CN110709090A - 用于在体内递送治疗剂的b细胞及其剂量 - Google Patents

用于在体内递送治疗剂的b细胞及其剂量 Download PDF

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Publication number
CN110709090A
CN110709090A CN201880037089.5A CN201880037089A CN110709090A CN 110709090 A CN110709090 A CN 110709090A CN 201880037089 A CN201880037089 A CN 201880037089A CN 110709090 A CN110709090 A CN 110709090A
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cells
genetically modified
cell
subject
composition
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马修·瑞恩·舒尔茨
埃里克·J·赫比格
斯科特·R·麦基弗
里安·德拉特
埃里克·奥尔森
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Yimusovt Co
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CN201880037089.5A 2017-04-27 2018-04-27 用于在体内递送治疗剂的b细胞及其剂量 Pending CN110709090A (zh)

Applications Claiming Priority (3)

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US201762491151P 2017-04-27 2017-04-27
US62/491,151 2017-04-27
PCT/US2018/029993 WO2018201071A1 (en) 2017-04-27 2018-04-27 B cells for in vivo delivery of therapeutic agents and dosages thereof

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US (1) US20220193129A1 (enExample)
EP (1) EP3615045A4 (enExample)
JP (3) JP2020517692A (enExample)
CN (1) CN110709090A (enExample)
AU (2) AU2018256887B2 (enExample)
BR (1) BR112019022473A2 (enExample)
CA (1) CA3061048A1 (enExample)
WO (1) WO2018201071A1 (enExample)

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US12440513B2 (en) 2019-03-22 2025-10-14 Albany Medical College Methods for improving cognitive function
CN110499336B (zh) * 2019-08-23 2021-10-12 华南农业大学 一种利用小分子化合物提高基因组定点修饰效率的方法
JP2023548118A (ja) * 2020-10-30 2023-11-15 イミュソフト コーポレーション 治療剤のin vivo送達のために、遺伝子改変B細胞を投与する方法
TW202309270A (zh) * 2021-04-19 2023-03-01 美商步行魚醫療公司 用於細胞療法的b細胞擴增之方法
WO2024044697A2 (en) * 2022-08-24 2024-02-29 Walking Fish Therapeutics, Inc. Compositions and methods for treatment of fabry disease
WO2024220447A2 (en) * 2023-04-17 2024-10-24 Be Biopharma, Inc. Engineered cell preparations for treatment of niemann pick b disease
AU2024257819A1 (en) * 2023-04-17 2025-10-23 Be Biopharma, Inc. Engineered cell preparations for treatment of hemophilia
US20250152714A1 (en) 2023-11-15 2025-05-15 Immusoft Corporation Migratory modified differentiated b cells for cancer therapy

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AU2016202625A1 (en) * 2007-07-27 2016-05-19 Armagen Technologies, Inc. Methods and compositions for increasing alpha-iduronidase activity in the CNS
WO2016100932A1 (en) * 2014-12-19 2016-06-23 Immusoft Corporation B cells for in vivo delivery of therapeutic agents
WO2016161446A1 (en) * 2015-04-03 2016-10-06 Dana-Farber Cancer Institute, Inc. Composition and methods of genome editing of b-cells
CN106103489A (zh) * 2014-01-27 2016-11-09 分子模板公司 Mhc i类表位递送多肽
WO2016187017A1 (en) * 2015-05-15 2016-11-24 Mcivor R Scott Adeno-associated for therapeutic delivery to central nervous system

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EP2029165B1 (en) * 2006-04-27 2014-12-03 Cellid Co., Ltd B cell-based vaccine loaded with the ligand of natural killer t cell and antigen
WO2011085247A2 (en) * 2010-01-08 2011-07-14 Immusoft Corporation Vectors and methods for transducing b cells
EP2971039B1 (en) * 2013-03-14 2020-01-01 Immusoft Corporation Methods for in vitro memory b cell differentiation and transduction with vsv-g pseudotyped viral vectors
JP2021515576A (ja) * 2018-03-16 2021-06-24 イミュソフト コーポレーション フォリスタチンを分泌するように遺伝子操作されたb細胞ならびにフォリスタチン関連疾患、状態、障害を処置するために、ならびに筋肉の成長および強度を増強するためにこれを使用する方法

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Publication number Priority date Publication date Assignee Title
AU2016202625A1 (en) * 2007-07-27 2016-05-19 Armagen Technologies, Inc. Methods and compositions for increasing alpha-iduronidase activity in the CNS
CN106103489A (zh) * 2014-01-27 2016-11-09 分子模板公司 Mhc i类表位递送多肽
WO2016100932A1 (en) * 2014-12-19 2016-06-23 Immusoft Corporation B cells for in vivo delivery of therapeutic agents
WO2016161446A1 (en) * 2015-04-03 2016-10-06 Dana-Farber Cancer Institute, Inc. Composition and methods of genome editing of b-cells
WO2016187017A1 (en) * 2015-05-15 2016-11-24 Mcivor R Scott Adeno-associated for therapeutic delivery to central nervous system

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JP2020517692A (ja) 2020-06-18
WO2018201071A1 (en) 2018-11-01
US20220193129A1 (en) 2022-06-23
JP7526312B2 (ja) 2024-07-31
EP3615045A1 (en) 2020-03-04
RU2019136194A3 (enExample) 2021-08-02
AU2025202508A1 (en) 2025-06-05
AU2018256887B2 (en) 2025-01-09
CA3061048A1 (en) 2018-11-01
JP2023093703A (ja) 2023-07-04
AU2018256887A1 (en) 2019-11-07
JP2024153703A (ja) 2024-10-29
RU2019136194A (ru) 2021-05-27
BR112019022473A2 (pt) 2020-10-20
EP3615045A4 (en) 2021-01-13

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