CN111000943A - Antidiarrheal composition for treating intestinal digestive diseases and preparation method thereof - Google Patents

Antidiarrheal composition for treating intestinal digestive diseases and preparation method thereof Download PDF

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Publication number
CN111000943A
CN111000943A CN201911419219.4A CN201911419219A CN111000943A CN 111000943 A CN111000943 A CN 111000943A CN 201911419219 A CN201911419219 A CN 201911419219A CN 111000943 A CN111000943 A CN 111000943A
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leaves
antidiarrheal composition
dendrobium
antidiarrheal
stir
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高加喜
高超湖
高超栖
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • A61K36/8984Dendrobium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals

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  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
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  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses an antidiarrheal composition for treating intestinal tract digestive diseases and a preparation method thereof, wherein the antidiarrheal composition comprises 30-35g of dendrobium leaves, 100ml of water and 400ml of compound gentamicin oral liquid one; the preparation method comprises the following steps: deactivating enzymes of the picked dendrobium leaves, stir-frying, soaking the stir-fried dendrobium leaves in boiled water, adding one compound gentamycin oral liquid, and uniformly stirring to obtain the antidiarrheal composition. Proved by verification, the antidiarrheal composition can achieve the aim of quickly stopping diarrhea, has obvious treatment effect, is suitable for patients with diarrhea, can help the patients with diarrhea to get rid of pain, and achieves the effect of quickly treating both principal and secondary aspects of diseases.

