CN110651864A - Functional beverage for promoting wound healing and preparation method and application thereof - Google Patents
Functional beverage for promoting wound healing and preparation method and application thereof Download PDFInfo
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23F—COFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF
- A23F3/00—Tea; Tea substitutes; Preparations thereof
- A23F3/16—Tea extraction; Tea extracts; Treating tea extract; Making instant tea
- A23F3/163—Liquid or semi-liquid tea extract preparations, e.g. gels, liquid extracts in solid capsules
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/82—Theaceae (Tea family), e.g. camellia
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A61P17/10—Anti-acne agents
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/169—Plantarum
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Abstract
The invention provides a functional beverage for promoting wound healing and a preparation method and application thereof, wherein the functional beverage comprises the following raw materials in parts by mass: 5-10 parts of moringa leaves, 3-10 parts of poria cocos tea, 0.5-2 parts of ledebouriella leaves, 3-6 parts of storax, 1-5 parts of liquorice, 5-15 parts of radix sophorae flavescentis, 5-10 parts of chrysanthemum, 3-8 parts of blueberries and 20-40 parts of distilled water. The invention solves the severe requirements on diet in the traditional wound healing or acne healing or drug treatment process. The beverage provided by the invention has the advantages of full mouthfeel and pure flavor, and has the functions of promoting metabolism of a human body and enhancing immunity of the human body while relieving pain of wounds and accelerating wound healing.
Description
Technical Field
The invention belongs to the technical field of food engineering, and particularly relates to a functional beverage for promoting wound healing and a preparation method and application thereof.
Background
Acne is a chronic inflammatory skin disease of a pilosebaceous unit, the occurrence of acne is mainly closely related to factors such as excessive sebum secretion, blockage of pilosebaceous ducts, bacterial infection, inflammatory reaction and the like, the acne is mainly caused by polymorphic skin lesions such as facial acnes, papules, pustules, nodules and the like, the acne rash per se or the left scars can influence the beauty of the face and the daily life, and the requirements of acne patients on diet are harsh generally.
Wound healing refers to the healing process after the body is subjected to external force and the skin and other tissues are separated or damaged, and comprises the complex combination of regeneration of various tissues, granulation tissue proliferation and scar tissue formation, and the synergistic effect of various processes is shown. The extent of the injury and the regenerative capacity of the tissue determine the manner of repair, the time of healing and the size of the scar. Some adverse factors should be avoided during wound healing to create favorable conditions to promote tissue regenerative repair. Therefore, there is also a need for diet.
At present, the traditional wound healing or acne mainly heals naturally or is treated by medicaments according to the severity of wounds, the requirement on diet is to avoid pungent and pungent food stimulation as much as possible, however, the dependence or side effect of the medicaments is extremely large, and recessive injury is brought to the body. Therefore, a functional drink which can be regulated from diet and promote wound healing has certain market demand.
Disclosure of Invention
The invention aims to provide a functional beverage for promoting wound healing, which can be combined with the traditional Chinese medicine conditioning theory from the aspect of nutrition, has the characteristics of antibiosis, antiphlogosis, rich nutrition and the like, can fundamentally condition the metabolism of a body, and promotes wound or acne healing.
Meanwhile, the invention provides a preparation method of the functional beverage for promoting wound healing, which has the advantages of simple process, full dissolution of active ingredients and less loss of nutritional ingredients.
The functional beverage for promoting wound healing is applied to the aspects of supplementary food for repairing scars and acnes or nutritional meal matched drinks as an auxiliary food therapy product.
In order to achieve the purpose, the invention adopts the technical scheme that:
a functional beverage for promoting wound healing comprises the following raw materials in parts by mass:
5-10 parts of moringa leaves, 3-10 parts of poria cocos tea, 0.5-2 parts of ledebouriella leaves, 3-6 parts of storax, 1-5 parts of liquorice, 5-15 parts of radix sophorae flavescentis, 5-10 parts of chrysanthemum, 3-8 parts of blueberries and 20-40 parts of distilled water.
Further preferably, the feed comprises the following raw materials in parts by mass:
6-8 parts of moringa leaves, 5-8 parts of poria cocos tea, 1-2 parts of ledebouriella leaves, 4-5 parts of storax, 2-3 parts of liquorice, 6-8 parts of radix sophorae flavescentis, 5-6 parts of chrysanthemum, 3-5 parts of blueberries and 20-40 parts of distilled water.
