CN110882344A

CN110882344A - Traditional Chinese medicine formula for treating throat itching and cough and preparation method thereof

Info

Publication number: CN110882344A
Application number: CN201911382157.4A
Authority: CN
Inventors: 唐汉庆
Original assignee: YOUJIANG NATIONAL MEDICAL COLLEGE
Current assignee: YOUJIANG NATIONAL MEDICAL COLLEGE
Priority date: 2019-12-27
Filing date: 2019-12-27
Publication date: 2020-03-17

Abstract

The invention belongs to the field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine formula for treating pharynx itch and cough and a preparation method thereof. The traditional Chinese medicine formula is prepared from the following raw material components: the material is prepared from the following raw materials: fructus Schisandrae chinensis, Bulbus Fritillariae Cirrhosae, ramulus Cinnamomi, semen Armeniacae amarum, pericarpium Citri Tangerinae, herba Menthae, and radix Glycyrrhizae Preparata. The traditional Chinese medicine formula for treating the pharynx itch cough is simple in medicine flavor, easy to absorb, simple to process and easy to popularize, and has both short-term curative effect and long-term curative effect on the pharynx itch cough.

Description

Traditional Chinese medicine formula for treating throat itching and cough and preparation method thereof

[ technical field ] A method for producing a semiconductor device

The invention relates to the field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine formula for treating pharynx itch and cough and a preparation method thereof.

[ background of the invention ]

The cough with throat itching is different from the common cough and is characterized in that the cough is caused by itching, the throat itching is caused by the cough, the cough is firstly followed by the throat itching, and the cough is reduced after the cough; cough is manifested as paroxysmal cough, even spasmodic cough, or accompanied by dry throat, pharyngalgia, or hoarse voice, no or little phlegm, sticky phlegm, and brings great trouble to life, work and study.

At present, the treatment for the pharynx itch and cough is mainly based on the medication. Western medicines are most commonly used for treating leukotriene drugs and antihistamines, and have obvious short-term effect, but are easy to cause immune disorder and drug dependence problems after being treated, so that the control effect of long-term symptoms is not ideal. The recent treatment by adopting traditional Chinese medicines has certain advantages, the pharynx itch cough belongs to the categories of wind cough, pharyngitis and the like in the traditional Chinese medicine, the symptoms are caused by the interaction of internal deficiency and external evil, the pathogenesis mainly refers to spleen qi deficiency, lung and kidney yin deficiency and external infection wind evil, and the pathogenesis and clinical manifestation of the cough are different from those of the common cough. However, the traditional Chinese medicine formula for treating the cough with the throat itching focuses on the pathogenesis of the intermingled phlegm and heat, and ignores the pathogenesis of the deficiency of the spleen, the lung and the kidney and the external wind evil to a certain extent, so that the commonly used heat-clearing, phlegm-reducing and cough-relieving medicines have unsatisfactory effects on treating the cough with the throat itching.

In addition, some traditional Chinese medicine formulas for throat itching and cough have more medicine flavor and higher medicine cost, or part of the components have low bioavailability and are difficult to absorb; and the processing technology of the traditional Chinese medicine prescription components aiming at the symptoms of throat itching and cough is complicated, time-consuming and labor-consuming, and causes certain difficulty in popularization and application.

Therefore, aiming at the treatment of the cough with the throat itching, the pathogenesis needs to be comprehensively mastered, the pathogenesis of the deficiency of the spleen and the lung and the exogenous wind pathogen needs to be considered, and the pathogenesis of the exogenous wind pathogen also needs to be considered, so that the short-term curative effect and the long-term curative effect can be ensured to be considered in the treatment of the cough with the throat itching; the problems of easy absorption, simple processing and easy popularization need to be considered in the aspect of dosage form selection.

[ summary of the invention ]

The invention aims to: aiming at the defects of the prior art, the traditional Chinese medicine formula for treating the cough with the throat itching and the preparation method thereof are provided, the traditional Chinese medicine formula for treating the cough with the throat itching is simple in medicine flavor, easy to absorb, simple to process and easy to popularize, and both short-term curative effect and long-term curative effect are achieved in the aspect of treating the cough with the throat itching.

