takes various traditional Chinese medicines and western medicines, the disease condition is repeated, the patient is very painful, the treatment starts in the middle ten days of 2016 9 months, the treatment by using the medicine can be obviously improved in one week, the treatment is basically cured after two continuous months, and the treatment is consolidated for one year.
4. Guo in a certain age, female, 18 years old, Dajing yucun, solar dermatitis and seborrheic dermatitis appeared after going out for a resident in 2016, 2017 you see a doctor in 28 days in 4 and 28 months, the ointment is applied, the pruritus is relieved in the evening in the same day, and the patient basically recovers after insisting on using the medicine for half a month.
5. For a certain woman, 26 years old, live in virtuous north street, neurodermatitis, eczema, post-natal foot itching in 2014 summer, the treatment in the alternating period is ineffective, the post-disease condition develops to the back and the four limbs, the injection, the electric baking and the medicine taking are not improved for many years, the doctor can see the doctor in 3 months in 2018, the medicine is externally applied, and the medicine is obviously improved for two more months.
6. Dingdingji, male, 34 years old, Taiyuan Doucheng village, neurodermatitis, itching and cracking of back in 2009, multi-aspect treatment, and repeated and indefinite effects. The medicine is applied and cleaned by wet application in 2018 for 10 months, the skin becomes soft, the cracks heal, and the skin is basically healed.
7. Ma Chi, woman, 28 years old, home Taiyuan city Fuli city, chronic dermatitis, symmetric red spots appear on the whole body in 2019 in 4 months, pruritus is accompanied, the chronic dermatitis is diagnosed in the place of the woman in the last ten days of 4 months, seven doses of the traditional Chinese medicine are taken for external application, the internal medicine is not used, the treatment is obviously improved, and the disease is cured in two months.
The present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims (7)

1. The medicine for treating neurodermatitis and eczema is characterized by comprising the following components in parts by weight:
20-40 parts of paniculate swallowwort root, 10-20 parts of radix euphorbiae lantu, 10-20 parts of common andrographis herb, 15-25 parts of angelica sinensis, 20-40 parts of silkworm excrement, 20-40 parts of Chinese forgetmenot root, 20-40 parts of caulis piperis, 15-25 parts of suberect spatholobus stem, 5-15 parts of cicada slough, 15-25 parts of great burdock achene, 15-25 parts of fineleaf schizonepeta herb, 15-25 parts of divaricate saposhnikovia root, 5-15 parts of realgar, 10-20 parts of alum, 10-20 parts of cortex lycii radicis, 10-20 parts of radix angelicae pubescentis, 10-20 parts of ephedra, 15-25 parts of mint, 15-25 parts of pomegranate bark, 15-25 parts of lightyellow sophora root, 10-20 parts of dittany bark.
2. The medicament for treating neurodermatitis and eczema as claimed in claim 1, which is characterized by comprising the following components in parts by weight:
25-35 parts of paniculate swallowwort root, 12-18 parts of radix euphorbiae lantu, 12-18 parts of common andrographis herb, 18-22 parts of angelica tail, 25-35 parts of silkworm excrement, 25-35 parts of Chinese forgetmenot root, 25-35 parts of glaucescent fissistigma root, 18-22 parts of suberect spatholobus stem, 8-12 parts of cicada slough, 15-22 parts of great burdock achene, 18-22 parts of fineleaf schizonepeta herb, 18-22 parts of divaricate saposhnikovia root, 8-12 parts of realgar, 12-17 parts of alum, 12-17 parts of cortex lycii radicis, 12-17 parts of radix angelicae pubescentis, 12-17 parts of ephedra herb, 18-22 parts of mint, 18-22 parts of pomegranate bark, 18-22 parts of lightyellow sophora root, 12-17.
3. The method for preparing a medicament for treating neurodermatitis and eczema according to claim 1 or 2, wherein the preparation of the liquid medicament comprises the following steps:
1) weighing the traditional Chinese medicinal materials of paniculate swallowwort root, radix euphorbiae lantu, common andrographis herb, angelica tail, silkworm excrement, sambucus chinensis, glaucescent fissistigma root, suberect spatholobus stem, cicada slough, great burdock achene, fineleaf schizonepeta herb, divaricate saposhnikovia root, realgar, alum, cortex lycii radicis, radix angelicae pubescentis, ephedra, mint, pomegranate bark, lightyellow sophora root, cortex dictamni, chaulmoogra seed and pseudolarix, cleaning, mashing the chaulmoogra seed, mixing the medicines, adding 5-8 times of water, soaking for 0.5-1 hour, heating and decocting;
2) repeating the decocting process of step 1) for 2-4 times, wherein the amount of water added each time is 5-8 times of that of the raw material medicinal materials, and mixing the decoctions obtained by multiple times of decocting.
4. The method of using a medicament for the treatment of neurodermatitis and eczema prepared by the method of claim 3, comprising the steps of:
1) cooling the medicinal liquid to 15-20 deg.C to obtain cooled medicinal liquid;
2) preparing multiple layers of gauze according to the size and shape of skin lesion of the affected part, soaking in the medicinal liquid, dipping in the cooled medicinal liquid, and wet-compressing on the affected part, changing the gauze every 3-5 minutes, dipping in the medicinal liquid for each time, wet-compressing for 20-30 minutes for each time, and treating for 1-2 times per day.
5. The use method of a medicine for treating neurodermatitis and eczema as claimed in claim 4, wherein the gauze dipped with the liquid medicine during the wet dressing process is used for preventing the liquid medicine from dripping.
6. The method for preparing a medicament for treating neurodermatitis and eczema according to claim 1 or 2, which comprises the following steps:
1) weighing the traditional Chinese medicinal materials of cynanchum paniculatum, radix euphorbiae lantu, common andrographis herb, angelica tail, silkworm excrement, sambucus chinensis, glaucescent fissistigma root, suberect spatholobus stem, cicada slough, great burdock achene, schizonepeta, divaricate saposhnikovia root, realgar, alum, cortex lycii radicis, radix angelicae pubescentis, ephedra, mint, pomegranate bark, lightyellow sophora root, cortex dictamni, chaulmoogra seed and pseudolarix, cleaning, mixing, crushing into 50-100 meshes of fine powder, adding 5-8 times of ethanol solution, soaking for 7-15 days;
2) repeating the extraction process of step 1) for 2-4 times, wherein the amount of ethanol added each time is 2-3 times of that of the raw materials, and mixing the medicinal liquids obtained by multiple extractions to obtain tincture.
7. The method for preparing a medicine for treating neurodermatitis and eczema according to claim 6, wherein the ethanol solution is ethanol with a concentration of more than 75%.
CN202010136251.8A 2020-03-02 2020-03-02 Medicine for treating neurodermatitis and eczema and preparation method thereof Pending CN111084833A (en)

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