CN110711165A - Anti-aging firming beauty cream containing kangaroo paw extract - Google Patents

Anti-aging firming beauty cream containing kangaroo paw extract Download PDF

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CN110711165A
CN110711165A CN201911062563.2A CN201911062563A CN110711165A CN 110711165 A CN110711165 A CN 110711165A CN 201911062563 A CN201911062563 A CN 201911062563A CN 110711165 A CN110711165 A CN 110711165A
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aging
extract
skin
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kangaroo paw
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汪雪峰
张目
李继德
李书乾
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SHANGHAI YUEMU COSMETICS Co Ltd
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SHANGHAI YUEMU COSMETICS Co Ltd
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    • A61K8/89Polysiloxanes
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Abstract

The invention provides anti-aging firming beauty cream containing kangaroo paw extract, which mainly comprises the following components in percentage by weight: 0.2-2% of kangaroo paw extract, 0.01-0.2% of ergothioneine, 31.0-5.0% of acetyl octapeptide and 0.01-0.2% of carnosine. According to the anti-aging firming beauty cream, the kangaroo paw extract, ergothioneine, acetyl octapeptide-3 and carnosine are added as main anti-aging functional ingredients, and then the buddleja officinalis extract, glycosphingolipids and carbohydrate isomers are compounded in a synergistic manner, so that under the action of different targets, the active ingredients have a good synergistic interaction effect, the synthesis of elastin and collagen can be increased, excessive free radicals can be efficiently eliminated, ultraviolet radiation can be resisted, and the anti-aging cream has a remarkable anti-aging effect.

Description

Anti-aging firming beauty cream containing kangaroo paw extract
Technical Field
The invention relates to the field of cosmetics, and in particular relates to anti-aging firming beauty cream containing kangaroo paw extract.
Background
With the improvement of living standard and the rapid advance of China to aging society, people pay more and more attention to anti-aging maintenance, hope to keep young forever and reduce the aging trace to the minimum. With the increasing age, the pace of life is accelerated, the working pressure is increased and the environmental pollution is more and more serious, the skin aging of people is more and more obvious. Anti-aging skin care products are also receiving more and more attention and favored by people, and the proportion of the anti-aging skin care products in the cosmetic market is promoted year by year.
Furthermore, consumers with an anti-aging need today are increasingly moving toward youthfulness, mainly focusing on the age of 25 to 45 years. A survey of mature women made in 2017, inmite, enjoyed by 70% of the population a brand that solved the aging problem in a preventive manner. According to the Chinese cosmetic industry market survey report, the mention rate of the anti-aging maintenance service item which is most concerned and most popular by women in all items is up to 72.2 percent, the anti-aging becomes the skin care effect which is most concerned by consumers, and according to research, the share of Chinese anti-aging cosmetics reaches 23 percent, so that the Chinese anti-aging cosmetics become the first major category.
Skin aging refers to the aging damage of skin function, which reduces the protection ability and regulation ability of skin to human body, so that the skin can not adapt to the change of internal and external environment, and the appearance of the whole condition such as color, shape and texture changes.
Skin aging is a process by which the human body functions or develops rapidly or slowly naturally under the influence of internal and external factors, mainly due to endogenous aging (time accumulation) and exogenous aging (external exposure to the environment). Endogenous aging is an irresistible complex natural law and mainly shows that cell metabolism is gradually slowed down, collagen is gradually lost, collagen is damaged, hormone secretion is disordered, fat content begins to be reduced, partial cells are naturally killed and the like, and the conditions that skin loses elasticity and luster, skin is dried to generate wrinkles, and even melanin pigmentation, senile plaques are generated and the like are accelerated on the skin. Exogenous aging is mainly affected by environmental pollution, excessive ultraviolet irradiation, haze, computer blue light radiation, high working pressure, irregular diet, overnight stay, excessive intake of irritant food and other factors. The change of the dermis structure in the skin aging process is the main reason of causing the skin to lose elasticity, relax and generate wrinkles, and the anti-aging cosmetics can be used to stimulate the regeneration of skin collagen and elastin to a certain extent so as to realize the effect of repairing the dermis and achieve the aim of resisting aging.
