CN111053248A - Earthworm protein oral liquid and preparation method thereof - Google Patents
Earthworm protein oral liquid and preparation method thereof Download PDFInfo
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- CN111053248A CN111053248A CN201811203995.6A CN201811203995A CN111053248A CN 111053248 A CN111053248 A CN 111053248A CN 201811203995 A CN201811203995 A CN 201811203995A CN 111053248 A CN111053248 A CN 111053248A
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Life Sciences & Earth Sciences (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention discloses an earthworm protein oral liquid which is prepared from earthworm protein powder, blueberry anthocyanin, marigold lutein and a flavoring agent, wherein the flavoring agent comprises honey, ethanol, benzoic acid and purified water. In addition, the invention also discloses a preparation method of the earthworm protein oral liquid. Compared with the prior art, the invention discloses and provides a earthworm protein oral liquid which has the effects of improving blood circulation, clearing and activating the channels and collaterals, promoting the regeneration of vascular cells, preventing diseases, eliminating harmful free radicals and the like, and the oral liquid has the advantages of simple preparation method, good taste, safety, no side effect and suitability for long-term administration.
Description
Technical Field
The invention relates to the technical field of health-care product manufacturing, in particular to a earthworm protein oral liquid and a preparation method thereof.
Background
In recent years, with the emphasis on health and safety of food and drink, a great number of health care products are coming out of the market. However, although various products related to different forms of food, medicine and the like have various efficacies, most of the products have substances such as hormones, antibiotics and the like, and the substances can cause dependence and other side effects on human bodies in the using process.
The Lumbricus protein is extracted from Lumbricus, is a macromolecular complex enzyme, and contains multiple active components, such as collagenase, plasmin, lumbrokinase, nucleic acid, and trace elements. The earthworm protein has high nutritive value and also has many health functions, and its pharmacological action relates to several systems of human body, and can raise disease resistance of human body and raise health level of human body.
At present, a plurality of health care products which take earthworm protein as a raw material appear on the market, but in order to pursue diversity of effects, the raw materials of the health care products are various, the preparation method is very complex, and the health care products can not realize complete and full utilization of the components in the utilization of the raw materials, so that excessive waste of the raw material resources is easily caused.
Therefore, the development of an oral earthworm protein solution with high raw material utilization rate, simple preparation process and outstanding efficacy and a preparation method thereof are problems to be solved by the technical personnel in the field.
Disclosure of Invention
In view of the above, the invention provides a earthworm protein oral liquid and a preparation method thereof.
In order to achieve the purpose, the invention adopts the following technical scheme:
an oral liquid of Gelong protein is prepared from Lumbricus protein powder, blueberry anthocyanins, marigold xanthophyll and correctant, wherein the correctant comprises Mel, ethanol, benzoic acid and purified water.
Preferably, the earthworm protein powder, the blueberry anthocyanin, the marigold lutein and the flavoring agent comprise the following components in parts by mass: 80-120 parts of earthworm protein powder, 1-5 parts of blueberry anthocyanin, 1-5 parts of marigold lutein, 20-40 parts of honey, 0.5-2 parts of ethanol, 0.5-2 parts of benzoic acid and 1000-1400 parts of purified water.
Further, on the basis of the technical scheme, the invention can be further improved as follows:
preferably, the earthworm protein powder, the blueberry anthocyanin, the marigold lutein and the flavoring agent comprise the following components in parts by mass: 100-120 parts of earthworm protein powder, 2-4 parts of blueberry anthocyanin, 2-4 parts of marigold lutein, 20-30 parts of honey, 0.5-1 part of ethanol, 0.5-1 part of benzoic acid and 1000-1200 parts of purified water.
Preferably, the earthworm protein powder, the blueberry anthocyanin, the marigold lutein and the flavoring agent comprise the following components in parts by mass: 100 parts of earthworm protein powder, 3 parts of blueberry anthocyanin, 3 parts of marigold lutein, 25 parts of honey, 1 part of ethanol, 1 part of benzoic acid and 1200 parts of purified water.
According to the technical scheme, compared with the prior art, the earthworm protein oral liquid is prepared from earthworm protein powder serving as a main raw material, wherein the earthworm protein can dissolve large and small thrombi in a human body, dredge large and small blood vessels and microvessels of the whole body and prevent serious diseases of the human body; the fibrin network on the vessel wall can be dissolved, so that blood dirt attached to the blood can be cleaned, the vessel can be further dredged, and the elasticity of the vessel can be recovered; can regularly remove metabolic waste in blood and blood vessels, and restore the vital function of the systemic sclerosis capillary vessels.
