CN110772579A - Traditional Chinese medicine herbal composition for treating soft tissue injury and preparation method thereof - Google Patents
Traditional Chinese medicine herbal composition for treating soft tissue injury and preparation method thereof Download PDFInfo
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- CN110772579A CN110772579A CN201911190253.9A CN201911190253A CN110772579A CN 110772579 A CN110772579 A CN 110772579A CN 201911190253 A CN201911190253 A CN 201911190253A CN 110772579 A CN110772579 A CN 110772579A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
- A61K31/125—Camphor; Nuclear substituted derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Abstract
The invention discloses a traditional Chinese medicine herbal composition for treating soft tissue injury and a preparation method thereof, wherein the traditional Chinese medicine herbal composition comprises camellia seed oil, white wax, menthol, natural borneol and natural camphor; wherein, the weight percentage of the components is as follows: 15 to 40 percent of camellia seed oil, 0.1 to 15 percent of white wax, 25 to 45 percent of menthol, 10 to 30 percent of natural borneol and 10 to 30 percent of natural camphor; the traditional Chinese medicine herbal composition for treating soft tissue injury is cream-shaped ointment or liquid medicinal oil, the formula is simple and scientific, the use is convenient, the dosage of the medicine is relatively reduced, the affected part can be kneaded, the medicine is fully absorbed, and the treatment effect is ideal; the preparation method can reduce the processing time, reduce the energy consumption, and the volatilization and loss of the raw materials, improve the quality and the stability of the ointment, and has the effects of relieving pain, eliminating swelling, relieving itching, removing blood stasis and the like.
Description
Technical Field
The invention relates to the technical field of medicinal preparations, in particular to a traditional Chinese medicine herbal composition for treating soft tissue injury and a preparation method thereof.
Background
Various natural traditional Chinese medicine herbaceous plants contain effective components for treating diseases, and the application range is very wide. For treating diseases such as soft tissue injury, the effective components of Chinese herbal medicines are usually extracted and purified, and then mixed appropriately to prepare various external preparations for applying on the skin surface of the affected part. In order to enhance the therapeutic effect, the external preparation is generally prepared into liquid or patch forms such as liquid medicine, tincture, medicinal oil, etc. The liquid medicine, tincture and medicinal oil have liquidity, are easy to waste due to pouring, and are easy to wear and inconvenient to use when being applied to an affected part in a smearing way; the medicine has the advantages of less volatile effective components, reduced permeation amount, easy absorption by foreign matters during matching hot compress, and incapability of fully exerting the medicine effect, and can be used under corresponding matched conditions to fully exert the medicine effect. The patch type medicine is coated on the affected part when in use, has poor air permeability, and is easy to be allergic and inflamed; in treatment, the medicament of the dosage form is always applied to an affected part and cannot be directly rubbed and kneaded, and the rubbing and kneading can cause excessive release of the medicament in a very short time to damage the affected part; the affected part cannot be kneaded, so that the medicine can only be used for treating the skin surface, and the internal curative effect is difficult to be exerted, thereby reducing the curative effect of the medicine.
A preparation method of a traditional Chinese herbal composition for treating soft tissue injury. The camellia seed oil is heated to 60-70 ℃ and continuously heated, solid white wax is placed in the camellia seed oil to be melted and mixed, then solid borneol is placed in the camellia seed oil to be melted and mixed, solid camphor is placed in the camellia seed oil to be melted and mixed, then the camellia seed oil is heated to about 100 ℃, during the period, the solid white wax is added until the solid camphor is added, the time of melting and mixing is about 10 minutes, then the heating is stopped, the solid menthol is added to be melted and mixed, and the camellia seed oil is cooled to the room temperature to form cream-shaped ointment or medicinal oil. The method has higher required temperature and higher energy consumption; the solid borneol, the solid borneol and the solid camphor have low solubility at about 100 ℃, and the time for dissolving and mixing is long; the higher the temperature of the dissolved mixed solution is, the volatilization and loss of the three medicinal components are easily caused, and the product quality and the stability are reduced.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine herbal composition for treating soft tissue injury and a preparation method thereof, and aims to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme:
a Chinese medicinal composition for treating soft tissue injury comprises oleum Camelliae Japonicae, Cera chinensis, Mentholum, natural Borneolum Syntheticum and natural Camphora; wherein, the weight percentage of the components is as follows: 15 to 40 percent of camellia seed oil, 0.1 to 15 percent of white wax, 25 to 45 percent of menthol, 10 to 30 percent of natural borneol and 10 to 30 percent of natural camphor.