In order to achieve the purpose, the technical scheme adopted by the invention is as follows:

a traditional Chinese medicine formula for treating pharynx itch and cough is prepared from the following raw material components: fructus Schisandrae chinensis, Bulbus Fritillariae Cirrhosae, ramulus Cinnamomi, semen Armeniacae amarum, pericarpium Citri Tangerinae, herba Menthae, and radix Glycyrrhizae Preparata.

Further, the feed additive is prepared from the following raw material components in parts by weight: 14-16 parts of schisandra chinensis, 12-14 parts of bulbus fritilariae, 4-6 parts of cassia twig, 8-10 parts of almond, 3-5 parts of dried orange peel, 3-5 parts of mint and 1-3 parts of honey-fried licorice root.

Preferably, the feed is prepared from the following raw material components in parts by weight: 15 parts of schisandra chinensis, 13 parts of bulbus fritillariae cirrhosae, 5 parts of cassia twig, 9 parts of almond, 4 parts of pericarpium citri reticulatae, 4 parts of mint and 2 parts of honey-fried licorice root.

The preparation method of the traditional Chinese medicine formula for treating pharynx itch and cough comprises the following steps: (1) soaking 6 Chinese medicinal materials including fructus Schisandrae chinensis, ramulus Cinnamomi, semen Armeniacae amarum, pericarpium Citri Tangerinae, herba Menthae and radix Glycyrrhizae Preparata in clear water in casserole for 15-20 min, heating to boil, decocting with slow fire for 30-40 min, and filtering; adding appropriate amount of water into the residue, decocting with slow fire for 30-40 min, filtering, and mixing the filtrates;

(2) cleaning Bulbus Fritillariae Cirrhosae, air drying, crushing, grinding into fine powder, and sieving with 600-mesh and 800-mesh sieve to obtain Bulbus Fritillariae Cirrhosae powder;

(3) adding the bulbus fritillariae cirrhosae powder obtained in the step (2) into the filtrate obtained in the step (1), and concentrating to the relative density of 1.20-1.40 to obtain the bulbus fritillariae cirrhosae powder.

The invention also provides a preparation method of another traditional Chinese medicine formula for treating pharynx itch and cough, which comprises the following steps: (1) soaking 6 Chinese medicinal materials including fructus Schisandrae chinensis, ramulus Cinnamomi, semen Armeniacae amarum, pericarpium Citri Tangerinae, herba Menthae and radix Glycyrrhizae Preparata in clear water in casserole for 15-20 min, heating to boil, decocting with slow fire for 30-40 min, and filtering; adding appropriate amount of water into the residue, decocting with slow fire for 30-40 min, filtering, and mixing the filtrates;

(3) adding the bulbus fritillariae cirrhosae powder obtained in the step (2) into the filtrate obtained in the step (1), concentrating until the relative density is 1.20-1.40, adding honey, uniformly mixing, preparing into concentrated pills, and carrying out aseptic packaging to obtain the bulbus fritillariae cirrhosae powder. The drug effects of the medicines in the formula are as follows:

schisandra chinensis: the five herbs are salty in flavor and enter heart, lung and kidney meridians. Sour-salty food enters liver to tonify kidney, pungent food enters heart to tonify lung, sweet food enters middle energizer to benefit spleen and stomach. The functional indications are as follows: astringe lung to stop cough, nourish essence, check diarrhea and stop sweating. "Wu Wei Zi is the essential cough herb recorded in materia medica original prescription, and is used for cough due to wind-cold, summer-heat, dryness, fatigue, kidney-water, kidney-fire, chronic cough, dyspnea and dyspnea.

Tendril-leaved fritillary bulb: cool in nature, sweet and neutral. Enter lung and stomach meridians. The functional indications are as follows: moisten lung to arrest cough, resolve phlegm and relieve asthma. It can be used for treating cough with excessive phlegm and dry throat; cough due to wind; cough and dyspnea in children; swelling of sore throat; pulmonary abscess and pulmonary impotence. The record of Shennong Ben Cao Jing records that the medicine is mainly used for treating typhoid fever, dysphoria, stranguria, pathogenic factors, hernia, pharyngitis, difficult milk, incised wound and wind spasm.

