CN110755308A - Anti-aging medical biological repair dressing containing traditional Chinese medicines and preparation method thereof - Google Patents
Anti-aging medical biological repair dressing containing traditional Chinese medicines and preparation method thereof Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/004—Aftersun preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
Abstract
The invention discloses an anti-aging medical biological repair dressing containing traditional Chinese medicines and a preparation method thereof, wherein the dressing comprises lucid ganoderma, poria cocos, mulberry leaves, common perilla, ginkgo kernels, tribulus terrestris, bletilla striata and white chrysanthemum. The anti-aging medical biological repair dressing containing traditional Chinese medicines provided by the invention has three effects of professional biological whitening, skin repair and moisturizing, is simple and effective in formula, clear in component effect and action mechanism, strong in pertinence and speciality and high in safety, and fills up the blank of professional medical anti-aging medical biological repair dressing products.
Description
Technical Field
The invention belongs to the technical field of medical materials, and particularly relates to an anti-aging medical biological repair dressing containing traditional Chinese medicines and a preparation method thereof.
Background
Aging is a direct manifestation of the slowing of the human body, and is also a natural process, and the reason of aging mainly comprises the following aspects: excessive oxidation, cell life, protein aging, endocrine hypofunction, microcirculation disturbance, hormone deficiency, etc.
Skin aging refers to the aging damage of skin function, which reduces the protection ability and regulation ability of skin to human body, so that the skin can not adapt to the change of internal and external environment, and the change of overall appearance conditions such as color, luster, shape, texture, etc. appears. Aging of the skin is classified into intrinsic aging and extrinsic aging. Endogenous aging refers to natural aging of the skin with aging, which is manifested by whitening of the skin, appearance of fine wrinkles, decreased elasticity, skin laxity, etc. Exogenous aging refers to aging caused by environmental factors such as ultraviolet radiation, smoking, wind, sun, and exposure to harmful chemicals.
Common skin anti-aging methods are: moisturizing, repairing skin, removing wrinkles, preventing sunburn, cleaning, controlling oil, reasonably diet, massaging, resisting aging, etc.
Currently, masks are the most effective anti-aging products in anti-aging skin care products, and their function is to soak a milk bath on the face's skin, which can soothe the skin and allow the skin to better absorb anti-aging ingredients in a relaxed state.
At present, most of facial masks have the conventional effects of resisting aging, replenishing water, whitening and the like, but lack the treatment effects of repairing skin wounds, recovering the luster and elasticity of skin, shrinking pores, lightening wrinkles and the like.
In the field of medical repairing masks, enterprises in China take various traditional Chinese medicine extracts as additives, and add the additives into common masks to produce products such as medical masks (or medical repairing masks and medical repairing pastes) and the like as upgrading products of traditional masks. However, the products mainly play a role in moisturizing, and basically have no anti-aging and skin repairing functions.
Therefore, in the market, medical-grade skin care products with anti-aging efficacy and repairing efficacy are blank, and medical-grade anti-aging medical biological repairing dressing products with three efficacies of professional biological anti-aging, skin repairing and moisturizing are not available.
Disclosure of Invention
One of the purposes of the invention is to provide an anti-aging medical biological repair dressing containing traditional Chinese medicines;
the invention also aims to provide a preparation method of the anti-aging medical biological repair dressing containing traditional Chinese medicines.
In order to achieve the purpose, the invention adopts the technical scheme that:
an anti-aging medical biological repair dressing containing traditional Chinese medicines comprises the following raw materials in parts by weight: 5-10 parts of lucid ganoderma, 10-15 parts of poria cocos, 5-10 parts of mulberry leaves, 3-10 parts of common perilla, 6-10 parts of ginkgo kernels, 6-10 parts of tribulus terrestris, 3-10 parts of bletilla striata, 5-10 parts of white chrysanthemum, 0.1-0.5 part of sodium hyaluronate, 3-6 parts of glycerol and auxiliary materials.
In order to further realize the invention, the dressing is repair quick-cleaning water gel, and the auxiliary materials of the dressing are composed of the following raw materials in parts by weight: 100-150 parts of deionized water, 1-3 parts of vitamin E, 1-3 parts of amino acid, 1-5 parts of hydrolyzed collagen, 6-10 parts of sodium laureth sulfate, 1-2 parts of acetylated hexapeptide, 1-3 parts of ursolic acid, 2-5 parts of human-like collagen, 3-8 parts of lecithin and 3-5 parts of xanthan gum.
In order to further realize the invention, the dressing is skin care spray, and the auxiliary materials of the dressing are composed of the following raw materials in parts by weight: 100 portions of deionized water, 150 portions of vitamin E, 0.5 to 1 portion of amino acid, 0.5 to 1 portion of hydrolyzed collagen, 1 to 3 portions of sodium laureth sulfate, 0.5 to 1 portion of acetylated hexapeptide, 0.5 to 2 portions of ursolic acid and 1 to 2 portions of human-like collagen.
In order to further realize the invention, the dressing is repair and maintenance ice water, repair and maintenance ice liquid or repair and maintenance ice cream, and the auxiliary material of the dressing is composed of the following raw materials in parts by weight: 100-150 parts of deionized water, 1-3 parts of vitamin E, 1-3 parts of amino acid, 1-5 parts of hydrolyzed collagen, 1-2 parts of acetylated hexapeptide, 1-3 parts of ursolic acid and 2-5 parts of human-like collagen.
In order to further realize the invention, the dressing is repairing and maintaining ice cream, and the auxiliary materials of the dressing comprise the following raw materials in parts by weight: 100-150 parts of deionized water, 1-3 parts of vitamin E, 1-3 parts of amino acid, 1-5 parts of hydrolyzed collagen, 1-2 parts of acetylated hexapeptide, 1-3 parts of ursolic acid, 2-5 parts of human-like collagen, 6-9 parts of lecithin and 3-6 parts of xanthan gum.
In order to further realize the invention, the dressing is a repairing and nourishing gel, and the auxiliary materials of the dressing are composed of the following raw materials in parts by weight: 100-150 parts of deionized water, 1-3 parts of vitamin E, 1-3 parts of amino acid, 1-5 parts of hydrolyzed collagen, 1-2 parts of acetylated hexapeptide, 1-3 parts of ursolic acid, 2-5 parts of human-like collagen, 9-12 parts of lecithin and 6-10 parts of xanthan gum.
In order to further realize the invention, the dressing is a repairing nourishing paste, and the auxiliary materials of the dressing are composed of the following raw materials in parts by weight: 100-150 parts of deionized water, 1-3 parts of vitamin E, 1-3 parts of amino acid, 1-5 parts of hydrolyzed collagen, 1-2 parts of acetylated hexapeptide, 1-3 parts of ursolic acid, 2-5 parts of human-like collagen, 10-15 parts of lecithin and 9-12 parts of xanthan gum.
