CN110694022A - A patch for treating sole heart with blood pressure and blood lipid lowering effects, and its preparation method - Google Patents
A patch for treating sole heart with blood pressure and blood lipid lowering effects, and its preparation method Download PDFInfo
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- CN110694022A CN110694022A CN201911025393.0A CN201911025393A CN110694022A CN 110694022 A CN110694022 A CN 110694022A CN 201911025393 A CN201911025393 A CN 201911025393A CN 110694022 A CN110694022 A CN 110694022A
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Abstract
The invention discloses a sole heart paste with the functions of reducing blood pressure and blood fat, wherein the formula of the sole heart paste with the functions of reducing blood pressure and blood fat is as follows according to 100 mass components: 1-5 g of fructus evodiae, 25-35 g of eclipta alba, 30-50 g of purslane, 40-60 g of selfheal, 25-35 g of uncaria, 10-20 g of achyranthes bidentata, 5-10 g of rhizoma sparganii, 15-25 g of gallnut, 5-10 g of liquorice and 250-350 g of corn stigma. The invention also discloses a preparation method of the plantar region patch with the functions of reducing blood pressure and blood fat. The invention can achieve the purpose of reducing blood pressure and blood fat, can eliminate various diseases caused by hypertension and hyperlipidemia, achieves the purpose of treating both principal and secondary aspects of disease, adopts the process of combining the high-pressure decocting device and the copper pot, has the advantages of high preparation efficiency and simple production, and is easy for industrial production.
Description
Technical Field
The invention relates to the technical field of ointment, in particular to a plantar region patch with the functions of reducing blood pressure and blood fat, and also relates to a preparation method of the plantar region patch with the functions of reducing blood pressure and blood fat.
Background
With the improvement of living standard and the change of life rhythm, people have excessive lipid and alcohol in the diet and are called as 'hypertension, hyperglycemia and hyperlipidemia' which are rich and precious, and particularly common diseases of the health of middle-aged and elderly people over 50 years old. Cardiovascular and cerebrovascular diseases become the first killer with the highest cause of human death, and are also the silent and violent reasons for human health. And can cause serious cardiovascular and cerebrovascular complications, such as coronary heart disease, myocardial infarction, renal failure, apoplexy, hemiplegia, and heart failure, which seriously harm life and health.
At present, the medicines for treating hypertension and hyperlipidemia are various in varieties, mainly oral medicines, generally have large toxic and side effects, and can cause liver and kidney and other organ injuries.
Disclosure of Invention
The invention aims to provide a plantar arch patch with the functions of reducing blood pressure and blood fat and a preparation method thereof, which can achieve the aims of reducing blood pressure and blood fat, can eliminate various diseases caused by hypertension and hyperlipidemia and achieve the aim of treating both principal and secondary aspects of disease.
In order to achieve the purpose, the invention provides the following technical scheme:
the plantar region patch with the functions of reducing blood pressure and blood fat comprises the following components in parts by mass per 100:
1-5 g of fructus evodiae, 25-35 g of eclipta alba, 30-50 g of purslane, 40-60 g of selfheal, 25-35 g of uncaria, 10-20 g of achyranthes bidentata, 5-10 g of rhizoma sparganii, 15-25 g of gallnut, 5-10 g of liquorice and 250-350 g of corn stigma.
