CN110623129A - Pressed candy rich in fucoidin and application thereof - Google Patents
Pressed candy rich in fucoidin and application thereof Download PDFInfo
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- CN110623129A CN110623129A CN201911027798.8A CN201911027798A CN110623129A CN 110623129 A CN110623129 A CN 110623129A CN 201911027798 A CN201911027798 A CN 201911027798A CN 110623129 A CN110623129 A CN 110623129A
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- stomach
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- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims abstract description 8
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- SUVMJBTUFCVSAD-UHFFFAOYSA-N sulforaphane Chemical compound CS(=O)CCCCN=C=S SUVMJBTUFCVSAD-UHFFFAOYSA-N 0.000 description 4
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- 241000195493 Cryptophyta Species 0.000 description 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/42—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds characterised by the carbohydrates used, e.g. polysaccharides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/48—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing plants or parts thereof, e.g. fruits, seeds, extracts
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/50—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by shape, structure or physical form, e.g. products with supported structure
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention discloses a pressed candy rich in fucoidin and application thereof, relating to the technical field of food. The composite material comprises the following raw materials in parts by weight: 0.1-30 parts of fucoidin, 0.1-5 parts of chitosan oligosaccharide, 5-10 parts of sodium alginate, 30-60 parts of herbal stomach nourishing powder, 5-30 parts of sorbitol, 1-10 parts of microcrystalline cellulose and 0.5-1 part of magnesium stearate. The herbal stomach nourishing powder is any one or a combination of more of champignon powder, ginger powder, tuckahoe powder, tangerine peel powder, broccoli powder, hawthorn powder and Chinese date powder, and the specification of the obtained tablet candy is 0.2 g/tablet to 2.0 g/tablet. The invention takes fucoidin, chitosan oligosaccharide, sodium alginate and herbal stomach nourishing powder as main raw materials, which are all homologous medicine and food or common food raw materials, is leisure food which can effectively eliminate helicobacter pylori in oral cavity and stomach and can strengthen spleen and nourish stomach, and can avoid the side effect of conventional medicament treatment antibiotics on human bodies.
Description
Technical Field
The invention relates to the technical field of foods, in particular to a delicate stomach-nourishing type tablet candy rich in fucoidin.
Background
A large number of clinical cases and research results show that helicobacter pylori infection is an important reason for the occurrence and recurrence of stomach diseases; WHO has listed helicobacter pylori as a class 1 carcinogen for gastric cancer. At present, the common medicament for helicobacter pylori infection is antibiotic, and the side effect is not negligible.
Fucoidin is mainly distributed in the surface mucus of brown algae, and belongs to natural active polysaccharide. A large number of researches find that the specific active group of the fucoidin can be biologically compatible with helicobacter pylori, remove the helicobacter pylori in the digestive tract and protect the gastric mucosa from being invaded by the helicobacter pylori; the fucoidin with proper concentration can obviously inhibit the growth and proliferation of helicobacter pylori. In addition, the fucoidin has the effects of bidirectionally regulating intestinal tracts, improving constipation and enteritis and enhancing immunity.
The chitosan oligosaccharide is the only cationic basic amino oligosaccharide with positive charge in nature, has better antibacterial activity, and can inhibit the growth and reproduction of bacteria, fungi and viruses. Chitosan oligosaccharide, natural macromolecule biological functionality, biocompatibility, blood compatibility, safety, microbial degradability and other excellent performances are widely applied to food, medicine, chemical industry and other industries.
Sodium alginate is soluble natural polysaccharide extracted from brown algae such as herba Zosterae Marinae and Macrocystis. Researches find that sodium alginate reacts with gastric acid in the stomach to form alginic acid, and the alginic acid floats on the surface of the gastric juice like a quilt and plays a role in preventing the acid from regurgitating.
The herbal stomach nourishing powder integrates the seven food raw materials of the champignon powder, the ginger powder, the tuckahoe powder, the tangerine peel powder, the broccoli powder, the hawthorn powder and the Chinese date powder for strengthening the spleen and nourishing the stomach, and is safe and reliable. Traditional Chinese medicine and modern medicine think that: hericium erinaceus has effects of benefiting five internal organs, promoting digestion, invigorating stomach, tonifying deficiency, resisting cancer, and replenishing kidney essence; ginger, rhizoma Zingiberis recens, warming middle energizer to dispel cold, restoring yang and dredging collaterals; tuckahoe, Poria promotes diuresis and eliminates dampness, invigorates the spleen; the dried orange peel has the effects of regulating qi, strengthening spleen, eliminating dampness and reducing phlegm; broccoli, which is rich in sulforaphane and is beneficial to resisting helicobacter pylori; the hawthorn can stimulate the appetite and help digestion; the Chinese date has the effects of tonifying spleen and stomach, benefiting qi and promoting the production of body fluid. Hawthorn and jujube also impart a pleasant flavor mouthfeel to the tabletted confections.
