CN110741251A - 液相分析装置及用于该液相分析装置的分析方法 - Google Patents

液相分析装置及用于该液相分析装置的分析方法 Download PDF

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Publication number
CN110741251A
CN110741251A CN201780091923.4A CN201780091923A CN110741251A CN 110741251 A CN110741251 A CN 110741251A CN 201780091923 A CN201780091923 A CN 201780091923A CN 110741251 A CN110741251 A CN 110741251A
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fluid
sample
injection valve
supply system
fluid supply
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CN110741251B (zh
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李江波
滕锦
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/16—Injection
    • G01N30/20—Injection using a sampling valve
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N2030/022—Column chromatography characterised by the kind of separation mechanism
    • G01N2030/027—Liquid chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/16—Injection
    • G01N30/20—Injection using a sampling valve
    • G01N2030/207—Injection using a sampling valve with metering cavity, e.g. sample loop

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

一种液相分析装置(100)及分析方法，液相分析装置(100)包括用于驱动第一流体或待测样本的第一流体供给系统(110)、用于驱动第二流体的第二流体供给系统(120)、与第二流体供给系统(120)和第一流体供给系统(110)连接的进样阀(130)，与进样阀(130)连接的层析柱(140)、以及与层析柱(140)连接的检测器(150)；层析柱(140)用于分离待测样本中的成分；检测器(150)用于检测待测样本中的被层析柱(140)分离出的成分；进样阀(130)用于切换流路使第一流体供给系统(110)、第二流体供给系统(120)与层析柱(140)流路连通。该液相分析装置(100)及分析方法，简化了系统的复杂度，减少了仪器元件的数量且降低了对元件的性能要求，从而降低了实现的成本。

Description

PCT国内申请，说明书已公开。

Claims (18)

  1. PCT国内申请，权利要求书已公开。
CN201780091923.4A 2017-07-05 2017-07-05 液相分析装置及用于该液相分析装置的分析方法 Active CN110741251B (zh)

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PCT/CN2017/091908 WO2019006710A1 (zh) 2017-07-05 2017-07-05 液相分析装置及用于该液相分析装置的分析方法

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Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003247987A (ja) * 2002-02-27 2003-09-05 Shimadzu Corp 液体クロマトグラフシステム
US20050016263A1 (en) * 2001-06-07 2005-01-27 Yoshio Yamauchi Liquid chromatograph and analysis system
WO2010041637A1 (ja) * 2008-10-07 2010-04-15 アークレイ株式会社 液体クロマトグラフィ装置および液体クロマトグラフィ
CN103308610A (zh) * 2012-03-08 2013-09-18 株式会社岛津制作所 送液装置以及液相色谱仪
US20150040648A1 (en) * 2013-08-07 2015-02-12 Arkray, Inc. Liquid chromatography device, liquid chromatography analysis process, and non-transitory computer-readable medium
WO2016156153A1 (en) * 2015-03-31 2016-10-06 Ge Healthcare Bio-Sciences Ab A liquid chromatograhy system, a device, and a method
CN106290592A (zh) * 2015-05-18 2017-01-04 深圳迈瑞生物医疗电子股份有限公司 高效液相色谱装置及其工作方法
CN205982189U (zh) * 2016-07-25 2017-02-22 深圳市大公检测技术有限公司 液相色谱仪

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1749750A (zh) * 2004-09-13 2006-03-22 聂智明 高效液相色谱仪
CN203490202U (zh) * 2013-09-23 2014-03-19 王飞 一种高效液相色谱仪
JP6516010B2 (ja) * 2015-07-27 2019-05-22 株式会社島津製作所 自動配管接続装置
CN206292212U (zh) * 2016-12-20 2017-06-30 中南大学湘雅医院 高效液相色谱仪

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050016263A1 (en) * 2001-06-07 2005-01-27 Yoshio Yamauchi Liquid chromatograph and analysis system
JP2003247987A (ja) * 2002-02-27 2003-09-05 Shimadzu Corp 液体クロマトグラフシステム
WO2010041637A1 (ja) * 2008-10-07 2010-04-15 アークレイ株式会社 液体クロマトグラフィ装置および液体クロマトグラフィ
CN102171562A (zh) * 2008-10-07 2011-08-31 爱科来株式会社 液相层析装置和液相层析法
CN103308610A (zh) * 2012-03-08 2013-09-18 株式会社岛津制作所 送液装置以及液相色谱仪
US20150040648A1 (en) * 2013-08-07 2015-02-12 Arkray, Inc. Liquid chromatography device, liquid chromatography analysis process, and non-transitory computer-readable medium
WO2016156153A1 (en) * 2015-03-31 2016-10-06 Ge Healthcare Bio-Sciences Ab A liquid chromatograhy system, a device, and a method
CN106290592A (zh) * 2015-05-18 2017-01-04 深圳迈瑞生物医疗电子股份有限公司 高效液相色谱装置及其工作方法
CN205982189U (zh) * 2016-07-25 2017-02-22 深圳市大公检测技术有限公司 液相色谱仪

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KOHLER DA 等: "Preparative liquid chromatography by automatic repetitive injection", 《AMERICAN LABORATORY》 *
姚珈 等: "微型电动色谱系统的设计", 《分析仪器》 *

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WO2019006710A1 (zh) 2019-01-10
US20200141911A1 (en) 2020-05-07
US11204338B2 (en) 2021-12-21
CN110741251B (zh) 2022-09-09

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