The invention also provides a preparation method of the arch patch with the functions of reducing blood pressure and blood fat, which comprises the following steps:
s1, weighing fructus evodiae, eclipta alba, purslane, selfheal, uncaria, achyranthes bidentata, rhizoma sparganii, gallnut, liquorice and corn stigma according to a proper mass ratio;
s2, removing impurities in fructus evodiae, eclipta alba, purslane, selfheal, uncaria, achyranthes bidentata, rhizoma sparganii, gallnut, liquorice and corn stigma weighed in the S1, wrapping the impurities by using a gauze bag, soaking the wrapped gauze bag in clear water for 3-5 hours, then washing the gauze bag in an ultrasonic washing machine, drying the gauze bag by using a drying machine after washing, and putting the gauze bag in the dried gauze bag, so that the gauze bag can be soaked thoroughly and can be taken out conveniently, and the medicinal materials can fully exert curative effects in the decocting process;
s3, putting the dried fructus evodiae, eclipta alba, purslane, selfheal, uncaria, achyranthes bidentata, rhizoma sparganii, gallnut, liquorice and corn stigma in the S2 into a high-pressure decocting device, adding purified water, decocting for three times, filtering out filtrates respectively, and combining the filtrates for three times;
s4, adding the filtrate obtained in the step S3 into a copper pot, adding the malt extract with the volume of 1/50, and stirring and mixing for 10-20 min through an electric stirrer;
s5, erecting the copper pot in the S4 on a stove, decocting for 8-12 hours, and continuously stirring through an electric stirrer to obtain paste;
s6, putting the paste obtained in the step S5 into a vacuum concentration tank, and concentrating under reduced pressure to obtain a paste with the relative density of 1.2-1.3;
s7, sterilizing the paste obtained in the step S6, and then filling the sterilized paste into a packaging bottle for wax sealing storage;
s8, pouring out the paste in the step S7, adding inula flower liquid with the volume of the paste 1/50, uniformly mixing, and coating the mixture on a medicinal patch to obtain the plantar region patch with the effects of reducing blood pressure and blood fat.
Preferably, the frequency of the ultrasonic cleaning machine in the S2 is set to be 40-60 KHz, the cleaning time is 5-10 min, and the temperature is set to be 55-65 ℃.
Preferably, the specific method for decocting in water in S3 is as follows:
adding purified water with the volume 4 times that of the medicinal materials into a high-pressure decocting device for first decocting, wherein the decocting time is 60-80 min, and filtering to obtain primary filter residue;
adding purified water with the volume 3 times that of the primary filter residue into a high-pressure decocting device for second decocting, wherein the decocting time is 40-60 min, and filtering to obtain secondary filter residue;
adding purified water with 2 times of volume of the secondary filter residue into a high-pressure decocting device for third decocting, wherein the decocting time is 30-40 min, and filtering.
Preferably, the high-pressure boiler in S3 is heated by steam, and the water is boiled in only 5 minutes by heating with steam, and the medicinal liquid is slowly boiled for the rest time, so that the medicinal materials are fully fused with each other, and the efficiency is higher.
Preferably, the stirring speed of the electric stirrer in S4 is 120-200 r/min, and the stirring speed of the electric stirrer in S5 is 60-80 r/min.
Preferably, the sterilization in S7 is to perform far infrared ray irradiation disinfection sterilization by raising the temperature to 155-165 ℃.
Preferably, the packaging bottle in the S7 is a glass bottle.
Compared with the prior art, the invention has the beneficial effects that: the plantar region patch with the functions of reducing blood pressure and blood fat provided by the invention has reasonable component proportion, is externally applied to the plantar region in a mode of a plaster patch, enters the human body through plantar acupoints, dredges the channels and collaterals, adjusts viscera, balances yin and yang, and nourishes the liver and kidney, so that the aim of reducing blood pressure and blood fat is achieved, various diseases caused by the high blood pressure and the high blood fat can be eliminated, the high blood pressure and the high blood fat can be fundamentally relieved, the blood pressure and the blood fat are stable, the blood pressure and the blood fat do not rise again after being reduced, the pain of taking the medicine for a long time is solved, the plantar region patch has the advantages of short treatment course, quick response, no toxic or side effect, no damage to other viscera, convenience in use, low price and difficulty in relapse after healing, and the aim of simultaneous treatment of principal and subordinate symptoms is achieved, the preparation method of the plantar region patch with the functions of reducing blood pressure and blood fat is simple, has the advantages of high preparation efficiency and simple production, and is easy for industrialized production.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the following embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
The base material composition data of the plantar region patch with the functions of reducing blood pressure and blood fat provided by the invention are as follows:
| base material composition | Example 1 (parts) | Example 2 (parts) | Example 3 (parts) |
| Evodia rutaecarpa | 1 | 3 | 5 |
| Herba Ecliptae | 40 | 50 | 60 |
| Purslane herb | 30 | 40 | 50 |
| Selfheal | 1 | 3 | 5 |
| Ramulus Uncariae cum uncis | 25 | 30 | 35 |
| Radix achyranthis bidentatae | 10 | 15 | 20 |
| Triangular prism | 5 | 8 | 10 |
| Galla chinensis | 15 | 20 | 25 |
| Licorice root, radix Glycyrrhizae | 5 | 8 | 10 |
| Corn silk | 250 | 300 | 350 |
Example 1
The plantar region patch with the functions of reducing blood pressure and blood fat comprises the following components in parts by mass per 100:
1g of fructus evodiae, 25g of herba ecliptae, 30g of herba portulacae, 40g of selfheal, 25g of uncaria, 10g of radix achyranthis bidentatae, 5g of rhizoma sparganii, 15g of gallnut, 5g of liquorice and 250g of corn stigma.