It is well known that helicobacter pylori is susceptible to infection and is distributed in the mouth, stomach and entire digestive tract of humans. A large amount of helicobacter pylori exists in the oral cavity of a patient infected with helicobacter pylori, other people can be infected by saliva, and a family eating together is a potential high-risk infected group. The disease enters from the mouth and blocks the breeding and transmission of the helicobacter pylori from the root, and is the key to treat the helicobacter pylori infection and protect the family from the helicobacter pylori infection.
According to research, no related research report on the helicobacter pylori-eliminating spleen-invigorating and stomach-nourishing type tablet candy exists at present, and no related product is on the market. When gastrointestinal diseases are high, the demands for delicate stomach nourishing are rising more and more; the tablet candy is a brand new expression form of functional food because of its sweet and sour taste and convenient carrying. Therefore, the delicate stomach-nourishing pressed candy which is helpful for clearing helicobacter pylori in oral cavity and stomach is developed, consumers can realize the delicate stomach nourishing through the portable and delicious leisure candy, the health of the family is cared, and the candy has wide market prospect.
Disclosure of Invention
The invention aims to provide a pressed candy rich in fucoidin and application thereof, which can eliminate helicobacter pylori in oral cavity and stomach, strengthen spleen and nourish stomach, and avoid side effects on human body caused by conventional drug antibiotic treatment.
One of the tasks of the invention is to provide a pressed candy rich in fucoidin, and the technical proposal comprises the following steps:
the pressed candy rich in fucoidin is characterized by comprising the following raw materials in parts by weight:
0.1-30 parts of fucoidin, 5-10 parts of sodium alginate, 30-60 parts of herbal stomach nourishing powder, 5-30 parts of sorbitol, 1-10 parts of microcrystalline cellulose and 0.5-1 part of magnesium stearate.
As a preferable scheme of the invention, the raw materials also comprise 0.1-5 parts of chitosan oligosaccharide by weight.
In another preferred embodiment of the present invention, the fucoidan is in the form of powder or liquid, and the purity of the fucoidan in the form of powder or liquid is 5 to 95%.
Further, the viscosity of 10% by mass of sodium alginate is 200-700 cps.
Further, the herbal stomach nourishing powder is any one or a combination of more of champignon powder, ginger powder, tuckahoe powder, tangerine peel powder, broccoli powder, hawthorn powder and Chinese date powder.
Furthermore, the specification of the tabletted candy is 0.2 g/tablet to 2.0 g/tablet.
Another task of the invention is to provide the application of the tabletting candy rich in fucoidin in clearing helicobacter pylori in oral cavity and stomach.
Compared with the prior art, the invention has the following beneficial technical effects:
(1) the fucoidin added in the raw materials of the invention is mainly distributed in the surface mucus of brown algae, belonging to natural active polysaccharide. The specific active group of the fucoidin can be biologically compatible with helicobacter pylori, so that the helicobacter pylori in the oral cavity and the digestive tract can be eliminated, and the gastric mucosa can be protected from being invaded by the helicobacter pylori; the fucoidin with proper concentration can obviously inhibit the growth and proliferation of helicobacter pylori. In addition, the fucoidin has the effect of conditioning the intestinal tract bidirectionally, improving constipation and enteritis and playing a role in maintaining the intestinal tract.
(2) The chitosan oligosaccharide added in the raw materials of the invention is the only cationic basic amino oligosaccharide with positive charge in nature, has better antibacterial activity and can inhibit the growth and the propagation of bacteria, fungi and viruses. Chitosan oligosaccharide, natural macromolecule biological functionality, biocompatibility, blood compatibility, safety, microbial degradability and other excellent performances are widely applied to food, medicine, chemical industry and other industries.
(3) The sodium alginate added in the raw materials of the invention is soluble natural polysaccharide extracted from brown algae such as kelp and kelp. Researches find that sodium alginate reacts with gastric acid in the stomach to form alginic acid, and the alginic acid floats on the surface of the gastric juice like a quilt and plays a role in preventing the acid from regurgitating.