Cassia twig: pungent, sweet and warm. Enter lung, kidney, heart and bladder meridians. The functional indications are as follows: tonify kidney yang, activate blood and warm spleen and stomach. It is indicated for kidney yang deficiency, decline of vital gate fire, cold limbs and pulse, cold pain in abdomen, cold arthralgia and lumbago. The record of Shennong Ben Cao Jing records that the cassia twig, pungent and warm in flavor, governs the adverse rise of qi, stagnates qi and is blocked in the throat, vomits and absorbs, benefits the joints, tonifies middle-jiao and tonifies qi.

Almond: bitter in property and slightly warm in nature. Enter lung and large intestine meridians. The functional indications are as follows: dispel phlegm and relieve cough, relieve dyspnea, moisten intestines. It is indicated for cough due to exogenous pathogenic factor, dyspnea, throat impediment, constipation due to intestinal dryness. The book records that the cough is mainly coughing, the upper qi is thunder and ringing, the throat is blocked, the lower qi is downward, breast is produced, golden sores are caused, and the cold heart runs to the dolphin. Recorded in Yunnan materia Medica, the traditional Chinese medicine is used for stopping cough, eliminating phlegm, moistening lung, moistening intestines and stomach, eliminating flour accumulation, descending qi and treating infantile malnutrition.

Dried orange peel: pungent, bitter and warm. Enter lung, spleen and stomach meridians. The functional indications are as follows: dry dampness, resolve phlegm, regulate qi and strengthen spleen, regulate middle energizer. It is indicated for cough, dyspnea, abdominal distention or pain, dyspepsia, chest distress, abdominal distention, anorexia, loose stool, poor appetite, vomiting and diarrhea. The book of Ben Cao Hui Yan records that the flavor is pungent and good in property, so it can open the breath; the stomach is bitter and purgative, so it can remove phlegm; it is mild in temperature and good at dredging, so it can stop vomiting, relieve cough, strengthen spleen and harmonize stomach. Recorded in the book of the daily herbal medicine, "can dispel the pathogenic energy and purge, warm and tonify, eliminate diaphragm qi, resolve phlegm and saliva, harmonize spleen to relieve cough, and treat five stranguria".

Mint: cool in nature and pungent in flavor. Enter lung and liver meridians. Has effects of relieving sore throat, promoting eruption, clearing away wind-heat, dispersing stagnated liver qi, and activating qi-flowing. It is used to treat common cold, early stage of wind-heat, headache, measles, pharyngitis, aphtha, rubella, conjunctival congestion, and chest and hypochondrium distention.

Honey-fried licorice root: sweet and neutral. Enter lung, spleen, stomach and heart meridians. The functional indications are as follows: invigorating spleen and replenishing qi, moistening lung for arresting cough, clearing heat and detoxicating, relieving pain, and alleviating drug property. It is used to treat weakness of spleen and stomach, shortness of breath, hypodynamia, palpitation, cough, excessive phlegm, toxic heat, sore and ulcer, abdominal pain, spasm and pain of limbs.

Modern pharmacological studies show that the schisandra chinensis can effectively inhibit macrophage and neutrophil infiltration of lung tissues, regulate the expression of inflammatory factors and have good relieving effect on airway inflammation and cough and asthma.

The bulbus fritilariae is contained in a plurality of traditional Chinese medicine formulas or traditional Chinese medicine preparations for treating acute tracheitis, bronchitis and other diseases, the total alkaloid part of the bulbus fritilariae has obvious or very obvious cough relieving effect on the cough caused by the ammonia water of mice, has repairing effect on the pathological damage of the trachea of acute bronchitis animals and has inhibiting effect on the cough caused by the ammonia water and citric acid.

The ramulus Cinnamomi contains chemical components such as cinnamaldehyde, cinnamic acid, cinnamyl alcohol, protocatechuic acid, etc., and has pharmacological activities of resisting virus, resisting bacteria, reducing blood sugar, relieving fever, resisting inflammation, resisting allergy, resisting blood coagulation, resisting tumor, tranquilizing, resisting anxiety, lowering blood pressure, dilating blood vessel, protecting nerve, etc. Can be used for treating various diseases.