The molecular mechanisms of skin aging include: oxidative damage, inflammatory reactions, DNA damage, reduced antioxidant production, and the production of a family of Matrix Metalloproteinases (MMPs) that degrade collagen and elastin in the dermal skin layer. These mechanisms cause skin aging and damage to the skin structure, which is characterized by the breakdown of extracellular matrix (ECM) structures, formation of age spots, and loss of skin tensile strength and elasticity. At present, many anti-aging ingredients are applied to cosmetics, such as vitamins, polypeptides, coenzymes, collagen, plant extracts, and the like. The traditional anti-aging products mostly adopt single anti-oxidation or single collagen supplement, and the like, have insignificant anti-aging effect and no effect of resisting ultraviolet radiation.
Therefore, the anti-aging firming beauty cream which can comprehensively solve the problem of skin aging by compounding and using a plurality of anti-aging components is necessary.
Disclosure of Invention
The invention aims to provide anti-aging firming beauty cream containing kangaroo paw extract.
In order to achieve the purpose, the specific technical scheme of the invention is as follows:
an anti-aging firming beauty cream containing kangaroo paw extract mainly comprises the following components in percentage by weight:
0.2-2.0% of kangaroo paw (ANIGOZANTHOS FLAVIDUS) extract,
0.01 to 0.2 percent of ergothioneine,
1.0-5.0% of 1 ‰ aqueous solution of acetyl octapeptide-3,
Carnosine 0.01-0.2%.
In some embodiments, the anti-aging firming and beautifying cream containing the kangaroo paw extract further comprises the following components in percentage by weight:
0.1-1.0% of extract of flos Buddlejae (Buddleja OFFICINALIS),
0.1-0.4% of glycosphingolipids,
Saccharide isomerate 0.1-0.5%.
In some embodiments, the anti-aging firming and beautifying cream containing the kangaroo paw extract further comprises the following components in percentage by weight: 2.8 to 5.1 percent of emulsifier, 5.65 to 15.25 percent of emollient, 4.5 to 13.0 percent of polyol, 1.48 to 4.0 percent of thickening stabilizer, 1.0 percent of antibacterial agent, 0.3 to 1.2 percent of anti-allergy agent and 0.09 to 0.21 percent of pH value regulator.
The emulsifier can be one or a mixture of more than one of polyglycerol-6 distearate, C14-22 alcohol, C12-20 alkyl glucoside, hydrogenated lecithin, glyceryl stearate SE, cetearyl cornstalk glycoside, cetearyl alcohol, cocoyl glucoside, cetyl alcohol, PEG-75 stearate, ceteth-20, steareth-20, cetearyl glucoside, cetearyl olive oleate, sorbitan olive oleate, glyceryl stearate and PEG-100 stearate.
In some of these embodiments, the emulsifier consists of cetearyl alcohol/cetearyl glucoside, cetearyl olive oleate/sorbitan olive oleate, glyceryl stearate/PEG-100 stearate, the mass ratio of cetearyl alcohol/cetearyl glucoside, cetearyl olive oleate/sorbitan olive oleate, glyceryl stearate/PEG-100 stearate may be (1.5-2.6): (0.8-2.5): (0.5-1.0).
The emollient described herein can be one or more of caprylic/capric triglyceride, cyclopentadimethylsiloxane, hydrogenated polyisobutene, neopentylglycol diheptanoate, dioctyl carbonate, sunflower (helioanthus ANNUUS) seed oil, cetearyl ethyl hexanoate, pentaerythritol tetraisostearate, butylene glycol dioctanoate/dicaprate, grape (VITIS VINIFERA) seed oil, ROSA CANINA (ROSA CANINA) fruit oil, C12-15 alcohol benzoate, glycerol tri (ethylhexanoate), polydimethylsiloxane, isononyl isononanoate, THEOBROMA grandiflora (THEOBROMA gradiflorum) seed fat, tocopheryl acetate, jojoba (SIMMONDSIA CHINENSIS) seed oil.