Description

Antidiarrheal composition for treating intestinal digestive diseases and preparation method thereof
Technical Field
The invention relates to the field of biological medicines, and in particular relates to an antidiarrheal composition for treating intestinal digestive diseases and a preparation method thereof.
Background
Diarrhea is a common symptom, and is divided into infectious and non-infectious types according to etiology, and is a clinical syndrome mainly including diarrhea caused by multiple pathogens and multiple factors. Diarrhea is one of the symptoms which people inevitably encounter in life, and when people eat rotten and deteriorated unclean food, the diarrhea is also caused by bacterial infection, and the chronic diarrhea is a very painful thing. In the prior art, various medicines for treating diarrhea, such as fukening, berberine, phosphorus acid and the like, are used for treating diarrhea, but most of the medicines are required to be taken for a plurality of times to be stopped, but the curative effect is not exact enough, the symptoms and root causes cannot be treated, and more importantly, the medicines have large side effects. The existing method for treating diarrhea mainly comprises the steps of adding some anti-inflammatory drugs into an infusion supplement body for symptomatic treatment, taking western medicines as main medicines, and being long in treatment time, inconvenient to take, high in cost and inconvenient for families, wherein the western medicines have certain side effects and need hospitalization on patients with unobvious effects.
Therefore, the development of a safe and effective medicine for helping the diarrhea patients get rid of the pain and achieving the effect of rapidly treating both principal and secondary aspect of disease is urgently needed.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provides a quick and efficient antidiarrheal composition for treating intestinal digestive diseases and a preparation method thereof.
In order to achieve the purpose, the invention adopts the following technical scheme:
an antidiarrheal composition for treating digestive disorders of the intestinal tract, which comprises the following components:
30-35g of dendrobium leaves;
100ml of water;
one oral compound gentamicin liquid.
The compound gentamicin oral liquid is produced by Shandong mainland pharmaceutical industry Co Ltd, and is in the Chinese medicine standard H10950228.
The herba Dendrobii leaf is herba Dendrobii leaf.
The dendrobium leaves are dendrobium officinale leaves grafted on eucommia ulmoides trees.
The invention also provides a preparation method of the antidiarrheal composition for treating intestinal digestive diseases, which comprises the following steps:
1) preparing dendrobium leaves: picking fresh dendrobe leaves, cutting the dendrobe leaves into strips with the thickness of 3-4mm after airing, then carrying out enzyme deactivation treatment, putting the dendrobe leaves subjected to enzyme deactivation treatment into a frying pan, stir-frying at the stir-frying temperature of 45-55 ℃ for 30-40min, then stopping heating, and continuously stir-frying until the temperature of the frying pan is reduced to room temperature;
2) taking 30-35g of stir-fried dendrobe leaves, and soaking in 100-400ml of boiled water to obtain dendrobe leaf tea;
3) and adding one compound gentamicin oral liquid into the dendrobium leaf tea, and uniformly stirring to obtain the antidiarrheal composition.
Further, the deactivation of enzymes of the dendrobium leaves is as follows: continuously parching herba Dendrobii leaf in pan of de-enzyming machine at 65-75 deg.C for 30-40 min.
The taking method of the antidiarrheal composition for treating the intestinal tract digestive diseases comprises the following steps: the antidiarrheal composition is orally taken 1-2 times a day, and each time of the antidiarrheal composition contains 30-35g of dendrobium leaves.
By adopting the technical scheme, the dendrobium leaf raw material is added with water to be brewed into tea, and then one compound gentamicin is added, so that the antidiarrheal effect is obvious. The antidiarrheal composition only comprises the dendrobium leaves and the gentamicin, is simple and convenient to prepare, has wide medicine sources, utilizes the respective effects of the raw material components, is matched with each other to effectively treat patients with diarrhea, can achieve the aim of quickly relieving diarrhea through verification, has obvious treatment effect, and is suitable for the patients with diarrhea. The raw materials of the invention are cheap and easily available, the preparation method is simple and easy, the cost is low, the use is convenient, the invention is suitable for popularization and application, and the invention can help the diarrhea patients to get rid of the pain and achieve the effect of quickly treating both principal and secondary aspects of diseases.
Detailed Description
An antidiarrheal composition for treating digestive disorders of the intestinal tract, which comprises the following components:
30-35g of dendrobium leaves;
100ml of water;
one oral compound gentamicin liquid.
The compound gentamicin oral liquid is produced by Shandong mainland pharmaceutical industry Co Ltd, and is in the Chinese medicine standard H10950228.
The dendrobium leaves are dendrobium officinale leaves grafted on eucommia ulmoides trees.
The preparation method of the antidiarrheal composition for treating the intestinal digestive diseases comprises the following steps:
1) preparing dendrobium leaves: picking fresh dendrobe leaves, cutting the dendrobe leaves into strips with the thickness of 3-4mm after airing, then continuously stir-frying the dendrobe leaves in a pan of a de-enzyming machine at the temperature of 65-75 ℃ for 30-40min, and finishing de-enzyming treatment; then putting the leaves of the dendrobium subjected to deactivation of enzymes into a frying pan to continuously stir-fry, wherein the stir-frying temperature is 45-55 ℃, the stir-frying is carried out for 30-40min, then, the heating is stopped, and the stir-frying is continuously carried out until the temperature of the frying pan is reduced to the room temperature;
2) taking 30-35g of stir-fried dendrobe leaves, and soaking in 100-400ml of boiled water to obtain dendrobe leaf tea;
3) and adding one compound gentamicin oral liquid into the dendrobium leaf tea, and uniformly stirring to obtain the antidiarrheal composition.
