CN110691787A - 针对家禽坏死性肠炎的疫苗 - Google Patents

针对家禽坏死性肠炎的疫苗 Download PDF

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Publication number
CN110691787A
CN110691787A CN201880036012.6A CN201880036012A CN110691787A CN 110691787 A CN110691787 A CN 110691787A CN 201880036012 A CN201880036012 A CN 201880036012A CN 110691787 A CN110691787 A CN 110691787A
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CN
China
Prior art keywords
polypeptide
lys
pilus
asn
seq
Prior art date
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Pending
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CN201880036012.6A
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English (en)
Chinese (zh)
Inventor
龚建华
D·莱普
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Agriculture and Agri-Food Canada
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Agriculture and Agri-Food Canada
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Application filed by Agriculture and Agri-Food Canada filed Critical Agriculture and Agri-Food Canada
Publication of CN110691787A publication Critical patent/CN110691787A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/08—Clostridium, e.g. Clostridium tetani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Gram-positive bacteria
    • C07K16/1282—Clostridium (G)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/33—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Clostridium (G)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN201880036012.6A 2017-05-31 2018-05-31 针对家禽坏死性肠炎的疫苗 Pending CN110691787A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762513001P 2017-05-31 2017-05-31
US62/513,001 2017-05-31
PCT/CA2018/050643 WO2018218360A1 (en) 2017-05-31 2018-05-31 Vaccine against necrotic enteritis in poultry

Publications (1)

Publication Number Publication Date
CN110691787A true CN110691787A (zh) 2020-01-14

Family

ID=64454163

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201880036012.6A Pending CN110691787A (zh) 2017-05-31 2018-05-31 针对家禽坏死性肠炎的疫苗

Country Status (8)

Country Link
US (2) US11318194B2 (https=)
EP (1) EP3630800A4 (https=)
JP (2) JP2020527051A (https=)
CN (1) CN110691787A (https=)
BR (1) BR112019025019A2 (https=)
CA (1) CA3064461A1 (https=)
MX (1) MX2019014450A (https=)
WO (1) WO2018218360A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113234130A (zh) * 2021-05-24 2021-08-10 安徽医科大学第四附属医院 一种卡氏肺孢子菌重组蛋白及其制备方法与应用

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025199604A1 (en) * 2024-03-27 2025-10-02 Université de Montréal Recombinant vaccine proteins for the prevention of avian necrotic enteritis

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101198352A (zh) * 2005-04-18 2008-06-11 谢尔英·普劳有限公司 产气荚膜梭菌α类毒素疫苗
WO2008146164A2 (en) * 2007-05-25 2008-12-04 Novartis Ag Streptococcus pneumoniae pilus antigens
CN101578109A (zh) * 2006-10-27 2009-11-11 陶氏益农公司 用于坏死性肠炎的、包含突变的产气荚膜梭菌α毒素抗原的家禽疫苗及生产疫苗的方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1958962A3 (en) * 1997-06-12 2013-05-01 Novartis International Pharmaceutical Ltd. Artificial antibody polypeptides
AU6094000A (en) * 1999-07-13 2001-01-30 Med Immune, Inc. Donor strand complemented pilin and adhesin broad-based vaccines
WO2007116322A2 (en) * 2006-02-17 2007-10-18 Novartis Ag Purification of bacterial antigens
US20100062025A1 (en) * 2006-11-20 2010-03-11 Intervet International B.V. Use of Clostridium perfringens type C bacterium for the manufacture of a vaccine
PL2164862T3 (pl) * 2007-06-08 2015-12-31 Australian Poultry Crc Pty Ltd Toksyna netb z clostridium
EP2162150A4 (en) * 2007-06-22 2011-10-12 Univ Guelph VACCINE AGAINST CLOSTRIDIUM PERFRINGENS
WO2011113801A1 (en) * 2010-03-16 2011-09-22 Universiteit Gent Use of clostridium perfringens strain 23 to protect against necrotic enteritis
AR099470A1 (es) * 2014-02-17 2016-07-27 Intervet Int Bv Vacunas de virus de aves de corral líquidas
FR3065623B1 (fr) * 2017-04-28 2021-07-09 Roquette Freres Albumines de pois ameliorees, procede d'obtention et leurs applications
MX2021000184A (es) * 2018-07-05 2021-05-12 Novobind Livestock Therapeutics Inc Anticuerpos contra agentes patogenos en aves de corral y sus aplicaciones.

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101198352A (zh) * 2005-04-18 2008-06-11 谢尔英·普劳有限公司 产气荚膜梭菌α类毒素疫苗
CN101578109A (zh) * 2006-10-27 2009-11-11 陶氏益农公司 用于坏死性肠炎的、包含突变的产气荚膜梭菌α毒素抗原的家禽疫苗及生产疫苗的方法
WO2008146164A2 (en) * 2007-05-25 2008-12-04 Novartis Ag Streptococcus pneumoniae pilus antigens

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
GENBANK: "hypothetical protein BXT94_03025 [Clostridium perfringens]" *
GENBANK: "hypothetical protein BXT94_03035 [Clostridium perfringens]" *
GENBANK: "putative collagen adhesin [Clostridium perfringens]" *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113234130A (zh) * 2021-05-24 2021-08-10 安徽医科大学第四附属医院 一种卡氏肺孢子菌重组蛋白及其制备方法与应用

Also Published As

Publication number Publication date
JP2023090702A (ja) 2023-06-29
RU2019137515A3 (https=) 2021-12-03
EP3630800A1 (en) 2020-04-08
CA3064461A1 (en) 2018-12-06
US11318194B2 (en) 2022-05-03
BR112019025019A2 (pt) 2020-06-30
US20200093913A1 (en) 2020-03-26
MX2019014450A (es) 2020-02-10
EP3630800A4 (en) 2021-03-24
WO2018218360A1 (en) 2018-12-06
US20220226455A1 (en) 2022-07-21
JP2020527051A (ja) 2020-09-03
RU2019137515A (ru) 2021-06-30

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