In some of these embodiments, the emollient is comprised of glyceryl tri (ethylhexanoate), dimethicone, isononyl isononanoate, THEOBROMA grandiflora (THEOBROMA gradiflorum) seed fat, tocopheryl acetate, jojoba (SIMMONDSIA CHINENSIS) seed oil, wherein the ratio of the amount of glyceryl tri (ethylhexanoate), dimethicone, isononyl isononanoate, THEOBROMA grandiflora (THEOBROMA gradiflorum) seed fat, tocopheryl acetate, jojoba (SIMMONDSIA CHINENSIS) seed oil is (2.0-5.0): (2.0-4.0): (1.0-4.0):(0.1-1.0):(0.15-0.25):(0.4-1.0).
The polyalcohol can be one or a mixture of more of dipropylene glycol, 1, 3-propylene glycol, polyglycerol-10, PPG-10 methyl glucose ether, PEG/PPG-17/6 copolymer, sorbitol, glyceryl polyether-26, butanediol and PPG-24-glyceryl polyether-24.
In some of the embodiments, the polyol is composed of glycerin, butylene glycol, PPG-24-glyceryl polyether-24, and the mass ratio of glycerin, butylene glycol, PPG-24-glyceryl polyether-24 is (2.0-6.0): (2.0-6.0): 0.5-1.0.
The thickening agent can be one or a mixture of more than one of hydroxyethyl cellulose, carbomer sodium, acrylic acid (ester) copolymer, sodium alginate, acrylic acid (ester)/C10-30 alkanol, polyacrylate cross-linked polymer-6, hydroxypropyl methyl cellulose, ammonium acryloyldimethyl taurate/VP copolymer, acrylic acid (ester)/behenyl alcohol polyether-25 methacrylate copolymer, sodium polyacrylate, SCLEROTIUM rolfsii (SCLEOTIUM ROLFSSII) glue, acrylic acid (ester)/vinyl isodecanoate cross-linked polymer, stearic acid, carbomer, xanthan gum, cetearyl alcohol and SIMULGEL EG.
The SIMULGEL EG is an emulsion thickener of SEPPIC company of France, and comprises the following components: sodium acrylate/sodium acryloyldimethyl taurate copolymer/water/isohexadecane/polysorbate-80/sorbitan oleate.
In some of these embodiments, the thickening stabilizer is a mixture of carbomer, xanthan gum, cetostearyl alcohol, SIMULGEL EG, in a mass ratio of (0.15-0.35) to (0.03-0.15): (0.8-2.0): (0.5-1.5).
The antibacterial agent can be a mixture of more than one of methyl hydroxybenzoate, phenoxyethanol, ethylhexyl glycerol, caprylyl hydroxamic acid, glyceryl caprylate, p-hydroxyacetophenone and 1, 2-hexanediol.
In some embodiments, the antibacterial agent is a mixture of p-hydroxyacetophenone and 1, 2-hexanediol, and the mass ratio of the p-hydroxyacetophenone to the 1, 2-hexanediol is (0.5-0.55) to (0.45-0.5).
The antiallergic agent can be one or more of herba Portulacae (Portulaca OLERACEA) extract, radix Paeoniae (Paeonia albiflora) root extract, herba Centellae (CENTELLA ASIATICA) extract, Scutellariae radix (Scutellaria baicalensis) root extract, radix Sophorae Flavescentis (Sophora FLAVESCENS) root extract, radix Glycyrrhizae (Glycyrrhiza inflata) root extract, lactobacillus/soybean milk fermentation product filtrate, hydroxyphenylpropionamide benzoic acid, and panthenol.
