CN109939147A - A kind of Chinese medicine composition that treating acute and chronic pharyngitis, preparation and its application - Google Patents

A kind of Chinese medicine composition that treating acute and chronic pharyngitis, preparation and its application Download PDF

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CN109939147A
CN109939147A CN201910358162.5A CN201910358162A CN109939147A CN 109939147 A CN109939147 A CN 109939147A CN 201910358162 A CN201910358162 A CN 201910358162A CN 109939147 A CN109939147 A CN 109939147A
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parts
chinese medicine
medicine composition
chronic pharyngitis
acute
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吴维炎
陈思瑜
吴君学
吴娟
林天东
邢益涛
林学英
陈桂妃
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Abstract

It includes the bulk pharmaceutical chemicals of following parts by weight that the present invention, which provides a kind of Chinese medicine composition for treating acute and chronic pharyngitis, preparation and its application, the active component of the Chinese medicine composition: 15-25 parts of subprostrate sophora, 18-30 parts of the larva of a silkworm with batrytis, 8-12 parts of cicada slough, 9-15 parts of great burdock achene, 8-12 parts of campanulaceae, 8-12 parts of Radix Glycyrrhizae, 9-20 parts of rhizoma corydalis.Each component scientific compatibility of the present invention mutually acts synergistically, pharynx-clearing throat-benefiting, swelling and pain relieving, logical numbness stagnation resolvation, there is significant therapeutic effect to treatment acute and chronic pharyngitis, total effective rate is up to 100%, is up to 96.7% to acute laryngopharyngitis cure rate, is up to 92.5% to pharyngo-laryngitis chronica cure rate.