A preparation method of an anti-aging medical biological repair dressing containing traditional Chinese medicines comprises the following steps:
(1) preparing Ganoderma, Poria, folium Mori, rhizoma Stachydis Japonicae, semen Ginkgo, fructus Atriplicis Sibiricae, rhizoma Bletillae and flos Chrysanthemi into nanometer Chinese medicinal powder mixture by nanometer Chinese medicinal powder preparation process;
(2) mixing the nanometer Chinese medicinal powder mixture obtained in step (1) with 10-25L deionized water by static boiling method, decocting for 45-100min, and cooling to 40-60 deg.C to obtain Chinese medicinal mixed concentrated solution;
(3) heating deionized water to 80-85 deg.C, adding sodium hyaluronate and glycerol, homogenizing, and keeping the temperature for 5-10min to obtain sodium hyaluronate mixture;
(4) and (3) cooling the sodium hyaluronate mixture obtained in the step (3) to 40-50 ℃, adding different amounts of the traditional Chinese medicine mixed concentrated solution obtained in the step (2) according to dosage forms, adding different auxiliary materials according to dosage forms, homogenizing, cooling to 38 ℃, standing until the solution is completely swelled, and thus obtaining the anti-aging medical biological repair dressing containing traditional Chinese medicines.
In order to further realize the invention, the Chinese medicinal mixed concentrated solution with different dosage is added according to the dosage form in the step (4):
respectively adding 20-40% of the traditional Chinese medicine mixed concentrated solution into the repairing quick-cleaning water gel and the repairing nourishing gel;
adding 5-10% of the Chinese medicinal concentrated solution into the skin care spray;
adding 40-60% of the traditional Chinese medicine mixed concentrated solution into the repair and maintenance ice water;
adding 60-80% of the Chinese medicinal concentrated solution into the repairing and maintaining ice liquid;
respectively adding 80-100% of the Chinese medicinal concentrated solution into the repairing and maintaining ice cream and the repairing and maintaining ice cream;
the repairing and nourishing cream is added with 100 percent of traditional Chinese medicine mixed concentrated solution.
Compared with the prior art, the invention has the beneficial effects that:
the main components of the anti-aging medical biological repair dressing containing traditional Chinese medicines provided by the invention comprise acetylated hexapeptide with anti-aging effect, ursolic acid and sodium hyaluronate, and also comprise a traditional Chinese medicine formula which has skin repair and anti-aging effects and is formed by compatibility of lucid ganoderma, poria cocos, mulberry leaves, common perilla, ginkgo kernels, tribulus terrestris, bletilla striata and white chrysanthemum, and no chemical preparation which is easy to cause skin reaction, such as hormone, antibiotic, heavy metal, alcohol, essence, pigment fluorescent agent, preservative and the like, is safe when being used by special people with poor skin resistance and no disinclination like the hormone.
Ganoderma lucidum: sweet, light and mild in nature and taste, enters liver, lung and kidney meridians, and has the effects of tonifying qi and nourishing blood, resisting free radicals, regulating metabolic balance and the like.
Tuckahoe, poria cocos: sweet, light and flat in nature and taste, enters lung, stomach and kidney channels, and has the effects of promoting diuresis, excreting dampness, invigorating spleen and calming heart, thereby moistening skin.
Mulberry leaf: has bitter, sweet and cold property, enters liver and lung channels, has good skin beautifying effect, and particularly has better curative effect on acne and brown spots on the face. It is combined with Poria to achieve the effects of increasing skin elasticity and repairing skin.
White perilla: is bitter in nature, sweet and warm in taste, and has the effects of tonifying qi and spleen, eliminating dampness and promoting diuresis, moistening skin and the like, and spleen and stomach meridians entered. It is combined with Poria to achieve the effects of moisturizing and nourishing water.
And (3) ginkgo kernel: bitter, sweet, astringent and neutral in nature and taste, enters lung meridian, and has the effects of delaying skin aging, preventing pachylosis and the like. It is combined with rhizoma Bletillae, and has effects of keeping moisture and resisting wrinkle.
Tribulus terrestris: bitter, pungent and mild in property and flavor, enters liver meridian and has obvious anti-aging effect.
Bletilla striata: bitter, sweet, astringent and slightly cold in nature and flavor, enters lung, liver and stomach meridians, and has the effects of locking water, moistening skin, improving skin microcirculation and promoting skin metabolism.
White chrysanthemum: bitter, sweet and slightly cold in nature and flavor, enters lung and liver meridians, and has the effects of removing swelling and pain, relieving itching, refreshing body, caring skin and beautifying. It is combined with folium Mori to restore skin and discharge toxin.
Deionized water: can better control the microorganisms and impurities of the product.
Sodium hyaluronate: can form a layer of air-permeable film on the surface of skin to make the skin smooth and moist, promote proliferation and differentiation of epidermal cells, remove oxygen free radicals, and promote regeneration of the skin at the injured part.
Vitamin E: can provide the skin with the functions of keeping the skin elasticity, supplementing water and improving and enhancing the elasticity of new cells.
Amino acids: has effects of activating cells, improving metabolism and blood circulation, and reviving skin.
Hydrolyzing collagen: has effects in supplementing collagen, restoring skin elasticity, restoring firmness, reducing sagging phenomenon, and smoothing fine lines and wrinkles.
Acetylated hexapeptides: also called wrinkle-removing peptide, has the functions of blocking the transmission speed of muscle nerve, inhibiting the generation of expression lines and fine wrinkles, fully regulating the physiological function of human body and effectively resisting aging.
Ursolic acid: has good antioxidant and moisture keeping effects.
Human-like collagen: has effects of keeping moisture, whitening skin, and improving skin aging such as wrinkle, speckle, and dryness due to collagen loss.
Sodium laureth sulfate: has foaming and cleaning effects, and is a common surfactant for skin care products.
Lecithin: the emulsifier, also known as lecithin, has the effect of providing sufficient nutrients such as water and oxygen to the skin to make the skin smooth and soft.
Xanthan gum: has effects in moisturizing skin and delaying skin aging, and can be used as viscosity regulator.
Glycerol: is a moisturizing factor indispensable to cells, has excellent capacity of regulating skin metabolism, promotes the activity of skin aquaporins, and assists in promoting skin metabolism and purification.
The traditional Chinese medicine formula and the additive fully consider six compatibility relations of mutual reinforcement, mutual induction, mutual incompatibility, mutual killing, mutual inhibition and reverse between the traditional Chinese medicine formula and the additive and effect differences generated under different dosage proportions of the traditional Chinese medicines and the additive according to the mechanisms of the traditional Chinese medicine science, the traditional Chinese medicine prescriptions and the traditional Chinese medicine pharmacology, optimize dosage and accurately prepare the traditional Chinese medicine formula and the additive, and carry out combination reaction on effective bioactive components dissolved out of the traditional Chinese medicines by mixing and decocting the traditional Chinese medicines by using deionized water through a static boiling method to form a more complex combination with a specific effect, generate a huge synergistic effect and greatly enhance the treatment effect, wherein the specific action mechanism is as follows:
ganoderma and Poria are used as main materials, and have effects in invigorating qi, nourishing blood, invigorating spleen, calming heart, and regulating metabolism balance; folium Mori, rhizoma Stachydis Japonicae, semen Ginkgo, fructus Atriplicis Sibiricae, white flos Chrysanthemi and fructus Tribuli can be used as adjuvant drugs for caring skin, removing speckle, supplementing water, keeping moisture, repairing skin, resisting wrinkle, promoting metabolism, and removing toxic substances; the main drug property is sweet, light and mild in taste, the auxiliary drug property is bitter, sweet, pungent and slightly cold, the main drug property and the auxiliary drug property are mutually incompatible, and the product is mild and has no stimulation; the tuckahoe and the common perilla mutually act to enhance the effects of moisturizing and preserving moisture; the tuckahoe and the mulberry leaf are mutually reinforced, so that the skin elasticity can be increased and the skin can be repaired; the gingko kernels and the bletilla striata are mutually matched, so that the metabolism of the skin can be promoted, moisture can be preserved, and wrinkles can be reduced; the anti-aging and skin repairing effects of the traditional Chinese medicine formula are in mutual reinforcement with the moisturizing effects of additives such as sodium hyaluronate and the like, and the moisturizing and skin elasticity increasing effects can be enhanced; the traditional Chinese medicine formula has the effects of benefiting qi, nourishing blood, moisturizing and resisting wrinkles, and the anti-aging effect of additives such as acetylated hexapeptide, ursolic acid, human-like collagen and the like are mutually matched, so that the anti-aging and moisturizing effects can be enhanced.
