MX2022016544A - Agentes de union a lair-1 y metodos para su uso. - Google Patents
Agentes de union a lair-1 y metodos para su uso.Info
- Publication number
- MX2022016544A MX2022016544A MX2022016544A MX2022016544A MX2022016544A MX 2022016544 A MX2022016544 A MX 2022016544A MX 2022016544 A MX2022016544 A MX 2022016544A MX 2022016544 A MX2022016544 A MX 2022016544A MX 2022016544 A MX2022016544 A MX 2022016544A
- Authority
- MX
- Mexico
- Prior art keywords
- binding agents
- lair
- methods
- antibodies
- compositions
- Prior art date
Links
- 239000011230 binding agent Substances 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 2
- 101001138062 Homo sapiens Leukocyte-associated immunoglobulin-like receptor 1 Proteins 0.000 abstract 1
- 102100020943 Leukocyte-associated immunoglobulin-like receptor 1 Human genes 0.000 abstract 1
- 108010025001 leukocyte-associated immunoglobulin-like receptor 1 Proteins 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/74—Inducing cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
La presente descripción proporciona agentes de unión, tales como anticuerpos, que se unen específicamente a LAIR-1, incluido LAIR-1 humano, así como composiciones que comprenden los agentes de unión, y métodos para su uso. La descripción también proporciona polinucleótidos y vectores relacionados que codifican los agentes de unión y las células que comprenden los agentes de unión.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202063042299P | 2020-06-22 | 2020-06-22 | |
US202063122877P | 2020-12-08 | 2020-12-08 | |
PCT/US2021/038251 WO2021262597A2 (en) | 2020-06-22 | 2021-06-21 | Lair-1-binding agents and methods of use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2022016544A true MX2022016544A (es) | 2023-04-05 |
Family
ID=76959074
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2022016544A MX2022016544A (es) | 2020-06-22 | 2021-06-21 | Agentes de union a lair-1 y metodos para su uso. |
Country Status (15)
Country | Link |
---|---|
US (1) | US20220041711A1 (es) |
EP (1) | EP4168451A2 (es) |
JP (1) | JP2023532857A (es) |
KR (1) | KR20230039640A (es) |
CN (2) | CN116813777A (es) |
AU (1) | AU2021296168A1 (es) |
BR (1) | BR112022026284A2 (es) |
CA (1) | CA3187944A1 (es) |
CL (1) | CL2022003684A1 (es) |
CO (1) | CO2022018537A2 (es) |
IL (1) | IL299245A (es) |
MX (1) | MX2022016544A (es) |
PE (1) | PE20230839A1 (es) |
TW (1) | TW202216768A (es) |
WO (1) | WO2021262597A2 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20230220076A1 (en) * | 2021-12-21 | 2023-07-13 | Ngm Biopharmaceuticals, Inc. | Combinational use of an anti-ilt3 antibody and an anti-lair-1 antibody |
WO2023173091A1 (en) * | 2022-03-11 | 2023-09-14 | Ngm Biopharmaceuticals, Inc. | Osteoclast-associated ig-like receptor (oscar) and methods of use thereof |
WO2023215829A1 (en) * | 2022-05-05 | 2023-11-09 | Amgen Inc. | Heteromultimer binding dll3 and cd3 |
WO2024067864A1 (en) * | 2022-09-30 | 2024-04-04 | Shanghai Junshi Biosciences Co., Ltd. | Anti-lair1 antibodies and their uses |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2004850A2 (en) * | 2006-03-08 | 2008-12-24 | Universitair Medisch Centrum Utrecht | Interfering in activation of an immune cell by influencing interaction of lair and collagen. |
KR101947702B1 (ko) | 2012-10-04 | 2019-02-14 | 다나-파버 캔서 인스티튜트 인크. | 인간 단클론 항-pd-l1 항체 및 사용 방법 |
DK2992017T3 (da) | 2013-05-02 | 2021-01-25 | Anaptysbio Inc | Antistoffer rettet mod programmeret død-1 (pd-1) |
RS63446B1 (sr) * | 2016-06-30 | 2022-08-31 | Prothena Biosciences Ltd | Kompozicije za lečenje amiloidoze |
KR102617853B1 (ko) * | 2017-01-02 | 2023-12-27 | 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 | 항-lair1 항체 및 그의 용도 |
-
2021
- 2021-06-21 IL IL299245A patent/IL299245A/en unknown
- 2021-06-21 JP JP2022579047A patent/JP2023532857A/ja active Pending
- 2021-06-21 KR KR1020237000749A patent/KR20230039640A/ko unknown
- 2021-06-21 CA CA3187944A patent/CA3187944A1/en active Pending
- 2021-06-21 CN CN202310748928.7A patent/CN116813777A/zh active Pending
- 2021-06-21 BR BR112022026284A patent/BR112022026284A2/pt unknown
- 2021-06-21 TW TW110122557A patent/TW202216768A/zh unknown
- 2021-06-21 US US17/353,295 patent/US20220041711A1/en active Pending
- 2021-06-21 MX MX2022016544A patent/MX2022016544A/es unknown
- 2021-06-21 EP EP21742964.6A patent/EP4168451A2/en active Pending
- 2021-06-21 AU AU2021296168A patent/AU2021296168A1/en active Pending
- 2021-06-21 CN CN202180050298.5A patent/CN116209676A/zh active Pending
- 2021-06-21 WO PCT/US2021/038251 patent/WO2021262597A2/en unknown
- 2021-06-21 PE PE2022002982A patent/PE20230839A1/es unknown
-
2022
- 2022-12-21 CL CL2022003684A patent/CL2022003684A1/es unknown
- 2022-12-21 CO CONC2022/0018537A patent/CO2022018537A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
EP4168451A2 (en) | 2023-04-26 |
PE20230839A1 (es) | 2023-05-19 |
KR20230039640A (ko) | 2023-03-21 |
CN116813777A (zh) | 2023-09-29 |
TW202216768A (zh) | 2022-05-01 |
BR112022026284A2 (pt) | 2023-03-07 |
WO2021262597A9 (en) | 2022-06-02 |
WO2021262597A3 (en) | 2022-02-24 |
IL299245A (en) | 2023-02-01 |
AU2021296168A1 (en) | 2023-02-02 |
CN116209676A (zh) | 2023-06-02 |
JP2023532857A (ja) | 2023-08-01 |
CA3187944A1 (en) | 2021-12-30 |
CL2022003684A1 (es) | 2023-07-28 |
US20220041711A1 (en) | 2022-02-10 |
CO2022018537A2 (es) | 2023-03-07 |
WO2021262597A2 (en) | 2021-12-30 |
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