Description

A kind of Chinese medicine composition that treating acute and chronic pharyngitis, preparation and its application
Technical field
The present invention relates to technical field of traditional Chinese medicines, in particular to a kind of Chinese medicine composition for treating acute and chronic pharyngitis, preparation And its application.
Background technique
Acute and chronic pharyngitis is primarily referred to as under pharyngeal mucosa, mucous membrane and the diffusivity inflammation of lymphoid tissue, is often accompanied by other Upper respiratory disease is a kind of disease of pharynx very common in crowd.Clinical symptoms mainly with the congestion and swelling pain of bottleneck throat, gulp down It is not felt like oneself when pharynx as disease, abundant expectoration not mucofilin, fatiguability of talking, or gargle in brushing teeth, nausea and vomiting are easy when talking more, it is more Number is also with constitutional symptoms such as upper respiratory tract infection symptoms and loss of appetite such as fever, coughs.And current sphagitis illness rate It is very high.But in the prior art, for pharyngo-laryngitis chronica, often cure rate is not high, therefore is badly in need of a kind of Chinese medicine composition, can eradicate Above-mentioned disease.
Summary of the invention
For mirror with this, the present invention proposes the Chinese medicine composition, preparation and its application of a kind of acute and chronic pharyngitis, solves above-mentioned skill Art problem.
The technical scheme of the present invention is realized as follows:
A kind of Chinese medicine composition for treating acute and chronic pharyngitis, active component include the bulk pharmaceutical chemicals of following parts by weight: mountain 15-25 parts of beans root, 8-12 parts of cicada slough, 9-15 parts of great burdock achene, 8-12 parts of campanulaceae, 8-12 parts of Radix Glycyrrhizae, prolongs recklessly at 18-30 parts of the larva of a silkworm with batrytis 9-20 parts of rope.
Further, the active component of the Chinese medicine composition includes the bulk pharmaceutical chemicals of following parts by weight: 20 parts of subprostrate sophora, white 20 parts of bombyx batryticatus, 10 parts of cicada slough, 10 parts of great burdock achene, 10 parts of campanulaceae, 10 parts of Radix Glycyrrhizae, 10 parts of rhizoma corydalis.
Further, the active component of the Chinese medicine composition further includes the bulk pharmaceutical chemicals of following parts by weight: radix scrophulariae 15~25 Part, 3~8 parts of peppermint.
Further, the active component of the Chinese medicine composition further includes the bulk pharmaceutical chemicals of following parts by weight: 20 parts of radix scrophulariae, thin 5 parts of lotus.
Further, the present invention also provides a kind of Chinese medicinal composition preparations for treating acute and chronic pharyngitis, include the present invention The Chinese medicine composition of described in any item treatment acute and chronic pharyngitis, the Chinese medicinal composition preparation are decoction, granule, ball Agent, capsule, oral solution one kind.
Further, the Chinese medicine composition of the described in any item treatment acute and chronic pharyngitis of the present invention is anxious slow in preparation treatment Application in the drug of property sphagitis.
Compared with prior art, the beneficial effects of the present invention are:
The traditional chinese medicine composition of the invention, the bring down a fever carbuncle that disappears of subprostrate sophora is monarch in side;It is with great burdock achene, cicada slough, campanulaceae, the larva of a silkworm with batrytis Minister, great burdock achene heat-clearing, dissipate it is strongly fragrant, enter 12 warps and it is logical dissipate, solve the poison of swollen sore;The frivolous diverging of cicada slough, detumescence poison;Campanulaceae acrid flavour with With promoting the circulation of qi, clear larynx benefit diaphragm, dissipating bind are stagnant and reduce swelling hard for regulating the qi flowing in the channels, slightly warm in nature;The white deadlock negative Liver Channel wind dispelling that enters to faint opens numbness, reducing phlegm and resolving masses, altogether For ministerial drug;Assistant is with rhizoma corydalis regulating blood condition stasis-dispelling and pain-killing;Radix Glycyrrhizae lets out fire and promotes the production of body fluid, hundred poison of solution, coordinating the drug actions of a prescription.Each component scientific compatibility, phase Mutually synergistic effect, pharynx-clearing throat-benefiting, swelling and pain relieving, logical numbness stagnation resolvation have significant therapeutic effect to treatment acute and chronic pharyngitis.
In addition, being aided with peppermint on the basis of we, radix scrophulariae is minister, mint exorcising;Radix scrophulariae dissipates carbuncle swells, relieving heat toxin, knot Close great burdock achene, cicada slough, campanulaceae, the larva of a silkworm with batrytis is ministerial drug altogether;Further increase therapeutic effect.
The traditional chinese medicine composition of the invention is up to 100% to treatment acute and chronic pharyngitis total effective rate, wherein to acute laryngopharyngitis Cure rate is up to 96.7%, is up to 92.5% to pharyngo-laryngitis chronica cure rate, has to the therapeutic effect of pharyngo-laryngitis chronica larger prominent It is broken.
Specific embodiment
In order to be best understood from the technology of the present invention content, specific embodiment is provided below, the present invention is described further.
Experimental method used in the embodiment of the present invention is conventional method unless otherwise specified.
Material used in the embodiment of the present invention, reagent etc., are commercially available unless otherwise specified.
Subprostrate sophora: it is bitter in taste, it trembles with fear;It is toxic.Channel tropism attaches to the lung and stomach meridians.Major function is clearing heat and detoxicating, relieving sore-throat of reducing swelling.For fire Poison pents up, abscess of throat, gingivitis.
