CN110709090A - 用于在体内递送治疗剂的b细胞及其剂量 - Google Patents

用于在体内递送治疗剂的b细胞及其剂量 Download PDF

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Publication number
CN110709090A
CN110709090A CN201880037089.5A CN201880037089A CN110709090A CN 110709090 A CN110709090 A CN 110709090A CN 201880037089 A CN201880037089 A CN 201880037089A CN 110709090 A CN110709090 A CN 110709090A
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cells
genetically modified
cell
subject
composition
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Chinese (zh)
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马修·瑞恩·舒尔茨
埃里克·J·赫比格
斯科特·R·麦基弗
里安·德拉特
埃里克·奥尔森
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Yimusovt Co
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Yimusovt Co
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CN201880037089.5A 2017-04-27 2018-04-27 用于在体内递送治疗剂的b细胞及其剂量 Pending CN110709090A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762491151P 2017-04-27 2017-04-27
US62/491,151 2017-04-27
PCT/US2018/029993 WO2018201071A1 (en) 2017-04-27 2018-04-27 B cells for in vivo delivery of therapeutic agents and dosages thereof

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CN110709090A true CN110709090A (zh) 2020-01-17

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US (1) US20220193129A1 (cg-RX-API-DMAC10.html)
EP (1) EP3615045A4 (cg-RX-API-DMAC10.html)
JP (3) JP2020517692A (cg-RX-API-DMAC10.html)
CN (1) CN110709090A (cg-RX-API-DMAC10.html)
AU (2) AU2018256887B2 (cg-RX-API-DMAC10.html)
BR (1) BR112019022473A2 (cg-RX-API-DMAC10.html)
CA (1) CA3061048A1 (cg-RX-API-DMAC10.html)
WO (1) WO2018201071A1 (cg-RX-API-DMAC10.html)

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KR102559149B1 (ko) 2018-10-26 2023-07-24 에프. 호프만-라 로슈 아게 재조합효소 매개 카세트 교환을 이용한 다중특이적 항체 스크리닝 방법
US12440513B2 (en) 2019-03-22 2025-10-14 Albany Medical College Methods for improving cognitive function
CN110499336B (zh) * 2019-08-23 2021-10-12 华南农业大学 一种利用小分子化合物提高基因组定点修饰效率的方法
WO2021108650A1 (en) * 2019-11-27 2021-06-03 Board Of Regents, The University Of Texas System Large-scale combined car transduction and crispr gene editing of b cells
WO2022094284A1 (en) * 2020-10-30 2022-05-05 Immusoft Corporation Methods of administering genetically modified b cells for in vivo delivery of therapeutic agents
KR20240024781A (ko) * 2021-04-19 2024-02-26 워킹 피쉬 테라퓨틱스 인코포레이티드 세포 요법에 사용하기 위한 b 세포 확장의 방법
TW202423959A (zh) * 2022-08-24 2024-06-16 美商步行魚醫療公司 用於治療法布瑞氏症(fabry disease)之組成物及方法
WO2024220447A2 (en) * 2023-04-17 2024-10-24 Be Biopharma, Inc. Engineered cell preparations for treatment of niemann pick b disease
KR20250175332A (ko) * 2023-04-17 2025-12-16 비이 바이오파마, 인크. 혈우병 치료를 위한 조작된 세포 제제
US20250152714A1 (en) 2023-11-15 2025-05-15 Immusoft Corporation Migratory modified differentiated b cells for cancer therapy
WO2026085108A2 (en) 2024-10-14 2026-04-23 Immusoft Corporation B cell compositions and methods of use

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AU2016202625A1 (en) * 2007-07-27 2016-05-19 Armagen Technologies, Inc. Methods and compositions for increasing alpha-iduronidase activity in the CNS
WO2016100932A1 (en) * 2014-12-19 2016-06-23 Immusoft Corporation B cells for in vivo delivery of therapeutic agents
WO2016161446A1 (en) * 2015-04-03 2016-10-06 Dana-Farber Cancer Institute, Inc. Composition and methods of genome editing of b-cells
CN106103489A (zh) * 2014-01-27 2016-11-09 分子模板公司 Mhc i类表位递送多肽
WO2016187017A1 (en) * 2015-05-15 2016-11-24 Mcivor R Scott Adeno-associated for therapeutic delivery to central nervous system

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BRPI0621599B1 (pt) * 2006-04-27 2021-07-27 Cellid Co., Ltd Vacina baseada em células b carregadas com o ligante da célula t exterminadora natural e antígeno
DK2521789T3 (en) * 2010-01-08 2017-03-27 Immusoft Corp VECTORS AND PROCEDURE FOR B-CELL TRANSDUCTION
ES2786253T3 (es) * 2013-03-14 2020-10-09 Immusoft Corp Métodos para la diferenciación y transducción in vitro de células b de memoria con vectores virales pseudotipados vsv-g
CA3093716A1 (en) * 2018-03-16 2019-09-19 Immusoft Corporation B cells genetically engineered to secrete follistatin and methods of using the same to treat follistatin-related diseases, conditions, disorders and to enhance muscle growth and strength

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AU2016202625A1 (en) * 2007-07-27 2016-05-19 Armagen Technologies, Inc. Methods and compositions for increasing alpha-iduronidase activity in the CNS
CN106103489A (zh) * 2014-01-27 2016-11-09 分子模板公司 Mhc i类表位递送多肽
WO2016100932A1 (en) * 2014-12-19 2016-06-23 Immusoft Corporation B cells for in vivo delivery of therapeutic agents
WO2016161446A1 (en) * 2015-04-03 2016-10-06 Dana-Farber Cancer Institute, Inc. Composition and methods of genome editing of b-cells
WO2016187017A1 (en) * 2015-05-15 2016-11-24 Mcivor R Scott Adeno-associated for therapeutic delivery to central nervous system

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WO2018201071A1 (en) 2018-11-01
JP2020517692A (ja) 2020-06-18
AU2018256887A1 (en) 2019-11-07
AU2025202508A1 (en) 2025-06-05
JP2023093703A (ja) 2023-07-04
CA3061048A1 (en) 2018-11-01
RU2019136194A (ru) 2021-05-27
JP2024153703A (ja) 2024-10-29
EP3615045A1 (en) 2020-03-04
NZ758331A (en) 2025-12-19
US20220193129A1 (en) 2022-06-23
JP7526312B2 (ja) 2024-07-31
EP3615045A4 (en) 2021-01-13
BR112019022473A2 (pt) 2020-10-20
AU2018256887B2 (en) 2025-01-09
RU2019136194A3 (cg-RX-API-DMAC10.html) 2021-08-02

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