The traditional Chinese medicine formula adopted by the anti-aging medical biological repair dressing containing traditional Chinese medicines is prepared according to the traditional Chinese medicine science, the traditional Chinese medicine prescription science and the traditional Chinese medicine pharmacology mechanism, is simple and effective, has definite component effects and action mechanism, strong pertinence and specificity and high safety, has the treatment effects of tonifying qi and nourishing blood, resisting free radicals, regulating metabolic balance, promoting diuresis and excreting dampness, tonifying spleen and calming heart, moistening skin, increasing skin elasticity, repairing skin, eliminating dampness and promoting diuresis, preventing skin roughness, moisturizing and resisting wrinkles, locking water and moistening skin, improving skin microcirculation, discharging toxins and the like, is cooperated with additives with anti-aging effects such as acetylated hexapeptide, ursolic acid, sodium hyaluronate and the like, and also has the effects of moderating, eliminating fatigue, softening epidermal tissues, improving microcirculation, promoting skin metabolism, promoting proliferation and differentiation of epidermal cells, removing oxygen radicals, Promoting the regeneration of skin at the injured part, shrinking pores, reducing wrinkles, repairing damaged skin epidermal cells, deeply nourishing skin, recovering the luster and elasticity of skin, effectively slowing down allergy, inhibiting melanin formation, relieving skin, improving the dry state of skin, supplementing skin moisture, moisturizing skin and the like. The anti-aging medical biological repair dressing containing traditional Chinese medicines provided by the invention is matched with various products, and fills the blank that the current market has three effects of professional biological anti-aging, skin repair and moisturizing, and a professional medical anti-aging medical biological repair dressing product.
According to the experimental results of the examples, the anti-aging medical biological repair dressing containing traditional Chinese medicines has the following treatment effects: 1. compared with the common anti-aging skin care product which does not contain traditional Chinese medicines in the existing product, the anti-aging medical biological repair dressing containing traditional Chinese medicines has the advantage that the anti-aging treatment effect is increased; 2. compared with the common anti-aging skin care product which does not contain traditional Chinese medicines in the existing product, the anti-aging medical biological repair dressing containing traditional Chinese medicines provided by the invention has the advantage that the treatment effect of skin repair is increased; 3. compared with the common anti-aging skin care product which does not contain traditional Chinese medicines in the existing product, the anti-aging medical biological repair dressing containing traditional Chinese medicines enhances the effects of moisturizing and treating the skin; 4. compared with two anti-aging medical biological repair dressings containing traditional Chinese medicines and used for adjusting the dosage of the mixed concentrated solution of the traditional Chinese medicine formula, the anti-aging medical biological repair dressing containing traditional Chinese medicines prepared according to the traditional Chinese medicine formula provided by the invention has the best treatment effects of anti-aging, skin repair and moisturizing; 5. compared with the common anti-aging skin care product containing other traditional Chinese medicines in the existing product, the anti-aging medical biological repair dressing containing the traditional Chinese medicines prepared according to the traditional Chinese medicine formula provided by the invention has the best treatment effects of anti-aging, skin repair and water replenishing and moisture preserving.
The anti-aging medical biological repair dressing containing traditional Chinese medicines provided by the invention has three effects of professional biological anti-aging, skin repair and moisturizing, is simple and effective in formula, clear in component effect and action mechanism, strong in pertinence and speciality and high in safety, and fills up the blank of professional medical anti-aging medical biological repair dressing products.
Detailed Description
The present invention will be further described with reference to the following embodiments.
Example 1:
(1) preparing 10g of lucid ganoderma, 15g of poria cocos, 10g of mulberry leaves, 10g of common perilla, 10g of ginkgo kernels, 10g of tribulus terrestris, 10g of bletilla striata and 10g of white chrysanthemum into a nano traditional Chinese medicine powder mixing material by adopting a nano traditional Chinese medicine powder preparation process;
(2) mixing the nanometer Chinese medicinal powder mixture obtained in step (1) with 25L deionized water by static boiling method, decocting for 100min, and cooling to 60 deg.C to obtain Chinese medicinal mixed concentrated solution;
(3) heating 150g of deionized water to 85 ℃, adding 0.5g of sodium hyaluronate and 6g of glycerol, homogenizing uniformly, and keeping the temperature for 10min to obtain a sodium hyaluronate mixture;
(4) cooling the sodium hyaluronate mixture obtained in the step (3) to 50 ℃, and adding different amounts of the traditional Chinese medicine mixed concentrated solution obtained in the step (2) according to dosage forms, wherein:
respectively adding 40% of traditional Chinese medicine mixed concentrated solution into the repairing quick-cleaning water gel and the repairing nourishing gel;
adding 10% of traditional Chinese medicine mixed concentrated solution into the skin care spray;
adding 60% of the traditional Chinese medicine mixed concentrated solution into the repair and maintenance ice water;
adding 80% of the traditional Chinese medicine mixed concentrated solution into the repairing and maintaining ice liquid;
adding 100% of the Chinese medicinal concentrated solution into the repairing and maintaining ice cream and the repairing and maintaining ice cream respectively;
adding 100% of the traditional Chinese medicine mixed concentrated solution into the repairing and nourishing paste;
then adding different auxiliary materials according to the dosage form, wherein:
adding vitamin E3g, 3g of amino acid, 5g of hydrolyzed collagen, 10g of sodium laureth sulfate, 2g of acetylated hexapeptide, 3g of ursolic acid, 5g of human-like collagen, 8g of lecithin and 5g of xanthan gum into the repairing quick-cleaning water gel;
vitamin E1g, amino acid 1g, hydrolyzed collagen 1g, sodium laureth sulfate 3g, acetylated hexapeptide 1g, ursolic acid 2g and human-like collagen 2g are added into the skin care spray;
vitamin E1g, amino acid 1g, hydrolyzed collagen 1g, acetylated hexapeptide 2g, ursolic acid 3g and human-like collagen 5g are added into the repairing and maintaining ice water;
adding vitamin E3g, 3g of amino acid, 5g of hydrolyzed collagen, 2g of acetylated hexapeptide, 3g of ursolic acid and 5g of human-like collagen into the repairing and maintaining ice liquid;
the repairing and maintaining ice cream is added with vitamin E3g, 3g of amino acid, 5g of hydrolyzed collagen, 2g of acetylated hexapeptide, 3g of ursolic acid and 5g of human-like collagen;
vitamin E3g, 3g of amino acid, 5g of hydrolyzed collagen, 2g of acetylated hexapeptide, 3g of ursolic acid, 5g of human-like collagen, 9g of lecithin and 6g of xanthan gum are added into the repairing and maintaining ice milk;
adding vitamin E3g, 3g of amino acid, 5g of hydrolyzed collagen, 2g of acetylated hexapeptide, 3g of ursolic acid, 5g of human-like collagen, 12g of lecithin and 10g of xanthan gum into the repairing and nourishing gel;
vitamin E3g, 3g of amino acid, 5g of hydrolyzed collagen, 2g of acetylated hexapeptide, 3g of ursolic acid, 5g of human-like collagen, 15g of lecithin and 12g of xanthan gum are added into the repairing and nourishing cream;
homogenizing, cooling to 38 deg.C, standing until the solution is completely swelled to obtain the anti-aging medical biological repair dressing containing traditional Chinese medicines.