The invention also provides a preparation method of the arch patch with the functions of reducing blood pressure and blood fat, which comprises the following steps:
s1, weighing fructus evodiae, eclipta alba, purslane, selfheal, uncaria, achyranthes bidentata, rhizoma sparganii, gallnut, liquorice and corn stigma according to a proper mass ratio;
s2, removing impurities in fructus evodiae, eclipta alba, purslane, selfheal, uncaria, achyranthes bidentata, rhizoma sparganii, gallnut, liquorice and corn stigma weighed in S1, wrapping the impurities with a gauze bag, soaking the wrapped gauze bag in clear water for 3 hours, then putting the gauze bag into an ultrasonic cleaning machine for cleaning, and drying the gauze bag in a drying machine after cleaning, wherein the frequency of the ultrasonic cleaning machine is set to be 40KHz, the cleaning time is 5min, and the temperature is set to be 55 ℃;
s3, putting the dried fructus evodiae, eclipta alba, purslane, selfheal, uncaria, achyranthes bidentata, rhizoma sparganii, gallnut, liquorice and corn stigma in the S2 into a high-pressure decocting device, heating the high-pressure decocting device through steam, adding purified water, decocting the mixture for three times, respectively filtering out filtrates, and combining the filtrates;
the specific method for decocting in water comprises the following steps:
adding purified water with 4 times volume of the medicinal materials into a high-pressure decocting device for first decocting for 60min, and filtering to obtain first residue;
adding purified water with volume 3 times of that of the primary filter residue into a high-pressure decocting device for decocting for a second time, wherein the decocting time is 40min, and filtering to obtain secondary filter residue;
adding purified water with 2 times volume of the secondary filter residue into a high-pressure decocting device for decocting for the third time, wherein the decocting time is 30min, and filtering;
s4, adding the filtrate obtained in the step S3 into a copper pot, adding the malt extract with the volume of 1/50, and stirring and mixing for 10min by an electric stirrer at the stirring speed of 120 r/min;
s5, erecting the copper pot in the step S4 on a stove for boiling for 8 hours, and meanwhile, continuously stirring by an electric stirrer at the stirring speed of 60r/min to obtain paste;
s6, putting the paste obtained in the step S5 into a vacuum concentration tank, and concentrating under reduced pressure to obtain a paste with the relative density of 1.2;
s7, sterilizing the paste obtained in S6, then filling the paste into a glass bottle, sealing with wax and storing, wherein the sterilization is to perform far infrared ray irradiation disinfection sterilization when the temperature is raised to 155 ℃;
s8, pouring out the paste in the step S7, adding inula flower liquid with the volume of the paste 1/50, uniformly mixing, and coating the mixture on a medicinal patch to obtain the plantar region patch with the effects of reducing blood pressure and blood fat.
Example 2
The plantar region patch with the functions of reducing blood pressure and blood fat comprises the following components in parts by mass per 100:
3g of fructus evodiae, 30g of herba ecliptae, 40g of summer purslane, 50g of selfheal, 30g of uncaria, 15g of radix achyranthis bidentatae, 8g of rhizoma sparganii, 20g of gallnut, 8g of liquorice and 300g of corn stigma.