The preparation method of the functional beverage for promoting wound healing comprises the following steps:
1) weighing liquorice pieces, adding 5 times of water, decocting for 40-60 min, adding 2 times of water into material residues, repeatedly decocting to obtain decoction, recovering, and mixing to obtain liquorice juice for later use;
2) weighing Moringa oleifera leaf, Poria tea, folium Saposhnikoviae, storax, and radix Sophorae Flavescentis at a certain proportion, and soaking with Glycyrrhrizae radix juice for 20-30 min;
3) adding 10-20 times of pure water into the mixture obtained in the step (2), adding chrysanthemum, decocting for 40-80min, and filtering;
4) adding 3-5 times of pure water into the material residue obtained in the step 3), decocting for 60-90min, filtering, and combining the two filtrates;
5) squeezing juice from fully ripe wild fructus Myrtilli, adding Lactobacillus plantarum, and fermenting at 26-35 deg.C for 3-5 hr to obtain fructus Myrtilli fermentation liquid;
6) mixing the blueberry fermentation liquor with the combined filtrate obtained in the step 4), and performing ultrasonic sterilization at 50-200W for 15-30min to obtain the functional beverage for promoting wound healing.
Further limiting, the inoculation amount of the lactobacillus plantarum is 3-5% of the mass of the blueberry juice.
Further defined, the fermentation conditions in the step (5) are: fermenting at 30-35 deg.C for 4 hr.
Further preferably, the mass ratio of the moringa leaves to the Fu tea is 1: 1.
the functional beverage for promoting wound healing is applied to the aspects of supplementary food for repairing scars and acnes or a nutritional meal matched beverage as an auxiliary dietary therapy product.
The moringa oleifera leaves are rich in various mineral substances, vitamins, 20 amino acids, 46 antioxidants and various mineral substances, have the effects of reducing blood sugar, blood fat and blood pressure, resisting tumors and oxidation, relaxing bowels, promoting urination, expelling parasites, improving sleep and the like, and can enhance the immune function of a human body, delay senility and prevent diseases after being eaten for a long time.
The Fuzhuan tea contains substances such as vitamins, minerals, proteins, amino acids, tea polysaccharide and the like, caffeine, vitamins, amino acids and other components which are beneficial to human digestion and can regulate metabolism, and also contains the amino acids and theanine which can play the roles of inhibiting blood pressure rise, resisting blood failure, promoting fibrinolysis, preventing platelet adhesion and aggregation and inhibiting arterial smooth muscle cell proliferation by activating dopamine enzyme neurons.
Ledebouriella root, radix Ledebouriellae, has the effects of relieving exterior syndrome, expelling wind, eliminating dampness and relieving spasm.
Storax has effects of inducing resuscitation and removing filth, resolving stagnation and eliminating phlegm, activating qi-flowing and relieving pain.
The kuh-seng can promote the growth and repair of damaged vascular nerve cells, and has good effects of relieving postoperative pain and accelerating wound healing.
The functional beverage for promoting wound healing has the advantages that the traditional Chinese medicine components such as the ledebouriella seseloides leaves, the storax and the radix sophorae flavescentis are fused with the nutrient components such as the fu tea, the moringa leaves and the blueberries which are rich in vitamins and phenolic substances, the metabolism of a human body is promoted, the immune function of the human body is enhanced, the nutrient absorption is promoted, the wound pain is relieved, and the wound healing is accelerated.
Detailed Description
The technical solution of the present invention will be further described with reference to examples and experiments, but the present invention is not limited to the following embodiments.
Example 1
A functional beverage for promoting wound healing comprises the following raw materials in parts by mass:
7 parts of moringa leaves, 7 parts of poria cocos tea, 2 parts of ledebouriella leaves, 5 parts of storax, 3 parts of liquorice, 6 parts of radix sophorae flavescentis, 5 parts of chrysanthemum, 4 parts of blueberries and 30 parts of distilled water.
The functional beverage for promoting wound healing is prepared by the following steps:
1) weighing and adding 5 times of water into liquorice decoction pieces, decocting for 50min, adding 2 times of water into material residues, repeatedly decocting to obtain decoction, recovering, and mixing to obtain liquorice juice for later use;
2) weighing Moringa oleifera leaf, Poria tea, folium Saposhnikoviae, storax, and radix Sophorae Flavescentis at a certain proportion, and soaking with Glycyrrhrizae radix juice for 30 min;
3) adding 15 times of pure water into the mixture obtained in the step (2), adding chrysanthemum, decocting for 60min, and filtering;
4) adding 8 times of pure water into the material residue in the step 3), decocting for 70min, filtering, and combining the two filtrates;
5) juicing fully-ripe wild blueberry, adding lactobacillus plantarum, placing in a fermentation tank, and fermenting at 32 deg.C for 4h to obtain blueberry fermentation liquid, wherein the inoculation amount of lactobacillus plantarum is 4% of the weight of blueberry juice;
6) mixing the blueberry fermentation liquor with the combined filtrate obtained in the step 4), and performing ultrasonic sterilization at 100W for 20min to obtain the functional beverage for promoting wound healing.