The antidiarrheal composition is taken as follows: the antidiarrheal composition is orally taken 1-2 times a day, and each time of the antidiarrheal composition contains 30-35g of dendrobium leaves.
Example 1
An antidiarrheal composition for treating digestive disorders of the intestinal tract, which comprises the following components:
30g of dendrobium leaves;
200ml of water;
one oral compound gentamicin liquid.
The preparation method of the antidiarrheal composition for treating the intestinal digestive diseases comprises the following steps:
1) preparing dendrobium leaves: picking fresh dendrobium officinale leaves grafted on eucommia ulmoides trees, cutting the dendrobium officinale leaves into strips of 3.5mm after airing, then continuously stir-frying the dendrobium officinale leaves in a pan of a water-removing machine, wherein the pan temperature is 70 ℃, and the stir-frying time is 35min, and completing the water-removing treatment; then putting the leaves of the dendrobium subjected to the enzyme deactivation treatment into a frying pan to continuously stir and fry, wherein the stir-frying temperature is 50 ℃, the stir-frying time is 35min, then stopping heating, and continuously stir-frying until the temperature of the frying pan is reduced to the room temperature;
2) taking 30g of stir-fried dendrobe leaves, and soaking in 200ml of boiled water to obtain dendrobe leaf tea;
3) adding one compound gentamycin oral liquid (national standard H10950228) produced by Shandong mainland pharmaceutical industry Co., Ltd.) into the dendrobe leaf tea, and stirring to obtain the antidiarrheal composition.
The antidiarrheal composition is taken as follows: the antidiarrheal composition is orally taken 1-2 times a day, and each time of the antidiarrheal composition contains 30g of dendrobium leaves.
Example 2
An antidiarrheal composition for treating digestive disorders of the intestinal tract, which comprises the following components:
35g of dendrobium leaves;
400ml of water;
one oral compound gentamicin liquid.
The preparation method of the antidiarrheal composition for treating the intestinal digestive diseases comprises the following steps:
1) preparing dendrobium leaves: picking fresh dendrobium officinale leaves grafted on eucommia ulmoides trees, cutting the dendrobium officinale leaves into strips with the length of 3mm after airing, then continuously stir-frying the dendrobium officinale leaves in a pan of a water-removing machine, wherein the pan temperature is 65 ℃, and the stir-frying time is 40min, so that the water-removing treatment is completed; then putting the leaves of the dendrobium subjected to the enzyme deactivation treatment into a frying pan to continuously stir and fry, wherein the stir-frying temperature is 45 ℃, stir-frying for 40min, then stopping heating, and continuously stir-frying until the temperature of the frying pan is reduced to the room temperature;
2) taking 35g of stir-fried dendrobe leaves, and soaking in 400ml of boiled water to obtain dendrobe leaf tea;
3) adding one compound gentamycin oral liquid (national standard H10950228) produced by Shandong mainland pharmaceutical industry Co., Ltd.) into the dendrobe leaf tea, and stirring to obtain the antidiarrheal composition.
The antidiarrheal composition is taken as follows: the antidiarrheal composition is orally taken 1-2 times a day, and each time of oral antidiarrheal composition contains 35g of dendrobium leaves.
Example 3
An antidiarrheal composition for treating digestive disorders of the intestinal tract, which comprises the following components:
30g of dendrobium leaves;
100ml of water;
one oral compound gentamicin liquid.
The preparation method of the antidiarrheal composition for treating the intestinal digestive diseases comprises the following steps:
1) preparing dendrobium leaves: picking fresh dendrobium officinale leaves grafted on eucommia ulmoides trees, cutting the dendrobium officinale leaves into strips of 4mm after airing, then continuously stir-frying the dendrobium officinale leaves in a pan of a water-removing machine, wherein the pan temperature is 75 ℃, and the stir-frying time is 30min, so that the water-removing treatment is completed; then putting the leaves of the dendrobium subjected to the enzyme deactivation treatment into a frying pan to continuously stir and fry the leaves of the dendrobium in the frying pan, wherein the stir-frying temperature is 55 ℃, the stir-frying time is 30min, then stopping heating, and continuously stir-frying until the temperature of the frying pan is reduced to the room temperature;
2) taking 30g of stir-fried dendrobe leaves, and soaking in 100ml of boiled water to obtain dendrobe leaf tea;
3) adding compound gentamycin oral liquid of Shandong mainland pharmaceutical industry Co Ltd (national Standard H10950228) into the dendrobe leaf tea, and stirring to obtain the antidiarrheal composition.
The antidiarrheal composition is taken as follows: the antidiarrheal composition is orally taken 1-2 times a day, and each time of the antidiarrheal composition contains 30g of dendrobium leaves.
Application example
The antidiarrheal composition for treating digestive disorders of the intestine of example 1 is used for conditioning patients with diarrhea, and has obvious curative effect, and typical cases are as follows:
1. the male is 49 years old, and the antidiarrheal composition of the invention 1 can stop diarrhea in about 20 minutes after being taken every time due to improper diet and frequent and multiple diarrhea, and has the efficacy of refreshing according to the oral administration of patients;
2. fossilia ectenes, female, age 29, with diarrhea symptoms 2 hours after dinner, feeling uncomfortable after going to toilet 2 times, and with the antidiarrheal composition of example 1, the diarrhea symptoms disappeared;
3. for a senior male, age 32, who may have diarrhea due to unknown causes, and who is aware of the possibility of continuing the diarrhea after having used the toilet many times, the antidiarrheal composition of example 1 is taken without diarrhea;
4. the diarrhea is often caused during the menstrual period of a woman aged to be red and the woman is 33 years old, the menstrual period is accompanied by abdominal pain, and the diarrhea causes the lassitude of the whole person and is very painful, so the diarrhea is avoided and the discomfort symptom during the menstrual period is relieved by taking the antidiarrheal composition of the embodiment 1 of the invention.