The invention also provides a preparation method of the arch patch with the functions of reducing blood pressure and blood fat, which comprises the following steps:
s1, weighing fructus evodiae, eclipta alba, purslane, selfheal, uncaria, achyranthes bidentata, rhizoma sparganii, gallnut, liquorice and corn stigma according to a proper mass ratio;
s2, removing impurities in fructus evodiae, eclipta alba, purslane, selfheal, uncaria, achyranthes bidentata, rhizoma sparganii, gallnut, liquorice and corn stigma weighed in the S1, wrapping the impurities with a gauze bag, soaking the wrapped gauze bag in clear water for 4 hours, then cleaning the gauze bag in an ultrasonic cleaning machine, and drying the gauze bag in a drying machine after cleaning, wherein the frequency of the ultrasonic cleaning machine is set to be 50KHz, the cleaning time is 8min, and the temperature is set to be 60 ℃;
s3, putting the dried fructus evodiae, eclipta alba, purslane, selfheal, uncaria, achyranthes bidentata, rhizoma sparganii, gallnut, liquorice and corn stigma in the S2 into a high-pressure decocting device, heating the high-pressure decocting device through steam, adding purified water, decocting the mixture for three times, respectively filtering out filtrates, and combining the filtrates;
the specific method for decocting in water comprises the following steps:
adding purified water with 4 times volume of the medicinal materials into a high-pressure decocting device for decocting for 70min, and filtering to obtain primary filter residue;
adding purified water with volume 3 times of that of the primary filter residue into a high-pressure decocting device for decocting for 50min for the second time, and filtering to obtain secondary filter residue;
adding purified water with 2 times volume of the secondary filter residue into a high-pressure decocting device for third decocting, wherein the decocting time is 35min, and filtering;
s4, adding the filtrate obtained in the step S3 into a copper pot, adding the wheat glue with the volume of 1/50 into the copper pot, and stirring and mixing the mixture for 15min by using an electric stirrer, wherein the stirring speed is 160 r/min;
s5, erecting the copper pot in the S4 on a stove for boiling for 10 hours, and meanwhile, continuously stirring by an electric stirrer at the stirring speed of 70r/min to obtain paste;
s6, putting the paste obtained in the step S5 into a vacuum concentration tank, and concentrating under reduced pressure to obtain a paste with the relative density of 1.25;
s7, sterilizing the paste obtained in S6, then filling the paste into a glass bottle, sealing with wax and storing, wherein the sterilization is to perform far infrared ray irradiation disinfection sterilization when the temperature is raised to 160 ℃;
s8, pouring out the paste in the step S7, adding inula flower liquid with the volume of the paste 1/50, uniformly mixing, and coating the mixture on a medicinal patch to obtain the plantar region patch with the effects of reducing blood pressure and blood fat.
Example 3
The plantar region patch with the functions of reducing blood pressure and blood fat comprises the following components in parts by mass per 100:
5g of fructus evodiae, 35g of herba ecliptae, 50g of herba portulacae, 60g of selfheal, 35g of uncaria, 20g of radix achyranthis bidentatae, 10g of rhizoma sparganii, 25g of gallnut, 10g of liquorice and 350g of corn stigma.