Example 2
A functional beverage for promoting wound healing comprises the following raw materials in parts by mass:
6 parts of moringa leaves, 5 parts of poria cocos tea, 1 part of ledebouriella leaves, 4 parts of storax, 2 parts of liquorice, 8 parts of radix sophorae flavescentis, 6 parts of chrysanthemum, 3 parts of blueberries and 25 parts of distilled water.
The functional beverage for promoting wound healing is prepared by the following steps:
1) weighing and adding 5 times of water into liquorice decoction pieces, decocting for 40min, adding 3 times of water into material residues, repeatedly decocting to obtain decoction, recovering, and mixing to obtain liquorice juice for later use;
2) weighing Moringa oleifera leaf, Poria tea, folium Saposhnikoviae, storax, and radix Sophorae Flavescentis at a certain proportion, and soaking with Glycyrrhrizae radix juice for 20 min;
3) adding 10 times of pure water into the mixture obtained in the step (2), adding chrysanthemum, decocting for 80min, and filtering;
4) adding 7 times of pure water into the material residue in the step 3), decocting for 60min, filtering, and combining the two filtrates;
5) juicing fully-ripe wild blueberry, adding lactobacillus plantarum, placing in a fermentation tank, and fermenting at 35 deg.C for 3h to obtain blueberry fermentation liquid, wherein the inoculation amount of lactobacillus plantarum is 3% of the weight of blueberry juice;
6) mixing the blueberry fermentation liquor with the combined filtrate obtained in the step 4), and performing ultrasonic sterilization at 50W for 30min to obtain the functional beverage for promoting wound healing.
Example 3
A functional beverage for promoting wound healing comprises the following raw materials in parts by mass:
8 parts of moringa leaves, 8 parts of poria cocos tea, 1 part of ledebouriella leaves, 4 parts of storax, 2 parts of liquorice, 6 parts of radix sophorae flavescentis, 5 parts of chrysanthemum, 5 parts of blueberries and 20 parts of distilled water.
The functional beverage for promoting wound healing is prepared by the following steps:
1) weighing liquorice pieces, adding 5 times of water, decocting for 60min, adding 3 times of water into the material residues, repeatedly decocting to obtain decoction, recovering, and mixing to obtain liquorice juice for later use;
2) weighing Moringa oleifera leaf, Poria tea, folium Saposhnikoviae, storax, and radix Sophorae Flavescentis at a certain proportion, and soaking with Glycyrrhrizae radix juice for 30 min;
3) adding 8 times of pure water into the mixture obtained in the step (2), adding chrysanthemum, decocting for 40min, and filtering;
4) adding 4 times of pure water into the material residue obtained in the step 3), decocting for 90min, filtering, and combining the two filtrates;
5) juicing fully-ripe wild blueberry, adding lactobacillus plantarum, placing in a fermentation tank, and fermenting at 26 deg.C for 5h to obtain blueberry fermentation liquid, wherein the inoculation amount of lactobacillus plantarum is 5% of the weight of blueberry juice;
6) mixing the blueberry fermentation liquor with the combined filtrate obtained in the step 4), and performing ultrasonic sterilization at 200W for 15min to obtain the functional beverage for promoting wound healing.
Example 4
A functional beverage for promoting wound healing comprises the following raw materials in parts by mass:
5 parts of moringa leaves, 3 parts of poria cocos tea, 2 parts of ledebouriella leaves, 6 parts of storax, 1 part of liquorice, 15 parts of radix sophorae flavescentis, 10 parts of chrysanthemum, 8 parts of blueberries and 40 parts of distilled water.
The functional beverage for promoting wound healing is prepared by the following steps:
1) weighing liquorice pieces, adding 10 times of water, decocting for 50min, adding 5 times of water into the material residues, repeatedly decocting to obtain decoction, recovering, and mixing to obtain liquorice juice for later use;
2) weighing Moringa oleifera leaf, Poria tea, folium Saposhnikoviae, storax, and radix Sophorae Flavescentis at a certain proportion, and soaking with Glycyrrhrizae radix juice for 30 min;
3) adding 15 times of pure water into the mixture obtained in the step (2), adding chrysanthemum, decocting for 60min, and filtering;
4) adding 10 times of pure water into the material residue in the step 3), decocting for 70min, filtering, and combining the two filtrates;
5) juicing fully-ripe wild blueberry, adding lactobacillus plantarum, placing in a fermentation tank, and fermenting at 32 deg.C for 4h to obtain blueberry fermentation liquid, wherein the inoculation amount of lactobacillus plantarum is 4% of the weight of blueberry juice;
6) mixing the blueberry fermentation liquor with the combined filtrate obtained in the step 4), and performing ultrasonic sterilization at 150W for 20min to obtain the functional beverage for promoting wound healing.
