CN110763854A - Sample introduction module - Google Patents

Sample introduction module Download PDF

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Publication number
CN110763854A
CN110763854A CN201911209195.XA CN201911209195A CN110763854A CN 110763854 A CN110763854 A CN 110763854A CN 201911209195 A CN201911209195 A CN 201911209195A CN 110763854 A CN110763854 A CN 110763854A
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CN
China
Prior art keywords
subassembly
sample
platform
bar code
bar
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Pending
Application number
CN201911209195.XA
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Chinese (zh)
Inventor
许国和
王远
赵勇
柳赛平
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Ningbo Purui Bai Biotechnology Ltd By Share Ltd
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Ningbo Purui Bai Biotechnology Ltd By Share Ltd
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Publication date
Application filed by Ningbo Purui Bai Biotechnology Ltd By Share Ltd filed Critical Ningbo Purui Bai Biotechnology Ltd By Share Ltd
Priority to CN201911209195.XA priority Critical patent/CN110763854A/en
Publication of CN110763854A publication Critical patent/CN110763854A/en
Pending legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302Apparatus specially adapted for immunological test procedures
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00722Communications; Identification
    • G01N35/00732Identification of carriers, materials or components in automatic analysers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/025Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a carousel or turntable for reaction cells or cuvettes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00722Communications; Identification
    • G01N35/00732Identification of carriers, materials or components in automatic analysers
    • G01N2035/00742Type of codes
    • G01N2035/00752Type of codes bar codes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027General features of the devices

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The invention relates to the technical field of protein immunodetection analyzers, in particular to a sample injection module. This advance kind module includes sample cell, a plurality of bar sample frame, advances kind platform, advances kind subassembly, goes out kind platform, goes out kind subassembly, sample cell and compresses tightly subassembly, bar code appearance and translation subassembly, be provided with 10 sample cell on the bar sample frame, the sample cell is placed sample cell inslot portion, it sets up to advance kind subassembly the below of kind platform, it sets up to go out kind subassembly the lower part of kind platform, translation subassembly sets up advance kind platform and go out on the same horizontal plane of kind platform, the bar code appearance sets up the top of translation subassembly.