Meanwhile, blueberry anthocyanin and marigold lutein are added into the formula, wherein the blueberry anthocyanin is obtained by unfreezing and juicing frozen blueberry fruits, extracting a concentrated solution from peel residues through absolute ethyl alcohol, adding 1:1 deionized water according to the volume of the concentrated solution to precipitate the concentrated solution, filtering and concentrating an aqueous solution extracting solution of the concentrated solution; the marigold lutein is prepared by granulating marigold before extraction, extracting with organic solvent, desolventizing the extract to obtain yellow oily liquid, and separating and purifying.
Specifically, after the blueberry anthocyanin is added, a protective barrier can be formed by preventing the reaction of peroxide ions, chelating certain specific metal ions in a body, preventing the generation of hydroxyl, inhibiting lipid peroxidation and acting with collagen, so that the tissue is isolated from contacting with external free radicals, and meanwhile, stable semiquinone type free radicals can be generated through the reaction of phenolic hydroxyl and free radical molecules, the chain type reaction of the free radicals is stopped, and the free radicals are reduced and eliminated. The marigold lutein has excellent inoxidizability, can prevent cell aging and organism aging, improve the function of an immune system, prevent cardiovascular sclerosis, coronary heart disease, tumor and other diseases caused by organism aging, simultaneously can prevent muscular degeneration, prevent and treat vision loss and blindness caused by senile eyeball retina macular degeneration, and also has obvious effects of radiation protection, skin protection, moistening and aging resistance. Because the blueberry anthocyanin and marigold lutein are natural antioxidants, the antioxidant capacity of the blueberry anthocyanin and the marigold lutein can be enhanced by compounding the blueberry anthocyanin and the marigold lutein, and the effects of mutual reinforcement and mutual assistance are achieved, so that the effects of respective immunity enhancement, cancer resistance, skin care and the like are enhanced.
In addition, the honey, the ethanol and the benzoic acid are used as the flavoring agent, so that the oral liquid product can be endowed with pleasant feeling in the sense aspect, wherein,
the honey can improve the taste of the oral liquid, and also has glucose and fructose which can be directly absorbed by a human body, and the proportion of the glucose and the fructose in the honey is very proper, so that the honey not only can provide energy and nutrient substances for an organism, but also can provide a carbohydrate which is most suitable for saving protein. In addition, the honey also contains more than 20 mineral substances with the proportion almost equal to the proportion of human serum, various amino acids, including 8 essential amino acids which can not be synthesized by human body, more than 20 vitamins which can promote the growth and metabolism of human body, a plurality of active enzymes and invertase which are necessary for human body, and more than 180 nutrient substances such as trace elements, organic acids, flavonoids and the like, and has extremely strong health care function.
Ethanol is a semi-polar solvent, has solubility performance between polar and non-polar solvents, and can dissolve some water-soluble components and some non-polar components. The ethanol is used in the invention, so that the taste and stability of the oral liquid can be ensured. In addition, the content of ethanol in the invention is low, and adverse effect on human body is avoided.
The benzoic acid is used as a fragrance fixative and a preservative in the invention, and the proportion of the benzoic acid in the total formula is very small, and the benzoic acid does not have adverse effect on human bodies.
The invention also provides a preparation method of the earthworm protein oral liquid, which comprises the following steps:
1) accurately weighing Lumbricus protein powder in 1000ml conical flask, extracting with ethanol solution at 45-55 deg.C for 1-2 hr for 2-3 times in ultrasonic cleaner, mixing extractive solutions, concentrating, and recovering ethanol under reduced pressure;
2) treating the concentrated product with enzyme, purifying, filtering, and concentrating the filtered extractive solution to obtain Lumbricus protein powder concentrated solution;
3) accurately weighing blueberry anthocyanin and marigold lutein, mixing, fully stirring, and adding honey, ethanol, benzoic acid and purified water to obtain a mixed solution;
4) filtering the mixed solution under the conditions that the aperture of a filter membrane is 1-5 mu m and the pressure is 0.2-1 MPa;
5) mixing the above filtrate and Lumbricus protein powder concentrate, adding the rest purified water, fine filtering, diluting to desired volume, packaging, and sterilizing at high temperature to obtain the Lumbricus protein oral liquid.
Among them, the ethanol solution in the step 1) preferably has a mass concentration of 75%.
Preferably, the extracts are combined and concentrated to a density of 1.08 in step 1) above.
Preferably, 120-140 parts of purified water is added as a solvent in the step 1).
Preferably, the amount of the purified water in the step 3) is 150 portions to 100 portions.