Amygdalin contained in almond is decomposed in human body to generate a trace amount of hydrocyanic acid, the hydrocyanic acid can inhibit respiratory center to make respiratory movement smooth, thereby having the effect of relieving cough and asthma.

The tangerine peel contains volatile oil, has irritation, has the effect of eliminating phlegm and facilitating expectoration, the tangerine peel decoction has weak expansion effect on bronchus, and the alcohol extract has high asthma relieving potency and strong anti-inflammatory effect.

The herba Menthae contains volatile oil, and the oil mainly contains menthol, menthone and menthyl esters. Has obvious cough relieving, inflammation diminishing and bacteriostasis effects on the upper respiratory tract infection.

Radix Glycyrrhizae Preparata contains glycyrrhizin, glycyrrhetinic acid, and Glycyrrhiza polysaccharide, and has antiinflammatory and antiallergic effects.

It has antiinflammatory and antiallergic effects, and can protect the inflamed throat and trachea mucosa of respiratory system. Has effects of repairing gastrointestinal mucosa and relieving spasm of smooth muscle of stomach and intestine. Simultaneously has tranquilizing, immunoregulating, immunity regulating, antitumor and analgesic effects.

In summary, due to the adoption of the technical scheme, the invention has the beneficial effects that:

(1) the invention sets up a prescription aiming at the etiology of 'external infection wind evil' of the pharynx itch cough and the pathogenesis of 'spleen-lung-kidney deficiency', has mild and lasting drug property and no side effect, considers short-term curative effect and long-term curative effect on the treatment of the pharynx itch cough, has simple prescription drug taste, easy absorption and simple processing, and is easy to carry and take after being processed into pills.

In the formula, the schisandra chinensis is sour and salty and enters the liver to tonify the kidney, pungent and bitter to enter the heart to tonify the lung, sweet to enter the middle uterus to strengthen the spleen and stomach; ramulus Cinnamomi is pungent, sweet and warm, and enters lung, kidney, heart and bladder meridians; the almond has bitter and slightly warm properties, enters lung and large intestine channels, and has the efficacies of warming yang, reducing phlegm, relieving cough and asthma. Pericarpium Citri Tangerinae, pungent, bitter and warm, enters lung, spleen and stomach meridians; prepared licorice root, radix Glycyrrhizae Praeparata, sweet and neutral, enters lung, spleen, stomach and heart meridians, and dried orange peel and prepared licorice root are used together to dispel phlegm, relieve spasm, relieve cough and asthma. Bulbus Fritillariae Cirrhosae is cool in nature, sweet and neutral, and enters lung and stomach meridians; the mint is cool in nature and pungent in flavor, enters lung and liver meridians, and is combined with the bulbus fritilariae and the mint to strengthen the effects of moistening lung, reducing phlegm, soothing wind and dissipating heat. The formula aims at the etiology of 'external infection wind evil' of pharynx itch and cough and the pathogenesis of 'spleen-lung-kidney deficiency', and achieves the comprehensive efficacies of relieving sore throat, relieving itching, relieving cough, reducing phlegm and relieving asthma by comprehensively grasping the etiology and pathogenesis and combining the medicines. Embodies the theoretical characteristics and treatment characteristics of syndrome differentiation treatment and integral treatment of the traditional Chinese medicine.

(2) Animal experiments prove that the formula has remarkable curative effect on pharynx itch and cough.

[ description of the drawings ]

FIG. 1 is a graph showing morphological changes of lung tissues in each group in example 5 of the present invention. Wherein, A is a control group; b, model group; c, low dose group; d, medium dose group; e high dose group

[ detailed description ] embodiments

Example 1

Prescription: 15 parts of schisandra chinensis, 13 parts of bulbus fritillariae cirrhosae, 5 parts of cassia twig, 9 parts of almond, 4 parts of pericarpium citri reticulatae, 4 parts of mint and 2 parts of honey-fried licorice root.