In some embodiments, the anti-sensitization agent consists of hydroxyphenylpropionamide benzoic acid and panthenol, and the mass ratio of the hydroxyphenylpropionamide benzoic acid to the panthenol is (0.1-0.2) to (0.2-1.0).
The pH value regulator can be one or more of triethanolamine, arginine, aminomethyl propanol, tromethamine, potassium hydroxide and sodium hydroxide.
In some of these embodiments, the pH adjusting agent is aminomethyl propanol.
In some embodiments, the anti-aging firming and beautifying cream containing the kangaroo paw extract further comprises the following components in percentage by weight: 0.001-0.01% of ROSA DAMASCENA (ROSA DAMASCENA) flower oil, 0.01-0.05% of disodium EDTA, 0.1-0.2% of allantoin and 0.2-1.0% of trehalose.
The technical scheme provided by the embodiment of the invention has the following beneficial effects:
(1) the anti-aging firming and beautifying cream containing the kangaroo paw extract is prepared by selecting the kangaroo paw (Angozanthofulavidus) extract, ergothioneine, acetyl octapeptide-3 and carnosine as main anti-aging effect components, and can be used for synergistic compounding of a Buddleja OFFICINALIS (Buddleja OFFICINALIS) extract, glycosphingolipids and carbohydrate isomers, and under the combined action of different target spots of various active components, the components have good synergistic interaction, so that the anti-aging effect can be exerted to the maximum. Quickly firming skin, improving skin elasticity, and reducing skin relaxation, pigmentation, and facial wrinkle. The skin is kept in a young state with luster, fineness, tightness and elasticity. Experiments prove that the product has no discomfort after being used, and the skin is obviously glossy, more delicate, firmer and elastic after being used for a period of time, thereby effectively delaying skin aging.
(2) The anti-aging firming beauty cream containing the kangaroo paw extract has mild components, does not contain essence, and can be added with French HCF Bagalia rose essential oil, so that the anti-aging firming beauty cream not only provides pleasant fragrance of products and adjusts mood, but also has the effects of sterilizing, relieving inflammation and moisturizing.
(3) The anti-aging firming and beautifying cream containing the kangaroo paw extract has the advantages of simple method, easy process operation, suitability for standardized production and popularization and application, stable system, easy penetration and absorption, soft, moist and refreshing skin feel and no stickiness and greasiness.
Drawings
FIG. 1 skin firmness R7 analysis profile;
FIG. 2 analysis graph of the rate of change of skin firmness R7;
FIG. 3 wrinkle feature count analysis plot over time;
figure 4 wrinkle feature count rate of change over time analysis plot.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, embodiments of the present invention will be described in further detail below, but the embodiments of the present invention are not limited thereto, and process parameters or conditions not particularly noted may be performed with reference to conventional techniques.
The brief introduction of part of the raw materials involved in the invention is as follows:
the kangaroo paw (ANIGOZANTHOS FLAVIDUS) extract is extracted from kangaroo paw. The Kangaroo paws are originally produced in Australia, are widely distributed in Western Australia, and are named because the tubular appearance is attached with velvet-like villi which is exactly like the Kangaroo paws. The kangaroo paw is a peculiar flower in Australia, is elegant and full of vitality, has long flowering period and rich nectar, is rich in fructose and rutin with high content, and is called a 'sheng drink'. Suitable kangaroo paw (Angozanthos FLAVIDUS) extracts may be obtained from the SKINectora-cell of the LUCAS MEYER company.
The acetyl octapeptide-3 can eliminate skin overstrain, relax facial muscles and reduce expression lines caused by facial muscle contraction, and is particularly suitable for forehead and eye wrinkles. Suitable acetyl octapeptide-3 may be from french LIPOTEC under the trade name: SNAP-8.