Preferably, the temperature for high-temperature sterilization in the step 5) is 100-120 ℃.
By adopting the raw materials and the preparation method, the oral liquid has the effects of improving blood circulation, clearing and activating the channels and collaterals, promoting the regeneration of vascular cells, preventing diseases, eliminating harmful free radicals, softening blood vessels, reducing blood sugar, reducing blood pressure, resisting cancer, resisting ultraviolet rays and oxidation, slowing down aging, maintaining beauty and keeping young, improving sleep, enhancing autoimmunity, protecting eyes, enhancing eyesight, relieving asthenopia, delaying aging of eyes, protecting eyes from light damage, protecting yellow spots in eyes, promoting the development of yellow spots and the like. The oral liquid has the advantages of simple preparation method, short period and low cost, fully utilizes the effective components and effects of the raw materials, has the characteristics of good taste, safety and no side effect, and is suitable for long-term administration.
Detailed Description
The technical solutions of the present invention will be described clearly and completely below, and it should be understood that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The embodiment of the invention discloses a earthworm protein oral liquid which is prepared from earthworm protein powder, blueberry anthocyanin, marigold lutein and a flavoring agent, wherein the flavoring agent comprises honey, ethanol, benzoic acid and purified water.
Example 1:
the earthworm protein oral liquid comprises the following raw materials in parts by weight:
the preparation method of the earthworm protein oral liquid comprises the following steps:
1) accurately weighing Lumbricus protein powder in 1000ml conical flask, extracting with 75% ethanol solution at 45-55 deg.C for 2 times (2 hr each time), adding 120 parts of purified water as solvent, mixing extractive solutions, concentrating to density of 1.08, and recovering ethanol under reduced pressure;
2) treating the concentrated product with enzyme, purifying, filtering, and concentrating the filtered extractive solution to obtain Lumbricus protein powder concentrated solution;
3) accurately weighing blueberry anthocyanin and marigold lutein, mixing, fully stirring, and adding honey, ethanol, benzoic acid and purified water, wherein the using amount of the purified water is 100 parts, so as to obtain a mixed solution;
4) filtering the mixed solution under the conditions that the aperture of a filter membrane is 1-5 mu m and the pressure is 0.2-1 MPa;
5) mixing the above filtrate and Lumbricus protein powder concentrate, adding the rest purified water, fine filtering, diluting to desired volume, packaging, and sterilizing at high temperature of 100 deg.C to obtain Lumbricus protein oral liquid.
Example 2:
the earthworm protein oral liquid comprises the following raw materials in parts by weight:
the preparation method of the earthworm protein oral liquid comprises the following steps:
1) accurately weighing Lumbricus protein powder in 1000ml conical flask, extracting with 75% ethanol solution at 45-55 deg.C for 2 times (2 hr each time), adding 130 parts of purified water as solvent, mixing extractive solutions, concentrating to density of 1.08, and recovering ethanol under reduced pressure;
2) treating the concentrated product with enzyme, purifying, filtering, and concentrating the filtered extractive solution to obtain Lumbricus protein powder concentrated solution;
3) accurately weighing blueberry anthocyanin and marigold lutein, mixing, fully stirring, and adding honey, ethanol, benzoic acid and purified water, wherein the using amount of the purified water is 120 parts, so as to obtain a mixed solution;
4) filtering the mixed solution under the conditions that the aperture of a filter membrane is 1-5 mu m and the pressure is 0.2-1 MPa;
5) mixing the above filtrate and Lumbricus protein powder concentrate, adding the rest purified water, fine filtering, diluting to desired volume, packaging, and sterilizing at 110 deg.C to obtain Lumbricus protein oral liquid.
Example 3:
the earthworm protein oral liquid comprises the following raw materials in parts by weight:
the preparation method of the earthworm protein oral liquid comprises the following steps:
1) accurately weighing Lumbricus protein powder in 1000ml conical flask, extracting with 75% ethanol solution at 45-55 deg.C for 1.5 hr for 3 times, adding 135 parts of purified water as solvent, mixing extractive solutions, concentrating to density of 1.08, and recovering ethanol under reduced pressure;
2) treating the concentrated product with enzyme, purifying, filtering, and concentrating the filtered extractive solution to obtain Lumbricus protein powder concentrated solution;
3) accurately weighing blueberry anthocyanin and marigold lutein, mixing, fully stirring, and adding honey, ethanol, benzoic acid and purified water, wherein the using amount of the purified water is 130 parts, so as to obtain a mixed solution;
4) filtering the mixed solution under the conditions that the aperture of a filter membrane is 1-5 mu m and the pressure is 0.2-1 MPa;
5) mixing the above filtrate and Lumbricus protein powder concentrate, adding the rest purified water, fine filtering, diluting to desired volume, packaging, and sterilizing at 120 deg.C to obtain Lumbricus protein oral liquid.