Example 2:
(1) preparing 8g of lucid ganoderma, 12g of poria cocos, 8g of mulberry leaves, 6g of common perilla, 8g of ginkgo kernels, 8g of tribulus terrestris, 6g of bletilla striata and 8g of white chrysanthemum into a nano traditional Chinese medicine powder mixing material by adopting a nano traditional Chinese medicine powder preparation process;
(2) mixing the nanometer Chinese medicine powder mixed material in the step (1) with 18L deionized water by adopting a static boiling method, decocting for 60min, and cooling to 45 ℃ to obtain a Chinese medicine mixed concentrated solution;
(3) heating 120g of deionized water to 82 ℃, adding 0.3g of sodium hyaluronate and 5g of glycerol, homogenizing uniformly, and keeping the temperature for 8min to obtain a sodium hyaluronate mixture;
(4) cooling the sodium hyaluronate mixture obtained in the step (3) to 45 ℃, and adding different amounts of the traditional Chinese medicine mixed concentrated solution obtained in the step (2) according to dosage forms, wherein:
respectively adding 30% of traditional Chinese medicine mixed concentrated solution into the repairing quick-cleaning water gel and the repairing nourishing gel;
adding 8% of traditional Chinese medicine mixed concentrated solution into the skin care spray;
adding 50% of the traditional Chinese medicine mixed concentrated solution into the repair and maintenance ice water;
adding 70% of the traditional Chinese medicine mixed concentrated solution into the repairing and maintaining ice liquid;
respectively adding 90% of the traditional Chinese medicine mixed concentrated solution into the repairing and maintaining ice cream and the repairing and maintaining ice cream;
adding 100% of the traditional Chinese medicine mixed concentrated solution into the repairing and nourishing paste;
then adding different auxiliary materials according to the dosage form, wherein:
adding vitamin E2g, amino acid 2g, hydrolyzed collagen 3g, sodium laureth sulfate 8g, acetylated hexapeptide 1.5g, ursolic acid 2g, human-like collagen 4g, lecithin 6g and xanthan gum 4g into the repairing quick-cleaning water gel;
vitamin E0.8g, amino acid 0.8g, hydrolyzed collagen 0.8g, sodium laureth sulfate 2g, acetylated hexapeptide 0.8g, ursolic acid 1g and human-like collagen 1.5g are added into the skin care spray;
vitamin E2g, 2g of amino acid, 3g of hydrolyzed collagen, 1.5g of acetylated hexapeptide, 2g of ursolic acid and 4g of human-like collagen are added into the repairing and maintaining ice water;
adding vitamin E2g, amino acid 2g, hydrolyzed collagen 3g, acetylated hexapeptide 1.5g, ursolic acid 2g and human-like collagen 4g into the repairing and maintaining ice liquid;
the repairing and maintaining ice cream is added with vitamin E2g, 2g of amino acid, 3g of hydrolyzed collagen, 1.5g of acetylated hexapeptide, 2g of ursolic acid and 4g of human-like collagen;
vitamin E2g, amino acid 2g, hydrolyzed collagen 3g, acetylated hexapeptide 1.5g, ursolic acid 2g, human-like collagen 4g, lecithin 7g and xanthan gum 4g are added into the repairing and maintaining ice milk;
and vitamin E2g, amino acid 2g, hydrolyzed collagen 3g, acetylated hexapeptide 1.5g, ursolic acid 2g, human-like collagen 4g, lecithin 10g and xanthan gum 8g are added into the repairing and nourishing gel;
vitamin E2g, amino acid 2g, hydrolyzed collagen 3g, lecithin 12g and xanthan gum 10g are added into the repairing and nourishing cream;
homogenizing, cooling to 38 deg.C, standing until the solution is completely swelled to obtain the anti-aging medical biological repair dressing containing traditional Chinese medicines.
Example 3:
(1) preparing 5g of lucid ganoderma, 10g of poria cocos, 5g of mulberry leaves, 3g of common perilla, 6g of ginkgo kernels, 6g of tribulus terrestris, 3g of bletilla striata and 5g of white chrysanthemum into a nano traditional Chinese medicine powder mixing material by adopting a nano traditional Chinese medicine powder preparation process;
(2) mixing the nanometer Chinese medicinal powder mixture obtained in step (1) with 10L deionized water by static boiling method, decocting for 45min, and cooling to 40 deg.C to obtain Chinese medicinal mixed concentrated solution;
(3) heating 100g of deionized water to 80 ℃, adding 0.1g of sodium hyaluronate and 3g of glycerol, homogenizing uniformly, and keeping the temperature for 5min to obtain a sodium hyaluronate mixture;
(4) cooling the sodium hyaluronate mixture obtained in the step (3) to 40 ℃, and adding different amounts of the traditional Chinese medicine mixed concentrated solution obtained in the step (2) according to dosage forms, wherein:
respectively adding 20% of the traditional Chinese medicine mixed concentrated solution into the repairing quick-cleaning water gel and the repairing nourishing gel;
adding 5% of traditional Chinese medicine mixed concentrated solution into skin care spray;
adding 40% of the traditional Chinese medicine mixed concentrated solution into the repair and maintenance ice water;
adding 60% of the traditional Chinese medicine mixed concentrated solution into the repairing and maintaining ice liquid;
respectively adding 80% of the Chinese medicinal concentrated solution into the repairing and maintaining ice cream and the repairing and maintaining ice cream;
adding 100% of the traditional Chinese medicine mixed concentrated solution into the repairing and nourishing paste;
then adding different auxiliary materials according to the dosage form, wherein:
adding vitamin E1g, amino acid 1g, hydrolyzed collagen 1g, sodium laureth sulfate 6g, acetylated hexapeptide 1g, ursolic acid 1g, human-like collagen 2g, lecithin 3g and xanthan gum 3g into the repairing quick-cleaning water gel;
vitamin E0.5g, amino acid 0.5g, hydrolyzed collagen 0.5g, sodium laureth sulfate 1g, acetylated hexapeptide 0.5g, ursolic acid 0.5g and human-like collagen 1g are added into the skin care spray;
vitamin E1g, amino acid 1g, hydrolyzed collagen 1g, acetylated hexapeptide 1g, ursolic acid 1g and human-like collagen 2g are added into the repairing and maintaining ice water;
adding vitamin E1g, amino acid 1g, hydrolyzed collagen 1g, acetylated hexapeptide 1g, ursolic acid 1g and human-like collagen 2g into the repairing and maintaining ice liquid;
the repairing and maintaining ice cream is added with vitamin E1g, 1g of amino acid, 1g of hydrolyzed collagen, 1g of acetylated hexapeptide, 1g of ursolic acid and 2g of human-like collagen;
and vitamin E1g, amino acid 1g, hydrolyzed collagen 1g, acetylated hexapeptide 1g, ursolic acid 1g, human-like collagen 2g, lecithin 6g and xanthan gum 3g are added into the repairing and maintaining ice milk;
and vitamin E1g, amino acid 1g, hydrolyzed collagen 1g, acetylated hexapeptide 1g, ursolic acid 1g, human-like collagen 2g, lecithin 9g and xanthan gum 6g are added into the repairing and nourishing gel;
vitamin E1g, amino acid 1g, hydrolyzed collagen 1g, acetylated hexapeptide 1g, ursolic acid 1g, human-like collagen 2g, lecithin 10g and xanthan gum 9g are added into the repairing and nourishing cream;
homogenizing, cooling to 38 deg.C, standing until the solution is completely swelled to obtain the anti-aging medical biological repair dressing containing traditional Chinese medicines.