The butterflybush flower is a shrub plant of buddleja of Loganiaceae, and has wound healing, anti-inflammatory, diuretic, antiallergic, antiviral and antibacterial properties in traditional medicine. Flos Buddlejae (Buddleja officinalis) is mainly distributed in North Vietnam and China, and has simple and compact small branches, red or white color, and villus covered branches, oval leaves, narrow base part, 6-11 cm long, and 2-4 cm wide. The upper part of the butterflybush flower has no hair, and the lower part has short villi and a little membranous substance. Butterflybush flower is generally light purple, has a terminal pyramidal shape up to 15cm in length, consists of polystictus, hairy. A suitable extract of buddleja officinalis (buddleja officinalis) may be obtained from GREENTECH france under the trade name: SOLIBERINE NAT.
The glycosphingolipids of the present invention may be obtained from SEPPIC, France under the tradename CERAMOSIDES HP. Rich in unsaturated fatty acid and natural antioxidant necessary for skin. Protecting the dermis by reestablishing a balance between protease (degrading the dermal extracellular matrix) and its inhibitor (TIMP), protecting the skin by inhibiting the activity of elastase, which degrades elastic fibers in the extracellular matrix, and protecting the skin from oxidative stress.
The saccharide isomerate provided by the invention can come from DSM in the Netherlands, has the trade name of PENTAVITIN and also called water-locking magnetite, has real moisture-retaining capacity on all areas of the face, can quickly recover the moisture content of extremely dry areas, and can deeply moisturize, smooth and soothe skin.
Example 1
The anti-aging firming and beautifying cream comprises the following components in percentage by mass:
Figure 49403DEST_PATH_IMAGE001
comparative example 1
The anti-aging firming and beautifying cream comprises the following components in percentage by mass:
Figure 248303DEST_PATH_IMAGE002
the preparation method of the anti-aging firming and beautifying cream described in the above examples and comparative examples comprises the following steps: (1) adding phase A into an emulsifying pot, heating to 80-85 deg.C, stirring and dissolving uniformly; (2) putting the phase B into an oil phase pot, and heating and dissolving to obtain an oil phase; (3) pumping the oil phase into an emulsifying pot under stirring, and starting homogenizing for 5-10 minutes; (4) adding the phase C into an emulsifying pot, uniformly stirring, and starting homogenizing for 3-5 minutes; (5) adding the phase D into an emulsifying pot, and stirring for 30 minutes under the condition of heat preservation; (6) cooling to 40-45 deg.C, adding phase E, and stirring.
Test 1 evaluation of efficacy
Test objects: 300 female volunteers of 35-60 years old were randomized into 10 groups of 30 individuals each. The facial fine lines of the testee are mild or moderate, the skin is slack or mild or moderate, the skin lacks elasticity, the tests can be well matched, and the life regularity is kept during the product trial period; all the contents of the informed consent can be read and understood and signed voluntarily; during the test period, other skin care products were discontinued, no further clinical trials were involved in any other research center, and no use of any cosmetics, drugs and nutraceuticals affecting the outcome was agreed to.
Test arrangement: 10 volunteers, 30 per group, were randomly grouped, using the working groups 1-5, comparative groups 1-5, respectively. After cleaning, 0.1g of the sample was taken and wiped on the facial skin, once in the morning and at night. Before, 4 weeks and 8 weeks after use, subjects washed their faces and rested for 30 min at a temperature of 21 + -1 deg.C and a relative humidity of 50% + -5% RH, collected data using a skin elastometer, a facial image analyzer VISIA, and examined for skin firmness and wrinkles.
(1) Skin firmness test.
The firmness of the facial skin was measured using a skin elastometer (Cutomer MPA 580) using a probe that repeated 3 measurements in the same area under test, and the average was taken. When the probe is used, the force is uniformly applied, and the applied pressure is constant. The skin firmness values of the test areas were measured again after 4 weeks, 8 weeks of use by the subjects. And finishing measurement, storing data, and sorting and analyzing the data.
R7 represents the ratio of the instantaneous springback Ur of the skin without negative pressure to the maximum stretch Uf with negative pressure, and represents the degree of compaction of the skin, with values closer to 1 being better.
