CN110832298B - 切片机和用于定位切片机标本头的方法 - Google Patents

切片机和用于定位切片机标本头的方法 Download PDF

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Publication number
CN110832298B
CN110832298B CN201880044186.7A CN201880044186A CN110832298B CN 110832298 B CN110832298 B CN 110832298B CN 201880044186 A CN201880044186 A CN 201880044186A CN 110832298 B CN110832298 B CN 110832298B
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China
Prior art keywords
specimen
specimen head
head
microtome
sensor
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CN201880044186.7A
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Chinese (zh)
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CN110832298A (zh
Inventor
马克-奥利弗·海因里希
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Leica Biosystems Nussloch GmbH
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Leica Biosystems Nussloch GmbH
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
    • G01N1/06—Devices for withdrawing samples in the solid state, e.g. by cutting providing a thin slice, e.g. microtome
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
    • G01N1/06—Devices for withdrawing samples in the solid state, e.g. by cutting providing a thin slice, e.g. microtome
    • G01N2001/065—Drive details
    • G01N2001/066—Drive details electric

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)
CN201880044186.7A 2017-11-30 2018-11-26 切片机和用于定位切片机标本头的方法 Active CN110832298B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102017128491.5 2017-11-30
DE102017128491.5A DE102017128491B4 (de) 2017-11-30 2017-11-30 Mikrotom und Verfahren zum Positionieren eines Mikrotomobjektkopfes
PCT/EP2018/082578 WO2019105894A1 (de) 2017-11-30 2018-11-26 Mikrotom und verfahren zum positionieren eines mikrotomobjektkopfes

Publications (2)

Publication Number Publication Date
CN110832298A CN110832298A (zh) 2020-02-21
CN110832298B true CN110832298B (zh) 2024-02-13

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CN201880044186.7A Active CN110832298B (zh) 2017-11-30 2018-11-26 切片机和用于定位切片机标本头的方法

Country Status (6)

Country Link
US (1) US11467068B2 (enExample)
EP (1) EP3625533B1 (enExample)
JP (1) JP7193485B2 (enExample)
CN (1) CN110832298B (enExample)
DE (1) DE102017128491B4 (enExample)
WO (1) WO2019105894A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4281047A1 (en) 2021-01-21 2023-11-29 XSpray Pharma AB (publ) Fast dissolving pharmaceutical compositions of dasatinib

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0937975A2 (en) * 1998-02-18 1999-08-25 Shandon Scientific Limited Microtome
CN1268423A (zh) * 1999-03-12 2000-10-04 莱卡显微系统努斯洛赫股份有限公司 带有电动进给驱动装置的切片机
CN1271092A (zh) * 1999-03-12 2000-10-25 莱卡显微系统努斯洛赫股份有限公司 切片机
CN101223011A (zh) * 2005-06-29 2008-07-16 浦瑞玛柯Feg有限责任公司 具有动力食物托架的可编程切片机
TW200906537A (en) * 2007-06-01 2009-02-16 Union Tool Co Ltd Rotary cutting tool and method of detecting reference position
CN102213826A (zh) * 2010-04-07 2011-10-12 索尼公司 镜台控制设备、镜台控制方法和显微镜
CN102692338A (zh) * 2011-03-24 2012-09-26 美国樱花检验仪器株式会社 具有检测样品表面取向的表面取向传感器的切片机
CN103379619A (zh) * 2012-04-16 2013-10-30 中兴通讯股份有限公司 一种定位方法和系统
CN104081181A (zh) * 2011-12-21 2014-10-01 美国樱花检验仪器株式会社 往复式切片机驱动系统
CN104511924A (zh) * 2013-10-03 2015-04-15 株式会社岛精机制作所 裁断机及其裁断头升降控制方法
CN104596796A (zh) * 2013-10-31 2015-05-06 希森美康株式会社 吸移部件的位置调整方法及样本处理装置