The preparation method comprises the following steps:

(1) 6 traditional Chinese medicines of schisandra chinensis, cassia twig, almond, dried orange peel, mint and honey-fried licorice root are placed in a marmite clear water for soaking for 18 minutes, then heated to boiling, decocted for 35 minutes by slow fire and filtered; adding appropriate amount of water into the residue, decocting with slow fire for 35 min, filtering, and mixing the filtrates;

(2) cleaning Bulbus Fritillariae Cirrhosae, air drying, crushing, grinding into fine powder, and sieving with 600 mesh sieve to obtain Bulbus Fritillariae Cirrhosae powder;

(3) and (3) adding the bulbus fritillariae cirrhosae powder obtained in the step (2) into the filtrate obtained in the step (1), and concentrating to the relative density of 1.30 to obtain the bulbus fritillariae cirrhosae powder.

Example 2

Prescription: 14 parts of schisandra chinensis, 14 parts of bulbus fritillariae cirrhosae, 4 parts of cassia twig, 10 parts of almond, 3 parts of pericarpium citri reticulatae, 5 parts of mint and 1 part of honey-fried licorice root.

The preparation method comprises the following steps:

(1) 6 traditional Chinese medicines of schisandra chinensis, cassia twig, almond, dried orange peel, mint and honey-fried licorice root are placed in a marmite clear water for soaking for 15 minutes, then heated to boiling, decocted for 30 minutes by slow fire and filtered; adding appropriate amount of water into the residue, decocting with slow fire for 40 min, filtering, and mixing the filtrates;

(2) cleaning Bulbus Fritillariae Cirrhosae, air drying, crushing, grinding into fine powder, and sieving with 800 mesh sieve to obtain Bulbus Fritillariae Cirrhosae powder;

(3) and (3) adding the bulbus fritillariae cirrhosae powder obtained in the step (2) into the filtrate obtained in the step (1), and concentrating to the relative density of 1.20 to obtain the bulbus fritillariae cirrhosae powder.

Example 3

Prescription: 16 parts of schisandra chinensis, 12 parts of bulbus fritillariae cirrhosae, 6 parts of cassia twig, 8 parts of almond, 5 parts of pericarpium citri reticulatae, 3 parts of mint and 3 parts of honey-fried licorice root.

The preparation method comprises the following steps:

(1) 6 traditional Chinese medicines of schisandra chinensis, cassia twig, almond, dried orange peel, mint and honey-fried licorice root are placed in a marmite clear water for soaking for 20 minutes, then heated to boiling, decocted for 40 minutes by slow fire and filtered; adding appropriate amount of water into the residue, decocting with slow fire for 30 min, filtering, and mixing the filtrates;

(3) and (3) adding the bulbus fritillariae cirrhosae powder obtained in the step (2) into the filtrate obtained in the step (1), and concentrating to the relative density of 1.40 to obtain the bulbus fritillariae cirrhosae powder.

Example 4

The preparation method comprises the following steps:

(3) adding the bulbus fritillariae cirrhosae powder obtained in the step (2) into the filtrate obtained in the step (1), concentrating to the relative density of 1.30, adding honey, uniformly mixing, preparing into concentrated pills, 6 g of each pill, and carrying out aseptic packaging to obtain the bulbus fritillariae cirrhosae powder.

Remarking: the "parts" numbers described in the above examples are all referred to as "parts by weight".

To demonstrate the therapeutic effect of the Chinese medicinal formulation of the present invention, the applicant conducted the following toxicological and pharmacodynamic experiments.

EXAMPLE 5 exemplary toxicological, pharmacodynamic and clinical treatment of the Chinese medicinal formulation of the present invention

1. Toxicology test of animals

(1) Acute poisoning test for animals

① test animals SPF BALB/c mice 100, half male and half female, body weight (20 + -2 g).

② test method comprises adding appropriate amount of double distilled water into pill, stirring, heating in water bath to obtain 20% Chinese medicinal liquid, intragastrically administering 20g/kg of body weight to mice with tolerance 100 times of clinical patients, slightly increasing activity of mice after administration for 35 min, recovering to normal after about 1 hr, continuously observing for 7 days, and administering via intragastrically administering to mice to achieve the effects of normal activity, normal diet, water intake, defecation and weight increase.