The invention also provides a preparation method of the arch patch with the functions of reducing blood pressure and blood fat, which comprises the following steps:
s1, weighing fructus evodiae, eclipta alba, purslane, selfheal, uncaria, achyranthes bidentata, rhizoma sparganii, gallnut, liquorice and corn stigma according to a proper mass ratio;
s2, removing impurities in fructus evodiae, eclipta alba, purslane, selfheal, uncaria, achyranthes bidentata, rhizoma sparganii, gallnut, liquorice and corn stigma weighed in the S1, wrapping the impurities with a gauze bag, soaking the wrapped gauze bag in clear water for 5 hours, then cleaning the gauze bag in an ultrasonic cleaning machine, and drying the gauze bag in a drying machine after cleaning, wherein the frequency of the ultrasonic cleaning machine is set to be 60KHz, the cleaning time is 10min, and the temperature is set to be 65 ℃;
s3, putting the dried fructus evodiae, eclipta alba, purslane, selfheal, uncaria, achyranthes bidentata, rhizoma sparganii, gallnut, liquorice and corn stigma in the S2 into a high-pressure decocting device, heating the high-pressure decocting device through steam, adding purified water, decocting the mixture for three times, respectively filtering out filtrates, and combining the filtrates;
the specific method for decocting in water comprises the following steps:
adding purified water with 4 times volume of the medicinal materials into a high-pressure decocting device for first decocting for 80min, and filtering to obtain first residue;
adding purified water with volume 3 times of that of the primary filter residue into a high-pressure decocting device for second decocting, wherein the decocting time is 60min, and filtering to obtain secondary filter residue;
adding purified water with 2 times volume of the secondary filter residue into a high-pressure decocting device for decocting for the third time, wherein the decocting time is 40min, and filtering;
s4, adding the filtrate obtained in the step S3 into a copper pot, adding the wheat glue with the volume of 1/50 into the copper pot, and stirring and mixing the mixture for 20min by using an electric stirrer, wherein the stirring speed is 200 r/min;
s5, erecting the copper pot in the step S4 on a stove for boiling for 12 hours, and meanwhile, continuously stirring by an electric stirrer at the stirring speed of 80r/min to obtain paste;
s6, putting the paste obtained in the step S5 into a vacuum concentration tank, and concentrating under reduced pressure to obtain a paste with the relative density of 1.3;
s7, sterilizing the paste obtained in S6, then filling the paste into a glass bottle, sealing with wax and storing, wherein the sterilization is to perform far infrared ray irradiation disinfection sterilization when the temperature is raised to 165 ℃;
s8, pouring out the paste in the step S7, adding inula flower liquid with the volume of the paste 1/50, uniformly mixing, and coating the mixture on a medicinal patch to obtain the plantar region patch with the effects of reducing blood pressure and blood fat.
In summary, the following steps: the plantar region patch with the functions of reducing blood pressure and blood fat provided by the invention has reasonable component proportion, is externally applied to the plantar region in a mode of a plaster patch, enters the human body through plantar acupoints, dredges the channels and collaterals, adjusts viscera, balances yin and yang, and nourishes the liver and kidney, so that the aim of reducing blood pressure and blood fat is achieved, various diseases caused by the high blood pressure and the high blood fat can be eliminated, the high blood pressure and the high blood fat can be fundamentally relieved, the blood pressure and the blood fat are stable, the blood pressure and the blood fat do not rise again after being reduced, the pain of taking the medicine for a long time is solved, the plantar region patch has the advantages of short treatment course, quick response, no toxic or side effect, no damage to other viscera, convenience in use, low price and difficulty in relapse after healing, and the aim of simultaneous treatment of principal and subordinate symptoms is achieved, the preparation method of the plantar region patch with the functions of reducing blood pressure and blood fat is simple, has the advantages of high preparation efficiency and simple production, and is easy for industrialized production.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.
Claims (8)
1. The plantar region patch with the effects of reducing blood pressure and blood fat is characterized in that the formula of the plantar region patch with the effects of reducing blood pressure and blood fat is as follows according to 100 mass components:
1-5 g of fructus evodiae, 25-35 g of eclipta alba, 30-50 g of purslane, 40-60 g of selfheal, 25-35 g of uncaria, 10-20 g of achyranthes bidentata, 5-10 g of rhizoma sparganii, 15-25 g of gallnut, 5-10 g of liquorice and 250-350 g of corn stigma.