Test results and evaluation: the data analysis of the skin firmness R7 before and after application of the product to the test area of the subject is shown in fig. 1 and fig. 2. Wherein the formula for calculating the rate of change of R7 is: r7 change rate% = (week R7 value-week 0R 7 value)/week 0R 7 value 100%.
As can be seen from FIG. 1, the skin firmness changes tested in the practice groups 1-5 gradually increased with increasing product application time. Compared with the comparison groups 1-5, the implementation groups 1-5 can obtain that the four anti-aging components in the anti-aging firming beauty cream are more beneficial to enhancing the skin firmness in a synergistic manner, and can realize more obvious anti-aging effect.
As can be seen from FIG. 2, the skin firmness of the subjects in the examples 1 to 5 was significantly increased, and the skin firmness was significantly different between the examples 1 to 5 and the comparative examples 1 to 5 after 4 weeks and 8 weeks of use.
(2) Skin wrinkle feature count test.
The instrument comprises the following steps: skin rapid optical imaging system VISIA facial image analyzer. And (3) wrinkle feature counting: the smaller the number of facial wrinkles, which indicates the lower the number of facial skin wrinkles. Wrinkle score: the smaller the numerical value of the facial wrinkles, which reflects the size, area and density of the facial wrinkles, indicates the smaller the size, area and density of the facial wrinkles.
Test results and evaluation: analysis of test data for skin wrinkle characteristic counts before and after product application to the subject area is shown in figures 3 and 4. Wherein, the wrinkle feature count change rate% = (wrinkle feature count at test week-wrinkle feature count at week 0)/wrinkle feature count at week 0 = 100%.
As can be seen from fig. 3 and 4: the skin wrinkle characteristic counts of the subjects of the working groups 1 to 5 and the comparative groups 1 to 5 were decreased at 4 weeks and 8 weeks with the use time, and the wrinkle characteristic counts and the wrinkle scores were more significantly decreased at 8 weeks. And the reduction in the number, size, area and density of wrinkles was more significant in the examples 1 to 5 than in the comparative examples 1 to 5. Compared with the comparison groups 1-5, the implementation groups 1-5 can obtain that the four anti-aging components in the anti-aging firming beauty cream are more beneficial to reducing wrinkles in a synergistic manner, and can realize more obvious anti-aging effect.
Experiment 2 safety test
150 volunteers with age of 35-60, obvious facial wrinkles and poor skin elasticity are selected and divided into 5 groups, 30 persons in each group are selected, a standard spot tester (Beijing Yida) is selected, about 0.020-0.025g of a test object is placed in a small chamber of the spot tester by a closed spot test method, the test object is pasted in the arm of a subject for testing, the spot tester is removed after 24 hours, skin reactions are observed at 0.5 hour, 6 hours, 12 hours, 24 hours and 48 hours respectively, and the results are recorded according to the skin reaction grading standard in technical Specification for safety of cosmetics (2015 edition). In 30 subjects, the number of people with grade 1 adverse skin reactions is more than 5, the number of people with grade 2 adverse skin reactions is more than 2 (the number of people with grade 2 reactions in a deodorization product patch test is more than 5), or any 1 case with grade 3 or more than 3 adverse skin reactions occurs, and the subjects are judged to have adverse skin reactions on human bodies. Specific criteria can be found in table 1 below.
TABLE 1 skin reaction grade index table for skin-enclosed patch test
Figure 979499DEST_PATH_IMAGE003
And (3) testing results: the reaction condition of the beauty cream group on human skin is evaluated according to the patch result, and then the grading is carried out according to the degree grade of the table 1, and the specific result is detailed in the table 2:
TABLE 2 volunteer Patch test data sheet (48 hours later observation)
Figure 972862DEST_PATH_IMAGE004
As can be seen from Table 2, all volunteers observed skin reactions for 48 hours through the patch tests of the working groups 1 to 5 described in the present invention, of which 0 cases showed skin adverse reactions, indicating that the samples of the working groups 1 to 5 described in the present invention were safe.