(2) Long term toxicity test in animals

① test animals SPF Wistar rat 90, male and female half, body weight (160 + -15 g).

② the test method comprises dividing rats into 3 groups of formula gavage administration low dose group (short for low dose group), formula gavage administration medium dose group (short for medium dose group), and formula gavage administration high dose group (short for high dose group), wherein each group contains 30 rats, adding appropriate amount of double distilled water into formula pill, stirring uniformly, heating in water bath to obtain 20% concentration Chinese medicinal liquid, wherein the unit weight gavage administration amounts of low dose, medium dose, and high dose group are respectively 0.5, 2, and 5 times of the equivalent dosage of clinical patients, performing continuous gavage administration for 180 days, performing blood biochemical detection on the rats, killing the rats after gavage, and performing blood biochemical detection on the rats, wherein the detection indexes comprise ALT activity, AST activity, Serum Creatinine (SCR), serum urea nitrogen (BUN), and urine creatinine (UCr), performing morphological observation on the rats by HE staining on liver and kidney tissue, taking 30 rats as normal control group, comparing the results of normal blood perfusion, and performing pathological observation on the rats, and comparing the results of the pathological blood biochemical observation and the pathological growth and the control group, and the pathological growth and the results of the rats.

2. Pharmacodynamic test of animals

① test animals, SPF class Kunming mice 50, half male and half female, body weight (18 + -2 g).

② test method comprises dividing mice into normal control group (for short, control group), pharynx itch cough animal model group (for short, model group), formula gastric perfusion administration low dose group (for short, low dose group), formula gastric perfusion administration medium dose group (for short, medium dose group), and formula gastric perfusion administration high dose group (for short, high dose group) 5 groups, each group containing 10 mice, performing asthma molding for the model groups, low dose, medium dose, and high dose groups, establishing pharynx itch cough mice model by ovalbumin intraperitoneal injection sensitization and atomization inhalation excitation method, adding appropriate amount of double distilled water into the formula pill, stirring uniformly, heating in water bath to obtain 20% concentration of Chinese medicinal liquid, and performing oral perfusion administration for low dose, medium dose, and high dose groups with unit weight gastric perfusion administration amounts respectively equal to 0.5, 2, 5 times of clinical patient equivalent amount, performing oral perfusion administration for the control group and the model group with physiological saline, performing continuous oral perfusion administration for 4 weeks, performing oral perfusion administration for the mice to detect immunoglobulin uk, and obtaining immunoglobulin and inflammation related to lung inflammation (Interleukin 4-10 IL 5, Interleukin-5-10-volume observation of lung tissue change, and IL-5-volume observation.

③ test results, wherein the results of statistical analysis show that each dose group has different degree of improvement on IgE, IL-4, IL-5 and IL-10 water average, approaches the level of the control group, and has statistical significance compared with the model group, the morphological observation result shows that the control group has clear bronchus and lung tissues, smooth tube wall, no blood vessel congestion and inflammatory cell infiltration, the model group has unclear bronchus and lung tissue structure, unsmooth tube wall and large inflammatory cell infiltration, each dose group has less alveolar exudate and lighter inflammatory cell infiltration degree, and has obvious improvement compared with the model group (the experimental results are shown in Table 1 and figure 1)

TABLE 1 comparison of IgE, IL-4, IL-5, IL-10 levels in each group: (

n＝10)

Note: comparison with model groups:^ΔP<0.05，^ΔΔP<0.01. comparison with the control group:^*P<0.05，^**P<0.01。

the formulation pellets used in this example were prepared from example 4.

3. Typical case of clinical treatment

(1) Old, female, 62 years old. The cough due to throat itching is aggravated by repeated attack for 2 years and the diagnosis is aggravated for 1 week. The patients have throat itching and dry cough after cold 1 month ago, the patients often feel dry mouth and polydipsia, and take the medicines of 'cough quick-stop, acute bronchitis syrup' and the like, and the cefazolin sodium and the ribavirin are dripped for a while, but the throat itching and the dry cough are not obviously relieved, and the patients are in treatment before. The patients have paroxysmal pharynx itch, dry cough without phlegm and dry mouth. No obvious abnormal change of chest film, red tongue with thin coating, and thready and rapid pulse. The four diagnostic methods are combined to differentiate the syndrome as "cough with wind type with throat itching". The pill with the formula is taken 6 pills (6 g per pill) every day, 2 times a day in the morning and evening, 3 pills are taken with warm boiled water each time, 7 days are 1 treatment course, after continuously taking for 4 treatment courses, symptoms of pharynx itch and dry cough disappear, symptoms of dry mouth and polydipsia are obviously relieved, and no relapse occurs after 1 year of follow-up visit.