Example 5
A functional beverage for promoting wound healing comprises the following raw materials in parts by mass:
10 parts of moringa leaves, 10 parts of poria cocos tea, 0.5 part of ledebouriella leaves, 3 parts of storax, 5 parts of liquorice, 5 parts of radix sophorae flavescentis, 5 parts of chrysanthemum, 3 parts of blueberries and 20 parts of distilled water.
Example 6
10 parts of moringa leaves, 5 parts of poria cocos tea, 1 part of ledebouriella leaves, 4 parts of storax, 2 parts of liquorice, 10 parts of radix sophorae flavescentis, 8 parts of chrysanthemum, 5 parts of blueberries and 30 parts of distilled water.
The functional beverage for promoting wound healing can be used as an auxiliary food therapy product, can promote the repair of scars and acnes, and can be used as a supplementary food or a nutritional meal matched beverage.
First, sensory evaluation
Color: brown colour
Fragrance: has light Fu tea flavor and Chinese medicinal flavor
Appearance: the liquid is uniform and has no foreign matter or precipitate
Second, wound healing Effect
100 patients with mild and moderate skin injuries are selected, wherein 30 patients drink the functional beverage for promoting wound healing of the embodiment 1 of the invention after half an hour of meal every day, and 20 patients drink the functional beverage for promoting wound healing of the embodiment 2 of the invention after half an hour of meal every day and continuously drink the functional beverages; on the other hand, 50 of the same meals as the first 50 of the meals without drinking the product of the present invention were counted for the wound healing time and the scar rate, and the results are shown in table 1.
Table 1 shows the efficacy and mouthfeel of the beverage products obtained in the examples
As can be seen from the above table 1, the wound healing time of the invention examples 1 and 2 can be improved by about 4-7 days, the scar rate can be reduced by about 11%, the wound healing can be promoted by continuously drinking the beverage of the invention, and the beverage has unique flavor and slightly sour taste, can promote appetite, and helps the intestinal digestion and absorption.
Claims (7)
1. A functional beverage for promoting wound healing is characterized by comprising the following raw materials in parts by mass:
5-10 parts of moringa leaves, 3-10 parts of poria cocos tea, 0.5-2 parts of ledebouriella leaves, 3-6 parts of storax, 1-5 parts of liquorice, 5-15 parts of radix sophorae flavescentis, 5-10 parts of chrysanthemum, 3-8 parts of blueberries and 20-40 parts of distilled water.
2. The functional beverage for promoting wound healing according to claim 1, which is characterized by comprising the following raw materials in parts by mass:
6-8 parts of moringa leaves, 5-8 parts of poria cocos tea, 1-2 parts of ledebouriella leaves, 4-5 parts of storax, 2-3 parts of liquorice, 6-8 parts of radix sophorae flavescentis, 5-6 parts of chrysanthemum, 3-5 parts of blueberries and 20-40 parts of distilled water.
3. The method for preparing a functional beverage for promoting wound healing according to claim 1, comprising the steps of:
1) weighing liquorice pieces, adding 5 times of water, decocting for 40-60 min, adding 2 times of water into material residues, repeatedly decocting to obtain decoction, recovering, and mixing to obtain liquorice juice for later use;
2) weighing Moringa oleifera leaf, Poria tea, folium Saposhnikoviae, storax, and radix Sophorae Flavescentis at a certain proportion, and soaking with Glycyrrhrizae radix juice for 20-30 min;
3) adding 10-20 times of pure water into the mixture obtained in the step (2), adding chrysanthemum, decocting for 40-80min, and filtering;
4) adding 3-5 times of pure water into the material residue obtained in the step 3), decocting for 60-90min, filtering, and combining the two filtrates;
5) squeezing juice from fully ripe wild fructus Myrtilli, adding Lactobacillus plantarum, and fermenting at 26-35 deg.C for 3-5 hr to obtain fructus Myrtilli fermentation liquid;
6) mixing the blueberry fermentation liquor with the combined filtrate obtained in the step 4), and performing ultrasonic sterilization at 50-200W for 15-30min to obtain the functional beverage for promoting wound healing.
4. The preparation method of the functional beverage for promoting wound healing according to claim 3, wherein the inoculation amount of the lactobacillus plantarum is 3-5% of the mass of the blueberry juice.
5. The method for preparing a functional beverage for promoting wound healing according to claim 3, wherein the fermentation conditions in the step (5) are: fermenting at 30-35 deg.C for 4 hr.
6. The preparation method of the functional beverage for promoting wound healing according to claim 3, wherein the mass ratio of the moringa leaves to the fu tea is 1: 1.
7. use of the functional beverage for promoting wound healing according to claim 1 as a supplementary food or a nutritional meal drink for repairing scars and acne as a supplementary dietary product.
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