(4) The herbal stomach nourishing powder added in the raw materials integrates the raw materials of the champignon powder, the ginger powder, the tuckahoe powder, the tangerine peel powder, the broccoli powder, the hawthorn powder and the Chinese date powder, and is safe and reliable, and the traditional Chinese medicine and modern medicine think that: hericium erinaceus has effects of benefiting five internal organs, promoting digestion, invigorating stomach, tonifying deficiency, resisting cancer, and replenishing kidney essence; ginger, rhizoma Zingiberis recens, warming middle energizer to dispel cold, restoring yang and dredging collaterals; tuckahoe, Poria promotes diuresis and eliminates dampness, invigorates the spleen; the dried orange peel has the effects of regulating qi, strengthening spleen, eliminating dampness and reducing phlegm; broccoli, which is rich in sulforaphane and is beneficial to resisting helicobacter pylori; the hawthorn can stimulate the appetite and help digestion; the Chinese date has the effects of tonifying spleen and stomach, benefiting qi and promoting the production of body fluid. Hawthorn and jujube also impart a pleasant flavor mouthfeel to the tabletted confections.
(5) The invention takes fucoidin, chitosan oligosaccharide, sodium alginate and herbal stomach nourishing powder (comprising champignon powder, ginger powder, tuckahoe powder, tangerine peel powder, broccoli powder, hawthorn powder and Chinese date powder) as main raw materials, and the raw materials are all edible and common food raw materials, so that the leisure food is extremely effective in clearing helicobacter pylori in oral cavity and stomach, tonifying spleen and nourishing stomach, can avoid side effects of conventional pharmacotherapy antibiotics on human bodies, and has extremely wide application prospect.
Detailed Description
The invention provides a pressed candy rich in fucoidin and application thereof, and in order to make the advantages and technical scheme of the invention clearer and clearer, the invention is explained in detail by combining specific embodiments.
The main raw materials of the invention are fucoidin, sorbitol and sodium alginate, and are produced by Qingdao Mingyue algae biological health science and technology group, Inc.
Example 1:
a faint stomach-nourishing type tablet candy rich in fucoidin is composed of the following substances: 30 parts of fucoidin, 2 parts of chitosan oligosaccharide, 10 parts of sodium alginate, 50.5 parts of herbal stomach nourishing powder, 5 parts of sorbitol, 2 parts of microcrystalline cellulose and 0.5 part of magnesium stearate; the herbal stomach nourishing powder consists of monkey mushroom powder, ginger powder, poria cocos powder, tangerine peel powder, broccoli powder, hawthorn powder and Chinese date powder in a weight ratio of 5:5:1:0:2:6: 1.
Efficacy experimental data:
case (2): a woman, 54 years old. The change in HP antibody-UBT values is shown in Table 1:
TABLE 1 change in HP antibody-UBT values
And (3) taking experience display: after eating the product for 10 days, the stomachache and the burning sensation are relieved, and the product does not rise at night; after eating the product for 20 days, the burning sensation of the stomach disappears; after eating the product for 30 days, the stomach discomfort disappears, and the appetite is greatly increased; after 50 days of eating the product, the detection of helicobacter pylori is changed from positive to negative, and the weight of the product is increased by 2 kilograms from 50 days of eating the product.
Example 2:
a faint stomach-nourishing type tablet candy rich in fucoidin is composed of the following substances: 0.1 part of fucoidin, 2.9 parts of chitosan oligosaccharide, 5 parts of sodium alginate, 60 parts of herbal stomach nourishing powder, 21 parts of sorbitol, 10 parts of microcrystalline cellulose and 1 part of magnesium stearate; the herbal stomach nourishing powder is prepared from monkey mushroom powder, ginger powder, poria cocos powder, tangerine peel powder, broccoli powder, hawthorn powder and Chinese date powder in a weight ratio of 3: 2:0:4:2:1: 3.
Case (2): a woman, 36 years old. The urea [14C ] -UBT measurements vary as shown in Table 2:
TABLE 2 variation of urea [14C ] -UBT measurement values
And (3) taking experience display: after eating the product for 30 days, stomach discomfort disappears, and appetite is increased; after eating the product for 49 days, the helicobacter pylori detection is changed from positive to negative.
Example 3:
a faint stomach-nourishing type tablet candy rich in fucoidin is composed of the following substances: 18.4 parts of fucoidin, 4 parts of chitosan oligosaccharide, 9 parts of sodium alginate, 30 parts of herbal stomach nourishing powder, 30 parts of sorbitol, 8 parts of microcrystalline cellulose and 0.6 part of magnesium stearate; the herbal stomach nourishing powder consists of monkey mushroom powder, ginger powder, poria cocos powder, tangerine peel powder, broccoli powder, hawthorn powder and Chinese date powder in a weight ratio of 2:1:0:2:0:5: 2.