Experimental example 1:
(1) comparative experiment for scald repair of white rat: taking 25 white rats with the weight of about 110g, carrying out back unhairing treatment by using 6.5% sodium sulfide solution, wherein the unhairing area is 2.5cm multiplied by 2.0cm, and normally feeding the white rats for 12h after being washed clean by deionized water. The wounds were cut along the depilated site with a laser beam after anaesthesia with ether at a cutting rate of 0.5m/min, resulting in post-operative wounds which were then randomly divided into five groups of 5 per group. Then, the repair quick-cleaning gel (cleansing lotion), the repair refreshing spray (toner), the repair and maintenance ice liquid (essence), the repair and maintenance gel (repair lotion) and the repair and maintenance cream (cream) prepared by the formulation and the preparation method of example 1 were applied in the order of application, and were replaced every 2 hours, up to 10 times, with scab as a healing judgment condition and scab time as a comparative index, and the experimental results are shown in table 1.
(2) Anti-aging and moisturizing treatment contrast experiment: 25 female volunteers with history of hyaluronic acid injection and facial rigidity symptoms are collected, the female volunteers are aged 35-40 years, have the weight of 45-55kg, have no other facial skin diseases, have similar skin elasticity values and skin water content, and are randomly divided into five groups of 5 persons in each group. Then, the repair quick-cleaning gel (face cleaning lotion), the repair refreshing spray (toner), the repair and maintenance ice liquid (essence), the repair and maintenance gel (repair lotion) and the repair and maintenance cream (face cream) prepared by the formula and the preparation method of the embodiment 1 are coated in the coating sequence, the operation is carried out 2 times in the morning and at the evening every day for 5 days in total, the moisture indexes of the face skin before and after the experiment and the indexes reflecting the skin age are detected and recorded by a skin detector, and the average value of each group calculated on the same day is used as a comparison index. The tested volunteers apply the anti-aging medical biological repair dressing containing the traditional Chinese medicine for 1 hour every day, then face cleaning is carried out, and the facial muscles are relaxed for 30min at the room temperature of 22-25 ℃ and the relative humidity of 55 +/-5%. An Ina high-precision skin detector is used for detecting the moisture index of the facial skin, the probe repeatedly measures for 3 times in the same measured area during measurement, and an average value is obtained. Skin age was measured using a skin test instrument from day lily of the family, and the results are shown in tables 2-3.
TABLE 1 comparative experiment results for scald repair
| Test object | Scabbing time (hours) |
| White rat 1 | 10 |
| White rat 2 | 9 |
| White rat 3 | 11 |
| White rat 4 | 10 |
| White rat 5 | 9 |
| Average | 9.8 |
TABLE 2 comparative anti-aging test results
| Test object | Before the experiment | Day 1 | Day 2 | Day 3 | Day 4 | Day 5 |
| Volunteer 1 | 40.12 | 38.52 | 36.99 | 35.70 | 34.45 | 33.08 |
| Volunteer 2 | 38.56 | 37.21 | 35.92 | 34.49 | 33.35 | 32.15 |
| Volunteer 3 | 39.10 | 37.86 | 36.35 | 35.19 | 33.96 | 32.73 |
| Volunteer 4 | 38.75 | 37.63 | 36.58 | 35.12 | 33.76 | 32.58 |
| Volunteer 5 | 38.45 | 37.23 | 35.75 | 34.49 | 33.39 | 32.30 |
| Mean age | 39.00 | 37.69 | 36.32 | 35.00 | 33.78 | 32.57 |
| Cumulative increment | 0.00 | -1.31 | -2.68 | -4.00 | -5.22 | -6.43 |
TABLE 3 comparison of the results of the Water supplement treatment
| Test object | Before the experiment | Day 1 | Day 2 | Day 3 | Day 4 | Day 5 |
| Volunteer 1 | 35.72 | 36.26 | 36.80 | 37.35 | 37.91 | 38.48 |
| Volunteer 2 | 36.64 | 37.15 | 37.71 | 38.28 | 38.77 | 39.36 |
| Volunteer 3 | 37.32 | 37.88 | 38.45 | 39.02 | 39.61 | 40.16 |
| Volunteer 4 | 36.28 | 36.82 | 37.30 | 37.86 | 38.43 | 39.01 |
| Volunteer 5 | 36.51 | 37.09 | 37.65 | 38.18 | 38.75 | 39.33 |
| Average water content | 36.49 | 37.04 | 37.58 | 38.14 | 38.70 | 39.27 |
| Cumulative increment | 0.00 | 0.55 | 1.09 | 1.64 | 2.20 | 2.77 |
Experimental example 2:
(1) comparative experiment for scald repair of white rat: taking 25 white rats with the weight of about 110g, carrying out back unhairing treatment by using 6.5% sodium sulfide solution, wherein the unhairing area is 2.5cm multiplied by 2.0cm, and normally feeding the white rats for 12h after being washed clean by deionized water. The wounds were cut along the depilated site with a laser beam after anaesthesia with ether at a cutting rate of 0.5m/min, resulting in post-operative wounds which were then randomly divided into five groups of 5 per group. Then, the repair quick-cleaning gel (cleansing lotion), the repair refreshing spray (toner), the repair and maintenance ice liquid (essence), the repair and maintenance gel (repair lotion) and the repair and maintenance cream (cream) prepared by the formulation and the preparation method of example 2 were applied in the order of application, and were replaced every 2 hours, up to 10 times, with the scab as a healing judgment condition and the scab time as a comparative index, and the experimental results are shown in table 4.
(2) Anti-aging and moisturizing treatment contrast experiment: 25 female volunteers with history of hyaluronic acid injection and facial rigidity symptoms are collected, the female volunteers are aged 35-40 years, have the weight of 45-55kg, have no other facial skin diseases, have similar skin elasticity values and skin water content, and are randomly divided into five groups of 5 persons in each group. Then, the repair quick-cleaning gel (face cleaning lotion), the repair refreshing spray (skin toner), the repair and maintenance ice liquid (essence), the repair and maintenance gel (repair lotion) and the repair and maintenance cream (face cream) prepared by the formula and the preparation method of the embodiment 2 are coated in the coating sequence, the operation is carried out 2 times in the morning and at the evening every day for 5 days in total, the moisture indexes of the facial skin before and after the experiment and the indexes reflecting the skin age are detected and recorded by a skin detector, and the average value of each group calculated on the same day is used as a comparison index. The tested volunteers apply the anti-aging medical biological repair dressing containing the traditional Chinese medicine for 1 hour every day, then face cleaning is carried out, and the facial muscles are relaxed for 30min at the room temperature of 22-25 ℃ and the relative humidity of 55 +/-5%. An Ina high-precision skin detector is used for detecting the moisture index of the facial skin, the probe repeatedly measures for 3 times in the same measured area during measurement, and an average value is obtained. Skin age was measured using a skin test instrument from Kexuan Hemerocallis, and the results are shown in tables 5-6.