The above description is only a preferred embodiment of the present invention, and is not intended to limit the present invention in any way, so that any simple modification, equivalent change and modification made to the above embodiment according to the technical spirit of the present invention will still fall within the scope of the technical solution of the present invention without departing from the content of the technical solution of the present invention.

Claims (10)

1. An anti-aging firming beauty cream containing kangaroo paw extract is characterized by mainly comprising the following components in percentage by weight:
0.2-2.0% of kangaroo paw (ANIGOZANTHOS FLAVIDUS) extract,
0.01 to 0.2 percent of ergothioneine,
1.0-5.0% of 1 ‰ aqueous solution of acetyl octapeptide-3,
Carnosine 0.01-0.2%.
2. The anti-aging firming skin-care cream containing the kangaroo paw extract as claimed in claim 1, is characterized by further comprising the following components in percentage by weight:
0.1-1.0% of extract of flos Buddlejae (Buddleja OFFICINALIS),
0.1-0.4% of glycosphingolipids,
Saccharide isomerate 0.1-0.5%.
3. The anti-aging firming skin-care cream containing the kangaroo paw extract as claimed in claim 1, is characterized by further comprising the following components in percentage by weight: 2.8 to 5.1 percent of emulsifier, 5.65 to 15.25 percent of emollient, 4.5 to 13.0 percent of polyol, 1.48 to 4.0 percent of thickening stabilizer, 1.0 percent of antibacterial agent, 0.3 to 1.2 percent of anti-allergy agent and 0.09 to 0.21 percent of pH value regulator.
4. The cream of claim 3, wherein the emollient comprises glycerol tri (ethyl hexanoate), dimethicone, isononyl isononanoate, theobroma grandiflora (theobroma randylorus) seed fat, tocopherol acetate, jojoba (SIMMONDSIA CHINENSIS) seed oil, wherein the ratio of the mass of glycerol tri (ethyl hexanoate), dimethicone, isononyl isononanoate, theobroma grandiflora (theobroma randylorus) seed fat, tocopherol acetate, jojoba (SIMMONDSIA CHINENSIS) seed oil is (2.0-5.0): (2.0-4.0): (1.0-4.0):(0.1-1.0):(0.15-0.25):(0.4-1.0).
5. The cream as claimed in claim 3, wherein the polyhydric alcohol comprises glycerol, butylene glycol and PPG-24-glyceryl polyether-24, and the mass ratio of glycerol, butylene glycol and PPG-24-glyceryl polyether-24 is (2.0-6.0): 2.0-6.0: 0.5-1.0.
6. The cream as claimed in claim 3, wherein the thickening stabilizer is a mixture of carbomer, xanthan gum, cetostearyl alcohol and SIMULGEL EG, and the mass ratio of carbomer, xanthan gum, cetostearyl alcohol and SIMULGEL EG is (0.15-0.35) to (0.03-0.15): (0.8-2.0): (0.5-1.5).
7. The cream as claimed in claim 3, wherein the antibacterial agent is a mixture of p-hydroxyacetophenone and 1, 2-hexanediol, and the mass ratio of p-hydroxyacetophenone to 1, 2-hexanediol is (0.5-0.55) to (0.45-0.5).
8. The anti-aging firming and beautifying cream containing kangaroo paw extract as claimed in claim 3, wherein the anti-allergy agent is composed of hydroxyphenylpropionamide benzoic acid and panthenol, and the mass ratio of the hydroxyphenylpropionamide benzoic acid to the panthenol is (0.1-0.2) to (0.2-1.0).
9. The anti-aging firming cream containing the kangaroo paw extract as claimed in claim 3, wherein the emulsifier is composed of cetearyl alcohol/cetearyl glucoside, cetearyl olive oleate/sorbitan olive oleate, glyceryl stearate/PEG-100 stearate, and the mass ratio of cetearyl alcohol/cetearyl glucoside, cetearyl olive oleate/sorbitan olive oleate, glyceryl stearate/PEG-100 stearate is (1.5-2.6): (0.8-2.5): (0.5-1.0).