Description

Sample introduction module
Technical Field
The invention relates to the technical field of protein immunodetection analyzers, in particular to a sample injection module.
Background
In general protein detection instruments on the market, functions such as transportation of a sample rack and horizontal bidirectional translation of the sample rack are generally not provided, so that more time is wasted in continuous work of equipment, and the working efficiency is low.
Disclosure of Invention
The invention provides a sample introduction module which has the advantages of simple structure, convenient use and longer service life, and can effectively stack and carry sample racks and equip reaction cups.
The invention is realized by the following technical scheme:
advance kind module, including reaction cup, a plurality of bar sample frame, advance kind platform, advance kind subassembly, go out kind platform, go out kind subassembly, reaction cup and compress tightly subassembly, bar code appearance and translation subassembly, be provided with 10 reaction cup grooves on the bar sample frame, the reaction cup is placed reaction cup inslot portion, it sets up to advance kind the subassembly the below of advancing kind platform, it sets up to go out kind the subassembly go out the lower part of kind platform, the translation subassembly sets up advance kind platform and go out on the same horizontal plane of kind platform, the bar code appearance sets up the top of translation subassembly.
As preferred the translation subassembly includes a set of synchronous machine, two driving belt, two axis of rotation and a plurality of fixture block, the fixture block sets up on the driving belt, bar sample frame card is in between the fixture block to two driving belt set up in step, the driving belt cover is in on the axis of rotation, the axis of rotation is connected through rotating the belt on the synchronous machine, advance the kind subassembly and set up go out the right side of appearance subassembly, the translation subassembly drives bar sample frame is from the right side to left side motion, advance the kind subassembly and promote bar sample frame inward movement, it promotes to go out the kind subassembly bar sample frame outward movement.
Preferably, the bar sample shelf is provided with 10 bar code gaps, through the bar code gap, the bar code appearance can discern bar code on the reaction cup, the reaction cup compresses tightly the top that the subassembly set up at the removal subassembly, the reaction cup compresses tightly the subassembly and includes backup pad, lifter and hold-down head, the backup pad sets up advance kind between the platform and the appearance platform, the lifter is connected in on the backup pad, the hold-down head is connected on the lifter.
The beneficial effects brought by the invention are as follows:
compared with the prior art, the strip-shaped sample rack has the advantages that the strip-shaped sample rack is placed and transported through the design of the sample feeding assembly and the sample discharging assembly, the sample tubes are firmer on the strip-shaped sample rack through the design of the pressing assembly, the sample tubes can be punctured for the sample tubes, and meanwhile, 5 strip-shaped sample racks can be assembled on the sample feeding platform and the sample discharging platform simultaneously, so that continuous sample feeding and sample discharging can be realized.
Drawings
The present invention will be described in further detail with reference to the accompanying drawings.
FIG. 1 is a schematic diagram of the structure of a specific protein analyzer according to the present invention.
FIG. 2 is an external view of a specific protein analyzer according to the present invention.
Fig. 3 is a schematic structural diagram of the sample injection module of the present invention.
FIG. 4 is a schematic structural diagram of the reagent disk of the present invention.
FIG. 5 is a top view of a reagent disk according to the present invention.
FIG. 6 is a side view of a reagent disk according to the present invention.
Fig. 7 is a schematic structural diagram of the arm assembly according to the present invention.
FIG. 8 is a schematic structural view of a reaction disk according to the present invention.
FIG. 9 is a side view of a reaction tray according to the present invention.
The corresponding reference numbers for the component names in the figures are as follows:
1. a frame; 2. a housing; 3. a touch screen display; 4. a sample introduction module; 5. a reagent tray; 6. a mechanical arm group; 7. a reaction disc; 8. a middle partition plate; 9. a reaction cup; 10. a strip-shaped sample holder; 11. a sample introduction platform; 12. a sample introduction assembly; 13. a sample outlet platform; 14. a sample outlet assembly; 16. a bar code instrument; 17. a translation assembly; 18. a reaction cup groove; 19. a stainless steel pan body; 20. a fan-shaped reagent rack; 21. a rotating assembly; 22. a first motor; 23. a refrigeration module; 24. a bar code instrument; 25. an air duct; 26. an arm group base; 27. a lifting arm; 28. a lifting motor; 29. rotating the motor; 30. an anti-collision assembly; 31. a stirring and cleaning component; 32. a second motor; 36. a reaction bin; 38. a turntable panel; 43. a turntable cover plate; 44. a synchronous motor; 45. a drive belt; 46. a rotating shaft; 47. a clamping block; 48. rotating the belt; 49. a bar code gap; 50. a support plate; 51. a lifting rod; 52. a compression head; 53. a barcode instrument window; 54. transparent glass; 55. a fan; 56. a sliding rail; 57. a slider; 58. a rotating assembly; 59. lifting the slide rail; 60. a sampling needle.
Detailed Description
The invention is described in further detail below with reference to the following figures and examples:
as an embodiment of the sample introduction module of the present invention, as shown in fig. 1 to 9, the sample introduction module includes a rack 1, a housing 2, a touch screen display 3, a sample introduction module 4, a reagent disk 5, a mechanical arm group 6, and a reaction disk 7, wherein the sample introduction module 4, the reagent disk 5, the mechanical arm group 6, and the reaction disk 7 are disposed inside the rack 1, the housing 2 is wrapped outside the rack 1, the touch screen display 3 is connected to the right side of the housing 2, a middle partition plate 8 is disposed in the middle of the rack 1, the reaction disk 7 and the mechanical arm group 6 are disposed on the middle partition plate 8, and the middle of the reagent disk 5 passes through the middle partition plate 8.