TABLE 4 comparative experiment results for scald repair
| Test object | Scabbing time (hours) |
| White rat 1 | 9 |
| White rat 2 | 10 |
| White rat 3 | 9 |
| White rat 4 | 10 |
| White rat 5 | 9 |
| Average | 9.4 |
TABLE 5 comparative anti-aging test results
| Test object | Before the experiment | Day 1 | Day 2 | Day 3 | Day 4 | Day 5 |
| Volunteer 1 | 40.21 | 38.21 | 36.34 | 34.57 | 32.86 | 31.25 |
| Volunteer 2 | 37.27 | 35.41 | 33.69 | 32.01 | 30.45 | 28.93 |
| Volunteer 3 | 39.44 | 37.55 | 35.73 | 33.98 | 32.29 | 30.71 |
| Volunteer 4 | 38.25 | 36.38 | 34.62 | 32.90 | 31.29 | 29.73 |
| Volunteer 5 | 38.43 | 36.52 | 34.73 | 33.04 | 31.43 | 29.89 |
| Mean age | 38.72 | 36.81 | 35.02 | 33.30 | 31.66 | 30.10 |
| Cumulative increment | 0.00 | -1.91 | -3.70 | -5.42 | -7.06 | -8.62 |
TABLE 6 comparative Experimental results of Water supplement treatment
Experimental example 3:
(1) comparative experiment for scald repair of white rat: taking 25 white rats with the weight of about 110g, carrying out back unhairing treatment by using 6.5% sodium sulfide solution, wherein the unhairing area is 2.5cm multiplied by 2.0cm, and normally feeding the white rats for 12h after being washed clean by deionized water. The wounds were cut along the depilated site with a laser beam after anaesthesia with ether at a cutting rate of 0.5m/min, resulting in post-operative wounds which were then randomly divided into five groups of 5 per group. Then, the repair quick-cleaning gel (cleansing lotion), the repair refreshing spray (toner), the repair and maintenance ice liquid (essence), the repair and maintenance gel (repair lotion) and the repair and maintenance cream (cream) prepared by the formulation and the preparation method of example 2 were applied in the order of application, and were replaced every 2 hours, up to 10 times, with the scab as a healing judgment condition and the scab time as a comparative index, and the experimental results are shown in table 7.
(2) Anti-aging and moisturizing treatment contrast experiment: 25 female volunteers with history of hyaluronic acid injection and facial rigidity symptoms are collected, the female volunteers are aged 35-40 years, have the weight of 45-55kg, have no other facial skin diseases, have similar skin elasticity values and skin water content, and are randomly divided into five groups of 5 persons in each group. Then, the repair quick-cleaning gel (face cleaning lotion), the repair refreshing spray (skin toner), the repair and maintenance ice liquid (essence), the repair and maintenance gel (repair lotion) and the repair and maintenance cream (face cream) prepared by the formula and the preparation method of the embodiment 2 are coated in the coating sequence, the operation is carried out 2 times in the morning and at the evening every day for 5 days in total, the moisture indexes of the facial skin before and after the experiment and the indexes reflecting the skin age are detected and recorded by a skin detector, and the average value of each group calculated on the same day is used as a comparison index. The tested volunteers apply the anti-aging medical biological repair dressing containing the traditional Chinese medicine for 1 hour every day, then face cleaning is carried out, and the facial muscles are relaxed for 30min at the room temperature of 22-25 ℃ and the relative humidity of 55 +/-5%. An Ina high-precision skin detector is used for detecting the moisture index of the facial skin, the probe repeatedly measures for 3 times in the same measured area during measurement, and an average value is obtained. Skin age was measured using a skin test instrument from Kexuan Hemerocallis, and the results are shown in tables 8-9.
Table 7 comparative experiment results for scald repair
| Test object | Scabbing time (hours) |
| White rat 1 | 13 |
| White rat 2 | 12 |
| White rat 3 | 11 |
| White rat 4 | 12 |
| White rat 5 | 13 |
| Average | 12.2 |
TABLE 8 comparative anti-aging test results
| Test object | Before the experiment | Day 1 | Day 2 | Day 3 | Day 4 | Day 5 |
| Volunteer 1 | 39.56 | 38.18 | 37.12 | 36.54 | 35.95 | 35.27 |
| Volunteer 2 | 38.40 | 37.06 | 36.14 | 35.57 | 35.04 | 34.38 |
| Volunteer 3 | 37.42 | 36.12 | 35.15 | 34.49 | 33.94 | 33.34 |
| Volunteer 4 | 38.75 | 37.40 | 36.36 | 35.79 | 35.18 | 34.55 |
| Volunteer 5 | 38.15 | 36.82 | 35.80 | 35.23 | 34.68 | 34.06 |
| Mean age | 38.46 | 37.12 | 36.12 | 35.52 | 34.96 | 34.32 |
| Cumulative increment | 0.00 | -1.34 | -2.34 | -2.93 | -3.50 | -4.13 |
TABLE 9 comparative Experimental results of Water supplement treatment
| Test object | Before the experiment | Day 1 | Day 2 | Day 3 | Day 4 | Day 5 |
| Volunteer 1 | 36.24 | 36.78 | 37.15 | 37.89 | 38.65 | 39.04 |
| Volunteer 2 | 37.24 | 37.69 | 38.14 | 38.33 | 38.90 | 39.10 |
| Volunteer 3 | 37.15 | 37.71 | 38.08 | 38.54 | 38.93 | 39.32 |
| Volunteer 4 | 36.45 | 36.81 | 37.33 | 37.70 | 38.46 | 39.23 |
| Volunteer 5 | 36.63 | 37.15 | 37.52 | 37.97 | 38.42 | 38.81 |
| Average water content | 36.74 | 37.23 | 37.64 | 38.09 | 38.67 | 39.10 |
| Cumulative increment | 0.00 | 0.49 | 0.90 | 1.34 | 1.93 | 2.35 |
Experimental example 4:
common anti-aging skin care products which do not contain traditional Chinese medicines and have the same content of sodium hyaluronate are selected and coated according to the coating sequence of the face cleansing cream, the skin toner, the essence, the skin care cream and the face cream, the experimental method is the same as that of the examples 1-3, and the experimental results are shown in tables 10-12.