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3884563A (en) 1971-04-07 1975-05-20 Fox John C Microtome with rotating knife
DE3830725A1 (de) 1988-09-09 1990-03-22 Leitz Wild Gmbh Automatische arretierung der antriebseinrichtung eines mikrotoms
AT399226B (de) 1990-04-11 1995-04-25 Sitte Hellmuth Automatische anschneidevorrichtung für mikrotome, insbesondere ultramikrotome
US5535654A (en) * 1991-11-28 1996-07-16 Microm Laborgerate Gmbh Microtome
DE19528180C2 (de) 1995-08-01 1997-06-19 Microm Laborgeraete Gmbh Kryostat-Mikrotom und Verfahren zum Betrieb eines Kryostat-Mikrotoms
EP0920613B1 (de) 1996-07-29 2002-10-02 Leica Microsystems Nussloch GmbH Scheiben-mikrotom
DE19911005A1 (de) 1999-03-12 2000-09-28 Leica Microsystems Verfahren zur Steuerung eines Scheibenmikrotoms
GB0030310D0 (en) 2000-12-13 2001-01-24 Medical Res Council Apparatus and method for imaging a histological sample
US7372985B2 (en) * 2003-08-15 2008-05-13 Massachusetts Institute Of Technology Systems and methods for volumetric tissue scanning microscopy
DE102005042367B4 (de) 2005-09-07 2009-11-12 Leica Microsystems Cms Gmbh Vorrichtung zum Erzeugen von 3-D Bildern einer Probe
DE102008016165B4 (de) * 2008-03-28 2010-10-14 Leica Biosystems Nussloch Gmbh Mikrotom mit variablem Schneidehub unter Verwendung eines Linearmotors als Antrieb
US8352212B2 (en) * 2009-11-18 2013-01-08 Hexagon Metrology, Inc. Manipulable aid for dimensional metrology
DE102010046498B3 (de) * 2010-09-24 2011-12-15 Hans Heid Schneidehubverstellung eines Rotationsmikrotoms
DE102012106845B4 (de) * 2012-07-27 2014-08-07 Leica Biosystems Nussloch Gmbh Mikrotom mit Auto-Rocking-Modus
DE102013110776B4 (de) 2013-09-30 2015-05-13 Leica Biosystems Nussloch Gmbh Verfahren und Mikrotom zum Herstellen von Dünnschnitten mit einem Schnittprofilaufzeichnungsmodus
US9933339B2 (en) * 2014-05-12 2018-04-03 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Miniature serial sectioning microtome for block-face imaging

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0937975A2 (en) * 1998-02-18 1999-08-25 Shandon Scientific Limited Microtome
CN1268423A (zh) * 1999-03-12 2000-10-04 莱卡显微系统努斯洛赫股份有限公司 带有电动进给驱动装置的切片机
CN1271092A (zh) * 1999-03-12 2000-10-25 莱卡显微系统努斯洛赫股份有限公司 切片机
CN101223011A (zh) * 2005-06-29 2008-07-16 浦瑞玛柯Feg有限责任公司 具有动力食物托架的可编程切片机
TW200906537A (en) * 2007-06-01 2009-02-16 Union Tool Co Ltd Rotary cutting tool and method of detecting reference position
CN102213826A (zh) * 2010-04-07 2011-10-12 索尼公司 镜台控制设备、镜台控制方法和显微镜
CN102692338A (zh) * 2011-03-24 2012-09-26 美国樱花检验仪器株式会社 具有检测样品表面取向的表面取向传感器的切片机
CN104081181A (zh) * 2011-12-21 2014-10-01 美国樱花检验仪器株式会社 往复式切片机驱动系统
CN103379619A (zh) * 2012-04-16 2013-10-30 中兴通讯股份有限公司 一种定位方法和系统
CN104511924A (zh) * 2013-10-03 2015-04-15 株式会社岛精机制作所 裁断机及其裁断头升降控制方法
CN104596796A (zh) * 2013-10-31 2015-05-06 希森美康株式会社 吸移部件的位置调整方法及样本处理装置

Also Published As

Publication number Publication date
CN110832298A (zh) 2020-02-21
DE102017128491A1 (de) 2019-06-06
WO2019105894A1 (de) 2019-06-06
DE102017128491B4 (de) 2022-12-22
EP3625533B1 (de) 2022-12-28
JP7193485B2 (ja) 2022-12-20
JP2021504671A (ja) 2021-02-15
US20210140854A1 (en) 2021-05-13
US11467068B2 (en) 2022-10-11
EP3625533A1 (de) 2020-03-25

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