In this embodiment, advance kind module 4 and connect in the front portion of frame 1, including reaction cup 9, a plurality of bar sample frame 10, advance kind platform 11, advance kind subassembly 12, go out kind platform 13, go out kind subassembly 14, reaction cup and compress tightly subassembly, bar code appearance 16 and translation subassembly 17, be provided with 10 reaction cup grooves 18 on the bar sample frame 10, reaction cup 9 is placed reaction cup groove 18 is inside, it sets up to advance kind subassembly 12 advance the below of kind platform 11, it sets up to go out kind subassembly 14 go out the lower part of kind platform 13, translation subassembly 17 sets up advance kind platform 11 and the same horizontal plane of a kind platform 13, bar code appearance 16 sets up translation subassembly 17's top.
In this embodiment, the reagent tray 5 includes a stainless steel pot 19, 16 fan-shaped reagent racks 20, a rotating assembly 21, a first motor 22, a refrigeration module 23, a barcode meter 24, and an air duct 25, the stainless steel pot 19, the fan-shaped reagent racks 20, the rotating assembly 21, the barcode meter 24, and the refrigeration module 23 are disposed on the upper portion of the middle partition plate 8, and the air duct 25 and the first motor 22 are disposed on the lower portion of the middle partition plate 8.
In this embodiment, the robot arm assembly 6 includes an arm assembly base 26, a lifting arm 27, a lifting motor 28, a rotating motor 29, a collision avoidance module 30, and a stirring and cleaning module 31, wherein the lifting arm 27 is installed on the arm assembly base 26, the lifting motor 28 and the rotating motor 29 are installed on the side surface of the arm assembly base 26, the collision avoidance module 30 is installed on the upper portion of the lifting arm 27, and the stirring and cleaning module 31 is installed on the lower portion of the lifting arm 27.
In this embodiment, the reaction disk 7 includes a second motor 32, a turntable support shaft (not shown), a transmission module (not shown), a heating temperature control module (not shown), a reaction chamber 36, a turntable support (not shown), a turntable panel 38, and an induction counting module (not shown), the turntable panel 38 is annular and has a plurality of slots (not shown) formed thereon, each reaction cup is inserted into the slots (not shown) from top to bottom, the second motor 32 is disposed on the bottom plate and connected to the turntable support (not shown) through the transmission module (not shown) to drive the heating temperature control module (not shown) and the turntable panel 38 fixed on the turntable support (not shown) to rotate, an opening at an upper end of the turntable support (not shown) is sealed by a turntable cover plate 43, the second motor 32 is electrically connected to the main control board.
In this embodiment, translation subassembly 17 includes a set of synchronous machine 44, two driving belt 45, two axis of rotation 46 and a plurality of fixture block 47, fixture block 47 sets up on the driving belt 45, bar sample frame 10 card is in between the fixture block 47 to two driving belt 45 set up in step, driving belt 45 overlaps on the axis of rotation 46, axis of rotation 46 is connected through rotating belt 48 on the synchronous machine 44, advance kind subassembly 12 and set up out the right side of appearance subassembly 14, translation subassembly 17 drives bar sample frame 10 is from the right side to the left motion, advance kind subassembly 12 and promote bar sample frame 10 inward movement, it promotes to go out appearance subassembly 14 bar sample frame 10 outward movement.
In this embodiment, bar sample frame 10 is provided with 10 bar code gaps 49, through bar code gap 49, bar code appearance 16 can discern bar code on the reaction cup 9, the reaction cup compresses tightly the top that the subassembly set up at removal subassembly 17, the reaction cup compresses tightly the subassembly and includes backup pad 50, lifter 51 and pressure head 52, bracing piece 50 is connected on advancing kind platform 11 and the appearance platform 13, lifter 51 is connected above backup pad 50, pressure head 52 is connected on the lifter 51.
In this embodiment, the fan-shaped reagent rack 20, the rotating assembly 21 and the refrigerating module 23 are disposed inside the stainless steel pot 19, the barcode instrument 24 is disposed beside the stainless steel pot 19, the air duct 25 is connected to the lower portion of the stainless steel pot 19, the rotating assembly 21 is connected to the first motor 22 in a transmission manner, the fan-shaped reagent rack 20 is sleeved on the rotating assembly 21, a barcode instrument window 53 is disposed on the side wall of the stainless steel pot 19, a transparent glass 54 is mounted on the barcode instrument window 53, the barcode instrument 24 identifies a barcode on the fan-shaped reagent rack 20 through the transparent glass 54, a heating module (not shown in the figure) is disposed on the barcode instrument window 53, the heating module (not shown in the figure) heats the transparent glass 54, the refrigerating module 23 is mounted at the bottom of the fan-shaped reagent rack 20, an air inlet of the air duct 25 is connected to the bottom of the stainless steel pot body 19, and an air outlet of the air duct 25 is provided with a fan 55.
In this embodiment, the arm group base 26 is installed on the middle partition plate 8, the inside of the arm group base 26 is provided with an optical axis 56, a sliding block 57 is connected to the optical axis 56, the lifting arm 27 is connected to the upper portion of the sliding block 57, the sliding block 57 is connected to the upper portion of the lifting motor 28 through a belt, the lifting arm 27 and the sliding block 57 are installed with a rotating component 58 therebetween, the rotating component 28 is connected to the upper portion of the rotating motor 29 through a belt, the lifting arm 27 is provided with a lifting slide rail 59 and a sampling needle 60 thereon, the stirring and cleaning component 31 is sleeved to the lifting slide rail 59, and the anti-collision component 30 is disposed near the top end of the sampling needle 60.
The basic principles and the main features of the invention and the advantages of the invention have been shown and described above, it being obvious to a person skilled in the art that the invention is not limited to the details of the above-described exemplary embodiments.
The present invention may be embodied in other specific forms without departing from its spirit or essential characteristics. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.