As a preferred technical scheme of the invention, the traditional Chinese medicine herbal composition contains the following components: 30% of camellia seed oil, 0.5% of white wax, 25% of menthol, 20.5% of natural borneol and 24% of natural camphor.
As a preferred technical scheme of the invention, the traditional Chinese medicine herbal composition contains the following components: 20% of camellia seed oil, 1% of white wax, 35% of menthol, 23% of natural borneol and 21% of natural camphor.
The invention also provides a preparation method of the traditional Chinese medicine herbal composition for treating soft tissue injury, which comprises the following operation steps:
s1: the following components are respectively weighed according to the following mass percentages: 30% of camellia seed oil, 0.5% of white wax, 25% of menthol, 20.5% of natural borneol and 24% of natural camphor.
S2: heating the camellia seed oil weighed in the S1 to 60-70 ℃, adding white wax into the hot camellia seed oil under the condition of keeping the temperature, and dissolving and uniformly mixing the white wax and the hot camellia seed oil;
s3: averagely dividing the menthol weighed in the step S1 into two parts, respectively stirring the two parts at normal temperature with the natural borneol and the natural camphor weighed in the step S1 to dissolve the menthol and the natural borneol together, mixing the co-melted menthol-natural borneol and the co-melted menthol-natural camphor together, and uniformly stirring the mixture to form the co-melted menthol-natural borneol-natural camphor solution, wherein the co-melted menthol-natural borneol and the co-melted menthol-natural camphor can be heated to 45 ℃ in winter due to low air temperature, so that the co-dissolution phenomenon can be promoted, and the co-dissolution time can be shortened;
s4: adding the co-solution of menthol-natural borneol-natural camphor in S3 into the mixed solution of camellia seed oil-white wax at 60-70 ℃ in S3, stirring and mixing uniformly to obtain the traditional Chinese medicine herbal composition;
s5: and (4) subpackaging the traditional Chinese medicine herbal composition prepared in the step (S4) into a suitable container, and cooling to room temperature to obtain a white cream ointment or transparent liquid medicinal oil.
The medicine properties of the traditional Chinese medicines used by the invention are as follows:
and (3) camellia seed oil: the camellia seed oil is edible oil with the most abundant unsaturated fatty acid units, contains abundant protein, vitamin A, E and the like, has good stability and lubrication effect, can make the skin of a person smooth and moist, and has the effects of sterilizing, detoxifying, accelerating wound healing and the like.
White wax: has hemostatic and granulation promoting effects, and is a hardening agent for coagulating the molten medicinal liquid.
Menthol: is extracted from leaf and stem of herba Menthae, and can be used as irritant in medicine, and has effects of refreshing, relieving itching, and relieving pain locally for external use.
Natural borneol: a medicinal material with cold property has effects of tonifying heart, promoting blood circulation, relieving swelling and pain, and preventing putrefaction. The traditional Chinese medicine herbal composition has the effects of relieving swelling and pain and promoting drug effect circulation.
Natural camphor: the product is a granule prepared from root, trunk, branch, and leaf of Cinnamomum camphora (L.) Presl of Lauraceae by distilling and refining. The functions are mainly as follows: inducing resuscitation and removing filth, killing parasites and relieving itching. It is indicated for cold-damp beriberi, chilblain, scald due to hot liquid or fire, traumatic injury and pain. It is mainly used for treating beriberi.