Efficacy experimental data:
case (2): a male, age 27. The urea [14C ] -UBT measurements vary as shown in Table 3:
TABLE 3 variation of urea [14C ] -UBT measurement values
And (3) taking experience display: after eating the product for 15 days, the stomach pain and burning sensation are obviously weakened; after eating the product for 30 days, stomachache disappears and appetite begins to increase; after eating the product for 60 days, stomachache and burning sensation disappear; the 94 th day of eating the product, the helicobacter pylori index urea [14C ]]The detection value is determined from the original 1340dmp/mmol CO2Reduced to 164dmp/mmol CO2。
Example 4:
a faint stomach-nourishing type tablet candy rich in fucoidin is composed of the following substances: 9.1 parts of fucoidin, 3 parts of chitosan oligosaccharide, 2 parts of sodium alginate, 55 parts of herbal stomach nourishing powder, 25 parts of sorbitol, 5 parts of microcrystalline cellulose and 0.9 part of magnesium stearate; the herbal stomach nourishing powder is ginger powder.
Efficacy experimental data:
case (2): a woman, 53 years old. The urea [14C ] -UBT measurements vary as shown in Table 4:
TABLE 4 variation of urea [14C ] -UBT measurement values
And (3) taking experience display: after eating the product for 30 days, the helicobacter pylori is converted from positive to negative.
Other combinations not exemplified are obvious implementations under the guidance of the above examples 1-4.
The parts which are not described in the invention can be realized by taking the prior art as reference.
It should be noted that: any equivalents or obvious modifications thereof which may occur to persons skilled in the art and which are given the benefit of this description are deemed to be within the scope of the invention.
Claims (7)
1. The pressed candy rich in fucoidin is characterized by comprising the following raw materials in parts by weight:
0.1-30 parts of fucoidin, 5-10 parts of sodium alginate, 30-60 parts of herbal stomach nourishing powder, 5-30 parts of sorbitol, 1-10 parts of microcrystalline cellulose and 0.5-1 part of magnesium stearate.
2. The fucoidan-enriched tabletted candy according to claim 1, wherein the ratio of: also comprises 0.1-5 parts of chitosan oligosaccharide.
3. The fucoidan-enriched tabletted candy according to claim 1, wherein the ratio of: the fucoidin is in powder or liquid state, and the purity of the fucoidin in powder or liquid state is 5-95%.
4. The fucoidan-enriched tabletted candy according to claim 1, wherein the ratio of: the viscosity of 10% by mass of sodium alginate is 200-700 cps.
5. The fucoidan-enriched tabletted candy according to claim 1, wherein the ratio of: the herbal stomach nourishing powder is any one or a combination of more of champignon powder, ginger powder, tuckahoe powder, tangerine peel powder, broccoli powder, hawthorn powder and Chinese date powder.
6. The fucoidan-enriched tabletted candy according to claim 1, wherein the ratio of: the specification of the tablet candy is 0.2 g/tablet to 2.0 g/tablet.
7. Use of a candy tablet according to any one of claims 1 to 6 enriched with fucoidan for eliminating helicobacter pylori in the oral cavity and stomach.
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CN113854388A (en) * | 2021-09-27 | 2021-12-31 | 山东省农业科学院 | Probiotic tabletting candy containing undaria pinnatifida polysaccharide fermentation product and preparation method |
CN114916673A (en) * | 2022-06-02 | 2022-08-19 | 青岛特医堂生物科技有限公司 | Stomach nourishing and protecting nutritional powder |
CN115956644A (en) * | 2022-12-29 | 2023-04-14 | 广州兴欣堂生物科技有限公司 | Medicinal and edible food composition for resisting helicobacter pylori and preparation method thereof |
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
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CN113854388A (en) * | 2021-09-27 | 2021-12-31 | 山东省农业科学院 | Probiotic tabletting candy containing undaria pinnatifida polysaccharide fermentation product and preparation method |
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CN114916673A (en) * | 2022-06-02 | 2022-08-19 | 青岛特医堂生物科技有限公司 | Stomach nourishing and protecting nutritional powder |
CN115956644A (en) * | 2022-12-29 | 2023-04-14 | 广州兴欣堂生物科技有限公司 | Medicinal and edible food composition for resisting helicobacter pylori and preparation method thereof |
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