Claims (3)

1. The utility model provides a kind module of advancing, its characterized in that includes reaction cup, a plurality of bar sample frame, advances a kind platform, advances a kind subassembly, goes out a kind platform, goes out a kind subassembly, reaction cup and compresses tightly subassembly, bar code appearance and translation subassembly, be provided with 10 reaction cup grooves on the bar sample frame, the reaction cup is placed reaction cup inslot portion, advance a kind subassembly and set up advance the below of kind platform, it sets up to go out a kind subassembly go out the lower part of kind platform, translation subassembly sets up advance kind platform and go out on the same horizontal plane of kind platform, the bar code appearance sets up the top of translation subassembly.
2. The sample feeding module according to claim 1, wherein the translation assembly comprises a set of synchronous motor, two transmission belts, two rotation shafts and a plurality of clamping blocks, the clamping blocks are disposed on the transmission belts, the strip-shaped sample rack is clamped between the clamping blocks, the two transmission belts are disposed synchronously, the transmission belts are sleeved on the rotation shafts, the rotation shafts are connected on the synchronous motor through rotation belts, the sample feeding assembly is disposed on the right side of the sample feeding assembly, the translation assembly drives the strip-shaped sample rack to move from right to left, the sample feeding assembly pushes the strip-shaped sample rack to move inwards, and the sample feeding assembly pushes the strip-shaped sample rack to move outwards.
3. The sample introduction module according to claim 2, wherein the bar-shaped sample rack is provided with 10 bar code gaps, the bar code instrument can identify a bar code on the cuvette through the bar code gaps, the cuvette pressing assembly is disposed above the moving assembly, the cuvette pressing assembly comprises a support plate, a lifting rod and a pressing head, the support plate is disposed between the sample introduction platform and the sample discharge platform, the lifting rod is connected to the support plate, and the pressing head is connected to the lifting rod.
CN201911209195.XA 2019-11-30 2019-11-30 Sample introduction module Pending CN110763854A (en)

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CN201911209195.XA CN110763854A (en) 2019-11-30 2019-11-30 Sample introduction module

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Application Number Priority Date Filing Date Title
CN201911209195.XA CN110763854A (en) 2019-11-30 2019-11-30 Sample introduction module

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CN110763854A true CN110763854A (en) 2020-02-07

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023102547A1 (en) * 2021-12-03 2023-06-08 Beckman Coulter, Inc. Window defogger for sample preparation system

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105388314A (en) * 2015-12-17 2016-03-09 嘉兴凯实生物科技有限公司 Fully automated sample adding instrument
CN105929184A (en) * 2016-06-30 2016-09-07 嘉兴凯实生物科技有限公司 Full-automatic luminescence immunity analyzer
CN205844341U (en) * 2016-06-30 2016-12-28 嘉兴凯实生物科技有限公司 A kind of full-automatic illumination immunity analysis instrument
CN110297101A (en) * 2019-07-30 2019-10-01 南京岚煜生物科技有限公司 The method of the automatic sample machine and automatic sample of sample adding device and pipeline system detection
CN211179864U (en) * 2019-11-29 2020-08-04 宁波普瑞柏生物技术股份有限公司 Specific protein analyzer

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105388314A (en) * 2015-12-17 2016-03-09 嘉兴凯实生物科技有限公司 Fully automated sample adding instrument
CN105929184A (en) * 2016-06-30 2016-09-07 嘉兴凯实生物科技有限公司 Full-automatic luminescence immunity analyzer
CN205844341U (en) * 2016-06-30 2016-12-28 嘉兴凯实生物科技有限公司 A kind of full-automatic illumination immunity analysis instrument
CN110297101A (en) * 2019-07-30 2019-10-01 南京岚煜生物科技有限公司 The method of the automatic sample machine and automatic sample of sample adding device and pipeline system detection
CN211179864U (en) * 2019-11-29 2020-08-04 宁波普瑞柏生物技术股份有限公司 Specific protein analyzer

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023102547A1 (en) * 2021-12-03 2023-06-08 Beckman Coulter, Inc. Window defogger for sample preparation system

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