(2) Lie, male, 9 years old. The patients have an electric fan after bathing for 7 days, and then have throat itching and dry cough, and the local clinic oral administration of the anti-inflammatory drug and the cough syrup has no obvious improvement on the treatment. Through the four diagnostic methods, the syndrome differentiation is "Houbi" (spleen deficiency with wind type) in TCM. The pill with the formula is taken 6 pills (6 g per pill) every day, 2 times a day in the morning and evening, 3 pills are taken with warm boiled water each time, 7 days are 1 course of treatment, 1 course of treatment is taken, after the course of treatment is finished, symptoms of pharynx itch and dry cough disappear, and no recurrence is seen in half a year after follow-up.

The above description is intended to describe in detail the preferred embodiments of the present invention, but the embodiments are not intended to limit the scope of the claims of the present invention, and all equivalent changes and modifications made within the technical spirit of the present invention should fall within the scope of the claims of the present invention.

Claims

1. The traditional Chinese medicine formula for treating throat itching and cough is characterized by being prepared from the following raw material components: fructus Schisandrae chinensis, Bulbus Fritillariae Cirrhosae, ramulus Cinnamomi, semen Armeniacae amarum, pericarpium Citri Tangerinae, herba Menthae, and radix Glycyrrhizae Preparata.

2. The traditional Chinese medicine formula for treating pharynx itch and cough according to claim 1, is characterized by being prepared from the following raw material components in parts by weight: 14-16 parts of schisandra chinensis, 12-14 parts of bulbus fritilariae, 4-6 parts of cassia twig, 8-10 parts of almond, 3-5 parts of dried orange peel, 3-5 parts of mint and 1-3 parts of honey-fried licorice root.

3. The traditional Chinese medicine formula for treating pharynx itch and cough according to claim 2, which is characterized by being prepared from the following raw material components in parts by weight: 15 parts of schisandra chinensis, 13 parts of bulbus fritillariae cirrhosae, 5 parts of cassia twig, 9 parts of almond, 4 parts of pericarpium citri reticulatae, 4 parts of mint and 2 parts of honey-fried licorice root.

4. The preparation method of the traditional Chinese medicine formula for treating pharynx itch and cough as claimed in any one of claims 1 to 3, characterized by comprising the following steps: (1) soaking 6 Chinese medicinal materials including fructus Schisandrae chinensis, ramulus Cinnamomi, semen Armeniacae amarum, pericarpium Citri Tangerinae, herba Menthae and radix Glycyrrhizae Preparata in clear water in casserole for 15-20 min, heating to boil, decocting with slow fire for 30-40 min, and filtering; adding appropriate amount of water into the residue, decocting with slow fire for 30-40 min, filtering, and mixing the filtrates;

5. The method for preparing a traditional Chinese medicine formula for treating pharynx itch and cough according to claim 4, is characterized by comprising the following steps: (1) soaking 6 Chinese medicinal materials including fructus Schisandrae chinensis, ramulus Cinnamomi, semen Armeniacae amarum, pericarpium Citri Tangerinae, herba Menthae and radix Glycyrrhizae Preparata in clear water in casserole for 15-20 min, heating to boil, decocting with slow fire for 30-40 min, and filtering; adding appropriate amount of water into the residue, decocting with slow fire for 30-40 min, filtering, and mixing the filtrates;

(3) adding the bulbus fritillariae cirrhosae powder obtained in the step (2) into the filtrate obtained in the step (1), concentrating until the relative density is 1.20-1.40, adding honey, uniformly mixing, preparing into concentrated pills, and carrying out aseptic packaging to obtain the bulbus fritillariae cirrhosae powder.