Claims (7)

1. An antidiarrheal composition for treating digestive disorders of the intestinal tract comprising: the composition consists of the following components:
30-35g of dendrobium leaves;
100ml of water;
one oral compound gentamicin liquid.
2. Antidiarrheal composition for the treatment of gut digestive disorders according to claim 1, characterized by: the compound gentamicin oral liquid is produced by Shandong mainland pharmaceutical industry Co Ltd, and is in the Chinese medicine standard H10950228.
3. Antidiarrheal composition for the treatment of gut digestive disorders according to claim 1, characterized by: the herba Dendrobii leaf is herba Dendrobii leaf.
4. Antidiarrheal composition for the treatment of gut digestive disorders according to claim 1, characterized by: the dendrobium leaves are dendrobium officinale leaves grafted on eucommia ulmoides trees.
5. A method of preparing an antidiarrheal composition according to claim 1 for the treatment of digestive disorders of the gut comprising: which comprises the following steps:
1) preparing dendrobium leaves: picking fresh dendrobe leaves, cutting the dendrobe leaves into strips with the thickness of 3-4mm after airing, then carrying out enzyme deactivation treatment, putting the dendrobe leaves subjected to enzyme deactivation treatment into a frying pan, stir-frying at the stir-frying temperature of 45-55 ℃ for 30-40min, then stopping heating, and continuously stir-frying until the temperature of the frying pan is reduced to room temperature;
2) taking 30-35g of stir-fried dendrobe leaves, and soaking in 100-400ml of boiled water to obtain dendrobe leaf tea;
3) and adding one compound gentamicin oral liquid into the dendrobium leaf tea, and uniformly stirring to obtain the antidiarrheal composition.
6. The method for preparing an antidiarrheal composition for the treatment of digestive disorders of the intestinal tract according to claim 5, wherein: the deactivation of enzymes of the dendrobium leaves is as follows: continuously parching herba Dendrobii leaf in pan of de-enzyming machine at 65-75 deg.C for 30-40 min.
7. A method of administering an antidiarrheal composition according to claim 1 for the treatment of digestive disorders of the gut comprising: the antidiarrheal composition is orally taken 1-2 times a day, and each time of the antidiarrheal composition contains 30-35g of dendrobium leaves.
CN201911419219.4A 2019-12-31 2019-12-31 Antidiarrheal composition for treating intestinal digestive diseases and preparation method thereof Pending CN111000943A (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1134833A (en) * 1995-12-22 1996-11-06 谢发林 Composite pharmaceutics for curing dysentery
CN102727815A (en) * 2012-06-01 2012-10-17 周孝意 Oral liquid for checking diarrhea and strengthening stomach
CN103609799A (en) * 2013-11-30 2014-03-05 桂平市白石洞天仙山铁皮石斛专业合作社 Method for preparing health-care dendrobium officinale tea from dendrobium officinale leaves
CN103735855A (en) * 2013-12-17 2014-04-23 浙江中医药大学 Traditional Chinese medicine composition containing dendrobium officinale leaves and flowers and application thereof
CN106509250A (en) * 2016-09-19 2017-03-22 中国农业科学院茶叶研究所 Processing method of concentrated dendrobium candidum leaf tea juice

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1134833A (en) * 1995-12-22 1996-11-06 谢发林 Composite pharmaceutics for curing dysentery
CN102727815A (en) * 2012-06-01 2012-10-17 周孝意 Oral liquid for checking diarrhea and strengthening stomach
CN103609799A (en) * 2013-11-30 2014-03-05 桂平市白石洞天仙山铁皮石斛专业合作社 Method for preparing health-care dendrobium officinale tea from dendrobium officinale leaves
CN103735855A (en) * 2013-12-17 2014-04-23 浙江中医药大学 Traditional Chinese medicine composition containing dendrobium officinale leaves and flowers and application thereof
CN106509250A (en) * 2016-09-19 2017-03-22 中国农业科学院茶叶研究所 Processing method of concentrated dendrobium candidum leaf tea juice

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ADMIN: "铁皮石斛叶子的吃法和功效", 《石斛百科》 *
哲学家的石头: "复方庆大霉素口服液", 《搜狗百科》 *

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Application publication date: 20200414