Compared with the prior art, the invention has the beneficial effects that:
the invention has simple and scientific formula, convenient use and ideal treatment effect; the preparation method can reduce the processing time, reduce the energy consumption, and the volatilization and loss of the raw materials, improve the quality and the stability of the ointment, and has the effects of relieving pain, eliminating swelling, relieving itching, removing blood stasis and the like.
Detailed Description
The technical solutions in the embodiments of the present invention are clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1: the invention provides a technical scheme that: a Chinese medicinal composition for treating soft tissue injury comprises oleum Camelliae Japonicae, Cera chinensis, Mentholum, natural Borneolum Syntheticum and natural Camphora; wherein, the weight percentage of the components is as follows: 15 to 40 percent of camellia seed oil, 0.1 to 15 percent of white wax, 25 to 45 percent of menthol, 10 to 30 percent of natural borneol and 10 to 30 percent of natural camphor.
As a preferred technical scheme of the invention, the traditional Chinese medicine herbal composition comprises the following components: 30% of camellia seed oil, 0.5% of white wax, 25% of menthol, 20.5% of natural borneol and 24% of natural camphor.
As a preferred technical scheme of the invention, the traditional Chinese medicine herbal composition comprises the following components: 20% of camellia seed oil, 1% of white wax, 35% of menthol, 23% of natural borneol and 21% of natural camphor.
The invention also provides a preparation method of the traditional Chinese medicine herbal composition for treating soft tissue injury, which comprises the following operation steps:
s1: the following components are respectively weighed according to the following mass percentages: 30% of camellia seed oil, 0.5% of white wax, 25% of menthol, 20.5% of natural borneol and 24% of natural camphor.
S2: heating the camellia seed oil weighed in the S1 to 60-70 ℃, adding white wax into the hot camellia seed oil under the condition of keeping the temperature, and dissolving and uniformly mixing the white wax and the hot camellia seed oil;
s3: averagely dividing the menthol weighed in the step S1 into two parts, respectively stirring the two parts at normal temperature with the natural borneol and the natural camphor weighed in the step S1 to dissolve the menthol and the natural borneol together, mixing the co-melted menthol-natural borneol and the co-melted menthol-natural camphor together, and uniformly stirring the mixture to form the co-melted menthol-natural borneol-natural camphor solution, wherein the co-melted menthol-natural borneol and the co-melted menthol-natural camphor can be heated to 45 ℃ in winter due to low air temperature, so that the co-dissolution phenomenon can be promoted, and the co-dissolution time can be shortened;
s4: adding the co-solution of menthol-natural borneol-natural camphor in S3 into the mixed solution of camellia seed oil-white wax at 60-70 ℃ in S3, stirring and mixing uniformly to obtain the traditional Chinese medicine herbal composition;
s5: and (4) subpackaging the traditional Chinese medicine herbal composition prepared in the step (S4) into a suitable container, and cooling to room temperature to obtain a white cream ointment or transparent liquid medicinal oil.
The traditional Chinese medicine herbal composition for treating soft tissue injury prepared by the invention has the following using effects:
1. personnel select and administer the medication: 8 patients with consistent tissue injury degree are selected, 4 patients are provided with the pure natural traditional Chinese medicine herbal composition for treating soft tissue injury prepared by the invention, and the other 4 patients are provided with the traditional Chinese medicine herbal composition for treating soft tissue injury, and the using method is as follows: preparing a medical sterile glove and a sterile medicine spoon; the traditional Chinese medicine herbal composition for treating soft tissue injury is uniformly smeared on the injured part of a patient by a medicine spoon with sterile gloves, and the patient is kept warm; in addition, 4 patients are smeared on the affected part of the patient by the same operation of the traditional Chinese herbal composition for treating the soft tissue injury; the two medicines are applied for 2 hours, so that the liquid medicine is fully dispersed to the affected part, the two medicines are applied twice every day, 7 days are taken as a treatment course, the use feedback of the patient is recorded every day, and the change of the pain symptom of the patient before and after treatment is recorded.