The larva of a silkworm with batrytis: nature and flavor are pungent salty, put down.Channel tropism enters liver, lung, stomach meridian.Major function expels endogenous wind to relieve convulsion, reducing phlegm and resolving masses.Control apoplexy Aphonia, frightened epilepsy, intermittent headache, sore-throat.Sore throat, scrofula tuberculosis.Wind sore urticaris, erysipelas, mazoitis.
Cicada slough: nature and flavor are sweet, tremble with fear.Channel tropism return lung, Liver Channel.Major function relieve heat moves back screen, spasmolysis except heat, relieving sore-throat, promoting eruption.With In anemopyretic cold, pharyngalgia, hoarse voice, measles without adequate eruption, rubella itch, cataract, convulsion, tetanus.
Great burdock achene: nature and flavor are pungent, bitter, tremble with fear.Channel tropism attaches to the lung and stomach meridians.Major function dispelling wind and heat from the body, promoting the dispersing function of the lung promoting eruption, relieving sore-throat of detoxifying. For anemopyretic cold, coughing with a lot of sputum, morbilli, rubeola, abscess of throat, mumps erysipelas, carbuncle sore tumefacting virus.
Campanulaceae: it is bitter in taste, pungent, it puts down.Channel tropism is distributed in lung channel.Major function promoting the dispersing function of the lung, relieving sore-throat, eliminating the phlegm, apocenosis.For phlegm of coughing More, chest distress, pharyngalgia, hoarse voice, lung carbuncle pyemesis, sore purulence is not at bursting.
Radix Glycyrrhizae: nature and flavor sweet and neutral.Channel tropism return heart, lung, spleen, stomach meridian.Major function is invigorated the spleen and benefited qi, clearing heat and detoxicating, and eliminating the phlegm stops Cough, relieving spasm to stop pain, coordinating the drug actions of a prescription.For weakness of the spleen and the stomach, fatigue and weakness, shortness of breath and palpitation, coughing with a lot of sputum, stomach duct and abdomen, four limbs contraction are suddenly ached Bitterly, carbuncle sore tumefacting virus alleviates drug toxicity, strong.
Rhizoma corydalis: nature and flavor are pungent, bitter, temperature.Channel tropism returns liver, the spleen channel.Major function promoting blood circulation, sharp gas, analgesic.For chest side of body, gastral cavity Abdomen pain, amenorrhea and algomenorrhea, postpartum stasis, tumbling and swelling.
Radix scrophulariae: nature and flavor are sweet, bitter, salty, slightly cold.Channel tropism return lung, stomach, kidney channel.Major function cool blood enriching yin, purging fire for removing toxin.With In consumption of YIN caused by febrile disease, the deep red polydipsia of tongue, febrile virulent maculae, Tianjin hinder constipation, hectic fever due to yin labor is coughed, hot eyes, pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus.
Peppermint: nature and flavor are pungent, cool.Channel tropism return lung, Liver Channel.Major function dispelling wind-heat.Refresh oneself, promoting eruption.For wind-heat sense Emit, wind-warm syndrome from the beginning of, headache, hot eyes, sore throat, aphtha, rubeola, morbilli, Breast bilges frowsty.
Embodiment 1
A kind of Chinese medicine composition for treating acute and chronic pharyngitis, active component include the bulk pharmaceutical chemicals of following weight: mountain beans Root 15g, larva of a silkworm with batrytis 18g, cicada slough 8g, great burdock achene 9g, campanulaceae 8g, Radix Glycyrrhizae 8g, rhizoma corydalis 9g.It is decocted using conventional method and soup is made Agent.
Embodiment 2
A kind of Chinese medicine composition for treating acute and chronic pharyngitis, active component include the bulk pharmaceutical chemicals of following weight: mountain beans Root 25g, larva of a silkworm with batrytis 30g, cicada slough 12g, great burdock achene 15g, campanulaceae 12g, Radix Glycyrrhizae 12g, rhizoma corydalis 20g.It is decocted using conventional method Decoction is made.
Embodiment 3
A kind of Chinese medicine composition for treating acute and chronic pharyngitis, active component include the bulk pharmaceutical chemicals of following weight: mountain beans Root 20g, larva of a silkworm with batrytis 20g, cicada slough 10g, great burdock achene 10g, campanulaceae 10g, Radix Glycyrrhizae 10g, rhizoma corydalis 10g.It is decocted using conventional method Decoction is made.
Embodiment 4
A kind of Chinese medicine composition for treating acute and chronic pharyngitis, active component include the bulk pharmaceutical chemicals of following weight: mountain beans Root 15g, larva of a silkworm with batrytis 18g, cicada slough 8g, great burdock achene 9g, campanulaceae 8g, Radix Glycyrrhizae 8g, rhizoma corydalis 9g, radix scrophulariae 15g, peppermint 3g.Using normal Rule method, which decocts, is made decoction.
Embodiment 5
A kind of Chinese medicine composition for treating acute and chronic pharyngitis, active component include the bulk pharmaceutical chemicals of following weight: mountain beans Root 25g, larva of a silkworm with batrytis 30g, cicada slough 12g, great burdock achene 15g, campanulaceae 12g, Radix Glycyrrhizae 12g, rhizoma corydalis 20g, radix scrophulariae 25g, peppermint 8g.It adopts It is decocted with conventional method and decoction is made.
Embodiment 6
A kind of Chinese medicine composition for treating acute and chronic pharyngitis, active component include the bulk pharmaceutical chemicals of following weight: mountain beans Root 20g, larva of a silkworm with batrytis 20g, cicada slough 10g, great burdock achene 10g, campanulaceae 10g, Radix Glycyrrhizae 10g, rhizoma corydalis 10g, radix scrophulariae 20g, peppermint 5g.It adopts It is decocted with conventional method and decoction is made.
In order to verify the beneficial effect of the traditional chinese medicine composition of the invention, by each embodiment of Chinese medicine composition of the invention into Row test, test method and result are as follows:
1, basic document: acute and chronic pharyngitis patient 420 are collected altogether;1~test group of test group 6, every group 30 acute Sphagitis patient;7~test group of test group 12, every group of 40 pharyngo-laryngitis chronicas.