Comparative experiment result for repairing surface 10 scald
| Test object | Scabbing time (hours) |
| White rat 1 | 14 |
| White rat 2 | 13 |
| White rat 3 | 13 |
| White rat 4 | 14 |
| White rat 5 | 15 |
| Average | 13.8 |
TABLE 11 comparative anti-aging test results
| Test object | Before the experiment | Day 1 | Day 2 | Day 3 | Day 4 | Day 5 |
| Volunteer 1 | 37.72 | 37.31 | 36.91 | 36.51 | 36.13 | 35.74 |
| Volunteer 2 | 37.45 | 37.05 | 36.65 | 36.25 | 35.86 | 35.47 |
| Volunteer 3 | 38.50 | 38.08 | 37.67 | 37.27 | 36.86 | 36.47 |
| Volunteer 4 | 39.70 | 39.27 | 38.85 | 38.43 | 38.01 | 37.60 |
| Volunteer 5 | 36.84 | 36.44 | 36.07 | 35.68 | 35.30 | 34.91 |
| Mean age | 38.04 | 37.63 | 37.23 | 36.83 | 36.43 | 36.04 |
| Cumulative increment | 0.00 | -0.41 | -0.81 | -1.21 | -1.61 | -2.00 |
TABLE 12 comparative Experimental results of Water supplement treatment
Experimental example 5:
common anti-aging skin care products containing other traditional Chinese medicines and having the same sodium hyaluronate content in the existing products are selected and coated according to the coating sequence of the face cleansing cream, the skin toner, the essence, the skin care cream and the face cream, the experimental method is the same as that of examples 1-3, and the experimental results are shown in tables 13-15.
Comparative experiment result for repairing surface 13 scald
| Test object | Scabbing time (hours) |
| White rat 1 | 13 |
| White rat 2 | 12 |
| White rat 3 | 14 |
| White rat 4 | 13 |
| White rat 5 | 13 |
| Average | 13 |
TABLE 14 comparative anti-aging test results
| Test object | Before the experiment | Day 1 | Day 2 | Day 3 | Day 4 | Day 5 |
| Volunteer 1 | 37.65 | 36.94 | 36.25 | 35.57 | 34.90 | 34.45 |
| Volunteers2 | 37.54 | 36.98 | 36.44 | 35.90 | 35.37 | 34.84 |
| Volunteer 3 | 38.06 | 37.53 | 36.83 | 36.14 | 35.46 | 34.97 |
| Volunteer 4 | 39.03 | 38.45 | 37.86 | 37.26 | 36.78 | 36.24 |
| Volunteer 5 | 37.87 | 37.35 | 36.76 | 36.07 | 35.39 | 34.72 |
| Mean age | 38.03 | 37.45 | 36.83 | 36.19 | 35.58 | 35.04 |
| Cumulative increment | 0.00 | -0.58 | -1.20 | -1.84 | -2.45 | -2.99 |
TABLE 15 comparative Experimental results of Water supplement treatment
| Test object | Before the experiment | Day 1 | Day 2 | Day 3 | Day 4 | Day 5 |
| Volunteer 1 | 36.18 | 36.49 | 36.79 | 37.11 | 37.43 | 37.74 |
| Volunteer 2 | 37.05 | 37.36 | 37.67 | 38.00 | 38.32 | 38.65 |
| Volunteer 3 | 36.25 | 36.54 | 36.85 | 37.16 | 37.48 | 37.79 |
| Volunteer 4 | 36.74 | 37.05 | 37.37 | 37.68 | 38.01 | 38.32 |
| Volunteer 5 | 36.82 | 37.13 | 37.44 | 37.76 | 38.08 | 38.41 |
| Average water content | 36.61 | 36.91 | 37.22 | 37.54 | 37.86 | 38.18 |
| Cumulative increment | 0.00 | 0.31 | 0.62 | 0.93 | 1.25 | 1.58 |
Experimental examples 1-5 comprehensive comparative analysis of comparative experiments on scald skin repair and comparative experiments on anti-aging and moisturizing treatments, the results are shown in tables 16-18:
TABLE 16 Experimental examples 1-5 comparative experimental results for scald repair
TABLE 17 Experimental examples 1-5 comparative results of antiaging
TABLE 18 Experimental examples 1-5 comparative experimental results of water supplement treatment
Experimental examples 1-5 experimental data comparison results:
(1) the data in table 16 show that the anti-aging medical biological repair dressing containing traditional Chinese medicines (formula in example 2) provided by the invention has the best scabbing effect on the scald part, and is 9.4 h; when the anti-aging medical biological repair dressing containing traditional Chinese medicines (formula in example 1) provided by the invention is used, the scabbing effect of the scald part is the second, and is 9.8 h; when the anti-aging medical biological repair dressing containing traditional Chinese medicines (formula in example 3) provided by the invention is used, the scabbing effect of the scald part is the third, and is 12.2 hours; when the common anti-aging skin care product containing other traditional Chinese medicines in the existing product is used, the scabbing effect of the scalded part is fourth, and is 13.0 h; when the common anti-aging skin care product without traditional Chinese medicines in the existing products is used, the scabbing time of the scalded part is the longest and is 13.8 hours. Experimental data show that the anti-aging medical biological repair dressing containing traditional Chinese medicines has the treatment effect of skin repair compared with the common anti-aging skin care product without traditional Chinese medicines in the existing product.
(2) The data in table 17 show that the anti-aging medical bioremediation dressing containing traditional Chinese medicines (formula in example 2) provided by the invention has the best anti-aging effect, and the index of skin age is 30.10; by using the anti-aging medical biological repair dressing containing traditional Chinese medicines (formula in example 1), the anti-aging effect is the second, and the skin age index is 32.57; by using the anti-aging medical biological repair dressing containing traditional Chinese medicines (formula in example 3), the anti-aging effect is the third, and the skin age index is 34.32; the common anti-aging skin care product containing other traditional Chinese medicines in the existing product is used, the anti-aging effect is fourth, and the index of skin age is 35.04; the common anti-aging skin care product without traditional Chinese medicines in the existing products is used, the anti-aging effect is the worst, and the index of skin age is 36.04. Experimental data show that the anti-aging medical biological repair dressing containing traditional Chinese medicines has an anti-aging treatment effect compared with the common anti-aging skin care product without traditional Chinese medicines in the existing product.
(3) The data in table 18 show that the anti-aging medical biological repair dressing containing traditional Chinese medicines (formula in example 2) provided by the invention has the best moisturizing effect, and the skin moisture index is 41.16; by using the anti-aging medical biological repair dressing containing traditional Chinese medicines (formula in example 1), the second moisturizing effect is achieved, and the moisture index of the skin is 39.27; by using the anti-aging medical biological repair dressing containing traditional Chinese medicines (formula in example 3), the moisturizing effect is the third, and the moisture index of skin is 39.10; the common anti-aging skin care product containing other traditional Chinese medicines in the existing product is used, the moisturizing effect is the fourth, and the moisture index of the skin is 38.18; the common anti-aging skin care product which does not contain traditional Chinese medicines in the existing products is used, the moisturizing effect is the worst, and the moisture index of the skin is 37.23. Experimental data show that compared with the common anti-aging skin care product without traditional Chinese medicines in the existing product, the anti-aging medical biological repair dressing containing traditional Chinese medicines provided by the invention enhances the effects of moisturizing and moisturizing the skin.
(4) The effect rankings in tables 16-18 show that the anti-aging medical bioremediation dressing made according to the traditional Chinese medicine formula provided by the present invention has the best treatment effects of anti-aging, skin repair, and moisturizing compared to the two anti-aging medical bioremediation dressings containing traditional Chinese medicines provided by the present invention that adjust the amount of the mixed concentrated solution of the traditional Chinese medicine formula.
(5) The effect rankings in tables 16-18 show that the anti-aging medical bioremediation dressing made according to the traditional Chinese medicine formula provided by the invention has the best treatment effects of anti-aging, skin repair and moisturizing compared with the common anti-aging skin care products containing other traditional Chinese medicines in the existing products.
