CN110709085A - 治疗内脏疼痛的化合物和方法 - Google Patents
治疗内脏疼痛的化合物和方法 Download PDFInfo
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- CN110709085A CN110709085A CN201880037898.6A CN201880037898A CN110709085A CN 110709085 A CN110709085 A CN 110709085A CN 201880037898 A CN201880037898 A CN 201880037898A CN 110709085 A CN110709085 A CN 110709085A
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- tetrahydro
- diaza
- carboxylic acid
- amide
- cyclopropa
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- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
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- A—HUMAN NECESSITIES
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- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| WO2023150648A2 (en) * | 2022-02-02 | 2023-08-10 | Makscientific, Llc | Pharmaceutical compositions, and preparation and methods of use thereof |
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| CN102596913A (zh) * | 2009-08-28 | 2012-07-18 | 艾尼纳制药公司 | 大麻素受体调节剂 |
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2018
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- 2018-05-08 MA MA048625A patent/MA48625A/fr unknown
- 2018-05-08 CN CN201880037898.6A patent/CN110709085A/zh active Pending
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| EP3621619B1 (en) | 2023-06-28 |
| CA3062824A1 (en) | 2018-11-15 |
| MX2019013311A (es) | 2020-08-03 |
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| US20230033510A1 (en) | 2023-02-02 |
| WO2018208848A1 (en) | 2018-11-15 |
| US12201633B2 (en) | 2025-01-21 |
| MX2022008265A (es) | 2022-08-04 |
| KR20200005614A (ko) | 2020-01-15 |
| BR112019023214A2 (pt) | 2020-05-26 |
| US20200078358A1 (en) | 2020-03-12 |
| EA201992638A1 (ru) | 2020-03-18 |
| EP3621619A1 (en) | 2020-03-18 |
| EP3621619C0 (en) | 2023-06-28 |
| JP2020518649A (ja) | 2020-06-25 |
| JP7247106B2 (ja) | 2023-03-28 |
| AU2018266145A1 (en) | 2019-11-28 |
| MA48625A (fr) | 2020-03-18 |
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