2, clinical manifestation
The congestion and swelling pain of bottleneck throat does not feel like oneself when swallowing as disease, abundant expectoration not mucofilin, fatiguability of talking, or in brushing teeth It gargles, nausea and vomiting is easy when talking more, it is most also complete with upper respiratory tract infection symptoms and loss of appetite etc. such as fever, coughs Body symptom.
3, clinical criteria
(1) often have foreign matter feeling in throat, not out, pharynx not under.
(2) nasopharynx is dry uncomfortable, has sticky sample secretion to be not easy expectoration.
(3) the fluffy object of self-induction or there are viscous phlegm, Nausea and vomiting, gastric disorder causing nausea etc..
(4) serious person has trachyphonia, and pharyngalgia is attached most importance to morning.
(5) it has a headache, it is dizzy, it is out of strength.
(6) pharynx rear wall film is congested, dark red or in Marjoram Extract or have exudation to adhere to, lymph foilicie hyperplasia, and funiculus lateralis is red It is swollen or plump, outstanding to stop up plumpness of hanging down.
(7) nausea, retch, throat pain, have a bitter taste in the mouth, halitosis.
(8) acute laryngopharyngitis, caused by more affection of exogenous wind-heat, clinical sign fever, pharyngalgia dry, thirsty or hoarseness etc..
(9) pharyngo-laryngitis chronica, bottleneck throat are red and swollen congested, and throat has a foreign body sensation, pharynx not under, not out is pharyngeal frequent It is dry, sound hoarse, pharyngeal reflection sensitive when feeling bad of itching.
4, treatment method and the course for the treatment of: 1~test group of test group 6 respectively corresponds the Chinese medicine composition for taking Examples 1 to 6; 7~test group of test group 12 respectively corresponds the Chinese medicine composition for taking Examples 1 to 6;One dose per day is decocted in water for oral dose, point early supper After warmly take, day 2 times;Acute sore throat patient 3 days are 1 course for the treatment of, take 1~2 course for the treatment of.Chronic throat patient 5 days are 1 course for the treatment of, take 1 ~3 courses for the treatment of.
5, curative effect judging standard
Recovery from illness: bottleneck throat congestion and swelling pain, do not feel like oneself when swallowing disappearances, checks completely normal, clinical symptoms disappearance, half a year Afterwards without recurrence;
Effective: bottleneck throat congestion and swelling pain, do not feel like oneself when swallowing alleviation, and inspection takes an evident turn for the better, and clinical symptoms obviously change It is kind;
Invalid: bottleneck throat congestion and swelling pain does not feel like oneself when swallowing not alleviated or aggravates, and checks without being clearly better, clinical condition Shape slightly improves or without change.
6, acute laryngopharyngitis therapeutic effect
7, pharyngo-laryngitis chronica therapeutic effect
Show that the traditional chinese medicine composition of the invention has significant treatment to treatment acute and chronic pharyngitis by above-mentioned clinical test Effect, total effective rate are up to 100%, are up to 96.7% to acute laryngopharyngitis cure rate, are up to pharyngo-laryngitis chronica cure rate 92.5%.
8, typical case
Case one
On June 18th, 2015, perhaps certain, male, 36 years old, because there is bottleneck throat congestion and swelling pain, swallows in the wind-engaging that trots out at dusk It is unfavorable, itching throat and dry cough, not out, pharynx not under, pink tongue, yellow tongue fur, rapid pulse.Diagnosis: acute laryngopharyngitis gives in of the invention The decoction of drug composition decoction, totally 5 doses, day is one, divides and warmly takes after morning and evening dinner, is treated symptom and is almost recovered.
Case two
On January 20th, 2017, Xu certain, female, 15 years old, patient's pharyngeal discomfort 3 months.It has a delicate constitution usually, throat aches repeatedly Bitterly, chilly is cold, and pharyngeal discomfort aggravates after blowing to the cold, conscious dysphagia, seemingly there is phlegm between larynx, not out, pharynx not under. Pale tongue with white fur deep thready pulse.Physical examination: pharyngeal unrestrained swollen, pharynx rear wall lymph foilicie hyperplasia.Heart and lung auscultation is without exception.Diagnosis: chronic throat Inflammation gives Chinese medicine composition decoction decoction of the invention, and totally 5 doses, day is one, divides and warmly takes after morning and evening dinner, through treatment pharyngeal discomfort, gulps down It swallows unfavorable symptom to turn for the better by and large, further consultation on January 28 in 2017, it is continuous to keep the treatment of 7 doses of front, it is almost recovered by follow-up and does not recur.
Case three
On January 8th, 2018, Chen, female, 25 years old, because stay up late chase after play after there is bottleneck throat congestion and swelling pain, in conscious larynx if any Foreign matter seemingly has phlegm, dysphagia, not out, pharynx not under, dry throat and mouth, tongue is red, yellow and greasy fur, rapid pulse.Diagnosis: acute pharynx Laryngitis gives Chinese medicine composition decoction decoction of the invention, and totally 3 doses, day is one, and 500ml decocting takes 300ml points of temperature after morning and evening dinner Clothes are treated symptom and are almost recovered.
9, adverse reaction is observed
In treatment observation case, adverse reaction patient is found no, shows that Chinese medicine composition of the invention safely may be used It leans on.
Granule, pill, capsule, oral solution can be also prepared by a conventional method into Chinese medicine composition of the invention, answer For treating acute and chronic pharyngitis.
To sum up, Chinese medicine composition of the invention has remarkable result to treatment acute and chronic pharyngitis, especially to chronic throat Scorching therapeutic effect has compared with quantum jump.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention Within mind and principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.