Example 4:
the earthworm protein oral liquid comprises the following raw materials in parts by weight:
the preparation method of the earthworm protein oral liquid comprises the following steps:
1) accurately weighing Lumbricus protein powder in 1000ml conical flask, extracting with 75% ethanol solution at 45-55 deg.C for 1 hr for 3 times, adding 140 parts of purified water as solvent, mixing extractive solutions, concentrating to density of 1.08, and recovering ethanol under reduced pressure;
2) treating the concentrated product with enzyme, purifying, filtering, and concentrating the filtered extractive solution to obtain Lumbricus protein powder concentrated solution;
3) accurately weighing blueberry anthocyanin and marigold lutein, mixing, fully stirring, and adding honey, ethanol, benzoic acid and purified water, wherein the using amount of the purified water is 150 parts, so as to obtain a mixed solution;
4) filtering the mixed solution under the conditions that the aperture of a filter membrane is 1-5 mu m and the pressure is 0.2-1 MPa;
5) mixing the above filtrate and Lumbricus protein powder concentrate, adding the rest purified water, fine filtering, diluting to desired volume, packaging, and sterilizing at 120 deg.C to obtain Lumbricus protein oral liquid.
Comparative example 1:
the earthworm protein oral liquid comprises the following raw materials in parts by weight:
the preparation method of the earthworm protein oral liquid is the same as that of the example 1.
Comparative example 2:
the earthworm protein oral liquid comprises the following raw materials in parts by weight:
the preparation method of the earthworm protein oral liquid is the same as that of the embodiment 4.
One, the following are stability tests performed on the earthworm protein oral liquid in examples 1 to 4, and the specific product test data results are as follows:
1. the experimental samples were the oral liquid of earthworm protein prepared in examples 1-4 and comparative documents 1-2.
2. Test method
The experimental samples are placed in an incubator (the temperature is 20-25 ℃, and the relative humidity is 50% -60%) to be stored for 24 months, and the characters and the microbial limits of the experimental samples are detected in 3 rd, 6 th, 12 th, 15 th, 20 th and 24 th months respectively.
①, its characteristics are red brown clear liquid, slightly fragrant smell, sweet taste and slightly bitter taste.
② microbial Limit
The examination was carried out according to the Escherichia coli examination method in the appendix of the first edition of Chinese pharmacopoeia (2005 edition).
TABLE 1
It can be seen from table 1 that the earthworm protein oral liquid prepared in examples 1-4 of the present invention has no change in appearance after being stored for 24 months in an environment with a temperature of 20-25 ℃ and a relative humidity of 50-60%, and the microbial limit also meets the requirements of relevant regulations, while comparative example 1 and comparative example 2 have a deterioration condition within 15 months in the same storage environment, thereby proving that the earthworm protein oral liquid prepared in the present invention has higher stability and longer shelf life.
Second, the following is a related experiment performed on the hyperlipemia mouse by using the inventive earthworm protein oral liquid.
And (3) perfusing a high-fat emulsion into a white mouse to form a white mouse hyperlipidemia model, continuously administering different doses of earthworm protein oral liquid for 3 months, and observing the influence of the earthworm protein oral liquid on TC, TG, LDL-C, HDL-C, SOD, MDA levels and mouse weight of the white mouse with hyperlipidemia.
As a result: the large and small dosage of earthworm protein oral liquid can improve the SOD activity of the hyperlipoidemia mice, reduce the MDA content, reduce the weight of the hyperlipoidemia mice, obviously reduce the content of blood fat (TC, TG and LDL-C) and increase the HDL-C.
And (4) conclusion: the Lumbricus protein oral liquid has effect in regulating lipid disorder of hyperlipemia mouse.
Thirdly, the practical application cases and the action effects of the formula in clinic are as follows:
case 1: yellow lady in Haizu district, Beijing, 62 years old has a decade of hypertension accompanied by insomnia. The oral liquid starts to be taken in 2017 and 10 months, one month is a treatment course, after one treatment course, the insomnia symptom is obviously relieved, the blood pressure is obviously fallen back, after three treatment courses of continuous taking, the insomnia symptom disappears, the blood pressure is normal, and the mental condition is obviously improved.