Claims (9)
1. The anti-aging medical biological repair dressing containing traditional Chinese medicines is characterized by comprising the following raw materials in parts by weight: 5-10 parts of lucid ganoderma, 10-15 parts of poria cocos, 5-10 parts of mulberry leaves, 3-10 parts of common perilla, 6-10 parts of ginkgo kernels, 6-10 parts of tribulus terrestris, 3-10 parts of bletilla striata, 5-10 parts of white chrysanthemum, 0.1-0.5 part of sodium hyaluronate, 3-6 parts of glycerol and auxiliary materials.
2. The anti-aging medical bioremediation dressing containing traditional Chinese medicines according to claim 1, wherein: the dressing is a repair quick-cleaning water gel, and auxiliary materials of the dressing comprise the following raw materials in parts by weight: 100-150 parts of deionized water, 1-3 parts of vitamin E, 1-3 parts of amino acid, 1-5 parts of hydrolyzed collagen, 6-10 parts of sodium laureth sulfate, 1-2 parts of acetylated hexapeptide, 1-3 parts of ursolic acid, 2-5 parts of human-like collagen, 3-8 parts of lecithin and 3-5 parts of xanthan gum.
3. The anti-aging medical bioremediation dressing containing traditional Chinese medicines according to claim 1, wherein: the dressing is skin care spray, and the auxiliary materials of the dressing are composed of the following raw materials in parts by weight: 100 portions of deionized water, 150 portions of vitamin E, 0.5 to 1 portion of amino acid, 0.5 to 1 portion of hydrolyzed collagen, 1 to 3 portions of sodium laureth sulfate, 0.5 to 1 portion of acetylated hexapeptide, 0.5 to 2 portions of ursolic acid and 1 to 2 portions of human-like collagen.
4. The anti-aging medical bioremediation dressing containing traditional Chinese medicines according to claim 1, wherein: the dressing is repair and maintenance ice water, repair and maintenance ice liquid or repair and maintenance ice dew, and the auxiliary material of the dressing is composed of the following raw materials in parts by weight: 100-150 parts of deionized water, 1-3 parts of vitamin E, 1-3 parts of amino acid, 1-5 parts of hydrolyzed collagen, 1-2 parts of acetylated hexapeptide, 1-3 parts of ursolic acid and 2-5 parts of human-like collagen.
5. The anti-aging medical bioremediation dressing containing traditional Chinese medicines according to claim 1, wherein: the dressing is repairing and maintaining ice cream, and the auxiliary materials of the dressing comprise the following raw materials in parts by weight: 100-150 parts of deionized water, 1-3 parts of vitamin E, 1-3 parts of amino acid, 1-5 parts of hydrolyzed collagen, 1-2 parts of acetylated hexapeptide, 1-3 parts of ursolic acid, 2-5 parts of human-like collagen, 6-9 parts of lecithin and 3-6 parts of xanthan gum.
6. The anti-aging medical bioremediation dressing containing traditional Chinese medicines according to claim 1, wherein: the dressing is a repairing and nourishing gel, and the auxiliary materials of the dressing are composed of the following raw materials in parts by weight: 100-150 parts of deionized water, 1-3 parts of vitamin E, 1-3 parts of amino acid, 1-5 parts of hydrolyzed collagen, 1-2 parts of acetylated hexapeptide, 1-3 parts of ursolic acid, 2-5 parts of human-like collagen, 9-12 parts of lecithin and 6-10 parts of xanthan gum.
7. The anti-aging medical bioremediation dressing containing traditional Chinese medicines according to claim 1, wherein: the dressing is a repairing nourishing paste, and the auxiliary materials of the dressing are composed of the following raw materials in parts by weight: 100-150 parts of deionized water, 1-3 parts of vitamin E, 1-3 parts of amino acid, 1-5 parts of hydrolyzed collagen, 1-2 parts of acetylated hexapeptide, 1-3 parts of ursolic acid, 2-5 parts of human-like collagen, 10-15 parts of lecithin and 9-12 parts of xanthan gum.
8. The method for preparing the anti-aging medical bioremediation dressing containing traditional Chinese medicines according to any one of claims 1 to 7, which is characterized by comprising the following steps:
(1) preparing Ganoderma, Poria, folium Mori, rhizoma Stachydis Japonicae, semen Ginkgo, fructus Atriplicis Sibiricae, rhizoma Bletillae and flos Chrysanthemi into nanometer Chinese medicinal powder mixture by nanometer Chinese medicinal powder preparation process;
(2) mixing the nanometer Chinese medicinal powder mixture obtained in step (1) with 10-25L deionized water by static boiling method, decocting for 45-100min, and cooling to 40-60 deg.C to obtain Chinese medicinal mixed concentrated solution;
(3) heating deionized water to 80-85 deg.C, adding sodium hyaluronate and glycerol, homogenizing, and keeping the temperature for 5-10min to obtain sodium hyaluronate mixture;
(4) and (3) cooling the sodium hyaluronate mixture obtained in the step (3) to 40-50 ℃, adding different amounts of the traditional Chinese medicine mixed concentrated solution obtained in the step (2) according to dosage forms, adding different auxiliary materials according to dosage forms, homogenizing, cooling to 38 ℃, standing until the solution is completely swelled, and thus obtaining the anti-aging medical biological repair dressing containing traditional Chinese medicines.
9. The method for preparing the anti-aging medical bioremediation dressing containing traditional Chinese medicines according to claim 8, wherein: adding the traditional Chinese medicine mixed concentrated solution with different dosage according to the dosage form in the step (4):
respectively adding 20-40% of the traditional Chinese medicine mixed concentrated solution into the repairing quick-cleaning water gel and the repairing nourishing gel;
adding 5-10% of the Chinese medicinal concentrated solution into the skin care spray;
adding 40-60% of the traditional Chinese medicine mixed concentrated solution into the repair and maintenance ice water;
adding 60-80% of the Chinese medicinal concentrated solution into the repairing and maintaining ice liquid;
respectively adding 80-100% of the Chinese medicinal concentrated solution into the repairing and maintaining ice cream and the repairing and maintaining ice cream;
the repairing and nourishing cream is added with 100 percent of traditional Chinese medicine mixed concentrated solution.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN114288391A (en) * | 2022-02-16 | 2022-04-08 | 西安拜尔海森生物制药有限公司 | Antibacterial and anti-inflammatory lotion for women and preparation method thereof |
| CN115364266A (en) * | 2022-09-26 | 2022-11-22 | 南京创焕媄生物技术服务中心 | Anti-aging nursing dressing and preparation method thereof |
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| CN102525870A (en) * | 2012-02-23 | 2012-07-04 | 李进 | Traditional Chinese medicine beauty mask |
| CN105125473A (en) * | 2015-09-15 | 2015-12-09 | 杨塞红 | Skin whitening and moistening traditional Chinese medicine mask |
| CN105687041A (en) * | 2016-03-10 | 2016-06-22 | 广西大学 | Freckle removing and whitening clay mask |
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| CN102525870A (en) * | 2012-02-23 | 2012-07-04 | 李进 | Traditional Chinese medicine beauty mask |
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| CN105687041A (en) * | 2016-03-10 | 2016-06-22 | 广西大学 | Freckle removing and whitening clay mask |
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| CN114288391A (en) * | 2022-02-16 | 2022-04-08 | 西安拜尔海森生物制药有限公司 | Antibacterial and anti-inflammatory lotion for women and preparation method thereof |
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