2. The treatment results are as follows: after 4 Chinese herbal medicine compositions for treating soft tissue injury prepared by the invention are used for one week, 4 patients obviously feel pain relief of the injured part, and in addition, 4 patients do not obviously feel pain reduction after being used for one week by using traditional Chinese herbal medicine compositions for treating soft tissue injury.
Example 2: the invention provides a traditional Chinese medicine herbal composition for treating soft tissue injury, which comprises the following components: 20% of camellia seed oil, 1% of white wax, 35% of menthol, 23% of natural borneol and 21% of natural camphor.
The preparation method comprises the following steps:
x21: heating 20% of camellia seed oil to 60-70 ℃, adding 1% of white wax into the hot camellia seed oil under the condition of keeping the temperature, and dissolving and uniformly mixing the white wax and the hot camellia seed oil;
x22: the method comprises the following steps of averagely dividing 35% of menthol into two parts, respectively stirring the two parts at normal temperature with 23% of natural borneol and 21% of natural camphor to dissolve the menthol and the natural borneol together, mixing the menthol-natural borneol co-melting liquid with the menthol-natural camphor co-melting liquid, and uniformly stirring the mixture to form the menthol-natural borneol-natural camphor co-melting liquid, wherein the menthol-natural borneol-natural camphor co-melting liquid can be heated to 45 ℃ in winter due to low temperature, so that the co-dissolving phenomenon can be promoted, and the co-dissolving time can be shortened;
x23: adding the co-solution of menthol-natural borneol-natural camphor in the X22 into the mixed solution of camellia seed oil-white wax in the X21 at the temperature of 60-70 ℃, stirring and mixing uniformly to prepare the traditional Chinese medicine herbal composition;
x24: subpackaging the Chinese medicinal herb composition prepared in the step X23 into a suitable container, and cooling to room temperature to obtain a white cream ointment or a transparent liquid medicinal oil.
Example 2 is the same as the above examples in material and processing steps, but the ratio of the two is different.
Example 3: the invention provides a traditional Chinese medicine herbal composition for treating soft tissue injury, which comprises the following components: 20% of camellia seed oil, 1% of white wax, 35% of menthol, 23% of natural borneol and 21% of natural camphor.
The preparation method comprises the following steps:
x31: heating 20% of camellia seed oil to 60-70 ℃, continuously heating, adding 1% of white wax into the hot camellia seed oil, and dissolving and uniformly mixing the white wax and the hot camellia seed oil;
x32: adding 23% of natural borneol into the mixed liquid of camellia seed oil and white wax in X31 at the temperature of 60-70 ℃, adding 21% of natural camphor after the natural borneol is melted and mixed, melting and mixing the natural camphor, heating to about 100 ℃, adding solid white wax into the mixed liquid for about 10 minutes from the time of adding the solid white wax, and stopping heating;
x33: adding 35% Mentholum into mixture of SHANCHAYEZI oil, white wax, natural Borneolum Syntheticum and natural Camphora in X32, mixing, cooling to room temperature, and making into ointment or medicinal oil.
The materials and the mixture ratio of the embodiment 3 are the same as those of the embodiment 2, and the difference is that the processing steps of the two are different.
Example 4: the invention provides a traditional Chinese medicine herbal composition for treating soft tissue injury, which comprises the following components: 30% of camellia seed oil, 0.5% of white wax, 25% of menthol, 20.5% of natural borneol and 24% of natural camphor.
The preparation method comprises the following steps:
x41: heating 30% of camellia seed oil to 60-70 deg.C, heating continuously, adding 0.5% of white wax into the hot camellia seed oil, melting, and mixing;
x42: adding 20.5% natural borneol into the mixed liquid of camellia seed oil and white wax at 60-70 ℃ in X31, adding 24% natural camphor after the natural borneol is melted and mixed, melting and mixing the natural camphor and the natural camphor, heating to about 100 ℃, wherein the time for melting and mixing is about 10 minutes from the addition of the solid white wax to the addition of the solid camphor, and then stopping heating;
x43: adding 25% menthol into mixture of SHANCHAYEZI oil, white wax, natural Borneolum Syntheticum and natural Camphora in X32, dissolving, mixing, cooling to room temperature, and making into ointment or medicinal oil.