Claims (6)

1. a kind of Chinese medicine composition for treating acute and chronic pharyngitis, which is characterized in that its active component includes following parts by weight Bulk pharmaceutical chemicals: 15-25 parts of subprostrate sophora, 18-30 parts of the larva of a silkworm with batrytis, 8-12 parts of cicada slough, 9-15 parts of great burdock achene, 8-12 parts of campanulaceae, Radix Glycyrrhizae 8- 12 parts, 9-20 parts of rhizoma corydalis.
2. a kind of Chinese medicine composition for treating acute and chronic pharyngitis according to claim 1, which is characterized in that its active group Point including following parts by weight bulk pharmaceutical chemicals: 20 parts of subprostrate sophora, 20 parts of the larva of a silkworm with batrytis, 10 parts of cicada slough, 10 parts of great burdock achene, 10 parts of campanulaceae, 10 parts of Radix Glycyrrhizae, 10 parts of rhizoma corydalis.
3. a kind of Chinese medicine composition for treating acute and chronic pharyngitis according to claim 1, which is characterized in that its active group It point further include the bulk pharmaceutical chemicals of following parts by weight: 15~25 parts of radix scrophulariae, 3~8 parts of peppermint.
4. a kind of Chinese medicine composition for treating acute and chronic pharyngitis according to claim 3, which is characterized in that its active group It point further include the bulk pharmaceutical chemicals of following parts by weight: 20 parts of radix scrophulariae, 5 parts of peppermint.
5. a kind of Chinese medicinal composition preparation for treating acute and chronic pharyngitis, which is characterized in that include any one of claims 1 to 3 The Chinese medicine composition of the treatment acute and chronic pharyngitis, the Chinese medicinal composition preparation are decoction, granule, pill, capsule Agent, oral solution one kind.
6. the Chinese medicine composition of the described in any item treatment acute and chronic pharyngitis of Claims 1 to 4 is in preparation treatment acute and chronic pharynx Application in the drug of laryngitis.
CN201910358162.5A 2019-04-30 2019-04-30 A kind of Chinese medicine composition that treating acute and chronic pharyngitis, preparation and its application Pending CN109939147A (en)

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CN115252724A (en) * 2022-07-27 2022-11-01 佛山市高明区人民医院 Traditional Chinese medicine composition for treating pharyngitis, product and preparation method

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