Case 2: mr. in Xuhui district of Shanghai, age 27, common cold is recurrent, weak and intolerant of cold. The oral liquid is taken in 8 months in 2017, one month is a treatment course, the symptoms are obviously relieved after one treatment course, and the symptoms disappear and do not relapse after the oral liquid is continuously taken for one treatment course.
Case 3: for women in the Jianghhan area of Hubei Wuhan, age 41, the mood is restless and anxiety. The oral liquid is taken in 12 months in 2017, one month is a treatment course, symptoms are cured after one treatment course, and the symptoms do not relapse after the oral liquid is continuously taken to regulate the body.
Case 4: lu women in Xuhui district of Shanghai city, age 33, blurred vision, dry eyes, pressure and burning sensation, photophobia, diplopia and lacrimation. The oral liquid is taken in 2017 and 10 months, one month is a treatment course, the symptoms related to asthenopia are obviously relieved after one treatment course, the vision is recovered to be normal after the oral liquid is continuously taken for three treatment courses, and the asthenopia does not relapse after the oral liquid is continuously taken for regulating the body.
The embodiments in the present description are described in a progressive manner, each embodiment focuses on differences from other embodiments, and the same and similar parts among the embodiments are referred to each other.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.
Claims (10)
1. The earthworm protein oral liquid is characterized by being prepared from earthworm protein powder, blueberry anthocyanin, marigold lutein and a flavoring agent, wherein the flavoring agent comprises honey, ethanol, benzoic acid and purified water.
2. The earthworm protein oral liquid according to claim 1, wherein: the earthworm protein powder, the blueberry anthocyanin, the marigold lutein and the flavoring agent comprise the following components in parts by weight: 80-120 parts of earthworm protein powder, 1-5 parts of blueberry anthocyanin, 1-5 parts of marigold lutein, 20-40 parts of honey, 0.5-2 parts of ethanol, 0.5-2 parts of benzoic acid and 1000-1400 parts of purified water.
3. The earthworm protein oral liquid according to claim 1, wherein: the earthworm protein powder, the blueberry anthocyanin, the marigold lutein and the flavoring agent comprise the following components in parts by weight: 100-120 parts of earthworm protein powder, 2-4 parts of blueberry anthocyanin, 2-4 parts of marigold lutein, 20-30 parts of honey, 0.5-1 part of ethanol, 0.5-1 part of benzoic acid and 1000-1200 parts of purified water.
4. The earthworm protein oral liquid according to claim 1, wherein: the earthworm protein powder, the blueberry anthocyanin, the marigold lutein and the flavoring agent comprise the following components in parts by weight: 100 parts of earthworm protein powder, 3 parts of blueberry anthocyanin, 3 parts of marigold lutein, 25 parts of honey, 1 part of ethanol, 1 part of benzoic acid and 1200 parts of purified water.
5. A preparation method of earthworm protein oral liquid is characterized in that: the method comprises the following steps:
1) accurately weighing Lumbricus protein powder in 1000ml conical flask, extracting with ethanol solution at 45-55 deg.C for 1-2 hr for 2-3 times in ultrasonic cleaner, mixing extractive solutions, concentrating, and recovering ethanol under reduced pressure;
2) treating the concentrated product with enzyme, purifying, filtering, and concentrating the filtered extractive solution to obtain Lumbricus protein powder concentrated solution;
3) accurately weighing blueberry anthocyanin and marigold lutein, mixing, fully stirring, and adding honey, ethanol, benzoic acid and purified water to obtain a mixed solution;
4) filtering the mixed solution under the conditions that the aperture of a filter membrane is 1-5 mu m and the pressure is 0.2-1 MPa;
5) mixing the above filtrate and Lumbricus protein powder concentrate, adding the rest purified water, fine filtering, diluting to desired volume, packaging, and sterilizing at high temperature to obtain the Lumbricus protein oral liquid.
6. The preparation method of a earthworm protein oral liquid according to claim 1, which is characterized in that: the mass concentration of the ethanol solution in the step 1) is 75 percent.
7. The preparation method of a earthworm protein oral liquid according to claim 1, which is characterized in that: in step 1), the extracts were combined and concentrated to a density of 1.08.
8. The preparation method of a earthworm protein oral liquid according to claim 1, which is characterized in that: in the step 1), 120-140 parts of purified water is added as a solvent.
9. The preparation method of a earthworm protein oral liquid according to claim 1, which is characterized in that: the amount of the purified water in the step 3) is 100-150 parts.
10. The preparation method of a earthworm protein oral liquid according to claim 1, which is characterized in that: the temperature for high-temperature sterilization in the step 5) is 100-120 ℃.
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Application publication date: 20200424 |