2. The preparation method of the plantar arch patch with the effects of reducing blood pressure and blood fat as defined in claim 1, which is characterized by comprising the following steps:
s1, weighing fructus evodiae, eclipta alba, purslane, selfheal, uncaria, achyranthes bidentata, rhizoma sparganii, gallnut, liquorice and corn stigma according to a proper mass ratio;
s2, removing impurities in the fructus evodiae, the eclipta alba, the purslane, the selfheal, the uncaria, the achyranthes bidentata, the rhizoma sparganii, the gallnut, the liquorice and the corn stigma weighed in the S1, wrapping the impurities with a gauze bag, soaking the gauze bag in clear water for 3-5 hours, then putting the gauze bag into an ultrasonic cleaning machine for cleaning, and drying the gauze bag in a drying machine after cleaning;
s3, putting the dried fructus evodiae, eclipta alba, purslane, selfheal, uncaria, achyranthes bidentata, rhizoma sparganii, gallnut, liquorice and corn stigma in the S2 into a high-pressure decocting device, adding purified water, decocting for three times, filtering out filtrates respectively, and combining the filtrates for three times;
s4, adding the filtrate obtained in the step S3 into a copper pot, adding the malt extract with the volume of 1/50, and stirring and mixing for 10-20 min through an electric stirrer;
s5, erecting the copper pot in the S4 on a stove, decocting for 8-12 hours, and continuously stirring through an electric stirrer to obtain paste;
s6, putting the paste obtained in the step S5 into a vacuum concentration tank, and concentrating under reduced pressure to obtain a paste with the relative density of 1.2-1.3;
s7, sterilizing the paste obtained in the step S6, and then filling the sterilized paste into a packaging bottle for wax sealing storage;
s8, pouring out the paste in the step S7, adding inula flower liquid with the volume of the paste 1/50, uniformly mixing, and coating the mixture on a medicinal patch to obtain the plantar region patch with the effects of reducing blood pressure and blood fat.
3. The preparation method of the arch patch with the functions of reducing blood pressure and blood fat according to claim 2, which is characterized in that: the frequency of the ultrasonic cleaning machine in the S2 is set to be 40-60 KHz, the cleaning time is 5-10 min, and the temperature is set to be 55-65 ℃.
4. The preparation method of the arch patch with the functions of reducing blood pressure and blood fat according to claim 2, which is characterized in that: the specific method for decocting in water in S3 comprises the following steps:
adding purified water with the volume 4 times that of the medicinal materials into a high-pressure decocting device for first decocting, wherein the decocting time is 60-80 min, and filtering to obtain primary filter residue;
adding purified water with the volume 3 times that of the primary filter residue into a high-pressure decocting device for second decocting, wherein the decocting time is 40-60 min, and filtering to obtain secondary filter residue;
adding purified water with 2 times of volume of the secondary filter residue into a high-pressure decocting device for third decocting, wherein the decocting time is 30-40 min, and filtering.
5. The preparation method of the arch patch with the functions of reducing blood pressure and blood fat according to claim 2, which is characterized in that: the high pressure boiler in S3 is heated by steam.
6. The preparation method of the arch patch with the functions of reducing blood pressure and blood fat according to claim 2, which is characterized in that: the stirring speed of the electric stirrer in the S4 is 120-200 r/min, and the stirring speed of the electric stirrer in the S5 is 60-80 r/min.
7. The preparation method of the arch patch with the functions of reducing blood pressure and blood fat according to claim 2, which is characterized in that: and the sterilization in the S7 is to perform far infrared ray irradiation disinfection sterilization by raising the temperature to 155-165 ℃.
8. The preparation method of the arch patch with the functions of reducing blood pressure and blood fat according to claim 2, which is characterized in that: the packaging bottle in the S7 is a glass bottle.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201911025393.0A CN110694022A (en) | 2019-10-25 | 2019-10-25 | A patch for treating sole heart with blood pressure and blood lipid lowering effects, and its preparation method |
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| CN201911025393.0A CN110694022A (en) | 2019-10-25 | 2019-10-25 | A patch for treating sole heart with blood pressure and blood lipid lowering effects, and its preparation method |
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| CN1088104A (en) * | 1992-12-12 | 1994-06-22 | 赖小瑜 | Blood pressure lowing plaster and preparation method thereof |
| CN101766759A (en) * | 2008-12-30 | 2010-07-07 | 戴建国 | Medicinal footbath liquor |
| CN103239539A (en) * | 2013-05-30 | 2013-08-14 | 陈洪凯 | Compound medicine for external use for treating hypertension and application thereof |
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Application publication date: 20200117 |