10. The anti-aging firming skin-care cream containing the kangaroo paw extract as claimed in claim 1, is characterized by further comprising the following components in percentage by weight: 0.001-0.01% of ROSA DAMASCENA (ROSA DAMASCENA) flower oil, 0.01-0.05% of disodium EDTA, 0.1-0.2% of allantoin and 0.2-1.0% of trehalose.
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113318056A (en) * 2021-05-28 2021-08-31 广州伊尔美生物科技有限公司 New-born beautifying, firming and wrinkle-removing composition, preparation method thereof and firming and wrinkle-removing cream
CN115025010A (en) * 2021-03-04 2022-09-09 新生活化妆品科技(上海)有限公司 Application of kangaroo paw extract and cosmetic composition for improving expression lines
WO2024035908A1 (en) * 2022-08-12 2024-02-15 Colgate-Palmolive Company Personal care compositions

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110305737A1 (en) * 2010-06-09 2011-12-15 NY Derm LLC Multi-Active Microtargeted Anti-Aging Skin Cream Polymer Technology
US20160235661A1 (en) * 2015-02-16 2016-08-18 Axim Biotechnologies, Inc. Cosmetic and topical compositions comprising cannabigerol
CN105919908A (en) * 2016-04-20 2016-09-07 广州雷诺生物科技有限公司 Skin soothing regenerating protein film cream and preparation method thereof
CN106798722A (en) * 2015-11-26 2017-06-06 上海优莱美生物科技有限公司 A kind of anti-ageing moisturizing maintenance creams of not silicate-containing oil and preparation method thereof
CN107411997A (en) * 2017-06-26 2017-12-01 上海新高姿化妆品有限公司 A kind of anti-aging face cream composition
CN109937031A (en) * 2016-10-17 2019-06-25 国际香料香精公司 Kangaroo pawl extract for beautifying use
CN109939027A (en) * 2019-03-01 2019-06-28 华熙生物科技股份有限公司 A kind of method of cosmetics stoste of the Hericium erinaceus fermentation preparation containing erythrothioneine

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110305737A1 (en) * 2010-06-09 2011-12-15 NY Derm LLC Multi-Active Microtargeted Anti-Aging Skin Cream Polymer Technology
US20160235661A1 (en) * 2015-02-16 2016-08-18 Axim Biotechnologies, Inc. Cosmetic and topical compositions comprising cannabigerol
CN106798722A (en) * 2015-11-26 2017-06-06 上海优莱美生物科技有限公司 A kind of anti-ageing moisturizing maintenance creams of not silicate-containing oil and preparation method thereof
CN105919908A (en) * 2016-04-20 2016-09-07 广州雷诺生物科技有限公司 Skin soothing regenerating protein film cream and preparation method thereof
CN109937031A (en) * 2016-10-17 2019-06-25 国际香料香精公司 Kangaroo pawl extract for beautifying use
CN107411997A (en) * 2017-06-26 2017-12-01 上海新高姿化妆品有限公司 A kind of anti-aging face cream composition
CN109939027A (en) * 2019-03-01 2019-06-28 华熙生物科技股份有限公司 A kind of method of cosmetics stoste of the Hericium erinaceus fermentation preparation containing erythrothioneine

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
陪冈: "《带着我去化妆台柜台》", 31 December 2009, 新世界出版社 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115025010A (en) * 2021-03-04 2022-09-09 新生活化妆品科技(上海)有限公司 Application of kangaroo paw extract and cosmetic composition for improving expression lines
CN113318056A (en) * 2021-05-28 2021-08-31 广州伊尔美生物科技有限公司 New-born beautifying, firming and wrinkle-removing composition, preparation method thereof and firming and wrinkle-removing cream
WO2024035908A1 (en) * 2022-08-12 2024-02-15 Colgate-Palmolive Company Personal care compositions

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