CN111032025A - Suv39h1组蛋白甲基转移酶的抑制剂在癌症联合治疗中的用途 - Google Patents

Suv39h1组蛋白甲基转移酶的抑制剂在癌症联合治疗中的用途 Download PDF

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Publication number
CN111032025A
CN111032025A CN201880054127.8A CN201880054127A CN111032025A CN 111032025 A CN111032025 A CN 111032025A CN 201880054127 A CN201880054127 A CN 201880054127A CN 111032025 A CN111032025 A CN 111032025A
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inhibitor
immune checkpoint
histone methyltransferase
suv39h1
cells
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Chinese (zh)
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S·阿米格瑞纳
E·皮亚乔
L·尼布尔斯基
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Institut National de la Sante et de la Recherche Medicale INSERM
Institut Curie
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Institut National de la Sante et de la Recherche Medicale INSERM
Institut Curie
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
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    • C12N9/10—Transferases (2.)
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    • C12N9/1007—Methyltransferases (general) (2.1.1.)

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CN201880054127.8A 2017-06-20 2018-06-20 Suv39h1组蛋白甲基转移酶的抑制剂在癌症联合治疗中的用途 Pending CN111032025A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17305755.5 2017-06-20
EP17305755 2017-06-20
PCT/EP2018/066383 WO2018234367A1 (en) 2017-06-20 2018-06-20 SUV39H1 HISTONE METHYLTRANSFERASE INHIBITOR FOR USE IN ANTICANCER POLYTHERAPY

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CN111032025A true CN111032025A (zh) 2020-04-17

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US (3) US20200147099A1 (enExample)
EP (1) EP3641739A1 (enExample)
JP (2) JP2020524157A (enExample)
CN (1) CN111032025A (enExample)
WO (1) WO2018234367A1 (enExample)

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US20200147099A1 (en) 2020-05-14
EP3641739A1 (en) 2020-04-29
JP2020524157A (ja) 2020-08-13
WO2018234367A1 (en) 2018-12-27
JP2023162213A (ja) 2023-11-08
US20240216388A1 (en) 2024-07-04
US20200157225A1 (en) 2020-05-21

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