Example 4 is the same as example 3 in material and processing steps, but different in the mixture ratio.
The herbal compositions for treating soft tissue injury prepared according to the formulation and preparation methods described in examples 1-4 were tested for pain relief and swelling reduction, and the results were evaluated at A, B, C, D, as shown in the following table:
as can be seen from the table, the herbal compositions for treating soft tissue injury prepared according to the processing steps of example 1 and example 2 are effective in relieving pain and decreasing swelling.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (4)
1. A Chinese medicinal herbal composition for treating soft tissue injury is characterized by comprising camellia seed oil, white wax, menthol, natural borneol and natural camphor; wherein, the weight percentage of the components is as follows: 15 to 40 percent of camellia seed oil, 0.1 to 15 percent of white wax, 25 to 45 percent of menthol, 10 to 30 percent of natural borneol and 10 to 30 percent of natural camphor.
2. The herbal composition for the treatment of soft tissue injury as claimed in claim 1, consisting of, in weight percent: 30% of camellia seed oil, 0.5% of white wax, 25% of menthol, 20.5% of natural borneol and 24% of natural camphor.
3. The herbal composition for the treatment of soft tissue injury as claimed in claim 1, consisting of, in weight percent: 20% of camellia seed oil, 1% of white wax, 35% of menthol, 23% of natural borneol and 21% of natural camphor.
4. The method of preparing a herbal composition for soft tissue injury as claimed in claim 1, comprising the steps of:
s1: the following components are respectively weighed according to the following mass percentages: 30% of camellia seed oil, 0.5% of white wax, 25% of menthol, 20.5% of natural borneol and 24% of natural camphor.
S2: heating the camellia seed oil weighed in the S1 to 60-70 ℃, adding white wax into the hot camellia seed oil under the condition of keeping the temperature, and dissolving and uniformly mixing the white wax and the hot camellia seed oil;
s3: averagely dividing the menthol weighed in the step S1 into two parts, respectively stirring the two parts at normal temperature with the natural borneol and the natural camphor weighed in the step S1 to dissolve the menthol and the natural borneol together, mixing the co-melted menthol-natural borneol and the co-melted menthol-natural camphor together, and uniformly stirring the mixture to form the co-melted menthol-natural borneol-natural camphor solution, wherein the co-melted menthol-natural borneol and the co-melted menthol-natural camphor can be heated to 45 ℃ in winter due to low air temperature, so that the co-dissolution phenomenon can be promoted, and the co-dissolution time can be shortened;
s4: adding the co-solution of menthol-natural borneol-natural camphor in S3 into the mixed solution of camellia seed oil-white wax at 60-70 ℃ in S3, stirring and mixing uniformly to obtain the traditional Chinese medicine herbal composition;
s5: and (4) subpackaging the traditional Chinese medicine herbal composition prepared in the step (S4) into a suitable container, and cooling to room temperature to obtain a white cream ointment or transparent liquid medicinal oil.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1439382A (en) * | 2002-02-21 | 2003-09-03 | 吴万春 | Chinese medicinal herb paste for fractures and preparation thereof |
| CN107638486A (en) * | 2017-08-30 | 2018-01-30 | 张�林 | A kind of Chinese medicine medicine oil and preparation method thereof |
-
2019
- 2019-11-28 CN CN201911190253.9A patent/CN110772579A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1439382A (en) * | 2002-02-21 | 2003-09-03 | 吴万春 | Chinese medicinal herb paste for fractures and preparation thereof |
| CN107638486A (en) * | 2017-08-30 | 2018-01-30 | 张�林 | A kind of Chinese medicine medicine oil and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 万军梅，等: "风痛灵擦剂的毒理学研究", 《中国中医骨伤科杂志》 * |
| 黄玉娟，等: "复方铁箍散软膏、止痛散软膏治疗外科病1268例", 《陕西中医》 * |
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Application publication date: 20200211 |
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